questionId
int32
337
40.1k
question
stringlengths
11
168
question_types
listlengths
1
4
image
imagewidth (px)
200
7.07k
docId
int32
279
12.9k
ucsf_document_id
stringlengths
8
8
ucsf_document_page_no
stringclasses
160 values
answers
listlengths
1
14
1,122
What is the date of the signature of the chairman of the Division of clinical research?
[ "handwritten", "layout" ]
512
zfkf0226
5
[ "5/8/07" ]
1,123
Name of the first person in the To list?
[ "handwritten", "form" ]
521
zsjf0226
1
[ "PJ Daniels", "pj Daniels" ]
1,124
When did Regulatory affairs department receive this letter?
[ "layout" ]
503
kmjf0226
1
[ "Feb 19 2007", "FEB 19 2007" ]
1,125
from whose desk this letter is written ?
[ "form" ]
521
zsjf0226
1
[ "Timothy J. Gumbleton", "timothy J Gumbleton" ]
1,126
Whose letter's copy is attached?
[ "free_text" ]
521
zsjf0226
1
[ "DR. Mitchell", "Dr. Mitchell" ]
1,128
what is the date mentioned ?
[ "form" ]
522
hmjf0226
1
[ "February 6, 1996", "february 6 , 1996" ]
1,129
to whom this letter is written ?
[ "form" ]
522
hmjf0226
1
[ "Dr. K. KItazawa", "Dr . k. Kitazawa" ]
1,130
this letter is written by whom ?
[ "form" ]
522
hmjf0226
1
[ "T. Suzuki", "Tsuyoshi Suzuki , M S ." ]
1,131
Which laboratory is T. Suzuki associated with ?
[ "others", "layout" ]
522
hmjf0226
1
[ "Drug Safety Research Laboratories", "drug safety research laboratories ." ]
1,132
what is the date mentioned in the letter
[ "layout" ]
524
pljf0226
1
[ "August 8, 2002", "august 8 , 2002" ]
1,133
What is the name of the industry given here?
[ "layout" ]
524
pljf0226
1
[ "TAKEDA CHEMICAL INDUSTRIES, LTD.", "Takeda chemical industries, LTD ." ]
1,134
to whom this letter is written ?
[ "layout" ]
524
pljf0226
1
[ "Dr. Claire Thom", "Dr. Thom" ]
1,135
what is the name mentioned in CC
[ "layout" ]
524
pljf0226
1
[ "Mr. S. Hamanaka", "Mr . S . Hamanaka" ]
1,136
Who sent this letter?
[ "layout" ]
524
pljf0226
1
[ "Katsuhisa Saito", "katsuhisa saito" ]
1,137
what is Ref: code mentioned ?
[ "form", "layout" ]
524
pljf0226
1
[ "TPNA-TS-020808" ]
1,138
What is the venue mentioned in the document?
[ "form", "layout" ]
526
pljf0226
6
[ "TPNA, Chicago" ]
1,139
What is the date mentioned in the document?
[ "form", "layout" ]
526
pljf0226
6
[ "Monday, 12 and Tuesday, 13 August 2002" ]
1,140
what is the fax number mentioned in the letter at the top?
[ "layout" ]
526
pljf0226
6
[ "06 6204 2244" ]
1,141
what is the date and time mentioned ?
[ "form" ]
527
sljf0226
1
[ "10/27/93 09:36:07" ]
1,142
what is mentioned in the subject ?
[ "form" ]
527
sljf0226
1
[ "Pioglitazone statement", "pioglitazone statement" ]
1,143
To whom this email was send?
[ "form" ]
527
sljf0226
1
[ "PETER J. DANIELS", "PJ DANIEL--PW17PO PETER J. DANIELS" ]
1,144
what is the date mentioned in the forwarding note ?
[ "others", "layout" ]
527
sljf0226
1
[ "10/26/93", "10/26/93 15:44" ]
1,145
what is the time mentioned in the forwarding note ?
[ "others", "layout" ]
527
sljf0226
1
[ "15:44" ]
1,146
To whom this email was forwaded?
[ "form" ]
527
sljf0226
1
[ "RUPPEL, PATRICIA", "PLRUPPEL--RCC1 RUPPEL, PATRICIA" ]
1,147
what is the name of the company
[ "free_text", "layout" ]
528
zsjf0226
2
[ "THE UPJOHN COMPANY" ]
1,148
what is the date and year mentioned ?
[ "layout" ]
528
zsjf0226
2
[ "September 21, 1993", "september 21 , 1993" ]
1,150
Which company is mentioned in the letterhead?
[ "free_text", "layout" ]
528
zsjf0226
2
[ "THE UPJOHN COMPANY" ]
1,151
in which country the upjohn company is located ?
[ "free_text", "layout" ]
528
zsjf0226
2
[ "U.S.A", "USA" ]
1,152
what is the fax mentioned ?
[ "free_text", "layout" ]
530
pljf0226
3
[ "06 6204 2244" ]
1,153
what is year date and time mentioned?
[ "free_text", "layout" ]
530
pljf0226
3
[ "2002 08/08 21:49" ]
1,154
what is the name of the division ?
[ "layout" ]
530
pljf0226
3
[ "TAKEDA DEVELOP DIVISION", "Takeda Develop division" ]
1,155
to whom they can ask directly to disclose the details of "promotion study"?
[ "free_text", "layout" ]
530
pljf0226
3
[ "FDA" ]
1,157
what is the date mentioned in the letter
[ "layout" ]
531
syjf0226
1
[ "8 January 2003", "8 january 2003" ]
1,158
To whom this letter is addressed?
[ "form", "layout" ]
531
syjf0226
1
[ "MPDRAP I Leader" ]
1,159
what is mentioned in the CC?
[ "form", "layout" ]
531
syjf0226
1
[ "CEOs and General Managers of Pharmaceutical Units", "CEOs and general managers of pharmaceutical units" ]
1,160
combination therapy in the us market accounts for how much % of total actos sales .
[ "free_text", "layout" ]
531
syjf0226
1
[ "64", "64%" ]
1,177
What is the due date to evaluate data from actos 507?
[ "table/list", "layout" ]
535
qtjf0226
4
[ "August 5" ]
1,178
who is the lead responsibility for developing additional monitoring plan for actos 508
[ "table/list", "layout" ]
535
qtjf0226
4
[ "Amy Hagaman", "Amy hagaman" ]
1,179
what is the due date for "draft justification for actos 508" ?
[ "table/list", "layout" ]
535
qtjf0226
4
[ "August 12", "august 12" ]
1,180
when was this last updated ?
[ "form", "layout" ]
535
qtjf0226
4
[ "August 1, 2002", "august 1, 2002" ]
1,181
Who is the lead responsible person for draft justification for actos 508?
[ "table/list", "layout" ]
535
qtjf0226
4
[ "Amy Hagaman/Alfonso Perez" ]
1,195
Which is the core organization of Takeda pharmaceutical Company?
[ "free_text", "layout" ]
543
lmjf0226
2
[ "Pharmaceutical development Division", "Pharmaceutical Development Division" ]
1,196
Who made the opening remarks ?
[ "free_text", "layout" ]
543
lmjf0226
2
[ "Dr. Kitazawa" ]
1,197
When is the clinical expert meeting scheduled?
[ "free_text", "layout" ]
543
lmjf0226
2
[ "October 1 and 2", "for October 1 and 2." ]
1,198
what is the date mentioned in the given information ?
[ "form", "layout" ]
539
nqjf0226
1
[ "20 April 2006", "20 april 2006" ]
1,199
What is the meeting time mentioned here?
[ "form", "layout" ]
539
nqjf0226
1
[ "4:00pm - 5:00pm" ]
1,200
what is the place mentioned ?
[ "form", "layout" ]
539
nqjf0226
1
[ "Meeting Room 403", "meeting room 403" ]
1,201
Why was it suggested to prepare non-clinical "White paper"?
[ "free_text", "layout" ]
543
lmjf0226
2
[ "to address the bladder issue", "to address the bladder issue." ]
1,202
who will forward the article regarding rosiglitazone and non clinical bladder data to andy ?
[ "free_text", "layout" ]
539
nqjf0226
1
[ "Mondira" ]
1,203
What date is the meeting scheduled to develop the overall structure of the document?
[ "free_text", "layout" ]
539
nqjf0226
1
[ "in early May" ]
1,204
Who presented an outline of the Cohen hypothesis?
[ "free_text", "layout" ]
540
myjf0226
4
[ "Philip Collett" ]
1,205
What is significant in the development of calculi?
[ "free_text", "layout" ]
540
myjf0226
4
[ "Raising the pH of male rat urine above 6.5" ]
1,206
What is the correlation observed in cohen's paper?
[ "free_text", "layout" ]
540
myjf0226
4
[ "0.61" ]
1,207
Why didn't rats eliminate calculi as humans do?
[ "free_text", "layout" ]
540
myjf0226
4
[ "Because rats are quadropeds", "Because rats are quadropeds." ]
1,208
What is the fullform of MAA?
[ "others", "free_text" ]
547
gmjf0226
1
[ "Marketing Authorization Application" ]
1,209
Which forum is mentioned in this document?
[ "free_text", "layout" ]
547
gmjf0226
1
[ "Takeda Global Risk Management Forum", "Takeda Global Risk Management Forum/March 22, 2004" ]
1,211
What is the issued date of this document?
[ "layout" ]
542
jsjf0226
1
[ "august 13, 2002", "August 13, 2002" ]
1,212
Who is the Director of Nonclinical Safety and Efficacy?
[ "layout" ]
542
jsjf0226
1
[ "David baron", "David Baron" ]
1,213
Who described tumor promoter-model study?
[ "free_text" ]
542
jsjf0226
1
[ "dr. el-hage", "Dr. El-Hage" ]
1,214
What is the duration of daily dosing?
[ "free_text" ]
542
jsjf0226
1
[ "32-weeks", "32-weeks after BBN." ]
1,215
Who updated the CEO on August 6?
[ "free_text" ]
541
myjf0226
2
[ "Mr. Saito" ]
1,216
By when should TPNA send outline of response to TCI ?
[ "free_text" ]
541
myjf0226
2
[ "August 19", "by August 19" ]
1,217
When will Mr. Saito present outline to CEO?
[ "free_text" ]
541
myjf0226
2
[ "August 20", "on August 20" ]
1,218
By when will the document be finalized?
[ "free_text" ]
541
myjf0226
2
[ "August 26", "by August 26" ]
1,219
When will the FDA Conference Call be held?
[ "layout" ]
545
fsjf0226
1
[ "July 31, 2002" ]
1,220
What is the heading of the document?
[ "layout" ]
546
qtjf0226
1
[ "ACTOS FDA RESPONSE TASK FORCE-TPNA" ]
1,221
How many key issues does the FDA have with respect to the non-clinical data related to bladder tumors?
[ "others", "free_text" ]
546
qtjf0226
1
[ "The FDA has 3 key issues with respect to the non-clinical data related to bladder tumors.", "3" ]
1,222
What plan is developed by TPNA?
[ "others", "free_text" ]
546
qtjf0226
1
[ "TPNA will develop monitoring plan.", "monitoring plan" ]
1,223
What is TPNA's goal?
[ "others", "free_text" ]
546
qtjf0226
1
[ "is to supply justification to support maintaining current labeling." ]
1,224
When was this document last updated?
[ "layout" ]
548
qtjf0226
8
[ "August 1, 2002" ]
1,225
What is the last point in the table?
[ "table/list", "layout" ]
548
qtjf0226
8
[ "Evaluate Impact on Tak-559", "EVALUATE IMPACT ON TAK-559" ]
1,227
What is the Draft's Due Date?
[ "table/list", "layout" ]
548
qtjf0226
8
[ "August 5" ]
1,228
Which benefit start after 1 year of service?
[ "table/list", "layout" ]
501
ttjf0226
5
[ "Extended Disability", "extended disability" ]
1,229
What is Ms Wakamatsu's role in Dept. Strategic Development?
[ "free_text", "layout" ]
543
lmjf0226
2
[ "Assistant manager", "Assistant Manager" ]
1,230
Which drug's toxicity study results will be discussed ?
[ "table/list", "free_text", "layout" ]
526
pljf0226
6
[ "pioglitazone" ]
1,231
How many pages are there in total as part of this document?
[ "layout" ]
535
qtjf0226
4
[ "7" ]
1,233
Who challenged authorities regrading implementing monitoring plan?
[ "free_text", "layout" ]
540
myjf0226
4
[ "Takeda Europe" ]
1,234
What content is high in male rat urine?
[ "free_text", "layout" ]
540
myjf0226
4
[ "protein", "protien content" ]
1,235
What kind of meeting is mentioned in this letter?
[ "layout" ]
550
myjf0226
1
[ "ACTOS FDA RESPONSE MEETING" ]
1,239
what kind of drug is used to treat the group of rats?
[ "free_text" ]
550
myjf0226
1
[ "Pioglitazone", "pioglitazone" ]
1,240
In the rat oncogenicity study, what was observed in male rats?
[ "free_text" ]
552
myjf0226
3
[ "thickening of the bladder and hypertrophy of the urothelium" ]
1,241
What is the due date to conduct review meeting for FDA package?
[ "table/list" ]
551
qtjf0226
7
[ "August 22" ]
1,242
What is the time span where no tumors are seen?
[ "free_text" ]
552
myjf0226
3
[ "shorter term (12 month)" ]
1,243
Who is the lead responsible person for the compilation of FDA package?
[ "table/list" ]
551
qtjf0226
7
[ "Larry Hancock" ]
1,244
According to mouse oncogenicity study, what was seen male mice only?
[ "free_text" ]
552
myjf0226
3
[ "hyperplasia" ]
1,245
what kind of cell tumours experienced the same frequency when group of rats treated with pioglitazone?
[ "free_text" ]
550
myjf0226
1
[ "transitional", "transitional cell tumors" ]
1,246
who conducted robust program?
[ "free_text" ]
552
myjf0226
3
[ "TCI" ]
1,247
What is the task assigned to David Baron?
[ "table/list" ]
551
qtjf0226
7
[ "Send nonclinical rationale/justification section to medical writing for compilation", "Send nonclinical rationale/justification section to medical writing for compilation." ]
1,248
Who is responsible for sending package to TCI/EU for review?
[ "table/list" ]
551
qtjf0226
7
[ "Mary Ramstack" ]
1,249
What is the due date for sending FDA Document to Regulatory Affairs?
[ "table/list" ]
551
qtjf0226
7
[ "August 26" ]
1,251
What is the last updated date mentioned in this document?
[ "layout" ]
551
qtjf0226
7
[ "August 1, 2002", "August 1, 2002" ]
1,253
Which product's liability claims are described here?
[ "layout" ]
554
hrjf0226
1
[ "ACTOS PRODUCTS", "ACTOS PRODUCTS LIABILITY CLAIMS" ]
1,254
What is the date mentioned in this document at the bottom?
[ "layout" ]
554
hrjf0226
1
[ "1/11/2007" ]
1,255
Mention the first name listed in the "apologies"?
[ "table/list" ]
553
ltjf0226
1
[ "Professor Ele Ferrannini" ]
1,256
What is the exhibit number?
[ "handwritten", "form", "others" ]
554
hrjf0226
1
[ "52" ]
1,259
when was the last meeting/conference call held on ?
[ "free_text", "layout" ]
553
ltjf0226
1
[ "15th October 2005", "15 October 2005" ]
1,260
What is the exhibit number?
[ "form" ]
542
jsjf0226
1
[ "107" ]
1,262
what is the date mentioned under the title - " minutes of conference call"?
[ "form" ]
553
ltjf0226
1
[ "Monday 28th November 2005", "monday 28th november 2005", "28th November 2005" ]
1,264
What is the heading of this document?
[ "layout" ]
558
xqjf0226
2
[ "Rationale for 3 segments", "Rationale for 3 Segments" ]
1,265
what is the title of chapter 3?
[ "layout" ]
556
jpjf0226
3
[ "Document Storage Period", "document storage period" ]