Upload taxonomy_rxn_types.json
Browse files- taxonomy_rxn_types.json +97 -0
taxonomy_rxn_types.json
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| 1 |
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{
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| 2 |
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"Carbon-Carbon_Bond_Formation": [
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"Chloro Suzuki coupling",
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| 4 |
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"Iodo Miyaura boration",
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"Grignard ester substitution",
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| 6 |
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"Bromo Miyaura boration",
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| 7 |
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"Chloro Miyaura boration",
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| 8 |
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"Claisen-Schmidt condensation",
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"Bromo Stille reaction",
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| 10 |
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"Knoevenagel condensation",
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| 11 |
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"Triflyloxy Sonogashira coupling",
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| 12 |
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"Triflyloxy Miyaura boration",
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| 13 |
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"Bromo Sonogashira coupling",
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| 14 |
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"Chloro Sonogashira coupling",
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| 15 |
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"Iodo Suzuki coupling",
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| 16 |
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"Grignard + acid chloride ketone synthesis",
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| 17 |
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"Bromo Grignard reaction",
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| 18 |
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"Iodo Grignard reaction",
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| 19 |
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"Iodo Stille reaction",
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| 20 |
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"Friedel-Crafts acylation",
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| 21 |
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"Keto alpha-alkylation",
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"Bromo Suzuki coupling",
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"Iodo Sonogashira coupling",
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"Weinreb ketone synthesis",
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"Wittig olefination",
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"Chloro Grignard reaction",
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"Chloro Stille reaction"
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],
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"Carbon-Heteroatom_Bond_Formation": [
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"Esterification",
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"Iodo N-methylation",
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| 32 |
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"Mesyloxy N-alkylation",
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"Mitsunobu imide reaction",
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"N-Cbz protection",
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"Weinreb amide synthesis",
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"Ester Schotten-Baumann",
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"Iodo N-alkylation",
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| 38 |
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"Williamson ether synthesis",
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"Bromo Buchwald-Hartwig amination",
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"Mitsunobu ester synthesis",
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"Mitsunobu aryl ether synthesis",
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"Carboxy to carbamoyl",
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"Alcohol + amine condensation",
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| 44 |
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"Chloro N-alkylation",
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| 45 |
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"Amide Schotten-Baumann",
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"Bromo N-alkylation",
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"Fischer-Speier esterification",
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"Steglich esterification",
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"Methyl esterification",
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"Iodo Buchwald-Hartwig amination",
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"Carbamate Schotten-Baumann",
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"Sulfonic ester Schotten-Baumann",
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"Carboxylic acid + amine condensation",
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"Mitsunobu sulfonamide reaction",
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"N-Boc protection",
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"Sulfonamide Schotten-Baumann",
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"Chloro Buchwald-Hartwig amination"
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],
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"Deprotection_Reactions": [
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"CO2H-Et deprotection",
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"Ester hydrolysis",
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"O-TBS deprotection",
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| 63 |
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"N-Boc deprotection",
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| 64 |
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"O-TBDPS deprotection",
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| 65 |
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"CO2H-Me deprotection",
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| 66 |
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"N-Cbz deprotection",
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| 67 |
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"O-Bn deprotection",
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| 68 |
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"O-TIPS deprotection",
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| 69 |
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"CO2H-tBu deprotection"
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| 70 |
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],
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"Functional_Group_Interconversion": [
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"Iodination",
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"Hydroxy to chloro",
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"Ketone to alcohol reduction",
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"Chlorination",
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"Methoxy to hydroxy",
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"Aldehyde Dess-Martin oxidation",
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| 78 |
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"Wohl-Ziegler bromination",
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"Bechamp reduction",
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"Carboxylic ester + amine reaction",
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| 81 |
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"Bromination",
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| 82 |
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"Bromo Grignard preparation",
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| 83 |
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"Ketone Dess-Martin oxidation",
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"Aldehyde reductive amination",
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"Sulfanyl to sulfonyl",
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"Darzens bromination",
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"SNAr ether synthesis",
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"Ketone reductive amination",
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"Darzens chlorination",
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| 90 |
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"Ester to alcohol reduction"
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],
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| 92 |
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"Other_Reactions": [
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"Isocyanate + alcohol reaction",
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| 94 |
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"Isocyanate + amine urea coupling",
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| 95 |
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"Pinner reaction"
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| 96 |
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]
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}
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