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BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1036-4 | 12916_2018_1036_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | General appraisal This man uscript addresses an important aspect of the dietary factors and physical function relationship in older adults. The manuscript is clear, concise and well -referenced with up -to-date articles. It has several strengths, among which the repeated measurement s of food intake during follow -up i... | null | 2018-01-06T00:00:00 | CC BY 4.0 | true | -7.737837 | 452 | others | generate | false | false | [
{
"claim": "A diet quality score would help determine whether processed meat intake reflects a generally lower-quality diet; this analysis is missing.",
"category": "experiments-scope",
"target": "experiments",
"specific": true
},
{
"claim": "p. 4, line 39 presents frailty as an outcome rela... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1036-4 | 12916_2018_1036_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | COMMENTS TO THE AUTHORS TITLE: CONSUMPTION OF MEAT IN RELATION TO PHYSICAL FUNCTIONING IN THE SENIORS -ENRICA COHORT FEBRUARY 7, 2018 _________________________ ______________________________________________________ This manuscript aimed to examine the prospective association between meat (processed meat, red meat, and ... | null | 2018-02-08T00:00:00 | CC BY 4.0 | true | -5.682011 | 316 | others | generate | false | false | [
{
"claim": "Page 4, line 47, “non-American populations” is ambiguous; clarify whether it means studies conducted outside the U.S.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "Pages 5, lines 69–71, do not report whether participants lost to f... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1045-3 | 12916_2018_1045_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This artic le by Lu et al. is an interesting and comprehensive assessment of the antimalarial properties of methylene blue (MB). Their review of clinical and mechanistic studies of MB safety and efficacy in the treatment of malaria is very timely, given renewed inter est in the potent antimalarial properties of this dr... | null | 2018-02-09T00:00:00 | CC BY 4.0 | true | -6.665045 | 244 | others | generate | false | false | [
{
"claim": "The review should discuss and cite Siciliano et al. (2017) on methylene blue synergy with NADPH synthesis inhibition in mature gametocytes and transmission blocking.",
"category": "related-work",
"target": "related-work",
"specific": true
},
{
"claim": "The review should discuss ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1045-3 | 12916_2018_1045_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | The authors have undertaken a rare and laborious search of the available literature on methylene blue therapy for malaria dating back to the 1890s. This is highly commendable and their effort offers otherwise very difficult to ascertain facts and history. The absence of page numbers and repeating line numbers per page ... | null | 2018-02-20T00:00:00 | CC BY 4.0 | true | -7.514277 | 916 | others | generate | false | false | [
{
"claim": "The review copy lacks page numbers and per-page line numbering, making cross-reference difficult.",
"category": "clarity/presentation",
"target": "presentation",
"specific": false
},
{
"claim": "The manuscript wrongly portrays methylene blue as a dominant pre-synthetic antimalari... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1045-3 | 12916_2018_1045_ReviewerReport_V0_R3 | Reviewer 3 | null | null | null | This is a very important article for new, inexpensive malaria treatment regimens. The article is very cl ear and sheds important light on the use of MB in antimalarial therapy. However, the list of the 474 references retrieved by the authors should be added in "additional data". A very small detail: authors should add ... | null | 2018-01-11T00:00:00 | CC BY 4.0 | true | -4.355613 | 82 | others | generate | false | false | [
{
"claim": "The list of 474 references retrieved by the authors should be added to the additional data.",
"category": "reproducibility/details",
"target": "experiments",
"specific": true
},
{
"claim": "The first sentence should add “in human” to “Malaria remains the most important parasitic ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1057-z | 12916_2018_1057_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | Thank you for asking me to review this interesting and well written paper. I'm very supportive of publication . 1. The paper argues against a linear and mechanistic view of implementation processes and suggests that systems and complexity theories offer useful correctives to a 'pipeline' model of implementation. 2. CAS... | null | 2018-02-13T00:00:00 | CC BY 4.0 | true | -7.387093 | 488 | others | generate | false | false | [
{
"claim": "The paper overstates how much the pipeline model of implementation still holds sway.",
"category": "unsupported-claim",
"target": "claims",
"specific": true
},
{
"claim": "The paper should explain pipeline models’ appeal to managers and clinicians through everyday causal accounts... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1057-z | 12916_2018_1057_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | "When complexity science meets implementation science" draws from complexity science to help explain the difficulty of implementation and to improve our success in conducting implementation. The authors apply complexity science concepts to tw o cases of implementation. The first part of the paper (pp. 1 -15) presents f... | null | 2018-01-30T00:00:00 | CC BY 4.0 | true | -7.45496 | 618 | others | generate | false | false | [
{
"claim": "The discussion should also consider how research funding, careers, and disciplinary reputations incentivize clear-cut findings.",
"category": "assumptions",
"target": "presentation",
"specific": false
},
{
"claim": "Figure 5 does not capture the breadth and distinctiveness of com... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1057-z | 12916_2018_1057_ReviewerReport_V0_R3 | Reviewer 3 | null | null | null | Braithwaite and colleagues have come submitted a paper entitled "When complexity science meets implementation science: The theoreti cal and empirical analysis of systems change" for consideration of publication to BMC Medicine. The article highlights "what implementation science can learn from complexity science" in re... | null | 2018-02-09T00:00:00 | CC BY 4.0 | true | -7.480705 | 1,116 | others | generate | false | false | [
{
"claim": "The manuscript is too long and needs editing to reduce its length.",
"category": "clarity/presentation",
"target": "presentation",
"specific": false
},
{
"claim": "The discussion on pages 5 and 10, including calling complexity science “more sophisticated,” unfairly disparages red... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1057-z | 12916_2018_1057_ReviewerReport_V0_R4 | Reviewer 4 | null | null | null | I thank the editors for the opportunity to review this manuscript, to both challenge and inform my thinking about the ways in which implementation science contrasts with, though can potentially be complement ary to, complexity science and systems based approaches. This paper can make an important contribution to knowle... | null | 2018-01-26T00:00:00 | CC BY 4.0 | true | -7.333086 | 538 | others | generate | false | false | [
{
"claim": "The two case studies need more detail to explain how complexity science facilitated implementation of system-level improvements.",
"category": "reproducibility/details",
"target": "experiments",
"specific": true
},
{
"claim": "The manuscript may contain one or two grammatical err... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1058-y | 12916_2018_1058_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | The authors are to be commended for undertaking this research. The conclusions are sound based on the empirical evidence provided. The analytical approach is appropriate. | null | 2018-03-01T00:00:00 | CC BY 4.0 | true | 1.027444 | 29 | openai_gpt | generate | false | false | [] |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1058-y | 12916_2018_1058_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | This paper looks at whether those who in 2012 had high use of opioids (by 3 different measures, with 4 levels within each) have high health car e costs (relative to non high 2012 opioid users) in 2013. The previous literature has only looked at whether those who have opioid use disorders (OUD) have high costs, not whet... | null | 2018-03-09T00:00:00 | CC BY 4.0 | true | -7.927509 | 657 | others | generate | false | false | [
{
"claim": "The restriction to multiregion commercial plans is insufficiently explained; include public plans, or provide a rationale and plan-type breakdown, especially for Medicaid.",
"category": "experiments-scope",
"target": "experiments",
"specific": true
},
{
"claim": "Requiring contin... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1059-x | 12916_2018_1059_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | General Remarks The manuscript focuses on a relevant topic of cognitive impairment and the dementia - a worldwide health problem. Several systematic reviews and meta -analyses have been published of epidemiologic studies t hat explored the relationship of obesity in midlife with risk of dementia at old age. However, th... | null | 2018-02-26T00:00:00 | CC BY 4.0 | true | -7.12473 | 202 | others | generate | false | false | [
{
"claim": "The Methods report 1,233 participants, whereas Table 1 reports 1,249; the study-group size should be consistent.",
"category": "reproducibility/details",
"target": "experiments",
"specific": true
},
{
"claim": "Figure 3’s legend describes waist circumference change, but the figur... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1059-x | 12916_2018_1059_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | This manuscript explores the relationship between patterns of adiposity, indexes of vascular health, and cognitive test performance in the 1946 British Birth Cohort. Prospective height, weight and waist circumference data at ages 36, 43, 53, and 60 -64, as well as cognitive and vascular function data at age 60 -64 were... | null | 2018-03-08T00:00:00 | CC BY 4.0 | true | -7.122417 | 265 | others | generate | false | false | [] |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1060-4 | 12916_2018_1060_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | Overall, I think this is a well written manuscript. Major issues: Methods MIS provide dat a on ITN use rate and exposure to IRS, as well as treatment seeking behaviour. It is well known that the anti -malarial treatment rate has a major influence on prevalence. The authors should include treatment seeking and vector co... | null | 2018-03-20T00:00:00 | CC BY 4.0 | true | -7.847843 | 746 | others | generate | false | false | [
{
"claim": "The analysis omits MIS data on ITN use, IRS exposure, and treatment-seeking behavior without explaining why these covariates were excluded.",
"category": "experiments-scope",
"target": "experiments",
"specific": true
},
{
"claim": "Travel time to cities over 50,000 is a poor prox... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1060-4 | 12916_2018_1060_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | Spatio -temporal mapping of Madagascar's Malaria Indicator Survey results to assess Plasmodium falciparum endemicity trends between 2011 and 2016. The authors used three MIS data in Madagascar and suite of socioeconomic and environmental covariates in a Bayesian geostatistical spatio -temporal model to map the prevalen... | null | 2018-03-14T00:00:00 | CC BY 4.0 | true | -7.733422 | 486 | others | generate | false | false | [
{
"claim": "The abstract should report how the population living in high- and low-endemicity areas changed over time.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "The introduction lacks historical context on malaria control activities in Mad... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1062-2 | 12916_2018_1062_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | General comments 1. This paper reports on a meta -regression of 16 prospective studies that test the link between sedentary behavio ur ('sitting time') and all -cause mortality. Both self -reported and devise -based measures are tested to see if differences exist in the way the exposure is assessed. 2. Results suggest ... | null | 2018-03-12T00:00:00 | CC BY 4.0 | true | -7.386285 | 726 | others | generate | false | false | [
{
"claim": "The manuscript does not establish its unique contribution relative to prior sedentary-behavior–mortality analyses, especially Ekelund et al. (2016).",
"category": "novelty",
"target": "claims",
"specific": true
},
{
"claim": "The Introduction and Discussion should explain that co... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1062-2 | 12916_2018_1062_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | GENERAL COMMENTS: Ku and colleagues' manuscript presents a meta -analysis of prospective cohort studies to quantify the dose -response association between daily sitting time and all -cause mortality in adults, and to determin e a cut -off point above which health is impaired. Based on data from more than 1 million peop... | null | 2018-03-09T00:00:00 | CC BY 4.0 | true | -7.552013 | 628 | others | generate | false | false | [
{
"claim": "The authors do not clarify whether they contacted studies excluded for missing sitting-time cut-offs (n=3) or inadequate physical-activity adjustment (n=3) to obtain the required data.",
"category": "reproducibility/details",
"target": "experiments",
"specific": true
},
{
"claim"... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1065-z | 12916_2018_1065_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | In this manuscript, Larsson et al. performed a Mendelian randomization analysis to examine if serum magnesium levels may be causally associated with coronary artery disease (CAD). The authors used summa ry-level data from the CARDIoGRAMplusC4D consortium's 1000 Genomes -based genome -wide association meta -analysis of ... | null | 2018-02-14T00:00:00 | CC BY 4.0 | true | -6.680096 | 332 | others | generate | false | false | [
{
"claim": "The biological roles of the six magnesium-associated SNP instruments are not sufficiently described; add known functions, perhaps in a table.",
"category": "reproducibility/details",
"target": "presentation",
"specific": true
},
{
"claim": "The first sentence of the Discussion (p... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1065-z | 12916_2018_1065_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | The study is a two -sample Mendelian randomization study using summary GWAS data investigating whether serum magnesium levels may be causally associated with coronary artery disease (CAD). The investigators use IVW as the main MR method and various other di fferent statistical MR methods as sensitivity analyses. The ta... | null | 2018-03-23T00:00:00 | CC BY 4.0 | true | -7.673195 | 158 | others | generate | false | false | [
{
"claim": "Instrument strength is not reported for individual SNPs or collectively with I²GX for MR-Egger.",
"category": "reproducibility/details",
"target": "method",
"specific": true
},
{
"claim": "Stratified results are not provided for incident versus prevalent CAD, sex, or ancestry.",
... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1067-x | 12916_2018_1067_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | To the Authors: The manuscript entitled: "Zika vaccines and therapeutics: landscape analysis and challenges ahead" by Wilder -Smith et al. is authoritative, concise and well -written. The information and insights provided are of high importance to researchers and public health personnel involved in Zika virus therapeut... | null | 2018-01-03T00:00:00 | CC BY 4.0 | true | -7.317123 | 685 | others | generate | false | false | [
{
"claim": "Throughout the manuscript, use virus abbreviations YFV, JEV, and TBEV instead of YF, JE, and TBE, including in Table 2.",
"category": "typo/formatting",
"target": "presentation",
"specific": true
},
{
"claim": "Identify full strains for therapeutic and vaccine candidates; for exa... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1067-x | 12916_2018_1067_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | Well -written organized, and comprehensive synthesis of the current considerations and landscape for Zika vaccine development from a number of existing WHO reports available on the WHO and clnicaltrials.gov websites by a g roup of eminent authors who appear to have been involved in the series of WHO meetings that led t... | null | 2018-01-21T00:00:00 | CC BY 4.0 | true | -7.418696 | 405 | others | generate | false | false | [
{
"claim": "The review largely overlaps more expansive articles in the December 2017 Journal of Infectious Diseases supplement, raising a novelty concern.",
"category": "novelty",
"target": "claims",
"specific": true
},
{
"claim": "The ending paragraph only briefly addresses diagnostic limit... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1069-8 | 12916_2018_1069_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | Qi and coworkers introduce the concept of 'transient portal vein thrombosis' in patients with cirrhosis. This clini cal entity encompasses portal vein thrombosis that spontaneously clears without anticoagulant treatment. The authors suggest that if we would be able to predict which portal vein thrombi have a high chanc... | null | 2018-01-13T00:00:00 | CC BY 4.0 | true | -7.180692 | 378 | others | generate | false | false | [
{
"claim": "The paper does not clarify whether most cases of transient PVT are asymptomatic.",
"category": "clarity/presentation",
"target": "results",
"specific": true
},
{
"claim": "The paper does not address whether watchful waiting is appropriate for recurrent PVT after spontaneous clear... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1069-8 | 12916_2018_1069_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | This report described two interesting cases of transient portal vein thrombosis in patients with liver cirrho sis. The subsequent literature review is nicely written. | null | 2018-01-30T00:00:00 | CC BY 4.0 | true | -4.949185 | 27 | others | generate | false | false | [] |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1069-8 | 12916_2018_1069_ReviewerReport_V0_R3 | Reviewer 3 | null | null | null | The authors report on a subject of considerable clinical relevance, as the safety of anticoagulation for portal venous thrombosis occurring in a patient with underlying cirrhosis and definite bleeding risk is often problematic. Identification of those paients who may appropriately be managed, at least initially, withou... | null | 2018-03-25T00:00:00 | CC BY 4.0 | true | -7.010442 | 207 | others | generate | false | false | [
{
"claim": "The Conclusion does not clarify how to manage patients with recent portal vein thrombosis and thrombus extension who are not liver transplant candidates.",
"category": "clarity/presentation",
"target": "claims",
"specific": true
}
] |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1072-0 | 12916_2018_1072_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | Overview: This manuscript describes the incidence and characteristics of ED visits following induced abortion using a large nationally representative data set. The authors conclude that abortion -related ED visits are rare and that m ost ED visits include only observation. Major incidents (transfusion, surgery, or hosp... | null | 2018-03-06T00:00:00 | CC BY 4.0 | true | -7.734194 | 479 | others | generate | false | false | [
{
"claim": "The abstract should define “observation care only” and “major incident,” which lack standard meanings.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "The Methods should report how many states NEDS includes and what share of the US ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1072-0 | 12916_2018_1072_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | This is a very well -written, interesting study, and will be an important and useful contribution to the literature. I believe that it will also be a useful contribution for researchers and policymakers working in all related healthcare fields. I recommend this manuscript for publication with a few minor revisions. Bel... | null | 2018-02-27T00:00:00 | CC BY 4.0 | true | -7.784951 | 1,372 | others | generate | false | false | [
{
"claim": "The Introduction’s final sentence notes visit frequency but omits that the study also examines the characteristics of abortion-related ED visits.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "Methods do not explain how the approxi... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1075-x | 12916_2018_1075_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This study assessed long -term effects of an 18 -week exercise program (PACT Study) on levels of fatigue and physical activity four years after participation in the PACT study. At four years, ITT mixed linear effects modeling showed that Intervention partici pants reported significantly higher moderate -to-vigorous phy... | null | 2018-01-23T00:00:00 | CC BY 4.0 | true | -7.517701 | 439 | others | generate | false | false | [
{
"claim": "Page 6 contradicts itself about inviting original PACT dropouts, leaving eligibility and inclusion in the four-year sample unclear.",
"category": "clarity/presentation",
"target": "experiments",
"specific": true
},
{
"claim": "Participants who dropped out during PACT’s 18-week in... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1075-x | 12916_2018_1075_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | Summary of the study: This RCT study aimed to investiga te the long -term effects of an 18 -week exercise intervention started during adjuvant treatment including chemotherapy on the levels of fatigue and physical activity evaluated 4 years later. The research is an extension of a previously published RCT entitle d Phy... | null | 2018-03-25T00:00:00 | CC BY 4.0 | true | -7.901011 | 1,002 | others | generate | false | false | [
{
"claim": "The statistically significant effect may not be true or clinically meaningful given its small size, assessment accuracy, and the study’s limitations.",
"category": "unsupported-claim",
"target": "claims",
"specific": false
},
{
"claim": "Differential selection or reporting at the... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1076-9 | 12916_2018_1076_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This is a very well written and extremely nicely conceptualised paper. It represents five years of work and thoughtful reflection on 22 projects categorizable either as translational researc h or implementation science. The authors have positioned the paper in an able way. The comments which follow are meant to help th... | null | 2018-02-27T00:00:00 | CC BY 4.0 | true | -7.420455 | 818 | others | generate | false | false | [
{
"claim": "Reducing complexity to simple rules risks losing the broader picture that complexity science is intended to capture.",
"category": "theory/correctness",
"target": "claims",
"specific": false
},
{
"claim": "Normative advice such as “embrace complexity,” including the principle on ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1076-9 | 12916_2018_1076_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | Summary This paper draws on documentary analysis, existing literature review, and observations of from 22 evidence translation projects (UK) to developed 12 'simple rules' for evidence translation and improvement, grouped under three themes to provide a guiding framework (SHIFT -Evidence) - 'Act Scientifically and prag... | null | 2018-03-04T00:00:00 | CC BY 4.0 | true | -7.250598 | 909 | others | generate | false | false | [
{
"claim": "The analysis is called grounded theory, but the paper does not justify that label or distinguish it from a constant comparative approach.",
"category": "reproducibility/details",
"target": "method",
"specific": true
},
{
"claim": "The literature review lacks detail on its method ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1076-9 | 12916_2018_1076_ReviewerReport_V0_R3 | Reviewer 3 | null | null | null | This is a landmark paper in the field of understanding how people bring about change processes taking complexity into account. It is beautifully written, well researched and performs the function of making comple xity navigable (but not simple). This is a feat. It also comes with the authority of intense fieldwork in 2... | null | 2018-03-08T00:00:00 | CC BY 4.0 | true | -7.507649 | 625 | others | generate | false | false | [
{
"claim": "The paper repeats material and summaries that could be shortened to make room for more content.",
"category": "clarity/presentation",
"target": "presentation",
"specific": false
},
{
"claim": "The supplementary files do not adequately explain how data from the 22 QI projects were... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1077-8 | 12916_2018_1077_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This study analysed pregnancy rates and neonatal outcome after frozen embryo transfer of intact embryos and embryos with up to 50% blastomeres damaged. The research question is certainly valid, most papers only describe up to implantation rates and the fact that this is a large -scale study makes it more valuable. Howe... | null | 2018-03-08T00:00:00 | CC BY 4.0 | true | -7.580719 | 314 | others | generate | false | false | [
{
"claim": "The manuscript needs thorough English grammar editing before publication.",
"category": "clarity/presentation",
"target": "presentation",
"specific": false
},
{
"claim": "The paper uses “cycles” where it appears to mean transfers; use “transfer” or “transfer cycle” for included F... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1077-8 | 12916_2018_1077_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | The objective of this study was to compare the pregnancy outcomes as a result of the transfer of intact thawed or warmed cleavage stage embryos vs embryos with blastomere loss as a result of cryopreservation. A total of 12,105 cycles were included in the analysis (9,846 cycles in intact embryo group and 2,259 cycles in... | null | 2018-04-02T00:00:00 | CC BY 4.0 | true | -7.341002 | 593 | others | generate | false | false | [
{
"claim": "It is unclear whether the study was prospective or retrospective and whether patients consented before FET.",
"category": "reproducibility/details",
"target": "experiments",
"specific": true
},
{
"claim": "The recommendation to transfer more than one blastomere-loss embryo is que... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1078-7 | 12916_2018_1078_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This is a very interesting study which intends to standardize approaches to judge the appropriateness of polypharmacy. The authors apply a systematic review of the literature to identify existing approaches, and then use a two -stage RAND/ UCLA Appropriateness Method involving 10 clinical experts to reach a consensus a... | null | 2018-02-20T00:00:00 | CC BY 4.0 | true | -7.536246 | 456 | others | generate | false | false | [
{
"claim": "Methods report the systematic review search as continuing “until the present day” without giving its exact end date.",
"category": "reproducibility/details",
"target": "method",
"specific": true
},
{
"claim": "The Methods do not explain how patient representatives were recruited.... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1078-7 | 12916_2018_1078_ReviewerReport_V0_R3 | Reviewer 3 | null | null | null | The authors of this study conducted a systematic review of inappropriate prescribing indicators followed by a consensus study to develop a usable meas ure of polypharmacy appropriateness. Overall this is a timely and well -conducted study, with very important outputs. This study (particularly the expert consensus proce... | null | 2018-02-06T00:00:00 | CC BY 4.0 | true | -7.452244 | 1,001 | others | generate | false | false | [
{
"claim": "The manuscript uses “systematic literature review” instead of the preferred term “systematic review.”",
"category": "clarity/presentation",
"target": "presentation",
"specific": false
},
{
"claim": "The Abstract omits the PROSPERO registration number.",
"category": "reproduci... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1081-z | 12916_2018_1081_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | Overall, this was an interesting paper presenting a wealth of historical information ab out the malaria situation at the border of Yemen and Saudi Arabia. Is there an opportunity to provide a continuous thread throughout the narrative or broaden the audience by articulating a larger aim? For instance, the "Regional imp... | null | 2018-03-27T00:00:00 | CC BY 4.0 | true | -7.364754 | 482 | others | generate | false | false | [
{
"claim": "The narrative lacks a continuous thread and an explicit larger aim linking its historical detail to border-malaria elimination planning.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "The text does not identify Saudi Arabia’s 2015 ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1081-z | 12916_2018_1081_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | Major comments This is an interesting paper on the potential impact of cross -border movement and economic development on malaria elimination in the Kingdom of Saudi Arabia. Overall however, it reads quite heavy on the historical aspects of the border, the conflict with Yemen and how the two affected provinces in Saudi... | null | 2018-03-28T00:00:00 | CC BY 4.0 | true | -7.920063 | 765 | others | generate | false | false | [
{
"claim": "The historical/conflict narrative outweighs the Jazan/Aseer malaria-incidence evidence, leaving conclusions about cross-border movement and economic development insufficiently supported.",
"category": "unsupported-claim",
"target": "claims",
"specific": true
},
{
"claim": "The ti... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1084-9 | 12916_2018_1084_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | This is a prospective study, carried out in a large cohort of Chinese adults, which faces the still unanswered question regarding the potential role of chronic Hepatitis B Virus (HBV) infection as a risk factor for Chronic Kidney Disease (CKD). The main results were that HBV infection is an independent risk factor for ... | null | 2018-01-03T00:00:00 | CC BY 4.0 | true | -7.207803 | 332 | others | generate | false | false | [
{
"claim": "Excluding baseline CKD based on self-report may miss undiagnosed early-stage cases, undercount baseline CKD, and inflate estimated CKD incidence during follow-up.",
"category": "statistical-rigor",
"target": "experiments",
"specific": true
},
{
"claim": "The tables should report ... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1084-9 | 12916_2018_1084_ReviewerReport_V0_R2 | Reviewer 2 | null | null | null | General comments: The authors report on the development of CKD on almost half a million patients, according to HBsAg status. Given the number of participants involved, it would seem that the investigators could examine a number of potential associations; however, they seem to leave out some potentially important variab... | null | 2018-02-27T00:00:00 | CC BY 4.0 | true | -6.859888 | 970 | meta_llama | generate | false | false | [
{
"claim": "The Abstract and Introduction do not clearly define CKD or specify its stages or GFR criteria.",
"category": "clarity/presentation",
"target": "presentation",
"specific": true
},
{
"claim": "The Abstract does not explain how CKD was ascertained.",
"category": "reproducibility... |
BMC-Med | journal | BMC Medicine | medicine | 2,018 | 10.1186/s12916-018-1087-6 | 12916_2018_1087_ReviewerReport_V0_R1 | Reviewer 1 | null | null | null | In the manuscript "Being pragmatic about healthcare complexity: our experiences applying complexity theory and pragmatism to health services research' the authors address the complexity of healthcare sector, and relate this to chal lenges for implementation and evaluation. They set out characteristics of Complex Adapti... | null | 2018-03-19T00:00:00 | CC BY 4.0 | true | -7.865148 | 779 | others | generate | false | false | [
{
"claim": "Simulation modeling is highlighted in the abstract but receives little attention in the manuscript.",
"category": "experiments-scope",
"target": "experiments",
"specific": true
},
{
"claim": "The exemplar does not clearly identify the intervention, the simulation models, or the p... |
Twice-Told Critiques
Peer reviews from three ML conferences and five open-review journal sources, with claims extracted by an LLM, problem groups for each paper's reviews, and MELD scores for LLM-generated text. This is the data of the paper "Twice-Told Critiques: Claim-Level Homogenization of Peer Review in the LLM Era". Code: https://github.com/anonresearch01/twicetold.
400,346 reviews, 121,938 papers, 141,769 panels.
Sources
| source | years | papers | reviews | in_sample | with_claims | with_meld |
|---|---|---|---|---|---|---|
| BMC-Med | 2018–2025 | 2,688 | 6,870 | 6,856 | 6,869 | 6,870 |
| Copernicus | 2018–2026 | 18,000 | 39,326 | 39,306 | 39,310 | 39,326 |
| F1000 | 2018–2026 | 7,598 | 18,192 | 18,172 | 18,175 | 18,192 |
| ICLR | 2017–2026 | 47,872 | 182,801 | 164,539 | 168,429 | 164,534 |
| ICML | 2025–2026 | 9,598 | 36,856 | 36,804 | 36,804 | 36,804 |
| NeurIPS | 2021–2025 | 18,751 | 75,201 | 74,866 | 74,866 | 74,866 |
| PLOS | 2019–2026 | 14,360 | 34,240 | 34,084 | 34,118 | 34,240 |
| SciPost | 2018–2026 | 3,072 | 6,860 | 6,859 | 6,860 | 6,860 |
in_sample: the review is in the analysis sample (at most 5 reviews per paper, sampled papers only).with_claims: the review has extracted claims.with_meld: the review has a MELD score.
Conference reviews: ICLR and NeurIPS from OpenReview via ResearchArcade and iclr-2026; ICML 2025–2026 accepted papers from the OpenReview API. Journal reports: SciPost (API); F1000Research, Wellcome Open Research, Open Research Europe and PLOS (Europe PMC); BMC Medicine (JerMa88/BMC_Medicine_Peer_Reviews); Copernicus/EGU (journal discussion pages). Journal samples hold up to 2,000 papers per source-year, first-round reports only.
Configs
reviews
One row per review. One file per source.
| Column | Meaning |
|---|---|
source |
ICLR, NeurIPS, ICML, BMC-Med, Copernicus, F1000, PLOS, SciPost |
venue_type |
conference or journal |
journal, field |
Journal name and field |
year, paper_id, review_id |
Source year and source ids |
reviewer |
Anonymous label such as Reviewer 2 or Reviewer_8LjP; null when the source gives none |
rating, rating_raw |
Numeric rating where the source has one, and the source label |
confidence |
Reviewer confidence (conferences) |
text |
Review text; conference form fields are joined with [FIELD] headers |
form |
Conference review form fields |
review_time |
Review date (UTC) |
licence |
Licence of the text |
in_sample |
The review is in the analysis sample |
claims |
Extracted claims: list of {claim, category, target, specific}; empty list when the review has no critique; null when not extracted |
meld_score |
MELD score: mean of the top token scores |
meld_tokens |
Number of scored tokens |
meld_family, meld_task |
MELD's most likely LLM family and operation (for example generate or polish) |
meld_flag |
meld_score is above the threshold |
meld_written |
meld_flag and meld_task == "generate" |
papers
One row per paper with at least one review in reviews: title, abstract (conferences), decision, withdrawn
status, OpenReview primary area, predicted area (area_pred, ICLR and NeurIPS sample papers), licence and number of
reviews.
panels
One row per panel: a set of reviews whose claims the LLM grouped into shared problems.
| kind | panels |
|---|---|
| placebo_area | 2,996 |
| placebo_venue | 4,500 |
| journal_placebo | 6,450 |
| journal | 45,703 |
| icml | 9,588 |
| subset3 | 9,513 |
| withdrawn | 1,000 |
| paper | 62,019 |
paper: the reviews of one ICLR or NeurIPS paper (main analysis).icml,journal: the reviews of one ICML or journal paper.subset3: three-review subsets of papers with at least four reviews.withdrawn: reviews of withdrawn ICLR 2026 papers.placebo_venue,placebo_area,journal_placebo: one review each from different papers of one venue-year (or one predicted area-year). Overlap here measures matches that do not come from a shared paper.
Columns: panel_id, kind, review_ids, targets (list of {target_id, element}) and clusters (list of
{target_id, problem, claim_ids}). A claim id R{i}-{j} is claim j of review review_ids[i], in the order of
the claims column.
Extraction
Model: gpt-6-luna-high (OpenRouter route openai/gpt-6-luna), reasoning effort high for claims and
high for grouping. Prompts: src/prompts/pass1.j2 and src/prompts/pass2.j2 in the code repository.
The model sees each review in full.
MELD
Detector: anon-review-meld-2026/meld, revision ddfc9c789b8c8d0f92d3774265316d418c96dc67. Threshold
2.7450: the 0.999 quantile of scores on 110,080 reviews from 2022 and
earlier. So about 0.1% of human-written reviews carry meld_flag. A flag is a detector output, not proof that a
reviewer used an LLM. Do not use it to judge an individual reviewer.
Licence
Each row carries its licence. Journal reports keep their CC BY or CC0 terms. Conference reviews are public OpenReview reviews; follow OpenReview's terms. Extracted claims, panels and MELD scores: CC BY 4.0.
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