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22,500
The CHA<sub>2</sub>DS<sub>2</sub>-VASc Score Predicts New-Onset Atrial Fibrillation and Hemodynamic Complications in Patients with ST-Segment Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention.
Arrhythmic and hemodynamic complications related to ST-segment elevation myocardial infarction (STEMI) represent a major clinical challenge. Several scores have been developed to predict mortality in STEMI. However, those scores almost exclusively include factors related to the acute phase of STEMI, and no score has be...
22,501
The Role of Hypomagnesemia in Cardiac Arrhythmias: A Clinical Perspective.
The importance of magnesium (Mg<sup>2+</sup>), a micronutrient implicated in maintaining and establishing a normal heart rhythm, is still controversial. It is known that magnesium is the cofactor of 600 and the activator of another 200 enzymatic reactions in the human organism. Hypomagnesemia can be linked to many fact...
22,502
In-hospital cardiac arrest rhythm analysis by anesthesiologists: a diagnostic performance study.
R&#xe9;SUM&#xe9;: OBJECTIF: L&#x2019;arr&#xea;t cardiaque intra-hospitalier est associ&#xe9; &#xe0; une morbidit&#xe9; et mortalit&#xe9; &#xe9;lev&#xe9;es, associ&#xe9;es &#xe0; un taux de survie global &#xe0; un an d&#x2019;environ 13&#xa0;%. Le premier rythme cardiaque est souvent analys&#xe9; par des anesth&#xe9;sio...
22,503
[History and perspectives of the defibrillation].
History of the discovery of fibrillation and defibrillation, stages of the development of the concept of defibrillation are described in the article. The differences in mechanisms of different types of defibrillation are given here. The modern state of defibrillation and future trends are discussed in our article.</Abs...
22,504
[Efficiency and safety of using the modified protocol for the administration of the domestic class III antiarrhythmic drug for the relief of paroxysmal atrial fibrillation].
&#x426;&#x435;&#x43b;&#x44c;. &#x41e;&#x446;&#x435;&#x43d;&#x43a;&#x430; &#x44d;&#x444;&#x444;&#x435;&#x43a;&#x442;&#x438;&#x432;&#x43d;&#x43e;&#x441;&#x442;&#x438; &#x438; &#x431;&#x435;&#x437;&#x43e;&#x43f;&#x430;&#x441;&#x43d;&#x43e;&#x441;&#x442;&#x438; &#x43f;&#x440;&#x438;&#x43c;&#x435;&#x43d;&#x435;&#x43d;&#x438...
22,505
[Dynamics of Holter electrocardiogram monitoring in patients with chronic heart failure and atrial fibrillation on the background of cardiac contractility modulation].
&#x426;&#x435;&#x43b;&#x44c;. &#x41e;&#x446;&#x435;&#x43d;&#x438;&#x442;&#x44c; &#x434;&#x438;&#x43d;&#x430;&#x43c;&#x438;&#x43a;&#x443; &#x43d;&#x430;&#x440;&#x443;&#x448;&#x435;&#x43d;&#x438;&#x439; &#x440;&#x438;&#x442;&#x43c;&#x430; &#x441;&#x435;&#x440;&#x434;&#x446;&#x430; &#x43d;&#x430; &#x444;&#x43e;&#x43d;&#x4...
22,506
[Predictive value of <i>QRS</i> complex duration in patients with chronic heart failure and atrial fibrillation: retrospective study].
&#x426;&#x435;&#x43b;&#x44c;. &#x418;&#x437;&#x443;&#x447;&#x438;&#x442;&#x44c; &#x43e;&#x441;&#x43e;&#x431;&#x435;&#x43d;&#x43d;&#x43e;&#x441;&#x442;&#x438; &#x442;&#x435;&#x447;&#x435;&#x43d;&#x438;&#x44f; &#x437;&#x430;&#x431;&#x43e;&#x43b;&#x435;&#x432;&#x430;&#x43d;&#x438;&#x44f; &#x438; &#x43f;&#x440;&#x43e;&#x43...
22,507
[The effectiveness of cardiac contractility modulation in patients with chronic heart failure and atrial fibrillation: results of the 12-month follow-up].
&#x426;&#x435;&#x43b;&#x44c;. &#x41e;&#x446;&#x435;&#x43d;&#x438;&#x442;&#x44c; &#x44d;&#x444;&#x444;&#x435;&#x43a;&#x442;&#x438;&#x432;&#x43d;&#x43e;&#x441;&#x442;&#x44c;, &#x431;&#x435;&#x437;&#x43e;&#x43f;&#x430;&#x441;&#x43d;&#x43e;&#x441;&#x442;&#x44c; &#x438; &#x432;&#x43b;&#x438;&#x44f;&#x43d;&#x438;&#x435; &#x4...
22,508
[Features of vectorcardiograms in patients with hypertension complicated by chronic heart failure with reduced left ventricle ejection fraction].
&#x426;&#x435;&#x43b;&#x44c;. &#x418;&#x437;&#x443;&#x447;&#x438;&#x442;&#x44c; &#x43e;&#x441;&#x43e;&#x431;&#x435;&#x43d;&#x43d;&#x43e;&#x441;&#x442;&#x438; &#x432;&#x435;&#x43a;&#x442;&#x43e;&#x440;&#x43a;&#x430;&#x440;&#x434;&#x438;&#x43e;&#x433;&#x440;&#x430;&#x43c;&#x43c; (&#x412;&#x41a;&#x413;) &#x443; &#x431;&#x...
22,509
[Myocardial remodeling in patients with chronic heart failure and implanted cardiac contractility modulators].
&#x426;&#x435;&#x43b;&#x44c;. &#x418;&#x437;&#x443;&#x447;&#x438;&#x442;&#x44c; &#x432;&#x43b;&#x438;&#x44f;&#x43d;&#x438;&#x435; &#x43c;&#x43e;&#x434;&#x443;&#x43b;&#x44f;&#x446;&#x438;&#x438; &#x441;&#x435;&#x440;&#x434;&#x435;&#x447;&#x43d;&#x43e;&#x439; &#x441;&#x43e;&#x43a;&#x440;&#x430;&#x442;&#x438;&#x43c;&#x43e...
22,510
May Strenuous Endurance Sports Activity Damage the Cardiovascular System of Healthy Athletes? A Narrative Review.
The positive effects of physical activity are countless, not only on the cardiovascular system but on health in general. However, some studies suggest a U-shape relationship between exercise volume and effects on the cardiovascular system. On the basis of this perspective, moderate-dose exercise would be beneficial com...
22,511
Feasibility of Left Bundle Branch Area Pacing Combined with Atrioventricular Node Ablation in Atrial Fibrillation Patients with Heart Failure.
Pacemaker implantation combined with atrioventricular node ablation (AVNA) could be a practical choice for atrial fibrillation (AF) patients with heart failure (HF). Left bundle branch area pacing (LBBaP) has been widely reported.</AbstractText>To explore the safety and efficacy of LBBaP combined with AVNA in AF patien...
22,512
Short-Term Atrioventricular Dysfunction Recovery after Post-TAVI Pacemaker Implantation.
Permanent pacemaker implantation (PPI) represents a frequent complication after transcatheter aortic valve implantation (TAVI) due to atrio-ventricular (AV) node injury. Predictors of early AV function recovery were investigated. We analyzed 50 consecutive patients (82 &#xb1; 6 years, 58% males, EuroSCORE: 7.8 &#xb1; 3...
22,513
Analysis of Early Warning Diagnostic Indexes and Influencing Factors of Anxiety and Depression in Patients with Arrhythmia.
Arrhythmia patients complicated with psychological problems are very common in clinics. The imbalance of autonomic nervous regulation of the heart caused by anxiety and depression will further promote the occurrence and development of arrhythmia. For nonorganic heart disease, &#x3b2;</i> receptor blockers combined with...
22,514
[Warto&#x15b;&#x107; prognostyczna wska&#x17a;nik&#xf3;w elektrokardiograficznych zawa&#x142;u prawej komory w ocenie wewn&#x105;trzszpitalnego przebiegu klinicznego u chorych z rozpoznanym zawa&#x142;em &#x15b;ciany dolnej leczonych interwencyjnie].
Myocardial infarction (MI) of the right ventricle (RV) coexists in 20- 60% of patients with inferior MI. There are electrocardiographic indicators which are connected with RV MI, which may also predict unfavorable clinical outcome of in-hospital follow-up.</AbstractText>The aim of the study was determination a value of...
22,515
Association between sodium-glucose cotransporter-2 inhibitors and incident atrial fibrillation/atrial flutter in heart failure patients with reduced ejection fraction: a meta-analysis of randomized controlled trials.
Atrial fibrillation (AF) and atrial flutter (AFL) are associated with adverse outcomes in patients with heart failure and reduced ejection fraction (HFrEF). We investigated the effects of sodium-glucose cotransporter-2 inhibitors (SGLT2i) on the incidence of AF and/or AFL in HFrEF patients. PubMed and ClinicalTrials.go...
22,516
Vernakalant for Cardioversion of Recent-Onset Atrial Fibrillation in the Emergency Department: The SPECTRUM Study.
Intravenous vernakalant is a therapeutic option for symptomatic, recent-onset atrial fibrillation (AF). This secondary analysis from the large SPECTRUM study assessed the safety and effectiveness of vernakalant when used in the emergency department setting (ED group) or in an inpatient hospital setting (non-ED group).<...
22,517
The impact of atrial fibrillation and atrial tachycardias on the hemodynamic status of patients with pulmonary hypertension.
The impact of atrial fibrillation and atrial tachycardias (AF/AT), and their optimal treatment strategy in PH patients is still being discussed. The goal of this study was to evaluate the effect of AF/AT termination on the hemodynamic parameters in PH patients. We compared patients with pre-capillary pulmonary hyperten...
22,518
Development of a clinical decision rule for the early prediction of Shock-Refractory Out-of-Hospital cardiac arrest.
Nearly half of ventricular fibrillation or ventricular tachycardia (VF/VT) out-of-hospital cardiac arrest (OHCA) patients receive three or more shocks, often referred to as refractory VF/VT. Our objective was to derive a clinical decision rule (CDR) for the early stratification of patients into risk categories for refr...
22,519
Clinical characteristics of patients with heart failure and intracardiac thrombus.
Heart failure (HF) patients are in a hypercoagulable state that predisposes them to an intracardiac thrombus. We aim to assess the clinical features of patients with HF and intracardiac thrombus.</AbstractText>Patients diagnosed with HF with intracardiac thrombus were enrolled in this study. Patients' demographics, cli...
22,520
Current Status of Transcatheter Tricuspid Valve Therapies.
Tricuspid regurgitation is a complex disease that carries a poor prognosis, and surgical repair is associated with high mortality. In light of the success of other transcatheter-based valve interventions, transcatheter tricuspid therapy has recently seen exponential use both clinically and in innovation. Given the rapi...
22,521
Rapid Atrial Fibrillation in the Emergency Department.
Atrial fibrillation (AF) is the most common rhythm disorder seen in doctors' offices and emergency departments (EDs). In both settings, an AF holistic pathway including anticoagulation or stroke avoidance, better symptom management, and cardiovascular and comorbidity optimization should be followed. However, other cons...
22,522
Feasibility and safety of three-dimensional electroanatomical cardiac mapping, mapping-guided biopsy and transseptal puncture in dogs.<Pagination><StartPage>23</StartPage><EndPage>37</EndPage><MedlinePgn>23-37</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jvc.2022.09.002</ELocationID><ELocat...
Three-dimensional electroanatomical mapping (3D EAM) has expanded radiofrequency catheter ablation applications in humans to almost all complex arrhythmias and has drastically reduced fluoroscopy use, yet its potential in dogs is poorly investigated. The objectives of the current study were to assess the feasibility an...
22,523
Interplay between cardiovascular and thyroid dysfunctions: A review of clinical implications and management strategies.
Cardiovascular diseases (CVD) and thyroid dysfunction are two of the most prevailing disorders in the world that are closely interlinked. Actions of thyroid hormones are mediated via thyroid receptors present in the myocardium and the vascular tissue. Primary mechanism that links thyroid dysfunction with CVD is the mod...
22,524
An Electrical Storm Is Coming!: Ventricular Storm Case Study.
A 65-year-old man presented to the emergency department (ED) for evaluation of epigastric and chest pain. On presentation, a 12-lead electrocardiogram revealed a patient in rapid atrial fibrillation (AFib) with anteroseptal myocardial infarction. Treatment of ST-elevation myocardial infarction (STEMI) and rapid AFib we...
22,525
New onset atrial fibrillation during orthotopic liver transplantation induced by iced saline injection for transpulmonary thermodilution: a case report.
Transpulmonary thermodilution is often used to measure extravascular lung water during liver transplantation. Here, the case of new onset atrial fibrillation during orthotopic liver transplantation, which may have been induced by iced saline injection for transpulmonary thermodilution measurement, is described. A 52-ye...
22,526
Anterior wall STEMI in a patient with paroxysmal atrial fibrillation due to coronary embolism: A case report.
Coronary embolism (CE) is a rare cause of acute ST-elevation myocardial infarction (STEMI). Atrial fibrillation (AF), left ventricular thrombus, septic emboli from infective endocarditis, myxoma, and paradoxical embolism can induce emboli in coronary arteries.</AbstractText>Here we present a case of anterior wall STEMI...
22,527
Implantable loop recorder in unexplained palpitations or syncope: A randomised study among young patients with structurally normal heart.
The utility of an implantable loop recorder (ILR) in the evaluation of unexplained syncope or palpitations in young patients in the absence of structural heart disease or ventricular dysfunction is limited. To compare the diagnostic yield of ILR with conventional extended Holter evaluation in the detection of arrhythmi...
22,528
A case report of arrhythmogenic mitral valve disease: still a long way to go.
Mitral valve prolapse (MVP) is a common valvular heart disease and has often been associated with an increased risk of sudden cardiac death (SCD). This underlines the pressing need for the establishment of consistent tools for arrhythmic risk prediction.</AbstractText>A 73-year-old man with previous diagnosis of MVP wa...
22,529
Spontaneous Coronary Artery Dissection: Chest Pain in a Young Woman.
We present two cases of spontaneous coronary artery dissection (SCAD). Both examples encourage a broad differential and open mind for chest pain in a young woman. We also highlight a case of SCAD where the patient presented following ventricular fibrillation arrest, a less common though potentially fatal consequence of...
22,530
An overview of mineralocorticoid receptor antagonists as a treatment option for patients with heart failure: the current state-of-the-art and future outlook.
Mineralocorticoid receptor antagonists (MRAs) improve cardiovascular outcomes in patients with heart failure. These benefits of MRAs vary in different heart failure populations based on left ventricular ejection fraction and associated comorbidities.</AbstractText>We define the pharmacologic properties of MRAs and the ...
22,531
Worsening Heart Failure and Atrial Flutter in a Patient Secondary to Cardiac Resynchronization Therapy Dyssynchrony: A Case Report.
Cardiac resynchronization therapy-defibrillator (CRT-D) and/or cardiac resynchronization therapy-pacemaker (CRT-P) play an important role in improving cardiac synchronization and reducing the risk of ventricular fibrillation arrest (VFA) in patients with severe left ventricular systolic dysfunction (LVSD). Patients wit...
22,532
Total Hip Replacement Interrupted by Intraoperative Arrest with a Final Component in Place: A Case Report.
No consensus recommendations exist as to the management of implants exposed during an interrupted total hip arthroplasty (THA). Given the infrequency of such events, documentation of successful outcomes in single case reports aids in decision-making. A 71-year-old male with a history of coronary artery disease and a BM...
22,533
Efficacy and Safety of Sustained-Release Metoprolol With Dronedarone After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation: A Propensity Matched Analysis.
The high early recurrence (ER) rate after radiofrequency catheter ablation (RFCA) seriously affects the prognosis of patients with atrial fibrillation (AF), and there are still controversies regarding the best preventive drugs for postoperative recurrence. A single-center retrospective study was conducted on patients w...
22,534
VENTRI&#x421;ULAR ECTOPIC ACTIVITY - A PREDICTOR OF SUDDEN CARDIAC DEATH IN PATIENTS WITH ATRIAL FIBRILLATION AND POST-INFARCTION LEFT VENTRICULAR ANEURISMS.
The article presents a clinical case of a patient who died suddenly from a rapid transformation of ventricular extrasystole into high-grade ectopy during persistent atrial fibrillation. All electrical events preceding death were recorded by the Holter monitor, which the patient was wearing at the time. It was revealed ...
22,535
Hepatic T1-Time Predicts Cardiovascular Risk in All-Comers Referred for Cardiovascular Magnetic Resonance: A Post-Hoc Analysis.
Liver damage is frequently observed in patients with cardiovascular disease but infrequently quantified. We hypothesized that in patients with cardiovascular disease undergoing cardiac magnetic resonance, liver T1-times indicate liver damage and are associated with cardiovascular outcome.</AbstractText>We measured hepa...
22,536
Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry.
To describe the natural history of SARS-CoV-2 infection in patients with hypertrophic cardiomyopathy (HCM) compared with a control group and to identify predictors of adverse events.</AbstractText>Three hundred and five patients [age 56.6&#xa0;&#xb1;&#xa0;16.9&#xa0;years old, 191 (62.6%) male patients] with HCM and SAR...
22,537
Post-cardiopulmonary bypass longitudinal strain provides higher prognostic ability than baseline strain or change in strain.
Global longitudinal strain (GLS) measured by speckle-tracking echocardiography demonstrates excellent prognostic ability in predicting major adverse cardiac events after cardiac surgery. However, the optimal timing of intraoperative GLS measurement that provides the best prognostic value is unclear.</AbstractText>Our g...
22,538
Benefits of support groups for patients living with implantable cardioverter defibrillators: a mixed-methods systematic review and meta-analysis.
Patients with implantable cardioverter defibrillators (ICD) experience anxiety, depression and reduced quality of life (QoL).</AbstractText>This mixed-methods systematic review evaluates whether ICD support groups have a beneficial effect on mental well-being.</AbstractText>Literature searches were carried out in MEDLI...
22,539
The monoacylglycerol lipase inhibitor, JZL184, has comparable effects to therapeutic hypothermia, attenuating global cerebral injury in a rat model of cardiac arrest.
Post-resuscitation cerebral ischemia-reperfusion injury (IRI) is a vital contributor to poor neurological prognosis. Exploring novel therapeutics that attenuate cerebral IRI is of great significance. Inflammation plays a role in the development of cerebral IRI after successful cardiopulmonary resuscitation (CPR). Monoa...
22,540
Intravenous metoprolol versus diltiazem for atrial fibrillation with concomitant heart failure.
Atrial fibrillation (Afib) with rapid ventricular response (RVR) is acutely treated with intravenous push (IVP) metoprolol (MET) or diltiazem (DIL). In heart failure (HF) patients, diltiazem is not recommended due to negative inotropic effects. Studies comparing the treatment of atrial fibrillation often exclude HF. Hi...
22,541
Time in therapeutic range for virtual anticoagulation clinic versus in-person clinic during the COVID-19 pandemic: a crossover study.
COVID-19 infection affects the quality of the medical services globally. The pandemic required changes to medical services in several institutions. We established a virtual clinic for anticoagulation management during the pandemic using the Whatsapp application.</AbstractText>Compare anticoagulation management quality ...
22,542
Prognostic Implications of Exercise-Induced Hypertension in Adults With Repaired Coarctation of Aorta.
The purpose of this study was to assess the relationship between exercise-induced hypertension (EIH) and cardiovascular events, and to determine whether exercise blood pressure (BP) improved risk stratification in adults with repaired coarctation of aorta.</AbstractText>Retrospective study of patients with repaired coa...
22,543
Electrocution&#xa0;- post-mortem presentations, problems and pitfalls.
Deaths due to electrocution occur when there has been passage of an electric current through the body. Lethal mechanisms may involve the heart with ventricular fibrillation, or the respiratory muscles or brainstem respiratory centres with respiratory paralysis/cessation. The size of the current that flows through the b...
22,544
Right ventricular dysfunction in patients with new-onset heart failure: longitudinal follow-up during guideline-directed medical therapy.
Improvement in left ventricular ejection fraction (LVEF) after up-titration of guideline-directed medical therapy (GDMT) has been well described in heart failure (HF) patients. Less is known about the prevalence and clinical course of right ventricular dysfunction (RVD) in patients with new-onset HF.</AbstractText>From...
22,545
The first case series analysis on efficacy of esmolol injection for in-hospital cardiac arrest patients with refractory shockable rhythms in China.
<b>Background:</b> This study assessed the effects of esmolol injection in patients with in-hospital cardiac arrest (IHCA) with refractory ventricular fibrillation (VF)/pulseless ventricular tachycardia (pVT). <b>Methods:</b> From January 2018 to December 2021, 29 patients with IHCA with refractory shockable rhythm wer...
22,546
Efficacy of Exercise Rehabilitation in Patients with Atrial Fibrillation after Radiofrequency Ablation: A Meta-Analysis of Randomized Controlled Trials.
Radiofrequency ablation is a commonly used treatment for paroxysmal atrial fibrillation (AF), but postoperative rehabilitation exercises are needed to reverse left ventricular structural and functional abnormalities. This meta-analysis aimed to evaluate the intervention effect of exercise training in patients with AF a...
22,547
Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest.
Post-cardiac arrest (CA) brain injury is the main cause of death in patients resuscitated from CA. Previous studies demonstrated that hydrogen inhalation mitigates post-CA brain injury. However, factors affecting the efficacy of hydrogen remain unknown. In the present study, we investigated the influence of oxygen conc...
22,548
Overdrive pacing in the acute management of osimertinib-induced ventricular arrhythmias: A case report and literature review.
QT interval prolongation and ventricular arrhythmias (VAs) induced by osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, are life-threatening complications. However, no consensus has been achieved regarding their management. Overdrive pacing has been shown to be effective in sho...
22,549
Catheter ablation in patients with ventricular fibrillation by purkinje de-networking.
Ventricular fibrillation (VF) is a leading cause of cardiovascular death worldwide. However, recurrence rates of arrhythmia are high leading to mortality and morbidity. Recently, Purkinje fibers have been identified as potential sources of VF initiation and maintenance.</AbstractText>The study analyzes the feasibility ...
22,550
Novel spatiotemporal processing tools for body-surface potential map signals for the prediction of catheter ablation outcome in persistent atrial fibrillation.
<b>Background:</b> Signal processing tools are required to efficiently analyze data collected in body-surface-potential map (BSPM) recordings. A limited number of such tools exist for studying persistent atrial fibrillation (persAF). We propose two novel, spatiotemporal indices for processing BSPM data and test their c...
22,551
Left atrial appendage occlusion in ventricular assist device patients to decrease thromboembolic events: A computer simulation study.
Atrial fibrillation (AF) is a common comorbidity in left ventricular assist device (LVAD) patients and has been identified as a risk factor for thromboembolic stroke. Blood stagnation within the left atrial appendage (LAA) is considered a possible major source of thrombosis and clinical studies have shown reduced throm...
22,552
Normal pacing function with normal impedance trends despite evident lead fracture in an implantable defibrillator - What is the mechanism?
A 63-year-old lady with a high-grade atrioventricular (AV) block and a structurally normal heart underwent permanent pacemaker implantation (dual chamber, Medtronic Ltd) 8 years back. On follow up, she had a recurrence of syncope after 3 years. The device interrogation at that time had revealed ventricular tachycardia ...
22,553
Return to Flying After Catheter Ablation of Arrhythmic Disorders in Military Aircrew.
<b>INTRODUCTION:</b> Catheter ablation is a widely used and effective treatment option for many tachyarrhythmic disorders. This study analyzes all ablation cases in German military aircrew over a 17-yr period. Recurrence of different arrhythmias and ablation complications were analyzed with an aim of refining specific ...
22,554
Effect of Duration of Anticoagulation in the Incidence of Stroke in Patients With Left-Ventricular Thrombus.
The optimal duration of anticoagulation in patients with left-ventricular thrombus (LVT) is unclear. In the present study, we aimed to analyze the effect of treatment duration (&#x2264;12 months [short-term anticoagulation, (STA)] versus &gt;12 months [long-term anticoagulation, (LTA)]) in the incidence of stroke and o...
22,555
Infarct-related artery and long-term mortality following recurrent ST-segment elevation myocardial infarction. Insights from a Polish nationwide registry.
Recurrent ST-segment elevation myocardial infarction (rSTEMI) can be attributed to the same (target-vessel, TV-rSTEMI) or different culprit vessel (non-target, nonTV-rSTEMI) compared with the first infarction. We hypothesized that long-term mortality after rSTEMI depends on the infarct-related artery (the same or diffe...
22,556
What is the Best Agent for Rate Control of Atrial Fibrillation With Rapid Ventricular Response?
Atrial fibrillation (AF) is a common dysrhythmia associated with significant morbidity and mortality. Although many patients have stable AF, some patients can present with a rapid ventricular response (RVR). In these patients, it is important to lower their heart rate. However, there are several options available for r...
22,557
Protocol for a cluster randomised controlled feasibility study of Prehospital Optimal Shock Energy for Defibrillation (POSED).
The Prehospital Optimal Shock Energy for Defibrillation (POSED) study will assess the feasibility of conducting a cluster randomised controlled study of clinical effectiveness in UK ambulance services to identify the optimal shock energy for defibrillation.</AbstractText>POSED is a pragmatic, allocation concealed, open...
22,558
Evaluation of the pulmonary vein ostia during the cardiac cycle using electrocardiography-gated cardiac computed tomography in cats.
Several studies in humans have provided detailed descriptions of the anatomy of the pulmonary veins (PVs) and their ostia for the implementation of thoracic interventions, such as radiofrequency ablation, for patients with atrial fibrillation. These studies have shown that electrocardiography (ECG)-gated multidetector ...
22,559
In-hospital arrhythmic burden reduction in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: Insights from the SGLT2-I AMI PROTECT study.
Sodium-glucose co-transporter 2 inhibitors (SGLT2-i) have shown significant cardiovascular benefits in patients with and without type 2 diabetes mellitus (T2DM). They have also gained interest for their potential anti-arrhythmic role and their ability to reduce the occurrence of atrial fibrillation (AF) and ventricular...
22,560
Proarrhythmic effect of radiofrequency catheter ablation on the right ventricular moderator band.
Following ablation on the RV moderator band for suppression of monomorphic PVCs, recurrent VT and VF were triggered by the same PVC at shorter coupling intervals. This is likely a pro arrhythmic effect of ablation on the moderator band.
22,561
Para-Hisian pacing: The eyes see what the mind knows.
A young male presented with pre-excited atrial fibrillation. During an electrophysiology study, preexcitation suggestive of a pathway in posteroseptal location was confirmed but no tachycardia was inducible. Para-Hisian pacing was done during sinus rhythm. Is there retrograde conduction through the accessory pathway?
22,562
Cardiac resynchronization therapy in the presence of total atrioventricular block reduces long-lasting atrial fibrillation episodes.
There is an ongoing debate on how cardiac resynchronization therapy (CRT) in the presence of total AV block affects atrial fibrillation (AF) episodes and symptoms in patients with AF.</AbstractText>Seventy-five patients with symptomatic, drug and ablation refractory AF received, irrespective of their left ventricular e...
22,563
Tachycardia-Induced Cardiomyopathy in a Young Healthy Patient: A Case Report.
Tachycardia-induced cardiomyopathy (TIC) can result in both systolic and/or diastolic ventricular dysfunction as a result of the prolonged fast heart rate which is reversible upon controlling the fast heart rate or arrhythmia. The exact heart rate that can lead to this is not clear, however, a heart rate &gt; 100 in ge...
22,564
An 82-year-old man with a prosthetic aortic valve and multimicrobial bacteremia.
The patient is an 82-year-old male with a past medical history of aortic valve replacement who presented to the emergency department after a fall. He developed atrial fibrillation with a rapid ventricular response and non-ST-segment-elevation myocardial infarction, leading to hospitalization. During hospital admission,...
22,565
Cardiogenic shock due to Takotsubo cardiomyopathy associated with thyroid crisis: a case report.
The development of cardiogenic shock due to the coexistence of Takotsubo cardiomyopathy and thyroid crisis in patients has been scarcely reported.</AbstractText>A 46-year-old female presented with chest pain, palpitations, nausea, and vomiting for 8&#x2005;h. She was initially considered to have acute myocardial infarc...
22,566
Left Ventricular Diastolic Indices and Their Impact on Outcomes in Patients with Recently Diagnosed Atrial Fibrillation.
Background: Early identification of atrial fibrillation (AF) patients at risk for heart failure (HF) remains critical for improving their outcomes. We aimed to investigate whether indices of left ventricular diastolic dysfunction (LVDD) can stratify AF patients without clinical history of HF. Methods: We extracted 1775...
22,567
Catheter Ablation versus Medical Therapy of Atrial Fibrillation in Patients with Heart Failure: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Background: Atrial fibrillation (AF) and heart failure (HF) often coexist and synergistically contribute to an increased risk of hospitalization, stroke, and mortality. Objective: To compare the efficacy of catheter ablation (CA) versus medical therapy (MT) in HF patients with AF. Methods: Electronic databases were que...
22,568
ECG Markers of Acute Melatonin Treatment in a Porcine Model of Acute Myocardial Ischemia.
In myocardial ischemia, melatonin confers antiarrhythmic action, but its electrocardiographic expression is unclear. We aimed to evaluate the effects of melatonin treatment on electrocardiogram (ECG) parameters reflecting major arrhythmogenic factors and to test the association of these parameters with ventricular fibr...
22,569
Left Atrial Myocardium in Arterial Hypertension.
Arterial hypertension affects &#x2248; 1 billion people worldwide. It is associated with increased morbidity and mortality and responsible for millions of deaths each year. Hypertension mediates damage of target organs including the heart. In addition to eliciting left ventricular hypertrophy, dysfunction and heart fai...
22,570
Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Na<sub>v</sub>1.5 downregulation and ventricular arrhythmias.
Abnormal myocardial Nav</sub>1.5 expression and function cause lethal ventricular arrhythmias during myocardial ischemia-reperfusion (I/R). Protein inhibitor of activated STAT Y (PIASy)-mediated caveolin-3 (Cav-3) SUMO modification affects Cav-3 binding to the voltage-gated sodium channel 1.5 (Nav</sub>1.5). PIASy acti...
22,571
Ventricular arrhythmias after fibroma resection: Are patients still at risk?
Ventricular fibromas frequently present with life-threatening ventricular tachycardia (VT) or ventricular fibrillation (VF) in children. The long-term risk of sustained ventricular arrhythmias after surgical resection is unknown.</AbstractText>The aims of this study were to quantify the VT/VF risk after surgical resect...
22,572
Underestimation of Aortic Stenosis Severity by Doppler Mean Gradient during Atrial Fibrillation: Insights from Aortic Valve Weight.
Doppler mean gradient (MG) can underestimate aortic stenosis (AS) severity when obtained during atrial fibrillation (AF) compared with sinus rhythm (SR). Aortic valve weight (AVW) is a flow-independent measure of AS severity. The objective of this study was to determine whether AVW or AVW/MG ratio was increased in AF v...
22,573
Established Clinical Prediction Rules for Bleeding Had Mediocre Discrimination in Left Ventricular Assist Device Recipients.
Left ventricular assist devices (LVAD) reduce mortality in patients with end-stage heart failure, but LVAD management is frequently complicated by bleeding. Bleeding prediction post-LVAD implantation is challenging as prediction rules for hemorrhage have not been rigorously studied in this population. We aimed to valid...
22,574
Catheter ablation of atrial fibrillation in heart failure with impaired systolic function: An updated meta-analysis of randomized controlled trials.
The recent Atrial Fibrillation Management in Congestive Heart Failure With Ablation trial did not reveal any benefit of catheter ablation in patients with atrial fibrillation (AF), advanced heart failure (HF), and severely reduced left ventricular ejection fraction (LVEF). We hypothesized that radiofrequency catheter a...
22,575
Left main and two vessels calcified coronary aneurysms presented as out of hospital cardiac arrest in young patient.
A 37-year-old patient was admitted secondary to ventricular fibrillation induced out of hospital cardiac arrest. Coronary angiogram revealed left main, left anterior descending, and right coronary arteries aneurysms. The patient underwent bypass surgery with four grafts. Ejection fraction improved from 30% upon admissi...
22,576
Long-term outcomes following catheter ablation versus medical therapy in patients with persistent atrial fibrillation and heart failure with reduced ejection fraction.
The ARC-HF and CAMTAF trials randomized patients with persistent atrial fibrillation (AF) and heart failure (HF) to early routine catheter ablation (ER-CA) versus pharmacological rate control (RC). After trial completion, delayed selective catheter ablation (DS-CA) was performed where clinically indicated in the RC gro...
22,577
The effect of stress hyperglycem&#x131;a seen &#x131;n acute ST-segment elevat&#x131;on &#x131;n myocard&#x131;al &#x131;nfarct&#x131;on on &#x131;n-hosp&#x131;tal mortal&#x131;ty.
The brief rise in blood glucose level during acute physiological stress in patients with no previous symptoms of diabetes mellitus is called stress hyperglycemia.</AbstractText>This study is conducted with 1033 patients over the age of 18 who are diagnosed with STEMI and who did not meet the exclusion criteria for 1&#x...
22,578
Atrial activation sequence changes during ventricular overdrive pacing: What is the mechanism?
We describe atrial activation sequence changes during ventricular overdrive pacing in a patient with a concealed left-sided accessory pathway and discuss its potential mechanism.
22,579
Clinical profile and 90 day outcomes of 10 851 heart failure patients across India: National Heart Failure Registry.
Limited data on the uptake of guideline-directed medical therapies (GDMTs) and the mortality of acute decompensated HF (ADHF) patients are available from India. The National Heart Failure Registry (NHFR) aimed to assess clinical presentation, practice patterns, and the mortality of ADHF patients in India.</AbstractText...
22,580
Termination of Sustained Ventricular Fibrillation During Radiofrequency Catheter Ablation.
After a ST-segment elevation inferior myocardial infarction, a patient developed multiple drug-refractory ventricular fibrillation (VF), triggered by a stereotypic premature ventricular complex. During an episode of sustained VF, catheter ablation of the moderator band terminated VF, with transition into monomorphic ve...
22,581
Esophago-Pericardial Fistula as a Rare&#xa0;and Life-Threatening Complication of Epicardial Ventricular Tachycardia&#xa0;Ablation.
We describe a rare complication of esophago-pericardial fistula after epicardial ventricular tachycardia ablation. Echocardiogram revealed evidence of pneumopericardium and additional imaging studies confirmed esophageal leak with evidence of fistula formation requiring prompt surgical repair. (<b>Level of Difficulty: ...
22,582
Effect of WenXin KeLi on Improvement of Arrhythmia after Myocardial Infarction by Intervening PI3K-AKT-mTOR Autophagy Pathway.
Myocardial infarction (MI) is an acute and serious cardiovascular disease. Arrhythmia after MI can lead to sudden cardiac death, which seriously affects the survival outcome of patients. WenXin KeLi is a Chinese patent medicine for the treatment of arrhythmia in a clinic, which can significantly improve symptoms of pal...
22,583
Case report of a patient with congenital long QT syndrome Type 2 presenting with electrical storm: do not judge a book by its cover!
Patients with congenital long QT syndrome (LQTS) are at high risk for sudden cardiac death (SCD). Although several triggers can provoke ventricular fibrillation (VF) in patients suffering from LQTS acquired heart disease in addition to LQTS should not be overlooked.</AbstractText>We present a case of a 47-year-old fema...
22,584
Impact of right atrial enlargement on clinical outcome in patients with atrial fibrillation.
Left atrial (LA) remodeling is associated with adverse cardiovascular events, including heart failure (HF) and stroke in patients with atrial fibrillation (AF). However, there are limited data on the value of right atrial (RA) remodeling in this population. We investigated the prognostic role of RA enlargement in patie...
22,585
Cardiovascular toxic effects of antitumor agents: Pathogenetic mechanisms.
Cancer treatment is associated with various side effects of antitumor agents, which increase the morbidity and mortality of these patients. Cardiovascular complications are considered to be one of the most important side effect of the anticancer drugs. The antitumor drugs that express cardiovascular effects include ant...
22,586
Keep shocking: Double sequential defibrillation for refractory ventricular fibrillation.
Double sequential defibrillation is proposed as a novel modality of managing refractory ventricular fibrillation (VF). However, existing evidence has not been enough to support this. Here, we report an interesting case of a 54-year-old male who suffered from cardiac arrest with VF rhythm. The patient did not respond to...
22,587
Impact of Left Ventricular End-Diastolic Pressure on the Outcomes of Patients Undergoing Percutaneous Coronary Intervention.
Left ventricular end-diastolic pressure (LVEDP) is an important hemodynamic marker of left ventricular performance and affects coronary perfusion. We evaluated the association of LVEDP with patient outcomes after elective or urgent percutaneous coronary intervention (PCI). We included n&#xa0;=&#xa0;49,600 patients unde...
22,588
Cardiac TRPV4 channels.
Transient Receptor Potential Vanilloid 4 (TRPV4) is expressed in numerous cell types within the heart, yet the expression levels, subcellular localization, and functional relevance of TRPV4 in cardiac myocytes is under-appreciated. Recent data indicate a critical role of TRPV4 in both atrial and ventricular myocyte bio...
22,589
Pharmacologic Therapy for Heart Failure with Preserved Ejection Fraction.
The management of heart failure with preserved ejection fraction (HFpEF) is rapidly evolving. The pharmacologic treatment of patients with HFpEF includes symptom management with diuretics and optimization of comorbidities, including hypertension, obesity, diabetes mellitus, and atrial fibrillation. Specific therapies, ...
22,590
Prognostic Impact of Landiolol in Patients with Acute Heart Failure and Atrial Fibrillation with Rapid Ventricular Rates: A Pilot Observational Study.
Guidelines recommend ventricular rate control to &lt;130 bpm during atrial fibrillation (AF) in patients with acute decompensated heart failure (ADHF) to avoid aggravating deteriorations in cardiac outputs. We aimed to evaluate the prognostic impact of landiolol in patients with ADHF and AF.</AbstractText>This observat...
22,591
The characteristics of pre-excitation syndrome concomitant with atrial tachyarrhythmia and the effect of radiofrequency ablation.
Wolff-Parkinson-White (WPW) concomitant with atrial tachyarrhythmia (ATA) has not been systemically characterized.</AbstractText>Detailed electroanatomical mapping of the right atrium (RA) and/or left atrium (LA) was performed using three-dimensional mapping and the accessory pathway (AP) was mapped.</AbstractText>WPW ...
22,592
Programmed Ventricular Stimulation as an Additional Primary Prevention Risk Stratification Tool in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Study.
A novel risk calculator based on clinical characteristics and noninvasive tests that predicts the onset of clinical sustained ventricular arrhythmias (VA) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been proposed and validated by recent studies. It remains unknown whether programmed vent...
22,593
The new 2022 ESC Guidelines on Cardio-oncology and their impact on the Acute Cardiovascular Care Society.
In this perspective piece on the recently published ESC Guidelines on Cardio-oncology and the Consensus Statements from the Acute Cardiovascular Care Association, we summarize key learning points regarding the management of acute cardiovascular disease in patients with cancer. This document outlines where other pre-exi...
22,594
Long-Term prognosis of radiofrequency catheter ablation for atrial fibrillation with different subtypes of heart failure in the era of ablation index guidance.
The long-term outcomes of ablation index (AI)-guided radiofrequency catheter ablation (RFCA) on atrial fibrillation (AF) and different subtypes of heart failure (HF) remain unknown. The aim of the study was to evaluate the long-term prognosis of AI-guided RFCA procedures in patients with AF and concomitant HF.</Abstrac...
22,595
Mitral Annular Plane Systolic Excursion (MAPSE) as a Predictor of Atrial Fibrillation Recurrence in Patients after Pulmonary Vein Isolation.
Catheter ablation (CA) with pulmonary vein isolation (PVI) has become widely used in the past years for the treatment of atrial fibrillation (AF). Mitral annular plane systolic excursion (MAPSE) is the parameter that measures left ventricular longitudinal function, and it appears to be a good early marker of LV dysfunc...
22,596
1-Year Outcomes of Cardioband Tricuspid Valve Reconstruction System Early Feasibility Study.
Tricuspid regurgitation (TR) is prevalent and undertreated, with mortality and morbidity increasing with TR severity. Given poor outcomes with medical therapy and high in-hospital mortality for isolated tricuspid valve surgery, emerging transcatheter repair devices offer a promising alternative.</AbstractText>The Edwar...
22,597
Prediction of Death or HF Hospitalization in Patients With Severe FMR: The COAPT Risk Score.
There are limited data on the predictors of death or heart failure hospitalization (HFH) in patients with heart failure (HF) with functional mitral regurgitation (FMR).</AbstractText>The aim of this study was to develop a predictive risk score using the COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percuta...
22,598
Diagnostic Accuracy of the 2016 Guideline-Based Echocardiographic Algorithm to Estimate Invasively-Measured Left Atrial Pressure by Direct Atrial Cannulation.
Although estimation of left ventricular filling pressure (LVFP) using an integrated echocardiographic algorithm is recommended, the usefulness of this algorithm has not been fully validated.</AbstractText>The purpose of this study was to investigate the reliability of an algorithmic classification system using invasive...
22,599
Autonomic nervous system and arrhythmias in structural heart disease.
The autonomic nervous system functions in a fine-tuned manner to dynamically modulate cardiac function during normal physiological state. Autonomic dysregulation in cardiac disease states such as myocardial infarction and heart failure alters this fine balance, which in turn promotes disease progression and arrhythmoge...