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2,315,600
Bio-anaerobic treatability study for PCBs-contaminated oil.
This study investigated the bio-treatability of PCB contaminated oil for the development of design and operational parameters for the bioreactor. Input of external carbon and nutrient source in the aqueous phase was found to be required for the treatment of polychlorinated biphenyls (PCBs)-contaminated oil. Addition of...
2,315,601
Low strength wastewater treatment under low temperature conditions by a novel sulfur redox action process.
The objective of this research is to make a novel wastewater treatment process activated by a sulfur-redox cycle action of microbes in low temperature conditions. This action is carried out by sulfate-reducing bacteria (SRB) and sulfur-oxidizing bacteria (SOB). The process was comprised of a UASB reactor as pre-treatme...
2,315,602
Cessation of hormone replacement therapy after reports of adverse findings from randomized controlled trials: evidence from a British Birth Cohort.
We examined the cessation of hormone replacement therapy (HRT) among British women, by educational level, social class, and cardiovascular risk factors, at the time of publicity about 2 clinical trials of HRT that were halted after adverse findings.</AbstractText>A total of 1387 women aged 57 years reported their month...
2,315,603
Ten-year absolute risk of osteoporotic fractures according to BMD T score at menopause: the Danish Osteoporosis Prevention Study.
In the non-HRT arms of the DOPS study, 10-year fracture risk was higher at each level of T score than predicted by the Kanis algorithm. Under-reporting of fractures in registers and inclusion of HRT users are probable explanations for inappropriately low fracture risk estimates for younger women.</AbstractText>Internat...
2,315,604
Effect of the Women's Health Initiative on osteoporosis therapy and expenditure in Medicaid.
Decreasing HRT use among postmenopausal women may have a reciprocal impact on other osteoporosis therapy. Time series analysis of prescribing trends for millions of Medicaid beneficiaries revealed a 57% decline in HRT without augmenting the pace of bisphosphonate use. Prescribing changes dramatically increased Medicaid...
2,315,605
The prescription of hormone replacement therapy in Spain: differences between general practitioners and gynaecologists.
The purpose of this study was to determine the frequency with which hormone replacement therapy (HRT) was prescribed and to identify physician-related factors associated with the prescription of HRT in Spain.</AbstractText>A descriptive cross-sectional survey based on a personal interview with a structured questionnair...
2,315,606
The quality of reporting of diagnostic accuracy studies in glaucoma using the Heidelberg retina tomograph.
Scanning laser tomography with the Heidelberg retina tomograph (HRT; Heidelberg Engineering, Heidelberg, Germany) has been proposed as a useful diagnostic test for glaucoma. This study was conducted to evaluate the quality of reporting of published studies using the HRT for diagnosing glaucoma.</AbstractText>A validate...
2,315,607
Knowledge-based fuzzy system for diagnosis and control of an integrated biological wastewater treatment process.
A supervisory expert system based on fuzzy logic rules was developed for diagnosis and control of a laboratory- scale plant comprising anaerobic digestion and anoxic/aerobic modules for combined high rate biological N and C removal. The design and implementation of a computational environment in LabVIEW for data acquis...
2,315,608
Development of an innovative vertical submerged membrane bioreactor (VSMBR) for simultaneous removal of organic matter and nutrients.
A novel vertical submerged membrane bioreactor (VSMBR) composed of anoxic and oxic zones in one reactor was developed in an attempt to reduce the problems concerning effective removal of pollutants from synthetic wastewater including glucose as a sole carbon source as well as membrane fouling. The optimal volume ratio ...
2,315,609
Distance of walking in childhood and femoral bone density in perimenopausal women.
Kuopio osteoporosis risk factor and prevention (OSTPRE) study is a population-based study from Eastern Finland. At baseline in 1989-91, bone densitometry of lumbar spine and femoral neck as assessed by DXA was carried out on women aged 48-58 (n = 3,222). In 1993, menarcheal age and health habits during adolescence were...
2,315,610
Reinke's oedema, hormones and hormone replacement therapy.
To study the implications of hormone replacement therapy (HRT) treatment in the pathogenesis of Reinke's oedema (via a possible pseudo-hypothyroidism effect), and also to study why the disease affects a predominantly post-menopausal female population.</AbstractText>Prospective case series study.</AbstractText>Two teach...
2,315,611
Detecting glaucoma with RADAAR: the Bridlington Eye Assessment Project.
To develop a diagnostic algorithm using rim/disc area asymmetry ratio (RADAAR) to discriminate between normal and glaucomatous eyes using the Heidelberg retina tomograph (HRT).</AbstractText>RADAAR was calculated by dividing rim/disc area ratio of the larger disc by that of the smaller disc. RADAAR normal tolerances in...
2,315,612
Vitamin D and its binding protein Gc: long-term variability in peri- and postmenopausal women with and without hormone replacement therapy.
Measurement of plasma 25-hydroxyvitamin D (25OHD) level is often used to evaluate a patient's vitamin D status. The purpose of this study was to investigate the variability in individual plasma 25OHD- and vitamin D-binding protein- (Gc) levels over a 5-year period in postmenopausal women with and without hormone replac...
2,315,613
Effects of alendronate combined with hormone replacement therapy on osteoporotic postmenopausal Chinese women.
To evaluate the effect of alendronate combined with hormone replacement therapy (HRT) on postmenopausal osteoporotic Chinese women living in Taiwan, we treated 151 women (age range, 47-70 years; mean, 61 years) with conjugated equine estrogen (0.625 mg), medroxyprogesterone 5 mg, and elemental calcium 500 mg daily with...
2,315,614
Nutrient recovery from domestic wastewater using a UASB-duckweed ponds system.
The pilot-scale wastewater treatment system used in this study comprised a 40-l UASB reactor (6-h HRT) followed by three duckweed ponds in series (total HRT 15 days). During the warm season, the treatment system achieved removal values of 93%, 96% and 91% for COD, BOD and TSS, respectively. Residual values of ammonia, ...
2,315,615
An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients.
To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients.</AbstractText>One hundred and forty-nine family members of 46 PACG patients underwent ocular examination included slit lamp biomicroscopy, gonioscopy, fundus examinati...
2,315,616
Guidelines for hormone replacement therapy of Asian women during the menopausal transition and thereafter.
These Guidelines summarize the position of an Expert Panel on Menopause in Asian Women regarding the use of hormone replacement therapy (HRT) during the menopausal transition and thereafter. They are intended to aid gynecologists, family physicians and other health-care professionals in providing optimal care to menopa...
2,315,617
The influence of premenopausal hormones on severity of climacteric symptoms and use of HRT.
There is wide variation in the severity of climacteric symptoms and we hypothesized that this could be a reflection of premenopausal hormone levels.</AbstractText>As part of a long-term cohort study of endocrine risk factors for breast cancer, blood had been collected between 1986 and 1990 from 1882 premenopausal women...
2,315,618
The long-term impact of 2-3 years of hormone replacement therapy on cardiovascular mortality and atherosclerosis in healthy women.
The effect of hormone replacement therapy (HRT) on cardiovascular risk is intensely debated. The aim of this study was to investigate the long-term effects of HRT given for a few years on all-cause and cardiovascular mortality and the severity of atherosclerosis.</AbstractText>This analysis was based on a cohort of 1,4...
2,315,619
Biodegradation kinetics of high strength oily pet food wastewater in a membrane-coupled bioreactor (MBR).
Aerobic respirometric experiments were conducted at a temperature of 40 degrees C to determine biokinetic parameters describing growth and decay of aerobic biomass acclimatized in a membrane-coupled bioreactor (MBR). The kinetic parameters were determined with the volatile fatty acids (VFA) acetic acid and propionic ac...
2,315,620
A comparison of HRT II and GDx imaging for glaucoma detection in a primary care eye clinic setting.
To evaluate the performance of the HRT II (Heidelberg retinal tomograph) and GDx (glaucoma detection) retinal nerve fibre analyzer in GDx when used in the primary care eye clinic setting for glaucoma screening.</AbstractText>The study was prospective, cross-sectional, and hospital-based. One-hundred and twelve patients...
2,315,621
Role of ovarian hormones in the regulation of protein metabolism in women: effects of menopausal status and hormone replacement therapy.
The age-related decline in fat-free mass is accelerated in women after menopause, implying that ovarian hormone deficiency may have catabolic effects on lean tissue. Because fat-free tissue mass is largely determined by its protein content, alterations in ovarian hormones would likely exert regulatory control through e...
2,315,622
No effect of vitamin K1 intake on bone mineral density and fracture risk in perimenopausal women.
Vitamin K functions as a co-factor in the post-translational carboxylation of several bone proteins, including osteocalcin.</AbstractText>The aim of this study was to investigate the relationship between vitamin K(1) intake and bone mineral density (BMD) and fracture risk in a perimenopausal Danish population.</Abstrac...
2,315,623
Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa.
Notch signaling is central to cell differentiation, organ development, and apoptosis. Upon ligand binding, the Notch intracellular domain (NotchIC) translocates to the nucleus to interact with its DNA-binding partner, RBP-Jkappa. The NotchIC-RBP-Jkappa complex activates target genes, such as those encoding the Hrt and ...
2,315,624
Does immediate hormone replacement therapy affect the oncologic outcome in endometrial cancer survivors?
The purpose of this study was to evaluate the effect of immediate hormone replacement therapy (HRT) on oncologic outcome of patients with endometrial cancer. The patients were recruited prospectively after extensive discussion of risks and benefits of HRT. Continuous daily regimen of 0.625 mg conjugated equine estrogen...
2,315,625
Translesion synthesis past equine estrogen-derived 2'-deoxyadenosine DNA adducts by human DNA polymerases eta and kappa.
Hormone replacement therapy (HRT) increases the risk of developing breast, ovarian, and endometrial cancers. Equilin and equilenin are the major components of the widely prescribed drug used for HRT. 4-Hydroxyequilenin (4-OHEN), a major metabolite of equilin and equilenin, promotes 4-OHEN-modified dC, dA, and dG DNA ad...
2,315,626
[The skin and menopause].
The estrogen deficit occurring at menopause manifests itself under various modalities in the diverse organs and their functions. Skin does not escape this global involutive process. In addition to the effects of chronological ageing, sunlight exposure and other environmental and endogenous stimuli, the climacteric appe...
2,315,627
Elutriated acid fermentation of municipal primary sludge.
The performance of a novel fermentation process, adopting a sludge blanket type configuration, for higher hydrolysis/acidogenesis of the municipal primary sludge was investigated under batch and semi-continuous conditions with varying pH and temperature. This acid elutriation slurry reactor provided higher system perfo...
2,315,628
Profile of menopausal women in west Anatolian rural region sample.
The aim of this study was to evaluate age at menopause, climacteric symptoms and related factors in women living in west Anatolian rural region of Turkey.</AbstractText>This study included 761 menopausal women living in three rural towns. Questionnaires regarding to 10 climacteric symptoms, menopausal status, sociodemo...
2,315,629
Experimental study on denitrification using coated electrode of immobilized denitrifying bacteria.
To develop a coated electrode of immobilized denitrificants and to evaluate the performance of a bioelectrochemical reactor to enhance and control denitrification.</AbstractText>Denitrifying bacteria were developed by batch incubation and immobilized with polyvinyl alcohol (PVA) on the surface of activated carbon fiber...
2,315,630
Sustained Bmp signaling is essential for cloaca development in zebrafish.
Bone morphogenetic protein (Bmp) signaling has long been known to be important for the early development of the ventral mesoderm, including blood, vasculature and kidney cells. Although Bmp genes are continually expressed in the ventral cells throughout gastrulation and somitogenesis, previous studies in zebrafish have...
2,315,631
Use of postmenopausal hormone replacement therapy and risk of non-Hodgkin's lymphoma: a Danish population-based cohort study.
Use of postmenopausal hormone replacement therapy (HRT) has been hypothesised to be associated with a reduced risk of non-Hodgkin's lymphoma (NHL), but the epidemiologic evidence is conflicting. To examine the risk of NHL in HRT users aged 40 and older, we conducted a cohort study in the County of North Jutland, Denmar...
2,315,632
Dynamics of progestogenic activity in serum following administration of Ligusticum chuanxiong.
Many women are using botanical alternatives for menopausal hormone replacement therapy (HRT) because current progestins, compounds with progesterone activity, have adverse risk profiles. However the development of phyto-progestins for HRT is hampered by the absence of basic pharmacokinetic/pharmacodynamic (PK/PD) data ...
2,315,633
Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy.
The American Women's Health Initiative study published in July 2002 caused considerable concern among hormone replacement therapy (HRT) users and prescribers in many countries. This study is an exploratory research comparing the genome-wide expression profile in whole-blood samples according to HRT use. Within the Norw...
2,315,634
Prevalence and causes of persistent use of hormone replacement therapy among postmenopausal women: a follow-up study.
In a previous study analyzing data from September 2002 to February 2003, we showed that, despite the Women's Health Initiative trial results, many women still remained on hormone replacement therapy (HRT) in an internal medicine practice. However, it is not known whether such use has persisted over time. We performed a...
2,315,635
[The interrelationship between the sectorial disc and the visual field changes in patients with normal tension glaucoma].
To investigate the changes of the sectorial discs and visual fields, and their interrelationships in patients with normal tension glaucoma (NTG).</AbstractText>26 patients with NTG were undergone the optic nerve and visual field examinations with HRT-II and HFA II in a time interval of less than 5 months. The parameter...
2,315,636
Monophasic and biphasic relaxation during motor unit tetanic contractions of variable fusion degree.
The phenomenon of transition of the monophasic relaxation into biphasic course in the unfused tetanic contractions was studied on functionally isolated motor units of the rat medial gastrocnemius muscle. The sample consisted of 16 FF, 16 FR and 10 S MUs which were stimulated with the same, digitally controlled patterns...
2,315,637
Growth and long-term hormonal therapy.
Sex hormone replacement therapy (HRT) in the female adolescent has the following goals: 1. to mimic physiologic puberty; 2. to enhance normal growth; 3. to induce and maintain normal menstruation, 4. to support normal bone maturation and calcification; 5. to initiate and maintain normal brain cell growth and brain plas...
2,315,638
[Healthy optic discs with large cups--a diagnostic challenge in glaucoma].
Healthy optic discs with large cups are often characterised to be glaucomatous in automated, morphometric analysis. The aim of this study was to investigate the variables of laser scanning tomography (LST) and nerve fibre polarimetry of these disks in comparison to small and normal sized disks.</AbstractText>117 eyes (...
2,315,639
Hormone replacement therapy in endometrial cancer survivors: new perspectives after the heart and estrogen progestin replacement study and the women's health initiative.
Dramatic shifts in prescription practices during the last 30 years have left physicians confused and uncertain about the use of hormone replacement therapy (HRT) in endometrial cancer survivors.</AbstractText>This article reviews the published literature concerning both the safety of prescribing HRT to endometrial canc...
2,315,640
Test-retest variability in structural and functional parameters of glaucoma damage in the glaucoma imaging longitudinal study.
To determine the test-retest variability in perimetric, optic disc, and macular thickness parameters in a cohort of treated patients with established glaucoma.</AbstractText>In this cohort study, the authors analyzed the imaging studies and visual field tests at the baseline and 6-month visits of 162 eyes of 162 partic...
2,315,641
Comparison of objective diagnostic tests in glaucoma: Heidelberg retinal tomography and multifocal visual evoked potentials.
To compare sensitivity and specificity of functional and structural changes in glaucoma using two objective tests: the multifocal visual evoked potential (m-VEP) and Heidelberg retinal tomography II (HRT).</AbstractText>41 glaucoma patients and 25 normal individuals participated in the study. One eye per individual was...
2,315,642
Municipal-wastewater treatment using upflow-anaerobic filters.
Three 12.5-L upflow-anaerobic filters (AF), with ceramic-saddle, plastic-ring, and crushed-stone packing, were used to evaluate the sustained treatment of municipal wastewater. The reactors were initially fed dogfood-fortified wastewater and then raw municipal wastewater, and operated at 25.4 degrees C (32 months) and ...
2,315,643
Outcome of LASIK for myopia in women on hormone replacement therapy.
To investigate the effect of hormone treatment on refractive and visual outcome after LASIK in women.</AbstractText>A retrospective review of the hospital notes of all women on hormone replacement therapy (HRT) and oral contraceptives at the time of LASIK was performed. Their refractive and visual outcomes were compare...
2,315,644
Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy.
Menopause is often associated with vaginal atrophy and related symptoms, such as vaginal dryness, burning, itching, and dyspareunia, decrease in libido and in general a decrease in the quality of life. The common treatment up to the 1990's has been the oral hormone replacement therapy (HRT), but this treatment has been...
2,315,645
Biological hydrogen production in a UASB reactor with granules. II: Reactor performance in 3-year operation.
The experiment was conducted to evaluate the performance of an upflow anaerobic sludge blanket (UASB) with granules for H(2) production from a sucrose-rich synthetic wastewater at various substrate concentrations (5.33-28.07 g-COD/L) and hydraulic retention times (HRTs) (3-30 h) for over 3 years. The kinetics of H(2) p...
2,315,646
The impact of artificial light scatter on scanning laser tomography.
The impact of cataract (which frequently occurs alongside glaucoma) on scanning laser tomography (SLT) is poorly understood. The aim of this pilot study was to determine the impact of artificial light scatter on SLT estimates of optic nerve head (ONH) topography.</AbstractText>The sample comprised 10 healthy, young sub...
2,315,647
Effects of long-term treatment with resveratrol and subcutaneous and oral estradiol administration on pituitary function in rats.
Hormone replacement therapy (HRT) has been used for several decades to treat menopausal discomforts. However, in the light of recent studies that draw attention to the potential hazards of conventional HRT, various attempts have been undertaken to search for alternatives to classical HRT. Phytoestrogens are claimed to ...
2,315,648
Are there second thoughts about the results of the WHI study?
The publication of the Women's Health Initiative (WHI) study had significant impact on the attitude of physicians and patients towards the use of hormones in the menopause. It has been estimated that 40-83% of patients using hormones ceased treatment on their own initiative following publication of the WHI results. Whi...
2,315,649
Effect of hormone replacement therapy on plasma lipoproteins and apolipoproteins, endothelial function and myocardial perfusion in postmenopausal women with estrogen receptor-alpha IVS1-397 C/C genotype and established coronary artery disease.
Effect of hormone replacement (HRT) therapy on plasma lipoproteins and apolipoproteins, endothelial function and myocardial perfusion in postmenopausal women with estrogen receptor-alpha (ER-alpha) IVS1-397 C/C genotype and established coronary artery disease.</AbstractText><AbstractText Label="BACKGROUND/AIMS" NlmCate...
2,315,650
Eosinophilic esophagitis.
Esophagitis is an increasingly diagnosed disease. Patients with gastroesophagic reflux, dysphagia, vomiting or abdominal pain, with a torpid response to the treatment, could be suffering from it.</AbstractText>A 37 year-old male patient with background of gastroesophagic reflux and dysphagia for solids since 2002, self...
2,315,651
Integration of sulphate reduction, autotrophic denitrification and nitrification to achieve low-cost excess sludge minimisation for Hong Kong sewage.
An integrated anaerobic-aerobic treatment system of sulphate-laden wastewater was proposed here to achieve low sludge production, low energy consumption and effective sulphide control. Before integrating the whole system, the feasibility of autotrophic denitrification utilising dissolved sulphide produced during anaero...
2,315,652
Combining UASB and the "fourth generation" down-flow hanging sponge reactor for municipal wastewater treatment.
A "fourth generation" down-flow hanging sponge (DHS) Reactor has been developed and proposed as an improved variant of post-treatment system for UASB treating domestic wastewater. This paper evaluates the potential of the proposed combination of UASB and DHS as a sewage treatment system, especially for developing count...
2,315,653
Development of biological filter as tertiary treatment for effective nitrogen removal: Biological filter for tertiary treatment.
A biological filtration process applicable to tertiary treatment of sewage for effective nitrogen removal was developed. It consisted of a nitrification filter (Filter 1) and/or a polishing filter with anoxic and oxic parts (Filter 2). A pilot plant set at a municipal sewage treatment plant was operated for 525 d with ...
2,315,654
Small optic cup sizes among women using tamoxifen: assessment with scanning laser ophthalmoscopy.
There is a substantial literature showing that the selective estrogen receptor modulator tamoxifen can block swelling-activated chloride channels, such as those in astrocytes. This study aimed to test the hypothesis that anatomic characteristics consistent with swelling may be measured within the optic nerve head (ONH)...
2,315,655
[Characteristics of aerobic granular sludge membrane bioreactor for wastewater treatment].
Characteristics of aerobic granular sludge membrane bioreactor (MBR) and the membrane fouling were studied with synthetic wastewater. Experimental results showed that COD removal rate could be reached over 96% under the conditions of HRT = 6h, DO 4 - 6 mg x L(-1) and the volumetric load of COD = 7.24 kg x (m3 x d)(-1)....
2,315,656
Current status of combined hormone replacement therapy in clinical practice.
Approximately 20 million women worldwide use hormone replacement therapy (HRT). Formerly, it was thought to confer beneficial cardiac protection and reduce osteoporosis in addition to relieving the symptoms of menopause. However, many recent trials have contradicted these beliefs. The risk of breast cancer associated w...
2,315,657
Decrease in herbicide concentrations and affected factors in lagoons located around Lake Biwa.
The contamination levels and changes in the concentrations in four lagoons around Lake Biwa of paddy-use herbicide were studied. Four lagoons, Sone-numa (52 days of HRT (hydraulic residence time) estimated from the lagoon volume and the average discharge at the outlet, 21 ha area), Yanagihira-ko (40 days, 5.0 ha), Noda...
2,315,658
Comparison of fundamental voice frequency between menopausal women and women at menacme.
To analyze comparatively the speaking fundamental frequency (F0) between women at menacme and women in the climacterium taking or not hormonal replacement therapy.</AbstractText>A controlled transverse study was conducted on 45 women divided into three groups of 15 women each: Group A (women aged 20-40 years with regul...
2,315,659
[Sector-based analysis of the distribution of the neuroretinal rim by confocal scanning laser in the diagnosis of glaucoma].
To evaluate the diagnostic ability of the Moorfields regression analysis (MRA; neuroretinal rim sector-based analysis) by means of confocal scanning laser.</AbstractText>200 eyes were included in this study: 101 normal subjects and 99 glaucoma patients (standard automated perimetry with glaucomatous defects -MD or CPSD...
2,315,660
Effects of long-term treatment with resveratrol and subcutaneous and oral estradiol administration on the pituitary-thyroid-axis.
The lack of estrogen during menopause is associated with various symptoms including osteoporosis, cardiovascular diseases, and menopausal symptoms. For many years, conventional hormone replacement therapy has been successfully used to treat these conditions. However, in light of recent studies that draw attention to po...
2,315,661
Effect of soluble microbial products on microbial metabolisms related to nutrient removal.
In this study, the effect of soluble microbial products (SMP) on the metabolisms related to phosphate or nitrogen removal of activated sludge was investigated. Two anaerobic-aerobic activated sludge processes were operated, one with a hydraulic retention time (HRT) of 48 h (RunL) and the other 6.4 h (RunS). The longer ...
2,315,662
Biohydrogen production in continuous-flow reactor using mixed microbial culture.
The goal of the proposed project was to develop an anaerobic fermentation process that converts negative-value organic wastes into hydrogen-rich gas in a continuous-flow reactor under different operating conditions, such as hydraulic retention time (HRT), heat treatment, pH, and substrates. A series of batch tests were...
2,315,663
[From the Cochrane Library: postmenopausal hormone replacement therapy (HRT) does not protect women against cardiovascular disease but does lead to an increased risk of venous thromboembolism].
Observational studies in the early nineteen-nineties have strongly suggested that hormone replacement therapy (HRT) has benefits for reducing cardiovascular events in postmenopausal women. A recent Cochrane systematic review assessed the effects of HRT in primary and secondary prevention of cardiovascular disease in po...
2,315,664
Anaerobic digestion of tannery soak liquor with an aerobic post-treatment.
The leather industry occupies a place of prominence in the Indian economy due to its massive potential for employment, growth and exports. The potential environmental impact of tanning is significant. This study focuses on tannery soak liquor, generated by the soaking of hides and skins, which is characterised by high ...
2,315,665
[Correlations among GDx-variable corneal compension, optical coherence tomography, and Heidelberg retina tomograph and relationships between these structural parameters and visual field indices].
In glaucoma patients, to compare the correlations among parameters measured by Heidelberg Retina Tomography(HRT) and retinal nerve fiber layer thickness (RNFLT) measured by GDx-variable corneal compensation (GDx-VCC) and optical coherence tomography (OCT), and to assess the relationship among these structural parameter...
2,315,666
Trimegestone differentially modulates the expression of matrix metalloproteinases in the endometrial stromal cell.
Matrix metalloproteinases (MMP) are considered to be of critical importance in the initiation of menstruation where MMP protein levels are reciprocally modulated by the actions of the gonadal steroid hormones, estradiol (E(2)) and progesterone (P4), with P4 being considered the principal suppressor of endometrial MMP e...
2,315,667
HRT, osteoporosis and regulatory authorities Quis custodiet ipsos custodes?
HRT has been widely used for the relief of menopausal symptoms and the prevention and treatment of post-menopausal osteoporosis. However, following the publication of the Women's Health Initiative (WHI) and the Million Women Study (MWS), regulatory authorities issued an urgent safety restriction on HRT use in preventin...
2,315,668
Process hydraulics, distributed bacterial states, and biological phosphorus removal from wastewater.
Hydraulic characteristics of biological wastewater treatment systems were shown to affect bacterial state distributions and system performance through mathematical simulations. The term "state" is used here to mean the microbial storage product and biomass content of a bacterium. The traditional approach to simulating ...
2,315,669
Comparison of disc damage likelihood scale, cup to disc ratio, and Heidelberg retina tomograph in the diagnosis of glaucoma.
To evaluate the relative diagnostic strength of cup to disc (C/D) ratio, clinical disc damage likelihood scale (DDLS), a new clinical method of documenting glaucomatous optic disc changes, and Heidelberg retina tomograph (HRT-II) in patients with glaucoma, glaucoma suspects, and normal controls.</AbstractText>Consecuti...
2,315,670
Pharmaceutical prospects of phytoestrogens.
Interest in the physiologic and pharmacologic role of bioactive compounds present in plants has increased dramatically over the last decade. Of particular interest in relation to human health are the classes of compounds known as the phytoestrogens, which embody several groups of non-steroidal estrogens, including isof...
2,315,671
Determinants of adherence to osteoporosis treatment in clinical practice.
Poor adherence to prescribed treatments is widespread in clinical practice and this can lead to potentially life-threatening events. This problem is apparently very common for osteoporosis treatment but the causes of discontinuation and low compliance are complex and poorly defined.</AbstractText>Global adherence to os...
2,315,672
The inhibition of tumor cell adhesion on human mesothelial cells (HOMC) by phospholipids in vitro.
Intraperitoneal tumor cell adhesion to extracellular matrix and to mesothelial cells mediated by integrins is an important step in developing peritoneal carcinosis. In former animal studies, we could demonstrate that intraperitoneal treatment with a new phospholipid (PL) emulsion significantly reduces the amount of per...
2,315,673
Treatment of petroleum refinery sourwater by advanced oxidation processes.
The performance of several oxidation processes to remove organic pollutants from sourwater was investigated. Sourwater is a specific stream of petroleum refineries, which contains slowly biodegradable compounds and toxic substances that impair the industrial biological wastewater treatment system. Preliminary experimen...
2,315,674
Packed cage rotating biological contactor system for treatment of cyanide wastewater.
The aim of this work was to study the efficiency of the packed cage rotating biological contactor (RBC) system with synthetic wastewater (SWW) containing 800 mg/l BOD(5) with various cyanide residue concentrations and hydraulic loading time. The results showed that cyanide had a negative effect to both the system's eff...
2,315,675
The basal and TRH stimulated levels of prolactin in low risk climacteric patients with increased breast density: a matched pair case control trial.
To detect any significant alteration of basal and TRH stimulated circulating prolactin levels in those with an extremely dense breast composition as compared to ones with a fatty pattern in mammography in climacteric patients with a low risk probability for developing invasive breast cancer within five years according ...
2,315,676
Cost-effectiveness of osteoporosis screening and treatment with hormone replacement therapy, raloxifene, or alendronate.
Recent information about osteoporosis treatments and their nonfracture side effects suggests the need for a new cost-effectiveness analysis. The authors estimate the cost effectiveness of screening women for osteoporosis at age 65 and treating those who screen positive with hormone replacement therapy (HRT), raloxifene...
2,315,677
Cancer-treatment-induced bone loss, part 2.
The pathophysiology, frequency, sequelae, diagnosis, and treatment of cancer-treatment-induced bone loss (CTIBL) are discussed.</AbstractText>CTIBL is a long-term complication associated with cancer therapies that can directly or indirectly affect bone metabolism. Although CTIBL can occur in any patient receiving a can...
2,315,678
Menopause, mild psychological stress and salivary cortisol: influence of long-term hormone replacement therapy (HRT).
Aim of the present study was to examine the adrenocortical activity in basal condition and following a mild stress exposure in long-term HRT-treated menopausal women. Menopausal women, long term users of HRT (14 subjects) were compared both to menopausal women who had never used HRT (14 subjects) and young pre-menopaus...
2,315,679
Treatment of menopausal symptoms in family medicine settings following the Women's Health Initiative findings.
This study explores trends in treatment of menopausal symptoms and use of hormone replacement therapy (HRT) in family medicine settings subsequent to the release of the Women's Health Initiative (WHI) findings.</AbstractText>Anonymous self-administered questionnaires were distributed to family medicine residents and fa...
2,315,680
Isoflavones made simple - genistein's agonist activity for the beta-type estrogen receptor mediates their health benefits.
Soy isoflavones, the focus of much research and controversy, are often referred to as "weak estrogens". In fact, genistein is a relatively potent agonist for the recently characterized beta isoform of the estrogen receptor (ERbeta). The low nanomolar serum concentrations of unconjugated free genistein achieved with hig...
2,315,681
Effect of pentachlorophenol and chemical oxygen demand mass concentrations in influent on operational behaviors of upflow anaerobic sludge blanket (UASB) reactor.
Upflow anaerobic sludge blanket (UASB) reactor that was seeded with anaerobic sludge acclimated to chlorophenols was used to investigate the feasibility of anaerobic biotreatment of synthetic wastewater containing pentachlorophenol (PCP) with additional sucrose as carbon source. Two sets of UASB reactors were operated ...
2,315,682
Influence of hormone replacement therapy on the accuracy of screening mammography.
The use of hormone replacement therapy (HRT) is currently a subject of debate because of the possibility of an increase in the incidence of breast cancer and difficulties associated with breast cancer detection. The objective of this study was to determine the influence of HRT on specificity and sensitivity in a breast...
2,315,683
A biological process that reduces metals in municipal sludge to yield sulphur enhanced biosolids.
Heavy metal contamination can often restrict or prohibit land application of municipal sludge. In the present investigation a continuous biological process with powdered elemental sulphur as energy source was examined for solubilization of metals from anaerobically digested municipal sludge. The results showed that the...
2,315,684
Effects of short-term hormone replacement on atherogenic indices in Indian postmenopausal women.
Indian ethnicity by itself is a strong risk factor for development of CAD in Indian postmenopausal women due to lower HDL levels as compared to Whites and women of oriental origin. We evaluated and compared the short-term effects of menopause, estrogen replacement therapy and combined estrogen and progestin replacement...
2,315,685
Association of serum proinsulin with hormone replacement therapy in nondiabetic older women: the Rancho Bernardo Study.
One putative benefit of hormone replacement therapy (HRT) is a reduced risk of diabetes or reduced fasting glucose level. We report here the association of HRT with proinsulin, insulin, and fasting and postchallenge glucose levels in older adults.</AbstractText>Current HRT use was validated and cross-sectionally compar...
2,315,686
Influence of disease severity and optic disc size on the diagnostic performance of imaging instruments in glaucoma.
To evaluate the influence of disease severity and optic disc size on the diagnostic accuracy of three imaging technologies for structural assessment in glaucoma: confocal scanning laser ophthalmoscopy, scanning laser polarimetry, and optical coherence tomography.</AbstractText>One hundred five patients with glaucoma an...
2,315,687
Use, intentions, and beliefs about hormone replacement therapy in women with and without diabetes.
(1) Describe women's (a) hormone replacement therapy (HRT) use patterns, (b) intentions to use or continue to use HRT among women in the early and late stages of menopause, and (c) beliefs about using HRT and (2) compare these beliefs, patterns, and intentions between women with and without diabetes 10-12 months after ...
2,315,688
Continuation of hormone replacement therapy during acute myocardial infarction after the women's health initiative study. Is it the time for change?
Hormone replacement therapy (HRT) was given for many years in order to relieve menopausal symptoms and was used for as long as symptom control was necessary. The Heart and Estrogen/Progestin Replacement Study (HERS) and Women's Health Initiative (WHI) studies showed that HRT should not be given for primary or secondary...
2,315,689
Effects of raloxifene and continuous combined hormone therapy on haemostasis variables: a multicenter, randomized, double-blind study.
Hormone replacement therapy is known to increase the risk of thromboembolic events. We compared the effects of HRT and raloxifene on some haemostasis variables.</AbstractText>In a multicenter, double-blind study, 54 healthy postmenopausal women were randomized to receive either continuous treatment with 2 mg 17beta-est...
2,315,690
[Estrogen treatment in climacteric and postmenopause after 2002. Can it still be prescribed?].
Preliminary results of the American study called Women's Health Initiative starting in July 2002, showed an increase in some health risks, such as coronary disease, stroke, invasive breast cancer and dementia in 2003, in postmenopausal users of replacement hormonal therapy (HRT) with conjugated equine estrogens (CEE) a...
2,315,691
Effect of spontaneous exercise on antioxidant capacity in rat muscles determined by electron spin resonance.
The effect of physical activity on antioxidant capacity in muscle remains unknown. This study investigated the effect of spontaneous exercise on antioxidant capacity in rat muscles determined by electron spin resonance (ESR), which is a technique for the direct detection of free radicals.</AbstractText>Ten-week-old mal...
2,315,692
[The use of the Heidelberg Retinal Tomograph in glaucoma prevention].
Altogether 2436 eyes of 1218 healthy persons from the ophthalmological point of view were examined in the screening glaucoma action by means of Heidelberg Retinal Tomograph (HRT II). In 103 persons (8.5%), the result of the examination was at least in one sector of the optic nerve head graded as "suspicious" of "out of...
2,315,693
Loyalties in clinical research on drugs: the case of hormone replacement therapy.
In this study, physicians' loyalties toward patients and pharmaceutical companies in clinical drug research are explored, using Bourdieu's conceptual tools. The utilization of estrogen supplements in so-called hormone replacement therapy (HRT) for healthy menopausal and postmenopausal women is used as a case. For over ...
2,315,694
Detection of glaucomatous optic nerve head by using Heidelberg topographic maps.
To evaluate the capacity of a new topographic map analysis to detect abnormal optic discs from healthy ones in a new cohort of subjects.</AbstractText>Only one eye was chosen randomly from each subject included in the study. In total, 20 normal eyes with a normal visual field, an IOP of &lt;22 mmHg and no history of gl...
2,315,695
Cancer-treatment-induced bone loss, part 1.
The pathophysiology, frequency, sequelae, diagnosis, and treatment of cancer-treatment-induced bone loss (CTIBL) are discussed.</AbstractText>CTIBL is a long-term complication associated with cancer therapies that can directly or indirectly affect bone metabolism. Although CTIBL can occur in any patient receiving a can...
2,315,696
Production of biomass (algae-bacteria) by using a mixture of settled swine and sewage as substrate.
This paper presents the use of a mixture of settled swine and sewage as substrate for biomass production, mainly constituted by microalgae Chlorella vulgaris and aerobic bacteria, growing outdoor at different dilution rates in a continuous mode. The experiments were carried out in 16-litre volume laboratory ponds opera...
2,315,697
Regional correlation of structure and function in glaucoma, using the Disc Damage Likelihood Scale, Heidelberg Retina Tomograph, and visual fields.
To evaluate relationships between the Disc Damage Likelihood Scale (DDLS), global and sectoral structural parameters provided by the Heidelberg Retina Tomograph (HRT), and global and regional functional loss in visual field (VF) testing.</AbstractText>Consecutive observational case series.</AbstractText>One hundred ten...
2,315,698
Hormone-related headache: pathophysiology and treatment.
Epidemiological data suggest a link between migraine and the female sex hormones. Indeed, it is known that estrogen affects various brain functions, including pain perception. The prevalence of migraine is similar in boys and girls before puberty, but is 3-fold higher in postpubertal females compared with males. Migrai...
2,315,699
Immobilized cell reactors in mineralization of dicarboxylic acid solid waste.
Dicarboxylic acid solid waste containing phthalic acid, malic acid, quinone, saturated and unsaturated dicarboxylic esters etc., are discharged in huge quantities during the crackdown of benzene over the catalyst vanadium at temperatures greater than 500 degrees C in a dicarboxylic acid manufacturing industry. Concern ...