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2,316,500 | Perspective on hormone therapy 10 years after the WHI. | The Women's Health Initiative (WHI) hormone trials are among the most influential and debated research studies in women's health in recent medical history. This year (2013) marked the 10th anniversary of the publication of the WHI results and this past decade has been nothing less than revolutionary. We have witnessed ... |
2,316,501 | Milk thistle: a future potential anti-osteoporotic and fracture healing agent. | Osteoporosis is a progressive disease of the skeleton characterised by bone fragility due to a reduction in bone mass and possibly to alteration in bone architecture that lead to a propensity to fracture with minimum trauma. Most osteoporotic fractures occur at locations rich in trabecular or cancellous bone and usuall... |
2,316,502 | Long-term stability of thermophilic co-digestion submerged anaerobic membrane reactor encountering high organic loading rate, persistent propionate and detectable hydrogen in biogas. | The performance of thermophilic anaerobic co-digestion of coffee grounds and sludge using membrane reactor was investigated for 148 days, out of a total research duration of 263 days. The OLR was increased from 2.2 to 33.7 kg-COD/m(3)d and HRT was shortened from 70 to 7 days. A significant irreversible drop in pH confi... |
2,316,503 | Successful operation of continuous reactors at short retention times results in high-density, fast-rate Dehalococcoides dechlorinating cultures. | The discovery of Dehalococcoides mccartyi reducing perchloroethene and trichloroethene (TCE) to ethene was a key landmark for bioremediation applications at contaminated sites. D. mccartyi-containing cultures are typically grown in batch-fed reactors. On the other hand, continuous cultivation of these microorganisms ha... |
2,316,504 | Establishment and assessment of a novel cleaner production process of corn grain fuel ethanol. | An integrated corn ethanol-methane fermentation system was proposed to solve the problem of stillage handling, where thin stillage was treated by anaerobic digestion and then reused to make mash for the following ethanol fermentation. This system was evaluated at laboratory and pilot scale. Anaerobic digestion of thin ... |
2,316,505 | Optimisation of the two-phase dry-thermophilic anaerobic digestion process of sulphate-containing municipal solid waste: population dynamics. | Microbial population dynamics and anaerobic digestion (AD) process to eight different hydraulic retention times (HRTs) (from 25d to 3.5d) in two-phase dry-thermophilic AD from sulphate-containing solid waste were investigated. Maximum values of gas production (1.9 ± 0.2 l H2/l/d; 5.4 ± 0.3 l CH4/l/d and 82 &#... |
2,316,506 | Continuous electricity generation in stacked air cathode microbial fuel cell treating domestic wastewater. | This study examined the continuous performance of air cathode MFC stacks for domestic wastewater treatments at two different temperatures (23 ± 3 °C and 30 ± 1 °C) and organic loading rates to determine the effects of the electrode connection and hydraulic flow mode on ... |
2,316,507 | A randomised controlled trial comparing the effects of micronized progesterone to medroxyprogesterone acetate on cardiovascular health, lipid metabolism and the coagulation cascade in women with premature ovarian insufficiency: study protocol and review of the literature. | Premature ovarian insufficiency (POI) can have significant health implications for the affected patient population, but remains a largely under researched area. There is lack of evidence from randomised controlled trials to guide clinical practice, regarding the optimal hormone replacement therapy regimens, dose and ro... |
2,316,508 | Population dynamics of methanogens and methane formation associated with different loading rates of organic acids along with ammonia: redundancy analysis. | In anaerobic processes, the population dynamics of methanogens in the methanogenic stage were monitored along with hydraulic retention times (HRTs) shift. Decreasing HRTs increased the loading rates of volatile fatty acids (VFAs) and ammonia. Methanomicrobiales (MMB) began to be dominant at longer than 12.5 days H... |
2,316,509 | Thermal pretreatment and hydraulic retention time in continuous digesters fed with sewage sludge: assessment using the ADM1. | Thermal pretreatment is an interesting technique not only for increasing sludge biodegradability, leading to higher methane productivity, but also for improving degradation rates, allowing full-scale plants to reduce the size of digesters. In this study, the Anaerobic Digestion Model No. 1 (ADM1) was used as a tool to ... |
2,316,510 | [Effects of optic disc size on progression of visual field defects in normal-tension glaucoma]. | To investigate the influence of optic disc area on the progression of visual field (VF) defects in normal-tension glaucoma (NTG). We evaluated the correlation between the right-left differences of the progression of VF defects and those of the intraocular pressure and the ocular anatomical factors.</AbstractText>Thirty... |
2,316,511 | Testosterone therapy improves the heart rate turbulence without effect on NT-proBNP level in men with metabolic syndrome. | It is now known that BNP and NT-proBNP levels are decreasing with increased BMI, regardless of other metabolic syndrome (MS) constituents. Additionally, testosterone deficiency may intensify frequency of ventricular rhythm disorders in obese individuals by inhibition of the parasympathetic system. Determination of hear... |
2,316,512 | [Variability and reproducibility of 3 methods for measuring the thickness of the nerve fiber layer]. | To estimate the variability and reproducibility of confocal tomography (HRT), scanning laser polarimetry (GDx) and optical coherence tomography (OCT-Cirrus) to determine the thickness of the layer of ganglion fibers.</AbstractText>A total of 75 normal eyes were examined twice. Inter-individual variability was analyzed ... |
2,316,513 | Fe(II) oxidation during acid mine drainage neutralization in a pilot-scale Sequencing Batch Reactor. | This study investigated Fe(II) oxidation during acid mine drainage (AMD) neutralization using CaCO3 in a pilot-scale Sequencing Batch Reactor (SBR) of hydraulic retention time (HRT) of 90 min and sludge retention time (SRT) of 360 min in the presence of air. The removal kinetics of Fe(II), of initial concentration 1,03... |
2,316,514 | Continuous cultivation of photosynthetic bacteria for fatty acids production. | In the present work, we introduced a novel approach for microbial fatty acids (FA) production. Photosynthetic bacteria, Rhodobacter sphaeroides KD131, were cultivated in a continuous-flow, stirred-tank reactor (CFSTR) at various substrate (lactate) concentrations. At hydraulic retention time (HRT) 4d, cell concentratio... |
2,316,515 | Double-stranded RNA-binding protein 4 is required for resistance signaling against viral and bacterial pathogens. | Plant viruses often encode suppressors of host RNA silencing machinery, which occasionally function as avirulence factors that are recognized by host resistance (R) proteins. For example, the Arabidopsis R protein, hypersensitive response to TCV (HRT), recognizes the turnip crinkle virus (TCV) coat protein (CP). HRT-me... |
2,316,516 | Enhancing dissolved oxygen control using an on-line hybrid fuzzy-neural soft-sensing model-based control system in an anaerobic/anoxic/oxic process. | An on-line hybrid fuzzy-neural soft-sensing model-based control system was developed to optimize dissolved oxygen concentration in a bench-scale anaerobic/anoxic/oxic (A(2)/O) process. In order to improve the performance of the control system, a self-adapted fuzzy c-means clustering algorithm and adaptive network-based... |
2,316,517 | Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi. | The degradation of 30 trace organic contaminants (TrOC) by a white-rot fungus-augmented membrane bioreactor (MBR) was investigated. The results show that white-rot fungal enzyme (laccase), coupled with a redox mediator (1-hydroxy benzotriazole, HBT), could degrade TrOC that are resistant to bacterial degradation (e.g. ... |
2,316,518 | Diagnostic Performance of the ISNT Rule for Glaucoma Based on the Heidelberg Retinal Tomograph. | We determined the accuracy of the inferior > superior > nasal > temporal (ISNT) neuroretinal rim area rule and its variants in adult Asian populations, and evaluated whether disc area impacts its performance characteristics.</AbstractText>Participants in the Singapore Malay Eye Study (SiMES) and Singapore Indi... |
2,316,519 | Separation of competitive microorganisms using anaerobic membrane bioreactors as pretreatment to microbial electrochemical cells. | Anaerobic membrane bioreactors (AnMBRs) as pretreatment to microbial electrochemical cells (MECs) were first assessed for improving energy recovery. A dual-chamber MEC was operated at hydraulic retention time (HRT) ranging from 1 to 8d, while operating conditions for an AnMBR were fixed. Current density was increased f... |
2,316,520 | Operating aerobic wastewater treatment at very short sludge ages enables treatment and energy recovery through anaerobic sludge digestion. | Conventional abattoir wastewater treatment processes for carbon and nutrient removal are typically designed and operated with a long sludge retention time (SRT) of 10-20 days, with a relatively high energy demand and physical footprint. The process also generates a considerable amount of waste activated sludge that is ... |
2,316,521 | Non-steroidal anti-inflammatory drug use and cervical cancer risk: a case-control study using the Clinical Practice Research Datalink. | Non-steroidal anti-inflammatory drugs (NSAIDs) have many anticarcinogenic properties via the inhibition of cyclooxygenase 2 (COX-2). Only one study, a cohort study examining risk of all cancers, investigated their role in cervical cancer with inconsistent findings between non-aspirin NSAIDs and aspirin. The aim of this... |
2,316,522 | Corneal imaging of intrastromal femtosecond laser treatment for presbyopia (Intracor(®)). | To evaluate anatomic appearance and corneal cellular modifications after monocular Intracor(®) procedure with two different anterior segment imaging techniques within the first postoperative year.</AbstractText>Four patients underwent an Intracor(®) procedure in one eye performed at Clinique de la vision, and... |
2,316,523 | Association between polymorphisms in glutathione peroxidase and selenoprotein P genes, glutathione peroxidase activity, HRT use and breast cancer risk. | Breast cancer (BC) is one of the most common cancers in women. Evidence suggests that genetic variation in antioxidant enzymes could influence BC risk, but to date the relationship between selenoproteins and BC risk remains unclear. In this report, a study population including 975 Danish cases and 975 controls matched ... |
2,316,524 | Biosynthesis of poly(hydroxybutyrate-hydroxyvalerate) from the acclimated activated sludge and microbial characterization in this process. | This study investigated the effects of substrate composition (acetate and propionate) on synthesis of various mix of poly(hydroxybutyrate-hydroxyvalerate) (P(HB/HV)) from activated sludge, which was acclimated using a single carbon (acetate) and mixed carbons (acetate and propionate). Results of batch P(HB/HV) producti... |
2,316,525 | Simultaneous bioreduction of nitrate and chromate using sulfur-based mixotrophic denitrification process. | This study aims at evaluating simultaneous chromate and nitrate reduction using sulfur-based mixotrophic denitrification process in a column reactor packed with elemental sulfur and activated carbon. The reactor was supplemented with methanol at C/N ratio of 1.33 or 2. Almost complete denitrification was achieved at in... |
2,316,526 | Laser scanning tomography in the EPIC-Norfolk Eye Study: principal components and associations. | To describe Heidelberg Retina Tomograph (HRT) measures, their principal components, and their associations in a British population.</AbstractText>The European Prospective Investigation of Cancer (EPIC)-Norfolk Eye Study is nested within a multicenter cohort study. Measurements were taken with the HRT-2 and the software... |
2,316,527 | [Effects of HRT on fate of typical polycyclic musk by A2O process]. | Fate of galaxolide (HHCB) and tonalide (AHTN) during the A2O process was investigated under different hydraulic retention time (HRT). Solid phase extraction (SPE) and gas chromatography mass spectrometry (GC/MS) were applied to determine the concentrations of the targets in the aqueous phase and sewage sludge. The resu... |
2,316,528 | A meta-analysis of reference values of leptin concentration in healthy postmenopausal women. | There are numerous reports about the leptin concentration (LC) in postmenopausal women (PW). Changes in LC can elicit different clinical outcomes. We systematically analyzed the LC in PW.</AbstractText>A search was conducted in original English-language studies published from 1994 to October 2012 in the following datab... |
2,316,529 | Generalised modelling approach for anaerobic co-digestion of fermentable substrates. | A general methodology to implement fermentable soluble substrates in the IWA Anaerobic Digestion Model No. 1 (ADM1) that extends its application to anaerobic co-digestion of multiple substrates is presented. The approach considers the fermentation of new soluble substrates, not originally described in ADM1, as channell... |
2,316,530 | Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis. | Some studies have shown that long-term gonadotropin-releasing hormone (GnRH) agonist administration before in vitro fertilization/intracytoplasmic sperm in infertile women with endometriosis or adenomyosis significantly increases the chances of pregnancy. We were interested in whether long-term GnRH agonist pretreatmen... |
2,316,531 | Assessment of mammographic density in postmenopausal women during long term hormone replacement therapy. | To assess long-term effects of different hormone replacement therapy (HRT) regimens on mammographic density.</AbstractText>One hundred sixty-five postmenopausal women were treated with the same HRT during 5 years: 38 received transdermal estradiol, 78 cyclic combined therapy and 49 continuous combined therapy. Mammogra... |
2,316,532 | Comparison of Heidelberg retina tomography, optical coherence tomography and Humphrey visual field in early glaucoma diagnosis. | To determine the value of optic disc parameters and perimetric defects in the early diagnosis of patients with primary open-angle glaucoma (POAG).</AbstractText>Optic disc parameters and perimetry were compared among patients in the early stage of POAG, patients with suspected POAG and healthy control subjects, using H... |
2,316,533 | Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density. | Although studies have demonstrated a positive association between hormone replacement therapy (HRT) and breast cancer risk, this association may vary by patient factors.</AbstractText>We analyzed 1642824 screening mammograms with 9300 breast cancer cases in postmenopausal women aged 45 years or older derived from the B... |
2,316,534 | Hormone use and risk for lung cancer: a pooled analysis from the International Lung Cancer Consortium (ILCCO). | The association between oral contraceptive (OC) use, hormone replacement therapy (HRT) and lung cancer risk in women is still debated.</AbstractText>We performed a pooled analysis of six case-control studies (1961 cases and 2609 controls) contributing to the International Lung Cancer Consortium. Potential associations ... |
2,316,535 | Ozonation of ibuprofen: a degradation and toxicity study. | This paper presents the results obtained in the degradation of ibuprofen by ozonation. This study aims to evaluate the degradation of ibuprofen by ozonation once the operating variables have been optimized, investigating the degradation and degradation efficiency of the compound and assessing the toxic effect of ibupro... |
2,316,536 | Sludge accumulation and conversion to methane in a septic tank treating domestic wastewater or black water. | Although the septic tank is the most applied on-site system for wastewater pre-treatment, limited research has been performed to determine sludge accumulation and biogas production in the tank. Therefore a dynamic mathematical model based on the Anaerobic Digestion Model No. 1 (ADM1) was developed for anaerobic digesti... |
2,316,537 | Allopregnanolone and mood disorders. | Certain women experience negative mood symptoms during the menstrual cycle and progesterone addition in estrogen treatments. In women with PMDD increased negative mood symptoms related to allopregnanolone increase during the luteal phase of ovulatory menstrual cycles. In anovulatory cycles no symptom or sex steroid inc... |
2,316,538 | Confocal microscopy in biopsy proven argyrosis. | Purpose. To evaluate the confocal microscopy findings of a 46-year-old male with bilateral biopsy proven argyrosis. Materials and Methods. Besides routine ophthalmologic examination, anterior segment photography and confocal microscopy with cornea Rostoch module attached to HRT II (Heidelberg Engineering GmbH, Heidelbe... |
2,316,539 | "Hook and roll technique" using an articulating hook cautery to provide a critical view during single-incision laparoscopic cholecystectomy. | We describe a new simple and easy technique called the "Hook and roll technique" (HRT) that uses an articulating hook cautery to provide a critical view during single incision laparoscopic cholecystectomy (SILC). A 2-cm incision is made at the umbilicus to insert three 5-mm trocars or a multichannel port. After dissect... |
2,316,540 | Hormone replacement therapy in females can decrease the risk of lung cancer: a meta-analysis. | The purpose of the present meta-analysis was to determine the relationship between hormone replacement therapy (HRT) and lung cancer risk in females. Publications were reviewed and obtained through a PubMed, EMBASE database and Cochrane Library literature search up to May, 2012. The detailed numbers of patients in diff... |
2,316,541 | Molecular pathways: Estrogen pathway in colorectal cancer. | Worldwide, colorectal cancer has a higher incidence rate in men than in women, suggesting a protective role for sex hormones in the development of the disease. Preclinical data support a role for estrogen and its receptors in the initiation and progression of colorectal cancer and establishes that protective effects of... |
2,316,542 | Habit reversal training in trichotillomania: guide for the clinician. | Trichotillomania (hair-pulling disorder) involves repetitive hair pulling that can cause significant distress and impairment in functioning. Both children and adults suffer from the disorder. Habit reversal training (HRT) is the trichotillomania treatment with the most empirical support. HRT begins with developing an i... |
2,316,543 | Reducing the risk of foaming and decreasing viscosity by two-stage anaerobic digestion of sugar beet pressed pulp. | Anaerobic digestion (AD) of sugar beet pressed pulp (SBPP) is a promising treatment concept. It produces biogas as a renewable energy source making sugar production more energy efficient and it turns SBPP from a residue into a valuable resource. In this study one- and two-stage mono fermentation at mesophilic condition... |
2,316,544 | Morphology of optic disc through heidelberg retina tomograph in retinal vein occlusions alone or in combination with primary open angle glaucoma. | To evaluate the morphology of optic discs in eyes suffering from retinal vein occlusion (RVO) alone or in combination with primary open-angle glaucoma (POAG).</AbstractText>Prospective, observational study. 48 consecutive patients were enrolled, 30 with unilateral RVO diagnosis, 18 with unilateral retinal vein occlusio... |
2,316,545 | Biological nutrient removal with limited organic matter using a novel anaerobic-anoxic/oxic multi-phased activated sludge process. | An anaerobic-anoxic/oxic (A2/O) multi-phased biological process called "phased isolation tank step feed technology (PITSF)" was developed to force the oscillation of organic and nutrient concentrations in process reactors. PITSF can be operated safely with a limited carbon source in terms of low carbon requirements and... |
2,316,546 | Methanosarcinaceae and acetate-oxidizing pathways dominate in high-rate thermophilic anaerobic digestion of waste-activated sludge. | This study investigated the process of high-rate, high-temperature methanogenesis to enable very-high-volume loading during anaerobic digestion of waste-activated sludge. Reducing the hydraulic retention time (HRT) from 15 to 20 days in mesophilic digestion down to 3 days was achievable at a thermophilic temperature (5... |
2,316,547 | Applicability of standard parameters in diagnostics of primary open-angle glaucoma. | The aim of this study was to evaluate the sensitivity, specificity, and likelihood ratio of standard diagnostic parameters C/D, NFI, and MD and their applicability in diagnostics of primary open-angle glaucoma.</AbstractText>This study included 194 subjects (371 eyes), ages 30 to 65 years old, who underwent full ophtha... |
2,316,548 | Investigation of PPCPs in wastewater treatment plants in Greece: occurrence, removal and environmental risk assessment. | In the present work, an extensive study on the presence of eighteen pharmaceuticals and personal care products (PPCPs) in eight wastewater treatment plants (WWTPs) of Greece has been conducted. The study covered four sampling periods over 1-year, where samples (influents; effluents) from eight WWTPs of various cities i... |
2,316,549 | Treatment of azo dye-containing synthetic textile dye effluent using sulfidogenic anaerobic baffled reactor. | This study aims at investigating azo dye reduction performance of a sulfidogenic anaerobic baffled reactor (ABR) for around 400 days. ABR was operated at 30 °C in a temperature-controlled room and hydraulic retention time (HRT) was kept constant at 2 days. The robustness of ABR was assessed under varying azo dye l... |
2,316,550 | Confocal microscopy in a case of crystalline keratopathy in a patient with smouldering multiple myeloma. | We report the clinical and confocal microscopic findings of the cornea in a patient with smouldering multiple myeloma (SMM) using in vivo scanning laser confocal microscopy. A 72-year-old female underwent a complete ophthalmological examination including slit-lamp biomicroscopy with digital photography, HRT II laser sc... |
2,316,551 | Notch and Wnt signaling in the emergence of hematopoietic stem cells. | Hematopoietic stem cells (HSC), which reside in the marrow of adult mammals and sustain hematopoiesis for the lifetime of the organism, are specified and generated during embryonic development. We are just beginning to understand how HSC develop from more primitive cells and the complexity of the signaling pathways inv... |
2,316,552 | Enhancement of denitrification in a down-flow hanging sponge reactor by effluent recirculation. | A down-flow hanging sponge reactor, constructed by connecting three identical units in series, was applied to the treatment of artificial wastewater containing phenol and ammonia under high salinity conditions (10.9 g-Cl(-)/L). The theoretical hydraulic retention time (HRT) of each unit was 4 h (total HRT = 12 h). To e... |
2,316,553 | Removal of nitrogen from wastewater with perennial ryegrass/artificial aquatic mats biofilm combined system. | To develop a cost-effective combined phytoremediation and biological process, a combined perennial ryegrass/artificial aquatic mat biofilm reactor was used to treat synthetic wastewater. Influent ammonium loading, reflux ratio, hydraulic retention time (HRT) and temperature all had significant effects on the treatment ... |
2,316,554 | Optimisation of single-phase dry-thermophilic anaerobic digestion under high organic loading rates of industrial municipal solid waste: population dynamics. | Different high feed organic loading rates (OLRs) (from 5.7 g to 46.0 g TVS/l/d) or hydraulic retention times (HRTs) (from 15 d to 2 d) in single-phase dry-thermophilic anaerobic digestion (AD) of organic fraction municipal solid waste (OFMSW) were investigated. The specific gas production (SGP) values (0.25-0.53 m(3)/k... |
2,316,555 | [Study on sulfur-based autotrophic denitrification with different electron donors]. | Sulphur-based autotrophic denitrification was applied to treat the low concentration nitrate-contaminated water. Different electron donors, namely, elemental sulfur, sulfide and thiosulfate, were used in three continuous reactors to compare the denitrification performance. When treating the low concentration nitrate-co... |
2,316,556 | Population attributable risks for modifiable lifestyle factors and breast cancer in New Zealand women. | Breast cancer is the most commonly diagnosed invasive cancer in New Zealand women and modifiable lifestyle risk factors may contribute to this.</AbstractText>To estimate population attributable risks for modifiable lifestyle factors and breast cancer in New Zealand.</AbstractText>Estimates of the magnitude of the impac... |
2,316,557 | Systematic review about breast cancer incidence in relation to hormone replacement therapy use. | Several studies report a decrease in breast cancer incidence subsequent to the decrease in hormone replacement therapy (HRT) use. But its magnitude and the time-lag may vary between countries. This may reflect differences in populations, previous type and prevalence of HRT use and breast cancer screening.</AbstractText... |
2,316,558 | Randomized Trials Built on Sand: Examples from COPD, Hormone Therapy, and Cancer. | The randomized controlled trial is the fundamental study design to evaluate the effectiveness of medications and receive regulatory approval. Observational studies, on the other hand, are essential to address post-marketing drug safety issues but have also been used to uncover new indications or new benefits for alread... |
2,316,559 | Association between recent herpes zoster but not herpes simplex infection and subsequent risk of malignancy in women: a retrospective cohort study. | The association between herpes zoster and subsequent cancer risk is still unclear. Consequently, doubts remain regarding the need for investigation of herpes patients for co-existing or subsequent malignancy. This is a retrospective cohort study comparing cancer risk in patients after herpes zoster and age-/sex-matched... |
2,316,560 | [Plants supporting the fight against the symptoms of menopause]. | The tradition of the use of plants resources in the fight against many diseases dates back to antiquity. Herbal medicine is used in the fight against less severe, as well as serious diseases. In view of the serious consequences of the use of hormone replacement therapy (HRT) to combat the symptoms of menopause are incr... |
2,316,561 | Investigation of Anaerobic Fluidized Bed Reactor/ Aerobic Moving Bed Bio Reactor (AFBR/MMBR) System for Treatment of Currant Wastewater. | Anaerobic treatment methods are more suitable for the treatment of concentrated wastewater streams, offer lower operating costs, the production of usable biogas product. The aim of this study was to investigate the performance of an Anaerobic Fluidized Bed Reactor (AFBR)-Aerobic Moving Bed Bio Reactor (MBBR) in series ... |
2,316,562 | Gene therapy for cancer through adenovirus vector‑mediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting. | Loss of (genomic) imprinting (LOI) of the insulin-like growth factor 2 gene (IGF2) is a common epigenetic abnormality in many human cancers. IGF2 imprinting is regulated by differentially methylated domains (DMD) in the imprinting control region that is located between IGF2 and H19 on human chromosome 11. In the presen... |
2,316,563 | Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia. | Accumulation of advanced oxidation protein products (AOPPs) is prevalent in obesity, advanced maternal age, diabetes mellitus, and polycystic ovary syndrome. Alterations in the regulation and signaling of angiogenic pathways have been recognized as a link between these conditions and pre-eclampsia. To investigate the p... |
2,316,564 | Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice. | Mucopolysaccharidosis (MPS) are a family of related disorders caused by a mutation in one of the lysosomal exoglycosidases which leads to the accumulation of glycosaminoglycans (GAGs). MPS VII, caused by a mutation in β-glucuronidase, manifests hepatomegaly, skeletal dysplasia, short stature, corneal clouding, an... |
2,316,565 | Power of magic hands: parent-driven application of habit reversal to treat complex stereotypy in a 3-year-old. | The authors assessed the effectiveness of habit reversal training (HRT) to treat a complex motor stereotypy in a healthy 3-year-old female.</AbstractText>This data-based case study involved training parents in HRT to deliver the parent-driven intervention to the child. The frequency of the child's behaviors was estimat... |
2,316,566 | Pretreatment of 2,4-dinitroanisole (DNAN) producing wastewater using a combined zero-valent iron (ZVI) reduction and Fenton oxidation process. | A combined zero-valent iron (ZVI) reduction and Fenton oxidation process was tested for the pretreatment of 2,4-dinitroanisole (DNAN) producing wastewater. Operating conditions were optimized and overall performance of the combined process was evaluated. For ZVI process, almost complete reduction of nitroaromatic compo... |
2,316,567 | Estrogenic and chemopreventive activities of xanthones and flavones of Syngonanthus (Eriocaulaceae). | The possible benefits of some bioactive flavones and xanthones present in plants of the genus Syngonanthus prompted us to screen them for estrogenic activity. However, scientific research has shown that such substances may have undesirable properties, such as mutagenicity, carcinogenicity and toxicity, which restrict t... |
2,316,568 | How sex hormones promote skeletal muscle regeneration. | Skeletal muscle regeneration efficiency declines with age for both men and women. This decline impacts on functional capabilities in the elderly and limits their ability to engage in regular physical activity and to maintain independence. Aging is associated with a decline in sex hormone production. Therefore, elucidat... |
2,316,569 | [Morphology of the optic nerve disc in eyes with myopia in correlation to the refractive error]. | To asses morphology of the optic nerve disc in correlation to the refractive error in eyes with myopia.</AbstractText>The examined group consisted of 47 patient (84 eyes), age 20 to 36 years (mean age 28 +/- 4,5), with refractive error -4.00 Dsph to -14.25 Dsph +/- 0.75 Dcyl. This group was divided into two subgroups a... |
2,316,570 | Assessment of sewage sludge bioremediation at different hydraulic retention times using mixed fungal inoculation by liquid-state bioconversion. | Sustainable, environmental friendly, and safe disposal of sewage treatment plant (STP) sludge is a global expectation. Bioremediation performance was examined at different hydraulic retention times (HRT) in 3-10 days and organic loading rates (OLR) at 0.66-7.81 g chemical oxygen demand (COD) per liter per day, with mix... |
2,316,571 | Exogenous and endogenous hormones in relation to glioma in women: a meta-analysis of 11 case-control studies. | Previous investigations of glioma risk in women have focused on oral contraceptive (OC), hormone replacement therapy (HRT), and reproductive factors. However, the results of published studies were inconclusive and inconsistent. Thus, a meta-analysis based on published case-control studies was performed to assess the ro... |
2,316,572 | Health tourism on the rise? Evidence from the Balance of Payments Statistics. | The study assesses the presence and magnitude of global trends in health tourism using health-related travel (HRT) spending reported in the International Monetary Fund's Balance of Payments Statistics database. Linear regression and quantile regression are applied to estimate secular trends of the import and export of ... |
2,316,573 | Calibration of hydrodynamic behavior and biokinetics for TOC removal modeling in biofilm reactors under different hydraulic conditions. | In this study, total organic carbon (TOC) biodegradation was simulated by GPS-X software in biofilm reactors with carriers of plastic rings and glass beads under different hydraulic conditions. Hydrodynamic model by retention time distribution and biokinetic measurement by in-situ batch test served as two significant p... |
2,316,574 | Decentralized application of anaerobic digesters in small poultry farms: performance analysis of high rate self mixed anaerobic digester and conventional fixed dome anaerobic digester. | Biomethanation of poultry litter was studied in conventional fixed dome anaerobic digester (CFDAD) and high rate self mixed anaerobic digester (SMAD) for possible decentralized application in poultry farms generating litter in the range of 500 kg/day. The performance of CFDAD and SMAD was compared. The study revealed t... |
2,316,575 | A phase-III prevention trial of low-dose tamoxifen in postmenopausal hormone replacement therapy users: the HOT study. | Postmenopausal hormone replacement therapy (HRT) relieves menopausal symptoms and may decrease mortality in recently postmenopausal women, but increases breast cancer risk. Low-dose tamoxifen has shown retained activity in phase-II studies.</AbstractText>We conducted a phase-III trial in 1884 recently postmenopausal wo... |
2,316,576 | Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis. | There are a number of pharmacological agents for the treatment of bone mineral loss and osteoporosis. Hormone replacement therapy (HRT) with estrogen is an established treatment, but it has several adverse side effects and can increase the risk of cancer, heart disease, and stroke. There is increasing interest in nutri... |
2,316,577 | HRT optimization, using transdermal estradiol plus micronized progesterone, a safer HRT. | Hormone replacement therapy (HRT) remains the gold standard for treatment of climacteric symptoms in menopausal women; it is relatively safe in healthy subjects for at least 5 years, provided it had been initiated before the age of 60 years and/or within 10 years from menopause. Estrogen probably adds some cardioprotec... |
2,316,578 | Hormone replacement therapy and the association with coronary heart disease and overall mortality: clinical application of the timing hypothesis. | Conclusions from randomized controlled trial (RCT) data over the past 10 years has spanned from presumed harm to consistency with observational data that hormone replacement therapy (HRT) decreases the risk for coronary heart disease (CHD) as well as overall mortality in women who are recently postmenopausal. Multiple ... |
2,316,579 | Behaviour of pharmaceuticals and endocrine disrupting chemicals in simplified sewage treatment systems. | This work assessed the behaviour of nine pharmaceuticals and/or endocrine disrupting chemicals (EDCs) in demo-scale upflow anaerobic sludge blanket reactors (UASB reactors) coupled to distinct simplified post-treatment units (submerged bed, polishing ponds, and trickling filters) fed on raw sewage taken from a municipa... |
2,316,580 | Waiting for a hand: saccadic reaction time increases in proportion to hand reaction time when reaching under a visuomotor reversal. | Although eye movement onset typically precedes hand movement onset when reaching to targets presented in peripheral vision, arm motor commands appear to be issued at around the same time, and possibly in advance, of eye motor commands. A fundamental question, therefore, is whether eye movement initiation is linked or y... |
2,316,581 | Phosphorus removal in a sulfur-limestone autotrophic denitrification (SLAD) biofilter. | The sulfur-limestone autotrophic denitrification (SLAD) biofilter was able to remove phosphorous from wastewater during autotrophic denitrification. Parameters influencing autotrophic denitrification in the SLAD biofilter, such as hydraulic retention time (HRT), influent nitrate (NO3(-)), and influent PO4(3-) concentra... |
2,316,582 | Ethanol production from glucose and xylose by immobilized Thermoanaerobacter pentosaceus at 70 °C in an up-flow anaerobic sludge blanket (UASB) reactor. | The newly isolated extreme thermophilic ethanologen Thermoanaerobacter pentosaceus was immobilized in different support materials in order to improve its ethanol production ability. In batch fermentation, a maximum ethanol yield of 1.36 mol mol(-1) consumed sugars was obtained by T. pentosaceus immobilized on rapeseed ... |
2,316,583 | Effect of cultivated species and retention time on the performance of constructed wetlands. | This study aimed to evaluate the influence of hydraulic retention time (HRT) and cultivated species in vertical-flow constructed wetlands (CW) on the removal of pollutants found in swine wastewater. The applied organic loading per unit area was 20 g m(-2) d(-1) of COD in nine cylindrical CW planted with Cyperus sp., He... |
2,316,584 | Evaluation of a microwave-heating anaerobic digester treating municipal secondary sludge. | This work experimentally determined the effect of microwave irradiation on the anaerobic digestion of municipal secondary sludge in semi-continuous mesophilic digesters at hydraulic retention times (HRT) of 15, 10 and 5 days when microwaves were used as a heating source. A microwave-heating anaerobic digester (MHAD) wa... |
2,316,585 | Oral estradiol and dydrogesterone combination therapy in postmenopausal women: review of efficacy and safety. | HRT is known to be effective for the relief of menopausal symptoms and prevention of osteoporosis. HRT should be tailored to the woman, enhancing the beneficial effects of the treatment while minimizing the risks. It is difficult to evaluate data on particular preparations of HRT and the different dosages in isolation.... |
2,316,586 | Use of real-time QPCR in biokinetics and modeling of two different ammonia-oxidizing bacteria growing simultaneously. | A real-time quantitative polymerase chain reaction (QPCR) was used to evaluate biokinetic coefficients of Nitrosomonas nitrosa and N. cryotolerans clusters growing simultaneously in a batch mode of ammonia oxidation. The mathematical models based on Monod equation were employed to describe the competitive relationship ... |
2,316,587 | Simulation and optimization of ammonia removal at low temperature for a double channel oxidation ditch based on fully coupled activated sludge model (FCASM): a full-scale study. | An optimal operating condition for ammonia removal at low temperature, based on fully coupled activated sludge model (FCASM), was determined in a full-scale oxidation ditch process wastewater treatment plant (WWTP). The FCASM-based mechanisms model was calibrated and validated with the data measured on site. Several im... |
2,316,588 | Modulation of skeletal muscle performance and SERCA by exercise and adiponectin gene therapy in insulin-resistant rat. | This study addresses the potential application of adiponectin gene therapy and exercise in protection against skeletal muscle dysfunction in type 2 diabetes mellitus (T2DM) while focusing on the role of sarco and endoplasmic reticulum Ca(+2) ATPase (SERCA) and Glut4. 50 rats were divided into five groups: control, T2DM... |
2,316,589 | Submerged aerated bio-filter (SAB)--a post treatment option for UASB effluent treating sewage. | This paper presents exploratory results of the performance of submerged aerated bio-filter (SAB-1.5 L) for the post treatment of UASB effluent treating sewage in order to bring the effluent quality in compliance with discharge standards. The study was carried out in three stages with varied dissolved oxygen (DO) levels... |
2,316,590 | [Effects of oral dydrogesterone on clinical outcomes of frozen-thawed embryo transfer cycles]. | To investigate the effects of oral dydrogesterone for luteal phase support after frozen embryo transfer (FET) cycles on the clinical outcomes.</AbstractText>A total of 1643 FET cycles in our center between January, 2010 and September, 2011 were analyzed. The patients were divided into group A with natural-cycle FET and... |
2,316,591 | Hormone replacement therapy increases the risk of cranial meningioma. | We investigated the influence of hormone replacement therapy (HRT) use on the risk of meningioma in a population-based setting.</AbstractText>We conducted a nationwide case-control study in Denmark based on population-based administrative and health registries. The study included all female patients aged 55-84 years wi... |
2,316,592 | [Effect of C/N ratio on nitrite accumulation during denitrification process]. | Effect of C/N (COD/NO3(-) -N) ratio on nitrite accumulation during denitrification process was investigated in a sequencing batch reactor (SBR) with acetic sodium as the electron donor. The nitrite accumulation ratio was 45% at a C/N ratio of 3 during operation in SBR with HRT at 6 h. According to the results of batch ... |
2,316,593 | Denitrification of simulated municipal wastewater treatment plant effluent using a three-dimensional biofilm-electrode reactor: operating performance and bacterial community. | A three-dimensional biofilm-electrode reactor (3D-BER) was applied for nitrate removal from simulated municipal wastewater treatment plant (WWTP) effluent. It was found that when the influent C/N ratio ranged from 1.0 to 2.0, both heterotrophic and autotrophic denitrifying microorganisms played important roles in nitra... |
2,316,594 | Optimizing the thermophilic hydrolysis of grass silage in a two-phase anaerobic digestion system. | Thermophilic hydrolysis of grass silage (GS) at 55 °C with organic loading rates (OLRs) of 6.5, 5, 2.5 and 1.0 kg VS m(-3) days(-1) and hydraulic retention times (HRT) of 10, 6, 4 and 2 days were evaluated in 12 glass bioreactors side by side. The hydrolytic process was measured by variation in pH, volatile solids... |
2,316,595 | Distribution and determinants of C-reactive protein in the older adult population: European Prospective Investigation into Cancer-Norfolk study. | C-reactive protein (CRP) is a well-documented predictor of cardiovascular diseases and mortality. We aimed to better understand the distribution and determinants of CRP in the population.</AbstractText>Study participants were men and women aged 40-79 in the UK-based EPIC-Norfolk population-based cohort study. CRP was m... |
2,316,596 | Combined coagulation-flocculation and sequencing batch reactor with phosphorus adjustment for the treatment of high-strength landfill leachate: experimental kinetics and chemical oxygen demand fractionation. | The treatability of high-strength landfill leachate is challenging and relatively limited. This study examines the feasibility of treating high-strength landfill leachate (chemical oxygen demand [COD]: 7,760-11,770 mg/L, biochemical oxygen demand [BOD5]: 2,760-3,569 mg/L, total nitrogen [TN] = 980-1,160 mg/L) using a s... |
2,316,597 | [Specifity of optic disc evaluation in healthy subjects with large optic discs and physiologic cupping using confocal scanning laser ophthalmoscopy]. | Imaging methods of the optic nerve head appear to have an increasing impact in glaucoma diagnosis. The aim of this study is to evaluate the specifity of the Heidelberg Retina Tomograph (software version 1.7 and 3.0) in subjects with physiological cupping and large optic discs.</AbstractText>27 eyes of 27 subjects (mean... |
2,316,598 | Nitrification performance in a membrane bioreactor treating industrial wastewater. | The influence of industrial (pharmaceutical and chemical) wastewater composition on membrane bioreactor (MBR) performance was investigated in a pilot-scale installation. The study focussed on nitrification performance, which was evaluated based on influent and effluent parameters as well as batch nitrification rate tes... |
2,316,599 | Dosing free nitrous acid for sulfide control in sewers: results of field trials in Australia. | Intermittent dosing of free nitrous acid (FNA), with or without the simultaneous dosing of hydrogen peroxide, is a new strategy developed recently for the control of sulfide production in sewers. Six-month field trials have been carried out in a rising main sewer in Australia (150 mm in diameter and 1080 m in length) t... |
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