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2,319,400
Study on COD and nitrogen removal efficiency of domestic sewage by hybrid carrier biofilm reactor.
A moving bed biofilm reactor (MBBR) is a kind of commonly used biological sewage treatment process. A carrier, the core of MBBR, could directly affect the treatment efficiency of MBBR. In this experiment, a hybrid carrier composed of an MBBR carrier and fluidized bed porous carrier was innovatively utilized to treat lo...
2,319,401
Estimation of total energy requirement for sewage treatment by a microbial fuel cell with a one-meter air-cathode assuming Michaelis-Menten COD degradation.
Calculations of chemical oxygen demand (COD) degradation in sewage by a microbial fuel cell (MFC) were used to estimate the total energy required for treatment of the sewage. Mono-exponential regression (MER) and the Michaelis-Menten equation (MME) were used to describe the MFC's COD removal rate (CRR). The tubular MFC...
2,319,402
Moderately Hypofractionated Radiotherapy Without Chemotherapy in Elderly or Frail Patients With Head and Neck Cancer.
Comorbidity and frailty are relevant limitations of normofractionated combined radiochemotherapy for squamous cell head and neck cancer (HNSCC), especially in elderly patients. This retrospective study aimed to evaluate the efficacy and toxicity of moderately hypofractionated radiotherapy (HRT) without chemotherapy in ...
2,319,403
SARS-CoV-2 mutations acquired during serial passage in human cell lines are consistent with several of those found in recent natural SARS-CoV-2 variants.
Since the outbreak of coronavirus disease (COVID-19) in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into diverse variants. Here, an early isolate of SARS-CoV-2 was serially passaged in multiple cell lines of human origin in triplicate, and selected mutations were compared to those fou...
2,319,404
Rationale and design of the CORE (COrticosteroids REvised) study: protocol.
Corticosteroids are an important pillar in many anti-inflammatory and immunosuppressive treatment regimens and are available in natural and synthetic forms, which are considered equipotent if clinical bioequivalence data are used. Current clinical bioequivalence data are however based on animal studies or studies with ...
2,319,405
Towards practical integration of MBR with electrochemical AOP: Improved biodegradability of real pharmaceutical wastewater and fouling mitigation.
In the current study, we report enhanced treatment of real pharmaceutical wastewater by integration of Electrooxidation (EO) with Membrane Bio-Reactor (MBR) for the first time. Integrated pre-pilot EO-MBR plant consisted of a 3D printed electrochemical flowcell equipped with graphite electrodes installed in the effluen...
2,319,406
Role of Estrogens in Menstrual Migraine.
Migraine is a major neurological disorder affecting one in nine adults worldwide with a significant impact on health care and socioeconomic systems. Migraine is more prevalent in women than in men, with 17% of all women meeting the diagnostic criteria for migraine. In women, the frequency of migraine attacks shows vari...
2,319,407
Continuous antibiotic attenuation in algal membrane photobioreactor: Performance and kinetics.
The attenuation of 10 mixed antibiotics along with nutrients in a continuous flow mode by four freshwater microalgae (Haematococcus pluvialis, Selenastrum capricornutum, Scenedesmus quadricauda, and Chlorella vulgaris) was examined in membrane photobioreactors (MPBRs). At lab-scale, consistent removal of both antibioti...
2,319,408
Consensus-led recommendations supporting choice and personalisation of Hormone replacement therapy in menopause care.
Inequity of access and choice to different hormone replacement therapy (HRT) products across the UK has been suggested (Hillman, 2020). While, the cause is not entirely understood, potential contributors include conflicting national guidance, economic deprivation and a local formulary approach. With a diverse and growi...
2,319,409
A laboratory-scale study of residential greywater treatment with sugarcane in a constructed wetland.
Due to India's population expansion, water recycling is critical to reducing water scarcity. The purpose of this study is to discuss the recycling and reuse of domestic greywater. The horizontal subsurface flow constructed wetland (HSSF-CW) was employed to treat greywater, with bioenergy crops replacing decorative plan...
2,319,410
Metagenomic analysis of microbial community and metabolic pathway of simultaneous sulfide and nitrite removal process exposed to divergent hydraulic retention times.
The role of hydraulic retention time (HRT) on S<sup>0</sup> production was assessed through metagenomics analyses. Considering comprehensive performance for the tested HRTs (0.25-13.33&#xa0;h), the optimal HRT was 1&#xa0;h, while respective sulfide and nitrite loading rate could reach 6.84&#xa0;kg S/(m<sup>3</sup>&#xb7...
2,319,411
Hydrodynamic cavitation pre-treatment of urban waste: Integration with acidogenic fermentation, PHAs synthesis and anaerobic digestion processes.
Urban waste can be valorized within a biorefinery approach, producing platform chemicals, biopolymers and energy. In this framework, hydrodynamic cavitation (HC) is a promising pre-treatment for improving biodegradability due to its high effectiveness and low cost. This paper deals with the effect of HC pre-treatment o...
2,319,412
Development and application of a predictive model for advanced wastewater treatment by adsorption onto powdered activated carbon.
This work presents a mathematical method to describe adsorptive removal of organic micropollutants (OMPs) and dissolved organic carbon (DOC) from wastewater treatment plant effluent using powdered activated carbon (PAC). The developed model is based on the tracer model (TRM) as a modification of the ideal adsorbed solu...
2,319,413
[Pituitary immune-related adverse events induced by programmed cell death protein 1 inhibitors in advanced lung cancer patients: A report of 3 cases].
Pituitary immune-related adverse events induced by programmed cell death protein 1 inhibitors in advanced lung cancer patients: A report of 3 cases SUMMARY Programmed cell death protein 1 (PD-1) and its ligand 1 (PD-L1) have been widely used in lung cancer treatment, but their immune-related adverse events (irAEs) requ...
2,319,414
Trust in the Danger Zone: Individual Differences in Confidence in Robot Threat Assessments.
Effective human-robot teaming (HRT) increasingly requires humans to work with intelligent, autonomous machines. However, novel features of intelligent autonomous systems such as social agency and incomprehensibility may influence the human's trust in the machine. The human operator's mental model for machine functionin...
2,319,415
A divided flow aerobic-anoxic baffled reactor for simultaneous nitrification-denitrification of domestic wastewater.
A novel aerobic-anoxic baffled reactor is designed for the effective denitrification of real domestic wastewater without an external carbon source. The flow is divided between two inlets at the beginning of each zone to provide a carbon source for the denitrifying bacteria. The effects of operating parameters such as t...
2,319,416
Treatment of printing ink wastewater using a continuous flow electrocoagulation reactor.
Printing ink wastewater from printing facilities is difficult to treat because of its heavy pollutant load (chemical oxygen demand - COD, color and total suspended solids - TSS). In this study undiluted printing ink wastewater with high COD (i.e., 20,000&#xa0;mgL<sup>-1</sup>) was treated using a highly efficient, cont...
2,319,417
Anaerobic digestion of urea pretreated water hyacinth removed from Lake Abaya; bio-methane potential, system stability, and substance conversion.
Water hyacinth (<i>Eichhornia crassipes</i>) is characterized as an aquatic plant that can grow very rapidly and freely float over water, and covers the top surface of water. It prevents the penetration of sunlight and reduces nutrients and oxygen from water bodies, and can adversely affect the aquatic ecosystem; howev...
2,319,418
Moving-bed biofilm reactor combined with three-dimensional electrochemical pretreatment (MBBR-3DE) for 2,4-D herbicide treatment: application for real wastewater, improvement of biodegradability.
2,4-Dichlorophenoxyacetic acid (2,4-D) is a herbicide that is considered as a carcinogenic and highly toxic contaminant, and due to its biological and chemical stability, its degradation is very difficult. Therefore, this study aimed to investigate a hybrid system's efficiency of three-dimensional electrochemical (3DE)...
2,319,419
Efficient removal of phosphorus from constructed wetlands using solidified lanthanum/aluminum amended attapulgite/biochar composite as a novel phosphorus filter.
Developing a suitable substrate with high phosphorus (P) sorption capacity, low solubility, and high hydraulic loading for constructed wetlands (CWs) is crucial for their functions. In this study, we used attapulgite and biochar as base materials to prepare a lanthanum/aluminum (La/Al) amended attapulgite/biochar compo...
2,319,420
Performance optimization and microbial community evaluation for domestic wastewater treatment in a constructed wetland-microbial fuel cell.
Constructed wetland-microbial fuel cell system (CW-MFC), an attractive technology still under study, has shown to improve domestic wastewater treatment efficiency and generate bioelectricity. This work investigated the effect of multiple factors on the performance optimization for the pollutants removal and bioelectric...
2,319,421
Phytotherapic approach in menopause: light and darkness.
Menopause is a critical period of the woman life, characterized by a peculiar modification in estrogens concentration and accompanied by different signs and symptoms. To prevent and contrast unfavorable consequences of menopause, different therapeutic approaches could be evaluated. The hormone replacement therapy (HRT)...
2,319,422
Identifying targets for increased biogas production through chemical and organic matter characterization of digestate from full-scale biogas plants: what remains and why?
This study examines the destiny of macromolecules in different full-scale biogas processes. From previous studies it is clear that the residual organic matter in outgoing digestates can have significant biogas potential, but the factors dictating the size and composition of this residual fraction and how they correlate...
2,319,423
Effect of sulfamethoxazole on nitrate removal by simultaneous heterotrophic aerobic denitrification.
The increase in mariculture activities worldwide has not only led to a rise of nitrogen compounds in the ecosystem but has also intensified the accumulation of antibiotics in both terrestrial and marine environments. This study focused on the effect of typical antibiotics, specifically sulfamethoxazole (SMX) on nitrate...
2,319,424
Fertilization, embryo culture, and clinical results using low lactate embryo culture medium for pre-culture, insemination, and beyond.
We focused on the metabolism of oocytes in pre-culture and insemination and compared these results between our existing fertilization medium, GEMS Fertilisation Medium (GEMS group) (Merck BioPharma) and Continuous Single Culture Medium-NX Complete (CSCM-NXC group) (FUJIFILM Irvine Scientific).</AbstractText>Patients un...
2,319,425
Anoxic/oxic treatment without biomass recycle.
The Anoxic/Oxic (A/O) process involves recirculating mixed liquor between its A and O tanks so that nitrate produced in the O tank can be used to for denitrification with influent COD in the A tank. Because biomass is recirculated along with nitrate, A/O operation leads to similar microbial communities in the A and O t...
2,319,426
Fate and removal of emerging contaminants in anaerobic fluidized membrane bioreactor filled with thermoplastic gel as biofilm support.
The Anaerobic Fluidized Membrane Bioreactor (AnFMBR) is a membrane-based hybrid technology that can overcome the limitations of conventional anaerobic sewage treatment. Although previous studies have demonstrated excellent performance in the removal of conventional organic pollutants, further research into the removal ...
2,319,427
Skin, hair and beyond: the impact of menopause.
The skin is an endocrine organ and a major target of hormones such as estrogens, androgens and cortisol. Besides vasomotor symptoms (VMS), skin and hair symptoms often receive less attention than other menopausal symptoms despite having a significant negative effect on quality of life. Skin and mucosal menopausal sympt...
2,319,428
Comparison of Perinatal Outcomes of Letrozole-Induced Ovulation and Hormone Replacement Therapy Protocols in Patients With Abnormal Ovulation Undergoing Frozen-Thawed Embryo Transfer: A Propensity Score Matching Analysis.
With the increasing use of frozen embryo transfer (FET), the best endometrial preparation protocol is continuously being discussed. The hormone replacement therapy (HRT) cycle and letrozole-induced ovulation (L-OI) cycle are available protocols for patients with abnormal ovulation. Previous comparisons of the two proto...
2,319,429
Biohydrogen and biomethane production from food waste using a two-stage dynamic membrane bioreactor (DMBR) system.
This study examined a two-stage dynamic membrane bioreactor (DMBR) system for biohydrogen and biomethane production from food waste (FW) in mesophilic condition. The two-stage DMBR system enabled high-rate H<sub>2</sub> and CH<sub>4</sub> production from particulate feedstock by enhanced microorganism retention. Chemic...
2,319,430
Systematic review update and meta-analysis of randomized and non-randomized controlled trials of ovarian stimulation versus artificial cycle for endometrial preparation prior to frozen embryo transfer in women with polycystic ovary syndrome.
This systematic review and meta-analysis aimed to compare the short-term reproductive and long-term obstetric outcomes after endometrial preparations by ovarian stimulation protocols and hormone replacement therapy (HRT) in women with polycystic ovary syndrome (PCOS) prior to frozen embryo transfer (FET).</AbstractText...
2,319,431
Pilot trial of a technology assisted treatment for trichotillomania.
The present study examined the usability, acceptability, feasibility, and preliminary efficacy of a prototype wrist-worn motion detection device and accompanying mobile app, developed by HabitAware<sup>&#xae;</sup>, as a system for delivering self-administered Habit Reversal Training (HRT). As an exploratory aim, the e...
2,319,432
Solids retention time dependent, tunable diatom hierarchical micro/nanostructures and their effect on nutrient removal.
The hierarchical three-dimensional (3D) micro/nanostructures of diatoms make them a promising biomaterial for fabricating nanomaterials, producing bioactive pharmaceuticals or nutraceuticals, and removing micropollutants. For diatom production in a continuous flow system, little is known how bioreactor operating parame...
2,319,433
Bioaugmentation for low C/N ratio wastewater treatment by combining endogenous partial denitrification (EPD) and denitrifying phosphorous removal (DPR) in the continuous A<sup>2</sup>/O - MBBR system.
Endogenous partial denitrification (EPD) and denitrifying phosphorous removal (DPR) were combined in a novel A<sup>2</sup>/O - MBBR (Anaerobic Anoxic Oxic - Moving Bed Biofilm Reactor) system for low carbon/nitrogen (C/N) ratio wastewater treatment. The DPR performance was compared and the nutrient metabolism was eluci...
2,319,434
Performance intensification of constructed wetland technology: a sustainable solution for treatment of high-strength industrial wastewater.
The objectives of this study were to: (1) assess the intensification of chemical oxygen demand (COD) and phosphate (PO<sub>4</sub>-P) removal; and (2) generate a set of rate constants of COD degradation (k<sub>COD</sub>) and phosphate (k<sub>PO4-P</sub>) removal for the treatment of industrial wastewater (WW) using int...
2,319,435
The relationship between serum oestrogen levels and clinical outcomes of hormone replacement therapy-frozen embryo transfer: a retrospective clinical study.
This study aimed to explore the relationship between serum oestrogen (E2</sub>) levels before endometrial transformation and pregnancy outcomes of hormone replacement therapy-frozen embryo transfer (HRT-FET) cycles, which has been investigated for years without any consensus.</AbstractText>A retrospective cohort study ...
2,319,436
Optimize the Preparation of Novel Pyrite Tailings Based Non-sintered Ceramsite by Plackett-Burman Design Combined With Response Surface Method for Phosphorus Removal.
The large amount of untreated pyrite tailings has caused serious environmental problems, and the recycling of pyrite tailings is considered as an attractive strategy. Here, we reported a novel non-sintered ceramsite prepared with pyrite tailings (PTNC) as the main active raw material for phosphorus control, and the dos...
2,319,437
Post-treatment neuroendocrine outcomes among pediatric brain tumor patients: Is there a difference between proton and photon therapy?
Pediatric brain tumor patients are vulnerable to radiotherapy (RT) sequelae including endocrinopathies. We compared post-RT neuroendocrine outcomes between pediatric brain tumor patients receiving photons (XRT) versus protons (PRT).</AbstractText>Using a prospectively maintained single-institution database, we analyzed...
2,319,438
A longitudinal perspective of hormone replacement therapies (HRTs) on neuromotor capabilities in males with 47,XXY (Klinefelter syndrome).
The purpose of this study was to delineate the effects of variable hormone replacement therapies on neuromotor function in a large cohort of males with 47,XXY from birth to adulthood.</AbstractText>A total of 270 participants aged 16 days to 17 years 11 months prenatally diagnosed with 47,XXY were assessed by their ped...
2,319,439
Outdoor demonstration-scale flat plate photobioreactor for resource recovery with purple phototrophic bacteria.
To make purple phototrophic bacteria (PPB)-based technologies a reality for resource recovery, research must be demonstrated outdoors, using scaled reactors. In this study, a 10&#xa0;m long PPB-enriched flat plate photobioreactor (FPPBR) with a volume of 0.95&#xa0;m<sup>3</sup> was operated for 253 days, fed with poult...
2,319,440
Endometriosis does not seem to be an influencing factor of hypertensive disorders of pregnancy in IVF / ICSI cycles.
To evaluate whether the incidence of hypertensive disorders of pregnancy (HDP) in pregnant women was related to endometriosis (EM), ovulation and embryo vitrification technology.</AbstractText>A retrospective cohort study was conducted on the clinical data of 3674 women who were treated with IVF / ICSI in the Reproduct...
2,319,441
Bio-capture of Cr(VI) in a denitrification system: Electron competition, long-term performance, and microbial community evolution.
Chromium is widely applied in industries as an important metal resource, but the discharge of Cr(VI) containing wastewater leads to the loss of chromium resources. This study proposed a bio-capture process of chromium in a denitrification system. The bio-capture potentiality was explored by investigating the electron c...
2,319,442
Machine learning-assisted identification of bioindicators predicts medium-chain carboxylate production performance of an anaerobic mixed culture.
The ability to quantitatively predict ecophysiological functions of microbial communities provides an important step to engineer microbiota for desired functions related to specific biochemical conversions. Here, we present the quantitative prediction of medium-chain carboxylate production in two continuous anaerobic b...
2,319,443
The Role of Hi-Tech Devices in Assessment of Corneal Healing in Patients with Neurotrophic Keratopathy.
To prove the role of high-tech investigation in monitoring corneal morphological changes in patients with neurotrophic keratopathy (NK) using Keratograph 5M (K5M) and anterior segment OCT (AS-OCT), corneal healing was monitored with Keratograph 5M (Oculus, Wetzlar, Germany) and AS-OCT (DRI, Triton, Topcon, Tokyo, Japan...
2,319,444
Response Surface Optimization of Biophotocatalytic Degradation of Industrial Wastewater for Bioenergy Recovery.
The continuous combustion of fossil fuels and industrial wastewater pollution undermines global environmental and socio-economic sustainability. Addressing this necessitates a techno-scientific revolution to recover the renewable energy potential of wastewater towards a circular economy. Herein, a developed biophotocat...
2,319,445
Response Surface Methodology for Optimization of Rotating Biological Contactor Combined with External Membrane Filtration for Wastewater Treatment.
A large amount of wastewater is directly discharged into water bodies without treatment, causing surface water contamination. A rotating biological contactor (RBC) is an attached biological wastewater treatment process that offers a low energy footprint. However, its unstable removal efficiency makes it less popular. T...
2,319,446
Down-Regulation Ovulation-Induction Leads to Favorable Outcomes in a Single Frozen-Thawed Blastocyst Transfer RCT.
Elective single embryo transfer (eSET) has been increasingly advocated to achieve the goal of delivering a single healthy baby. A novel endometrial preparation approach down-regulation ovulation-induction (DROI) proposed by our team was demonstrated in an RCT that DROI could significantly improve the reproductive outco...
2,319,447
In vivo symmetric multi-contrast MRI brain templates and atlas for spontaneously hypertensive rats.
Spontaneously hypertensive rats (SHRs) are a valuable animal model of essential hypertension. The increasing use of SHRs in neuroimaging has generated an urgent demand for a template set that provides a reference for advanced data analysis. Structural T2-weighted magnetic resonance imaging (MRI), diffusion tensor imagi...
2,319,448
Cluster analysis demonstrates co-existing sites of fragility fracture and associated comorbidities.
We undertook cluster analysis in 11,003 patients who had sustained&#x2009;&#x2265;&#x2009;1 fragility fracture, to find associations between fracture sites and comorbidities. We identified three distinct groups of fracture sites and four clusters of fractures and comorbidities. Knowledge of factors associated with frac...
2,319,449
Mapping bacterial diversity and metabolic functionality of the human respiratory tract microbiome.
The Human Respiratory Tract (HRT) is colonized by various microbial taxa, known as HRT microbiota, in a manner that is indicative of mutualistic interaction between such microorganisms and their host.</AbstractText>To investigate the microbial composition of the HRT and its possible correlation with the different compa...
2,319,450
Ovarian recovery via autologous platelet-rich plasma: New benchmarks for condensed cytokine applications to reverse reproductive aging.
Health and life expectancy gains have pushed the overall number of menopausal patients to record levels. Because maternal age at first pregnancy also continues to rise, it is unsurprising that reduced birth rates are consistently reported across many populations. Both trends severely strain national demographics and pr...
2,319,451
Nitrogen transformation in slightly polluted surface water by a novel biofilm reactor: Long-term performance and microbial population characteristics.
This study proposes a modular floating biofilm reactor (MFBR) for in situ nitrogen removal from slightly polluted water in rivers using enriched indigenous microorganisms. Its main structure is a 60 cm &#xd7; 60 cm &#xd7; 90 cm rectangular reactor filled with hackettens. After a 96-day startup, the removal efficiencies...
2,319,452
Nitrogen removal performance of anammox immobilized fillers in response to seasonal temperature variations and different operating modes: Substrate utilization and microbial community analysis.
Four anaerobic ammonium oxidation (anammox) immobilized filler reactors (R1: 33 &#xb0;C-normal, R2: seasonal temperature-normal, R3: seasonal temperature-feast, R4: seasonal temperature-starvation) were established to study the response of anammox immobilized fillers to seasonal temperature changes and different operat...
2,319,453
Integrated emergent-floating planted reactor for textile effluent: Removal potential, optimization of operational conditions and potential forthcoming waste management strategy.
Native emergent and floating plants; local reed grass (Phragmites karka) and water hyacinth (Eichhornia crassipes), respectively, were used to treat textile wastewater using an integrated emergent-floating planted reactor (IEFPR) system at hydraulic retention times (HRTs) of 8, 14, and 19 days. Real textile effluent ha...
2,319,454
BMI and Contraceptives Affect New Age-, Sex-, and Puberty-adjusted IGF-I and IGFBP-3 Reference Ranges Across Life Span.
Various clinical factors influencing serum levels of insulin-like growth factor I (IGF-I) and its binding protein 3 (IGFBP-3) are not entirely consistently described.</AbstractText>We asked whether body mass index (BMI), contraceptive drugs (CDs), and hormone replacement therapy (HRT) have potential effects on data for...
2,319,455
Study protocol: navigating access to gender care in Ireland-a mixed-method study on the experiences of transgender and non-binary youth.
There has been a global increase in demand for gender-specific healthcare services and a recognition that healthcare access is complex and convoluted, even in countries with well-developed healthcare services. Despite evidence in Ireland supporting the improvement in physical and mental health following access to gende...
2,319,456
A semi-industrial scale AnMBR for municipal wastewater treatment at ambient temperature: performance of the biological process.
A semi-industrial scale AnMBR plant was operated for more than 600 days to evaluate the long-term operation of this technology at ambient temperature (ranging from 10 to 27 <sup>&#x25cb;</sup>C), variable hydraulic retention times (HRT) (from 25 to 41 h) and influent loads (mostly between 15 and 45 kg COD&#xb7;d<sup>-1...
2,319,457
The novel incorporation of aromatase inhibitor in hormonal replacement therapy cycles: a randomized controlled trial.
Does the incorporation of the aromatase inhibitor, letrozole, in hormone replacement therapy (HRT) improve the pregnancy outcome in vitrified-warmed blastocyst transfer cycles?</AbstractText>A randomized controlled trial; HRT was used in all cycles. Exogenous oestradiol, 6 mg daily started on day 2 or day 3 of the cycl...
2,319,458
Optimizing the radiomics-machine-learning model based on non-contrast enhanced CT for the simplified risk categorization of thymic epithelial tumors: A large cohort retrospective study.<Pagination><StartPage>150</StartPage><EndPage>160</EndPage><MedlinePgn>150-160</MedlinePgn></Pagination><ELocationID EIdType="doi" Val...
Microbial fuel cells (MFCs) have attracted widespread interest due to their capability to generate power while treating wastewater. In the present investigation, rice mill wastewater (RMW) was treated in a dual-chamber MFC with a biological cathode (MFC<sub>B</sub>), in which anaerobic treatment was provided in the ano...
2,319,459
Clinical outcomes of personalized frozen-thawed embryo transfer timing for patients with recurrent implantation failure.
Recurrent implantation failure (RIF) is a critical problem for assisted reproduction technology. High-quality embryos and the synchronization endometrium both have great significance. How to get the optimal endometrial receptivity is a challenge for implantation and pregnancy of infertile patients with RIF. The objecti...
2,319,460
The association between different hormone replacement therapy use and the incidence of lung cancer: a systematic review and meta-analysis.
Many peri- and postmenopausal women use hormone replacement therapy (HRT) to relieve menopausal symptoms. However, the side effects of different HRT use (ever/current/former vs.</i> never HRT use) on lung cancer risk in women were not completely consistent. Thus, we conducted this meta-analysis to examine the connectio...
2,319,461
Impact of endometrial preparation on early pregnancy loss and live birth rate after frozen embryo transfer: a large multicenter cohort study (14 421 frozen cycles).
Does the endometrial preparation protocol (artificial cycle (AC) vs natural cycle (NC) vs stimulated cycle (SC)) impact the risk of early pregnancy loss and live birth rate after frozen/thawed embryo transfer (FET)?</AbstractText>In FET, ACs were significantly associated with a higher pregnancy loss rate and a lower li...
2,319,462
Advanced nitrogen removal in a single return anaerobic/aerobic/anoxic/aerobic (A<sub>n</sub>OAO) bioreactor treating municipal wastewater through hydroxylamine addition: Performance and microbial community.
The NH<sub>2</sub>OH dosing strategy for nitrogen removal was investigated in a single return continuous-flow anaerobic/aerobic/anoxic/aerobic (A<sub>n</sub>OAO) reactor fed with real municipal wastewater. A high nitrite accumulation ratio of 98% was achieved in only two days by continuously adding 10&#xa0;mg/L NH<sub>...
2,319,463
Influence of the hydraulic retention time on the removal of emerging contaminants in an anoxic-aerobic algal-bacterial photobioreactor coupled with anaerobic digestion.
This work evaluated, for the first time, the performance of an integral microalgae-based domestic wastewater treatment system composed of an anoxic reactor and an aerobic photobioreactor, coupled with an anaerobic digester for converting the produced algal-bacterial biomass into biogas, with regards to the removal of 1...
2,319,464
Reconstitution of prenyltransferase activity on nanodiscs by components of the rubber synthesis machinery of the Para rubber tree and guayule.
Natural rubber of the Para rubber tree (Hevea brasiliensis) is synthesized as a result of prenyltransferase activity. The proteins HRT1, HRT2, and HRBP have been identified as candidate components of the rubber biosynthetic machinery. To clarify the contribution of these proteins to prenyltransferase activity, we estab...
2,319,465
Risk of breast cancer with HRT depends on therapy type and duration.
The studyVinogradova Y, Coupland C, Hippisley-Cox J. Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases. <i>BMJ</i> 2020;371:m3873. To read the full NIHR Alert, go to: https://evidence.nihr.ac.uk/alert/risk-of-breast-cancer-with-hrt-depends-t...
2,319,466
Effect of Hearing Rehabilitation Therapy Program in Hearing Aid Users: A Prospective Randomized Controlled Study.
Despite sufficient hearing gains, many patients with hearing loss have difficulty using hearing aids due to poor word recognition ability. This study was performed to introduce our hearing rehabilitation therapy (HRT) program for hearing aid users and to evaluate its effect on hearing improvement.</AbstractText>In this...
2,319,467
Pilot scale microbial fuel cells using air cathodes for producing electricity while treating wastewater.
Microbial fuel cells (MFCs) can generate electrical energy from the oxidation of the organic matter, but they must be demonstrated at large scales, treat real wastewaters, and show the required performance needed at a site to provide a path forward for this technology. Previous pilot-scale studies of MFC technology hav...
2,319,468
Ag-TiO<sub>2</sub>/biofilm/nitrate interface enhanced visible light-assisted biodegradation of tetracycline: The key role of nitrate as the electron accepter.
Due to the pivotal role of Ag-TiO<sub>2</sub>/biofilm/nitrate interface, enhanced visible light-assisted biodegradation of tetracycline (TC) in anoxic system was realized through both batch experiment and long-term operation in this study. The results of the batch experiment elucidated that 50&#xa0;mg L<sup>-1</sup> TC...
2,319,469
Care reality of menopausal women in Germany: healthcare research using quantitative (SHI claims data) and qualitative (survey) data collection.
The transition from the fertile phase of life to menopause is associated with numerous physical changes. Hormone replacement therapy (HRT), as the most effective and efficient form of drug treatment, involves the use of oestrogens and progestins with the aim of increasing health-related quality of life through symptom ...
2,319,470
Contrast-enhanced CT-based radiomics model for differentiating risk subgroups of thymic epithelial tumors.
To validate a contrast-enhanced CT (CECT)-based radiomics model (RM) for differentiating various risk subgroups of thymic epithelial tumors (TETs).</AbstractText>A retrospective study was performed on 164 patients with TETs who underwent CECT scans before treatment. A total of 130 patients (approximately 79%, from 2012...
2,319,471
Identification of factors affecting removal of antibiotic resistance genes in full-scale anaerobic digesters treating organic solid wastes.
Efficiencies of removing antibiotic resistance genes (ARGs) and intI1 were explored using eight full-scale anaerobic digesters. The digesters demonstrated different characteristics on the basis of substrate types (food waste, manure or sludge); configuration (single or two-stage); temperature (psychrophilic, mesophilic...
2,319,472
Development of an MFC-biosensor for determination of Pb<sup>+2</sup>: an assessment from computational fluid dynamics and life cycle assessment perspectives.
Microbial fuel cell (MFC)-based biosensor sensing has emerged as an innovative approach to in situ and immediate monitoring of substrate concentration. MFC-biosensor uses bioanode as a sensing element. In this study, the performance of MFC-biosensor, operated with Pb<sup>+2</sup>, was studied at different hydraulic ret...
2,319,473
A proof-of-concept experimental study for vacuum-driven anaerobic biosolids fermentation using the IntensiCarb technology.
This study demonstrates the potential of an innovative anaerobic treatment technology for municipal biosolids (IntensiCarb), which relies on vacuum evaporation to decouple solids and hydraulic retention times (SRT and HRT). We present proof-of-concept experiments using primary sludge and thickened waste activated sludg...
2,319,474
Preliminary cost variance modeling to compare autologous intraovarian platelet-rich plasma vs. standard hormone replacement therapy for menopause management.
Menopause symptoms and hormone replacement therapy (HRT) are among the most common reasons patients seek gynecological advice. Although at least half of all women in developed countries will use HRT during their lifetime, the treatment is not without risk and guidance on HRT is mixed. Greater awareness of HRT risks fro...
2,319,475
Effect of mixing intensity on biodegradation of phenol in a moving bed biofilm reactor: Process optimization and external mass transfer study.
In this work, an effort has been made to design the process variables and to analyse the impact of mixing intensity on mass transfer diffusion in a moving bed biofilm reactor (MBBR). A lab-scale MBBR, filled with Bacillus cereus GS2 IIT (BHU) immobilized-polyethylene biocarriers, was employed to optimize the process va...
2,319,476
[Effect of iodine-bromine baths on stress-systems indicators in children with autism spectrum disorders].
The continuous increase in the prevalence of autism spectrum disorders (ASD) in the population, the debatable nature of many aspects of etiology, pathogenesis, and treatment of these disorders justify the urgent need for the development of effective medical rehabilitation methods affecting the pathogenetic mechanisms.E...
2,319,477
Treatment of aquatic medium containing common and emerging contaminants using an aero-electrochemical process based on graphite cathode and three metal oxides alloy as anode: Central composite design and photo/sono-enhancement.
An aero-electrochemical advanced oxidation process (aero-EAOP) equipped with graphite cathode and dimensionally stable anodes was utilized for the treatment of aquatic media containing common and emerging contaminants. Among various anode materials, the application of Ti/RuO<sub>2</sub>/IrO<sub>2</sub>/SnO<sub>2</sub> ...
2,319,478
Effects of membrane relaxation rate on performance of pilot-scale membrane aerated biofilm reactors treating domestic wastewater.
The membranes of a Membrane Aerated Biofilm Reactor (MABR) function as bubble-less air diffusers and bio-carriers. Recent bench-scale experiments reported that the shape of membranes influenced the oxygen transfer and utilization rates, which in turn affected the pollutant removal performance of the MABR. In this study...
2,319,479
Effects of temperature and HRT on biogas production in moving and fixed bed of a novel upflow anaerobic hybrid (UAHB) reactor.
The upflow anaerobic hybrid (UAHB) reactor combines the advantages of a upflow anaerobic sludge blanket (UASB-type) reactor and an anaerobic filter in a single compartment. A novel configuration of the UAHB reactor, composed of two three-phase separators (3PHS), was proposed to evaluate the biogas production in the mov...
2,319,480
Effective treatment of acid mine drainage using a combination of MgO-nanoparticles and a series of constructed wetlands planted with Vetiveria zizanioides: A hybrid and stepwise approach.
In this novel study, acid mine drainage (AMD) was treated using a hybrid approach comprising a nano-and-biotic system synergistically integrated in a step-wise and modular fashion. Specifically, the treatment chains were made up of different stages, which comprise, neutralization using activated magnesite or MgO-nanopa...
2,319,481
The impact of bioretention column internal water storage underdrain height on denitrification under continuous and transient flow.
Internal water storage (IWS), a below-grade saturated layer, is a bioretention design component created by adjusting the underdrain outlet elevation. Anaerobic conditions and the presence of a carbon source in IWS facilitates denitrification. Yet it remains unclear how underdrain height within the IWS impacts nitrate (...
2,319,482
Could Perimenopausal Estrogen Prevent Breast Cancer? Exploring the Differential Effects of Estrogen-Only Versus Combined Hormone Replacement Therapy.
Breast cancer is the commonest cancer among women in the western world, accounting for up to 30% of all cancers in women. There is a long-standing controversy about the potential link to hormone replacement therapy (HRT), with large observational studies suggesting that HRT increases the risk, while the Women's Health ...
2,319,483
Effect of Self-Made TiO<sub>2</sub> Nanoparticle Size on the Performance of the PVDF Composite Membrane in MBR for Landfill Leachate Treatment.
The pollutant composition of landfill leachate is complex, and pollutant concentrations change greatly. Moreover, landfill leachates can easily penetrate into the soil and eventually pollute the ground water, which can cause environmental pollution and threaten human health. At present, landfill leachate treatment tech...
2,319,484
Application of Sol-Gels for Treatment of Gynaecological Conditions-Physiological Perspectives and Emerging Concepts in Intravaginal Drug Delivery.
Approaches for effective and sustained drug delivery to the female reproductive tract (FRT) for treating a range of gynaecological conditions remain limited. The development of versatile delivery platforms, such as soluble gels (sol-gels) coupled with applicators/devices, holds considerable therapeutic potential for gy...
2,319,485
Nitrate removal under low carbon to nitrogen ratio by modified corn straw bioreactor: Optimization and possible mechanism.
<b>ABSTRACT</b>The removal of nitrate (NO<sub>3</sub><sup>-</sup>-N) from water bodies under the conditions of poor nutrition and low carbon to nitrogen (C/N) ratio is a widespread problem. In this study, modified corn stalk (CS) was used to immobilize <i>Burkholderia</i> sp. CF6 with cellulose-degrading and denitrifyi...
2,319,486
Characteristics of organic removal for supermarket wastewater treatment with an anaerobic baffled reactor and efficacy evaluation of changing HRT.
An anaerobic baffled reactor (ABR) is one of the useful wastewater treatment technologies, but the knowledge about its treatment performance for actual wastewater with load fluctuation is limited. The organic removal performance of an ABR for treating supermarket wastewater was evaluated. The ABR, which consisted of ei...
2,319,487
Hormonal Replacement Treatment for Frozen-Thawed Embryo Transfer With or Without GnRH Agonist Pretreatment: A Retrospective Cohort Study Stratified by Times of Embryo Implantation Failures.
To evaluate the efficacy of the long-acting gonadotropin-releasing hormone agonist (GnRH-a) administration before hormone replacement treatment for frozen-thawed embryo transfer in women with different times of embryo implantation failures.</AbstractText>A retrospective cohort study was performed between January 2015 a...
2,319,488
Fostering the valorization of organic wastes into carboxylates by a computer-aided design tool.
The carboxylate platform has the potential to constitute an outstanding opportunity for converting organic wastes into chemicals and other value-added products within a circular economy framework. However, its development is still hampered by technological and financial constraints due to difficulties at forecasting th...
2,319,489
Innovative co-production of polyhydroxyalkanoates and methane from broken rice.
Broken rice, a low-cost starchy residue of the rice industry, can be an interesting substrate to reduce the polyhydroxyalkanoates (PHAs) production cost. However, since the most common PHAs-producing strains lack amylases, this waste must be firstly hydrolysed by additional commercial enzymes. In this work, the acidoge...
2,319,490
Balancing acidogenesis and methanogenesis metabolism in thermophilic anaerobic digestion of food waste under a high loading rate.
Achieving a metabolic balance between volatile fatty acid (VFA) production and conversion is a standing challenge in high temperature and organic loading rate anaerobic digestion. A thermophilic anaerobic digestion reactor fed with food waste was therefore operated for 230 days to investigate metabolic performance in a...
2,319,491
Population-genetic Aspects of Breast Cancers and Association with Rh Factor in Selected Sample.
Breast cancer in women is the second most common and accounts for approximately 18% of all malignant tumors in women worldwide. The etiology of breast cancer is not clear enough. Starting from the assumption that the manifestation of breast cancer may have a multifactorial model, this article compares the population-ge...
2,319,492
Female Reproductive Factors and Incidence of Nontuberculous Mycobacterial Pulmonary Disease Among Postmenopausal Women in Korea.
There are conflicting results regarding endogenous estrogen exposure and risk of incident nontuberculous mycobacterial pulmonary disease (NTM-PD). In addition, evidence on impact of hormone replacement therapy (HRT) on risk of NTM-PD is lacking. This study aimed to evaluate the impacts of endogenous estrogen exposure a...
2,319,493
Association between pharmaceutical modulation of oestrogen in postmenopausal women in Sweden and death due to COVID-19: a cohort study.
Determine whether augmentation of oestrogen in postmenopausal women decreases the risk of death following COVID-19.</AbstractText>Nationwide registry-based study in Sweden based on registries from the Swedish Public Health Agency (all individuals who tested positive for SARS-CoV-2); Statistics Sweden (socioeconomical v...
2,319,494
Effectiveness of Exogenous Fe<sup>2+</sup> on Nutrient Removal in Gravel-Based Constructed Wetlands.
A group of microcosm-scale unplanted constructed wetlands (CWs) were established to evaluate the effectiveness of exogenous Fe<sup>2+</sup> addition on ammonium nitrogen (NH<sub>4</sub><sup>+</sup>-N), nitrate nitrogen (NO<sub>3</sub><sup>-</sup>-N), and total phosphorus (TP) removal. The addition of Fe<sup>2+</sup> co...
2,319,495
Microbial induced calcium precipitation based anaerobic immobilized biofilm reactor for fluoride, calcium, and nitrate removal from groundwater.
In this study, the anaerobic quartz sand fixed biofilm reactor containing Cupriavidus sp. W12 was established to simultaneously remove calcium (Ca<sup>2+</sup>), fluoride (F<sup>-</sup>) and nitrate (NO<sub>3</sub><sup>-</sup>N) from groundwater. After 84 days of continuous operation, the optimum operating parameters a...
2,319,496
Presence of endometrial nucleolar channel systems at the time of frozen embryo transfer in hormone replacement cycles with successful implantation.
To detect nucleolar channel systems (NCSs) in cells in endometrial aspirations obtained immediately before embryo transfer during blastocyst hormone replacement therapy-frozen embryo transfer (HRT-FET) cycles without affecting implantation.</AbstractText>Prospective case series.</AbstractText>University-affiliated fert...
2,319,497
Evaluation of Optic Nerve Head Parameters and Electro-Physiology Among Breast Cancer Patients on Tamoxifen.
Introduction To evaluate if early tamoxifen toxicity can be detected by comparing pre-and post-treatment optic nerve head parameters and visual function using Heidelberg Retinal Tomograph III (HRT III) and Pattern Visual Evoked Potential (Pattern VEP). Method This is a prospective study involving 76 eyes of 38 breast c...
2,319,498
Nitrogen Advanced Treatment of Urban Sewage by Denitrification Deep-Bed Filter: Removal Performance and Metabolic Pathway.
This study aimed to explore the performance of denitrification deep-bed filter (DN-DBF) to treat municipal sewage for meeting a more stringent discharge standard of total nitrogen (TN) (10.0 mg L<sup>-1</sup>). A lab-scale DN-DBF was conducted to optimize operation parameters and reveal the microbiological mechanism fo...
2,319,499
Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K/AKT signaling pathway.
Moxibustion, a common therapy in traditional Chinese medicine, has potential benefits for treating decreased ovarian reserve (DOR). The present study investigates the protective effect of moxibustion in a rat model of DOR and explores the possible mechanisms.</AbstractText>Sixty-four female Sprague-Dawley rats were ran...