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2,325,700 | Endoscopic management of a choroid plexus cyst of the third ventricle: case report and documentation of dynamic behavior. | The aim of this study is to document the dynamic behavior of a choroid plexus cyst of the third ventricle. Although these lesions may float freely within the ventricle leading to intermittent obstruction of the cerebrospinal fluid (CSF) circulation at variable points in a single patient, such a phenomenon has only been... |
2,325,701 | The effects of vasoactive peptide urocortin 2 on hemodynamics in spontaneous hypertensive rat and the role of L-type calcium channel and CRFR2. | Urocortin (UCN) is a newly identified vascular-active peptide that has been shown to reverse cardiovascular remodeling and improve left ventricular (LV) function. The effects and mechanism of urocortin 2 (UCN2) in vivo on the electrical remodeling of left ventricle and the hemodynamics of hypertensive objectives have n... |
2,325,702 | Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomas. | Bevacizumab is widely used for treatment of high-grade gliomas and other malignancies. Because bevacizumab has been shown to be associated with neurocognitive decline, this study is designed to investigate whether prolonged treatment with bevacizumab is also associated with brain atrophy. We identified 12 high-grade gl... |
2,325,703 | Exercise-induced neuroprotection in the spastic Han Wistar rat: the possible role of brain-derived neurotrophic factor. | Moderate aerobic exercise has been shown to enhance motor skills and protect the nervous system from neurodegenerative diseases, like ataxia. Our lab uses the spastic Han Wistar rat as a model of ataxia. Mutant rats develop forelimb tremor and hind limb rigidity and have a decreased lifespan. Our lab has shown that exe... |
2,325,704 | External cortical landmarks and measurements for the temporal horn: Anatomic study with application to surgery of the temporal lobe. | The location of the temporal horn is important to neurosurgeons during procedures such as amygdalohippocampectomy and intraventricular electrode placement for temporal lobe seizure monitoring. However, sometimes the temporal horn is difficult to localize, especially without neuronavigation. The authors aimed to better ... |
2,325,705 | Ghrelin regulates phasic dopamine and nucleus accumbens signaling evoked by food-predictive stimuli. | Environmental stimuli that signal food availability hold powerful sway over motivated behavior and promote feeding, in part, by activating the mesolimbic system. These food-predictive cues evoke brief (phasic) changes in nucleus accumbens (NAc) dopamine concentration and in the activity of individual NAc neurons. Phasi... |
2,325,706 | Integrated annotation and analysis of in situ hybridization images using the ImAnno system: application to the ear and sensory organs of the fetal mouse. | An in situ hybridization (ISH) study was performed on 2000 murine genes representing around 10% of the protein-coding genes present in the mouse genome using data generated by the EURExpress consortium. This study was carried out in 25 tissues of late gestation embryos (E14.5), with a special emphasis on the developing... |
2,325,707 | Function and regulation of Rnd proteins in cortical projection neuron migration. | The mammalian cerebral cortex contains a high variety of neuronal subtypes that acquire precise spatial locations and form long or short-range connections to establish functional neuronal circuits. During embryonic development, cortical projection neurons are generated in the areas lining the lateral ventricles and the... |
2,325,708 | Comparison of a modified mid-coronal sectioning technique and Wilson's technique when conducting eye and brain examinations in rabbit teratology studies. | There are two methods used when examining fetal rabbit eyes and brain in teratology studies. One method employs prior fixation before serial sectioning (Wilson's technique) and the other uses fresh tissue (mid-coronal sectioning).</AbstractText>We modified the mid-coronal sectioning technique to include removal of eyes... |
2,325,709 | Intracranial Fungal Granulomas: A Single Institutional Clinicopathologic Study of 66 Patients and Review of the Literature. | Fungal granulomas of the central nervous system are rare and have a high rate of mortality and morbidity, irrespective of treatment. The authors report their experience of managing 66 patients during 15 years and discuss the clinical, radiological, surgical, and pathologic findings. This series is among the largest rep... |
2,325,710 | Surgical management of non-communicating hydrocephalus in patients: meta-analysis and comparison of endoscopic third ventriculostomy and ventriculoperitoneal shunt. | We performed a meta-analysis of reported series of endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) for non-communicating hydrocephalus to determine whether comparisons between the outcomes in ETV and VPS approaches are valid.</AbstractText>Online databases were searched for articles reportin... |
2,325,711 | Olfactory and cortical projections to bulbar and hippocampal adult-born neurons. | New neurons are continually generated in the subependymal layer of the lateral ventricles and the subgranular zone of dentate gyrus during adulthood. In the subventricular zone, neuroblasts migrate a long distance to the olfactory bulb where they differentiate into granule or periglomerular interneurons. In the hippoca... |
2,325,712 | Telovelar Approach to Fourth Ventricle Tumors: Highlights and Limitations. | Fourth ventricle tumors have been traditionally approached by opening the cerebellar vermis. The "telovelar" approach is an alternative approach performed through the cerebellomedullary fissure to gain access to the fourth ventricle, avoiding neural tissue damage. We describe our experience with this approach and predi... |
2,325,713 | Effect of cholecalciferol replacement on vascular calcification and left ventricular mass index in dialysis patients. | The aim of this study was to determine the effect of oral cholecalciferol treatment on vascular calcification, left ventricular mass index (LVMI) and other cardiac functions in dialysis patients.</AbstractText>A six-month course of oral cholecalciferol treatment was recommended to dialysis patients with vitamin D insuf... |
2,325,714 | Repetitive mild traumatic brain injury induces ventriculomegaly and cortical thinning in juvenile rats. | Traumatic brain injury (TBI) most frequently occurs in pediatric patients and remains a leading cause of childhood death and disability. Mild TBI (mTBI) accounts for nearly 75% of all TBI cases, yet its neuropathophysiology is still poorly understood. While even a single mTBI injury can lead to persistent deficits, rep... |
2,325,715 | The outer subventricular zone and primate-specific cortical complexification. | Evolutionary expansion and complexification of the primate cerebral cortex are largely linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured germinal zone that generates the expanded primate supragranular layers. The primate OSVZ departs from rodent germinal zones in that it includes a ... |
2,325,716 | Pontine Tegmental Cap Dysplasia: MR Evaluation of Vestibulocochlear Neuropathy. | Pontine tegmental cap dysplasia (PTCD) is recently recognized as a rare congenital brain stem malformation with typical neuroimaging hallmarks of ventral pontine hypoplasia and vaulted pontine tegmentum projecting into the fourth ventricle. PTCD patients also demonstrate variable cranial neuropathy with predilection fo... |
2,325,717 | RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. | Adult neural stem cell (aNSC) activity is tuned by external stimuli through the recruitment of transcription factors. This study examines the RE1 silencing transcription factor (REST) in neural stem/progenitor cells isolated from the subventricular zone of adult mouse brain and provides the first extensive characteriza... |
2,325,718 | Differential regional and cellular distribution of TFF3 peptide in the human brain. | TFF3 is a member of the trefoil factor family (TFF) predominantly secreted by mucous epithelia. Minute amounts are also expressed in the immune system and the brain. In the latter, particularly the hypothalamo-pituitary axis has been investigated in detail in the past. Functionally, cerebral TFF3 has been reported to b... |
2,325,719 | Altered urinary sodium excretion response after central cholinergic and adrenergic stimulation of adult spontaneously hypertensive rats. | In this study, we hypothesized that blunting of the natriuresis response to intracerebroventricularly (i.c.v.) microinjected cholinergic and adrenergic agonists is involved in the development of hypertension in spontaneously hypertensive rats (SHR). We evaluated the effect of i.c.v. injection of cholinergic and noradre... |
2,325,720 | Schizencephaly-diagnostics and clinical dilemmas. | Schizencephaly is an uncommon congenital disorder of cerebral cortical development. The defect is characterized by the presence of a cleft in the brain extending from the surface of the pia mater to the cerebral ventricles. The margins of the cleft are lined with heterotropic, dysplastic gray matter. The causes of schi... |
2,325,721 | Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity. | Premature birth is a major risk factor for multiple brain pathologies, notably periventricular leukomalacia (PVL), which is distinguished by bilateral necrosis of neural tissue around the ventricles and a sequela of neurological disturbances. The 2 hallmarks of brain pathologies of prematurity are a restricted gestatio... |
2,325,722 | Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain. | Luminescent semiconductor ∼9.5 nm nanoparticles (quantum dots: QDs) have intrinsic physiochemical and optical properties which enable us to begin to understand the mechanisms of nanoparticle mediated chemical/drug delivery. Here, we demonstrate the ability of CdSe/ZnS core/shell QDs surface functionalized with a... |
2,325,723 | The conundrum of arterial stiffness, elevated blood pressure, and aging. | Isolated systolic hypertension is a major health burden that is expanding with the aging of our population. There is evidence that central arterial stiffness contributes to the rise in systolic blood pressure (SBP); at the same time, central arterial stiffening is accelerated in patients with increased SBP. This bidire... |
2,325,724 | Toll-like receptor-2 deficiency induces schizophrenia-like behaviors in mice. | Dysregulation of the immune system contributes to the pathogenesis of neuropsychiatric disorders including schizophrenia. Here, we demonstrated that toll-like receptor (TLR)-2, a family of pattern-recognition receptors, is involved in the pathogenesis of schizophrenia-like symptoms. Psychotic symptoms such as hyperloco... |
2,325,725 | Improved nutrition delivery and nutrition status in critically ill children with heart disease. | This initiative sought to improve nutrition delivery in critically ill children with heart disease admitted to the cardiac ICU (CICU) and neonates undergoing stage 1 palliation (S1P) for single-ventricle physiology through interdisciplinary team interventions. Specific goals were increased caloric and protein delivery ... |
2,325,726 | Cerebral Rosai-Dorfman disease. | Sinus histiocytosis (Rosai-Dorfman disease) with massive lymphadenopathy is a rare nonneoplastic and nonlangerhans cell proliferation disorder of the histiocytes. Extranodal location with or without lymphadenopathy occurs in about 40 % of the cases. Intracranial location is rare in children often mimicking meningiomas.... |
2,325,727 | Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain. | Every cell type is characterized by a specific transcriptional profile together with a unique epigenetic landscape. Reprogramming factors such as Oct4, Klf4, Sox2 and c-Myc enable somatic cells to change their transcriptional profile and convert them to pluripotent cells. Small molecules such as BIX-01294, Bay K8644, R... |
2,325,728 | Choroid plexus papilloma of posterior third ventricle: A case report and review of literature. | Choroid plexus papillomas (CPPs) are rare intracranial neoplasms, especially in the third ventricle. The most common site of presentation of these lesions is in the fourth ventricle in adults and lateral ventricles in children. We report a male child with a posterior third ventricular CPP who presented with the symptom... |
2,325,729 | Single port microsurgical technique for excision of third ventricular colloid cysts. | Colloid cysts are benign space-occupying lesions that account for 0.5-1.0% of brain tumors and arise from the velum interpositum or the choroid plexus of the third ventricle.</AbstractText>We are describing a modified surgical technique that combines the positive attributes of being minimalistic, while retaining the ef... |
2,325,730 | Early experience in endoscopic management of massive intraventricular hemorrhage with literature review. | Massive intraventricular hemorrhage (IVH) is nearly always associated with hydrocephalus and is often treated with prolonged external ventricular drainage (EVD); however this procedure can lead to bacterial ventriculitis and meningitis, which can worsen the clinical outcomes. Endoscopic burr hole surgery to remove the ... |
2,325,731 | Effect of nicotine on neuronal dysfunction induced by intracerebroventricular infusion of amyloid-β peptide in rats. | The aim of the study was to investigate the effects of nicotine on learning and memory deficits induced by intracerebroventricular infusion of amyloid-β peptide (Aβ) in rats.</AbstractText>Neuronal dysfunction in rats was induced by an infusion of Aβ(1-42) (20 µg/body, over 3 days) into right ven... |
2,325,732 | Plexogenic arteriopathy in broiler lungs: Evaluation of line, age, and sex influences. | Plexiform lesions form in the terminal pulmonary arterioles of human patients suffering from prolonged pulmonary arterial hypertension. Plexiform lesions also develop in broiler lungs, but lesion incidences are not strongly correlated with sustained pulmonary hypertension as reflected by right to total ventricular weig... |
2,325,733 | TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport. | The diffusion of materials from systemic circulation to the central nervous system (CNS) is restricted by the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). Choroid plexus epithelial cells (CPECs) of the brain ventricles constitute the BCSFB and regulate the infiltration of plasma proteins... |
2,325,734 | The electrical activity of hippocampal pyramidal neuron is subjected to descending control by the brain orexin/hypocretin system. | The hippocampus receives sparse orexinergic innervation from the lateral hypothalamus and expresses a high level of orexin receptor. The function of orexin receptor in the regulation of hippocampal neural activity has never been investigated. In this study, in vivo single unit recording was performed in urethane-anesth... |
2,325,735 | Association between ventricular volume measures and pulsatile and static intracranial pressure scores in non-communicating hydrocephalus. | In non-communicating hydrocephalus (HC), enlarged cerebral ventricles are often thought to reflect increased intracranial pressure (ICP) or increased pulsatile ICP. The present study was undertaken to explore the association between ventricular volume measures and pulsatile or static ICP scores in patients with non-com... |
2,325,736 | Early outcome of combined endoscopic third ventriculostomy and choroid plexus cauterization in childhood hydrocephalus. | Although shunts have been the mainstay in treating hydrocephalus over the past 5 decades, the use of endoscopic techniques in addressing this disorder in children offers both the neurosurgeon and the patient a unique opportunity to avoid shunting and its attendant complications. The combination of endoscopic third vent... |
2,325,737 | Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence. | Interstitial fluid (ISF) surrounds the parenchymal cells of the brain and spinal cord while cerebrospinal fluid (CSF) fills the larger spaces within and around the CNS. Regulation of the composition and volume of these fluids is important for effective functioning of brain cells and is achieved by barriers that prevent... |
2,325,738 | Gadd45b is a novel mediator of neuronal apoptosis in ischemic stroke. | Apoptosis plays an essential role in ischemic stroke pathogenesis. Research on the process of neuronal apoptosis in models of ischemic brain injury seems promising. The role of growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) in brain ischemia has not been fully examined to date. This study aims to inve... |
2,325,739 | Cell-to-cell diffusion of glucose in the mammalian heart is disrupted by high glucose. Implications for the diabetic heart. | The cell-to-cell diffusion of glucose in heart cell pairs isolated from the left ventricle of adult Wistar Kyoto rats was investigated. For this, fluorescent glucose was dialyzed into one cell of the pair using the whole cell clamp technique, and its diffusion from cell-to-cell was investigated by measuring the fluores... |
2,325,740 | The subventricular zone in the immature piglet brain: anatomy and exodus of neuroblasts into white matter after traumatic brain injury. | Stimulation of postnatal neurogenesis in the subventricular zone (SVZ) and robust migration of neuroblasts to the lesion site in response to traumatic brain injury (TBI) is well established in rodent species; however, it is not yet known whether postnatal neurogenesis plays a role in repair after TBI in gyrencephalic s... |
2,325,741 | Fluid area measurements in the posterior fossa at 11-13 weeks in normal fetuses and fetuses with open spina bifida. | To measure the area of the intracranial translucency (IT) (syn: 4th ventricle) and the future cisterna magna (CM) in normal fetuses and to compare with fetuses with open spina bifida.</AbstractText>In the midsagittal plane of the face of 220 fetuses between 11 and 13 weeks' gestation, the areas of the IT and CM were me... |
2,325,742 | Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep. | Loss-of-function mutations in genes encoding kisspeptin or neurokinin B (NKB) or their receptors cause infertility. NKB is coproduced in kisspeptin neurons in the arcuate nucleus (ARC), and these neurons also produce the NKB receptor (NK3R), allowing autosynaptic function. We tested the hypothesis that NKB action in AR... |
2,325,743 | Intraventricular glioblastoma multiforme: Case report. | Glioblastoma multiforme (GBM) is the most common primary brain tumor, but pure intraventricular location is extremely rare for GBM in neurosurgical practice. To our knowledge, there are only 19 reported cases to date. We present an additional case of intraventricular GBM with detailed clinical course, radiological and ... |
2,325,744 | Embolization of left atrial appendage closure devices: A systematic review of cases reported with the watchman device and the amplatzer cardiac plug.<Pagination><StartPage>128</StartPage><EndPage>135</EndPage><MedlinePgn>128-35</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/ccd.25891</ELocation... | Peculiarities of deformity of the left ventricle (LV) walls were studied in 93 patients in various variants of hypertrophic cardiomyopathy (HCMP). In accordance to complex echocardiography data, including vector-echocardiography, in HCMP the deformity grade and quantity of the affected segments of the LV myocardium hav... |
2,325,745 | Hydrocephalus due to Membranous Obstruction of Magendie's Foramen. | We report a case of non communicating hydrocephalus due to membranous obstruction of Magendie's foramen. A 37-year-old woman presented with intracranial hypertension symptoms caused by the occlusion of Magendie's foramen by a membrane probably due to arachnoiditis. As far as the patient's past medical history is concer... |
2,325,746 | Cryptococcal brainstem abscess mimicking brain tumors in an immunocompetent patient. | Usually fungal infections caused by opportunistic and pathogenic fungi had been an important cause of morbidity and mortality among immunocompromised patients. However clinical data and investigations for immunocompetent pathogenic fungal infections had been rare and neglected into clinical studies. Especially Cryptoco... |
2,325,747 | Intracranial multiple germ cell tumors: a case report and review of literature. | Intracranial multiple germ cell tumors (GCTs) are rare. In this article, we reported a case of intracranial multiple GCTs in an 18-year-old boy with symptoms of psychosis for 8 months also. Tumors in the pineal, sellar region, corpus callosum, bilateral lateral ventricles and fourth ventricle were confirmed by enhanced... |
2,325,748 | Inspiration is the major regulator of human CSF flow. | The mechanisms behind CSF flow in humans are still not fully known. CSF circulates from its primary production sites at the choroid plexus through the brain ventricles to reach the outer surface of the brain in the subarachnoid spaces from where it drains into venous bloodstream and cervical lymphatics. According to a ... |
2,325,749 | Treatment strategies for huge central neurocytomas. | Central neurocytomas (CNs), initially asymptomatic, sometimes become huge before detection. We described and analyzed the clinical, radiological, operational and outcome data of 13 cases of huge intraventricular CNs, and discussed the treatment strategies in this study. All huge CNs (n=13) in our study were located in ... |
2,325,750 | Characterization of samhd1 morphant zebrafish recapitulates features of the human type I interferonopathy Aicardi-Goutières syndrome. | In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe form of Aicardi-Goutières syndrome (AGS), an inherited inflammatory-mediated encephalopathy characterized by increased type I IFN activity and upregulation of IFN-stimulated genes (ISGs). In particular, SAMHD1-related AGS is associated ... |
2,325,751 | [Hypothesis of cerebrospinal fluid formation and absorption: from the clinical viewpoint of idiopathic normal pressure hydrocephalus]. | The morphological features of disproportionately enlarged subarachnoid-space hydrocephalus (DESH), the core type of idiopathic normal pressure hydrocephalus, can not be explained by the classical theory of CSF absorption at the arachnoid villi and the hypothesis of CSF flow blocking at the convexity subarachnoid spaces... |
2,325,752 | [A case of ganglioglioma extended to the lateral ventricle and associated with neurofibromatosis type 1]. | We encountered a rare case of intraventricular ganglioglioma associated with neurofibromatosis type 1. A 42-year-old woman presented with a feeling of heaviness of the head and dizziness. She was diagnosed with neurofibromatosis type 1 because she had multiple subcutaneous neurofibromas and café au lait spots. On ... |
2,325,753 | [Optimal imaging parameters and the advantage of cerebrospinal fluid flow image using time-spatial labeling inversion pulse at 3 tesla magnetic resonance imaging: comparison of image quality for 1.5 tesla magnetic resonance imaging]. | Cerebrospinal fluid (CSF) imaging by time-spatial labeling inversion pulse (Time-SLIP) technique is labeled by CSF with a selective inversion recovery (IR) pulse as internal tracer, thus making it possible to visualize CSF dynamics non-invasively. The purpose of this study was to clarify labeled CSF signals during vari... |
2,325,754 | Consistent nuclear expression of thyroid transcription factor 1 in subependymal giant cell astrocytomas suggests lineage-restricted histogenesis. | Thyroid transcription factor 1 (TTF-1) is encoded by the NKX2-1 homeobox gene. Besides specifying thyroid and pulmonary organogenesis, it is also temporarily expressed during embryonic development of the ventral forebrain. We recently observed widespread immunoreactivity for TTF-1 in a case of subependymal giant cell a... |
2,325,755 | [Fetal therapy--evaluation of ventriculo-amniotic shunts in the treatment of hydrocephalus]. | The aim of the study was to establish optimal diagnostic and therapeutic scheme and to assess the efficacy of intrauterine therapy of hydrocephalus.</AbstractText>The study was carried out between 1992-2012 on the total of 222 fetuses with hydro- cephalus, using Orbis-Sigma and ACCU-Flow valves (168 cases) and Cook8 sh... |
2,325,756 | Inferior cerebellar hypoplasia resembling a Dandy-Walker-like malformation in purebred Eurasier dogs with familial non-progressive ataxia: a retrospective and prospective clinical cohort study. | Cerebellar malformations can be inherited or caused by insults during cerebellar development. To date, only sporadic cases of cerebellar malformations have been reported in dogs, and the genetic background has remained obscure. Therefore, this study`s objective was to describe the clinical characteristics, imaging feat... |
2,325,757 | Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats. | Although we previously demonstrated that activation of central nervous system (CNS) melanocortin3/4 receptors (MC3/4R) play a key role in blood pressure (BP) regulation, especially in spontaneously hypertensive rats (SHRs), the importance of hindbrain MC4R is still unclear.</AbstractText>In the present study, we examin... |
2,325,758 | Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. | Insulin detemir (DET) reduces glycemia comparably to other long-acting insulin formulations but causes less weight gain. Insulin signaling in the brain is catabolic, reducing food intake. We hypothesized that DET reduces weight gain, relative to other insulins, owing to increased transport into the central nervous syst... |
2,325,759 | Long-term supratentorial brain structure and cognitive function following cerebellar tumour resections in childhood. | The cerebellum is connected to extensive regions of the cerebrum, and cognitive deficits following cerebellar lesions may thus be related to disrupted cerebello-cerebral connectivity. Moreover, early cerebellar lesions could affect distal brain development, effectively inducing long-term changes in brain structure and ... |
2,325,760 | Postoperative hyperthermia after resection of a seminoma from the thalamus and third ventricle. | Hyperthermia is relatively common in inpatients, but hyperthermia occurring in the immediate postoperative period after undergoing neurosurgery has some unique characteristics. This case report concerns a patient who developed immediate postoperative hyperthermia up to 39.3°C (the axillary temperature) in the post... |
2,325,761 | Inhibition of synaptophysin ubiquitination may improve the intelligent drop due to high glucose and hypoxia. | Synaptophysin (SYP) is a synaptic vesicle membrane protein and involved in the release of neurotransmitters, synaptic plasticity, and formation and recycling of synaptic vesicles. SYP may serve as a specific marker of synaptic proteins. Our results showed high glucose and hypoxia could significantly impair the intellig... |
2,325,762 | The relationship between left ventricle myocardial performance index of healthy women and geographical factors. | The study focused on the relationship between geographical factors and left ventricular myocardial performance index (MPI)reference value, analyed the different distribution of MPI, and then provided a scientific basis for clinical examination. This study collected MPI reference values of 2545 healthy women from 91 cit... |
2,325,763 | In vivo imaging of microfluidic-produced microbubbles. | Microfluidics-based production of stable microbubbles for ultrasound contrast enhancement or drug/gene delivery allows for precise control over microbubble diameter but at the cost of a low production rate. In situ microfluidic production of microbubbles directly in the vasculature may eliminate the necessity for high ... |
2,325,764 | Intraventricular hemorrhage expansion in patients with spontaneous intracerebral hemorrhage. | To evaluate whether delayed appearance of intraventricular hemorrhage (dIVH) represents an independent entity from intraventricular hemorrhage (IVH) present on admission CT or is primarily related to the time interval between symptom onset and admission CT.</AbstractText>A total of 282 spontaneous intracerebral hemorrh... |
2,325,765 | Optimal treatment of leptomeningeal spread in glioblastoma: analysis of risk factors and outcome. | Glioblastoma (GBM) is the most common and malignant brain tumor in adults. Despite therapeutic advances, almost all patients eventually experience tumor recurrence. Leptomeningeal spread (LMS) is not a rare condition of recurrence. However, the standard management protocol of LMS has not been established. The aim of th... |
2,325,766 | Smart stylet: the development and use of a bedside external ventricular drain image-guidance system. | Placement accuracy of ventriculostomy catheters is reported in a wide and variable range. Development of an efficient image-guidance system may improve physician performance and patient safety.</AbstractText>We evaluate the prototype of Smart Stylet, a new electromagnetic image-guidance system for use during bedside ve... |
2,325,767 | Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus. | The present study describes for the first time the neural expression and distribution of UGS148, a protein encoded by the RIKEN cDNA63330403K07 gene that has been shown to be prominently and characteristically expressed in neural stem cells (NSCs). Based on its molecular structure, UGS148 is an intracellular protein ex... |
2,325,768 | Practical aspects of volume control in chronic kidney disease using whole body bioimpedance. | Fluid status is an independent predictor of mortality in dialysis patients. Current methods of fluid assessment have several limitations.</AbstractText>An ideal method should be cheap, portable, easy to perform without extensive training, reproducible and determines patients' excess or deficit of total body water. Bioi... |
2,325,769 | Fibronectin changes in eosinophilic meningitis with blood-CSF barrier disruption. | Fibronectin, which is present at relatively low levels in healthy central nervous systems (CNS), shows increased levels in meningitis. In this study, fibronectin processing was correlated with the increased permeability of the blood-cerebrospinal fluid (CSF) barrier as well as with the formation of eosinophil infiltrat... |
2,325,770 | Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice. | Neurones in the arcuate nucleus that express neurokinin B (NKB), kisspeptin and dynorphin (KNDy) play an important role in the reproductive axis. Oestradiol modulates the gene expression and somatic size of these neurones, although there is limited information available about whether their dendritic structure, a correl... |
2,325,771 | LXR agonist T0901317-Induced hyperlipidemia does not lead to lipid accumulation in the rat heart. | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Liver X receptors (LXRα and LXRβ) are ligand-activated transcription factors that regulate expression of genes involved in lipid and cholesterol metabolism. LXR expression has been identified in human and rodent cardiac tissue, however, its role ... |
2,325,772 | Porohyperelastic anatomical models for hydrocephalus and idiopathic intracranial hypertension. | Brain deformation can be seen in hydrocephalus and idiopathic intracranial hypertension (IIH) via medical images. The phenomenology of local effects, brain shift, and raised intracranial pressure and herniation are textbook concepts. However, there are still uncertainties regarding the specific processes that occur whe... |
2,325,773 | Reopening of an obstructed third ventriculostomy: long-term success and factors affecting outcome in 215 infants. | The role of reopening an obstructed endoscopic third ventriculostomy (ETV) as treatment for ETV failure is not well defined. The authors studied 215 children with ETV closure who underwent successful repeat ETV to determine the indications, long-term success, and factors affecting outcome.</AbstractText>The authors ret... |
2,325,774 | Uncontrolled diabetes resulting in diabetic cardiomyopathy in a young male patient and eventually presenting with a stroke. | Diabetic cardiomyopathy (DCP) is defined as the cardiovascular damage present in diabetes patients, which is characterized by myocardial dilatation and hypertrophy, as well as a decrease in the systolic and diastolic function of the left ventricle, and its presence is independent of the coexistence of ischemic heart di... |
2,325,775 | Bilateral assymetric epidural hematoma. | Acute bilateral extradural hematoma is a rare presentation of head trauma injury. In sporadic cases, they represent 0.5-10% of all extradural hematomas. However, higher mortality rates have been reported in previous series.</AbstractText>The authors described the case of a 28-year-old male presenting head injury, comat... |
2,325,776 | Symptomatic foramen of Magendie arachnoid cyst in an elderly patient. | Arachnoid cysts (ACs) are congenital anomalies of the central nervous system and arise in virtually all locations where the arachnoid membrane exists. Posterior fossa ACs are considered to develop in the posterior aspect of the rhombencephalic roof plate and do not communicate freely with the fourth ventricle or perime... |
2,325,777 | An uncommon localization of a giant hydatid cyst presenting with cardiac tamponade. | Cardiac involvement in hydatid cyst disease is a rare manifestation and may remain asymptomatic for years. The location of the cyst determines the presentation. In this report, we present a case of hydatid cyst presenting with massive pericardial effusion, right ventricle compression leading to cardiac tamponade. The d... |
2,325,778 | The dynamics of physical exercise-induced increases in thalamic and abdominal temperatures are modified by central cholinergic stimulation. | Evidence has shown that brain and abdominal (T abd) temperatures are regulated by distinct physiological mechanisms. Thus, the present study examined whether central cholinergic stimulation would change the dynamics of exercise-induced increases in T abd and thalamic temperature (T thal), an index of brain temperature.... |
2,325,779 | A pediatric case of Bickerstaff's brainstem encephalitis. | Bickerstaff's brainstem encephalitis is characterized by ophthalmoplegia, ataxia, and disturbance of consciousness. It is similar to Miller Fisher syndrome, a variant of Guillain-Barre syndrome, in that they share features such as ophthalmoplegia and ataxia. The difference is that patients with Bickerstaff's brainstem ... |
2,325,780 | S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. | Accumulating genetic evidence suggests that schizophrenia (SZ) is associated with individually rare copy number variations (CNVs) of diverse genes, often specific to single cases. However, the causality of these rare mutations remains unknown. One of the rare CNVs found in SZ cohorts is the duplication of Synaptic Scaf... |
2,325,781 | Telo-velar approach to fourth-ventricle tumours: how I do it. | The "telo-velar" approach is an alternative to cerebellar splitting to gain access to the fourth ventricle through the so-called cerebello-medullary fissure (CMF).</AbstractText>In this approach, the CMF is exposed and access to the ventricle is obtained by incising the tela chorioidea and inferior medullary velum. Thi... |
2,325,782 | Three-dimensional structure of the intercalated disc reveals plicate domain and gap junction remodeling in heart failure. | The intercalated disc (ICD) orchestrates electrochemical and mechanical communication between neighboring cardiac myocytes, properties that are perturbed in heart failure (HF). Although structural data from transmission electron microscopy two-dimensional images have provided valuable insights into the domains forming ... |
2,325,783 | MECHANISMS IN ENDOCRINOLOGY: Cushing's syndrome causes irreversible effects on the human brain: a systematic review of structural and functional magnetic resonance imaging studies. | Cushing's syndrome (CS) is characterized by excessive exposure to cortisol, and is associated with both metabolic and behavioral abnormalities. Symptoms improve substantially after biochemical cure, but may persist during long-term remission. The causes for persistent morbidity are probably multi-factorial, including a... |
2,325,784 | Interference with protease-activated receptor 1 does not reduce damage to subventricular zone cells of immature rodent brain following exposure to blood or blood plasma. | Prior work showed that whole blood, plasma, and serum injections are damaging to the neonatal rodent brain in a model of intracerebral/periventricular hemorrhage. Thrombin alone is also damaging. In adult animal models of hemorrhagic stroke, the protease-activated (thrombin) receptor PAR1 mediates some of the brain dam... |
2,325,785 | Progressive cortical thinning and subcortical atrophy in dementia with Lewy bodies and Alzheimer's disease. | Patterns of progressive cortical thinning in dementia with Lewy bodies (DLB) remain poorly understood. We examined spatiotemporal patterns of cortical thinning and subcortical atrophy over 12 months in DLB (n = 13), compared with Alzheimer's disease (AD) (n = 23) and healthy control subjects (HC) (n = 33). Rates of tem... |
2,325,786 | Chordoid glioma: Case report and review of the literature. | Chordoid glioma is a rare low-grade brain tumor originating from the anterior wall of the third ventricle.</AbstractText>A 13-year-old female with progressive intermittent holocranial headaches and a diagnosis of chordoid glioma underwent tumor resection in our neuro-oncology unit.</AbstractText>We review all 79 cases ... |
2,325,787 | Simulated ventriculostomy training with conventional neuronavigational equipment used clinically in the operating room: prospective validation study. | Simulation is gaining increasing interest as a method of delivering high-quality, time-effective, and safe training to neurosurgical residents. However, most current simulators are purpose-built for simulation, being relatively expensive and inaccessible to many residents. The purpose of this study was to provide the f... |
2,325,788 | Central fever in patients with spontaneous intracerebral hemorrhage: predicting factors and impact on outcome. | Central fever (CF) is defined as elevated temperature with no identifiable cause. We aimed to identify risk factors for developing CF among patients with spontaneous intracerebral hemorrhage (ICH) and to evaluate the impact of CF on outcome.</AbstractText>Patients included in our prospective stroke registry between 1/1... |
2,325,789 | The diffeomorphometry of regional shape change rates and its relevance to cognitive deterioration in mild cognitive impairment and Alzheimer's disease. | We proposed a diffeomorphometry-based statistical pipeline to study the regional shape change rates of the bilateral hippocampus, amygdala, and ventricle in mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with healthy controls (HC), using sequential magnetic resonance imaging (MRI) scans of 713 su... |
2,325,790 | Brain alterations within the first 100 days of HIV infection. | Brain involvement is a serious complication of HIV infection. The earliest changes in the brain, which represents an anatomic site for viral persistence, are largely unknown.</AbstractText>This investigation used quantitative Magnetic Resonance methodologies, including high resolution and diffusion tensor (DTI) imaging... |
2,325,791 | The anatomical location of the corticobulbar tract at the corona radiata in the human brain: diffusion tensor tractography study. | Many studies have reported on the anatomical location of the corticobulbar tract (CBT). However, no study has reported on the anatomical location of the corona radiata (CR). Using diffusion tensor tractography, we investigated the anatomical location of the CBT at the CR in normal subjects. Forty healthy normal subject... |
2,325,792 | Involvement of the δ-opioid receptor in exercise-induced cardioprotection. | What is the central question of this study? Does the δ-opioid receptor trigger exercise-induced cardioprotection against ischaemia-reperfusion injury? What is the main finding and its importance? In exercised hearts, the δ-opioid receptor appears to trigger cardioprotection against ischaemia-reperfusion-ind... |
2,325,793 | The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity. | Our previous study conducted after intracerebroventricular DSP-4 injection showed an important stimulating role of a brain noradrenergic system in the neuroendocrine regulation of liver cytochrome P450 (CYP) expression. The aim of the present research was to study involvement of the dorsal noradrenergic pathway of the ... |
2,325,794 | Allopregnanolone enhances the neurogenesis of midbrain dopaminergic neurons in APPswe/PSEN1 mice. | An earlier study has demonstrated that exogenous allopregnanolone (APα) can reverse the reduction of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra pars compacta (SNpc) of 3-month-old male triple transgenic Alzheimer's disease mouse (3xTgAD). This paper is focused on further clarifying the ori... |
2,325,795 | Defects in subventricular zone pigmented epithelium-derived factor niche signaling in the senescence-accelerated mouse prone-8. | We studied potential changes in the subventricular zone (SVZ) stem cell niche of the senescence-accelerated mouse prone-8 (SAM-P8) aging model. Bromodeoxyuridine (BrdU) assays with longtime survival revealed a lower number of label-retaining stem cells in the SAM-P8 SVZ compared with the SAM-Resistant 1 (SAM-R1) contro... |
2,325,796 | Serum fetuin-A levels in subjects with and without choroid plexus calcification. | Choroid plexus is an intraventricular plexus of tissue which is responsible for secretion of cerebrospinal fluid. Calcification of choroid plexus is found to be associated with age and gender. One of novel and popular glycoprotein that involves in inhibition of mineralization is human fetuin-A. In our study, we investi... |
2,325,797 | Temperature dependence of postmortem MR quantification for soft tissue discrimination. | To investigate and correct the temperature dependence of postmortem MR quantification used for soft tissue characterization and differentiation in thoraco-abdominal organs.</AbstractText>Thirty-five postmortem short axis cardiac 3-T MR examinations were quantified using a quantification sequence. Liver, spleen, left ve... |
2,325,798 | Emergency department diagnosis of pulmonary hypertension in a patient with left atrial sarcoma. | Pulmonary hypertension is a disease with many etiologies and is responsible for 200,000 admissions and 25,000 hospitalizations in the United States each year. We report the case of a previously healthy 58-year-old woman who presented to the emergency department with a months-long history of worsening dyspnea on exertio... |
2,325,799 | Postshunt lateral ventricular volume, white matter integrity, and intellectual outcomes in spina bifida and hydrocephalus. | No previous reports exist that have evaluated the relationships of white matter (WM) integrity with the number of shunt revisions, ventricular volume after shunting, and cognition in medically stable children who have spina bifida and hydrocephalus (SBH). The authors hypothesized that enlarged ventricles and a greater ... |
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