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3.2 Responsibilities .................................................................................................................... 27 |
3.3 Meetings and Minutes .......................................................................................................... 27 |
3.4 Procedural Rules .................................................................................................................. 28 |
3.5 Decision-Making .................................................................................................................. 28 |
3.6 Limits on Decision-Making ................................................................................................. 29 |
3.7 Alliance Managers ............................................................................................................... 29 |
3.8 Discontinuation of Committees ............................................................................................ 29 |
3.9 Interactions Between a Committee and Internal Teams ....................................................... 30 |
3.10 Subcommittees ..................................................................................................................... 30 |
3.11 Expenses ............................................................................................................................... 30 |
3.12 Authority .............................................................................................................................. 30 |
ARTICLE 4 GRANT OF LICENSES ........................................................................................................ 30 |
4.1 Licenses to AbbVie .............................................................................................................. 30 |
4.2 Sublicensing Rights .............................................................................................................. 31 |
4.3 UPenn Rights ....................................................................................................................... 31 |
4.4 No Other Rights ................................................................................................................... 32 |
4.5 Confirmatory Patent License ................................................................................................ 32 |
4.6 In-License Agreements ........................................................................................................ 32 |
4.7 Rights in Bankruptcy............................................................................................................ 32 |
ARTICLE 5 POST-LICENSE OPTION EXERCISE ACTIVITIES .......................................................... 33 |
5.1 Anima Transition Obligation Upon License Option Exercise ............................................. 33 |
5.2 AbbVie Development and Commercialization .................................................................... 33 |
5.3 AbbVie Diligence Obligation .............................................................................................. 33 |
ARTICLE 6 GENERAL PROVISIONS RELATING TO ACTIVITIES .................................................. 34 |
6.1 Compliance .......................................................................................................................... 34 |
6.2 Regulatory Activities ........................................................................................................... 34 |
6.3 Performance by Affiliates and Sublicensees ........................................................................ 34 |
6.4 Subcontracting ..................................................................................................................... 34 |
6.5 Records and Audits .............................................................................................................. 35 |
ARTICLE 7 UPFRONT FEE; MILESTONES AND ROYALTIES; PAYMENTS .................................. 35 |
7.1 Upfront Fee .......................................................................................................................... 35 |
7.2 Additional Target Program Fee ............................................................................................ 35 |
7.3 Collaboration Target Substitution Fee ................................................................................. 35 |
7.4 License Option Period Extension Fee .................................................................................. 37 |
7.5 License Option Exercise Fee ................................................................................................ 38 |
7.6 Development and Regulatory Milestone Payments ............................................................. 38 |
7.7 Sales-Based Milestone Payments ......................................................................................... 40 |
7.8 Royalties ............................................................................................................................... 41 |
7.9 Royalty Term ....................................................................................................................... 42 |
7.10 Royalty and Milestone Adjustments .................................................................................... 42 |
7.11 Estimated Sales Levels ......................................................................................................... 43 |
7.12 Reports; Payment of Royalty ............................................................................................... 44 |
7.13 Financial Records ................................................................................................................. 44 |
7.14 Audit; Audit Dispute. ........................................................................................................... 44 |
7.15 Methods of Payments; Offsets ............................................................................................. 44 |
7.16 Taxes .................................................................................................................................... 45 |
7.17 Late Payments ...................................................................................................................... 46 |
7.18 Financial Obligations under In-License Agreements ........................................................... 46 |
ARTICLE 8 EXCLUSIVITY; CHANGE OF CONTROL ......................................................................... 46 |
8.1 Exclusivity ........................................................................................................................... 46 |
8.2 Change of Control of Anima ................................................................................................ 51 |
ARTICLE 9 INTELLECTUAL PROPERTY RIGHTS ............................................................................. 52 |
9.1 Ownership of Intellectual Property; Disclosure ................................................................... 52 |
9.2 AbbVie Patents .................................................................................................................... 52 |
9.3 Patent Prosecution and Maintenance ................................................................................... 53 |
9.4 Enforcement of Licensed IP ................................................................................................. 54 |
9.5 Infringement Claims by Third Parties .................................................................................. 54 |
9.6 Invalidity or Unenforceability Defenses or Actions ............................................................ 55 |
9.7 Third Party Licenses ............................................................................................................ 55 |
9.8 Product Trademarks ............................................................................................................. 56 |
9.9 Inventor's Remuneration ...................................................................................................... 56 |
9.10 International Nonproprietary Name ..................................................................................... 56 |
ARTICLE 10 CONFIDENTIALITY .......................................................................................................... 56 |
10.1 Product Information ............................................................................................................. 56 |
10.2 Confidentiality Obligations .................................................................................................. 57 |
10.3 Permitted Disclosures........................................................................................................... 58 |
10.4 Use of Name ......................................................................................................................... 59 |
10.5 Public Announcements......................................................................................................... 59 |
10.6 Publications .......................................................................................................................... 60 |
10.7 Return of Confidential Information ..................................................................................... 60 |
10.8 Survival ................................................................................................................................ 60 |
ARTICLE 11 REPRESENTATIONS AND WARRANTIES .................................................................... 60 |
11.1 Representations and Warranties of Both Parties .................................................................. 60 |
11.2 Representations, Warranties, and Covenants, as applicable, of Anima ............................... 61 |
11.3 Compliance with Applicable Law ........................................................................................ 66 |
11.4 Additional Covenants of Anima ........................................................................................... 66 |
11.5 Anti-Bribery and Anti-Corruption Compliance ................................................................... 66 |
11.6 Disclaimer ............................................................................................................................ 66 |
ARTICLE 12 INDEMNIFICATION; INSURANCE ................................................................................. 66 |
12.1 Indemnification by AbbVie .................................................................................................. 66 |
12.2 Indemnification by Anima ................................................................................................... 67 |
12.3 Procedure ............................................................................................................................. 68 |
12.4 Insurance .............................................................................................................................. 69 |
12.5 Limitation of Liability .......................................................................................................... 70 |
ARTICLE 13 TERM AND TERMINATION ............................................................................................ 70 |
13.1 Term ..................................................................................................................................... 70 |
13.2 Termination .......................................................................................................................... 71 |
13.3 Modification in Lieu of Termination ................................................................................... 72 |
13.4 Effects of Termination ......................................................................................................... 73 |
13.5 Effects of Termination in Terminated Territory .................................................................. 74 |
13.6 Accrued Rights; Surviving Provisions of the Agreement .................................................... 74 |
ARTICLE 14 MISCELLANEOUS ............................................................................................................ 75 |
14.1 Governing Law; Service ...................................................................................................... 75 |
14.2 Dispute Resolution ............................................................................................................... 75 |
14.3 Assignment ........................................................................................................................... 76 |
14.4 Force Majeure ...................................................................................................................... 77 |
14.5 Notices ................................................................................................................................. 77 |
14.6 Export Clause ....................................................................................................................... 78 |
14.7 Waiver; Non-Exclusion of Remedies ................................................................................... 78 |
14.8 Further Assurance ................................................................................................................ 78 |
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