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201
The cardiac cycle and the effects of neurohumors on myocardial contractility in the Asiatic eel Anguilla japonica, Timm. & Schle.
202
Characteristics of the noradrenergic innervation of the left atrium in the chick (Gallus gallus domesticus, L.).
203
Responsiveness of neurogenic hearts to octopamine.
204
Action of kainic acid on a glutamatergic synapse.
205
The effects of 5-hydroxytryptamine depletors and monoamine oxidase inhibitors on color changes of the fiddler crab, Uca pugilator: further evidence in support of the hypothesis that 5-hydroxytryptamine controls the release of red pigment-dispersing hormone.
206
Evidence of a gastrin-like substance in Rhinobatus productus.
207
5-hydroxytryptamine as a possible inhibitory neurotransmitter in the central nervous system of the leech, Haemopis sanguisuga.
208
Gastrin-like activity in an Indian python.
209
Kinetics of antibody--hapten reactions.
211
Effects of maleate on renal reabsorption of bicarbonate.
212
Bicarbonate inhibition of rat kidney aconitate hydratase isoenzymes.
210
Influence of pH and hypoxia on the success of defibrillation.
Clinical impressions about the problem of defibrillation during states of acid-base imbalance and hypoxia have been influenced by studies involving the effect of these derangements on the ventricular fibrillation threshold. Based on body weight, energy requirements for defibrillation in normal dogs were compared to req...
213
Metabolic studies in experimental renal dysfunction resulting from maleate administration.
214
Multiple endocrine adenomatosis-I and II.
215
A randomized double-blind study of timolol in patients with essential hypertension.
216
[Observation of permanent teeth adjacent to teeth damaged by trauma].
217
Idiopathic hypertrophic subaortic stenosis (hypertrophic obstructive cardiomyopathy) changing concepts-1975.
218
Pleural effusion associated with aortitis syndrome.
A patient with aortitis syndrome had a pleural effusion which subsided but reappeared with an exacerbation of aortitis symptoms while under antituberculosis treatment. The character of the fluid was that of an exudate, and the glucose concentration was normal. Clinical and laboratory features of the case suggest that t...
219
The metabolic fate of securinine.
220
[Transplantation and preservation of tissue-typized skin in burns].
At the Department of Plastic Surgery and Burns, Berufsgenossenschaftliche Unfalklinik Ludwigshafen-Oggersheim, a skinbank with typed skin has been established. The storage system consists of deep-freezing at -196 degrees C in liquid nitrogen. The transplantation of HL-A typed skin was evaluated from the clinical and hi...
222
[Ability of antilymphocyte sera to counteract the allogeneic inhibition of hematopoietic stem cells].
223
[Microenvironment of enzymes as 1 of the factors determining enzyme stability. Stabilization of soluble and immobilized horseradish peroxidase].
224
[3d regional meeting of the specialty field of supervisory nurses in Baden-Württemberg, Northern Group. June 25, 1975 in district hospital Heidenheim].
221
[Polyploidization and fusion of insect cells exposed to concanavalin A].
225
[Adverse effects of anti-epileptic drugs].
226
Charge properties of human pituitary and amniotic fluid prolactins.
The apparent isoelectric points (pI) in isoelectric focusing (IF) of human pituitary and amniotic fluid prolactin (hPRL), both non-iodinated and iodinated, were determined. Unresolved mixtures of pituitary hPRL isohormones E and F, and of at least five isohormones found in amniotic fluid, and plasma hPRL exhibit an ave...
227
Human and monkey prolactin and growth hormone: separation of polymorphic forms by isoelectric focusing.
The feasibility of using isoelectric focusing for the separation of primate pituitary growth hormone from prolactin and for the characterization of polymorphic forms of these hormones was explored. In a pH 3--10 gradient, extracts of both human and cynomolgus monkey pituitaries were each resolved into 4 growth hormone ...
228
The interaction of SO2 with proteins.
229
Ecological observation of the 137Cs-contamination in beef of animals from the southern-Bavarian area.
Certain climatic and edaphic conformations in the Bavarian sub-alpine mountains and in the Alps favor above all the development of a land utilization system and farm structures similar to those in the northern part of Scandinavia. In 1963/64, the years of the highest environmental contamination up to the present, we es...
230
Liver microsomal beta-glucuronidase and UDP-glucuronyltransferase.
Both UDP-glucuronyltransferase (GT) and beta-glucuronidase (betaG) were assayed in untreated liver microsomes. Optimum assay conditions were established with rat liver microsomes using p-nitrophenol (pNP) and its glucuronide (pNPGA) at the pH optima of GT (7.5) and betaG (4.5). The activities of the two enzymes were co...
231
Biochemical aspects of renal ammonia formation in metabolic acidosis.
In omnivorous creatures, the diet is acidogenic, especially as a result of the meat content, which gives rise to phosphoric and sulphuric acids, i.e., to metabolic acidosis. In the short term, metabolic acids are buffered by tissue proteins and bicarbonate (the 'alkali reserve'). In the longer term, acid must be excret...
232
Studies on the mechanism of the changes in serum and liver gamma-glutamyl transpeptidase activity. I. Experimental extrahepatic cholestasis in rabbits.
Serum, liver and renal gamma-glutamyl transpeptidase (GGT) activities were studied in four groups of rabbits: controls, rabbits with obstructive extrahepatic cholestasis, rabbits with obstructive anuria, and animals with combined obstructive extrahepatic cholestasis and obstructive anuria. Serum GGT was essentially inc...
233
Studies on the mechanism of the changes in serum and liver gamma-glutamyl transpeptidase activity. II. Experimental hexachlorobenzene porphyria in rabbits.
The mechanism responsible for the changes in serum and liver gamma-glutamyl transpeptidase (gamma-GT) activity was studied in a model of experimental hexachlorobenzene porphyria in rabbits. Porphyria followed the administration of hexachlorobenzene in doses of 280 mumol - kg-1 body weight, which were given daily throug...
234
Changes in erythrocyte 2,3 diphosphoglycerate in women following short term maximal exercise.
15 untrained women were subjected to a walking treadmill test to determine the influence of maximal exercise upon synthesis of erythrocyte 2,3 DPG. Although there was a 9.8% increase in the 2,3 DPG content following exercise, there was a concomitant 9.4% increase in the hemoglobin level; therefore, when 2,3 DPG is expr...
235
Hydroxylation of p-Coumaric acid by illuminated chloroplasts. The role of superoxide.
1. Chloroplasts isolated from leaves of spinach-beet (Beta vulgaris L. ssp. vulgaris) do not catalyse the hydroxylation of p-coumaric acid in the dark unless a reductant (such as ascorbate, NADH or NADPH) is added. Superoxide dismutase has no effect on this reaction. 2. Illuminated chloroplasts catalyse the hydroxylati...
236
Identification of chloride-binding sites in hemoglobin by nuclear-magnetic-resonance quadrupole-relaxation studies of hemoglobin digests.
35Cl minus-nuclear magnetic resonance (NMR) studies indicate that various digests of human hemoglobin with carboxypeptidase A and B, or a combination of the two, may be used for the identification of chloride binding sites. All the digestion products contain, like hemoglobin itself, at least two classes of binding site...
237
The internal-alkaline pH gradient, sensitive to uncoupler and ATPase inhibitor, in growing Clostridium pasteurianum.
1. The intracellular pH was measured in growing Clostridium pasteurianum with and acid-base equilibrium distribution method. [14C]Dimethyloxazolidinedione, [14]methylamine and [14C]acetic acid were used as "deltapH-indicators". During growth the extracellular pH decreased from 7.1 to 5.1; simultaneously the intracellul...
238
D-alanyl-D-alanine carboxypeptidase in the bacterial form and L-form of Proteus mirabilis.
Membranes of the bacterial form and the stable and unstable L-forms of Proteus mirabilis contain LD and DD-carboxypeptidase. The DD-carboxypeptidase is inhibited non-competitively by penicillin G. The enzyme of the bacterial form is highly penicillin-sensitive (Ki - 4 X 10(-9) M penicillin G). Inhibition is only partly...
239
Pigeon-liver NAD kinase. The structural and kinetic basis of regulation of NADPH.
NAD kinase was purified from pigeon liver by an improved procedure which included chromatography on phosphocellulose. The resultant preparation was homogeneous as judged by gel electrophoresis, but electrofocusing gave indications of heterogeneity. The enzyme appeared to be of molecular weight 270000, and to consist of...
240
Hydrogen ion changes and contractile behavior in the perfused rat heart.
The effect of acid-base alterations was analyzed using isolated rat hearts perfused at constant coronary perfusion pressure, and stimulated to contract at constant rat. The amount of shortening in the major axis and its derivative were measured to assess myocardial contractility. Both the 'respiratory' and 'metabolic' ...
241
Changes of EEG and pulmonary venous admixture during a protein load in patients with cirrhosis.
21 patients with cirrhosis of the liver and 24 control patients were studied before and after a protein load (120 g protein per day during one week). An EEG was recorded and a visual assessment of frequency pattern was performed. Venous admixture was estimated during hyperoxia. According to the EEG frequency pattern th...
242
Formation of fertilization acid by sea urchin eggs does not require specific cations.
243
Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations.
244
Cell transformation in isolated striated muscle of hydromedusae independent of DNA synthesis.
245
Induction of DNA synthesis by dichloroisoproterenol without initial rise of the cAMP level in the parotid gland of mouse.
246
Cell density-dependent stimulation of glutamine synthetase activity in cultured mouse teratoma cells.
247
Polyadenylation of nascent RNA during the embryogenesis of Ilyanassa obsoleta.
248
The effect of environmental pH upon acid hydrolase activities of cultured human diploid fibroblasts.
249
Enucleation of cells by density gradient centrifugation.
250
An evaluation of factors affecting the in vitro bioassay for erythropoietin.
Two main aspects of the in vitro mouse foetal liver cell assay for Erythroid Stimulating Factor (ESF) in human sera have been investigated. The haem extraction process has been shown to give specific and quantitative recovery of 59Fe labelled haem from haemoglobin thus confirming that the material assayed in human sera...
252
[Cryptorchism].
251
[Synthesis of N-substituted isoindolines].
Some derivatives of isoindoline were prepared in order to test their cardiovascular activity. Pharmacological tests showed that some of the compounds had moderate alpha-blocking and coronarodilatory activity whereas others had some local anesthetic activity.
253
[Elements of scientific work organization in ambulance feldshers' functions].
254
[Participation of feldshers and midwives in the secret and partisan activities during the great patriotic war].
255
[The organization of health education meetings, verbal reports, carnivals, reader's conferences].
256
[Problems concerning the training of feldshers in foreign countries].
257
[Mechanisms of the thermogenic action of noradrenaline during adaptation to cold].
In white rats both adapted and unadapted to cold, the RQ dynamics during cold exposure, noradrenaline and ganglion blocking agent administration, were studied. The adapted animals' RQ in thermoneutral conditions was shown to be a little higher than in the control rats; 0.5 mg/kg noradrenaline injections induced a clear...
258
Response to exogenous gonadotropins in the unresponsive ovary syndrome.
259
A comparative study of metal and plastic (Karman) cannulae for first trimester abortion by suction curettage.
260
Acute bacterial myositis following septic abortion. An unusual complication.
261
The binding of substrates and inhibitors to dihydrofolate reductase.
262
Euglena gracilis deoxyribonucleic acid polymerases: subcellular locations and variations during the cell cycle.
263
Monomer complexes of polyadenylic acid.
264
5-Carbamoylmethyluridine: a new minor nucleoside of transfer ribonucleic acid.
265
The protective effects of cephaloridine on rat kidney lysosomes in vitro.
266
[In vitro studies on human ovarian contractility (author's transl)].
267
[Studies on the energy for sperm motility (author's transl)].
268
Properties of urophysial proteins (urophysins) from the white sucker, Catostomus commersoni.
269
Glutamine synthetase in newborn mice homozygous for lethal albino alleles.
270
Chromosomal basis of the merozygosity in a partially deploid mutant of Pneumococcus.
A sulfonamide-resistant mutant of pneumococcus, sulr-c, displays a genetic instability, regularly segregating to wild type. DNA extracts of derivatives of the strain possess transforming activities for both the mutant and wild-type alleles, establishing that the strain is a partial diploid. The linkage of sulr-c to str...
271
Recombination as a requirement for segregation of a partially diploid mutant of Pneumococcus.
Conditions are described in which the pneumococcal mutant strain sulr-c, resistant to the drug sulfanilamide, gives rise to sensitive segregants resistant to nitrobenzoic acid at a frequency constant with time. This segregant frequency is markedly enhanced upon exposure of the cells to doses of ultraviolet light or mit...
272
[Extrabronchial effects of Bronchodilat in patients with asthma and chronic asthmatic bronchitis].
273
Involvement of the small intestine in systemic mast cell disease.
A patient is reported with mast cell infiltration of the small intestine in the absence of the skin involvement characteristic of mast cell disease. She also had subtotal villous atrophy responsive to a gluten-free diet. Criteria for diagnosing mast cell disease of the small intestine are proposed. The literature of sm...
274
Gastric pH and microflora of normal and diarrhoeic infants.
The microflora and pH of gastric contents were determined in breast-fed and in bottle-fed normal infants, in well nourished infants with acute diarrhoea and in infants with chronic diarrhoea and protein-calorie malnutrition. The last group of infants was reevaluated after recovery from diarrhoea and protein-calorie mal...
275
[Allogenic bone marrow transplantation in men].
276
[Bone marrow transplantation in patients with aplastic anemia].
277
[Analysis of clinical phenomena and changes in physico-chemical properties of the blood in mentally ill children].
278
[Biphasic (ulcer-forming and ulcer-preventing) effect of adrenaline in rats].
Adrenaline-induced gastric ulceration was studied in rats. Adrenaline in high doses caused gastric ulcer, which was completely blocked by pretreatment with alpha-blockers (phenoxybenzamine, dibenamine), but not by pretreatment with propranolol or atropine, nor by vagotomy, hypophysectomy or adrenalectomy. After success...
279
[Comparison of drug effects on the isolated rat colon and duodenum].
Adrenaline and isoproterenol elicited nearly maximal relaxation of the colon even in small doses, whereas increase in the doses caused greater relaxation in the duodenum. In the colon, these drugs prevented, to a great extent the contraction induced by acetylcholine (ACh) and serotonin but in the duodenum were totally ...
280
[Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum].
Enzymic properties of monoamine oxidase (MAO) in dog serum were studied and the following results were obtained. Some of enzymic properties of MAO in dog serum differed from that of mitochondrial MAO. When dog serum was fractionated by ammonium sulfate, proteins were concentrated in two fractions, such as 25 approximat...
281
[Combined use of bucolome and pyrazolone derivatives (1). Pharmacological activities and blood concentration].
A combination of two or more drugs may exert a drug-drug interaction, in which case the effect can be potentiated or antagonized. Such synergistic effects are well known in the case of pyrabital (barbital + aminopyrine) or irgapyrine (phenylbutazone + aminopyrine). Bucolome (BCP), a non-steroidal anti-inflammatory agen...
282
[Combined use of bucolome and pyrazolone derivatives (II). Complex formation due to interaction between bucolome and pyrazolones].
We have already reported that bucolome (BCP), a non-steroidal anti-inflammatory agent, potentiates significantly the analgesic and antipyretic effects of pyrazolones which are substituted by alkylamino group at 4-position of the pyrazolone ring. Physical and quantum chemistry were applied to the mechanism of this syner...
283
Fructose 1,6-bisphosphate aldolase activity of Rhizobium species.
FDP aldolase was found to be present in the cell-free extracts of Rhizobium leguminosarum, Rhizobium phaseoli, Rhizobium trifolii, Rhizobium meliloti, Rhizobium lupini, Rhizobium japonicum and Rhizobium species from Arachis hypogaea and Sesbania cannabina. The enzyme in 3 representative species has optimal activity at ...
284
Prevention of cell agglutination and competence in a genetically transformable strain of Pneumococcus by D-glucosamine and D-galactosamine.
In the presence of amino sugars D-glucosamine and D-galactosamine no spontaneous competence could be observed in the highly transformable R6bd strain of Pneumococcus or it was decreased by several orders of magnitude. The highest inhibition of competence was detected when the amino sugar at a concentration 5 mg/ml of t...
285
Effect of some aldoses on growth of Saccharomyces cerevisiae inhibited with molybdenum.
The inhibitory effect of molybdenum ions on growth of yeasts at pH 5.5 was found to be decreased by aldoses in the following order: D-talose greater than L-mannose greater than L-ribose greater than D-lyxose greater than L-galactose greater than L-arabinose greater than L-glucose greater than L-xylose. Increased concen...
286
Transport properties of membrane vesicles from Acholeplasma laidlawii. II. Kinetic characteristics and specificity of glucose transport system.
The glucose transport system of membrane vesicles isolated from Acholeplasma laidlawii is saturable, with a Km of 21.2 mum and V of 0.68 nmol min-1 (mg protein)-1. The process is pH-dependent and a break occurs in the Arrhenius plot at 15 degrees C. Exogenous substrates did not stimulate glucose transport probably due ...
287
Transport of 4-deoxy- and 6-deoxy-D-glucose in baker's yeast.
Tritium-labelled 4-deoxy-D-glucose (4-dglc) and 6-deoxy-D-glucose (6-dgcl) were prepared by catalytic hydrogenolysis of the corresponding deoxyiodo derivatives with gaseous tritium. The two sugars are transported into Saccharomyces cerevisiae by both the constitutive glucose and the inducible galactose carrier. Uranyl ...
288
Gluconic acid production by Penicillium puberulum.
Twenty-five Penicillium species isolated from Egyptian soil were examined for their ability to produce gluconic acid in surface culture. Of the eight species capable of producing gluconic acid, Penicillium puberulum gave the maximum yield (91% gluconic acid from glucose after 7 days of fermentation with 3% CaCO3). Pept...
289
A simple method of isolation and purification of cultures of wood-rotting fungi.
A simple method of isolation and purification of cultures of higher fungi, mainly wood-rotting fungi, without special requirements for the presence of nitrogencontaining nutrients is described. Parts of fruiting bodies, spores or infected wood is inoculated on Petri dishes with an agar medium of the following compositi...
290
The effect of CTAB, a cationic surfactant, on the absorption rate of [14C]tripalmitate from a test meal in the rat.
291
[Language of the other].
292
[Studies on low volume priming heart lung bypass (author's transl)].
This report concerns the feasibility of low volume priming extracorporeal circulation. Through this study, the bubble oxygenator with Zuhdi's heat exchange was used. Moderate hypothermia with surface cooling and hemodilution perfusion with 5 per cent D/W was evaluated in 32 mongrel dogs and 16 clinical open heart cases...
293
[Studies on extracorporeal circulation with large volume hemodilution using lactate ringer's solution and low molecular weight dextran: alterations of acid-base balance associated with intentional hemodilution (author's transl)].
Twenty mongrel dogs, weighing between 7.5 and 13.0 kg were used to investigate the percentage limits permissible for hemodilution using a double-helical reservoir heart-lung machine which has a 1,100 ml of priming volume. In both 40 and 50 per cent groups of intentional hemodilution by 30 minute extracorporeal circulat...
294
[Malignant rheumatoid arthritis].
295
Purification and characterization of phosphodiesterase from Crotalus venom.
A procedure for the purification of phosphodiesterase from Crotalus venom on DEAE-cellulose at alkaline pH is described. The enzyme gives a single band in polyacrylamide gels and is free of contaminating nucleolytic enzymes. The molecular weight is about 115000. Concentration in an Amicon ultrafiltrator gave a highly c...
296
Limited hydrolysis of tRNA by phosphodiesterase.
Digestion of tRNA by electrophoretically pure phosphodiesterase is limited to a short sequence of nucleotides at the 3'-terminus. On the average, four percent of all nucleotides can be released from tRNA. The optimum Mg2 concentration is 10mM and the optimum pH 9.2. The mode of action is a random attack by the enzyme o...
297
Ecdysone Oxidase, an enzyme from the blowfly Calliphora erythrocephala (Meigen).
In the blowfly, the formation of 3-dehydroecdysone from the insect molting hormone ecdysone is catalyzed by an enzyme which carries hydrogen from ecdysone and ecdysterone to oxygen. The enzyme is therefore called "ecdysone oxidase". Two methods are described for the detection of ecdysone oxidase activity, one using a r...
298
Using a hospital for desensitization of an outpatient's illness-related fears.
An outpatient with phobias related to enclosed places, hospitals, doctors, and cancer was treated by systematic desensitization; the facilities of a general hospital were used for part of the process. Steps in treatment included securing a complete psychiatric and social history, teaching the patient relaxation therapy...
299
Analog computer for base excess and HCO3-from pH and PCO2 electrodes.
300
Alcohol-related problems in a general hospital emergency room.