CUI1 stringlengths 8 8 | RELA stringlengths 3 54 | CUI2 stringlengths 8 8 | Name1 stringlengths 1 2.86k ⌀ | Name2 stringlengths 1 2.86k ⌀ | Def1 stringlengths 1 8.95k ⌀ | Def2 stringlengths 1 8.95k ⌀ |
|---|---|---|---|---|---|---|
C0000248 | mapped_to | C0001034 | 2-Acetylaminofluorene | Acetylaminofluorene | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the arylhydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide; used to study the carcinogenicity and mutagenicity of aromatic amines. |
C0000248 | measures | C1526679 | 2-Acetylaminofluorene | 2-Acetylaminofluorene:MCnc:Pt:Air:Qn | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | null |
C0000248 | inverse_isa | C0060517 | 2-Acetylaminofluorene | fluorene | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | null |
C0000248 | has_component | C1526679 | 2-Acetylaminofluorene | 2-Acetylaminofluorene:MCnc:Pt:Air:Qn | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | null |
C0000248 | inverse_isa | C1709342 | 2-Acetylaminofluorene | Organo-nitrogen Carcinogen | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | An organic carcinogen having a C-N bond incorporated in its structure. (NCI05) |
C0000248 | subset_includes_concept | C1880653 | 2-Acetylaminofluorene | FDA Established Names and Unique Ingredient Identifier Codes Terminology | A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines. | The terminology that includes terms pertaining to FDA/USP Substance Registration System (SRS), which is to support health information technology initiatives by generating unique ingredient identifiers (UNIIs) for substances in drugs, biologics, foods, and devices. |
C0000254 | inverse_isa | C0242910 | 2-Amino-5-phosphonovalerate | Excitatory Amino Acid Antagonists | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. |
C0000254 | mapped_to | C0045862 | 2-Amino-5-phosphonovalerate | 2-amino-7-phosphonoheptanoic acid | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000254 | mapped_to | C0081981 | 2-Amino-5-phosphonovalerate | CGP 39551 | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000254 | mapped_to | C0092488 | 2-Amino-5-phosphonovalerate | 2-amino-4-methyl-5-phosphono-3-pentenoic acid | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000254 | mapped_to | C0109208 | 2-Amino-5-phosphonovalerate | CGP 39653 | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000254 | mapped_to | C0255818 | 2-Amino-5-phosphonovalerate | CGP 43487 | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000254 | mapped_to | C0383631 | 2-Amino-5-phosphonovalerate | 2-amino-5-phosphono-3-pentenoic acid | The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. | null |
C0000257 | inverse_isa | C0242910 | 2-Aminoadipic Acid | Excitatory Amino Acid Antagonists | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. |
C0000257 | mapped_to | C0051243 | 2-Aminoadipic Acid | allysine | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0051323 | 2-Aminoadipic Acid | alpha-amino-gamma,delta-dihydroxyadipic acid | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0063113 | 2-Aminoadipic Acid | hydroxyallysine | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0289275 | 2-Aminoadipic Acid | N-(N-(4-(N-((3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl)-2-propynylamino)benzoyl)-gamma-glutamyl)-2-aminoadipic acid | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0386387 | 2-Aminoadipic Acid | allysine ethylene acetal | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0535441 | 2-Aminoadipic Acid | N-(1-((2,4-diamino-6-pteridinyl)methyl)-3,4-dihydro -2H-1,4-benzothiazine-7-carbonyl)-L-2-aminoadipic acid | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0601552 | 2-Aminoadipic Acid | allysine aldol | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0637920 | 2-Aminoadipic Acid | phthalyl-allysine-4-nitrobenzyl ester | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C0651430 | 2-Aminoadipic Acid | 2-amino-4,5-methanoadipate | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C1663618 | 2-Aminoadipic Acid | N(alpha)-benzyloxycarbonylaminoadipic acid delta-semialdehyde | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C2003820 | 2-Aminoadipic Acid | N(alpha)-benzyloxycarbonyl-aminoadipic acid | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | mapped_to | C2716034 | 2-Aminoadipic Acid | N-phosphopyridoxyl-alpha-aminoadipate | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | associated_with | C0523480 | 2-Aminoadipic Acid | alpha-Aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | inverse_isa | C1268874 | 2-Aminoadipic Acid | Amino acid derivative | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | Any derivatives of amino acids that containing amino (-NH2) and carboxyl (-COOH) groups. |
C0000257 | subset_includes_concept | C3899741 | 2-Aminoadipic Acid | CTRP Terminology | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | Terminology that is used to support NCI's Clinical Trials Reporting Program (CTRP), a database that captures the required reporting data for all NCI-sponsored clinical trials. |
C0000257 | subset_includes_concept | C4684827 | 2-Aminoadipic Acid | CTRP Biomarker Terminology | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | A set of terms that is comprised of the biomarkers referenced in NCI-sponsored clinical trials. |
C0000257 | inverse_isa | C0002520 | 2-Aminoadipic Acid | Amino Acids | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins. |
C0000257 | measures | C1254998 | 2-Aminoadipic Acid | Alpha-Aminoadipic Acid Test | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | measures | C1255008 | 2-Aminoadipic Acid | Urine Alpha-Aminodipic Test | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | measures | C1255009 | 2-Aminoadipic Acid | Intravascular Alpha-Aminodipic Test | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | measures | C1255010 | 2-Aminoadipic Acid | Plasma Alpha-Aminodipic Test | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | inverse_isa | C0311462 | 2-Aminoadipic Acid | Alpha amino acid | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_component | C0523480 | 2-Aminoadipic Acid | alpha-Aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_measured_component | C0523480 | 2-Aminoadipic Acid | alpha-Aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_component | C1266301 | 2-Aminoadipic Acid | 2-Aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_component | C1446089 | 2-Aminoadipic Acid | Plasma alpha-aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_component | C1446106 | 2-Aminoadipic Acid | Urine alpha-aminoadipate measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_component | C2082344 | 2-Aminoadipic Acid | plasma alpha-aminoadipic acid measurement | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | has_direct_substance | C2188514 | 2-Aminoadipic Acid | urine alpha-aminoadipic acid/creatinine ratio | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000257 | same_as | C1291200 | 2-Aminoadipic Acid | 2-Aminoadipate | A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). | null |
C0000263 | inverse_isa | C0003376 | 2-Aminopurine | Antimetabolites | A purine that is an isomer of ADENINE (6-aminopurine). | Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033) |
C0000263 | mapped_to | C0045587 | 2-Aminopurine | 2,6-diaminopurine | A purine that is an isomer of ADENINE (6-aminopurine). | One of a number of organic compounds that share a similar purine structure and possess antiviral and antitumor properties. 2,6-Diaminopurine nucleosides are versatile synthetic precursors for specific N-6 modifications of antiviral and antitumor agents. (NCI04) |
C0000263 | mapped_to | C0045860 | 2-Aminopurine | 2-amino-6-chloropurine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C0620582 | 2-Aminopurine | 2-amino-6-chloro-1-deazapurine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C0636457 | 2-Aminopurine | 2,6-diamino-8-purinol | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C0666489 | 2-Aminopurine | 9-(1,3-dioxolan-4-yl)-2-aminopurine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C0910389 | 2-Aminopurine | QYL 685 | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C0910390 | 2-Aminopurine | QYL 609 | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C1173132 | 2-Aminopurine | N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C1958733 | 2-Aminopurine | S6-methylthio-2-aminopurne | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C1958734 | 2-Aminopurine | 2-aminopurine-6-sulfonic acid | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C2605265 | 2-Aminopurine | N6-methoxy-2,6-diaminopurine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C3274575 | 2-Aminopurine | AZD7451 | A purine that is an isomer of ADENINE (6-aminopurine). | A tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity. AZD7451 binds to TRK, thereby preventing the neurotrophin-TRK interaction and subsequent TRK activation. This may eventually result in an inhibition of tumor cell proliferation in TRK-expressing tumor cells. TRK, a receptor tyrosine k... |
C0000263 | mapped_to | C3529414 | 2-Aminopurine | 9,9'-(1,2-ethanediylbis(oxymethylene))bis-2-amino-1,9-dihydro-6H-purin-6-one | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C3712224 | 2-Aminopurine | 1-(4-(6-(2-(isopropylsulfonyl)phenylamino)-9H-purin-2-ylamino)-3-ethoxyphenyl)piperidin-4-ol | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C3849044 | 2-Aminopurine | N2-(4-aminocyclohexyl)-9-cyclopentyl-N6-((6-(2-furyl)-3-pyridyl)methyl)purine-2,6-diamine | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C3849045 | 2-Aminopurine | 2-(((2-((4-aminocyclohexyl)amino)-9-cyclopentylpurin-6-yl)amino)methyl)-4-chlorophenol | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000263 | mapped_to | C4078687 | 2-Aminopurine | SKLB261 | A purine that is an isomer of ADENINE (6-aminopurine). | null |
C0000266 | has_ingredient | C0355759 | Parlodel | bromocriptine 5 MG Oral Capsule [Parlodel] | null | null |
C0000266 | has_ingredient | C0356595 | Parlodel | bromocriptine 2.5 MG Oral Tablet [Parlodel] | null | null |
C0000266 | has_tradename | C0006230 | Parlodel | bromocriptine | null | A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion. |
C0000266 | has_ingredient | C0355759 | Parlodel | bromocriptine 5 MG Oral Capsule [Parlodel] | null | null |
C0000266 | has_ingredient | C0356594 | Parlodel | bromocriptine 1 MG Oral Tablet [Parlodel] | null | null |
C0000266 | has_ingredient | C0356595 | Parlodel | bromocriptine 2.5 MG Oral Tablet [Parlodel] | null | null |
C0000266 | has_ingredient | C0356597 | Parlodel | bromocriptine 10 MG Oral Capsule [Parlodel] | null | null |
C0000266 | has_ingredient | C1240459 | Parlodel | bromocriptine Oral Capsule [Parlodel] | null | null |
C0000266 | has_ingredient | C1242530 | Parlodel | bromocriptine Oral Tablet [Parlodel] | null | null |
C0000266 | has_ingredient | C1596335 | Parlodel | bromocriptine 5 MG [Parlodel] | null | null |
C0000266 | has_ingredient | C1596502 | Parlodel | bromocriptine 1 MG [Parlodel] | null | null |
C0000266 | has_ingredient | C1596503 | Parlodel | bromocriptine 2.5 MG [Parlodel] | null | null |
C0000266 | has_ingredient | C1596504 | Parlodel | bromocriptine 10 MG [Parlodel] | null | null |
C0000266 | has_ingredient | C3236216 | Parlodel | Parlodel Oral Product | null | null |
C0000266 | has_ingredient | C3236217 | Parlodel | Parlodel Pill | null | null |
C0000266 | has_tradename | C0546852 | Parlodel | bromocriptine mesylate | null | The mesylate salt of bromocriptine, a semisynthetic ergot alkaloid with dopaminergic, antidyskinetic, and antiprolactinemic activities. Bromocriptine selectively binds to and activates postsynaptic dopamine D2 receptors in the corpus striatum of the central nervous system (CNS). Activation of these D2 receptors activat... |
C0000266 | has_tradename | C0546852 | Parlodel | bromocriptine mesylate | null | The mesylate salt of bromocriptine, a semisynthetic ergot alkaloid with dopaminergic, antidyskinetic, and antiprolactinemic activities. Bromocriptine selectively binds to and activates postsynaptic dopamine D2 receptors in the corpus striatum of the central nervous system (CNS). Activation of these D2 receptors activat... |
C0000268 | mapped_from | C0024334 | 2-bromolysergic acid diethylamide | Lysergic Acid Diethylamide | null | Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, ... |
C0000268 | mapping_qualifier_of | C0002776 | 2-bromolysergic acid diethylamide | analogs & derivatives | null | Used with drugs and chemicals for substances that share the same parent molecule or have similar electronic structure but differ by the addition or substitution of other atoms or molecules. It is used when the specific chemical heading is not available and no appropriate group heading exists. |
C0000275 | mapped_to | C0045163 | 2-Chloroadenosine | 2'-chloro-2'-deoxyadenosine | 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system. | null |
C0000275 | mapped_to | C0045990 | 2-Chloroadenosine | 2-chloro-3'-deoxyadenosine | 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system. | null |
C0000275 | mapped_to | C0097728 | 2-Chloroadenosine | 5'-sulfamoyl-2-chloroadenosine | 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system. | null |
C0000275 | mapped_to | C0169868 | 2-Chloroadenosine | 8-chloroadenosine | 2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system. | An antimetabolite and a chlorine derivative of the purine nucleoside adenosine, with potential antineoplastic activity. Upon administration, 8-chloro-adenosine is phosphorylated to form 8-chloro-adenosine triphosphate (8-chloro-ATP), which functions as a ribonucleoside analogue and competes with ATP during transcriptio... |
C0000287 | inverse_isa | C0021213 | 2-Hydroxy-5-nitrobenzyl Bromide | Indicators and Reagents | A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent. | Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagen... |
C0000289 | mapped_to | C0054265 | 2-Hydroxyphenethylamine | butopamine | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0065323 | 2-Hydroxyphenethylamine | LY 79771 | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0068148 | 2-Hydroxyphenethylamine | N-methylphenylethanolamine | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0096497 | 2-Hydroxyphenethylamine | 4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0130184 | 2-Hydroxyphenethylamine | N-(2-diethylaminoethyl)-N-(2-hydroxy-2-phenylethyl)-2,5-dichloroaniline | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0604954 | 2-Hydroxyphenethylamine | 2,3-dihydroxyphenylethanolamine | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0606030 | 2-Hydroxyphenethylamine | Normoten | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C0892691 | 2-Hydroxyphenethylamine | 4-(3-((2-hydroxy-2-phenethyl)amino)butyl)benzamide | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C2715524 | 2-Hydroxyphenethylamine | 3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C2929313 | 2-Hydroxyphenethylamine | norfenefrine / pholedrine | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C3492503 | 2-Hydroxyphenethylamine | 2-(2-(dimethylamino)ethyl)-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenol | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C3640215 | 2-Hydroxyphenethylamine | AT13148 | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | An orally available, small molecule inhibitor of AGC group kinases, with potential antineoplastic activity. AT13148 inhibits, in an ATP-competitive manner, the enzymatic activity of two AGC kinases, protein kinase B (PKB or AKT) and p70S6K which play key roles in the PI3K/PKB/mTOR signaling pathway. Blockade of this pa... |
C0000289 | mapped_to | C3712962 | 2-Hydroxyphenethylamine | cimbuterol | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
C0000289 | mapped_to | C3712963 | 2-Hydroxyphenethylamine | mapenterol | Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. | null |
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