query stringlengths 1 6.15k | document stringlengths 1 333k | dataset stringclasses 28 values |
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Cobalamin C is a rare inborn disorder of metabolism that results in multisystemic abnormalities, including progressive visual deficits. Although the cellular pathophysiology of cblC is a field of active study, little attention has been dedicated to documenting the cognitive consequences of the defect. The neuropsychological assessment of nine individuals aged between 23 months and 24 years was conducted to establish cognitive profiles. Results reveal a marked heterogeneity, with intellectual functioning ranging from extremely low to average, and cognitive difficulties (e.g., attention) evidenced even in those who are not intellectually disabled. Central nervous system abnormalities and multisystem disease are likely to be major contributing factors to the observed cognitive impairments, with the presence of visual deficits constituting an additional impediment to normal cognitive development. This study underscores the importance of conducting in-depth neuropsychological assessments in individuals with cblC, the results of which may be particularly helpful for clinical management, guidance toward rehabilitation services, and educational/vocational planning. | Intracellular cobalamin metabolism (ICM) defects can be present as autosomal recessive or X-linked disorders. Parenteral hydroxocobalamin (P-OHCbl) is the mainstay of therapy, but the optimal dose has not been determined. Despite early treatment, long-term complications may develop. We have analyzed the biochemical and clinical responses in five patients with early onset of different types of ICM defects (cblC: patients 1-3; cblA: patient 4; cblX: patient 5) following daily P-OHCbl dose intensification (DI). In patient 4, P-OHCbl was started at age 10 years and in patient 5 at age 5 years. OHCbl was formulated at either, 5, 25, or 50 mg/mL. P-OHCbl was intravenously or subcutaneously (SQ) delivered, subsequently by placement of a SQ injection port except in patient 4. In all patients, homocysteine and methylmalonic acid levels, demonstrated an excellent response to various P-OHCbl doses. After age 36 months, patients 1-3 had a close to normal neurological examination with lower range developmental quotient. In patient 3, moderate visual impairment was present. Patient 4, at age 10 years, had normal renal, visual and cognitive function. In cblX patient 5, epilepsy was better controlled. In conclusion, P-OHCbl-DI caused an excellent control of metabolites in all patients. In the three cblC patients, comparison with patients, usually harboring identical genotype and similar metabolic profile, was suggestive of a positive effect, in favor of clinical efficacy. With P-OHCbl-DI, CblA patient has been placed into a lower risk to develop renal and optic impairment. In cblX patient, lower P-OHCbl doses were administrated to improve tolerability. | s2orc_abstract_citation |
Is it illegal for a minor to have sex in the state of california? | Is it illegal to have sex with an emancipated minor in california? | wikianswers |
What is the theme song to charmed called? | Who sings the theme song from charmed? | wikianswers |
Anxiety sufferers! scary thoughts...am i alone? | Been diagnosed with mild anxiety. My anxiety stems from worrying that im a bad person and i might want to do horrible things even though i dont(want to do them) and never have.my psychiatrist told me its just a symptom but i feel like im alone in this. Has this happenend to any other anxiety sufferers? | yahoo_title_question |
Consequent effect of soil contamination with heavy metals on heavy metal concentrations in broad bean (Vicia faba L., ssp. maior) | Consequent effect of soil contamination with heavy metals on Broad Bean seed quality (Vicia faba L, ssp. major) | s2orc_citation_titles |
What is the half way point between New York and Georgia? | What is the half way point between savannah georgia nd new york city by car? | wikianswers |
Good thriller in Tom Clancy style with a good eye ... | Good thriller in Tom Clancy style with a good eye for the (realistic) details. The ending might be a bit far fetched (certainly given today's settings) but is inventive. Worth taking onto the plane for that 10hour flight! | amazon_reviews |
What is Geogre Bush's annual Presidential salary? | George Bush's salary per year? | wikianswers |
Is madam cj walker born by sarah breedlove on december 23 1867? | When was Madame CJ Walker born? | wikianswers |
Disable GUI event loop integration.
If an application was registered, this sets its ``_in_event_loop``
attribute to False. It then calls :meth:`clear_inputhook`. | def disable_gui(self):
gui = self._current_gui
if gui in self.apps:
self.apps[gui]._in_event_loop = False
return self.clear_inputhook() | codesearch |
Cause of large income gap between Chinese resident and countermeasures | The analysis of opportunity inequality, income-gap and public policy | s2orc_citation_titles |
Synthetic FLIR Signatures for Training and Testing Target Identification Classifiers | Synthetic forward-looking infrared signatures for training and testing target identification classifiers | s2orc_citation_titles |
what do insects use to prepare to overwinter | Hibernaculum (zoology) shut down; long exposure may lead to death. Insects survive colder winters through the process of overwintering, which occurs at all stages of development and may include migration or hibernation for different insects, the latter of which must be done in hibernacula. Insects that do not migrate must halt their growth to avoid freezing to death, in a process called diapause. Insects prepare to overwinter through a variety of mechanisms, such as using anti-freeze proteins or cryoprotectants in freeze-avoidant insects, like Soybean aphids. Cryoprotectants are toxic, with high concentrations only tolerated at low temperatures. Thus, hibernacula are used to avoid | paq |
Having sex during third trimester of pregnancy? | Is it safe to have sex during pregnancy third trimester? | wikianswers |
O2 Academy Islington | The O2 Academy Islington, formerly known as the Carling Academy Islington, is an indoor music venue situated in the N1 Shopping Centre accessible via Upper Street and Liverpool Road, in the London Borough of Islington. It is run by the Academy Music Group. The main venue has a capacity of 800, and the adjacent O2 Academy 2 holds 250.
History
The venue was purpose-built and opened in September 2002. The original occupant was the short-lived Marquee N1, a music and dining venue backed by Dave Stewart of Eurythmics and club promoter Mark Fuller.
The venue re-opened in its current form in September 2003 and is the smallest of the four London venues within the O2 Academy Group.
Performers
American punks Alkaline Trio performed on the venue's opening night. Other notable performers who have played at the O2 Academy Islington include MELYS, Iron Butterfly, Molly Hatchet, Tesla, Dan Reed Network, Night Ranger, Isolated Islands, Bladee, Blackfoot, Queensrÿche, KISS, Kamelot, KSI, Spock's Beard, Stratovarius, Terrorvision, Stryper, Winger, Paul Gilbert, Richie Kotzen, Steve Lukather, Steve Harley and Cockney Rebel The Winery Dogs, Diamond Head, Premiata Forneria Marconi, Edguy, Symphony X, Threshold, Big Country, Magnum, Riverside, Satyricon, FM, Train, The Damned, MaNga, Melanie C, Zebrahead, Funeral for a Friend, Hugh Cornwell, Tarja Turunen, Jello Biafra, Gackt, Girugamesh, Hikaru Utada, The Jon Spencer Blues Explosion, Coheed and Cambria, VAMPS, August Burns Red, Max Milner, The Script, The Rasmus, Tyler, The Creator, Fall Out Boy, Silversun Pickups, Yeah Yeah Yeahs, Paramore, East 17, Morbid Angel, Dimmu Borgir, Sarah Harding, Tokio Hotel, R5, My Chemical Romance (who recorded the music video for their single Planetary (Go!) there), The Rutles, Stephen Dale Petit, Matt Stevens, Mick Taylor, JoJo, James Maslow, Achilles Heel, Toploader and Roger Chapman, Road Trip.
Events
The Academy also hosts the weekly club nights Club de Fromage and Burn Down The Disco every Saturday.
References
External links
O2 Academy Islington
O2 Academy Islington Review
Music venues in London
Buildings and structures in Islington
Tourist attractions in the London Borough of Islington
Academy Islington
Wrestling venues | wikipedia |
Lupus erythematosus keratoconjunctivitis. | Systemic Lupus Erythematosus Presenting as Corneal Perforation | s2orc_citation_titles |
I used these coolers for my son's graduation party and they worked awesome. Kept everything nice and cold | Product arrived on time. I used these coolers for my son's graduation party and they worked awesome. Kept everything nice and cold. Will definitely purchase again. | amazon_reviews |
Eucalypt Improvement : Efforts and Achievements in India | Provenance Trial of Eucalyptus tereticornis in Punjab | s2orc_citation_titles |
What's the deal with "Han shot first"? I understand a scene was changed by George Lucas, but why did he do it and why did it piss everybody off so much? | In the original scene a bounty hunter had his gun on Han at a table an Han shoots him underneath the table. It was altered twice since. One where the bounty hunter shoots first an misses and then Han shoots him and another where the bounty hunter shoots up, for some reason, and Han shoots him. Part of Han's character, especially at the beginning, was that he was a criminal of dubious morality. Of course he'd shoot a guy that had a gun on him. The fact that George Lucas, later in life, alters that important scene is just infuriating. It affects just what kind of person Han was. Also, the only copies of Star Wars that are the original war are VHS. | eli5 |
Where does little Richard live? | Where the f does little richard live? | wikianswers |
[WTS] Graphite AGS-101 + Dandelion GBC! | **This has been purchased! Thank you to everyone who was interested, hopefully in the future I can do business with the rest of you :)**
*I'm posting in this sub as /r/GameboyMarketplace seems to be restricted to custom/modified Gameboys. If I'm wrong about this however, please let me know. I've done my best to provide detailed photos on these Gameboys. If you feel I've missed something or you want clarification, don't hesitate to ask questions or request additional photos!*
***
I'm looking to sell two extra Gameboys I have to fund some recent projects I've planned out. I'm not looking to make any profit here, just a modest price to break even and get these Gameboys in the hands of people who can put them to better use.
The two that I'm looking to get rid of are a Graphite AGS-101 and a Dandelion GBC respectively. I've tried to capture every angle of the Gameboys (both straight on and angled to direct light) to show the condition on these consoles. Overall, they're both in very good condition and play perfectly.
Click here for the album!
I'm looking for $40 + S/H for the AGS-101, and $10 + S/H for the GBC. If anyone is interest in buying both, I'm doing a deal for $45! I'll also be throwing in a GBASP Charger (OEM) and GBC Battery Pack w/ Charger (Aftermarket) with each respective purchase. | reddit_title_body |
RYR1-related rhabdomyolysis: A common but probably underdiagnosed manifestation of skeletal muscle ryanodine receptor dysfunction | Exercise-Induced Rhabdomyolysis and Stress-Induced Malignant Hyperthermia Events, Association with Malignant Hyperthermia Susceptibility, and RYR1 Gene Sequence Variations | s2orc_citation_titles |
are butterfly knives illegal in pennsylvania? | It is legal to carry assisted-open knives, pocket knives, buck/bowie/hunting knives, butterfly/balisong knives, daggers and razors. Any knife thats blade is not exposed "in an automatic way by switch, push-button, [or] spring mechanism" is allowed in Pennsylvania, Reed said. | gooaq |
Looking for a name for my crew | Hey, I have been thinking of starting a crew, but i haven't thought of a name. I want it to be original, and not on of those names like West side deamons, or LA gangsters. I would like it to be an open crew, where people can join, and submit ideas. I would like it to be Mythologic in some way, or royal. Thanks for reading. | reddit_title_body |
What methods have the tryed to you to fix the problem in the gulf of mexico? | What are they doing to fix the gulf of mexico? | wikianswers |
A NEW SPECIES OF TROPIDURUS (SAURIA, IGUANIDAE) FROM THE ARID CHACOAN AND WESTERN REGIONS OF ARGENTINA | A review of the lizards of the iguanid genus Tropidurus in Peru | s2orc_citation_titles |
when did nickelodeon sunday come out | released to VHS and DVD in the U.S. by MGM Home Entertainment under the "DIC Movie Toons" label. In 2008, Gaiam re-released the films on DVD. Nickelodeon Sunday Movie Toons Nickelodeon Sunday Movie Toons was a series of animated made-for-TV movies, which lasted for just one season (2002) on Nickelodeon. It started on October 6, 2002 and ended on December 29, 2002. Produced by DIC Entertainment, the made-for-TV films are either based on various DIC productions such as "Inspector Gadget", "", and "Dennis the Menace", or are loose adaptations of stories from classic literature such as "Treasure Island" and "20,000 | paq |
Why investigate 9/11 ? | Why Investigate 9/11 ?\nhttp://www.911truth.org/article.php?story=20060817094039227\n \nthen watch all the scientifically researched documentary movies below:\n \n9/11 Mysteries (discusses melting temperatures of iron & steel)\n http://video.google.com/videoplay?docid=-6708190071483512003\n \nAlex Jones' Terror Storm (shows many examples of government terrarism)\n http://video.google.com/videoplay?docid=-7048572757566726569\n \nLoose Change ver 2 (shows videos of the controlled demolition squibs)\nhttp://www.seeloosechange.com\n \nImprobable collapse (discusses thermate found on WTC steel)\nhttp://video.google.com/videoplay?docid=4026073566596731782\n \nGood videos\nhttp://www.belowgroundsurface.org\nhttp://www.truth911.net\nhttp://www.plaguepuppy.net/public_html/collapse%20update/\nhttp://www.whatreallyhappened.com/wtc2_cutter.html\n\nScientific research\n http://www.scholarsfor911truth.org/WhyIndeedDidtheWorldTradeCenterBuildingsCompletelyCollapse.pdf\n\n(need Adobe PDF Reader)\n\nhttp://st911.org | yahoo_title_question |
Does not protect your phone. Cute, but pointless | This case is so cute, but won't keep your phone from breaking. I have the s7 and every time my phone hits the ground it pops off. It does not protect the front corners of your phone. I had the case on and was walking down the road and it fell out of my pocket and now the corner of my screen is cracked... new s7.. so pissed. Ordered a different case now, so this was a waste of money. | amazon_reviews |
@param $method
@param $item
@param null $module
@return bool|mixed | protected function getCachedResponse($method, $item, $module = null)
{
$method = 'can'.title_case($method);
if (!$module) {
$module = app('scaffold.module');
}
$key = $method.'_'.class_basename($item).'_'.md5(json_encode($item)).'_'.class_basename($module);
if ('testing' === app()->environment() || !array_key_exists($key, static::$responses)) {
$response = true;
$payload = [auth('admin')->user(), $item];
// Check for custom action method.
if (method_exists($this, $method)) {
$response = call_user_func_array([$this, $method], $payload);
}
// Check for CRUD authorizations in Scaffolding Resource.
elseif ($this->module->hasMethod($method)) {
$response = call_user_func_array([$this->module, $method], $payload);
}
// Check for CRUD authorizations from GuardManager service.
elseif (($guard = $this->module->guard()) && method_exists($guard, $method)) {
$response = call_user_func_array([$guard, $method], $payload);
}
static::$responses[$key] = $response;
}
return static::$responses[$key];
} | codesearch |
where are the doriot climatic chambers located in the army | Doriot Climatic Chambers The Doriot Climatic Chambers (DCCs) are a pair of very large, highly specialized wind tunnels/environmental chambers located at the U.S. Army’s Soldier Systems Center (SSC) in Natick, Massachusetts. Built in 1952, the Chambers are a unique facility, capable of simulating an extreme range of global weather conditions for the testing of both the physical properties of military equipment and the physiology and adaptations of human subjects. A variety of tenants utilize the DCCs, which are operated by the U.S. Army Research, Development, and Engineering Command (RDECOM). The DCCs were constructed from 1952 to 1954 at the time | paq |
Programming The Universe: Stellarium Scripting As An Inquiry Tool In Introductory College Astronomy | Applying Pre and Post Role-Plays Supported by Stellarium Virtual Observatory to Improve Students' Understanding on Learning Solar System | s2orc_citation_titles |
who invented the crystal oscillator in kdka | built the first quartz crystal oscillator in 1921. Other early innovators in quartz crystal oscillators include G. W. Pierce and Louis Essen. Quartz crystal oscillators were developed for high-stability frequency references during the 1920s and 1930s. Prior to crystals, radio stations controlled their frequency with tuned circuits, which could easily drift off frequency by 3–4 kHz. Since broadcast stations were assigned frequencies only 10 kHz apart, interference between adjacent stations due to frequency drift was a common problem. In 1925, Westinghouse installed a crystal oscillator in its flagship station KDKA, and by 1926, quartz crystals were used to control the | paq |
Parental assessment of disordered eating behaviors in their children with type 1 diabetes: A controlled study | Disordered Eating Behaviors Among Italian Adolescents with Type 1 Diabetes: Exploring Relationships with Parents’ Eating Disorder Symptoms, Externalizing and Internalizing Behaviors, and Body Image Problems | s2orc_citation_titles |
How big are lhasa poo's? | How big is a lhasa poo? | wikianswers |
Angry Sentinels and Businesslike Women: Identity and Marital Status in 1950s English Library Career | AbstractMuch energy has been exerted on the ‘image problem’ in librarianship, and negative representations of library spinsters. This paper outlines a different formulation of these issues by focusing on identity and constructions of marital status. It is argued that marital status was critical for women workers in this sector due to the widespread use of the marriage bar which curtailed women's employment on marriage. Yet we illustrate that women's identity cannot be assumed to be constructed within normative discourses of heterosexuality, and an alternative discursive approach to identity formation is outlined. The exemplars used are from library career novels published in the 1950s and 1960s. This paper was delivered at the Library History Group's ‘Libraries and Identity’ Conference, held at the Library Association's Under-One-Umbrella 5 meeting at UMIST, 1-3 July 1999· | s2orc_title_abstract |
Wht is the difference between law and principle in economics? | What is the basic difference between principle and law of management? | wikianswers |
What is the diognosis of swelling in the brain? | What is swelling of the brain? | wikianswers |
whats the reason for chloroquine resistance in plasmodium falciparum? | This is for your parasitology class, right.\nBasically, resistance to elimination by the plasmodium falciparum parasite is due to giving insufficient doses to the patient, thus helping the parasite build up a resistance to the chloroquine.\n\nThis is something to worry about with any parasite using any anti-parasitic. \n\nAny person administering anti-parasitics to a patient must calculate the dosage correctly to avoid resistance to treatment.\n\nCorrect weight/%/dose calculation will guarantee the parasite will be erradicated successfully.\n\nInterestingly, we have the same problem with cockroaches in our dwelling places, what? | yahoo_title_answer |
Microbial growth on the anesthesia machine. | Assessing a Novel Method to Reduce Anesthesia Machine Contamination: A Prospective, Observational Trial | s2orc_citation_titles |
Performance impact of parameter tuning on the CCSDS-123.0-B-2 low-complexity lossless and near-lossless multispectral and Hyperspectral Image Compression standard | Performance impact of parameter tuning on the CCSDS-123 lossless multi- and hyperspectral image compression standard | s2orc_citation_titles |
Clinical Encounters: The Social Justice Question in Intersectional Medicine | Broadening the Conversation About Intersectionality in Clinical Medicine | s2orc_citation_titles |
Name the scietist who invented light crystal display? | Who invented LCD light crystal display? | wikianswers |
Predicting conifer growth reduction from the analysis of neighborhood weed competition | Weeds in Eucalyptus globulus subsp. maidenii (F. Muell) establishment: effects of competition on sapling growth and survivorship | s2orc_citation_titles |
Laccase isozymes: production by an opportunistic pathogen, a Fusarium proliferatum isolate from wheat | Cell wall degrading enzymes and their impact on Fusarium proliferatum pathogenicity | s2orc_citation_titles |
Legit wayfarers but soooo stretched out | These are legit but beware of your pair has been worn!! I just received these in the mail and they almost fell off they were so loose. I took pictures next to my classic black wayfarers and you can see...they are SOOOO stretched out. Awful. Hard to commit to buying something higher value like this online again. Hard to verify quality even if it's garuanteed legit Rayban product. | amazon_reviews |
Does a woman discharge fluid in an orgasm? | Does a woman release fluid during orgasm? | wikianswers |
Kleene algebra is a great formalism for doing intraprocedural analysis and verification of programs, but it seems difficult to deal with interprocedural analysis where the power of context-free languages is often needed to represent both the program and the property. In the model checking framework, Alur and Madhusudan defined visibly pushdown automata, which accept a subclass of context-free languages called visibly pushdown languages, to do some interprocedural analyses of programs while remaining decidable. We present visibly pushdown Kleene algebra, an extension of Kleene algebra that axiomatises exactly the equational theory of visibly pushdown languages. The algebra is simply Kleene algebra along with a family of implicit least fixed point operators. Some interprocedural analyses of (mutually) recursive programs are possible in this formalism and it can deal with some non-regular properties. | Regular expressions (RE) are an algebraic formalism for expressing regular languages, widely used in string search and as a specification language in verification. In this paper, we introduce and investigate visibly rational expressions (VRE), an extension of RE for the class of visibly pushdown languages (VPL). We show that VRE capture precisely the class of VPL. Moreover, we identify an equally expressive fragment of VRE which admits a quadratic time compositional translation into the automata acceptors of VPL. We also prove that, for this fragment, universality, inclusion and language equivalence are EXPTIME-complete. Finally, we provide an extension of VRE for VPL over infinite words. | s2orc_abstract_citation |
can nonresident aliens claim child care expenses? | If you are a nonresident alien and receive effectively connected income, you may be able to claim some of the following credits: Foreign tax credit. Child and dependent care credit. | gooaq |
How extent can biofilm be? | Bacteria often attach to surfaces and form dense aggregations called biofilms or bacterial mats. These films can range from a few micrometers in thickness to up to half a meter in depth, and may contain multiple species of bacteria, protists and archaea. Bacteria living in biofilms display a complex arrangement of cells and extracellular components, forming secondary structures, such as microcolonies, through which there are networks of channels to enable better diffusion of nutrients. In natural environments, such as soil or the surfaces of plants, the majority of bacteria are bound to surfaces in biofilms. Biofilms are also important in medicine, as these structures are often present during chronic bacterial infections or in infections of implanted medical devices, and bacteria protected within biofilms are much harder to kill than individual isolated bacteria. | squad |
What is the real name of Prince Philip? | What is prince philip's real name? | wikianswers |
There's nothing to dislike about this product works very well for what I ... | There's nothing to dislike about this product works very well for what I needed them for. No flaws in the stainless steel or alum did the job. | amazon_reviews |
how many years are there at northwest florida state college | including OWC, to offer four-year degrees and be considered part of Florida's upper education under the newly formed Florida College Pilot Project making OWC one of the state colleges in Florida. Due to the change, school officials elected to once again change the name this time to Northwest Florida State College. NWFSC also has a charter high school called the Collegiate High School at Northwest Florida State College, which opened in 2000. The Collegiate High School at Northwest Florida State College (CHS) is a charter school in Niceville, Florida, established in 2000, that enables 10th, 11th and 12th grade students | paq |
What type of wood burns the fastest? | What kind of wood burns tyhe fastest? | wikianswers |
What happens when you reset your stats? | I have been wanting to reset my stats but I am scared I will my camos. When you reset your stats, what happens? What do you loose? If anyone could tell me I would greatly appreciate it. | reddit_title_body |
Surgical outcome measurement for a global patient population: Validation of the Surgical Apgar Score in eight countries | Utility of the Surgical Apgar Score in a District General Hospital | s2orc_citation_titles |
Which is the 1st hollywood film to be doubed in hindi? | Which was the first hollywood film to be dubbed in hindi? | wikianswers |
Where can you video chat free? | Where can yu video chat with friends and family for free? | wikianswers |
Dark current modeling with a moving depletion edge | Modeling Nonlinear Dark Current Behavior in CCDs | s2orc_citation_titles |
What is are antonyms for the word quarrel? | What is an antonym for quarrel worry argueagree or imagine? | wikianswers |
Thin-slots Machining of Compliant Needles for Vibration-assisted Medical Insertion | Vibration Study of Novel Compliant Needle used for Vibration-assisted Needle Insertion | s2orc_citation_titles |
A new type of phosphofructokinase deficiency hereditary nonspherocytic hemolytic anemia. | Inherited erythrocyte phosphofructokinase deficiency: Molecular mechanism | s2orc_citation_titles |
What was the purpose of Zheng Hes expensive voyage? | What was the main purpose of the Ming voyages of Zheng He? | wikianswers |
Cost comparison between endoscopic submucosal dissection and transanal endoscopic microsurgery for the treatment of rectal tumors | Endoscopic submucosal dissection (ESD) versus transanal endoscopic microsurgery (TEM) for treatment of rectal tumors: a comparative systematic review and meta-analysis | s2orc_citation_titles |
Which is the most american adults spend annualy? | What do american adults spend money on annually? | wikianswers |
The Orientation of Cytochrome c Oxidase in Coupled Phospholipid Membrane Vesicles—A Spin-Label Study | Cytochrome oxidase, an enzyme containing six different subunits, has been shown to span the inner mitochrondrial membrane. The arrangement of the subunits within the membrane is unknown. We have specifically labeled the 25 000 molecular weight subunit with a spin-label derivative of N-ethylmaleimide, 3-maleimido-2,2,5,5-tetramethyl-1-pyrrolidinyloxyl (NEM-SL(5)). NEM-SL(5)-labeled cytochrome oxidase can be incorporated into phospholipid membranes to form coupled vesicles of the Hinkle, Kim &Racker ((1972) J. Biol. Chem. 247, 1338–1339) type. The resonance spectrum of NEM-SL(5) is similar in both soluble and vesicular cytochrome oxidase. Since ascorbate has been shown to reduce only spin label that is exposed to the exterior surface of a closed vesicle, we have used ascorbate to determine the NEM-SL(5)-binding site in the coupled vesicles. NEM-SL(5)-labeled cytochrome oxidase vesicles are reduced by 10 mM ascorbate with of 1 min at 22 °C. The rate of reduction is relatively independent of temperature. We c... | s2orc_title_abstract |
Raman Scattering Study of Mixed Quaternary Ag x Ga x Ge1−x Se2 (0.167 ≤ x ≤ 0.333) Crystals | Experimental Raman scattering study of mixed AgxGaxGe1−xSe2 (0.167 ≤ x ≤ 0.333) single crystals is reported. The spectra transformation upon composition variation exhibits the two-mode type of behavior, with lines of the end-member compounds of the solid solution (AgGaSe2 and GeSe2) dominating in the spectra, whose relative intensities vary with composition. | s2orc_title_abstract |
Not the most effective fabric for a napkin but pretty. | Classy looking with matching tablecloth . Not the most effective fabric for a napkin but pretty . | amazon_reviews |
// HashLookup issues a FindFullHashes API call and returns the response. | func (a *netAPI) HashLookup(ctx context.Context, req *pb.FindFullHashesRequest) (*pb.FindFullHashesResponse, error) {
resp := new(pb.FindFullHashesResponse)
return resp, a.doRequest(ctx, findHashPath, req, resp)
} | codesearch |
Partial purification and some properties of tryptophan decarboxylase from Phalaris tuberosa | Tryptophan decarboxylase from Catharanthus roseus cell suspension cultures: purification, molecular and kinetic data of the homogenous protein | s2orc_citation_titles |
Fun, Semi-Competitive Deck: Immortal Pali | This is my first time sharing a deck, let me know if you like it.
Deck list here:
Immortal Pali is one of the more fun decks I've played, although it's not really very competitive on the ladder (you can get to around rank 15, but you'll have trouble getting past that).
The deck focuses on two things:
1. Getting lots of low-cost minions out on the board. The Flesheating Ghoul, Stormwind Champion, and Sea Giant all work well with a board full of cheap minions. Razorfen Hunter and Silver Hand Knight help you flood the board.
2. Having your hero equip weapons and take damage, and then healing it back later. The Spiteful Smith can make Light's Justice a great mana cost weapon. Molten Giant also combos well with a Guardian of Kings or Lay on Hands.
Obviously, the reason the deck is called "Immortal Pali" is the ridiculous amount of healing included for the hero. With 2x Truesilver Champion, 1x Darkscale Healer, 2x Guardian of Kings, and 1x Lay on Hands, you can heal your hero for 26 damage.
A few cards could easily be swapped out:
All of the 1 drops
Harvest Golem
Defender of Argus
Frost Elemental | reddit_title_body |
Pneumomediastinum in the Neonate | A Case of Congenital Bronchial Defect Resulting in Massive Posterior Pneumomediastinum: First Case Report | s2orc_citation_titles |
Roundtable: Excluding Black Jurors, Day Laborers | Tuesday's topics: Prosecutors exclude black jurors from trials; a controversial day-labor shelter for illegal workers; and a U.S. Department of Labor proposal to promote mandatory 401K plans. Guests: Walter Fields, CEO and publisher of the North Star Network; Nat Irvin, professor of future studies at Wake Forest University; and Rochelle Riley, columnist for the <EM>Detroit Free Press</EM>. | npr |
The autocorrelation matching method for distributed MIMO communications over unknown FIR channels | A new multiplex-access scheme based on the diversity of autocorrelation | s2orc_citation_titles |
Advances in the Production and Hatching of Resting Eggs of Cladoceran | The studies on resting eggs of cladoceran were reviewed in this paper.It was emphasized on the morphology of resting eggs,and the factors influencing resting eggs production,preservation and hatching of resting eggs.The resting eggs are usually roundness or oval,and there is a thick membrane outside them.The formation of resting eggs depends primarily on biological factors(genetic factors,population density,etc)and non-biological factors(temperature,food,illumination,etc).The factors affecting the hatching of resting eggs are the formation and time of preservation as well as illumination and temperature of hatching period. | s2orc_title_abstract |
Nutritional Composition of Freeze-Dried Bamboo Juice from Live Dendrocalamus giganteus Grown in Yunnan | Lipid Metabolism Effects of Freeze-dried Powder of Bamboo Juice on Liver Cell Line L02 with Steatosis | s2orc_citation_titles |
Will the presence of a nonvolatile solute decrease the freezing point of a solvent? | When the presence of a nonvolatile solute will do what to the freezing point of a solvent? | wikianswers |
What is the first thing you should do after retreiving a boat onto a trailor? | What is the first thing you should do after retrieving a boat onto a trailor? | wikianswers |
Automatic technique of distortion compensation in resistor ladder for high-speed and low-power ADC | A Resistor ladder is an important circuit block for parallel architecture analog-to-digital converters (ADCs). The output of ADC suffers from distortion due to kickback noise from comparators when the bias current of the resistor ladder is reduced to reduce its power dissipation. A technique of distortion compensation that cancels kickback noise by injecting compensation current to the resistor ladder has been known to overcome this problem. This technique, however, did not consider that kickback noise depends on the sampling frequency and variability of resistors. Therefore, we propose an automatic circuit for distortion compensation that detects the amount of kickback noise and properly adjusts the compensation current. The simulation results demonstrated that distortion could be reduced with the proposed technique even when the changes in sampling frequency and deviations in the resistor occurred. | s2orc_title_abstract |
how many seats does the boston symphony orchestra have in tanglewood | Tanglewood more than $30,000 was raised."" The following year, the Eliel Saarinen-designed, fan-shaped Shed (now known as the Koussevitzky Music Shed, or simply "the Shed") was constructed, with some 5,100 seats, giving the BSO a permanent open-air structure in which to perform. Broad lawns extend beyond the Shed, providing outdoor space for concert goers and sweeping views of Stockbridge Bowl and Monument Mountain in the distance. At the opening ceremony for the Shed on August 4, 1938, Gertrude Robinson Smith's dedication comments were recorded and can be heard today. The Boston Symphony Orchestra has performed in the Koussevitzky Music Shed every | paq |
The Colts agreed to terms Wednesday with Kerry Collins, making him the likely starter in case Peyton Manning hasn't completely recovered from off-season neck surgery when the season opens Sept. 11. | Colts agree to terms with Kerry Collins | sentence_compression |
When do baby rabbit open thier eyes? | When to baby rabbits open their eyes? | wikianswers |
360 VIDEO: Luxurious Las Vegas accommodations | Las Vegas is known for many things.
Bruno Mars, Lady Gaga, Celine Dion and Garth Brooks are regular performers on the Las Vegas Strip.
Celebrity chefs such as Robert Irvine, Emeril Lagasse and Guy Fieri have restaurants in Las Vegas.
Tourists flock to the Forum Shops at Caesars Palace and The Shops at Crystals to shop at high-end stores like Berlutti Paris, Cartier, Chanel, Christian Louboutin, Fendi, Jimmy Choo and Lanvin.
And while most people who visit Las Vegas each year -- more than 44 million in 2016 -- may splurge on a ticket to see a Cirque du Soleil production or eat in a fancy restaurant or even shop in a store they normally would not visit, the vast majority of tourists have no choice but to find the most inexpensive accommodations possible and just hope that they are clean.
However, it is a common fantasy to "live" like the rich and famous and many people are curious to see where celebrities like Beyonce, any of the Kardashians, or professional sports stars stay when they visit Las Vegas for fun or business.
ARIA RESORT AND CASINO
One of the many hotel-casinos on the famed Las Vegas Strip that offers a variety of suites is the Aria, which is part of the CityCenter complex.
The Sky Suites, which has been designated as a AAA Five Diamond retreat, at the Aria range in size from 1,050 square feet to 7,000 square feet.
VIEWS OF THE LAS VEGAS STRIP
Every suite at the Aria boasts floor-to-ceiling windows that offer incredible views of the Las Vegas Strip and a swimming pool that is only accessible by guests staying in the suites. Also, the suites at Aria are some of the most technologically advanced guest rooms in the country. Every guest room features a level of personalized automation currently only found in high-end custom homes.
TAKE THE VIRTUAL 360 TOUR OF A ONE-BEDROOM SUITE BELOW
SMART ROOMS
The suites recognize a guests' first time in the space and "greets" them as they enter: light fills the room, the curtains part to reveal the view, and the television turns on to display a list of automated controls for personalization.
The Aria is the largest hotel in the world to have earned LEED Gold certification.
Another unique feature in the Aria's suites is the popular washlet, which is an upscale toilet with a temperature-controlled heated seat, gentle aerated warm water, a warm air dryer, automatic air deodorizer, self-cleansing dual-action spray and soft close seat.
PERSONALIZED SERVICE
Luxury transportation to and from McCarran International Airport and a personal concierge is also made available to every guest who stays in Sky Suites.
The suites at the Aria range in price from $475 a night to $7,500 per night. The resort also has 16 restaurants, 10 bars and nightclubs and a 150,000-square-foot casino. Click here for more information. | ccnews |
When will eminem releas his next album? | When is eminem's next album coming out? | wikianswers |
Investing for a haircut. Thoughts? | Living in the South, hair can be the bane of your existence. I've been talking to my boyfriend for weeks about chopping my long locks off (I hate brushing). I looked into hair salons and they charge easily 50 bucks for a styling!
I'm terrified of going somewhere cheaper with less experience for such a change in my hair because it'll take forever to grow back.
My SO assured me he's fine with the pricing because he knows I always push for a friend/relative to trim it for me and we save money because I cut his hair, so technically, we saved over a hundred dollars over the years.
What do you think women of reddit? It's cringeworthy for a lot, but I'm trying to figure out if it's worth it paying for something new, but right. | reddit_title_body |
No invisible ink pages. | I bought this for my nephew, he is a fan of the show. He says the book is very neat, but he was disappointed by the absence of invisible ink pages. The blank pages in the book supposedly filled with invisible ink are just blank pages. | amazon_reviews |
Has ther e ever been a female president? | Was there ever a female president? | wikianswers |
Transforming growth factor-β (TGF-β) ligands activate Smad-mediated and noncanonical signaling pathways in a cell context–dependent manner. Localization of signaling receptors to distinct membrane domains is a potential source of signaling output diversity. The tumor suppressor/endocytic adaptor protein disabled-2 (Dab2) was proposed as a modulator of TGF-β signaling. However, the molecular mechanism(s) involved in the regulation of TGF-β signaling by Dab2 were not known. Here we investigate these issues by combining biophysical studies of the lateral mobility and endocytosis of the type I TGF-β receptor (TβRI) with TGF-β phosphoprotein signaling assays. Our findings demonstrate that Dab2 interacts with TβRI to restrict its lateral diffusion at the plasma membrane and enhance its clathrin-mediated endocytosis. Small interfering RNA–mediated knockdown of Dab2 or Dab2 overexpression shows that Dab2 negatively regulates TGF-β–induced c-Jun N-terminal kinase (JNK) activation, whereas activation of the Smad pathway is unaffected. Moreover, activation of JNK by TGF-β in the absence of Dab2 is disrupted by cholesterol depletion. These data support a model in which Dab2 regulates the domain localization of TβRI in the membrane, balancing TGF-β signaling via the Smad and JNK pathways. | Transforming growth factor β (TGFβ) family members signal via heterotetrameric complexes of type I (TβRI) and type II (TβRII) dual specificity kinase receptors. The availability of the receptors on the cell surface is controlled by several mechanisms. Newly synthesized TβRI and TβRII are delivered from the Golgi apparatus to the cell surface via separate routes. On the cell surface, TGFβ receptors are distributed between different microdomains of the plasma membrane and can be internalized via clathrin- and caveolae-mediated endocytic mechanisms. Although receptor endocytosis is not essential for TGFβ signaling, localization of the activated receptor complexes on the early endosomes promotes TGFβ-induced Smad activation. Caveolae-mediated endocytosis, which is widely regarded as a mechanism that facilitates the degradation of TGFβ receptors, has been shown to be required for TGFβ signaling via non-Smad pathways. The importance of proper control of TGFβ receptor intracellular trafficking is emphasized by clinical data, as mislocalization of receptors has been described in connection with several human diseases. Thus, control of intracellular trafficking of the TGFβ receptors together with the regulation of their expression, posttranslational modifications and down-regulation, ensure proper regulation of TGFβ signaling. | s2orc_abstract_citation |
Yotchiangrai | Yotchiangrai (also called Phraya Yot Chiang Ra and Yot Mueang) was the thirteenth monarch of the Mangrai Dynasty that ruled Lan Na in what is now northern Thailand. He was a son of Thao (Prince) Bunrueang, the only son of King Tilokaraj who had been executed by his grandfather on suspicion of disloyalty. He ruled from the death of his grandfather until he abdicated in favour of his son in 1495.
References
Rulers of Chiang Mai
15th-century monarchs in Asia
Year of birth unknown
Year of death unknown | wikipedia |
Negative Appendectomy and Imaging Accuracy in the Washington State Surgical Care and Outcomes Assessment Program | The Negative Appendectomy Rate: Who Benefits From Preoperative CT? | s2orc_citation_titles |
who wrote now i love the world i see no change of heart | moving on though what I used to be", the song was identified by author Thomas S. Hischak as a delicate, "moving ballad". Lyrically, the song is "about being at peace with oneself and how it’s expected as you grow up." It has also been described as "uplifting", featuring the lyrics "I never thought I’d leave behind / My childhood dreams / But I don’t mind / I’m where and who I want to be". The chorus ends "Now I love the world I see / No change of heart–a change in me". Vocally, "A Change in Me" is considered to | paq |
Differences in mourning dove productivity among three time periods at Gray Lodge Wildlife Area, California | Season, Weather, and Habitat Effects on Mourning Dove Nest Density | s2orc_citation_titles |
A simultaneous PET/MRI breast scanner based on the RatCAP | A Simultaneous PET/MRI scanner based on RatCAP in small animals | s2orc_citation_titles |
Serum adipokines levels in patients with systemic sclerosis: A meta-analysis. | Clinical associations of serum leptin and leptin/adiponectin ratio in systemic sclerosis | s2orc_citation_titles |
Bazaar.tf "Your profile is private!" Help | I can't get Bazaar.tf to work. When I log in it says "Your profile is private!" even though I changed all the settings to public. When I log out of Bazaar.tf and find my account I can see my backpack and everything. I hope someone could help me get pass this. Thanks | reddit_title_body |
Virginia State Route 607 | State Route 607 (SR 607) in the U.S. state of Virginia is a secondary route designation applied to multiple discontinuous road segments among the many counties. The list below describes the sections in each county that are designated SR 607.
List
References
External links
607 | wikipedia |
what was the name of the treaty signed by estonia and russia on 2 fe | Treaty of Tartu (Russian–Estonian) Tartu Peace Treaty (, literally "Tartu peace") or Treaty of Tartu is a peace treaty between Estonia and Soviet Russia signed on February 2, 1920 ending the Estonian War of Independence. The terms of the treaty stated that ""Russia unreservedly recognises"" the independence of the Republic of Estonia "de jure" and renounced in perpetuity all rights to the territory of Estonia. Ratifications of the treaty were exchanged in Moscow on March 30, 1920. It was registered in "League of Nations Treaty Series" on July 12, 1922. Estonia had been a province of Imperial Russia since 1710, | paq |
Phlegmasia cerulea dolens and gangrene associated with thrombophlebitis; case reports and review of the literature. | Phlegmasia Cerulea Dolens Treated with Fibrinolysin (Human) | s2orc_citation_titles |
2 Why do managers study motivation and behavior? | 3 Why do Managers study motivation and behavior? | wikianswers |
what is gtalk in gmail? | www.google.com/talk. Google Talk, also known as Google Chat (not to be confused with the current Google Chat), was an instant messaging service that provided both text and voice communication. The instant messaging service was variously referred to colloquially as Gchat, Gtalk, or Gmessage among its users. | gooaq |