PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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35,720,411 | ahr activ lead attenu murin autoimmun hepat singl cell rna seq analysi reveal uniqu immun cell phenotyp gene express chang liver aryl hydrocarbon receptor ahr ubiquit express ligand activ transcript factor initi identifi environment sensor receptor shown recent regul varieti immun function ahr ligand vari structur sour... | D019693;D000072317 | T121;T047;T109;T131 |
35,720,410 | acut phase trypanosoma cruzi infect liver lymphoid myeloid cell display ambigu phenotyp combin pro anti inflammatori marker multipl cell popul cellular biochem pathway autonom nervous system contribut maintain immunolog toler liver toler coher organ expos high level bacteri pathogen associ molecular pattern pamp molecu... | D014355;D014349 | T047;T204 |
35,720,408 | earli stage defens mechan cotton aphid aphi gossypii infect insect kill fungus beauveria bassiana jef aphi gossypii common known cotton aphid wide distribut pest agricultur crop act vector mani serious plant virus cotton aphid show high resist chemic insecticid due rapid rate genet divers result short life cycl season ... | D001042;D052982 | T004;T204 |
35,720,407 | love hate relationship tgf signal immun system develop tumorigenesi sinc tgf recogn essenti secret cytokin embryogenesi adult tissu homeostasi decad ago knowledg role tgf mammalian develop diseas particular cancer constant updat mount evid confirm tgf princip regul immun system depriv tgf signal complet abrog adapt imm... | D009369;D016212 | T191;T123;T116 |
35,720,406 | current strategi modul regulatori cell activ allerg inflamm past decad atop diseas includ allerg rhiniti asthma atop dermat food allergi increas strong worldwid reach industri countri diseas character domin type immun respons reduc number allergen specif regulatori treg cell convent allergen specif immunotherapi abl ti... | D065631;D050378 | T047;T025 |
35,720,405 | predict respons sever aplast anemia rabbit antithymocyt immunoglobulin base immunosuppress therapi combin eltrombopag addit eltrombopag e pag intens immunosuppress therapi ist contribut restor hematopoiesi patient sever aplast anemia saa use relat low dose east asian popul efficaci e pag predictor efficaci clear conduc... | D000741 | T047 |
35,720,403 | three oxid stress relat gene associ endometri immun cell consid potenti biomark predict unexplain recurr implant failur recurr implant failur rif repres new challeng field assist reproduct technolog art consid known effect immun cell regul embryo implant process well gene set variat analysi gsva result suggest associ r... | D010064;D004717 | T023;T040 |
35,720,402 | chimer antigen receptor car regulatori cell solid organ transplant solid organ transplant treatment choic various end stage diseas requir continu need immunosuppress prevent allograft reject come serious side effect includ increas infect rate develop malign thus clinic need promot transplant toler prevent organ reject ... | D016377;D000076962;D050378 | T116;T192;T061;T129;T025 |
35,720,401 | timelin kinet system airway immun mediat storm comprehens analysi diseas outcom critic ill covid patient present studi level serum airway solubl chemokin pro inflammatoryregulatori cytokin growth factor quantifi critic ill covid patient total n distinct time point upon intens care unit icu admiss augment level solubl m... | D000086382 | T047;T067 |
35,720,400 | increas seropreval improv antibodi respons follow third primari sar cov immunis updat cov ad studi patient primari secondari antibodi defici vulner covid demonstr diminish respons follow two dose sar cov vaccin schedul third primari vaccin deploy enhanc humor cellular immun | D000086382;D014765 | T121;T047;T067;T129 |
35,720,399 | dynam immun landscap vzv specif cell respons patient herp zoster postherpet neuralgia varicella zoster virus vzv induc herp zoster hz postherpet neuralgia phn immun cell play import role regul hz phn pathogenesi dynam immun profil molecular mechan remain unclear studi aim screen dynam immun signatur hz progress elucid ... | D006562;D051474 | T047 |
35,720,398 | granulocyt macrophag coloni stimul factor modul myeloid deriv suppressor cell treg activ decompens cirrhot patient sepsi decompens cirrhosi patient prone bacteri infect myeloid deriv suppressor cell mdscs expand sepsi patient disrupt immun cell function granulocyt macrophag coloni stimul factor gm csf therapi help rest... | D000072737;D018805 | T025;T046;T047 |
35,720,397 | relationship vitamin genet risk score autoantibodi among first degre relat proband rheumatoid arthriti system lupus erythematosus higher hydroxyvitamin oh level associ reduc risk autoimmun diseas influenc vitamin metabol gene estim genet determin vitamin level calcul genet risk score grs investig whether vitamin grs as... | D001172;D008180 | T047 |
35,720,396 | modul autoimmun autoinflammatori diseas gasdermin autoimmun diseas autoinflammatori diseas two type immun system disord pyroptosi high inflammatori cell death play import role diseas immun system gasdermin belong pore form protein gene famili main express immun cell gastrointestin tract skin gasdermin regard executor p... | D001327;D056660;D007154 | T047 |
35,720,395 | effect normotherm machin perfus immun profil donor liver normotherm machin perfus nmp allow viabil assess potenti resuscit donor liver prior transplant immunolog effect nmp liver allograft undetermin potenti implic allograft function reject outcom overal surviv studi defin chang immun profil human liver nmp | D016031 | T061 |
35,720,394 | high salt induc delay activ human neutrophil high salt nacl concentr found number tissu physiolog patholog condit analyz effect induc high salt function human neutrophil cultur neutrophil medium supplement high salt mm nacl short period min inhibit abil convent agonist induc product il activ respiratori burst contrast ... | D009504;D014409 | T025;T116;T129 |
35,720,393 | case report mucous membran pemphigoid igg iga anti laminin antibodi iga anti laminin antibodi mucous membran pemphigoid mmp anti laminin lm pemphigoid two subtyp subepiderm autoimmun bullous diseas character autoantibodi epiderm basement membran zone protein main show mucos skin lesion respect known autoantigen mmp inc... | D010390;D010391;D012872 | T047 |
35,720,392 | singl nucleotid polymorph snp snp snp interact surfact protein gene associ idiopath pulmonari fibrosi mexican studi group comparison hypersensit pneumon surfact protein sps import normal lung function innat immun lung gene identifi signific genet variabl chang quantiti qualiti sps due genet mutat natur genet variabl ma... | D000542;D054990;D011663 | T121;T047;T109;T123 |
35,720,391 | post transplant bilirubin nanoparticl amelior murin graft versus host diseas via reduct system local inflamm allogen stem cell transplant curat immunotherapi patient receiv myeloabl chemotherapi andor radiotherapi follow donor stem cell transplant graft versus host diseas gvhd major complic caus dysregul donor immun sy... | D006086;D053758 | T047;T073 |
35,720,390 | understand concept pre clinic autoimmun predict prevent system lupus erythematosus identifi risk factor develop strategi diseas develop grow evid preced diagnosi classif system lupus erythematosus sle patient undergo preclin phase diseas marker inflamm autoimmun alreadi present surpris even though sle manag improv year... | D001172;D001327;D008180 | T047 |
35,720,389 | egg deriv anti sar cov immunoglobulin igi broad variant activ intranas prophylaxi covid covid emerg use author approv vaccin achiev record time howev remain need develop addit safe effect easi produc inexpens prevent reduc risk acquir sar cov infect need due difficulti vaccin manufactur distribut vaccin hesit critic in... | D000086382;D000086402 | T047;T067;T005 |
35,720,388 | neoadjuv pembrolizumab chemotherapi resect esophag cancer open label singl arm studi pen ice singl arm studi efficaci safeti neoadjuv pembrolizumab plus chemotherapi evalu patient resect esophag squamous cell carcinoma escc | D000971;D004938;D000077277 | T191;T061 |
35,720,387 | untangl knot regulatori cell therapi solid organ transplant numer preclin studi provid solid evid support adopt transfer regulatori cell treg induc organ toler result current activ treg cell base clinic trial solid organ transplant worldwid earli phase phase iii trial although result trial optimist support safeti feasi... | D016377;D050378 | T061;T025 |
35,720,386 | b cell requir generat optim anti melanoma immun respons checkpoint blockad immunotherapi checkpoint blockad therapi known enhanc anti melanoma cd cell immun fraction patient treat therapi achiev durabl immun respons diseas control may cd cell need help immun cell generat effect long last anti tumor immun cd cell alon i... | D018414;D008546 | T191;T050;T025 |
35,720,385 | vaccin protect placenta breastfeed unmet topic covid pandem coronavirus diseas covid pandem turn pregnant women healthcar worldwid public health challeng although initi data demonstr pregnanc suscept period sever outcom acut sever acut respiratori syndrom relat coronavirus sar cov infect increas number report show preg... | D000086382;D011251;D014612 | T047;T116;T121;T129;T067 |
35,720,384 | autoantigen discoveri hair loss disord alopecia areata implic post translat modif alopecia areata aa chronic multifactori polygen heterogen disord affect grow hair follicl suscept individu result non scar revers hair loss high unpredict cours despit consider research effort natur precipit factor respons initi aa given ... | D000506 | T047 |
35,720,383 | diurnal differ intracellular replic within splenic macrophag correl outcom pneumococc infect circadian rhythm affect progress sever bacteri infect includ caus streptococcus pneumonia mechan respons phenomenon remain larg elus follow advanc understand role replic pneumonia within splenic macrophag sought investig whethe... | D011008;D018805 | T047;T046 |
35,720,382 | evalu host protein biomark elisa whole lyse peripher blood develop diagnost test activ tuberculosi tuberculosi tb remain signific global health crisi number one caus death infecti diseas health consequ high burden countri signific barrier tb control erad part caus difficulti diagnosi improv diagnosi requir organis like... | D000086382;D009169;D014376;D014397 | T007;T047;T067 |
35,720,381 | modif extracellular matrix product dha oxid switch macrophag adhes pattern promot retent macrophag chronic inflamm oxid polyunsatur fatti acid contribut differ aspect inflammatori respons due varieti product generat specif oxid dha produc end product carboxyethylpyrrol cep form coval adduct protein via amino group lysi... | D007797;D008264 | T025;T123;T116 |
35,720,380 | patholog inflamm malnutrit driven proinflammatori intestin microbiota larg intestin barrier dysfunct transloc bacteri lipopolysaccharid acut malnutrit wast implic half death children five increas risk infecti diseas studi human preclin model demonstr malnutrit link immatur intestin microbiota character increas preval e... | D005767;D000069196;D007410;D044342 | T007;T001;T047 |
35,720,379 | ccl releas ccr cd cell potenti contributor immunopatholog primari sjgren syndrom increas ccl express cd cell shown pivot regul immunopatholog primari sjgren syndrom pss pss like diseas increas ccl express ccr cd cell previous implic contributor immunopatholog pss role cd cell particular ccr cd cell potenti secret ccl p... | D018414;D018946;D054388;D012859 | T047;T116;T192;T129;T025 |
35,720,378 | neutrophil covid innoc bystand unusu viral infect immunolog phenotyp sever covid characteris deplet lymphocyt elev neutrophil count neutrophil lymphocyt ratio correl diseas sever neutrophil abund immun cell bloodstream compris differ subpopul pleiotrop action vital host immun uniqu neutrophil subpopul vari capac mount ... | D000086382;D065206 | T047;T026;T067 |
35,720,377 | vitamin supplement modul platelet mediat inflamm subject type diabet random doubl blind placebo control trial recent group identifi increas platelet mediat inflamm type diabet tdm patient well establish risk factor diabet complic particular develop cardiovascular diseas cvd furthermor vitamin report play import role mo... | D003924 | T047 |
35,720,376 | vaccin sar cov lung transplant recipi immunogen efficaci safeti lung transplant lutx recipi consid higher risk develop serious ill covid covid vaccin shown random clinic trial substanti reduc sever covid howev patient receiv immunosuppress exclud trial observ studi report proport solid organ transplant sot recipi abl m... | D000086382;D066027 | T101;T047;T067 |
35,720,375 | antimicrobi peptid mimic clinic use size matter search effici antimicrobi therapi allevi suffer caus infect resist bacteria urgent ever infect caus multi resist pathogen repres signific increas burden healthcar societi research investig new class bioactiv compound slow develop antimicrobi peptid innat immun system repr... | D000890;D023181 | T121;T123;T116;T129 |
35,720,374 | phase studi locoregion high dose autolog natur killer cell therapi hepat arteri infus chemotherapi patient local advanc hepatocellular carcinoma explor feasibl safeti natur killer nk cell therapi hcc perform prospect open label phase trial evalu synergist effect locoregion high dose autolog nk cell therapi combin hepat... | D006528;D064987;D008113 | T191;T061 |
35,720,373 | immun subtyp luad identifi novel tumor microenviron profil prognost therapeut implic six transcriptom immun subtyp iss c c report complex differ interplay tme cancer cell tcga cancer genom atlas pan cancer cohort studi specif explor consequ interplay determin prognosi respons therapi luad cohort clinic molecular inform... | D000077192;D008264;D059016 | T191;T025;T070 |
35,720,372 | halophil archaea halorhabdus rudnicka natrinema salacia activ human dendrit cell orient helper cell respons halophil archaea procaryot organ distinct bacteria known thrive hypersalin environ includ salt lake saltern brine salti food also identifi human microbiom biolog signific halophil human health rare examin interac... | D006216;D018793 | T116;T194;T129 |
35,720,371 | p peptid lead clearanc autoreact lymphocyt normal immun respons lupus prone mice system lupus erythematosus cell display multipl abnorm abnorm activ secret pro inflammatori cytokin help b cell generat pathogen autoantibodi provok accumul autoreact memori cell p synthet peptid evalu phase iii clinic trial lupus bind hsp... | D008180;D010446 | T047;T116 |
35,720,370 | singl cell rna atac sequenc reveal hemodialysi relat immun dysregul circul immun cell subpopul increas risk infect malign cardiovascular diseas mainten hemodialysi patient associ hemodialysi relat immun disturb although defect lymphocyt depend immun respons preactiv antigen present cell document hemodialysi patient eff... | D007963;D012313 | T025;T114 |
35,720,369 | identif isol type ii nkt cell subset human blood liver steatot liver prone reject often transplant owe shortag avail organ type ii nkt tnkt cell liver resid lymphocyt react lipid present cdd role tnkt cell reject fatti liver transplant unclear part lack tnkt cell marker low frequenc blood quantifi human tnkt cell blood... | D005234;D055611 | T047;T025 |
35,720,368 | cda biolog antibodi depend cell mediat cytotox improv antibodi depend cell mediat cytotox adcc potent cytotox mechan main mediat human natur killer nk cell adcc mediat clinic benefit sever wide use cytolyt monoclon antibodi mab increas efficaci would improv cancer immunotherapi cda receptor fc portion igg respons trigg... | D000074322;D017452 | T121;T192;T116;T129 |
35,720,367 | case report rubella virus induc cutan granuloma two pediatr patient dna doubl strand breakag repair disord outcom hematopoiet stem cell transplant report two patient dna repair disord artemi defici ataxia telangiectasia destruct skin granuloma presum trigger live attenu rubella vaccin patient show reduc nave cell rapid... | D001260;D049914;D018380;D007153 | T061;T047;T046 |
35,720,366 | antibodi respons covid booster vaccin healthcar worker evalu mean increas anti igg antibodi titer basal pre booster level titer assess day booster dose bntb | D000917;D000086382 | T038;T047;T067 |
35,720,365 | genom wide identif express profil indic expans famili proteas inhibitor via gene tandem duplic diverg razor clam sinonovacula constricta famili proteas inhibitor repres novel famili merop peptidas databas like uniqu molluscan host defens two famili member scsi scsi report razor clam sinonovacula constricta previous res... | D000890;D049872;D014736 | T121;T007;T204 |
35,720,364 | util drawback chimer antigen receptor cell car therapi lung cancer present treatment lung cancer includ surgic resect radiat chemotherapi target therapi immunotherapi despit advanc therapi prognosi lung cancer substanti improv recent year chimer antigen receptor car cell immunotherapi attract grow interest treatment va... | D008175;D000076962 | T191;T192;T116;T129 |
35,720,363 | immunoinformat approach toward introduct novel multi epitop vaccin clostridium difficil clostridium difficil cdifficil exclus anaerob spore form gram posit pathogen common caus nosocomi diarrhea becom increas preval communiti c difficil strict anaerob spore surviv month extern environ contribut persist diffus c diffici... | D016360 | T007 |
35,720,362 | quantifi reduct plasmodium falciparum infect mosquito sampl size calcul inform clinic trial transmiss reduc intervent malaria transmiss depend presenc matur plasmodium transmiss stage gametocyt may render blood feed anophel mosquito infecti transmiss block antimalari drug vaccin prevent transmiss reduc gametocyt densit... | D000852;D008288;D016778 | T047;T204 |
35,720,361 | adiponectin amelior gmh induc brain injuri regul microglia mm polar via adiporapplampkppar signal pathway neonat rat adiponectin apn fat deriv plasma hormon classic anti inflammatori agent multipl studi demonstr benefici role apn acut brain injuri effect apn germin matrix hemorrhag gmh unclear under molecular mechan re... | D001930;D017628 | T025;T037 |
35,720,360 | immun microenviron osteosarcoma compon therapeut strategi clinic applic osteosarcoma primari malign tumor tend threaten children adolesc year event free surviv rate improv signific past three decad bring grief econom burden patient societi date genet background oncogenesi mechan osteosarcoma remain unclear imped resear... | D001859;D055354;D012516 | T191;T026 |
35,720,359 | peripher organ injuri stroke stroke diseas high incid mortal disabl rate also main caus adult disabl develop countri stroke often caus small emboli inner wall blood vessel suppli brain lead arteri embol also caus cerebrovascular thrombot bleed except recombin tissu plasminogen activ rt pa thrombolyt drug use recan occl... | D002545;D020521 | T047;T046 |
35,720,358 | case report comorbid hyper igd syndrom hidraden suppurativa new syndrom form hs report two case hidraden suppurativa hs chronic suppur diseas pilosebac unit current model hs pathophysiolog describ condit product hyperkeratinis inflamm hair follicular unit environment factor smoke obes gender genet predisposit skin dysb... | D017497;D054078 | T047 |
35,720,357 | cd control gut immun shape cytokin profil intestin cell cd constitut express cell negat regul lymphocyt function howev full extent cd function immun remain unclear cd defici impact thymic select extra thymic regulatori cell generat yet cd knockout report caus immun patholog show cd key modul gut immun generat mice indu... | D018956 | T116;T129 |
35,720,356 | coevolv canon loop conform singl domain antibodi tale three pocket play music chair singl domain antibodi sdab promis class biotherapeut uniqu structur trait within paratop region distribut canon conform explor complementar determin region cdr loop differ extent convent two chain fv fragment monoclon antibodi mab studi... | D061905 | T116;T129 |
35,720,355 | fasciola hepatica fatti acid bind protein modul cell polar promot dendrit cell thrombospondin secret without affect metabol homeostasi obes mice parasit trematod fasciola hepatica evad host immun defens secret various immunomodulatori molecul fatti acid bind protein fh fabp among main excretedsecret protein shown displ... | D003924;D005210 | T047;T204 |
35,720,354 | adrenomedullin express associ sever poor prognosi interstiti lung diseas dermatomyos patient evalu adrenomedullin mrna level peripher blood mononuclear cell pbmcs patient dermatomyos dm well correl sever interstiti lung diseas ild | D003882;D017563 | T047 |
35,720,353 | uncov mast cell respons mycobacterium tuberculosi immunolog mechan contribut respons mycobacterium tuberculosi infect still repres challeng clinic manag scientif understand tuberculosi diseas scenario role differ cell involv host respons either term innat adapt immun remain key defeat diseas among coordin cell respons ... | D000086382;D009169;D014388 | T007;T047;T067 |
35,720,352 | novel immun base treatment diffus larg b cell lymphoma post car cell era prognosi patient refractoryrelaps rr diffus larg b cell lymphoma dlbcl poor immun base therapeut treatment cd chimer antigen receptor car cell therapi dramat chang treatment landscap rr dlbcl lead durabl remiss patient howev remain unmet need deve... | D016403;D013601 | T191;T025 |
35,720,351 | bacillus subtili express infecti pancreat necrosi virus vp protein retain immunostimulatori properti induc specif antibodi respons bacillus subtili document past year effect probiot differ aquacultur speci recogn benefici effect water qualiti fish growth immun status furthermor potenti vaccin adjuv also explor differ s... | D018175;D005393;D018061;D017686;D014765 | T047;T121;T013;T129;T005 |
35,720,350 | correl immun invas sar cov entri protein adam cancer patient bioinformat analysi sar cov caus covid pandem worldwid adam function disintegrin transmembran metalloproteinas domain protein involv regul sar cov receptor ace howev impact cancer patient infect covid correl immun cell infiltr unclear studi compar adam expres... | D000086382;D009369 | T191;T047;T067 |
35,720,349 | extend n termin domain confer atyp chemokin receptor properti cxcr b chemokin receptor cxcr play critic role immun cell recruit activ cxcr exist two main isoform cxcr cxcr b result altern splice although two isoform differ presenc n termin extens cxcr b attribut diverg function effect cell migrat prolifer cxcr b enigma... | D018925;D015398 | T043;T044;T116;T129 |
35,720,348 | bibliometr analysi innat immun dna sens cgas sting pathway cyclic guanosin monophosph gmp adenosin monophosph amp cgamp synthas cgas stimul interferon gene sting key compon innat immun system studi aim evalu research cgas sting pathway predict hotspot develop trend field use bibliometr analysi | D007371;D008565 | T116;T192;T121;T123;T129 |
35,720,347 | rapamycin dampen inflammatori properti bone marrow ilc il induc eosinophil airway inflamm alarmin cytokin interleukin il play import proinflammatori role type immun act type innat lymphoid cell ilc type helper h cell eosinophil inflamm asthma mechanist target rapamycin mtor signal pathway drive immun respons sever infl... | D001249;D004802 | T047 |
35,720,346 | compar immunogen bacteri express solubl trimer nanoparticl display influenza hemagglutinin stem immunogen current influenza vaccin need updat annual due mutat globular head viral surfac protein hemagglutinin ha address vaccin candid design base relat conserv ha stem domain shown protect efficaci anim model oligomer ant... | D007252;D007251;D053758 | T047;T073;T121;T109;T129 |
35,720,345 | comput structur predict antibodi antigen complex hydrogen deuterium exchang mass spectrometri challeng outlook although comput structur predict great success recent year regular fail predict interact larg protein complex residu level accuraci even correct orient protein partner perform comput dock notabl enhanc incorpo... | D041961;D000080307 | T059 |
35,720,344 | balbc ighv refer set defin haplotyp analysi long read vdj c sequenc f balbc x cbl mice immunoglobulin gene inbr mous strain common use model antibodi mediat human diseas poor character compromis data analysi infer immunoglobulin gene balbc mice use long read smrt sequenc amplifi vdj c sequenc f balbc x cbl hybrid anim ... | D007143;D007135 | T116;T129 |
35,720,343 | decoy receptor suppress cell prime promot apoptosi effector cell acut cell mediat reject role revers signal decoy receptor dcr belong tumor necrosi factor tnf receptor superfamili neutral tnf ligand includ fasl trail prevent activ cell prime howev cellular mechan under acut cell mediat reject acmr remain unknown | D053323;D047888 | T129;T116;T192 |
35,720,342 | sandfli fever virus attenu type interferon respons target phosphoryl jak stat compon sandfli fever virus emerg phlebovirus typic caus mild febril ill strain howev caus sever occasion fatal neuro invas diseas like virus phlebovirus devis various strategi inhibit type interferon ifn respons support product infect still s... | D007370;D010217;D016856 | T047;T116;T121;T129;T005 |
35,720,341 | function viroporin viral life cycl regul host cell respons viroporin viral encod transmembran protein essenti viral pathogen particip various stage viral life cycl therebi promot viral prolifer viroporin multifacet effect host cell biolog function includ alter cell membran permeabl trigger inflammasom format induc apop... | D000086082;D014780 | T005;T123;T116 |
35,720,340 | hear loss main clinic present nlrp associ autoinflammatori diseas nlrp gene mutat caus autosom domin autoinflammatori disord nlrp aid recent hear loss hl found sole major manifest nlrp aid test autosom domin hl famili custom panel hl gene found one famili carri nlrp cc g pserarg mutat function studi reveal novel varian... | D003638;D034381;D056660 | T047;T184;T033 |
35,720,339 | recombin acetylcholin receptor subunit extracellular domain promis new drug candid treatment myasthenia gravi myasthenia gravi mg cell depend antibodi mediat autoimmun diseas nicotin acetylcholin receptor achr major autoantigen compris sever b cell auto epitop hypothes efficaci drug candid antigen specif therapi mg com... | D020720;D011978 | T050;T116;T192 |
35,720,337 | target pcsk amelior graft vascular diseas mice inhibit nlrp inflammasom activ vascular smooth muscl cell graft vascular diseas gvd limit long term surviv patient solid organ transplant associ immun respons nonimmun factor includ dyslipidemia recent studi shown inhibit proprotein convertas subtilisinkexin type pcsk us f... | D000071449;D014652 | T047;T126;T116 |
35,720,336 | clinic variabl deep learn radiom featur help predict prognosi adult anti n methyl aspart receptor enceph earli two center studi southwest china develop fusion model combin clinic variabl deep learn dl radiom featur predict function outcom earli patient adult anti n methyl aspart receptor nmdar enceph southwest china | D060426;D000077321 | T047;T066 |
35,720,335 | chang system regulatori cell effector cell monocyt popul associ earli life stunt stunt environment enter dysfunct eed may respons alter gut system immun respons howev impact circul immun cell popul remain poor character earli life detail flow cytometri analysi major system immun cell popul stunt non stunt year old chil... | D009000;D050378 | T025 |
35,720,334 | cryptococcus neoforman infect induc il product promot stat phosphoryl cd cell cryptococcus neoforman infect central nervous system sever infecti diseas poor outcom high mortal estim new case year c neoforman mening case diagnos aid patient cd cell count cellsl howev mechan cryptococc mening patient normal immun functio... | D000163;D003453;D003455;D016919 | T047;T004 |
35,720,333 | non code rnas novel regul neuroinflamm alzheim diseas alzheim diseas ad one common caus dementia although signific breakthrough made understand progress pathogenesi ad remain worldwid problem signific public health burden thus effici diagnost therapeut strategi urgent requir latest research studi reveal neuroinflamm cr... | D000544;D035683;D062085 | T047;T123;T048;T114 |
35,720,332 | mechan caus acantholysi pemphigus lesson human skin pemphigus vulgari pv autoimmun bullous skin diseas caus primarili autoantibodi pv igg desmosom adhes protein desmoglein dsg dsg pv patient lesion character flaccid blister ultrastructur defin hallmark includ reduct desmosom number size format split desmosom well uncou... | D010392 | T047 |
35,720,331 | drosophila relish activ lncrna cr transcript facilit antimicrobi peptid express imd innat immun respons long noncod rnas lncrnas emerg class regul play crucial role regul strength durat innat immun howev littl known regul drosophila innat immun relat lncrnas studi first reveal overexpress lncrna cr could strengthen exp... | D029721;D062085 | T123;T116;T114 |
35,720,330 | antimicrobi resist covid landscap opportun anti infect antibodi antimicrobi peptid although covid captur public health attent antimicrobi resist amr disappear prevent escap resist microorgan anim environment reservoir one health approach desir context covid amr probabl affect inappropri use antibiot increas use antimic... | D000890;D000086382 | T121;T047;T067 |
35,720,329 | low level factor h famili protein meningococc diseas indic system process rather specif deplet neisseria meningitidi neisseria meningitidi causat agent meningococc diseas md evad complement mediat clearanc upon infect hijack human complement regul factor h fh fh protein famili also compris homolog fh relat fhr protein ... | D006463;D008589;D009345 | T007;T047 |
35,720,328 | natur killer cell antibodi independ antibodi depend hiv control infect human immunodefici virus hiv left untreat typic lead diseas progress toward acquir immunodefici syndrom peopl live hiv plwh control virus level limit detect standard viral load assay without treatment repres exampl function hiv cure individu call el... | D015658;D015497 | T047;T005 |
35,720,327 | prognost signific immunolog role fbxo human cancer systemat pan cancer analysi f box protein fbxo essenti subunit ubiquitin protein ligas complex increas recogn exhibit import biolog effect regul tumor occurr progress present research intend systemat investig latent role fbxo prognosi immunolog function across cancer p... | D044783;D009369 | T191;T116 |
35,720,326 | dna damag respons evalu provid novel insight person immunotherapi glioma dna damag respons ddr profici princip mechan temozolomid tmz resist glioma accumul evid also suggest determin role ddr anticanc immun propos comprehens investig ddr landscap optim glioma treatment | D060890;D005910 | T191;T116;T129 |
35,720,325 | urin alcam pf vcam surpass convent metric identifi nephriti diseas activ childhood onset system lupus erythematosus serial kidney biopsi repeat evalu monitor lupus nephriti ln childhood onset system lupus erythematosus csle remain challeng thus non invas biomark need evalu perform ten urin protein marker divers natur i... | D015891;D008180;D008181 | T121;T047;T123;T116 |
35,720,324 | case report new onset rheumatoid arthriti follow covid vaccin effici protect coronavirus diseas covid achiev immun mrna base vaccin sever acut respiratori syndrom coronavirus sar cov howev effici immun respons novel virus vaccin accompani wide varieti side effect inde flare new onset autoimmun disord report soon covid ... | D001172;D001327;D000086382 | T047;T067 |
35,720,323 | larg scale transcriptom data analysi identifi kifc potenti therapeut target associ immun infiltr prostat cancer prostat cancer pca one preval cancer urinari system previous research kinesin famili member c kifc oncogen demonstr key role incid progress differ cancer howev kifc report pca combin data differ databas inclu... | D011471;D059467 | T191;T081;T086 |
35,720,322 | pre clinic autoimmun lupus relat self report questionnair immun dysregul distinguish relat develop incomplet classifi lupus clinic unaffect relat unaffect unrel individu system lupus erythematosus sle propel pathogen autoantibodi autoab immun pathway dysregul identifi popul risk reach classifi sle essenti curtail infla... | D015551;D008180 | T047;T046 |
35,720,321 | hsf protect sepsi induc acut lung injuri inhibit nlrp inflammasom activ import transcript factor heat shock factor hsf play endogen anti inflamm role bodi allevi multipl organ dysfunct caus sepsi contribut uncontrol inflammatori respons nlrp inflammasom supramolecular complex play key role immun surveil inflamm accompl... | D055371;D018805 | T047;T046;T037 |
35,720,320 | mechan covid relat protein spinal tuberculosi immun dysregul purpos articl investig mechan immun dysregul covid relat protein spinal tuberculosi stb | D000086382;D014399 | T047;T067 |
35,720,319 | case report immun checkpoint blockad plus interferon add antifung therapi treatment refractori covid associ pulmonari aspergillosi cerebr mucormycosi invas fungal diseas ifd still caus substanti morbid mortal new therapeut approach urgent need recent data suggest benefit checkpoint inhibitor ici report case diabet pati... | D000086382;D009091;D055732 | T047;T067 |
35,720,318 | humor cellular respons bntb booster follow two dose chadox ncov determin use three sar cov antibodi assay interferon gamma releas assay prospect longitudin studi healthcar worker data humor cellular respons bntb booster dose follow two dose chadox ncov vaccin seldom report aim studi assess posit rate three repres antib... | D000086382;D000086402 | T047;T067;T005 |
35,720,316 | kidney normotherm machin perfus use preserv techniqu model reperfus deliv novel therapi assess inflamm immun activ ischaemia reperfus injuri iri inevit process transplant result inflamm immun system activ alpha antitrypsin aat anti inflammatori properti normotherm machin perfus nmp use deliv therapi may help assess eff... | D007249;D007668 | T023;T046 |
35,720,315 | nanoscal coloc nk cell activ inhibitori receptor control signal integr natur killer nk cell respons depend balanc signal inhibitori activ receptor howev integr antagonist signal occur upon nk cell target cell interact fulli understood provid evid nk cell inhibit via inhibitori receptor lya depend relat coloc nanomet sc... | D055650;D055655 | T192;T116;T129 |
35,720,314 | sqle key enzym cholesterol metabol correl tumor immun infiltr immunotherapi outcom pancreat adenocarcinoma pancreat adenocarcinoma paad treatment refractori cancer poor prognosi accumul evid suggest squalen epoxidas sqle play pivot role develop progress sever cancer type human howev function under mechan sqle paad rema... | D000230;D035683;D010190 | T191;T123;T114 |
35,720,313 | molecular analysi memori b cell antibodi respons plasmodium falciparum merozoit surfac protein children adult uganda memori b cell mbcs plasma antibodi plasmodium falciparum pf merozoit antigen import compon protect immun respons malaria gain understand respons pf develop two arm humor immun system evalu mbc antibodi r... | D008288;D020066 | T047;T123;T116;T129 |
35,720,312 | tislelizumab plus chemotherapi sequenti neoadjuv therapi non ccr patient neoadjuv chemoradiotherapi local advanc esophag squamous cell carcinoma etnt exploratori studi esophag squamous cell carcinoma escc remain challeng malign tumor poor prognosi limit treatment method worldwid patient local advanc stage diagnosi high... | D000971;D004938;D000077277 | T191;T061 |
35,720,311 | car cell target membran bound hsp tumor cell mimic hsp prime nk cell strategi boost anti tumor immun urgent need treat therapi resist late stage cancer includ colorect cancer crcs cytokin stimul genet modif chimer antigen receptor car repres promis strategi specif redirect anti tumor activ effector cell like natur kill... | D007376;D009369 | T121;T191;T116;T129 |
35,720,310 | promis acinetobact baumannii vaccin candid drug target recent year parallel uncontrol use antibiot emerg multidrug resist bacteria like acinetobact baumannii pose sever threat baumannii predomin nosocomi set due abil persist hospit surviv antibiot treatment therebi eventu lead increas preval mortal due infect increas s... | D040981 | T007 |
35,720,309 | nlrp inflammasom inhibitor dapansutril attenu cyclophosphamid induc interstiti cystiti interstiti cystiti ic bladder pain syndrom bps hereaft refer togeth ic clinic syndrom character steril inflamm bladder etiolog pathophysiolog ic remain unclear may involv autoimmun light signific role play nlrp inflammasom howev effe... | D018856 | T047 |
35,720,308 | ferroptosi autoimmun diseas adequ control autoimmun diseas unclear etiolog result autoreactiv immun system remain major challeng one factor trigger autoimmun abnorm induct cell death inadequ clearanc dead cell lead exposur releas intracellular content activ immun system differ cell death subtyp apoptosi necroptosi auto... | D001327;D000079403;D008180 | T047;T043 |
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