PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
|---|---|---|---|
36,218,937 | medicar advantag financ qualiti puerto rico vs us state washington dc medicar beneficiari puerto rico enrol medicar advantag plan evid plan payment qualiti puerto rico compar us state washington dc hereaft refer us mainland lack notabl implement patient protect afford care act aca | D020398 | T089;T033 |
36,218,936 | comparison estim surpris act qualifi payment amount payment network network emerg medicin profession surpris act nsa took effect januari appli qualifi payment amount qpa network payment refer point understand qpa measur compar network network payment physician receiv nsa implement may use polici maker stakehold | D004635;D017048 | T091;T081 |
36,218,933 | comparison low valu servic among medicar advantag tradit medicar beneficiari low valu care medicar program preval cost potenti harm persist although medicar advantag plan use manag care strategi avail tradit medicar tm clear whether flexibl associ lower rate low valu care | D020398 | T089;T033 |
36,218,932 | associ medicaid dental payment polici children dental visit oral health school absenc although state medicaid program cover children dental servic less half public insur children receiv recommend care | D008484;D009909 | T064;T089;T033 |
36,218,927 | associ privat equiti acquisit physician practic chang health care spend util privat equiti acquisit physician practic us increas rapid howev implic health care deliveri spend unclear | D005102;D010820 | T097;T081 |
36,218,926 | associ insur mix diagnost code practic new york state hospit given higher reimburs rate hospit primarili serv privat insur patient may invest intens code hospit serv public insur patient may lead hospit code diagnos patient | D006783;D007341 | T078;T093;T081;T073 |
36,218,923 | raspberri like agbi pvp nanoparticl enhanc sonodynam chemodynam cancer therapi sonodynam therapi sdt non invas treatment prefer mani research ultrasound appli tumor lesion enrich sound sensit activ sound sensit produc reactiv oxygen speci ros kill tumor cell studi raspberri like agbi pvp nanoparticl nps prepar modifi polyvinylpyrrolidon pvp final agbi pvp nps nm diamet suitabl band gap success synthes nps could play role sdt generat ros induc ultrason stimul moreov agbi pvp nps could also catalyz h tumor microenviron produc oh equip nps chemodynam therapi cdt properti vivo vitro experi suggest compar singl treatment combin sdt cdt clearer inhibitori effect tumor cell | D065856;D053758;D009369 | T073;T002;T191;T168;T129 |
36,218,904 | tie innov evalu account program address intersect health social need jama forum advoc rigor assess effect program initi address health relat social need improv health outcom | D003256;D012941 | T054;T078;T052 |
36,218,371 | structur guid discoveri potent antifung prevent ras signal inhibit protein farnesyltransferas infect fungal pathogen difficult treat due pauciti antifung emerg resist next generat antifung therefor need urgent develop compound prevent farnesyl cryptoccoccus neoforman ras protein inhibit protein farnesyltransferas nanomolar affin farnesyl direct ras cell membran requir infect lethal pathogen fungus high affin compound inhibit fungal growth micromolar minimum inhibitori concentr mic fold better fluconazol antifung common use clinic compound bound distinct inhibit mechan two altern partial overlap bind site access via differ inhibitor conform show antifung potenc depend critic select inhibit mechan determin efficaci inhibitor low vivo level enzym farnesyl substrat elucid chemic modif antifung encod desir inhibitor conform concomit inhibitori mechan | D000935;D019883 | T121;T126;T116;T195 |
36,218,359 | influenc nutrient nativ communiti e coli surviv beach environ previous research identifi e coli popul persist freshwat beach sand distinct fecal pollut event work identifi factor influenc surviv e coli sand use laboratori microcosm replic beach condit microcosm deploy examin effect genet background competit nativ microbi communiti increas nutrient concentr e coli surviv surviv compar phylotyp b b howev defici stress respons great reduc surviv absenc nativ communiti nutrient condit compar observ sand e coli cell densiti remain within order magnitud initi concentr week incub increas nitrogen associ decreas decay rate first week increas carbon appear provid advantag later time point howev highest surviv found addit carbon nitrogen nativ sand seed fresh cladophora maintain higher concentr e coli compar sand contain decay cladophora cladophora find demonstr persist e coli popul sand affect avail carbon nitrogen abil regul stress presenc algal mat ie cladophora work suggest nativ microbi communiti may modul surviv outcompet e coli nutrient import current monitor fecal pollut account persist e coli popul freshwat sand result higher concentr water threat human health present work examin driver persist e coli popul sand aid beach manag techniqu examin influenc nutrient includ local sourc strand cladophora e coli popul found major determin e coli surviv freshwat beach sand addit nutrient specif carbon nitrogen concentr fold higher baselin concentr beach work provid framework identifi pollut sourc promot e coli surviv sand character carbon nitrogen content incorpor beach manag techniqu improv knowledg begin understand e coli fluctuat water due resuspens sand water | D001493;D000460 | T083;T002 |
36,218,358 | human cytomegalovirus util multipl viral protein regul basement membran protein nidogen nidogen nid import basement membran protein secret mani cell type previous found human cytomegalovirus hcmv infect rapid induc chromosom break basement membran protein nid encod near q break site downregul determin specif break regul nid rather interact sever viral protein cellular machineri dna regul nid screen batteri viral protein present hour postinfect hpi regul induc includ compon incom virion immedi earli ie protein adenovirus ad deliveri tegument protein pp ul ie protein ie influenc steadi state ss nid level ie mechan regul unclear ul influenc proteasom regul ss nid real time quantit pcr rt qpcr experi determin pp downregul nid transcript surpris wf fibroblast clone express minut quantiti pp suppress nid transcript effici hcmv infect result near absenc ss nid sequenc analysi region surround q break site nid promot reveal ccctc bind factor ctcf bind site chromatin immunoprecipit experi determin pp ctcf bound two site hcmv infect express pp alon replic bind bind observ earli hpi coloc pp ctcf occur quick min postinfect pi infect cell nuclei fibroblast ctcf knock adpp infect decreas nid transcript ss nid protein level result emphas anoth aspect pp activ infect identifi viral protein key contributor hcmv effort elimin nid show first time direct interact pp cellular genom import found human cytomegalovirus hcmv util multipl viral protein multipl pathway regul ubiquit cellular basement membran protein nidogen nid extent resourc redund method virus evolv affect control strong suggest remov provid life cycl advantag hcmv discoveri one protein hcmv use control nid pp bind direct cellular dna exert control present vanish small quantiti may broad implic wide rang infect scenario dysregul nid immunocompet host known manifest complic infect howev naiv immun system develop fetus disrupt development critic protein could initi catastroph hcmv induc birth defect | D003587;D017874 | T116;T123;T005 |
36,218,355 | biochem regulatori analys xylanolyt regulon caldicellulosiruptor bescii reveal genus wide featur hemicellulos util caldicellulosiruptor speci scaveng carbohydr runoff contain plant biomass enter hot spring grass grow moder part thermal featur caldicellulosiruptor speci degrad cellulos known speci hemicellulolyt well character speci caldicellulosiruptor bescii decentr hemicellulas inventori across five differ genom loci two isol gene transcriptom analys compar genom enzymat character util assign function role determin relat import six putat endoxylanas five glycosid hydrolas famili gh enzym one gh enzym two putat exoxylanas one gh one gh c bescii two genus wide conserv xylanas c bescii xyna gh c bescii xyla gh highest level sugar releas oat spelt xylan top gene transcrib c bescii high induc xylan compar cellulos indic minim set enzym use drive xylan degrad genus caldicellulosiruptor complement hemicellulolyt inventori tune specif form hemicellulos avail plant biomass point synerg studi reveal pair specif gh famili protein gh c bescii gh protein releas sugar vitro mixtur contain five differ gh protein overal work demonstr essenti requir caldicellulosiruptor degrad various form xylan differ speci genom inventori tune surviv uniqu biotop variabl lignocellulos substrat import microbi deconstruct lignocellulos product biofuel chemic requir hydrolysi heterogen hemicellulos access microcrystallin cellulos portion work extend previous vivo vitro effort character hemicellulos util integr genom reconstruct transcriptom data operon structur biochem characterist key enzym understand deploy function hemicellulas extrem thermophil caldicellulosiruptor bescii furthermor compar genom genus reveal conserv diverg mechan hemicellulos util across sequenc speci therebi pave way connect function enzym character metabol engin effort enhanc lignocellulos convers | D018085;D014990 | T109;T028 |
36,218,352 | circmedl protect hydrogen peroxid induc apoptot oxid injuri human len epitheli cell mir palcam axi cataract lead caus visual impair revers blind despit advanc surgic remov cataract cataract continu lead public health issu due complic surgeri circular rnas circrna show implic pathophysiolog age relat cataract arc herein work elucid role mechan circmedl process arc | D002386;D035683 | T047;T123;T114;T190;T033 |
36,218,348 | impact cumul complic year treatment relat healthcar cost patient colorect periton metastas undergo cytoreduct surgeri hypertherm intraperiton chemotherapi aim studi evalu impact minor major complic treatment relat healthcar cost patient undergo cytoreduct surgeri crs hypertherm intraperiton chemotherapi hipec treatment colorect periton metastas pms | D015179;D006979;D010534 | T191;T061 |
36,218,347 | ultra small wearabl flexibl biosensor continu sweat analysi field wearabl sens small precis sensor great reduc burden wearer improv sens experi futur direct sens develop herein introduc ultra small wearabl biosensor system integr ms chip real time high accur sweat detect whole system main includ flexibl electrod print circl board pcb size pcb cm cm great minim size sweat system improv wear comfort notabl miniatur system compar commerci electrochem workstat ensur reliabl accuraci real time analysi core process ms chip dimens mm mm use perform electrochem signal process perform electrochem character measur ultra small wearabl biosensor system bodi monitor four biomark glucos lactat na k sweat human volunt success achiev help electrochem sensor system mass biochem data perspir acquir better understand bodi respons daili activ facilit earli predict abnorm physiolog chang futur | D000076251;D015374 | T059;T075;T073 |
36,218,339 | develop gold phosphoresc tweezer sens applic synthesi gold alkynyl fluoren compound contain diphosphan dppb bisdiphenylphosphanebutan easili achiev treatment previous synthes ethynylfluoren au n polym correspond dppb diphosphan adequ stoichiometri compound show boat tweezer conform make ideal use host molecular recognit process differ polyaromat hydrocarbon pah polyfluorin compound pfcs use guest stronger interact detect pah especi anthracen agreement spectrofluorometr titrat calcul valu associ constant confirm dft calcul compound immobil differ organ matric order enhanc room temperatur phosphoresc rtp promot sens dual emiss furthermor case analyt investig phosphoresc observ rang wavelength coincid fluoresc emiss pah pfcs | D006046;D006841 | T121;T109;T196 |
36,218,325 | tp mutat myelodysplast syndrom acut myeloid leukemia biolog current therapi futur direct tp mutat myelodysplast syndrom mds acut myeloid leukemia aml form distinct group myeloid disord dismal outcom tp mutat mds aml lower respons rate either induct chemotherapi hypomethyl agent base regimen venetoclax base therapi compar non tp mutat counterpart poor median overal surviv month recent advanc identifi novel pathogen mechan tp mutat myeloid malign potenti improv treatment strategi distinct clinic subgroup review discuss recent insight biolog tp mutat mdsaml current treatment emerg therapi includ immunotherapeut nonimmun base approach entiti | D009190;D015470 | T191;T046 |
36,218,311 | post remedi oxygen suppli new perspect photodynam therapi suppress tumor metastasi photodynam therapi pdt hold great promis tumor therapi due high safeti efficaci specif howev risk increas metastasi hypox tumor oxygen depend pdt remain underestim propos post pdt oxygen suppli pos strategi reduc risk metastasi herein biocompat tumor target ce bsa pfc bsa nanoparticl construct pdt pos orthotrop breast cancer model pdt ce bsa nanoparticl increas tumor metastasi via hif signal pathway wherea pos signific reduc pdt trigger metastasi block pathway furthermor pos clinic protocol fda approv photosensit hypericin oxygen inhal reduc pdt induc metastasi studi find indic pdt may increas risk tumor metastasi pos may solv problem pos reduc metastasi result pdt also oxygen depend treatment radiotherapi sonodynam therapi | D010778;D053758 | T061;T073 |
36,218,307 | nanostar carri multifunct neurotroph dendrim protect neuron preclin vitro model neurodegen disord challeng neurolog lack effici brain penetr neuroprotect target multipl diseas mechan plasmon gold nanostar promis candid deliv standard care drug insid brain trial carrier neuroprotect conjug custom made peptid dendrim term hh encompass motif neurotroph sa protein onto star shape spheric gold nanostructur hh aunsaunp evalu potenti neuroprotect interact neuron hh nanostructur cross model blood brain barrier bound plasma membran induc neuritogenesi aun show higher potencyefficaci aunp h aunsnp protect neuron oxid stress h aun potent parkinson alzheim diseas pdad relat cytotox unconjug sa motif also decreas amyloid beta induc neurodegener introduc sa player ad use custom made dendrim coupl star shape nanoparticl promis rout activ multipl neuroprotect pathway increas drug potenc treat neurodegen disord | D018696;D050091;D000544 | T047;T122;T121;T048;T169;T104 |
36,218,306 | technic aspect total endoscop robot assist pericardi cyst resect pericardi cyst rare mediastin mass often diagnos incident find symptomat patient suspicion malign may warrant surgic resect video tutori demonstr technic aspect total endoscop robot assist pericardi cyst resect approach allow definit treatment safe procedur small surgic wound short hospit stay fast recoveri almost postop limit | D008476;D065287 | T191;T061;T047 |
36,218,305 | rhd genotyp resolv weak discrep rhd patient phenotyp institut rhd genotyp transfus servic obstetr patient transfus candid sought examin rhd genotyp resolv weak discrep autom micropl direct agglutin mda rhd phenotyp impact need rh immun globulin rhig negat rbcs | D012204;D001803 | T022;T061;T109;T129 |
36,218,304 | intern aortic annuloplasti remodel ring bicuspid aortic valv repair differ phenotyp describ approach base use intern bicuspid annuloplasti ring provid annular reduct also routin achiev valv symmetri haart ring circular base geometri subcommissur post size accord intercommissur diamet keep dimens unchang non fuse leaflet serv refer free edg length measur ball sizer predict requir ring diamet free edg diamet transannular sutur ring bring sinus sinus dimens central improv leaflet coaptat import ring remodel fuse nonfus sinus equal annular segment therebi increas mobil fuse segment facilit later plicat way ring establish valv geometri | D001022;D000082882;D058385 | T061;T047;T019 |
36,218,300 | surgic repair adult form scimitar syndrom scimitar syndrom various clinic present anatom featur case diagnos adulthood reconstruct use autolog tissu rerout right pulmonari venous blood flow left atrium ideal howev scimitar vein drain caudal segment inferior vena cava reconstruct use prosthet materi may necessari due distanc left atrium scimitar vein describ case year old boy scimitar syndrom anastomos scimitar vein right atrium use artifici graft creat atrial septal defect rerout right pulmonari venous blood left atrium year sinc procedur patient experienc graft stenosi thromboembol event | D006344;D011667;D012587 | T023;T019;T047 |
36,218,298 | robot singl right anterior medial sb subsegmentectomi earli primari lung cancer patient small physiqu subsegmentectomi option treatment earli primari lung cancer present without adequ surgic margin wedg resect previous report regard robot singl subsegmentectomi report robot singl subsegmentectomi right anterior medial subseg sb lung parenchyma dissect vessel sealer extend along intersubsegment vein proper lung mobil solv direct limit robot stapler addit insert ventral port subcost region increas distanc port perform robot singl subsegmentectomi challeng howev techniqu help achiev safe effect oper | D008175;D065287 | T191;T061 |
36,218,297 | foreign bodi remov lung spare bronchotomi tutori show remov aspir foreign bodi via lung spare oper use transvers bronchotomi transthorac approach year old woman admit treatment aspir foreign bodi pushpin impact subsegment branch right lower lobe bronchus problem manag success use conserv surgic approach foreign bodi remov lower lobe bronchus therebi avoid need lung resect start posterolater thoracotomi harvest pedicl flap surgeon expos open bronchus remov impact foreign bodi bronchial sutur cover pedicl flap endoscop remov aspir foreign bodi consid first line treatment challeng lead airway injuri stenosi describ begin th centuri transthorac bronchotomi foreign bodi remov remain life save lung spare procedur overlook | D001999;D005547 | T037;T061;T060;T020;T072 |
36,218,296 | sutur map endoscop tricuspid valv repair minim invas tricuspid surgeri use complet endoscop approach steep learn curv purpos creat sutur map allow placement sutur minim tissu handl improv oper effici process use surgeon begin learn minim invas surgeri earli stage endoscop surgic career | D006348;D019918;D014262 | T061;T047 |
36,218,295 | primari closur sternal cleft neonat period sternal cleft rare malform midlin fusion sternal bar common form superior partial defect surgic correct primari closur gold standard recommend procedur perform month age greater complianc maxim flexibl thorac wall featur ensur safer repair low risk complic allow less extens procedur requir use addit techniqu midlin incis perform anterior thorac wall major pectorali flap rais main surgic goal chang remain sternum u v shape transfix interrupt sutur place cartilagin border midlin closur hemodynam ventil monitor time closur perform layer | D009139;D035441 | T023;T019 |
36,218,294 | hemiclamshel approach left pneumonectomi hemiclamshel clamshel incis virtual forgotten sinc introduct cardiac surgeri median sternotomi exhilar advanc minim invas thorac surgeri howev rare clinic scenario larg space occupi lesion thorac caviti surgeon resort clamshel hemiclamshel approach achiev complet exposur remov larg mass thorac caviti video tutori demonstr oper step hemiclamshel approach clinic scenario left pneumonectomi tnm non small cell lung cancer | D002289;D008175 | T191 |
36,218,293 | sutur map endoscop mitral valv replac mitral valv replac use endoscop approach advanc skill procedur purpos creat sutur map mitral valv replac allow placement sutur least tissu manipul sutur map serv guid train purpos surgeon earli stage endoscop surgeri | D019918;D008944;D066231 | T061;T047;T097 |
36,218,292 | doubl intrathorac arteri cannul plus peripher cannul whole bodi perfus infant report techniqu distal bodi perfus infant hypoplast aortic arch isthmus stenosi ultrasound guid cannul femor arteri use intra arteri vascular sheath establish whole bodi perfus tripl cannul | D001013;D001017 | T023;T019;T047 |
36,218,290 | enantiocontrol access intermedi high function clovan type terpenoid formal synthesi rumphellclovan e describ enantiocontrol rout versatil intermedi synthesi high function clovan type terpenoid synthet rout commenc r carvon commerci avail enantioenrich build block oxygen strategi use concis access clovan scaffold one exampl versatil obtain intermedi formal synthesi rumphellclovan e | D013729 | T109;T123 |
36,218,287 | direct c h alkyl structur divers alcohol via combin tavaborol photoredox catalysi herein report method use antifung tavaborol co catalyst direct c h alkyl structur divers alcohol photoredox catalysi protocol featur mild condit remark scope wide function group toler allow construct wide array high function alcohol includ homoserin deriv c glycosyl amino acid also demonstr synthet applic methodolog late stage function pharmaceut natur product | D000438;D001688 | T121;T109;T123 |
36,218,284 | applic secondari electrospray ionize coupl high resolut mass spectrometri chemic character thermal generat aerosol inhal rout administ drug dietari supplement garner signific attent past decad perform real time analys aerosol use secondari electrospray ionize sesi technolog interfac high resolut mass spectrometri hrms primarili develop exhal breath analysi goal detect main aerosol constitu sever commerci avail inhal devic contain caffein melatonin cannabidiol vitamin b test chemic character aerosol produc devic enabl detect main constitu screen potenti contamin byproduct impur aerosol addit programm syring pump connect sesi hrms system monitor aerosol activ pharmaceut ingredi api chloroquin hydroxychloroquin azithromycin setup allow us detect caffein melatonin hydroxychloroquin chloroquin cannabidiol produc aerosol azithromycin vitamin b aerosol could detect howev instrument setup enabl detect vitamin b breakdown product generat aerosol process posit control realiz liquid chromatographi hrms analys compound detect aerosol confirm exact mass measur proton andor deproton speci well respect collis induc dissoci tandem mass spectra result reveal potenti wide applic technolog real time monitor aerosol activ pharmaceut ingredi administ inhal rout | D008550;D002185 | T121;T109;T125 |
36,218,280 | identif monomethyl branch chain lipid combin liquid chromatographi tandem mass spectrometri charg switch chemistri various mass spectrometr approach appli lipid analysi unravel extens structur divers lipid remain signific challeng notabl approach often fail differenti isomer lipidsa challeng particular acut branch chain fatti acid fas often share similar ident mass spectra straight chain isom util charg switch strategi combin ligat magnesium dicat deproton fatti acid anion subsequ activ charg invert anion yield mass spectra differenti anteiso branch straight chain iso branch chain fa isom predict fragment enabl de novo assign anteiso branch point applic charg invers chemistri gas solut phase modal demonstr assign posit anteiso methyl branch point fas aid liquid chromatographi extend de novo assign addit branch site via predict fragment pattern methyl branch site move closer carboxyl carbon gas phase approach shown compat top structur elucid complex lipid phosphatidylcholin integr solut phase charg invers revers phase liquid chromatographi enabl separ unambigu identif fa structur within isomer mixtur taken togeth present charg switch ms base techniqu combin liquid chromatographi enabl structur identif branch chain fa without requir authent methyl branch fa refer standard | D053719;D005227 | T109;T123;T063;T168 |
36,218,265 | myosin b requir proper local intermicrovillar adhes complex intestin brush border intestin enterocyt elabor apic membran actin rich protrus known microvilli organ microvilli orchestr intermicrovillar adhes complex imac connect distal tip adjac microvilli imac compos cdhr cdhr well scaffold protein ushc anksb myosin b myob creat imac cell must transport protein apic membran myosin b myob molecular motor traffic ion transport apic membran enterocyt hypothes myob may also respons local imac protein address question use two differ mous model neonat germlin myob knockout myob ko mice adult intestin specif tamoxifen induc villincr ert myob floxflox mice control mice immunostain reveal cdhr cdhr ushc myob high enrich tip microvilli contrast neonat germlin adult myob defici mice show loss apic cdhr cdhr myob brush border accumul subap compart coloc analysi reveal decreas mander coeffici adult induc myob defici mice compar control mice cdhr cdhr ushc myob scan electron microscopi imag demonstr aberr microvilli pack adult induc myob defici mous small intestin data indic myob respons deliveri imac compon apic membran new noteworthi intestin epithelium absorb nutrient water elabor apic membran high organ microvilli microvilli organ regul intermicrovillar adhes complex creat link neighbor microvilli control microvilli pack densiti studi report new traffick partner imac myosin b loss myosin b result disorgan brush border failur imac protein reach distal tip microvilli | D020895;D008871;D024701 | T025;T026;T126;T116 |
36,218,259 | teeth macroabras determin dental age diet illyrian popul kopila necropoli island korula croatia paper present chang caus macroabras teeth skelet remain found tomb west necropoli archeolog site kopila near blato island korula site archeolog date back late iron age island inhabit illyrian aim studi assess dental age buri individu death determin type diet could give us preliminari insight socio econom standard inhabit settlement analyz sampl part collect excav skelet remain kept vela luka cultur center island korula perman teeth fragment maxilla fragment mandibl found tomb classifi individu sex teeth analyz metric non metric method determin dental status order assess dental age time death diet inhabit dental age individu determin lovejoy method degre tooth wear smith knight method analysi stabl isotop c determin exact time death analyz individu tooth wear chang pronounc present teeth equal incisor molar p signific gender differ p teeth jaw part differ degre tooth wear teeth mandibl maxilla p degre tooth wear teeth maxilla right left p degre tooth wear teeth mandibl right left p averag age analyz popul sampl year buri bc tooth wear chang observ analyz teeth indic diet rich hard weak cariogen food particl probabl inorgan origin caus increas wear tooth structur popul sedentari agricultur type life expect normal late iron age besid socio econom status good age time death year studi includ accur standard method assess condit | D000071298;D057085 | T023;T037 |
36,218,258 | physic disabl late antiqu milan slip capit femor epiphysi sever secondari joint diseas basilica san dionigi paper present skelet remain adult male year bone lesion deform left hip recov archaeolog excav former basilica san dionigi date late antiqu rd th centuri ad milan biolog profil paleopatholog analysi perform follow standard refer bone underw radiolog examin differenti diagnosi includ congenit anomali activ ricket infecti diseas femor neck trauma legg carv perth diseas slip capit femor epiphysi sfce osteogenesi imperfecta osteoporosi lesion high consist legg calv perth diseas typic sfce complic avascular necrosi secondari osteoarthrosi alter femor head led leg length discrep caus gait alter partial compens though increas muscular activ right leg reduc mobil joint potenti hip pain difficulti walk run even limp paper explor case physic disabl roman era found near christian place worship repres rare case sfce paleopatholog record | D060048;D007873;D010003 | T047 |
36,218,256 | osteoclast mediat resorpt prime skeleton success integr axolotl limb regener earli event axolotl limb regener includ immun respons format wound epithelium event link clearanc damag tissu prior blastema format regener miss structur report resorpt calcifi skelet tissu activ cell driven high regul event process carri osteoclast essenti success integr newli form skeleton inde extent resorpt direct correl integr effici treatment zoledron acid result osteoclast function inhibit fail tissu integr moreov identifi wound epithelium regul skelet resorpt like releas signal involv recruitmentdifferenti osteoclast final report correl resorpt blastema format particular coordin resorpt cartilag condens sum result identifi resorpt major event upon amput play critic role overal process skelet regener | D000558;D010010 | T025;T011 |
36,218,255 | guillain barr syndrom thrombocytopenia sar cov vaccin moderna case report massiv vaccin sar cov virus demonstr one major measur reduct morbid mortal virus caus howev last month administr vaccin also associ rare life threaten advers effect | D000086382;D000086663;D020275;D013921 | T047;T200;T067 |
36,218,254 | central nervous system infect bacillus cereus case report literatur review bacillus cereus ubiquit pathogen usual produc self limit gastrointestin symptom howev suscept patient lead central nervous system infect potenti fatal | D001922;D054198 | T191;T047 |
36,218,253 | paediatr status epilepticus status epilepticus defin situat result failur mechan respons termin epilept seizur oper concept adopt intern two time identifi first time treatment must begin five minut convuls status minut focal non convuls status second time consid high risk subsequ sequela minut case convuls occur children per year refractori super refractori case | D000777;D004827;D007649;D015742;D013226 | T047;T121;T109;T039;T033 |
36,218,252 | toward earli differenti diagnosi autism spectrum disord fragil x syndrom systemat review near diagnos fragil x syndrom show comorbid autism thus similar differ condit lead differ clinic manifest howev earli differenti diagnosi may help profession detect deficit enhanc strength appli best suitabl intervent purpos scope review provid comprehens overview relat differ autism fragil x syndrom orient diagnosi intervent | D000067877;D001321;D005600 | T047;T048 |
36,218,251 | effect psychotherapeut intervent group program improv caregiv well alzheim diseas patient famili caregiv cuidem studi caregiv patient alzheim diseas experi physic emot burnout treat non pharmacolog intervent | D000544;D017028 | T047;T098;T099;T048;T097 |
36,218,247 | ez clear simpl rapid robust mous whole organ clear tissu clear whole organ cell profil revolution biolog imag explor organ three dimension space without compromis tissu architectur complic labori procedur expens equip well use hazard organ solvent prevent widespread adopt method report simpl rapid tissu clear method ez clear clear whole adult mous organ hr three simpl step sampl stay room temperatur remain hydrat throughout clear process preserv endogen synthet fluoresc without alter sampl size wholemount clear imag sampl process ez clear subject downstream applic tissu embed cryosect follow standard histolog immunofluoresc stain without loss fluoresc signal endogen synthet report furthermor demonstr wholemount adult mous brain process ez clear success immunolabel fluoresc imag still retain signal endogen fluoresc report overal simplic speed flexibl ez clear make easi adapt implement divers imag modal biomed research | D004396;D021621 | T073;T060;T109;T130;T197;T062 |
36,218,242 | mandibular implant overdentur clinic report novel design report use mandibular implant overdentur novel implant distribut oppos maxillari complet dentur rehabilit older edentul patient | D015921;D009066 | T074;T033 |
36,218,234 | variat ubiquitin system gene creat substrat specif effect proteasom protein degrad precis control protein degrad critic life yet natur genet variat affect essenti process larg unknown develop statist power map approach character genet variat affect protein degrad ubiquitin proteasom system up use yeast saccharomyc cerevisia systemat map genet influenc n end rule up pathway protein n termin amino acid function degrad promot signal across possibl n termin amino acid identifi genom loci influenc up activ mani pathway substrat specif effect fine map four loci identifi multipl causal variant four ubiquitin system gene whose product process nta recogn ubr doa ubiquitin ubc cellular protein cis act promot variant modul up activ alter ubr express alter abund protein without affect level correspond mrna transcript result reveal complex genet basi variat up activ | D025801;D029701 | T123;T116 |
36,218,230 | preconcept health optim women polycyst ovari syndrom find time polycyst ovari syndrom pcos common endocrin disord among reproduct age women common caus infertil among women major contributor pregnanc complic | D011085;D047928;D011248 | T047;T046 |
36,218,229 | use anti mllerian hormon understand ovulatori dysfunct polycyst ovarian syndrom aim review understand anti mllerian hormon amh contribut ovulatori dysfunct polycyst ovarian syndrom pcos | D011085;D000858;D036361 | T047;T116;T125 |
36,218,224 | optim assist reproduct technolog outcom patient polycyst ovarian syndrom updat unansw question narrat review recent literatur optim assist reproduct technolog outcom patient polycyst ovarian syndrom pcos | D011085;D016471 | T047 |
36,218,221 | epigallocatechin gallat allevi galactos induc age impair via gut brain communic studi aim determin whether gut brain communic could modul epigallocatechin gallat egcg mous age model establish daili inject galactos gal week result show egcg could improv age associ chang increas immun organ index brain index learn memori abil vivo egcg trigger age prevent associ reduct lipid peroxid elev enzymat non enzymat antioxid activ brain concomit treatment gal induc age mice egcg signific reduc corticotropin releas hormon adrenocorticotrop hormon corticosteron suggest egcg exert protect age brain involv inhibit hypothalam pituitari adren hpa axi data concern intestin function show egcg could enhanc fecal moistur vitro reduc ph valu fece age mice compar gal group suggest egcg play benefici role intestin age mice moreov short chain fatti acid scfas mediat gut brain communic signific increas intestin content age mice treatment egcg therefor tea polyphenol egcg show anti age properti demonstr implic modul gut brain communic attenu hpa axi enhanc content scfas | D005690;D002392 | T121;T109;T123 |
36,218,216 | multimod imag acut myocard diagnosi acut myocard often involv sever noninvas techniqu provid inform regard volum eject fraction tissu character particular echocardiographi extrem help evalu biventricular volum strain eject fraction cardiac magnet reson beyond biventricular volum strain eject fraction allow character myocardi tissu provid inform regard edema hyperemia fibrosi contemporari cardiac comput tomographi angiographi ccta extrem import assess coronari arteri pulmonari arteri aorta also tissu character use ccta addit tool explain chest pain diagnosi myocard | D009205 | T047 |
36,218,215 | advanc cerebr perfus imag techniqu acut ischem stroke applic cerebr perfus imag demonstr signific assess benefit abil establish appropri triag patient acut ischem stroke ai larg arteri occlus lao extend time window comput tomographi perfus ctp magnet reson imag mri routin use determin ischem core well tissu risk aid therapeut decis make howev time requir transport patient imag extend door reperfus time c arm cone beam ct cbct novel tomographi technolog combin radiographi ct imag base digit subtract angiographi platform comparison ct mri perfus techniqu cbct combin catheter angiogram therapi serv one stop shop diagnosi treatment ai great reduc door reperfus time review current evid efficaci theoret basi cbct well perfus techniqu purpos assist clinician establish effect repaid workflow patient ai lao clinic practic | D002545;D000083242;D020521 | T047;T046 |
36,218,214 | aortic regurgit multimod approach aortic regurgit ar common valvular patholog multimod noninvas cardiovascular imag routin use assess mechan ar degre hemodynam impact cardiovascular system collect inform crucial establish prognosi guid patient manag follow echocardiographi remain primari test assess ar comprehens assess valvulopathi obtain combin inform differ techniqu state art review intend provid updat ed overview applic strength limit transthorac echocardiographi cardiac magnet reson cardiac comput tomographi patient ar | D001022;D006349 | T047 |
36,218,213 | atrial thrombosi left think also right atrial fibril af common arrhythmia general popul system thromboembol left atrial appendag laa thrombosi well known complic af wherea thromboembol complic right atrial ra thrombus infrequ nevertheless preval ra thrombosi debat despit low preval echocardiograph studi higher preval found autopt studi rise hypothesi detect ra clot possibl relat limit evalu right atrial appendag raa non invas imag present review current literatur ra thrombosi regard diagnosi differenti best treatment option | D020517;D001281;D006331;D013927 | T023;T046;T047 |
36,218,212 | novel nuclear medic procedur detect microvascular dysfunct coronari microvascular dysfunct present two third patient show symptom sign myocardi ischemia microcircul abnorm due endotheli smooth muscl cell dysfunct impair mechan caus high risk advers cardiovascular event diagnos coronari microvascular dysfunct challeng guidelin recommend use nuclear medicin procedur mention indic myocardi perfus imag positron emiss tomographi novel procedur high diagnost accuraci qualiti imag short acquisit low effect radiat dose prognost factor still unknown procedur benefit | D003324;D017202;D055414 | T047;T060 |
36,218,211 | transcrani doppler ultrasound clinic applic neurolog cardiolog set transcrani doppler tcd ultrasonographi rapid noninvas real time low cost imag techniqu perform low frequenc mhz probe order evalu cerebr blood flow cbf patholog alter specif acoust window recent year tcd use expand across mani clinic set actual widespread indic tcd exam repres diagnosi paradox embol due patent foramen oval young patient cryptogen stroke addit tcd also found use applic neurolog care set includ follow cerebr vasospasm follow acut subarachnoid hemorrhag brain trauma cerebrovascular atherosclerosi evalu cbf cerebr autoregul ischem stroke event present review aim describ recent evid tcd util neurolog cardiolog set | D054092;D013345;D020301 | T047;T046;T019 |
36,218,210 | role differ echocardiograph modal assess microvascular function women ischemia obstruct coronari arteri review summar current knowledg echocardiograph modal use assess microvascular function left ventricular lv systol function women ischemia obstruct coronari arteri inoca although entir pathophysiolog background clinic entiti still remain elus primarili link microvascular dysfunct assess coronari flow veloc reserv subtl impair lv systol function women inoca difficult assess interpret wall motion abnorm lv longitudin function impair consid earli marker subclin systol dysfunct assess global longitudin strain quantif | D003331;D018487 | T023;T046 |
36,218,209 | multimod imag manag patient primari mitral regurgit advanc cardiac imag aci includ myocardi deform imag echocardiographi cardiac magnet reson overcom limit convent echocardiographi assess patient primari mitral regurgit mr enabl precis mr quantif reveal earli chang advanc irrevers remodel depress heart function occur aci permit thorough analysi mitral valvular anatomi mr mechan import plan guid percutan surgic procedur help identifi structur function chang coupl high arrhythmogen potenti especi occurr atrial fibril heart failur develop key question data provid aci improv current manag primari mr | D019560;D008944 | T047;T060 |
36,218,208 | role imag infect endocard infect endocard ie pose larg diagnost therapeut challeng earli diagnosi necessari posit outcom echocardiographi initi diagnost method possibl ie presenc tte tee use detect accur localis estim veget size also detect paravalvular spread infect certain situat need usag complementari method like cct nuclear techniqu articl outlin advantag limit certain diagnost method diagnosi ie | D017548;D004696 | T047;T060 |
36,218,207 | multimod imag approach patent foramen oval practic consider transient ischem attackstrok patent foramen oval present popul risk factor cryptogen stroke account stroke transient ischem attack via paradox embol narrat review focus multimod imag approach diagnosi periprocedur guidanc patent foramen oval emphasi use agit salin contrast medium echocardiographi start embryolog aspect therefor aim make concis complet present protocol use type evalu along multimod imag approach patent foramen oval practic consider transient ischem attackstrok | D019320;D054092;D002546;D020521 | T047;T019 |
36,218,206 | basic heart anatomi physiolog cardiologist perspect toward better understand left ventricular mechan systol diastol function comprehens understand cardiac structur function relationship essenti proper clinic cardiac imag review summar basic heart anatomi physiolog perspect heart imag focus myocardi mechan main issu analyz left ventricular lv architectur lv myocardi deform cardiac cycl lv diastol function basic paramet basic paramet lv deform use clinic practic lv function assess | D000072096;D018487 | T046;T097 |
36,218,205 | left atrial dysfunct major driver heart failur preserv eject fraction syndrom left atrial la dysfunct seem play central role pathophysiolog heart failur preserv eject fraction hfpef associ diseas sever poor outcom potenti impact manag identifi la myopathi help guid tailor therapi hfpef echocardiographi allow accur measur atrial size function la strain appear sensit measur intrins la myopathi sever therapi devic decompress left atrium test hfpef investig requir understand specif atrial effect statin mineralocorticoid receptor antagonist therapi | D006333;D019161 | T121;T047;T046;T109 |
36,218,204 | doubl outlet right ventricl adult anatom variabl surgic treatment late postop complic doubl outlet right ventricl dorv high complex congenit heart diseas chd entiti gain increas interest due rapid progress cardiac surgeri number patient oper congenit defect grow sinc follow decad activ transit cohort adult medicin howev divers initi anomali perform intervent make challeng manag patient particular import region special adult chd cardiolog still remain underdevelop review observ basic principl dorv nomenclatur main type oper possibl late complic articl focus adult patient offer illustr clinic practic | D006348;D004310 | T061;T047;T019 |
36,218,203 | differenti diagnosi cardiac tumor general consider echocardiograph approach cardiac tumor may primari either benign malign secondari malign first detect echocardiographi case cardiologist often challeng identif differenti diagnosi best therapeut approach malign tumor usual poor prognosi may signific improv appropri time therapi echocardiograph aspect benign malign cardiac tumor describ articl along clinic evalu may orient differenti diagnosi aid choos step use defin natur mass | D006338 | T191;T047 |
36,218,202 | peak treadmil exercis echocardiographi ischemia detect stress echocardiograph method exercis first choic patient abl exercis accord guidelin among exe modal treadmil exe acquisit imag peak exercis sever advantag includ high sensit prognost valu overal sensit exe around although figur peak imag treadmil despit guidelin mention method | D004452;D005080 | T060 |
36,218,201 | multimod imag cardiac amyloidosi state art review amyloidosi system diseas character deposit amyloid fibril various organ includ heart diagnosi cardiac amyloidosi ca requir high level clinic suspicion presenc clinic laboratori electrocardiograph red flag comprehens multimod imag evalu warrant includ echocardiographi magnet reson scintigraphi comput tomographi confirm diagnosi defin ca subtyp utmost import plan treatment strategi review use multimod imag evalu ca includ latest applic practic flow chart sum evid | D000682;D000686 | T047;T123;T116 |
36,218,199 | cardioren syndrom pathophysiolog key therapeut approach diagnos diseas cardioren syndrom clinic condit impact heart kidney one organ chronic acut impair lead chronic acut dysregul cardioren syndrom group five subcategori describ etiolog pathophysiolog durat pattern cardiac renal dysfunct classif reflect larg spectrum interrel dysfunct underlin bidirect natur heart kidney interact howev evid need appli earli find medic practic understand relationship two organ organ impair signific clinic implic relev therapi chronic acut condit epidemiolog definit classif pathophysiolog therapi outcom form cardioren syndrom examin review | D059347;D006333 | T047;T046 |
36,218,193 | sulfur dmso promot oxid coupl activ methylhetaren amin access amid element sulfur dmso coupl found effici promot oxid coupl activ methylhetaren amin yield amid simpl heat condit methylquinolin use methylhetaren compon format expect quinolinecarboxamid anilin could effici catalyz iron nickel cobalt salt method display good function group toler applic aromat heteroaromat aliphat amin substrat phenylacet acid dibenzyl disulfid benzylamin could act compet partner place methylhetaren | D000588;D000577 | T109 |
36,218,175 | qualit identif intervent prefer support men engag retent tb care south africa global south african specif men account tuberculosi tb case respect men increas risk access tb test treatment poor treatment outcom unfortun intervent exist address issu toward develop target patient center tb care support intervent use semistructur interview explor men social network composit tb test behavior disclosur treatment support clinic experi tb influenc daili live data analyz use themat approach guid network individu resourc model identifi mental tangibl resourc influenti prefer engag tb treatment men emphas desir peer peer support navig tb relat stigma unhealthi masculin norm men advoc awar event educ communiti challeng tb men strong suggest intervent deliv familiar locat men congreg sinc tb treatment support intervent includ prefer compon deliveri mode describ men studi improv men tb relat health outcom global tb communiti must identifi address men uniqu challeng design intervent | D008571;D014376 | T098;T047;T100 |
36,218,172 | emerg ser biosensor analysi cell extracellular vesicl cell deriv extracellular vesicl ev exosom contain uniqu molecular signatur could use biomark detect sever diseas cancer well monitor treatment respons reveal molecular signatur requir develop non invas ultrasensit tool enabl singl moleculecel level detect use small volum sampl low signal nois ratio background multiplex capabl surfac enhanc raman scatter ser address current limit studi cell ev two main mechan plasmon enhanc electr field call electromagnet mechan em chemic mechan cm review first highlight two ser mechan discuss nanomateri use develop ser biosensor base aforement mechan well combin two mechan order take advantag synerg effect electromagnet enhanc chemic enhanc review recent advanc design label aid label free ser biosensor colloid planar system investig surfac biomark cancer cell deriv ev final discuss perspect emerg ser biosensor futur biomed applic believ review articl thus appeal research field nanobiotechnolog includ materi scienc biosensor biomed field | D015374;D049329;D000067128 | T059;T026;T075;T073 |
36,218,171 | bf oet catalyz synthesi spirobi h benzopyran h chromen new bf oet catalyz approach develop construct spirobi h benzopyrancarboxyl react ethyl chloromethyl hydroxi h chromen carboxyl salicylaldehyd reaction proceed format c c c bond one pot structur assign compound c confirm singl crystal x ray analysi | D001578;D002264 | T109 |
36,218,163 | hfip promot halo carbocycl n tether aren alken substrat access halo x br cl function tetrahydroquinolin chroman core new method stereoselect metal addit oxid free friedel craft type halo carbocycl n tether aren olefin substrat report involv reaction suitabl electrophil halogen reagent nxsdcdmh hexafluoroisopropanol halo x br cl function tetrahydroquinolin chroman obtain excel yield high level diastereocontrol dr product success transform synthet use compound dihydroquinolin partial full azahelicen compound | D000475;D011804 | T109 |
36,218,160 | bio inspir self adapt nanocomposit array non antibiot antibacteri action cell prolifer pathogen bacteri infect poor nativ tissu integr two major issu encount biomateri implant devic extrem hard overcom within singl surfac especi without involv antibiot herein self adapt surfac transform non antibiot antibacteri action promot cell prolifer develop situ assembl bacteriostat diaminodipropylamin dadp dope zeolit imidazol framework zif bio inspir nanopillar initi nanocomposit surfac show impress antibacteri effect even sever bacteri infect due combin mechano bactericid activ nanopillar structur bacteriostat activ contribut ph respons releas dadp complet degrad zif layer refurbish nanopillar still physic ruptur bacteri membran also facilit mammalian cell prolifer due obvious differ cell size strike nanocomposit surfac total avoid usag antibiot erad potenti risk antimicrobi resist surfac exhibit excel histocompat lower inflammatori respons properti reveal vivo test type self adapt surfac may provid promis altern address intract implant associ requir antibiot free antibacteri activ nativ tissu integr high need | D053761;D017641 | T073;T197 |
36,218,159 | resili amongst ontario regist practic nurs long term care home covid ground theori studi studi aim understand person profession resili regist practic nurs work long term care ltc home ontario impact coronavirus pandem | D000086382;D009726 | T047;T097;T067 |
36,218,154 | increas ocular wall thick decreas globe volum children mucopolysaccharidosi type vi purpos lthough clinic ophthalmolog find report studi document magnet reson imag mri find mucopolysaccharidosi mps type vi aim studi determin ophthalmolog imag find mps type vi pediatr age group retrospect method brain mris patient mps type vi healthi children evalu independ two pediatr radiologist follow characterist globe volum ocular wall thick optic nerv sheath diamet orbit mean measur group compar use independ test agreement bias review assess intra class correl coeffici icc result total children girl boy age rang year mean age year includ studi statist analysi reveal smaller eyebal thicker ocular wall patient mps type vi p p respect howev statist signific differ term optic nerv sheath diamet two group p conclus patient mps type vi display reduc globe volum increas ocular wall thick compar healthi children therefor recommend ophthalmolog imag find might prove auxiliari tool diagnosi mps patient | D009087 | T047 |
36,218,153 | role f fdg petct detect recurr metastas renal cell carcinoma underus petct purpos aim studi compar f fluorodeoxyglucos positron emiss tomographi comput tomographi f fdg petct scan comput tomographi ct scan detect recurr metastasi renal cell carcinoma patient method retrospect studi includ patient octob april contrast enhanc ct petct scan compar correl histopatholog orand follow studi result seventi six patient male includ lesion includ primari renal recurr renal fossa lesion lymph node distant metastat lesion malign lesion ct detect lesion true posit twenti two fals negat lesion show abnorm fdg uptak ct scan posit predict valu ppv negat predict valu npv sensit specif accuraci respect lesion petct posit petct ppv npv sensit specif accuraci specif npv petct superior p conclus petct appear accur ct scan detect metastasi recurr renal cell carcinoma patient | D002292;D007680 | T191 |
36,218,152 | balloon occlud middl adren arteri embol percutan microwav ablat metastat adren tumor renal cell carcinoma renal cell carcinoma present local advanc metastat diseas patient thermal ablat may consid select patient singl site oligometastat diseas select patient describ singl session transarteri particl embol assist balloon occlus cathet microwav ablat larg hypervascular adren metastasi use cone beam ct fluoroscop xperguid needl guidanc | D000310;D002292;D017115;D007680 | T191;T061 |
36,218,151 | imag guid embol arterioven malform hand use ethylen vinyl alcohol copolym purpos studi aim evalu safeti outcom imag guid embol treat arterioven malform avm hand use ethylen vinyl alcohol copolym evoh method retrospect multicent cohort patient avm hand treat imageguid embolotherapi use evoh investig clinic histori symptomatolog imag find assess evalu clinic outcom symptom free partial relief pain improv pain clinic progress despit embol lesion devascular total near total substanti partial failur peri postprocedur complic rate major complic classifi accord cirs guidelin substratif analysi perform respect involv differ anatom compart inject volum embol agent result patient treat pain skin ulcer local bleed mean number embolotherapi patient plan surgic resect conduct embol clinic outcom median follow month reveal overal respons patient imag last follow reveal reduc vascular patient includ patient neartot devascular peri postprocedur complic occur respect includ major complic case requir previous unplan resect involv finger associ increas rate persist symptom compar group p signific differ embol agent volum inject complic rate found p conclus imag guid embol use evoh base liquid embol agent effect treat avm hand mid term | D001165;D004621 | T061;T019 |
36,218,150 | efficaci safeti splenic arteri embol intract ascit use amplatz vascular plug versus coil live donor liver transplant purpos intract ascit ia uncommon challeng complic liver transplant splenic arteri embol sae modul splenic arteri regul portal flow studi aim evalu efficaci safeti sae use amplatz vascular plug avp versus coil embol post live donor liver transplant ldlt ia method retrospect studi evalu consecut patient center receiv ldlt n march august inclus criteria sae splenomegali ia ldlt result total patient underw sae post ldlt ia eleven patient receiv avp embol age year rang year men women compar patient receiv coil embol age year rang year men women avp coil embol signific reduc portal vein hyperflow plug coil p decreas ascit volum plugcoil p benefit avp embol includ shorter procedur time p signific reduc splenic volum p increas liver volum p decreas spleenliv ratio p improv pancytopenia p due secondari hypersplen signific differ found two group length hospit stay complic splenic infarct pancreat sepsi conclus sae use avp coil embol provid effect safe method manag patient ia ldlt avp embol may effici coil embol provid effect reduct ascit volum advantag shorten procedur time improv hypersplen | D004621;D006971;D016031 | T061;T047 |
36,218,149 | key concept common pitfal best practic artifici intellig machin learn focus radiom artifici intellig ai machin learn ml increas use radiolog research deal larg complex imag data set nowaday ml tool becom easili access anyon low threshold access might lead inappropri usag misinterpret without clear intent therefor ensur methodolog rigor paramount import get closer real world clinic implement ai basic understand main concept must everi radiolog profession respect simplifi explan key concept along pitfal recommend would help general radiolog communiti develop improv ai mindset work twenti two key issu review within three categori pre model model post model first concept short defin issu relat common pitfal best practic provid specif issu includ paper valid scientif question unrepres sampl sampl size miss data qualiti refer standard batch effect reliabl featur featur scale multi collinear class imbal data target leakag high dimension data optim overfit general perform metric clinic util comparison convent statist clinic method interpret explain random transpar report share data | D001185;D011871 | T090;T091;T066;T073 |
36,218,148 | diagnost valu magnet reson imag featur microvascular invas hepatocellular carcinoma meta analysi purpos systemat review meta analysi convent enhanc magnet reson imag mri conduct evalu diagnost perform imag featur microvascular invas mvi predict hepatocellular carcinoma hcc method relev studi diagnos mvi hcc mri search medlin pubm embas cochran librari web scienc databas pool mean sensit specif calcul use random effect model correspond posit likelihood ratio plr negat likelihood ratio nlr pool diagnost odd ratio dor calcul summari receiv oper characterist sroc curv use summar overal diagnost accuraci diagnost perform evalu determin area curv auc regress analysi subgroup sensit analysi use explor potenti sourc heterogen result total studi compris hcc patient tumor ultim enrol sign presenc peritumor enhanc arteri phase peritumor hypointens hepatobiliari phase irregular non smooth margin rim like enhanc arteri phase pool sensit valu pool specif valu pool plr valu pool nlr valu pool dor valu valu auc sroc curv determin conclus convent mri featur predict mvi show poor diagnost perform hcc sign presenc peritumor enhanc arteri phase show moder diagnost accuraci | D006528;D008113 | T191 |
36,218,147 | speed sound index liver steatosi estim reliabl studi normal subject purpos non alcohol fatti liver diseas nafld widespread type chronic liver diseas western countri ultrasound us wide use nafld stage resona us system mindray bio medic electron co ltd includ imag optim speed ultrasound relat featur sound speed index ssi ssi appli region interest roi could potenti aid tissu character purpos studi evalu reliabl ssi various examin paramet normal subject method twenti normal subject examin two radiologist perform ssi measur liver differ roi depth size intraclass correl coeffici icc calcul measur intra inter observ variabl inter roi variabl result roi radiologist mean inter observ icc mean intraobserv icc mean ssi valu roi examin rang ms conclus result indic ssi lead reliabl measur normal subject independ roi size depend roi placement studi process nafld patient util refer method liver fat quantif either reliabl correl ssi perform investig relev ssi potenti biomark clinic practic liver steatosi grade | D065626 | T047 |
36,218,146 | ct clinic featur distinguish endophyt clear cell renal cell carcinoma urotheli carcinoma purpos aim character clinic multiphas comput tomographi ct featur distinguish endophyt clear cell renal cell carcinoma eccrcc endophyt renal urotheli carcinoma eruc method data patient men women eccrcc patient men women eruc retrospect assess mean patient age year year year year respect univari multivari logist regress analys perform determin independ predictor eccrcc construct predict model compris clinic ct characterist differenti diagnosi eccrcc eruc differenti diagnost perform assess use area receiv oper characterist curv auc result independ predictor eccrcc heterogen enhanc odd ratio p hematuria gross hematuria p microscop hematuria p infiltr growth pattern p auc predict model p sensit specif better diagnost perform heterogen enhanc auc p sensit specif hematuria auc p sensit specif infiltr growth pattern auc p sensit specif conclus independ predictor well predict model ct clinic characterist may assist differenti diagnosi eccrcc eruc provid use inform clinic decis make | D002292;D002295;D007680;D001749 | T191 |
36,218,141 | pulmonari embol menopaus hormon therapi popul base regist studi oral transderm menopaus hormon therapi mht increas risk venous thromboembol evid regard risk serious complic pulmonari embol pe aim investig risk pe women use mht depend administr rout type progestin treatment durat | D015914;D011655 | T061;T047;T046 |
36,218,140 | character escherichia coli pyridox phosphat homeostasi protein yggs role lysin residu plp bind protein stabil pyridox phosphat plp homeostasi protein plphp ubiquit member cog famili appar catalyt activ although actual cellular role protein unknown observ mutat plphp encod gene affect activ plp depend enzym b vitam amino acid level report detail character escherichia coli ortholog plphp yggs respect plp bind transfer properti stabil structur yggs bind plp tight abl slowli transfer model plp depend enzym serin hydroxymethyltransferas plp bind yggs elicit conformationalflex chang protein structur detect solut crystal serendipit discov ka variant yggs affect lysin residu bind plp activ site abl bind plp coval observ led us recogn number lysin residu locat entranc activ site replac lys plp bind role lysin form cluster charg residu affect protein stabil conform play import role plp bind possibl yggs function | D004926;D029968 | T007;T116 |
36,218,139 | synthesi core shell nanoparticl base interfaci energi transfer red emiss high sensit temperatur sens red convers luminesc emiss excit peak within tissu transpar window make ideal fluoresc label deep tissu penetr low background biolog imag work effici strategi propos realiz bright red convers luminesc base interfaci energi transfer iet luminesc center er tm sensit yb dope separ layer avoid deleteri cross relax iet process yb er enabl bright red photon convers nm excit via fine control manipul lanthanid ion concentr shell thick appropri employ fluoresc intens ratio techniqu optic thermomet base non thermal coupl energi level demonstr superior relat sensit k across whole temperatur region nayf er tm nayf yb strong red uc luminesc high sensit perform exhibit potenti applic field non contact temperatur sens | D053758;D028581 | T196;T073 |
36,218,136 | ultralight type transvagin mesh altern recurr sever posterior vagin prolaps studi aim analyz medium term outcom ultralight type mesh postmenopaus women recurr sever posterior vagin prolaps pvp | D014596;D056887 | T047;T190;T020 |
36,218,134 | assembl induc pdc enabl effici nuclear deliveri nucleic acid cancer stem like cell suppress nucleic acid therapi attract great attent divers clinic translat therapeut advantag renown oligonucleotid therapeut candid clinic stage shown outstand tumor suppress effect howev effici deliveri cell nucleus critic anticanc effect herein identifi multifunct peptid drug conjug pdc safe effici carrier achiev nuclear deliveri pdc consist cell penetr peptid rw hdac inhibitor warhead peptid c terminus fu peptid n terminus coassembl form nanospher pdc effici deliv nucleus sever type cancer cell moreov revers stem cancer stem like cell line signific due assembl induc accumul enhanc retent safe singl agent concentr pdc show unexpect synergi augment cancer cell suppress effici exemplifi downregul stem relat protein upregul apoptosi relat protein therefor work present power strategi nuclear deliveri nucleic acid drug leverag cancer suppress pdc assembl induc provid power combin regimen treat cancer stem like cell | D009696;D052157;D000970;D009369 | T121;T191;T109;T123;T114 |
36,218,133 | aie activ ir iii complex functionalis cation schiff base ligand synthesi photophys properti applic photodynam therapi photodynam therapi pdt promis cancer treatment method tradit small molecul photosensit pss suffer low intersystem cross isc abil aggreg caus quench acq advers affect lumin effici singlet oxygen yield pss aggreg state ir iii complex promis pss long excit state lifetim good photophys photochem properti larg stoke shift aggreg induc emiss aie characterist could reduc nonradi recombin improv isc abil excit state restrict intramolecular motion aggreg state accord two aie activ ir iii complex ir n ir n success design obtain base schiff base ligand experiment result show ir n ir n good photophys properti correspond nanoparticl nps good water solubl generat abil notabl ir n nps effici taken mous breast cancer cell cell good biocompat low dark toxic excel phototox work demonstr versatil strategi exploit effici transit metal pss cation ligand pdt | D010778 | T061 |
36,218,131 | genet variat adipoq gene serum adiponectin increas risk bladder cancer bladder cancer bc th common cancer worldwid genet studi estim herit bc risk adiponectin adipocytokin import role regul energi metabol recent evid suggest dysregul adiponectin level bc tissu serum level adiponectin influenc singl nucleotid polymorph snps adipoq gene howev limit evid avail regard associ adiponectin serum level snps adipoq bc risk studi aim assess whether adiponectin serum level snps adipoq may modifi bc risk case control studi bc patient recruit along control studi subject genotyp variat adipoq snps name rs rs rs rs adiponectin level measur serum studi subject analysi show g allel gg genotyp rs signific frequent bc patient compar control group p valu moreov two adipoq haplotyp contain g allel associ increas bc risk p valu multivari analysi show increas serum adiponectin smoke age signific predictor bc p valu data support use serum adiponectin g allel rs snp adipoq potenti biomark andor target bc valid find studi larger popul various ethnic andor genet background requir investig function role adiponectin bc also provid better understand potenti target adiponectin bc treatment | D052242;D001749 | T191;T123;T116 |
36,218,130 | photodynam therapi breast cancer treatment breast cancer serious public problem modern societi photodynam therapi pdt increas use modern medicin current pdt innov method treat breast cancer irrevers damag neoplast tissu associ use physicochem process generat cytotox reactiv oxygen speci singlet oxygen lead tumor cell death time valuabl inform extract breast cancer cell photogener major factor respons cell necrosi pdt react rapid intracellular organ substanc use photodynam therapi tissu vitro creat condit test various type solut implement vivo treatment articl review recent advanc pdt treatment breast cancer pdt novel cancer diagnost cancer treatment therapi therefor understand possibl generat toxic form necessari knowledg gain basic pdt vitro use biomed applic vivo current literatur mention pdt treatment cancer locat deep within human bodi therefor develop agent use deliv deep cancer tissu new challeng effici impact disciplin review cover literatur | D001943;D010778 | T191;T061 |
36,218,129 | effect estradiol releas shape memori terpolym rod sciatic nerv regener injuri repair chitosan nerv conduit femal rat aim studi assess estradiol e influenc sciatic nerv regener injuri follow repair chitosan conduit ovariectom femal rat studi perform group n rat ovchit excis fragment sciatic nerv chitosan conduit implant ovchit group addit chitosan conduit shape memori terpolym rod base poli l lactid co glycolid co trimethylen carbon releas estradiol week implant mean number regener axon mean fiber area signific greater estradiol treat anim group infiltr leukocyt diminish presenc estradiol receptor alpha beta motoneuron spinal cord discov may indic locat estradiol affect regener injur nerv estradiol releas terpolym rod week could enhanc extent sciatic nerv regener injuri diminish inflammatori reaction futur estradiol entrap terpolym rod could use repair injur peripher nerv need studi | D048271 | T121;T109 |
36,218,128 | sar cov vaccin associ venous sinus thrombosi three patient increas evid vaccin sever acquir respiratori syndrom coronavirus type sar cov virus follow venous sinus thrombosi vst report three patient develop vst short sar cov vaccin | D000086382;D000086663;D012851;D014765 | T047;T121;T200;T129;T067 |
36,218,125 | extracardiac fontan complet kawashima procedur custom made bifurc graft patient year old girl underw previous kawashima procedur left side bidirect cavopulmonari anastomosi stage palliat function singl ventricl cardiac defect consist unbalanc right domin complet atrioventricular septal defect doubl outlet right ventricl also heterotaxi syndrom left isomer polysplenia interrupt inferior vena cava azyg continu right side superior vena cava nativ main pulmonari arteri left continu branch pulmonari arteri develop sinus node dysfunct dilat ascend aorta progress cyanosi proceed complet fontan use bifurc graft hepat vein pulmonari arteri confluenc replac dilat ascend aorta disconnect nativ main pulmonari arteri excis pulmonari valv cusp placement dual chamber epicardi pacemak | D018729;D006330;D006343;D054079 | T061;T042;T190;T019 |
36,218,124 | mediat role socioeconom status relationship pregnanc histori later life cognit associ pregnanc later life cognit well understood examin whether full term incomplet pregnanc associ cognit sampl postmenopaus women whether socioeconom status ses factor mediat relationship | D003072;D000544 | T047;T048 |
36,218,122 | two novel zinc base mof luminesc sensor detect phenylglyoxyl acid automobil exhaust gase plastic pollut smoke harm substanc caus serious harm human be environ styren common airborn toxin enter human bodi breath skin discharg form phenylglyoxyl acid pga therefor specif sensit trace detect pga particular import two zinc base metal organ framework zn l dmf h dmf h n zn l dmf h dmf n l bis carboxylphenyl amino terephthal acid l bis carboxyphenyl amino terephthal acid report respect present structur simplifi c net topolog worth mention two differ kind zn sbus connect node structur besid compar materi detect pga exhibit relat low detect limit lod water urin lod water urin rang mm rang mm respect addit sensor excel anti interfer abil high stabil rapid respons easili distinguish differ concentr pga nake eye develop paper probe suitabl practic sens applic portabl detect pga urin | D049449;D015032 | T121;T196;T123;T070 |
36,218,121 | self cascad nanoenzym cupric oxid nanoparticl cuo nps induc situ catalysi format polyelectrolyt templat synthesi near infrar fluoresc silver nanoclust applic glutathion detect bioimag work near infrar fluoresc silver nanoclust ag ncs prepar base situ form poli methacryl acid pmaa templat stabil synthes methacryl acid maa hydroxyl radic oh generat cascad nanoenzym reaction cupric oxid nanoparticl cuo nps cuo nps possess intrins glutathion like gpx like peroxidas like pod like activ catalyz glutathion gsh produc hydrogen peroxid h transform oh fluoresc intens ag ncs decreas addit gsh sh easili anchor surfac result pmaa leav ag ncs coeffect gsh pmaa result aggreg form larger ag nps good linear relationship fluoresc quench rate gsh concentr found rang detect limit nm ag ncs appli detect gsh serum well bioimag endogen exogen gsh cell high sensit moreov normal cancer cell distinguish bioimag differ gsh level new method prepar biocompat nanoprob base nanozym tandem catalysi situ form templat avoid direct usag polym protein templat hinder prepar separ provid reliabl approach synthesi biosens bioimag nanoclust | D012834;D053768 | T196;T073 |
36,218,119 | eeg abnorm indic genet determin epilepsi genet acquir factor contribut epileptogenesi epilepsi syndrom patient comprehens evalu compon etiolog essenti everi patient review author enumer eeg abnorm indic genet determin epilepsi author briefli describ general spike wave paroxysm focal spike sharp wave photosensit hz theta rhythm hz occipit intermitt rhythmic delta activ phi rhythm general monomorph alpha eeg background activ abnorm author review prior knowledg add recent research result neurophysiolog mean abnorm age distribut relationship epilepsi role eeg pattern epileptogenesi clinic present prognosi individu patient main aspect descript discuss eeg abnorm may shape typic syndrom specif phenotyp forecast sever diseas difficulti treatment pharmacoresist modifi syndrom specif general prognosi syndrom relationship epilepsi herit data eeg abnorm help estim risk epilepsi offspr epilepsi syndrom taxonom diagnost categori might enrich neurobiolog mean herit relat | D004827;D000073376 | T047;T033 |
36,218,118 | covid chronic pain onlin survey domest popul problem caus covid epidem worst impact chronic patient popul peopl chronic pain one vulner group due stress disrupt daili routin famili problem ill difficulti hospit care therefor essenti assess situat mental well group aim survey assess chronic pain patient covid pandem address psycholog background factor might affect pain symptom depress emot regul alexithymia well health literaci social support | D000086382;D059350 | T047;T184;T067 |
36,218,117 | adolesc sleep qualiti context internet use background purpos present studi continu previous research aim assess sleep qualiti adolesc light internet use | D007319 | T047;T184;T048 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.