PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,639,250 | use intraor scanner full dental arch could differ strategi overlap softwar affect accuraci use digit devic strong influenc dental rehabilit workflow singl crown rehabilit full arch prosthet treatment | D017076;D021621 | T062;T066;T073;T060 |
34,639,249 | valid generat act scale chines version gas c among middl age older adult grandpar mainland china current studi examin psychometr properti item generat act scale chines version gas c among middl age older adult grandpar mainland china total grandpar mean age year femal children kindergarten recruit use multistag cluster... | D000066502 | T099 |
34,639,248 | new enzian score repres stage system improv mri structur report structur report system endometriot diseas gain central role diagnost imag aim evalu applic feasibl recent enzian score assess mri total patient suspect tubo ovariandeep endometriosi retrospect includ studi accord follow criteria avail mr examin histopathol... | D004715;D010535 | T061;T191;T047;T060 |
34,639,247 | combin modifi mitchel osteotomi shorten obliqu osteotomi patient rheumatoid arthriti analysi chang plantar pressur distribut present studi aim evalu chang plantar pressur distribut joint preserv surgeri rheumatoid forefoot deform retrospect studi perform feet patient rheumatoid arthriti ra underw follow surgic combin m... | D001172;D006215 | T190;T047 |
34,639,246 | czech slovak member religi institut health comparison general popul studi examin general health consecr person cp czech republ cz slovakia sk compar control sampl czech popul sampl cp particip age sd femal czech slovak compar two control sampl one nation repres compar cp general popul measur frequenc recent health comp... | D011634;D012067 | T091;T078 |
34,639,245 | health literaci level among italian student monitor promot school health literaci identifi import determin health particular adolesc howev effort need monitor construct provid input polici develop studi aim assess valid reliabl italian version health literaci school age children hlsac b identifi health literaci level a... | D057220 | T041 |
34,639,244 | onset menstruat social network site use adolesc girl mediat role bodi mass index evid suggest girl spend much time social network site sns often boy propos may sex base differ need approach social posit adolesc girl also uniqu develop physiolog start menstruat base prior research hypothes onset menstruat drive physiolo... | D008572;D008598 | T040 |
34,639,243 | uterin adenomyosi diseas pathogenesi new medic approach use gnrh antagonist uterin adenomyosi common chronic disord frequent encount reproduct age women caus heavi menstrual bleed intens pelvic pain infertil despit high preval etiopathogenesi yet fulli understood current specif drug treat diseas number dysregul mechan ... | D062788;D014591 | T047 |
34,639,242 | pharmacist knowledg factor associ dementia z dementia knowledg list dementia neurodegen diseas cure begin year diagnosi key prioriti patient dementia identif earli modifi factor slow progress diseas communiti pharmaci suitabl point cognit impair screen proxim patient therefor continu train profession work pharmaci dire... | D003157;D003704;D019636 | T058;T048;T047 |
34,639,241 | irrat belief covid scope review sinc emerg recent coronavirus diseas covid spread pandem parallel spread fals mislead inform known infodem covid infodem induc distrust scientif communiti govern institut popul confid crisi led harm health behaviour also impact mental health aim studi provid scope review scientif literat... | D000086382 | T047;T067 |
34,639,239 | exosom brain metastas review role potenti applic brain metastas bm frequent complic patient advanc stage cancer associ impair neurolog function qualiti life prognosi surviv bm treatment consist combin avail cancer therapi surgeri radiotherapi chemotherapi immunotherapi target therapi even cancer patient bm still link p... | D002450;D059016 | T043;T070 |
34,639,237 | greeningdb databas host pathogen protein protein interact annot featur bacteria caus huanglongb hlb diseas citrus genus compris import common cultiv fruit plant within last decad citrus green diseas also known huanglongb hlb emerg biggest threat citrus industri diseas cure yet thus mani effort made find solut devast co... | D016208;D054884;D060066 | T040;T170;T169 |
34,639,233 | sphingosin phosphat lyas regul sensit pancreat beta cell lipotox elev level free fatti acid ffas relat pancreat beta cell failur type diabet tdm though under mechan yet fulli understood ffas shown dysregul format bioactiv sphingolipid ceramid sphingosin phosphat sp beta cell aim studi analyz role sphingosin phosphat ly... | D018384 | T049 |
34,639,232 | salt stress promot abscis acid accumul affect cell prolifer expans primari root rice primari root basic compon root system play key role earli seedl growth rice growth easili affect environment cue salt stress abscis acid aba play essenti role root develop molecular mechan under aba regul root growth respons salt stres... | D049109;D018506;D000077323 | T043;T039;T040;T045 |
34,639,231 | survey autoencod algorithm pave diagnosi rare diseas rare diseas rds concern broad rang disord result various origin long time scientif communiti unawar rds impress progress alreadi made certain rds howev due lack suffici knowledg mani patient diagnos nowaday advanc high throughput sequenc technolog whole genom sequenc... | D000465;D000069550;D016571 | T170;T066 |
34,639,228 | angiogen effect crosstalk adipos deriv mesenchym stemstrom cell extracellular vesicl endotheli cell adipos deriv mesenchym stemstrom cell asc adult stem cell popul abl self renew differenti numer cell lineag asc provid promis futur therapeut angiogenesi due abil promot blood vessel format specif abil differenti endothe... | D002450;D002454;D018919 | T043;T039 |
34,639,227 | complex transposon insert novel caus pomp diseas pomp diseas omim autosom recess lysosom storag disord caus mutat gaa gene accord public mutat databas pathogen variant describ gaa none associ mobil genet element articl report novel molecular genet caus pomp diseas could hard detect use routin molecular genet analysi wh... | D016254 | T049;T063;T045 |
34,639,226 | actin cytoskelet dynam singl cell wound repair plasma membran protect eukaryot cell surround essenti cell viabil thus crucial membran disrupt repair quick prevent immedi dyshomeostasi cell death accord cell develop effici repair mechan rapid reseal ruptur reestablish membran integr cortic actin cytoskeleton play instru... | D002468;D014945 | T043;T040 |
34,639,224 | cheonggukjang specif compon diphenyl propanon novel ppar dual agonist vitro silico studi cheonggukjang tradit ferment soybean past most consum korea howev biolog activ cheonggukjang specif compound studi thus aim discov novel dual agonist ppar dietari sourc cheonggukjang specif volatil compound explor potenti role ppar... | D003198;D062105 | T170;T066;T063 |
34,639,222 | crossroad cancer p induc cell fate decis secur genom integr p known critic tumor suppressor often refer guardian genom year discoveri still struggl understand molecular detail transcript factor prevent oncogenesi leverag current knowledg function improv cancer treatment multipl cue includ dna damag mitot error lead sta... | D017209;D059447;D004249;D005786 | T049;T116;T045;T123;T043 |
34,639,221 | agroinfiltr mediat scalabl transient gene express genom edit crop plant agrobacterium mediat transform one common use genet transform method involv transfer foreign gene target plant agroinfiltr agrobacterium base transient approach breakthrough discoveri crisprca hold trend statur perform target effici genom edit ge p... | D064113;D018745 | T040;T028 |
34,639,218 | healthi tissu damag follow cancer ion therapi radiobiolog databas predict lymphocyt chromosom aberr base bianca biophys model chromosom aberr wide consid among best biomark radiat health risk due relationship late cancer incid particular aberr peripher blood lymphocyt pbl regard indic hematolog toxic major limit factor... | D016923;D009010;D012062 | T043;T081 |
34,639,216 | differ glycolysi mitochondri respir cytotrophoblast syncytiotrophoblast vitro evid sexual dimorph placenta prolif cytotrophoblast cell fuse termin differenti syncytiotrophoblast layer undertak sever energi intens function includ nutrient uptak transfer hormon synthesi use seahors glycolyt mitochondri stress test tropho... | D006019;D012727 | T044;T032 |
34,639,214 | lef enhanc progress colon adenocarcinoma via remodel cell motil associ structur lymphoid enhanc bind factor lef key transcript factor mediat wnt signal pathway lef regul close associ tumor malign usual upregul cancer includ colon adenocarcinoma under molecular mechan lef regul colon adenocarcinoma progress remain unkno... | D002465;D015972 | T043;T045 |
34,639,212 | lung microbiom health diseas healthi human lung tradit consid steril organ howev cultur independ molecular techniqu report larg number microb coexist lung airway lung harbor divers microbi composit undetect previous approach mani studi found signific differ microbi composit health respiratori diseas lung microbiom like... | D054884;D064307 | T040;T032;T001;T028 |
34,639,211 | calmodulin ca depend interactor fto dioxygenas fto n methyladenosin demethylas remov methyl group nucleic acid sever studi indic creation fto complex protein look regulatori protein recogn part fto dioxygenas region calmodulin cam target databas found fto c domain potenti bind cam prove find experiment interact ca depe... | D020013;D054730 | T043;T116;T082;T123 |
34,639,209 | cryopreserv gamet embryo molecular chang process freez cell tissu deposit liquid nitrogen c call cryopreserv sub zero temperatur physiolog condit cell water ice crystal repres main problem sinc induc cell death princip larg cell like oocyt meiotic spindl degener process signific cryopreserv repres option fertil preserv... | D044127 | T045 |
34,639,208 | loop around heme pocket critic role function stabil bs dyp bacillus subtili bacillus subtili nbsp bs dyp belong class dye decolor peroxidas dyp famili enzym interest biocatalyst due high redox potenti broad substrat spectrum thermost work report optim bs dyp use direct evolut improv oxid dimethoxyphenol model lignin de... | D009154 | T045 |
34,639,206 | diffus axon injuri clinic prognost factor molecular experiment model impact trauma relat oxid stress extens review concern mileston advanc traumat brain injuri tbi condit burden extrem high rate morbid mortal result overal disabl rate high affect individu therefor import identifi clinic prognost factor diffus axon inju... | D018384 | T049 |
34,639,205 | comprehens analysi five phyllostachi eduli squa like gene potenti function flower develop bamboo one import non timber forest resourc worldwid consider econom valu uniqu flower characterist long juvenil phase bamboo unpredict flower time limit breed genet improv serious affect product applic bamboo forest member squa l... | D018507;D018506 | T045 |
34,639,204 | research progress mitochondri mechan nlrp inflammasom activ exercis regul nlrp inflammasom nlrp import pattern recognit receptor innat immun system activ induc larg number pro inflammatori cytokin il il involv develop various diseas recent year suggest mitochondria platform nlrp inflammasom activ addit exercis consid i... | D015444 | T061;T056 |
34,639,203 | stem cell macrophag role skelet muscl regen medicin sever muscl injuri skelet muscl tissu structur function repair involv sever cell type muscl stem cell innat immun respons howev exact mechan behind muscl tissu regener homeostasi plastic still investig discoveri pathway cell type involv muscl repair open way novel the... | D044968 | T091 |
34,639,202 | ion deep subsurfac earth mar ici moon effect combin temperatur pressur trna ligand bind interact ligand nucleic acid central numer reaction biolog cell reaction affect harsh environment condit low temperatur high pressur high concentr destruct ion still larg unknown elucid ion role shape habit extraterrestri environ de... | D011312;D013696 | T081;T067 |
34,639,201 | arsr transcript regul facilit brucella sp surviv via regul self outer membran protein arsenic acid resist arsr famili transcript regul wide distribut microorgan includ facult intracellular pathogen brucella spp arsr protein implic numer biolog process howev specif role arsr famili member brucella remain obscur show ars... | D015964;D014774 | T032;T038;T045 |
34,639,200 | system administr recombin irisin acceler fractur heal mice date pharmacolog strategi design acceler bone fractur heal lack subject week old cbl male mice close transvers mid diaphys tibial fractur treat intraperiton inject vehicl r irisin gkgweek immedi follow fractur day day histolog analysi cartilagin callus day show... | D017102;D010012 | T042 |
34,639,199 | oxytocin food intak control neural behavior signal mechan neuropeptid oxytocin produc paraventricular hypothalam nucleus supraopt nucleus hypothalamus addit extens studi influenc social behavior reproduct function central oxytocin signal potent reduc food intak human anim model potenti therapeut use obes treatment revi... | D012919 | T054 |
34,639,198 | silico analysi fatti acid desaturas structur camelina sativa function evalu csafad csafad seed oil format seed morpholog fatti acid desaturas add second bond singl bond carbon atom fatti acid chain result unsatur bond two carbon classifi solubl membran bound desaturas accord structur subcellular locat function ortholog... | D019143;D018506 | T038;T045 |
34,639,193 | proton pump non pump termin respiratori oxidas activ site intermedi molecular machin deriv termin respiratori oxidas high effici molecular machin import bioenerget membran enzym transform energi chemic bond releas transfer electron along respiratori chain eukaryot prokaryot cytochrom quinol molecular oxygen transmembra... | D011522 | T196 |
34,639,192 | saussurea involucrata snow lotus ice ice orthologu involv regul cold stress toler transgen arabidopsi environment stress cold stress limit plant growth geograph distribut agricultur product cbfdreb crt bind factor dre bind protein regul toler coldfreez stress across plant speci ice induc cbf express regard upstream ind... | D058639;D018506 | T040;T045 |
34,639,191 | host viral interact pathogenesi ulcer coliti ulcer coliti character relaps remit colon mucos inflamm earli stage viral infect innat immun defens activ lead rapid releas cytokin subsequ initi downstream respons includ inflamm previous intestin virus thought either detriment neutral host howev persist virus may role resi... | D000076662 | T070 |
34,639,189 | transcriptom wide analysi reveal role extracellular matrix integrin receptor gene otic neurosensori differenti human ipsc analyz transcriptom data otic sensori cell differenti human induc pluripot stem cell hipsc previous describ method gain new insight earli human otic neurosensori lineag identifi gene biolog network ... | D002454;D059467 | T043;T086;T081 |
34,639,184 | gpnmb extracellular fragment protect melanocyt oxid stress inhibit akt phosphoryl independ cd glycoprotein non metastat melanoma protein b gpnmb type transmembran glycoprotein play import role cancer metastasi osteoblast differenti skin epidermi gpnmb main express melanocyt play critic role melanosom format previous st... | D018384 | T049 |
34,639,182 | skin barrier dysregul psoriasi skin barrier broad compos two element physic barrier most localis epidermi immun barrier localis dermi epidermi two system interact cooper maintain skin homeostasi overal human health howev dysregul sever skin diseas may aris psoriasi one preval skin diseas associ disrupt barrier function... | D002463 | T043 |
34,639,181 | empagliflozin relax resist mesenter arteri stimul multipl smooth muscl cell voltag gate k k v channel antidiabet drug empagliflozin report produc rang cardiovascular effect includ reduct system blood pressur howev whether empagliflozin direct modul contractil resist size mesenter arteri remain unclear sought investig e... | D014664 | T042 |
34,639,180 | role non canon wnt signal pathway bone biolog wnt signal pathway one central signal pathway bone develop homeostasi regul bone miner densiti consist numer wnt ligand receptor co receptor ensur tight spatiotempor regul wnt signal pathway activ thus tight regul bone tissu homeostasi enabl mainten optim miner densiti tiss... | D002454;D010012;D060449 | T043;T044;T042 |
34,639,179 | process bypass site specif dna adduct cytotox platinum acridinylthiourea conjug polymeras involv dna repair biochem thermodynam aspect dna depend dna rna polymeras import modul biolog function replic transcript recombin repair work perform cell free media studi abil select dna polymeras overcom monofunct adduct cytotox... | D004249;D004260 | T049;T045 |
34,639,178 | sar cov virus host interact current avail structur implic variant emerg infect immun respons coronavirus diseas covid infect associ unpreced worldwid pandem caus sever acut respiratori syndrom coronavirus sar cov led million infect peopl million death worldwid sar cov cell infect initi dens glycosyl spike protein fusio... | D054884 | T040 |
34,639,177 | insight cadmium induc carcinogenesi vitro studi use chtcl cell multifacet role mitochondria paper report metabol character two foci f f obtain end cell transform assay cta perform treat chtcl mous embryo fibroblast cdcl h elucid cadmium action mechan use improv vitro cta yield insight carcinogenesi metabol two foci inv... | D006019;D010085 | T044 |
34,639,175 | identif rare lrp variant cohort male impair bone mass osteoporosi common bone diseas character reduc bone mass increas bone fragil genet contribut one main caus primari osteoporosi therefor gender affect skelet disord nonetheless osteoporosi men receiv littl attent thus underestim undertr aim studi identifi novel genet... | D015519;D009154 | T081;T045;T201 |
34,639,174 | tissu sampl homogen sub microlit scale nanosecond infrar laser nirl mass spectrometr proteom recent shown ultrashort puls infrar ir laser oper wavelength oh vibrat stretch band water high effici sampl homogen biolog tissu studi util tunabl nanosecond infrar laser nirl tissu sampl homogen subsequ liquid chromatographi t... | D007259;D007834 | T070;T074;T073 |
34,639,173 | ch type zinc finger protein millettia pinnata mpzfp enhanc salt toler transgen arabidopsi ch zinc finger protein zfps play import role plant develop respons abiot stress studi extens howev studi zfps mangrov mangrov associ repres uniqu plant communiti robust stress toler mpzfp high induc salt stress mangrov associ mill... | D000070580;D018506;D055049 | T040;T087;T045 |
34,639,172 | feed rhythm induc hypothalam agouti relat protein elev via glucocorticoid lead insulin resist skelet muscl circadian phase shift peripher clock induc chang feed rhythm often result insulin resist howev whether hypothalam control system energi metabol involv feed rhythm relat develop insulin resist unknown show physiolo... | D004734;D005247;D007333 | T040;T039;T046;T055 |
34,639,171 | chang stress mediat marker human cardiomyocyt cell line hyperglycemia diabet major risk factor cardiovascular diseas especi cardiomyopathi condit smooth muscl heart becom thick rigid affect function cardiomyocyt contractil cell heart uncontrol elev glucos level time result oxid stress could lead inflamm alter epigenet ... | D044127;D013312 | T121;T045;T039;T046;T032;T040 |
34,639,170 | immunogenet molecular microbiot determin eosinophil esophag clinic practic new perspect old diseas eosinophil oesophag eoe chronic allerg diseas associ lymphocyt respons induc esophag eosinophil infiltr esophagus inflamm tissu fibrosi respons main clinic symptom food impact dysphagia etiopathogenesi multifactori genet ... | D007125 | T091 |
34,639,169 | adp ribosyl post translat modif protein use inhibitor cancer control among post translat modif protein adp ribosyl studi fifti year larg set function includ dna repair transcript cell signal assign post translat modif ptm review present updat function larg set enzym writer reader recruit modifi target eras revers modif... | D000074744;D011499 | T044 |
34,639,166 | genom wide analysi udp glycosyltransferas famili reveal role coumarin biosynthesi abiot stress melilotus albus coumarin natur product abund melilotus albus confer featur respons abiot stress main present glycoconjug ugt udp glycosyltransferas respons glycosyl modif coumarin howev inform regard relationship coumarin bio... | D018745;D013312 | T121;T039;T046;T032;T028;T040 |
34,639,163 | role gpr function blood vasculatur sinc first promin descript orphan g protein coupl receptor gpr lymphocyt co receptor human immunodefici virus hiv type first report gpr trigger cytoprotect effect vascular endotheli cell recombin human thrombomodulin sever decad pass gpr recent deorphan new find gpr review summar cons... | D019610;D018919 | T039 |
34,639,162 | transcriptom analys identifi potenti key microrna target gene contribut ovarian reserv femal endocrinolog symptom prematur ovarian ineffici poi caus diminish ovarian reserv chemotherapi etiolog poi remain unknown lead infertil acceler search master regul gene molecul contribut enhanc silenc impact regulatori microrna m... | D015972;D053263;D065851;D059467 | T044;T045;T042;T081;T086 |
34,639,161 | amyloid process age sb transgen mice sex depend background calcium bind protein sb involv neuroregener also associ neurodegener contrast effect may result concentr durat exposur investig effect long term increas sb level amyloid process one year old transgen tg mice copi murin sb gene specif consider sex specif brain r... | D011499 | T044 |
34,639,160 | inflamm oxid stress diabet kidney diseas target sglt inhibitor glp receptor agonist incid type diabet td increas worldwid diabet kidney diseas dkd remain one lead long term complic td sever line evid indic glucos lower agent prevent onset progress dkd earli stage limit efficaci later stage dkd howev sodium glucos cotra... | D018384 | T049 |
34,639,159 | predict model agonist antagonist molecular initi event toxic pathway use improv deep learn base quantit structur activ relationship system silico approach studi intens assess toxicolog risk various chemic compound altern tradit vivo anim test among approach quantit structur activ relationship qsar analysi advantag abl ... | D000465;D000077321;D015233;D021281 | T170;T066;T081 |
34,639,158 | metabolom comparison drug resist drug suscept pseudomona aeruginosa strain intra extracellular analysi pseudomona aeruginosa common human pathogen belong eskap group multidrug resist bacteria consider problem treat patient may lead increas morbid mortal rate natur resist organ caus product specif enzym biofilm format a... | D024901 | T032 |
34,639,157 | novel gucaa variant associ cone dystrophi alter cgmp signal photoreceptor strong interact hyperactiv retin guanyl cyclas guanyl cyclas activ protein gcap encod gucaa gene neuron calcium sensor protein involv shape photorespons kinet cone rod gcap acceler slow cgmp synthesi oper retin guanyl cyclas gc base light depend ... | D009154 | T045 |
34,639,156 | neutrophil pathway inflamm character blood transcriptom signatur patient psoriasi cardiovascular diseas patient psoriasi increas risk atherosclerot cardiovascular diseas cvd molecular mechan behind connect fulli understood involv neutrophil drawn attent share inflammatori factor | D059467 | T086;T081 |
34,639,154 | znf enhanc mll af depend hematopoiet stem cell transform acut myeloid leukemia alter gene express landscap leukemia deriv mll af rearrang reli dysfunct transcript network znf transcript co factor implic control hematopoiesi propos sustain leukem transform collabor oncogen demonstr znf mrna level correl specif genet abe... | D015972 | T045 |
34,639,153 | culturom approach expand diagnost accuraci sexual transmit infect sexual transmit infect stis major health concern clinic manifest acknowledg caus sever reproduct impair research infecti diseas center around known major pathogen decad howev begun understand microbiota femal genit tract particular import diseas initi in... | D064307 | T032;T001;T028 |
34,639,151 | possibl mechan graphen oxid enhanc thermost psicos epimeras reveal molecular dynam simul thermal stabil limit factor effect applic psicos epimeras dpeas enzym recent report thermal stabil dpeas improv immobil enzym graphen oxid go nanoparticl howev detail mechan known studi investig interact detail go dpeas perform mol... | D006358 | T070 |
34,639,150 | therapeut potenti main method obtain selenium nanoparticl review present latest data import selenium nanoparticl human health use medicin main known method product various method recent year multifacet studi nanoscal complex medicin includ selenium nanoparticl becom import view number posit featur make possibl creat ne... | D050997 | T090 |
34,639,149 | fusarium graminearum fgsg xylanas enhanc plant immun increas resist bacteri fungal pathogen fungal enzym degrad plant cell wall xylanas activ plant immun respons fusarium graminearum fgsg xylanas previous shown elicit necrosi hydrogen peroxid accumul wheat investig abil induc diseas resist aim transient constitut expre... | D057865 | T039 |
34,639,148 | differenti marker express keratinocyt stem cell progeni generat singl coloni stem keratinocyt stem cell kscs determin gene express pattern kscs crucial maintain epiderm homeostasi wound repair wide use candid therapeut applic although sever studi report posit identifi uniqu biomark kscs remain elus aim identifi potenti... | D005786 | T045 |
34,639,147 | potato juic starch industri wast cost effect medium biosynthesi bacteri cellulos work verifi possibl valor major wast product potato starch industri potato tuber juic pj obtain cost effect ecolog friend microbiolog medium yield bacteri cellulos bc properti equival convent commerci hestrin schramm medium bc yield pj med... | D003362 | T057;T081 |
34,639,146 | residu helic activ site histidin phosphocarri hpr modul bind affin natur partner phosphoenolpyruv depend phosphotransferas system pts modul preferenti use sugar bacteria first protein cascad common organ ei hpr activ site hpr involv histidin locat immedi begin first helix regul sigma rsd protein also bind hpr region hp... | D009154 | T045 |
34,639,145 | cnpase cyclic nucleotid phosphodiesteras therapeut target attenu cardiac hypertrophi enhanc mitochondri energi product heart failur end stage cardiovascular diseas year surviv rate insuffici mitochondri energi product meet myocardi demand hallmark heart failur mitochondri compon involv regul atp product remain fulli el... | D064113;D004195;D004734 | T040;T039;T050 |
34,639,144 | parkinson diseas protein park relat abil mammalian sperm undergo vitro capacit parkinson diseas protein park multifunct protein known involv regul sperm motil mitochondri function oxid stress respons mammalian sperm ros generat need activ downstream signal pathway requir sperm undergo capacit oxid stress detriment effe... | D020101;D005089;D053078;D013075;D013081 | T043 |
34,639,142 | evalu molecular dock softwar small molecul bind g quadruplex dna g quadruplex four strand nucleic acid secondari structur biolog signific emerg attract drug target g form myc promot mycg one studi small molecul target model system parallel structur preval promot dna gs rna gs molecular dock becom essenti tool structur ... | D054856;D062105;D012984 | T073;T170;T086;T063;T090 |
34,639,141 | ubiquitin cell activ checkpoint inhibit new avenu target cancer immunotherapi advent cell base immunotherapi remark transform cancer patient treatment despit success current approv immunotherapeut protocol still encount limit caus toxic give dispar patient outcom thus deeper understand molecular mechan cell activ inhib... | D054875 | T044 |
34,639,139 | reactiv oxygen speci free radic oxid stress skin diseas oxygen atmospher crucial compon life sustain aerob respir human approxim oxygen consum energi ultim becom water howev remain produc metabolit call activ oxygen reactiv oxygen speci ros extrem reactiv skin largest organ human bodi expos air pollut includ diesel exh... | D018384 | T049 |
34,639,138 | oligomer structur transit hspb chines hamster hspb mammalian shsp ubiquit express almost tissu involv regul mani vital function although recent crystal structur human hspb show monom form oligomer complex human hspb spheric configur molecular architectur hspb still controversi studi examin oligomer structur chang cghsp... | D011487;D055503 | T082;T067 |
34,639,137 | ryanodin receptor sensor intracellular environ muscl ryanodin receptor ryr ca releas channel sarcoplasm reticulum skelet cardiac muscl play key role excit contract coupl activ ryr regul chang level mani intracellular factor dival cation ca mg nucleotid associ protein reactiv oxygen speci sinc intracellular factor chang... | D009119 | T039;T067 |
34,639,136 | lecithin inclus cyclodextrin activ srebp signal gut amelior postprandi hyperglycemia cyclodextrin cd one dietari fiber may benefici effect cholesterol andor glucos metabol efficaci mode action remain unclear | D019518 | T079 |
34,639,134 | differenti transcript regul polymorph p codon metabol pathway p transcript factor activ dna damag stress regul express proapoptot gene includ express growth arrest gene subsequ determin fate cell investig function differ polymorph p codon construct isogen line encod polymorph p codon base induc pluripot stem cell endog... | D003062;D005786;D053858;D020641 | T044;T086;T169;T045 |
34,639,131 | anti hepatocellular carcinoma biomolecul molecular target insight report explor avail curat molecul direct hepatocellular carcinoma hcc limit effici well drawback exist molecul led search promis potenti altern understand cell signal mechan propel carcinogenesi driven cell prolifer invas angiogenesi offer valuabl inform... | D058990 | T061 |
34,639,130 | inhibit mitochondri metabol lead select erad cell adapt acid microenviron metabol transform cancer cell lead accumul lactat signific acidif tumor microenviron lactat acidosi well document impact cancer progress negat patient prognosi report cancer cell adapt acidosi signific sensit oxid damag induc hydrogen peroxid hig... | D059016 | T070 |
34,639,129 | earli chang exo endocytosi eae mous model multipl sclerosi correl decreas synapt ribbon size reduc ribbon associ vesicl pool rod photoreceptor synaps multipl sclerosi ms inflammatori diseas central nervous system final lead demyelin demyelin optic neuriti frequent symptom ms recent studi also reveal synaps dysfunct ms ... | D004195;D004705;D005089 | T043;T050 |
34,639,125 | multiom health holist approach better understand role microbiom present special issu focus latest approach health public health microbiolog use multiom | D055442;D054892;D064307;D020543 | T116;T123;T039;T001;T032;T028;T070 |
34,639,124 | integr statist machin learn approach meta analysi bisphenol exposur dataset reveal effect mous gene express within pathway apoptosi cell surviv bisphenol import environment pollut extens studi due differ detriment effect molecular mechan behind effect less well understood like environment pollut bisphenol test various ... | D017209;D000069550;D015233 | T116;T066;T123;T043;T170;T081 |
34,639,123 | gpr inhibit increas glucos uptak hepg cell gpr constitut activ orphan g protein coupl receptor vivo studi suggest involv modul insulin sensit howev precis contribut fulli understood liver major target insulin signal critic involv glucos metabol aim studi examin role gpr regul glucos uptak product human hepatocyt partic... | D007333 | T046 |
34,639,122 | visuo acoust stimul role synapt plastic review literatur brain plastic capac cerebr neuron chang structur function respons experi essenti properti under matur sensori function learn memori process brain repair respons occurr diseas trauma field visual system emerg paradigmat research model basic research studi translat... | D000161;D009473;D014792 | T043;T042;T061;T201 |
34,639,121 | tp acut myeloid leukemia molecular aspect pattern mutat mutat tumor suppressor gene tp associ abysm surviv outcom acut myeloid leukemia aml although common mutat gene cancer occurr observ de novo aml therapi relat aml aml tp mutat serv prognost marker poor respons standard care chemotherapi particular aml aml complex c... | D058990;D009154 | T061;T045 |
34,639,120 | neuroendocrin effect carnitin reproduct impair carnitin quaternari amin involv various cellular process fatti acid uptak oxid glucos metabol regul due neurotroph activ integr use studi sever differ physio patholog condit anorexia nervosa chronic fatigu vascular diseas alzheim diseas male infertil metabol activ carnitin... | D012098 | T040;T079;T081 |
34,639,118 | identif character thermost gh galactosidas anoxybacillus vitaminiphilus wmf applic synthes isofloridosid revers hydrolysi galactosidas produc strain name anoxybacillus vitaminiphilus wmf catalyz revers hydrolysi galactos glycerol produc isofloridosid isol soil galactosidas galv gene clone express escherichia coli galv ... | D006358 | T070 |
34,639,116 | parn like protein regul gene express land plant mitochondria modul mrna polyadenyl mitochondria doubl strand dna genom system regul transcript mrna process translat system differ oper host cell among eukaryot recent decad studi reveal sever plant specif featur mitochondri gene regul polyadenyl status mrna critic stabil... | D018506 | T045 |
34,639,115 | lysophosphatid acid mediat imiquimod induc psoriasi like symptom promot keratinocyt prolifer lparrockpikakt signal pathway psoriasi chronic inflammatori skin diseas recent lysophosphatid acid lpa lpar signal report involv nlrp inflammasom activ macrophag keratinocyt activ produc inflammatori cytokin contribut psoriasi ... | D049109 | T043 |
34,639,112 | constitut photomorphogen enhanc er stress toler arabidopsi interact light signal stress respons recent report plant investig role constitut photomorphogen cop key regul light signal endoplasm reticulum er stress respons arabidopsi cop mutant arabidopsi plant high sensit er stress induc treatment tunicarmycin tm interes... | D059865;D018506;D055537;D056811 | T049;T043;T045 |
34,639,111 | comparison two experiment mous dri eye model inflammatori gene set enrich analysi base multiplex transcriptom approach goal studi explor specif signal pathway relat inflamm two experiment mous dri eye ede model femal cbl mice hous day control desicc environ either treat scopolamin ede n subject extraorbit lacrim gland ... | D004195;D005786;D059467 | T086;T050;T045;T081 |
34,639,110 | effect structur chang induc delet flrapswf sequenc b crystallin chaperon function anti apoptot activ previous show remov residu b crystallin b result fifti percent reduct oligomer mass ten fold increas chaperon like activ studi investig oligomer organ chang delet mutant contribut increas chaperon activ evalu cytoprotec... | D017209 | T043;T116;T123 |
34,639,108 | dye mediat photo oxid biomateri fixat analysi bioinduct mechan properti bovin pericardium use cardiac surgeri extracellular matrix bioscaffold influenc cardiac microenviron modul endogen cellular mechan materi optim cardiac surgeri repair reconstruct investig biocompat bioinduct bovin pericardium fix via dye mediat pho... | D010777 | T090 |
34,639,106 | zebrafish medaka import anim model human neurodegen diseas anim model human neurodegen diseas investig sever decad recent year zebrafish danio rerio medaka oryzia latip becom popular pathogen therapeut studi human neurodegen diseas due small size optic clariti embryo fast develop suitabl larg scale therapeut screen fol... | D004195 | T050 |
34,639,102 | synergist effect venetoclax daratumumab antibodi depend cell mediat natur killer cytotox multipl myeloma prognosi multipl myeloma mm drastic improv owe develop new drug proteasom inhibitor immunomodulatori drug nevertheless mm extrem challeng diseas mani patient still refractori exist therapi thus requir new treatment ... | D004357 | T044;T038;T061 |
34,639,101 | melatonin activ receptor signal pathway mediat protect effect surfact induc increas jejun mucos permeabl rat well function intestin mucos barrier compromis result various diseas chemotherapi radiat chemic exposur includ surfact current approv drug target dysfunct intestin barrier emphas signific medic need one candid d... | D002463 | T043 |
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