PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,684,327 | sensit punish sensit reward effort control transdiagnost mechan under eat disorderobes spectrum although postul eat disord ed obes form part broad spectrum eat weight relat disord yet test empir present studi investig interindividu differ sensit punish sensit reward effort control along edobes spectrum women use data patient eat disord r bp bn healthi control class iiiii obes bariatr patient class ii class iii without bing eat particip complet behavior inhibit behavior activ scale well effort control scale assess sensit punish reward effort control result show patient ed score signific higher punish sensit anxieti compar healthi control class iiiii obes patient differ group differ signific reward sensit patient bing eat compensatori behavior score signific lower effort control patient without bing eat differ temperament profil along edobes spectrum appear continu gradual rather categor impli may meaning includ emot regul impuls regul train treatment ed obes | D012201 | T041 |
34,684,325 | eggshel membran amelior hyperuricemia increas urat excret potassium oxon inject rat hyperuricemia primari caus gouti arthriti metabol disord eggshel membran em effect safe supplement cure pain stiff connect osteoarthr howev effect em hyperuricemia unclear studi determin effect em potassium oxon inject hyperuricemia uric acid creatinin blood urea nitrogen concentr serum xanthin oxidas activ liver measur protein level renal urat transport urat organ anion transport oat glucos transport glut atp bind cassett transport g abcg kidney determin renal histopatholog result demonstr em reduc serum uric acid level increas urin uric acid level hyperuricem rat moreov em downregul renal urat protein express upregul oat abcg chang glut express addit em chang xanthin oxidas activ liver serum em also decreas uric acid uptak oocyt express hurat final em mark reduc renal inflamm serum interleukin level find suggest em exhibit antihyperuricem effect promot renal urat excret regul renal urat transport therefor em may use prevent treatment gout hyperuricemia | D007267 | T169;T121 |
34,684,324 | glycem control metabol adapt respons high fat versus high carbohydr diet data random cross studi healthi subject granular studi metabol respons alter ratio dietari macro nutrient enhanc understand dietari modif influenc patient impair glycem control order studi effect diet enrich fat carbohydr fifteen healthi normal weight volunt receiv cross design random unblind order two week iso calor high fat diet hfd e fat high carbohydr diet hcd e carbohydr mix meal test mmt perform end dietari period examin glucos clearanc kinet insulin incretin hormon level well plasma metabolom profil mmt induc almost ident glycemia insulinemia follow hfd hcd glp level higher hfd vs hcd wherea gip differ hfd compar hcd increas level sever metabolom marker risk develop insulin resist eg branch chain amino acid valin leucin creatin hydroxybutyr acid level normal weight healthi volunt two week hfd vs hcd show similar profil meal induc glycemia insulinemia despit hfd show metabolom pattern impli risk metabol shift toward impair insulin sensit long run | D064368 | T098 |
34,684,322 | total bioavail free hydroxyvitamin equal associ adipos marker metabol trait mexican adult epidemiolog studi suggest relationship total hydroxyvitamin oh adipos metabol trait bioavail oh regul albumin vitamin bind protein vdbp variant gc gene therefor clear bioavail free oh offer addit benefit compar total oh estim magnitud associ aim evalu associ oh total free bioavail adipos metabol trait cross section studi subject health worker cohort studi mexico free bioavail oh calcul base vdbp albumin determin use formula adjust gc gene diplotyp adipos metabol trait measur standard procedur free bioavail oh level correl total oh r respect p total bioavail free oh level negat associ adipos marker viscer adipos index metabol trait metabol syndrom type diabet triglycerid triglycerideshdl c ratio triglyceridesglucos index multivari regress model or find suggest free bioavail oh offer addit advantag total oh regard associ adipos sever metabol trait mexican adult | D050154 | T032 |
34,684,320 | lactobacillus rhamnosus gg deriv extracellular vesicl modul gut microbiota attenu inflammatori dss induc coliti mice ulcer coliti uc relaps remit inflammatori diseas probiot potenti benefici effect prevent uc onset relaps clinic trial lactobacillus rhamnosus gg l rhamnosus gg shown clinic benefit uc patient howev precis mechan unknown aim studi explor effect extracellular vesicl releas l rhamnosus gg lgg ev dextran sulfat sodium dss induc coliti propos under mechan lgg ev protect coliti result show lgg ev could prevent colon tissu damag shorten colon p amelior intestin inflamm inhibit tlr nf b nlrp axi activ consist pro inflammatori cytokin tnf il il il suppress effect upon lgg ev treatment p rrna sequenc show lgg ev administr could reshap gut microbiota dss induc coliti mice alter metabol pathway gut microbiota find propos novel perspect l rhamnosus gg attenu inflamm mediat extracellular vesicl offer consider develop oral gavag lgg ev coliti therapi | D000069196 | T007;T001 |
34,684,319 | effect microbiota composit consumpt quinoa beverag ferment novel xylos metabol l plantarum strain demand novel lactic acid bacteria potenti use probiot along healthi ferment plant base product increas worldwid studi novel lactiplantibacillus plantarum p strain enzymat capac degrad tannin ferment xylos use starter cultur ferment quinoa base beverag probiot potenti select strain evalu healthi volunt twenti particip consum beverag day microbiota chang saliva faecal sampl analyz termin restrict fragment length polymorph rflp next generat sequenc ngs qpcr gastrointestin well digest symptom record result indic consumpt beverag lactiplantibacillus plantarum p probiot dose cfuml increas number lactobacillus fece saliva overal bacteri communiti seem influenc bacterium beverag express divers index specif genera affect reflect chang amplicon sequenc variant consequ lactiplantibacillus plantarum p show potenti categor probiot strain ferment quinoa base beverag | D000074421;D064307 | T028;T001;T032;T168 |
34,684,317 | develop valid short food frequenc questionnair measur dietari intak select immun modul nutrient patient establish peripher arteri diseas nutrient abil modul immun system immun modul nutrient imn may help prevent develop progress atherosclerosi main diseas process under peripher arteri diseas pad current screen tool exist measur imn intak therefor aim project develop valid short food frequenc questionnair ffq measur dietari intak nutrient propos immun modul effect identifi literatur copper iron zinc vitamin c e alpha linolen acid total long chain omega fatti acid arginin glutam acid isoleucin leucin valin patient establish pad item ffq develop measur averag daili intak imn past month particip n recruit flinder medic centr complet ffq follow refer method diet histori reflect usual intak past week mean age particip year male n bland altman analysi result statist non signific p valu p valu nutrient demonstr good agreement two method addit nutrient sensit specif consequ novel item ffq determin promis measur dietari intak imn patient pad compar refer method diet histori recommend investig util biomark explor futur | D004435;D005247;D011795 | T057;T098;T055;T170;T081;T040;T033;T062;T038 |
34,684,316 | antibiot induc gut microbiota dysbiosi damag intestin barrier increas food allergi adult mice background use antibiot affect composit gut microbiota studi suggest colon gut microbiota earli life relat later food allergi still relationship alter intestin microbiota adulthood food allergi unclear method establish three mous model analyz gut microbiota dysbiosi impact intestin barrier determin whether effect increas suscept sever food allergi later life result antibiot induc gut microbiota dysbiosi signific reduc lachnospiracea muribaculacea ruminococcacea increas enterococcacea clostridial time metabol abund chang includ decreas short chain fatti acid tryptophan well enhanc purin chang relat food allergi gut microbiota dysbiosi sensit mice content specif ige igg mice serum signific increas inflammatori respons enhanc dysbiosi gut microbiota caus sensit mice sever allerg symptom ruptur intestin villi decreas tight junction protein tjs expos allergen conclus antibiot induc gut microbiota dysbiosi increas suscept sever food allergi event may due increas intestin permeabl caus decreas intestin tight junction protein increas inflammatori respons | D000069196 | T007;T001 |
34,684,314 | sensori percept oral rehydr solut exercis heat prolong exercis heat elicit number physiolog chang glycogen store low water electrolyt lost sweat howev unclear whether chang provok increas like salti therefor palat oral rehydr solut or twenti seven recreat activ particip n male n femal complet sensori analysi or tradit sport drink ts flavor water placebo pl rest min min bout cycl exercis age predict maximum heart rate hr max c relat humid everi min exercis drink rate use ml beverag sampl base like sweet like salti thirst quench abil overal like nine point hedon scale hydrat status assess chang semi nude bodi mass saliva osmol osm saliva total protein concentr pc min exercis particip lost mean sd bodi mass increas osm pc time point like sweet salti thirst quench abil overal like higher ts pl compar or p howev salti like thirst quench abil or increas min exercis compar exercis p also chang predictor overal like pre exercis rate most determin like sweet salti thirst quench abil p wherea like salti predict overal like post exercis r p appear hedon shift exercis percept salti becom import predictor overal like find support potenti use or valuabl mean hydrat latter stage prolong andor intens exercis heat | D006358;D010465;D012677 | T070;T042;T041 |
34,684,313 | malvidin protect repair peptic ulcer mice allevi oxid stress inflamm peptic ulcer episod caus damag stomach intestin inflammatori cell infiltr oxid stress main player studi investig potenti anthocyanidin malvidin prevent curat peptic ulcer treatment anthocyanidin effect examin gastric ulcer mous model induc ethanol non steroid anti inflammatori drug nsaid ischemia reperfus ir acet acid duoden ulcer induc polypharmaci express level oxid inflammatori gene measur investig mechan anthocyanin activ dose mgkg malvidin prevent gastric ulcer induct ethanol nsaid repair tissu day ir moreov anthocyanidin acceler heal acet acid induc ulcer increas gene express egf cox downregul mmp anthocyanin treatment mitig effect polypharmaci inflamm oxid stress observ intestin addit compound downregul cytokin express tlr upregul hmox il exhibit protect activ mous gut malvidin thus prevent gastric duoden ulcer due promin anti inflammatori antioxid effect gastrointestin tract relat gene express modul increas endogen defens mechan | D018384 | T049 |
34,684,312 | acut l citrullin supplement increas nitric oxid bioavail inspiratori muscl oxygen respiratori perform present studi aim investig whether acut l citrullin supplement would affect inspiratori muscl oxygen respiratori perform twelv healthi male receiv g l citrullin placebo doubl blind crossov design pulmonari function ie forc expir volum forc vital capac ratio maxim inspiratori pressur mip fraction exhal nitric oxid sternocleidomastoid muscl oxygen measur baselin one hour post supplement increment resist breath protocol task failur respiratori muscl resist breath task consist inspir mip follow continu inspir mip task failur sternocleidomastoid muscl oxygen assess use near infrar spectroscopi one hour post l citrullin supplement exhal signific increas p increas preserv end resist breath p contrast differ observ placebo condit pulmonari function mip affect l citrullin supplement resist breath sternocleidomastoid muscl oxygen signific reduc differ note two supplement condit conclus singl ingest g l citrullin increas bioavail respiratori perform inspiratori muscl oxygen | D019587;D012119 | T039;T168;T061 |
34,684,311 | infant formula base milk fat affect immun develop normal birthweight fetal growth restrict neonat piglet infant formula offer altern breast milk normal birth weight nbw immunocompromis intrauterin growth restrict iugr infant although lipid fraction formula often deriv veget oil unclear alter immunolog outcom relat milk fat whether effect differ iugr nbw infant hypothes replac veget oil bovin milk fat infant formula would improv immun develop iugr nbw neonat two day old piglet select nbw n iugr n group anim fed formula base either veget oil veg bovin milk fat milk anim rear day system immun paramet evalu milk fat feed decreas blood neutrophil count improv neutrophil function transient reduc leucocyt express gene relat adapt innat immun well energi metabol follow vitro stimul live staphylococcus epidermidi whole blood h howev interact milk fat type birthweight status thus piglet fed milk fat base formula improv neutrophil matur suppress pro inflammatori respons compar fed veget oil base formula | D001724;D041943 | T032;T168 |
34,684,310 | increas adipos apprais cun bae high predict incid hypertens sun project overweight obes grow worldwid strong associ hypertens clnica universidad de navarra bodi adipos estim cun bae index propos optim indic bodi fat aim investig associ bodi fat captur cun bae index incid hypertens mediterranean popul assess particip sun seguimiento universidad de navarra prospect cohort women initi free hypertens particip complet follow questionnair biennial valid item food frequenc questionnair administ baselin use cox model adjust multipl confound among year median follow interquartil rang year particip report receiv diagnosi hypertens observ strong direct associ progress higher cun bae index baselin incid hypertens follow multivari adjust model men women even adjust bmi kgm show signific associ also non obes particip unit increas cun bae index hypertens risk increas men women respect result remain signific consid longitudin repeat measur chang bodi fat assess cun bae index among differ biennial follow questionnair result emphas import reduc maintain low bodi fat prevent hypertens | D050154 | T032 |
34,684,309 | associ dietari pattern low hdl c among communiti dwell elder north china aim investig associ dietari pattern low hdl c among elder popul live north china data nation cross section survey conduct general inform term live habit health status food intak use h dietari recal three consecut day procur weight edibl oil condiment record anthropometr index blood pressur fast serum lipid measur use standard method dietari pattern deriv food categori exploratori factor analysi multivari logist regress use estim odd ratio low hdl c across quartil dietari pattern among elder particip low hdl c level adjust potenti confound factor particip highest score versus lowest score balanc dietari pattern decreas risk low hdl c ci p trend group bmi kgm compar lowest quartil statist signific negat associ highest score western dietari pattern low hdl c ci p trend group bmi kgm howev greater adher thrifti dietari pattern highest quartil vs lowest quartil associ increas risk low hdl c ci p trend especi subgroup bmi kgm studi reveal urgent develop district specif dietari improv plan dyslipidemia base nutrit status elder popul north china | D005247;D057187 | T040;T056;T055 |
34,684,308 | associ branch chain amino acid bcaa cardiometabol risk factor middl age caucasian women stratifi accord glycem status examin glycem status stratifi relationship total serum branch chain amino acid bcaa concentr cardiometabol risk factor middl age caucasian women studi includ women divid subgroup normoglycem group ng n dysglycem group dg n blood sampl anthropometr paramet blood pressur measur homa ir albumin correct calcium cca fatti liver index fli calcul bcaa concentr higher women dysglycemia bcaa moder correl bmi fli ng group bmi fli total calcium tca cca hbac tghdl c hdl c dg group adjust age bmi correl tca cca hbac hdl c tghdl c remain signific coexist increas bcaa dysglycem status associ mark higher concentr tca cca hbac tg observ dg women low level bcaa multipl regress show tca cca age bcaa signific associ hbac independ bmi dg group conclud dysglycemia particular predispos women signific relationship total bcaa circul calcium hbac relationship independ bmi may reflect pathophysiolog calcium depend mechan connect bcaa metabol disturb | D000083202;D044465 | T080;T098 |
34,684,307 | dietari outcom healthi youngster healthi dad randomis control trial background effect father dietari intak preschool age children explor aim evalu efficaci famili base lifestyl intervent healthi youngster healthi dad chang dietari intak father preschool age children post intervent week month follow compar waitlist control group ii investig associ father child dietari intak method linear mix model estim group time effect dietari outcom measur food frequenc questionnair cohen determin effect size correl test determin associ father child dietari intak result children medium group time effect size identifi week sodium intak percentag energi core food energi dens nutrient poor ednp food prepack snack find sustain month follow father medium larg group time effect size identifi week energi intak sodium intak percentag energi core food ednp food confectionari dietari variabl except sodium effect sustain month moder strong associ exist father child dietari intak dietari variabl conclus although research requir studi provid preliminari support target father agent chang improv dietari intak preschool age children | D000072001;D005220 | T033;T099;T061;T055 |
34,684,305 | associ nutrit status hospit mortal covid critic ill patient icu coronavirus diseas covid becom one lead caus death worldwid impact poor nutrit status increas mortal prolong icu intens care unit stay critic ill patient well document studi aim assess nutrit status bmi bodi mass index affect hospit mortal critic ill covid patient method conduct retrospect studi analys medic record covid patient admit intens care unit univers clinic hospit wroclaw poland | D017052;D007362;D009752 | T080;T033;T093;T073 |
34,684,304 | dietari satur fat health us guidelin evid base last decad seen near paper review total data satur fat cardiovascular outcom altogeth demonstr lack rigor evid support continu recommend either limit consumpt satur fatti acid replac polyunsatur fatti acid paper unfortun consid process lead recent us dietari guidelin american countri nation nutrit polici recent reconfirm recommend limit satur fat less total energi intak base insuffici inconsist evid continu cap satur fat intak also fail consid import effect food matrix overal dietari pattern satur fatti acid consum | D006262;D018673 | T080;T170;T078 |
34,684,303 | intak unprocess process meat associ cardiovascular diseas overview systemat review conduct overview systemat review summar review cohort studi intak unprocess process meat risk cardiovascular diseas cvd coronari heart diseas chd stroke systemat review cohort studi publish januari august identifi systemat literatur search pubm embas web scienc qualiti review conduct assess overal confid result review rate use amstar qualiti evid meta analysi grade use nutrigrad three review includ meta analys unprocess red meat cvd n stroke n unprocess poultri stroke n process meat cvd n chd n stroke n overal confid result review rate critic low meta evid grade moder posit associ unprocess red meat stroke moder posit associ process meat chd stroke associ meta evid grade low low conclus associ unprocess process meat cvd major subtyp cvd extens investig | D004435;D000078202 | T040;T033;T170;T038 |
34,684,302 | triacylglycerid phospholipid egg yolk differ influenc immunostimul properti egg white protein part whole egg egg white protein embed lipid matrix could modifi present immun system allergen properti present studi examin impact main egg lipid compon triacylglycerid phospholipid earli event sensit egg end balbc mice expos intragastr egg lipid egg lipid fraction alon mixtur egg white protein th promot proinflammatori effect investig result highlight egg lipid fraction respons th adjuv effect point differ influenc triacylglycerid phospholipid bioavail immunomodul properti egg white protein triacylglycerid promot type respons small intestin level phospholipid reduc solubl ew protein induc th skew lymphoid intestin tissu may direct impact develop egg allergi | D007114 | T061 |
34,684,301 | alter gut microbiota korean children autism spectrum disord autism spectrum disord asd neurodevelopment disord character social behavior impair recent studi suggest gut microbiota play critic role asd pathogenesi herein investig fecal microflora korean asd children determin gut microbiota profil associ asd specif fecal sampl obtain children asd age match children exhibit typic develop systemat bioinformat analysi reveal composit gut microbiota differ asd typic develop children tdc moreov total amount short chain fatti acid metabolit produc bacteria increas asd children phylum level found signific decreas relat bacteroidet abund asd group wherea actinobacteria abund signific increas furthermor found signific lower bacteroid level higher bifidobacterium level asd group tdc group genus level function analysi microbiota asd children predict sever pathway includ genet inform process amino acid metabol associ asd pathogenesi although research need determin whether differ asd tdc actual relat asd pathogenesi result provid evid alter gut microbiota children asd possibl provid new perspect diagnosi therapeut approach asd patient | D000069196 | T007;T001 |
34,684,300 | altern dietari pattern american low carbohydr diet decad long dietari experi embodi dietari guidelin american dga focus limit fat especi satur fat higher carbohydr intak coincid rapid escal epidem obes type diabet td contribut progress cardiovascular diseas cvd diet relat chronic diseas moreov lack flexibl dga pertain low carbohydr approach align contemporari trend toward precis nutrit argu person level dietari carbohydr high prioriti base evid american wide spectrum metabol variabl toler high carbohydr load obes metabol syndrom td condit strong associ insulin resist condit exacerb increas dietari carbohydr improv restrict carbohydr low carbohydr diet ground across time span human evolut well establish biochem principl support multipl clinic trial human demonstr consist improv multipl establish risk factor associ insulin resist cardiovascular diseas american diabet associ ada recent recogn low carbohydr eat pattern effect approach patient diabet despit evid base low carbohydr diet reflect dga dga dietari pattern demonstr univers effect address need mani american recogn lack wide avail treatment obes metabol syndrom td safe effect sustain argument altern low carbohydr dietari pattern compel | D050528;D018673 | T170;T061 |
34,684,171 | systemat review assess impact hyperbar oxygen therapi glycaemia peopl diabet mellitus background object hyperbar oxygen recognis treatment rang medic condit includ treatment diabet foot diseas number studi report impact hyperbar oxygen treatment glycaem control patient undergo treatment diabet foot diseas systemat review consid impact hyperbar oxygen glycaemia peopl diabet materi method prospect prospero regist prospero registr crd systemat review elig studi publish english pubm medlin embas databas base follow search term hyperbar oxygen therapi hbo hyperbar oxygen glycaem control diabet diabet mellitus diabet hbac data extract pre determin pilot data collect form individu assess bias result total elig public identifi screen six articl report statist signific reduct blood glucos hyperbar oxygen treatment two articl report statist signific increas peripher insulin sensit two articl also identifi statist signific reduct hbac follow hyperbar oxygen treatment conclus emerg evid suggest reduct glycaemia follow hyperbar oxygen treatment patient diabet mellitus exist studi relat small cohort potenti underpow addit larg prospect clinic trial requir understand precis impact hyperbar oxygen treatment glycaemia peopl diabet mellitus | D003924;D017719;D006931 | T047;T061 |
34,684,170 | role bradykinin receptor etiopathogenesi chronic spontan urticaria background object chronic spontan urticaria csu distress skin condit manifest red swollen itchi sometim pain hive wheal appear skin recent csu associ bradykinin releas previous discov main trigger hereditari angioedema attack studi role bradykinin receptor br br etiopathogenesi csu materi method total individu patient csu healthi subject recruit studi csu diagnos accord standard protocol dermatolog assess skin symptom level bradykinin receptor determin popul cd cd cd lymphocyt well cd cd cd cd cd cd monocyt addit urticaria activ score sum day ua assess correl br br express result statist signific higher concentr br express lymphocyt found patient csu compar control group p moreov statist signific posit correl observ ua brbr express cd cd cell p r conclus bradykinin receptor elev select popul lymphocyt symptomat csu patient compar healthi control indic role etiopathogenesi diseas | D000080223;D014581 | T047 |
34,684,169 | periop risk stratif need improv assess surgeri anesthesia pilot studi background object numer score system introduc modern medicin none score system assess anesthet surgic risk patient predict morbid mortal need postop intens care unit admiss aim studi compar anesthet surgic score current use better evalu periop risk morbid mortal materi method pilot prospect observ studi enrol patient schedul elect surgeri anesthet surgeri risk assess use american societi anesthesiologist asa scale physiolog oper sever score enumer mortal morbid p possum acut physiolog chronic health evalu apach ii surgic apgar score sas score real estim length stay los regist result obtain sever statist signific posit correl asa score p possum p r asa score sas p r asa score apach ii p r predict los asa score p r predict los p possum p r predict los apach ii p r signific negat correl predict los real los asa class sas p observ found statist signific differ predict actual los p conclus anesthet surgic sever score use togeth provid clearer inform mortal morbid los asa scale associ surgic score sever score present better imag patient progress periop period studi apach ii best predictor mortal follow p possum sas p possum score asa scale may complementari term preoper physiolog factor provid valuabl inform postop outcom | D000758 | T061 |
34,684,168 | predict differenti thyroid cancer behavior role genet molecular marker thyroid cancer rank ninth place among newli diagnos cancer case differenti thyroid cancer behavior vari indol extrem aggress current predict cancer prognosi main base clinicopatholog featur direct consequ cell tissu microenviron alter alter includ genet chang cell cycl disord estrogen receptor express abnorm enhanc epitheli mesenchym transit extracellular matrix degrad increas hypoxia consecut neovascular process repres specif genet molecular marker predict thyroid cancer develop progress prognosi conclus evalu cancer genet molecular pattern addit clinicopatholog featur contribut identif patient potenti wors prognosi essenti sinc play crucial role decis make regard initi surgeri postop treatment follow date larg divers methodolog use differ studi frequent lead contradictori result evalu true signific predict marker compar studi conduct | D000230;D013964 | T191 |
34,684,167 | comparison periop outcom use da vinci si x xi robot platform baba robot thyroidectomi background object robot thyroidectomi via bilater axillo breast approach baba first introduc korea becom standard method thyroid remov worldwid introduct robot surgic system enabl patient benefit baba robot thyroidectomi good postop excel cosmet result date studi compar benefit four current avail da vinci robot system si x xi baba robot thyroidectomi determin da vinci model suitabl baba robot thyroidectomi present studi compar periop outcom patient underw baba robot thyroidectomi use four da vinci model materi method retrospect studi evalu outcom patient n underw baba robot thyroidectomi use four da vinci system clinicopatholog data includ oper time compar substudi compar da vinci model si substudi b compar model si x xi result substudi compar da vinci si system found statist signific differ two group wherea substudi b found oper time shorter patient underw baba robot thyroidectomi da vinci xi system si x system conclus da vinci model xi system benefit patient undergo baba robot thyroidectomi shorten oper time | D065287;D012371 | T090;T061 |
34,684,166 | stimul heal non infect stagnat diabet wound copper oxid impregn wound dress background object copper wide spectrum biocid also play key role angiogenesi wound heal antibacteri wound dress impregn copper oxid microparticl cod recent clear us fda regulatori bodi treatment acut chronic wound includ diabet wound object evalu capac cod stimul heal non infect stagnat wound diabet patient initi treat standard care soc dress materi method trial divid three follow phase week screen patient treat soc dress week treatment cod appli twice week week follow patient treat soc dress wound condit size assess clinic evalu wound imag artifici intellig system result follow month cod treatment clear reduct mean wound area p increas granul tissu p reduct fibrin p patient non weight bear wound reduct wound size even dramat p conclus result studi show statist signific influenc cod wound heal hard heal wound diabet patient strong support notion copper oxid impregn dress enhanc wound heal direct larger control studi conduct substanti find | D003300;D003920 | T047;T121;T196;T123 |
34,684,165 | gastrodia elata blume zanthoxylum schinifolium siebold zucc mix extract suppress platelet aggreg thrombosi background object blood vessel thrombosi caus blood circul disord lead various diseas current various antiplatelet anticoagul drug aspirin warfarin heparin non vitamin k antagonist oral anticoagul noac use major drug treatment wide rang thrombosi howev drug side effect possibl caus intern bleed due poor hemostasi taken long period time materi method nbsp gastrodia elata blume ge zanthoxylum schinifolium siebold zucc zs known exhibit hemostat antiplatelet effect tradit medicin use long time studi investig effect mix extract ge zs mjge platelet aggreg plasma coagul result found mjge inhibit collagen adp induc platelet aggreg vitro addit collagen adp induc platelet aggreg also inhibit dose depend manner platelet mice oral administ mjge ex vivo howev compar aspirin mjge prolong rat tail vein bleed time vivo show signific effect increas prothrombin time pt activ partial thromboplastin time aptt conclus result suggest mjge use potenti anticoagul improv antithrombot efficaci | D031668;D013927;D032106 | T046;T002 |
34,684,164 | manag acut colon diverticul covid era scope review background object covid pandem health system worldwid made major chang organ delay diagnosi treatment across broad spectrum patholog concern surgeri evid reduct elect emerg activ particular benign patholog acut diverticul identifi reduct emerg room present mild form increas sever form aim review discov new data emerg present patient acut diverticul covid pandem current manag defin better methodolog surgic decis make method conduct scope review trial analyz five point reduc hospit access patient diverticul prefer treatment non complic diverticul role ct scan primari evalu percutan drainag treatment chang surgic decis make prefer treatment strategi complic diverticul result found decreas emerg access patient diverticular diseas increas incid complic diverticul prefer treatment conserv non complic form patient covid relat pneumonia percutan drainag abscess surgeri delay reserv diffus periton sepsi conclus covid pandem observ increas number complic form diverticul total number decreas possibl due delay hospit ambulatori present fear contract covid observ greater tendenc treat sever form conserv mean drainag surgeri necessari prefer open approach delay oper | D000086382;D004238;D004239 | T047;T067 |
34,684,163 | bilater proxim tibiofibular synostosi caus osteochondroma year old high activ male first literatur background object one case unilater proxim tibiofibular synostosi caus osteochondroma report report first well document bilater case proxim tibiofibular synostosi caus osteochondroma case report year old high activ male patient bilater proxim tibiofibular synostosi caus osteochondroma suffer persist knee pain present conserv method fail patient treat bilater open resect connect bone histopatholog find confirm preoper diagnosi patient return sport three week surgeri continu soccer train six week surgeri discuss case report present success treatment bilater proxim tibiofibular synostosi caus osteochondroma bilater open resect connect bone | D001859;D015831;D013580 | T191;T019 |
34,684,162 | long term pain characterist manag follow minim invas spinal decompress open laminectomi fusion spinal stenosi background object compar long term pain characterist chronic manag follow minim invas spinal mis decompress open laminectomi fusion lumbar stenosi materi method studi cohort includ patient minimum year postop follow undergo either mis decompress laminectomi fusion spinal claudic primari outcom interest chronic back leg pain intens secondari outcom measur includ pain frequenc day chronic use non opioid analges narcot medic medic cannabinoid continu intervent pain treatment result total patient lumbar spinal stenosi underw one two level surgeri lumbar spinal stenosi april juli patient underw mis decompress patient underw open laminectomi instrument fusion fusion group higher percentag patient experienc moder sever back pain compar patient mis decompress group p contrast found signific differ report leg pain group fusion group patient describ back leg pain persist throughout day compar mis decompress group p trend toward higher chronic depend analges medic repetit pain clinic treatment found fusion group conclus mis decompress treatment degen spinal stenosi result decreas long term back pain similar leg pain outcom compar open laminectomi instrument fusion surgeri | D013123;D013130 | T061;T020 |
34,684,161 | predict judkin left cathet size left transradi coronari angiographi simpl chest radiograph echocardiograph index background object appropri cathet select conduct transradi coronari angiographi cag help shorten examin time prevent vascular complic lower medic expens howev cathet select made base practition experi almost case therefor undertook studi defin radiolog echocardiograph indic would enabl physician anticip appropri cathet select materi method retrospect studi undergo transradi diagnost cag establish center februari april patient success underw angiographi jl cathet defin control group patient success underw angiographi cathet replac jl higher defin switch group identifi predictor appropri cathet select radiolog echocardiograph indic analyz result total patient switch group patient control group analyz studi averag age year radiograph index switch group exhibit signific higher mediastin thorac ratio vs p addit mediastin cardiac ratio signific greater switch group vs p aortic root diamet use echocardiograph index signific larger switch group compar control group mm vs mm p multivari logist regress model mediastin cardiac ratio ci p increas aortic root ci p signific associ cathet chang conclus mediastin cardiac ratio aortic root diamet provid help effect indic appropri cathet select transradi coronari angiographi | D062906;D017534 | T023;T074 |
34,684,160 | provis palliat care covid pandem systemat review ambulatori care organ unit state background object ambulatori outpati healthcar organ continu respond covid global pandem use array initi sustain continu palliat care continu palliat care major crise previous accomplish howev global pandem present new challeng us healthcar industri materi method systemat review queri four research databas identifi applic studi relat provis palliat care pandem outpati organ within unit state result two primari facilit ongo provis palliat care outpati segment unit state healthcar industri technolog advanc care plan research also identifi two primari barrier outpati set impact continu palliat care lack resourc access care conclus systemat review identifi facilit barrier palliat care initi unit state assist futur outpati ambulatori care provid global level pandem associ public health initi continu | D000086382;D058873 | T047;T067 |
34,684,159 | rare evolut pneumopericardium patient covid pneumonia treat high flow nasal cannula infect sever acut respiratori syndrom coronavirus caus coronavirus diseas covid reveal offici pandem world health organ march current pandem third decad worst term suffer death relat covid repres unpreced challeng medic communiti patient around world high resolut comput tomographi chest hrct fundament tool manag diagnosi diseas imag play essenti role diagnosi manifest diseas complic correct use interpret imag test essenti pneumomediastinum report rare covid patient one first group share experi uncommon parenchym complic covid spontan pneumothorax pneumomediastinum also new onset bronchiectasi cyst find pneumopericardium also unusu herebi report rare case spontan pneumopericardium patient covid pneumonia treat high flow nasal cannula hfnc | D000086382;D011026 | T047;T067 |
34,684,158 | radiolog physiolog predictor ipf mortal background object idiopath pulmonari fibrosi ipf variabl clinic cours rang asymptomat progress respiratori failur purpos studi evalu novel clinic paramet ipf patient receiv anti fibrot agent materi method januari januari identifi ipf patient okinawa chubu hospit clinic inform obtain laboratori data pulmonari function test pft result chest imag includ soft tissu thick high resolut comput tomographi hrct pattern diagnosi result mean age patient men women mean bodi mass index twenti four activ smoker median number pack per year regard laboratori find mean white blood cell wbc lactat dehydrogenas ldh kreb von den lungen kl valu respect pft mean percent predict fvc percent predict total lung capac percent predict function residu capac frc percent predict diffus capac lung carbon monoxid dlco respect chest radiolog find soft tissu thick right th rib mm regard chest hrct pattern show definit usual interstiti pneumonia uip pattern show probabl uip pattern eight show indetermin uip pattern treatment patient receiv pirfenidon patient took nintedanib mean observ period month patient die median surviv time month multivari analysi adjust age show soft tissu thick hazard ratio hr confid interv ci p valu percent frc hr ci p valu robust predictor ipf mortal conclus ipf patient treat anti fibrot agent soft tissu thick right th rib shown chest radiograph frc novel predictor ipf mortal | D054990 | T047 |
34,684,157 | epidemiolog pattern hepat c lithuania chang surveil background object viral hepat c infect import public health concern worldwid one major global caus death morbid earli identifi cation infect peopl togeth provis proper treatment key strategi use prevent hcv infect howev data regard epidemiolog pattern hep atiti c lithuania limit aim research evalu trend acut hcv case regist via nation surveil system lithuania materi method incid rate calcul data stratifi gender age group place resid urban rural lithuanian counti case record crude incid rate hepat c defin number new infec tion per peopl one year time period linear regress appli evalu ate ir trend period result case acut hepa titi c regist incid rate rang case per peopl statist signific decreas trend incid rate found studi period p almost acut hcv infect record via nation surveil system individu age year conclus male age year live citi might import factor understand epidemiolog pattern hcv lithuania although number hcv case record lithuania decreas countri one highest ir compar european countri show new approach hepat c virus screen strategi need | D016174;D006526 | T047;T005 |
34,684,156 | fragil fractur risk factor manag elder given progress age western popul fragil fractur market grow socioeconom impact fragil fractur common elder negat impact qualiti life limit autonomi increas disabl decreas life expect differ caus contribut develop fractur frail individu among target fragil patient develop fractur may repres greatest challeng current diagnost tool suffer limit studi summar current evid manag fragil fractur discuss risk factor prevent diagnosi actual limit clinic therapeut option put forward new idea scientif investig | D058866;D011788 | T047;T078 |
34,684,155 | epidemiolog musculoskelet injuri adult athlet scope review background object sport relat musculoskelet injuri msk common health issu athlet lead reduc perform aim scope review synthet avail evid injuri incid rate iir type site affect musculoskelet msk system adult athlet materi method perform scope review pubm databas limit search olymp sport result identifi total paper examin full purpos review archeri sport highest risk injuri upper extrem marathon lower extrem triathlon weightlift bodi bust major sport examin muscletendon strain ligament sprain common msk diagnos athlet karat footbal sport highest iir depend method use calcul conclus scope review highlight general lack dishomogen collect data msk athlet | D001265;D005538;D009140;D012916 | T056;T047;T037 |
34,684,154 | comparison perform valid calcul establish anaerob lactat threshold run background object studi aim compar calcul run veloc anaerob lactat threshold clt determin mathemat model metabol simul two establish threshold concept onset blood lactat accumul obla mmoll modifi maxim deviat method mdmax addit threshold concept correl perform differ endur run event materi method ten sub elit runner perform sprint test cycl ergomet adjust isokinet mode set cadenc rpm determin maxim lactat product rate vla max grade exercis test treadmil determin maxim oxygen uptak vo max run veloc obla mdmax clt compar correl run perform various distanc result mean differ clt ms ms compar mdmax p obla p respect clt indic moder good concord establish threshold concept mdmax icc obla icc comparison threshold concept clt exhibit compar correl assess run perform clt r mdmax r obla r conclus data show clt appli determin endur perform run due consider individu physiolog profil clt offer physiolog justifi approach assess athlet endur perform | D019344;D012420 | T056;T121;T109;T123 |
34,684,153 | chang lumbar spinal stenosi symptom six year period communiti dwell peopl background object high preval lumbar spinal stenosi lss negat impact qualiti life elder well known howev longitudin time cours lss symptom remain unclear purpos studi clarifi longitudin time cours associ factor lss symptom period six year communiti materi method studi conduct data prospect collect retrospect design subject age rang year interview lss symptom use special design valid questionnair follow studi perform mail subject studi popul respond consid presenc osteoarthr oa knee hip may influenc particip answer questionnair analysi perform subject subject without either knee hip oa chang lss symptom initi year survey investig multipl logist regress analysi use detect risk factor lss symptom presenc six year follow result six year follow half subject show lss symptom initi analysi becam lss negat lss negat becam lss posit multipl logist regress analysi lower roland morri disabl questionnair rdq score posit lss symptom initi analysi detect predict factor presenc lss symptom six year follow total number subject well either knee hip oa conclus half subject lss posit initi assess still experienc improv symptom even year mean lss symptom time cours vari person person predict factor presenc lss symptom six year follow period rdq score posit lss symptom | D015207;D013130 | T047;T020 |
34,684,152 | anticholinerg burden geriatr ward inpati background object anticholinerg drug use pharmacotherapi elder person common despit increas risk side effect examin preval anticholinerg drug use total anticholinerg drug burden among patient admit acut care geriatr ward poland materi method cross section studi subject hospit geriatr ward patient condit assess comprehens geriatr assess anticholinerg cognit burden acb scale use estim total anticholinerg load result mean patient age year burden least one anticholinerg drug clinic signific anticholinerg burden observ subject patient dementia risk fall sever disabl signific higher total acb score compar group receiv oper characterist roc curv reveal total acb score signific associ dementia risk fall total acb score signific associ sever disabl conclus patient admit acut care geriatr ward anticholinerg cognit burden score compar patient popul found associ low elev level anticholinerg burden dementia risk fall elev anticholinerg burden level found associ sever disabl despit recommend use anticholinerg older adult medic still common prescrib studi necessari defin characterist anticholinerg medic close associ negat outcom elder popul | D018680;D003704 | T048;T121 |
34,684,151 | comparison postop recoveri manual target control infus remifentanil bariatr surgeri background object earli postop recoveri surgeri key point patient safeti comfort moreov oper room turnov depend recoveri time aim assess method remifentanil administr manual mi target control infus tci could reduc patient time recoveri room studi patient recoveri time regist compar among group materi method enrol morbid obes patient prospect studi undergon bariatr surgeri hospit lithuanian univers health scienc kauno kliniko sevofluraneremifentanil anaesthesia perform patient patient random assign manual infus mi control group target control infus tci group method administr remifentanil patient wake surgeri record spontan breath airway reflex recoveri time time extub eye open recoveri orient begin follow oral command tci group also document remifentanil concentr blood automat infus pump result patient differ demograph valu durat remifentanil infus found remifentanil consumpt tci group lower p despit lower remifentanil consumpt tci group patient demonstr longer total recoveri time control group patien vs p conclus studi show upon compar tci method mi manual infus produc better result postop patient recoveri addit higher dose remifentanil consum use mi conclus dosag recommend high qualifi anaesthesiologist favour morbid obes patient compar tci method | D050110;D009767;D015742 | T047;T121;T061;T109 |
34,684,150 | cope strategi health relat qualiti life pregnant women sar cov infect background object matern death associ sar cov infect remain sever time greater general popul signific factor might contribut higher mortal morbid rate psycholog impact diseas pregnanc therefor current studi main object assess pregnant women react cope stress covid diseas influenc overal health qualiti life healthcar facil materi method cross section studi includ pregnant women success complet standard form assess topic interest compris hospit anxieti depress scale short form health survey cope orient problem experienc inventori scale core outcom measur questionnair qualiti patient perspect questionnair result unemploy pregnant women live poverti rural area higher sar cov infect rate pregnanc face higher anxieti level depress rate associ increas physic burden exhaust howev find influenc hospit care sinc remain unchang among covid non covid matern unit except signific lower technic compet score covid facil conclus pandem consequ emerg addit outbreak occur care must priorit addit physic burden experienc pregnant women contract covid well psycholog emot mental health support | D000086382;D037841 | T047;T098;T067 |
34,684,149 | fibromuscular dysplasiacarotid web angio ct imag rare caus ischem stroke background object carotid web caw intim variant fibromuscular dysplasia may constitut one rare caus acut ischem stroke ai object studi determin preval caw patient ai transient ischem attack tia base headneck ct angiographi cta polish cohort studi materi method retrospect studi perform analyz electron clinic imag data regard patient ai tia hospit year author institut final sampl consist patient underw headneck cta age year women headneck cta studi independ evalu two radiologist patient clinic condit assess nation institut health stroke scale nihss admiss discharg respect result patient identifi caw preval caw final sampl pts good qualiti cta caw group patient ai includ diagnos recurr cryptogen stroke signific differ presenc caw gender age nihss score recurr cryptogen stroke conclus studi demonstr caw may underrecogn entiti lead cerebrovascular event diagnosi caw depend high level awar comprehens analysi neuroimag studi find support hypothesi worthwhil perform cta determin etiolog ischem stroke particular predict factor identifi | D002545;D005352;D000083242;D020521 | T047;T046 |
34,684,148 | patient percept recoveri dental implant placement background object success rate surgic dental implant insert high howev knowledg patient recoveri still lack health relat qualiti life hrqol questionnair gain popular field medicin present survey assess percept recoveri surgic placement dental implant materi method forti individu women men mean age year fill questionnair evalu patient percept recoveri consecut day post surgeri confound factor includ age gender oral habit smoke bruxism bone qualiti tactil evalu quantiti implant locat number implant implant type length diamet one stage vs two stage need bone graft result serious difficulti found swell becam minim day follow eat everyday food abil enjoy everyday food maxim pain averag pain day analges consumpt day limit daili routin mouth open speech day swallow sleep day within day measur attain minim level gender implant locat anterior vs posterior signific predictor variabl exert differ characterist delay recoveri conclus patient expect general recoveri within day dental implant placement women experi delay recoveri implant place intercanin area result postop eat difficulti near one week number implant place appoint effect post treatment recoveri | D015921 | T074 |
34,684,147 | exert desatur higher mortal non desatur copd background object exert desatur ed often overlook chronic obstruct pulmonari diseas copd aim investig impact ed mortal predictor ed copd materi method cohort copd patient clinic stabl wide rang sever enrol ed defin oxyhemoglobin satur puls oximetri spo drop spo six minut walk test mwt cox regress analysi use estim hazard ratio hr three year mortal result total patient studi includ ed n non ed n group fvc predict valu fevfvc fev predict valu dlco maxim inspiratori pressur spo mwt gold stage copd sever signific differ ed non ed group univari analysi low minim spo p high maxim heart rate p mwt signific relat ed multivari analysi adjust age gender bodi mass index mwd fev mmrc gold stage exacerb hs crp fibrinogen mortal rate ed group higher non ed group p hr ci death averag surviv time ed shorter non ed group day vs day p conclus ed higher mortal non ed copd copd assess ed especi patient low minim spo high maxim hr mwt | D029424;D016138 | T047;T169;T056 |
34,684,146 | sepsi new challeng futur perspect evolv diseas precis medicin way sepsi still remain lead caus hospit death world | D057285;D018805 | T091;T047;T061;T046 |
34,684,145 | prognost factor post recurr surviv stage ii iii colorect carcinoma patient background object studi aim evalu prognost factor post recurr surviv local local advanc colorect cancer patient materi method total patient stage iii high risk stage ii colorect cancer prospect enrol patient underw oper treatment primari tumor adjuv fluorouracil base chemotherapi result three year period cohort patient stage iii high risk stage ii colorect cancer screen follow patient diseas recurr surviv rate year recurr respect median post recurr surviv time month surviv analysi show age diagnosi p gender p elev postop ca p tumor histolog adenocarcinoma vs mucin vs signet ring tumor p tumor stage ii vs iii p signific influenc post recurr surviv recurr interv metastat site relat surviv follow recurr multivari analysi show older age hr mucin tumor hr tumor express ca baselin hr independ associ surviv follow recurr conclus baselin patient tumor characterist larg predict patient outcom diseas recurr recurr interv local local advanc colorect cancer found prognost factor post recurr surviv older age male gender stage iii mucin histolog poor prognost factor diseas recur stage ii patient remark post recurr surviv compar stage iii patient | D002288;D015179 | T191 |
34,684,144 | cannabi dopaminerg effect induc hallucin patient parkinson diseas cannabi product contain tetrahydrocannabinol thc cannabinoid emerg promis therapeut agent treatment medic condit chronic pain thc elicit psychoact effect modul dopaminerg neuron therebi alter level dopamin brain case report highlight complex associ medicin cannabi health risk associ use year old male parkinson diseas experienc worsen tremor vivid hallucin despit therapi optim attempt discov patient took cannabi chronic back pain pharmacogenom pgx test indic presenc variant comt htra gene variant could increas dopamin level predispos patient visual hallucin cannabi discontinu patient hallucin began slowli dissip cannabi use continu expand gain accept legal medicin cannabi affect respons drug patient case suggest cannabi use combin dopamin promot drug especi patient genet variant increas risk vivid hallucin condit support import consid herb drug interact pgx data perform medic safeti review | D002188;D010300 | T047;T121;T002;T109;T167 |
34,684,143 | role mirna therapeut tool sickl cell diseas background object sickl cell disord scd paradigmat exampl complex monogen disord scd character product abnorm hemoglobin primarili deoxygen state make erythrocyt suscept intracellular hemoglobin polymer function studi affirm dysregul mirna enhanc clinic sever amelior effect scd mirna effect regul reduc pace cell cycl progress reduc iron level influenc hemolysi oxid stress import increas globin gene express enhanc effect hydroxyurea result review highlight role play key mirna hemoglobinopathi especi hematopoiesi erythroid differenti sever anemia make mirna attract molecular tool innov therapeut approach conclus era target medicin mirna mimic antagomir may promis induc hbf synthesi could amelior clinic sever scd | D000755;D035683 | T047;T114;T123 |
34,684,142 | epidemiolog footbal relat sudden cardiac death turkey background object sudden cardiac death scd particular among elit footbal attract much attent recent time howev limit inform exist footbal relat scd turkey autopsi base studi sport relat sudden death turkey rare often small sampl size address studi aim determin popul base incid profil footbal relat scd nation turkey materi method due lack nation data issu footbal relat scd non elit competit recreat footbal januari decemb identifi dual independ identif screen onlin media report death explor sex age group season phase exercis descript statist utilis age specif mortal rate proport mortal rate calcul result total footbal relat scd identifi crude mortal rate per popul fatal male mean age year age year record highest mortal rate three time risk age year rr ci age record highest age specif proport mortal rate death highest risk occur play footbal n anoth death n occur within h play almost fatal n occur particip recreat footbal conclus studi identifi footbal relat scd common occur recreat footbal among male age year recommend male age particip recreat footbal encourag seek pre particip heart health check given valu autom extern defibril a respond hospit cardiac arrest futur research explor feasibl effect a prevent footbal relat scd turkey includ train first respond cardiopulmonari resuscit a use | D005538;D012916 | T056 |
34,684,141 | atyp chronic myeloid leukemia new develop molecular diagnosi treatment atyp chronic myeloid leukemia bcr abl negat acml rare hematolog entiti includ group myelodysplast mds myeloprolif mpn overlap syndrom character aggress cours high rate acut myeloid leukemia aml transform dismal outcom clinic present includ splenomegali leukocytosi neutrophilia left shift granulocytosi accompani granulocyt dysplasia sometim multilineag dysplasia past year diseas incid like underestim diagnosi base morpholog featur recent improv knowledg molecular biolog mdsmpn neoplasm made possibl distinguish acml overlap syndrom base next generat sequenc among common mutat gene sever involv jak stat mapk rock signal pathway could action target therapi alreadi use clinic practic open way tailor treatment acml howev current data avail small sampl allogen transplant remain curat option elig patient | D054438;D009190 | T191;T046 |
34,684,140 | preval erectil dysfunct associ cardiovascular risk factor patient myocardi infarct background object studi estim preval sever erectil dysfunct associ cardiovascular risk factor patient myocardi infarct materi method studi includ men age year diagnos myocardi infarct examin depart prevent cardiolog vilnius univers hospit santaro kliniko anthropometr characterist blood pressur lipid profil blood glucos level preval cardiovascular risk factor evalu intern index erectil function use assess patient erectil function result total patient analys mean age year patient three four five establish cardiovascular risk factor respect patient diagnos dyslipidaemia arteri hypertens diabet smoke posit famili histori insuffici physic activ overal preval erectil dysfunct score mild mild moder moder sever patient mean age signific differ sever group p studi demonstr negat correl age total score questionnair r p arteri hypertens frequent patient erectil dysfunct p cardiovascular risk factor distribut similar conclus erectil dysfunct common patient myocardi infarct sever age depend preval cardiovascular risk factor high arteri hypertens signific frequent patient erectil dysfunct | D002318;D007172;D009203 | T047 |
34,684,139 | lemierr syndrom case present rare possibl life threaten condit lemierr syndrom present rare condit life threaten one syndrom first describ andr lemierr compris oropharyng infect common associ anaerob bacteria fusobacterium necrophorum intern jugular vein thrombophleb possibl secondari septic metastasi common site lung brain describ rare case diagnos infecti diseas depart septemb | D057831;D018805;D013924 | T047;T046 |
34,684,138 | influenc sar cov pandem diagnosi treatment cervic dysplasia background object risk develop invas cancer increas covid pandem especi romania incid diseas high due limit medic educ broad screen studi object analyz number patient admit differ type cervic dysplasia treatment appli lesion sar cov pandem compar period year pandem materi method retrospect studi took place obstetr gynecolog clinic iii og iii emerg counti hospit craiova sar cov pandem sp month non pandem period npp studi includ patient patholog pap smear result patient includ studi clinic examin colposcopi patient low grade dysplasia manag conservatori manner reevalu six month patient high grade dysplasia admit excision biopsi lesion excis fragment sent patholog anatomi laboratori histopatholog examin result studi reveal decreas half number patient admit cervic intraepitheli neoplasia cin lesion pandem compar period year number biopsi excision procedur decreas factor three pandem period compar year conclus sar cov pandem found patient admiss rate diagnosi treatment almost four time lower hospit restrict dictat cancerprecanc manag sp may assum differ due fear becom infect sar cov due hospit context poor screen perform high cervic cancer incid influenc sp may result increas sever case relat condit | D000086382;D018290 | T191;T047;T067 |
34,684,137 | low bodi mass index predict factor postop infecti complic ureterorenoscop lithotripsi background object studi aim evalu predict factor postop fever pof ureterorenoscop lithotripsi ursl materi method total consecut patient underw ursl urinari stone diseas gifu municip hospit chuno kosei hospit april januari enrol studi patient antibiot routin administ intraop next day surgeri use rigid andor flexibl ureterorenoscop depend stone locat ursl stone fragment use holmium yag laser fragment stone manual remov much possibl use stone basket cathet ureter stent place end surgeri case result median age bodi mass index bmi patient year kgm respect median oper durat min common ursl relat complic pof patient patient rate antibiot administr ureter stent insert surgeri signific higher without pof multivari analysi bmi associ pof ursl signific differ predict pof surgeri patient bacteriuria receiv antibiot surgeri conclus low bmi signific associ pof ur ursl | D008096;D014514;D014545 | T047;T031;T061 |
34,684,136 | clostridium difficil covid general data ribotyp clinic form treatment experi largest infecti diseas hospit western romania background object coronavirus diseas covid caus infect sever acut respiratori syndrom coronavirus sar cov clinic manifest primarili relat pulmonari system case also develop gastrointestin event diarrhea nausea vomit abdomin pain materi method conduct observ retrospect studi infecti diseas clinic victor babe hospit timi counti order assess incid outcom risk factor clostridium difficil infect cdi covid patient result covid case hospit st septemb th april case cdi identifi case hospit onset cdi eight case communiti onset healthcar associ cdi random polymeras chain reaction ribotyp clostridium difficil perform six case random case test posit ribotyp percentag case recov complic discharg higher among covid patient cdi p hospit stay day versus day longer among covid patient cdi p presenc previous hospit p administr antibiot hospit stay increas risk cdi among covid patient mean adjust cci admiss lower among control p two case exitus strict cdi relat one case posit ribotyp conclus cdi complic outcom covid patient especi comorbid previous expos healthcar system face covid pandem widespread extens use antibiot clinician remain vigil possibl cdi sar cov co infect | D000086382;D016360;D003141;D003428 | T007;T047;T067 |
34,684,135 | effect task specif train cognit sensorimotor exercis propriocept spastic gait speed stroke patient random control studi background object common problem stroke patient includ loss propriocept spastic impair gait purpos studi examin effect task specif train tst combin cognit sensorimotor exercis cse propriocept spastic gait speed stroke patient materi method thirti seven subject random divid three group tst cse group experiment n tst group experiment ii n convent physic therapi train group control group n evalu perform commenc train eight week train initi electrogoniomet use evalu propriocept variat composit spastic score css myotonepro use evalu spastic addit walk test use assess gait speed result train experiment group show signific improv propriocept compar experiment ii control group p css gastrocnemius muscl tone gmt gait speed among three group experiment group differ signific eight week train compar control group p conclus find suggest tst combin cse provid signific improv propriocept spastic gait speed | D020521;D000071939 | T047;T061 |
34,684,134 | systemat review case report neck tongu syndrom background object neck tongu syndrom nts rare character unilater upper neck occipit pain paresthesia ipsilater hemispher tongu due neck movement treatment nts main conserv symptom caus rational treatment remain controversi studi aim provid framework nts treatment clinic practic base recent treatment direct materi method case report publish past year august search medlin embas pedro databas sinc establish manag nts search term neck tongu syndrom case report critic apprais checklist case report use qualiti assess case report descript analysi nts symptom intervent result review result among studi search six case report select analyz base eight criteria symptom includ neck pain ipsilater tongu paralysi head turn intervent six four studi show immedi symptom relief manual therapi exercis respect conclus base review evid manag physic therapi chiropract therapi conserv method manual therapi exercis patient neck tongu syndrom recommend | D019547;D014059 | T023;T184 |
34,684,133 | critic flicker fusion frequenc narrat review review present current knowledg usag critic flicker fusion frequenc cff human anim model studi cff wide applic differ field especi indic cortic arous visual process medicin cff may help diagnost purpos exampl epilepsi minim hepat encephalopathi given environment studi limit number method applic dive hyperbar medicin current research also show relationship cff electrophysiolog method electroencephalographi human eye detect flicker hz report show possibl distinguish steadi modul light hz futur research use cff need better understand util applic | D005425;D006501 | T047;T034 |
34,684,132 | associ n acetyltransferas polymorph suscept head neck cancer meta analysi meta regress trial sequenti analysi background object n acetyltransferas nat nat gene polymorph accord slow rapid acetyl phenotyp role develop head neck cancer hncs herein aim evalu associ nat nat polymorph suscept hncs updat meta analysi materi method search comprehens perform four databas web scienc scopus pubmedmedlin cochran librari juli effect size odd ratio along confid interv ci comput trial sequenti analysi tsa public bias sensit analysi conduct result twenti eight articl includ eight studi report nat polymorph twenti five studi report nat polymorph involv meta analysi result show individu slow acetyl nat polymorph higher risk hnc ci p subgroup analysi ethnic control sourc genotyp method found signific factor associ nat polymorph hnc risk tsa identifi amount inform larg enough studi need establish associ conclus slow acetyl nat polymorph relat high risk hnc howev relationship nat polymorph risk hnc | D001191;D006258 | T116;T191;T126 |
34,684,131 | anticoagul use independ risk factor higher hospit mortal patient show alveolar hemorrhag diffus lung diseas background object bronchoalveolar lavag bal common perform evalu diffus lung diseas occasion identifi alveolar hemorrhag howev clinic impact alveolar hemorrhag risk factor patient diffus lung diseas clarifi materi method retrospect analyz medic record patient underw bal evalu diffus lung diseas januari decemb alveolar hemorrhag defin progress hemorrhag bal fluid presenc hemosiderin laden macrophag bal fluid logist regress analysi perform assess associ alveolar hemorrhag factor result sixti subject enrol studi alveolar hemorrhag observ subject idiopath interstiti pneumonia acut respiratori distress syndrom interstiti pneumonia autoimmun featur drug induc lung injuri eosinophil pneumonia adenocarcinoma system lupus erythematosus use anticoagul signific risk factor alveolar hemorrhag odd ratio p patient alveolar hemorrhag requir intub mechan ventil frequent vs p higher hospit mortal rate vs p without alveolar hemorrhag conclus alveolar hemorrhag observ various etiolog use anticoagul signific risk factor alveolar hemorrhag patient alveolar hemorrhag show sever respiratori failur higher hospit mortal without alveolar hemorrhag | D006470;D017563 | T047;T046 |
34,684,130 | effect three surgic therapi increas keratin mucosa surround dental implant peri implant pilot studi background object purpos pilot studi evalu clinic outcom three differ method increas keratin mucosa km surround dental implant peri implant materi method twenti implant site peri implant divid porcin collagen matrix cm group seven implant site apic posit flap apf group eight implant site free gingiv graft fgg group five implant site km width clinic paramet probe pocket depth ppd bleed probe bop measur time point surgeri day surgeri result regard km width group signific differ increas horizont vertic km width cm fgg group greater km apf group decreas ppd three group apf fgg show signific differ ppd compar fgg group show signific differ ppd compar bop valu also reduc group compar apf fgg group show signific decreas bop conclus three surgic therapi present favor result increas km surround implant compar fgg group cm show similar result increas km around dental implant peri implant | D015921;D057873 | T047;T074 |
34,684,129 | analysi effici prognost valu sentinel node techniqu oral squamous cell carcinoma seven year background object purpos studi analys diagnost prognost effici sentinel lymph node biopsi techniqu slnb materi method prospect observ studi perform hospit complex santiago de compostela chus spain februari june studi includ patient diagnos oscc stage ttnm result patient present sn sentinel node posit major present subcapsular affect howev one case also present extracapsular affect use kaplan meier curv determin averag surviv estim sn patient month ci month ci sn patient p sn patient present ci p cancer relat mortal term diagnost perform sn sentinel node test sensit specif ppv npv obtain analysi use roc receiv oper characterist curv reveal auc ci p conclus slnb seem adequ techniqu detect hidden metastas | D002294;D006258;D009062 | T191 |
34,684,128 | transvagin sonograph evalu cesarean section scar nich pregnanc prospect longitudin studi background object investig preval cesarean section cs scar nich pregnanc assess transvagin ultrasound imag relat scar measur demograph obstetr variabl nich evolut final pregnanc outcom materi method prospect observ studi use transvagin sonographi examin uterin scar women week gestat scar defin visibl pregnant status area hypoechogen myometri discontinu lower uterin segment identifi cs scar nich defect defin indent site cs scar depth least mm sagitt plane measur hypoechogen part cs nich two dimens myometri thick adjac nich residu myometri thick rmt second third trimest pregnanc full lower uterin segment lus thick myometri layer thick measur thinnest part scar area two independ examin measur cs scar non select subset patient n descript analysi use assess scar visibl intraclass correl coeffici icc calcul show strength absolut agreement two examin scar measur factor associ cs scar nich includ matern age bmi smoke status previous vagin deliveri obstetr complic histori previous uterin curettag investig clinic inform pregnanc outcom complic obtain hospit electron medic databas result scar visibl women among visibl cs scar incid cs scar nich intra interobserv agreement cs scar nich measur excel icc respect compar subgroup women term cs scar nich n non nich n statist signific correl matern age p bmi p gestat diabet p smoke status p previous vagin deliveri cs p nich develop uterin scar nich seen women undergon uterin curettag compar without uterin curettag p observ absenc correl uterin scar nich first trimest pregnanc mode deliveri p two case uterin scar dehisc confirm follow trial vagin deliveri conclus base ultrasonographi examin cs scar nich remain visibl half case visibl cs scar first trimest pregnanc could reproduc measur transvagin scan previous uterin curettag associ increas risk uterin nich format subsequ pregnanc uterin scar dehisc might potenti relat cs scar nich | D002585;D002921 | T046;T079;T061 |
34,684,127 | frozen eleph trunk aortic arch diseas differ devic differ patholog frozen eleph trunk techniqu fet requir use pre assembl hybrid prosthesi consist standard dacron vascular portion replac aortic arch stent graft compon place proxim descend thorac aorta dta anterograd proxim descend thorac aorta europ two hybrid prosthes avail e evita open plus hybrid stent graft system provid jotec hechingen germani thoraflextm hybrid vascutek inchinnan scotland recommend use extens patholog arch case acut chronic aortic dissect degen aneurysm intramur hematoma fet approach allow replac whole arch one stage option direct treatment proxim descend thorac aorta base stent compon creat safe land zone endovascular treatment distal remark featur techniqu possibl perform proxim zone zone distal anastomosi arch allow easier distal anastomosi reduc hypotherm circulatori arrest time decreas risk paraplegia earli result promis accord recent seri rate develop post oper renal insuffici rang risk stroke mortal aim articl provid knowledg use applic fet procedur differ aortic situat | D000784;D019917 | T047;T061;T046 |
34,684,126 | patient physician perspect asthma therapi romania result multicent survey background object patient behaviour attitud belief relat asthma treatment shown influenc adher therapi level asthma control survey aim assess level asthma control patient report behaviour attitud expect relat diseas romanian patient materi method cross section quantit survey perform februari march enrol specialist physician experienc asthma manag asthma patient care result patient enrol mild asthma moder asthma sever asthma previous month asthma symptom exacerb emerg room visit common sampl analys signific higher figur sever asthma patient p import treatment goal asthma patient particip activ daili live physician prevent asthma exacerb valuat treatment goal differ patient sever asthma mild moder form base patient respons attitud cluster identifi empow savvi patient pessimist non complier anxious struggler empow savvi lowest frequenc sever asthma highest adher mainten therapi highest level confid effect asthma medic opposit attitud cluster anxious struggler contain patient sever asthma higher score worri asthma therapi better self report knowledg treatment contrast proport take mainten therapi breath difficulti conclus asthma control romania remain poor frequent exacerb hospit differ treatment goal found patient physician differ asthma sever group suggest need patient centr approach | D001249;D010820 | T097;T047 |
34,684,125 | role hyaluron acid sport relat tendinopathi narrat review tendinopathi complex clinic condit rise incid preval particular sport practic return play affect patient adequ function structur recoveri tendon ultim goal avoid high risk recurr perspect local therapi alongsid exercis show promis result despit evid suggest hyaluron acid ha inject effect treatment tendinopathi current recommend manag condit includ intervent ha seem effect therapeut option manag sport relat tendinopathi studi larger sampl size need confirm avail find narrat review analyz avail literatur rational use ha manag tendon injuri particular sport relat tendinopathi | D001265;D052256 | T047;T037 |
34,684,124 | algorithm approach superior th percentil upper refer limit high sensit troponin threshold safe discharg emerg depart background object high sensit cardiac troponin hs tni import indic acut myocardi infarct ami among patient present chest discomfort emerg depart ed aim determin reliabl hs tni cut compar various valu baselin singl measur algorithm approach materi method retrospect review hs tni valu patient present ed chest discomfort june june evalu diagnost accuraci ami beckman coulter access hs tni assay compar th percentil upper refer limit url base manufactur claim newli design url korean popul algorithm approach result total patient underw hs tni test ed review diagnos ami singl measur baselin hs tni cut ngl show best perform whole popul sensit specif negat predict valu npv posit predict valu ppv algorithm use baselin h hs tni valu show sensit specif npv ppv algorithm use cut ngl singl measur h symptom onset initi level ngl chang ngl rule patient cut ngl singl measur chang ngl rule patient conclus algorithm approach use serial measur could help differenti ami patient patient could safe discharg ed ensur patient triag accur undergo unnecessari test cut valu previous studi differ countri effect korean popul | D009203;D010351 | T058;T047 |
34,684,123 | possibl adren involv long covid syndrom background signific number patient covid experi prolong symptom known long covid frequent symptom fatigu cognit dysfunct describ patient suffer long covid adren involv highlight method patient describ long covid symptom persist month negativ molecular swab test main symptom weak brain fog dizzi muscular joint pain routin lab panel inflamm anemia thyroid liver function conduct moreov salivari cortisol dhea determin use comput adren stress index asi result test negat except asi show low level free cortisol patient start hydrocortison acet supplement conclus long covid symptom could explain adren involv due covid action adren gland iatrogen side effect high glucocorticoid therapi covid infect salivari cortisol determin effect establish correct recoveri plan | D000086382 | T047;T067 |
34,684,122 | comparison clinic process outcom patient coronavirus infect outbreak background object coronavirus infect covid pandem affect emerg depart ed manag viral transmiss necessit use isol room person protect equip treat suspect patient fever delay time first encount patient therebi increas length stay los ed aim compar delay ed los clinic process covid period pre covid period moreov intend evalu aforement delay affect patient outcom materi method conduct singl center retrospect studi korea patient fever compar covid period march august pre covid period march septemb compar overal ed los individu time variabl includ initi diagnost test laboratori test radiographi specif diagnost test comput tomographi treatment process antibiot logist regress analysi conduct identifi associ hospit admiss patient data result enrol patient pre covid period respect patient fever remain ed longer durat covid period pre covid min vs covid min p total time perform laboratori test radiographi display signific differ two period particular time patient arriv ed time issu order time antibiot administr delay covid period pre covid min vs covid min p logist regress analysi hospit admiss identifi ed los independ factor period conclus delay encount patient fever result longer ed los covid period howev possibl increas hospit admiss rate | D000086382 | T047;T067 |
34,684,121 | microbiom chang type diabet treatment systemat review background object although role gut microbiom type diabet td pathophysiolog evid current systemat review meta analys analyz td treatment main focus metabol outcom object studi evalu microbiom metabol chang differ type treatment td patient materi method systemat search pubm wiley onlin librari scienc direct cochran librari electron databas perform random control clinic trial publish last five year includ td subject evalu composit gut microbiom alongsid metabol outcom convent altern glucos lower therapi select microbiom chang evalu alongsid metabol outcom term bacteria taxonom hierarchi intestin flora biodivers appli intervent result total elig studi involv particip review four trial investig oral glucos lower treatment three studi implement bariatr surgeri rest analyz probiot prebiot synbiot effect common alter increas abund firmicut proteobacteria parallel improv glycem control bariatr surgeri especi roux en gastric bypass led highest varieti chang bacteria phyla lower divers post treatment signific biodivers result present improv glycem control conclus anti diabet treatment induc growth deplet bacteria gut microbiom similar healthi individu achiev trial research must explor effect strategi promot benefici bacteria lower divers eventu reach non td microbiom | D003924;D015390;D000069196;D064307;D019936;D058616 | T007;T047;T001;T168;T032;T028;T061 |
34,684,120 | role contrast enhanc harmon endoscop ultrasound intervent endoscop ultrasound last decad contrast enhanc harmon endoscop ultrasound ch eus emerg import diagnost tool diagnosi differenti sever gastrointestin diseas key advantag ch eus influx washout contrast target lesion observ real time accur depict microvasculatur ch eus establish evid base techniqu complementari b mode eus differenti solid appear structur character mass lesion improv stage gastrointestin pancreatobiliari cancer last year interest increas use ch eus intervent procedur tissu acquisit tumor ablat biliari drainag manag pancreat fluid collect aim narrat review evalu avail evid futur expect ch eus intervent eus | D010190 | T191 |
34,684,119 | effect covid pandem work condit dentist poland turkey background object due specif work condit dental profession repres group high risk infect covid pandem mani way influenc work environ aim studi evalu effect covid pandem work condit dentist poland turkey materi method studi anonym onlin questionnair conduct among thedentist two countri poland turkey survey consist general question covid pandem infect work histori well work condit pandem chi squar test fisher exact test fisher freeman halton test continu yate correct use compar qualit data result studi conduct total particip men women age mean age particip year posit covid test result among dentist poland found signific higher turkey time dental procedur covid pandem poland turkey signific increas usag nffp nffp mask surgic gown covid pandem compar pre covid period clear higher p reusabl full face half face elastomer respir increas use turkey covid pandem decreas dentist incom poland signific high turkey conclus covid pandem influenc work condit dentist mani dentist got infect pandem dental procedur time increas protect equip usag becom higher studi analyz work condit dentist covid pandem conduct better plan futur decis taken govern author | D000086382;D058873 | T047;T067 |
34,684,118 | identif gingiv microcircul use laser doppler flowmetri patient orthodont treatment longitudin pilot studi background object orthodont tooth movement associ inflammatori respons aim studi identifi gingiv microcircul use laser doppler flowmetri patient orthodont treatment materi method longitudin pilot studi perform particip select use non probabl consecut sampl twenti five subject total six four women two men compli criteria treatment oral hygien index gingiv index probe depth level epitheli attach gingiv microcircul evalu laser doppler flowmetri integr paramet integr primari basal flow ipbf integr total secondari real flow itsrf differ integr dbi particip result increas gingiv blood flow identifi time interv differ arch orthodont treatment b ipbf itsrf treatment identifi min treatment initi stage compar differ time interv observ increas gingiv perfus th th nd hour arch c dbi found statist signific differ p nitinol group inch among time interv h h h within day interv observ flow increas three time greater basal flow day conclus healthcar profession must identifi inflammatori process treatment observ discontinu use harm method clinic practic | D005881 | T023;T024 |
34,684,117 | updat review pemphigus diseas clinician may encount varieti skin condit present vesiculobul lesion everyday practic pemphigus vulgari pemphigus foliaceus iga pemphigus paraneoplast pemphigus repres spectrum autoimmun bullous dermatos pemphigus famili pemphigus famili diseas character signific morbid mortal consid risk associ delay diagnosi misdiagnosi potenti overlap clinic featur treatment evalu suspect pemphigus diseas often requir thorough clinic assess laboratori test diagnosi focus individu biopsi histopatholog direct immunofluoresc addit laboratori method use diagnosi includ indirect immunofluoresc enzym link immunosorb assay recent advanc includ anti cd therapi improv efficaci reduc morbid pemphigus treatment contribut present updat pathophysiolog clinic featur diagnost work medic manag pemphigus improv strategi diagnosi clinic assess review newer treatment option discuss | D001327;D010392;D012872 | T047 |
34,684,116 | effect vitamin supplement muscl status old patient recov covid infect background object vitamin addit effect miner homeostasi play key role muscl metabol vitamin supplement involv muscl recoveri damag consequ either patholog high intens exercis context aim studi analyz effect vitamin muscl fit elder patient recoveri phase sar cov covid infect materi method pilot studi conduct soria nort health center studi consist doubl blind trial two group men placebo vitamin supplement n group treatment vitamin cholecalciferol iuday placebo carri week circul hematolog biochem paramet total protein glucos vitamin urea uric acid aspart aminotransferaseglutam oxaloacet transaminas alanin aminotransferaseglutam pyruv transaminas creatin kinas lactat dehydrogenas aldolas gamma glutamyl transferas myoglobin hormon cortisol testosteron determin respiratori function test fev respiratori flow also studi physic fit test six minut walk test mwt use result vitamin supplement observ serum creatin kinas level return optim valu chang suggest protect role vitamin muscl catabol compar placebo term physic test result observ slight non signific improv although patient report feel better conclus vitamin supplement produc decreas indic muscl damag may ultim contribut improv health status qualiti life patient suffer covid recoveri process | D000086382;D014808 | T047;T067 |
34,684,115 | psychosoci role bodi imag qualiti life head neck cancer patient futur hold review literatur background object well known among cancer cancer head neck hnc major impact patient qualiti life disfigur anxieti disabl physic psycholog symptom affect peopl hnc extent suicid rate categori patient exceed patient pancreat cancer aim review summar publish literatur describ sever bodi imag qualiti life impair patient hnc time examin psychosoci function associ intervent implement improv bodi imag qualiti life materi method conduct literatur search januari june includ electron search six major databas pubm sciencedirect proquest psycinfo psycharticl scopus review refer articl screen record articl met elig criteria result numer studi conduct analyz various psycholog variabl still lack standard assess bodi imag percept bi qualiti life result small scale test intervent poor result conclus expect longitudin studi describ flow bodi imag problem mediat balanc factor associ bodi imag allow research design method aim limit bodi imag disord thus improv qualiti life patient head neck cancer | D006258;D013405 | T033;T191 |
34,684,114 | eu covid digit certif strike reason balanc mobil need public health need fight high aggress virus sar cov compel govern put place measur name health protect constrain mani freedom enjoy includ freedom movement nation within european union order encourag facilit return free movement european parliament launch covid digit certif spirit debat center around use certif still ongo among scholar mani point uncertainti relat covid immun privaci issu risk discriminatori effect author highlight critic aspect argu covid digit certif current approv version effect help prevent spread infect promot free movement uphold right health much possibl howev also stress need thorough inform campaign illustr advantag limit document order avoid creat fals sens secur public opinion may wrong assum emerg overcom good | D000086382;D011634 | T091;T047;T067 |
34,684,113 | mortal predict patient sever acut kidney injuri requir renal replac therapi background object acut kidney injuri aki remain serious health condit around world relat high morbid mortal longer hospit durat wors long term outcom aim studi estim signific relat factor poor outcom patient sever aki requir renal replac therapi rrt materi method retrospect analyz data patient n sever aki requir rrt within year period analyz outcom discharg hospit also compar clinic data surviv non surviv patient examin possibl relat factor poor patient outcom logist regress use analyz odd ratio patient mortal relat factor result n patient renal function improv rrt stop n patient die n patient remain dialysi depend day discharg hospit period year outcom investig patient chang statist signific administr vasopressor aminoglycosid sepsi pulmonari edema oliguria artifici pulmonari ventil apv patient age renal caus aki aki cardiac surgeri combin two rrt method dysfunct three organ systol blood pressur bp mmhg diastol bp mmhg sequenti organ failur assess sofa score day first rrt procedur relat factor lethal patient outcom conclus mortal rate among patient sever aki requir rrt high patient death signific predict caus aki sepsi cardiac surgeri clinic cours oliguria pulmonari edema hypotens acidosi lesion organ need continu renal replac therapi | D058186;D007362 | T047;T073;T093;T037 |
34,684,112 | pax pax ryk express cleft affect tissu background object cleft lip without cleft palat one common type congenit malform transcript factor pair box pax pax receptor like tyrosin kinas ryk previous associ format orofaci cleft exact possibl involv interact tissu specif cleft type remain uncertain limit number morpholog studi analyz specif factor cleft affect tissu due ethic aspect limit amount avail tissu materi studi analys presenc pax pax ryk immunoposit structur within differ cleft affect tissu assess possibl involv cleft morphopathogenesi materi method cleft affect tissu collect non syndrom orofaci cleft patient cleft correct surgeri patient unilater cleft lip patient bilater cleft lip patient isol cleft palat control group oral caviti tissu obtain patient without cleft lip palat evalu number immunoposit structur cleft affect tissu control group semiquantit count method use non parametr statist method kruskal walli h test mann whitney u test spearman rank correl use result statist signific differ number pax pax ryk posit cell notifi control patient group multipl statist signific correl factor found cleft affect tissu group conclus pax pax ryk variabl involv interact postnat morphopathogenesi orofaci cleft pax associ format unilater cleft lip pax relat toward isol cleft palat stabl presenc ryk cleft type indic possibl particip differ facial cleft format | D002971;D002972 | T019 |
34,684,111 | alter serca express breast cancer background object calcium ca signal critic normal function various cellular activ howev abnorm chang cellular ca contribut patholog condit includ various type cancer mainten intracellular ca level achiev tight regul process help maintain ca homeostasi sever type regulatori protein involv control intracellular ca level includ sarcoendoplasm reticulum srer ca atpas pump serca maintain ca level releas srer total three atpas srer ca transport atpa gene exist encod sever isoform whose express profil tissu specif recent becom clear abnorm serca express activ associ various type cancer includ breast cancer breast carcinoma repres cancer type affect women wide varieti patholog clinic condit materi method use cbioport breast cancer patient data kaplan meier plot demonstr high atpa atpa express associ reduc patient surviv result present studi found signific differ serca specif type express seri breast cancer cell line moreov bioinformat analysi indic atpa atpa express high alter patient breast cancer conclus overal present data suggest serca gene specif expressioncan possibl consid crucial target control breast cancer develop progress | D001943 | T191 |
34,684,110 | long term clinic function ultrasound outcom recreat athlet achill tendon ruptur griffith versus tenolig background object purpos retrospect studi compar long term clinic function ultrasound outcom recreat athlet treat two percutan techniqu griffith g tenolig techniqu tt materi method recreat athlet year age affect acut achill tendon ruptur aatr treat g tenolig techniqu recruit clinic function outcom evalu use achill tendon ruptur score atr aofa ankl hindfoot score vas pain satisfact questionnair ultrasound analysi focal thicken hypoecho area presenc calcif tendin alter normal fibrillar architectur result patient includ treat g tt patient resum sport activ pre injuri level case g tt g group averag questionnair atr point aofa vas satisfact vas pain tt group atr point aofa vas satisfact vas pain tt group show signific higher satisfact return sport activ within shorter time g group ultrasound check show signific greater incid thicken alter fibrillar architectur treat tendon three infect report includ one deep g two superfici tt group two ruptur tenolig group follow trauma conclus long term follow g tt valid techniqu treatment aatr recreat athlet achiev compar clinic function result howev tt seem higher patient satisfact rate faster return sport physic activ fewer ultrasound sign tendin final cost devic make techniqu expens | D000125;D013708 | T023;T037 |
34,684,109 | diabet wound heal scienc diabet mellitus increas preval chronic metabol diseas character prolong hyperglycemia lead long term health consequ estim impair heal diabet wound affect approxim patient diabet mellitus often result lower limb amput subsequ high econom psychosoci cost hyperglycem environ promot format biofilm make diabet wound difficult treat review present updat regard recent advanc understand pathophysiolog diabet wound focus impair angiogenesi neuropathi sub optim chronic inflammatori respons barrier disrupt subsequ polymicrobi infect follow current futur treatment strategi design tackl various patholog associ diabet wound given alarm increas preval diabet subsequ diabet wound imper futur treatment strategi target multipl caus impair heal diabet wound | D003920;D017719;D006943 | T033;T047 |
34,684,108 | outcom enamel matrix deriv periodont regener diabet condit background object enamel matrix deriv emd biomateri use periodont regen therapi due properti stimul cementum develop bone synthesi diabet chronic condit affect heal predispos infect aim review evalu current studi avail applic result emd periodont regen therapi diabet condit materi method five databas pubm researchg scopus web scienc googl scholar search relev articl use specif keyword differ combin inclus criteria clinic trial case report case studi anim studi publish english periodont treatment bone defect includ emd perform diabet condit result articl result search five studi publish met inclus criteria select current review human studi use emd infraboni defect show favor result follow anim studi periodont regener reduc diabet rat conclus emd might promot bone heal use diabet condit regen periodont therapi due limit number studi data requir sustain effect emd therapi diabet set | D016301;D003746;D003921 | T116;T047;T050;T123 |
34,684,107 | procalcitonin level covid patient strong associ mortal icu accept underserv inner citi popul background object studi aim identifi demograph clinic factor time critic care consult associ mortal intens care unit accept predomin afro caribbean popul first wave covid pandem materi method retrospect singl center observ cohort studi includ covid patient receiv critic care consult march april first wave covid pandem state univers new york downstat health scienc univers result patient critic care consult surviv expir bivari level age blood urea nitrogen blood neutrophil percentag signific associ mortal mean age survivor vs non survivor p also signific associ neutrophil mortal univari logist regress model quartil vs quartil odd ratio confid interv p trend multivari analys increas level procalcitonin c reactiv protein signific associ mortal adjust age sex raceethn procalcitonin quartil vs quartil odd ratio confid interv p trend contrast higher platelet level correl signific decreas odd mortal quartil vs quartil odd ratio ci p trend factor elev procalcitonin level associ intens care unit accept conclus procalcitonin show greatest magnitud associ death likelihood intens care unit accept bivari level data suggest procalcitonin reflect pneumonia sever covid infect thus may help intensivist identifi covid patient requir intens care unit level care | D000086382;D000077740 | T123;T116;T047;T067 |
34,684,106 | retrospect clinicopatholog analysi peri implant lesion background object peri implant common find among patient dental implant consensus regard treatment diseas mani case surgic treatment common practic histopatholog analysi integr part suggest protocol present studi investig clinic histopatholog paramet lesion mimick peri implant correl outcom follow data materi method studi includ consecut biopsi taken peri implant patient result three common diagnos fibro epitheli hyperplasia pyogen granuloma peripher giant cell granuloma case recurr lesion studi group recurr rate highest peripher giant cell granuloma versus pyogen granuloma fibro epitheli hyperplasia differ recurr rate statist signific p conclus studi emphas necess submit tissu peri implant case histopatholog analysi sinc local aggress lesion peripher giant cell granuloma pyogen granuloma compris near half case studi differ clinic radiograph characterist peri implant lesion | D006101;D057873 | T047;T046 |
34,684,105 | assess predict factor covid outcom retrospect cohort studi metropolitan region paulo brazil background object aim retrospect cohort studi search individu sociodemograph environment predictor covid outcom materi method conveni sampl covid confirm patient year mean year femal sought treatment emerg unit public health system diadema brazil march octob includ primari data collect medic record sex age occupationeduc onset symptom presenc chronic diseasestreat outcom death non death secondari socioeconom environment data provid depart health result mean time spent covid symptom onset admiss health system day princip compon analysi summar secondari sociodemograph data poisson regress model show time symptom onset health system admiss higher younger peopl least advantag region avail electr sewag network water suppli garbag collect multipl logist regress model show associ age diabet obes death outcom hypertens sex show signific associ conclus identif vulner group may help develop health strategi prevent treatment covid | D000086382 | T047;T067 |
34,684,104 | investig factor affect qualiti life patient mild moder alzheim diseas term patient caregiv background object chronic diseas limit medic treatment import goal alzheim diseas ad treatment provid better qualiti life qol purpos studi investig factor affect qol patient mild moder ad term patient caregiv materi method seventi three home dwell patient ad caregiv particip prospect cross section studi patient ask cognit depress self rate part qol questionnair caregiv ask patient sociodemograph inform sleepi activ daili live proxi rate part qol questionnair result self rate qol higher provid proxi rate cognit p sleepi p depress p correl self rate qol patient independ level activ daili live correl proxi rate qol p regard predict qol accord linear regress analysi follow statist signific depress total score depress cognit self rate instrument activ daili live proxi rate p conclus individu factor psycholog import determin qol patient ad object condit independ patient daili life import caregiv evalu qualiti life ad patient import rememb patient caregiv differ prioriti prioriti taken account plan treatment program | D000544;D011788 | T048;T047;T078 |
34,684,103 | associ spiritu well hope health anxieti sever patient advanc coronari arteri diseas background object health anxieti one common problem patient coronari arteri diseas present studi test whether health anxieti sever could predict spiritu well hope patient advanc coronari arteri diseas materi method cross section studi patient advanc coronari arteri diseas recruit hospit healthcar center iran patient complet self report scale includ spiritu well scale adult hope scale short health anxieti inventori hierarch multipl regress analys use empir explor relat among variabl result result indic patient report higher level hope p spiritu well p report lower level health anxieti agenc p score signific negat predictor health anxieti sever addit religi spiritu score p shown signific negat predict health anxieti level howev pathway compon hope existenti spiritu signific predictor conclus find present studi indic spiritu well hope could import factor determin health anxieti adult coronari arteri diseas role worthi explor help improv health anxieti patient coronari arteri diseas | D003324 | T047 |
34,684,102 | cutoff valu provid ideal intraven patient control analgesia accord intens postop pain retrospect observ studi background object cutoff valu analyz provid ideal intraven patient control analgesia pca could reduc rescu analges antiemet requir base grade postop pain intens ppi materi method pca regimen patient retrospect analyz alloc three group low moder high ppi grade group l h respect base numer rate score obtain h postop opioid non opioid analges dose convert fentanyl equival dose dose fen op dose fen nonop respect primari endpoint cutoff valu paramet result respect pca set reduc rescu analges antiemet requir group l requir background infus rate bir mlh bolus volum ml lockout interv min group requir bir mlh bolus volum ml lockout interv min group h requir bir mlh bolus volum ml lockout interv min assess analges dose reduc rescu analges requir dose fen op least g fentanyl regardless group dose fen nonop g g g l h group respect assess analges dose reduc rescu antiemet requir dose fen op g group l g group h dose fen nonop g g g group l h respect conclus ideal pca reduct rescu analges antiemet achiev adjust pca set drug dosag care cutoff valu depend expect grade ppi especi ideal pca provid adjust lockout interv bolus volum rather bir appli smaller bolus dose shorter lockout interv increas ppi grade | D016058;D010149 | T047;T184;T061 |
34,684,101 | clinic characterist actinomyc viscosus bacteremia background object actinomyc speci part normal flora human rare caus diseas uncommon caus diseas human clinic featur actinomycosi describ various anatom site face bone joint respiratori tract genitourinari tract digest tract central nervous system skin soft tissu structur affect easi identifi actinomycosi sometim mimic cancer due recognit new diagnost method appli actinomyc easili identifi speci level recent studi also highlight differ among actinomyc speci report case actinomyc viscosus bacteremia cutan actinomycosi materi method year old male develop fever day progress right lower leg erythemat swell blood cultur isol yield actinomyc speci identifi actinomyc viscosus sequenc rrna gene addit search term actinomyc actinomycosi cross referenc bacteremia blood cultur blood stream januari juli infecti diseas caus speci viscosus januari juli also review result patient recov well intraven ampicillin treatment poor oral hygien confirm dental examin diseas relaps follow period case actinomycosi treat penicillin howev clinic alert risk factor evalu identif actinomyc speci prevent inappropri antibiot intervent also compil total case actinomyc bacteremia conduct onlin databas search conclus summari describ case fever progress cellul actinomyc speci isol blood cultur identifi actinomyc viscosus rrna sequenc cellul improv pathogen direct antibiot evalu risk factor patient actinomyc bacteremia identif actinomyc speci recommend success treatment | D000196;D016470 | T047 |
34,684,100 | chang plasma vegf pedf level patient central serous chorioretinopathi background object retin pigment epitheliopathi hyperperm choroid vessel postul involv pathogenesi central serous chorioretinopathi csc imbalanc level vascular endotheli growth factor vegf pigment epithelium deriv factor pedf previous implic develop chorioretin diseas character increas vascular permeabl aim compar plasma level proangiogen vegf antiangiogen pedf patient acut csc patient chronic csc control materi method vegf pedf level measur use multiplex immunoassay enzym link immunosorb assay correl diseas durat assess result vegf level differ group p lower patient acut csc p chronic csc p control pedf level similar group vegf pedf ratio lower csc patient control p negat correl diseas durat note pedf level group chronic csc rho p discuss studi confirm patient csc imbalanc level vegf pedf find may import implic pathogenesi csc vegf independ arteriogenesi rather angiogenesi may underli vascular abnorm patient | D056833;D042461 | T116;T047;T123 |
34,684,099 | ent resid benefit structur oper plan approach train function endoscop sinus surgeri background object preoper plan util comput tomographi ct utmost import function endoscop sinus surgeri fess frequent uniform document plan structur avail resid train consequ overal complet qualiti oper plan may vari great object present studi evalu impact structur oper plan sop approach report qualiti user conveni day sinus surgeri cours materi method fifteen particip request plan fess procedur base ct scan paranas sinus exhibit common patholog featur convent manner use free text afterward particip reevalu scan mean specif design structur report templat two experienc ent surgeon assess collect convent oper plan cop sop method independ regard time requir overal qualiti legibl user conveni data collect util visual analogu scale result signific greater time expenditur associ sop vs p yet legibl vs p overal complet vs p sop signific superior cop addit descript high relev variant anatomi patholog outlin greater detail user conveni data delin signific prefer sop vas vs p conclus ct base plan fess procedur resid train use structur approach time consum produc superior report qualiti term detailed readabl consequ sop consid valuabl tool process preoper evalu especi within resid | D007396;D010256 | T097;T065;T023;T030 |
34,684,098 | bullous pemphigoid pemphigoid dermatos pemphigoid famili dermatos character autoimmun subepiderm blister classic paradigm pemphigoid common member bullous pemphigoid variabl clinic present without frank bulla link signific pruritus afflict elder mucous membran pemphigoid umbrella term group subepiderm blister dermatos favor mucos membran scar epidermolysi bullosa acquisita chronic blister disord character skin fragil sensit trauma treatment refractori natur clinician encount pemphigoid disord may benefit overview clinic present diagnost work therapeut manag emphasi frequent encount pemphigoid diseas bullous pemphigoid | D010391;D012872 | T047 |
34,684,097 | ten reduc intens acut chronic pain comprehens apprais characterist outcom review meta analys background object uncertainti clinic efficaci transcutan electr nerv stimul ten allevi pain span half centuri attempt synthesis entir bodi systemat review evid aim comprehens review critic apprais characterist outcom systemat review evalu clinic efficaci ten type acut chronic pain adult materi method search electron databas full report systemat review studi overview systemat review hybrid review evalu efficaci ten type clinic pain adult screen report elig criteria extract data relat characterist outcom review includ effect size estim conduct descript analysi extract data result includ review consist eight overview seven hybrid review systemat review meta analys talli author conclus found tendenc toward benefit ten review benefit review inconclus evid review three meta analys pool suffici data confid effect size estim ie pool analysi event lower pain intens found ten compar control chronic musculoskelet pain labour pain lower analges consumpt found post surgeri ten apprais reveal repeat shortcom rcts hinder confid judgement efficaci result stagnat evid conclus apprais reveal exampl meta analys suffici data demonstr benefit exampl meta analys suffici data demonstr benefit therefor recommend ten consid treatment option consider quantiti review insuffici data meaningless find cloud issu efficaci offer solut issu go forward | D059350;D004561 | T047;T184;T061 |
34,684,096 | sequenti pbm saffron treatment anim model retin degener background object saffron treatment photobiomodul pbm non invas therapeut approach abl mitig stabil retin degen diseas age relat macular degener amd although differ therapi partial match modul pattern gene recent attempt find addit effect coadministr saffron pbm fail instead studi differ protocol increas neuroprotect provid consecut saffron pbm treatment administr suggest materi method albino rat whose retin damag caus light exposur ld light damag subject differenti treatment protocol ld pbm follow saffron singl treatment pbm thin photoreceptor layer neuro inflammatori marker gliosi microglia assess via immun histochem techniqu result result confirm pbm saffron alon cope retin neurodegen process preserv retin thick gliosi microglia invas differenti way howev synergist effect combin treatment restrict earli neuroinflamm even provid sequenti conclus broad spectra action neuroprotect requir investig identifi key pathway help enhanc effect two approach combin | D027622;D008268;D012162 | T047;T002;T046 |
34,684,095 | molecular dock dynam simul reveal ivermectin potenti drug schistosoma associ bladder cancer target protein signal comput drug reposit approach urogenit schistosomiasi caus schistosoma haematobium nbsp haematobium infect link develop bladder cancer studi three repurpos drug ivermectin arteeth praziquantel screen find potent drug repurpos candid schistosoma associ bladder cancer sabc human use comput method biolog glutathion transferas gsts protein vascular endotheli growth factor vegf complex multifacet accord recent evid protein activ particip mani tumorigen process cell prolifer cell surviv drug resist vegf gsts wide acknowledg import target antitumor therapi thus present studi ivermectin display promis inhibit bladder cancer cell via target vegf gsts signal moreov molecular dock molecular dynam md simul analysi reveal ivermectin effici target bind pocket vegf receptor protein possess stabl dynam behavior bind site therefor propos compound must test experiment vegf gst signal order control sabc studi lie within idea discov repurpos drug inhibitor differ type human cancer target essenti pathway order acceler drug develop cycl | D004364;D001749 | T191;T121 |
34,684,094 | non alcohol fatti liver diseas covid two pandem hit time covid pandem still global burden case report far although main affect respiratori organ covid mani extrapulmonari manifest includ among thing liver injuri mani hypothes propos explain direct indirect impact sar cov virus liver studi shown around patient covid under liver diseas patient covid alter liver enzym admiss one hypothes reactiv under liver diseas non alcohol fatti liver diseas nafld studi shown nafld associ sever covid poor outcom nevertheless studi show signific differ group compar complic clinic outcom patient nafld may suffer sever covid due comorbid especi cardiovascular diseas link nafld covid clear yet studi research need | D000086382;D065626 | T047;T067 |
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