PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,674,942 | transfer one embryo simultan justifi patient elect singl embryo transfer eset first introduc ivf subsequ integr mainstream reproduct endocrinolog infertil huge consequenti view first among mani sinc add on ivf signific advers affect ivf practis result astonish declin live birth rate fresh non donor ivf cycl worldwid propos like add on ivf recent year almost univers use eset worldwid lack proper valid under hypothesi base statist incorrect assumpt incorrect data interpret recent add on ivf eset lack evidentiari support therefor remark success marketplac must base expert opinion lowest level evid medicin wide recogn frequent bias like add on ivf eset practic must reassess offer benefit wide claim provid prolong time concept advers affect live birth chanc mani women moreov ignor infertil women valu quick concept consider provid insist eset frequent depriv right self determin | D007247 | T033;T047;T046 |
34,674,940 | target cancer treatment fertil effect immunotherapi small molecul inhibitor femal reproduct target cancer therapi rapid evolv landscap person health care novel approach select imped tumour growth carri signific potenti improv surviv outcom particular reproduct age patient harbour treatment refractori diseas current agent fall within two class immunotherapi small molecul inhibitor collect divid follow subclass monoclon antibodi immunomodul adopt cell therapi treatment vaccin kinas inhibitor proteasom inhibitor metalloproteinas heat shock protein inhibitor promot apoptosi short long term effect treatment femal reproduct system well understood result clinician render unabl appropri counsel women downstream effect fertil data driven consensus recommend desper need review aim character effect target cancer therapi femal hypothalam pituitari ovari axi direct ovarian function concept | D007167;D009369 | T191;T061 |
34,674,938 | pronat weightbear radiograph correl pronat weightbear ct scan hallux valgus hv first metatars pronat increas recogn import aspect deform purpos studi compar pronat hv patient determin shape later head first metatars ap weightbear radiograph pronat calcul weightbear ct wbct scan | D000071378;D006215;D008682 | T190;T023;T020 |
34,674,937 | clinic result keck kelli wedg osteotomi approach haglund deform minimum year follow haglund deform may difficult treat non surgic caus promin bone hump posterosuperior region calcaneus may associ bursiti foot pain mani surgic treatment resist haglund deform describ evalu aofa score pain characterist patient undergo remov dorsal base wedg posterior calcaneus keck kelli procedur | D000125;D002062;D002111 | T047;T023 |
34,674,936 | pre clinic vitro model vascular graft coat prevent vascular graft infect systemat review vascular graft infect vgi fear complic prevent utmost import vascular graft coat vgcs could offer potenti vitro research first crucial step aim studi summaris key featur vitro model investig coat strategi prevent vgi order provid guidanc setup futur translat research | D001807;D011474 | T058;T074 |
34,674,935 | systemat review critic apprais peri procedur tissu perfus techniqu clinic valu patient peripher arteri diseas mani techniqu introduc enabl quantif tissu perfus patient peripher arteri diseas pad current none techniqu wide use analys real time tissu perfus chang endovascular surgic revascularis procedur aim systemat review provid date overview peri procedur applic current avail techniqu diagnost accuraci assess tissu perfus relationship clinic outcom | D003935;D055420 | T060 |
34,674,934 | mechan behaviour fenestr current aortic endograft aim studi assess mechan characterist current commerci avail fenestr endograft fe perform fenestr accord design compar relationship bridg cover stent graft csg fenestr | D001807;D015607 | T074 |
34,674,929 | independ cumul effect recent maltreat suicid ideat thought self harm nation sampl youth studi examin impact sever form past year maltreat thought self harm suicid ideat consid effect may vari gender | D002649;D019548;D017579;D016728 | T098;T055;T048;T068;T054 |
34,674,926 | character mutant type vii collagen under inversa subtyp recess dystroph epidermolysi bullosa patient recess dystroph epidermolysi bullosa rdeb lack function type vii collagen c lead skin fragil bulla eros wound rdeb inversa rdeb subset rdeb character lesion local bodi area higher skin temperatur flexur skin fold | D013696 | T081 |
34,674,925 | oncostatin sensit keratinocyt uvb induc inflamm via gsdme mediat pyroptosi oncostatin osm interleukin il famili proinflammatori cytokin play critic role inflammatori skin diseas mechan action well understood | D014466 | T070 |
34,674,923 | evalu multiparametr shear wave elastographi indic malign benign breast lesion evalu shear wave elastographi indic multiparametr swe breast lesion base patient lesion depend featur assess contribut differ elastograph paramet radiolog diagnosi | D001943;D054459 | T191;T060 |
34,674,922 | app teach resid communic diagnost uncertainti mobil game applic clear communic integr good clinic care howev communic train cost time intens mobil applic app may provid use adjunct tradit simul skill train | D007396;D063731;D018910 | T097;T065;T170;T073 |
34,674,921 | develop audio base communic tool nicu discharg latino famili limit english profici research show nicu latino parent limit english profici lep feel less comfort ask question particip medic decis make may negat affect transit communiti healthcar question prompt list qpl suggest question sometim drawn famili provid improv famili center communic explor clinician parent percept inform develop pilot nicu discharg qpl | D000080031;D010351 | T058;T033 |
34,674,918 | function outcom submandibular gland spare neck dissect patient oral squamous cell carcinoma feasibl submandibular gland smg preserv neck dissect describ aim studi analys function outcom patient undergo smg preserv neck dissect ct n oral squamous cell carcinoma consecut patient divid two group base manag smg underw saliva flow test surgeri day surgeri month surgeri enrol patient complet fourth version univers washington qualiti life uwqol questionnair month surgeri patient underw smg preserv neck dissect flow rate day surgeri signific lower preoper howev gradual return baselin month surgeri saliva flow rate month surgeri similar month surgeri patient smg preserv higher score activ swallow chew saliva domain patient without smg preserv result studi suggest saliva secret abil preserv follow smg spare neck dissect smg preserv improv postop qualiti life | D002294;D006258;D009062 | T191 |
34,674,917 | prognost valu exercis induc pulmonari hypertens asymptomat patient primari mitral regurgit examin whether earli develop exercis induc pulmonari hypertens eiph right ventricular dysfunct exercis stress echocardiographi ese may predict clinic deterior call asymptomat patient primari least moder mitral regurgit mr | D006976;D008944 | T047;T046 |
34,674,916 | kihon checklist use predict outcom patient undergo transcathet aortic valv implant frailti major risk factor death disabl follow transcathet aortic valv implant tavi kihon checklist kcl simpl self report yesno survey consist question use screen tool identifi frailti primari care set clinic studi focus frailti calcul kcl tavi cohort investig year prognost impact frailti evalu kcl patient underw tavi | D001024;D000073496;D065467 | T047;T184;T046;T061;T033 |
34,674,915 | feed foot nutrit influenc equin hoof health nutrit play import role equin health includ foot defici excess dietari compon affect growth function foot associ import podiatr diseas recognit prevent treatment specif notabl nutrit diseas foot discuss well inform regard specif ingredi includ supplement meant improv equin hoof qualiti ensur provis balanc diet maintain hors appropri bodi condit seek guidanc equin nutritionist creat dietari recommend prevent equin foot diseas relat nutrit | D005534;D006724;D006734 | T023;T047 |
34,674,914 | support limb lamin support limb lamin sll relat frequent complic pain limb condit alter normal weight bear pattern hors new evid suggest lack limb load cycl activ normal associ ambul interfer normal perfus lamella case result ischemia dysfunctiondeath cell critic mechan function lamella excess weight bear load drive progress overt acut lamin support limb monitor enhanc limb load cycl activ key strategi may lead success prevent sll ensur adequ lamellar perfus | D005534;D006724;D006734 | T023;T047 |
34,674,912 | imag equin foot past year advanc diagnost imag technolog led improv radiograph techniqu develop stand comput tomographi ct pet ct scanner although modal initi stage develop clinic applic meant revolution diagnosi manag diseas foot stand patient particular detect subclin lesion establish comput assist surgic suit articl also review improv radiograph project equin foot benefit high field contrast magnet reson imag mri diagnosi cartilag ligament patholog | D006734;D000072078 | T047;T060 |
34,674,911 | pharmacolog equin foot medic pain manag lamin one biggest challeng manag lamin hors remain control pain best analges approach multimod approach includ nonsteroid anti inflammatori drug opioid andor constant rate infus agonist ketamin lidocain recent literatur indic amitriptylin solubl epoxid hydrolas inhibitor might benefici clinic orient studi need place lamin pain manag system pain control combin local techniqu long act local anesthet epidur catheter allow administr potent analges therapi lower risk negat side effect | D006734;D059408 | T047;T061 |
34,674,910 | anatomi physiolog equin foot articl provid overview foot anatomi physiolog focus fundament knowledg foot defin epiderm hoof capsul structur envelop capsul anatomi describ use terminolog publish nomina anatomica veterinaria | D006724;D006734 | T047;T023 |
34,674,909 | big pictur better understand equin foot multipl topic summar articl discuss detail issu vcna comprehens depth explor concept clinic experi state art care equin foot research equin foot translat clinic set compassion care hors | D005534;D006734 | T047 |
34,674,908 | endocrinopath lamin endocrinopath lamin el primarili occur insulin dysregul id mediat downstream effect insulin igf r lamellar tissu like contribut vascular metabol dysfunct within lamella el relat non inflammatori el associ lamellar stretch prolifer failur ultim caus failur suspensori apparatus distal phalanx proper educ regard mitig risk factor make larg prevent caus lamin annual hoof evalu plus screen geriatr hors pituitari par intermedia dysfunct id younger hors id signific decreas incid devast condit | D004700;D005534;D006724;D006734;D010900 | T023;T047 |
34,674,907 | independ effect viscer fat left atrial phasic function general popul obes increas risk atrial fibril af although impact abdomin fat distribut left atrial la morpholog function remodel remain unclear studi aim investig whether increas abdomin adipos independ associ impair la function andor la enlarg sampl general popul evalu role adipokin associ | D016279;D050152 | T024;T042 |
34,674,906 | cost incur nhs england due unnecessari prescrib depend form medic cross section studi estim cost incur nation health servic nhs england consequ unnecessari prescrib ie non indic dispens depend form medicin antidepress opioid gabapentinoid benzodiazepin z drug assess prescrib primari care april march analys base upon follow data set number adult continu prescrib depend form medic durat prescript obtain public health england net ingredi cost nic dispens cost medicin obtain nhs busi servic author nhsbsa consult cost calcul base guidelin recommend number consult evidenc prior research long term medic monitor across opioid gabapentinoid benzodiazepin z drug total estim unnecessari cost three year april march antidepress total estim unnecessari cost one year data indic nhs england may incur signific estim mean annual loss opioid gabapentinoid benzodiazepin z drug estim annual loss antidepress combin give estim annual loss result non indic dispens prescrib depend form medicin estim conserv figur could higher | D004364;D013222 | T121;T064 |
34,674,905 | home cannabi smoke preval home tobacco smoke among global drug survey respond earli evid studi home smoke polici suggest home cannabi smoke often allow home tobacco smoke yet data whether cannabi often smoke home compar tobacco whether home cannabi tobacco smoke differ usag status use cross section data sentinel drug user countri compar cannabi tobacco smoke home global drug survey respond current use cannabi tobacco tobacco cannabi neither | D008385;D004364 | T121;T055 |
34,674,904 | analysi sever cutan advers reaction scar taiwan drug injuri relief system year result taiwan drug injuri relief system tdrs implement sinc approv applic associ sever cutan advers reaction scar studi assess scar use real world evid limit tdrs offer abund case inform sourc real world evid investig characterist scar taiwan purpos studi understand trend characterist scar taiwan | D010672;D013262 | T047;T121;T109 |
34,674,903 | suicid trend vari age subgroup covid pandem taiwan outbreak coronavirus diseas covid led unpreced impact mental health global recent empir data howev indic suicid rate mani countri remain unchang even decreas exist studi assess overal rate stratifi age subgroup | D000086382;D013405 | T033;T047;T067 |
34,674,902 | preval diabet mellitus carotid atherosclerosi relationship middl age adult elder communiti base studi atherosclerosi diabet mellitus dm sever chronic diseas caus huge burden patient famili societi connect two diseas brought high attent recent howev popul base studi larg sampl size studi aim explor relationship carotid atherosclerosi dm | D050197;D002340;D003920;D058226 | T047;T031;T020;T046 |
34,674,901 | differ inpati insert cardiac monitor placement ischem stroke cryptogen stroke account ischem stroke patient cardiac monitor lead increas detect af increas util anticoagul decreas risk recurr stroke aim identifi differ inpati util implant cardiac monitor icm patient ischem stroke | D015716;D054625;D000083242 | T080;T047;T060 |
34,674,899 | comminut dorsal ulnar fragment distal radius fractur treat use integr compress screw mini plate stabil displac dorsoulnar fragment distal radius fractur challeng treat convent volar lock plate alon integr compress screw combin volar lock plate introduc addit tool stabil dorsoulnar fragment report work effect howev compress screw unabl stabil comminut dorsal ulnar fragment therefor necessari consid use addit dorsal plate develop modifi surgic techniqu stabil comminut dorsal intra articular fragment combin integr compress screw mini plate washer buttress | D018460;D011885 | T037 |
34,674,896 | clinic function efficaci gallium arsenid super puls laser therapi temporo mandibular joint pain orofaci myalgia follow heal unilater cervicofaci burn random trial cervicofaci burn cb uniqu type burn involv later part face neck chest region signific skin contractur temporomandibular joint tj pain orofaci myalgia om major problem physiotherapi context treat laser common use adjunct therapi pain condit howev clinic studi lack investig effect gallium arsenid ga super puls laser therapi temporomandibular joint pain orofaci myalgia follow heal cervicofaci burn patient | D002056;D005708;D013705 | T047;T196;T037 |
34,674,895 | complic ankl arthrodesi diabet relat charcot foot syndrom charcot neuroarthropathi cn inflammatori arthropathi associ boni destruct disloc deform patient neuropathi surgic procedur involv foot ankl cn deform correct shown result high rate complic purpos studi compar post oper outcom assess odd complic ankl arthrodesi among patient diabet relat charcot neuroarthropathi non charcot patient diabet non charcot patient without diabet | D001177;D048909;D017719 | T047 |
34,674,894 | thymic hyperplasia studi case thymic hyperplasia present anterior mediastin mass pose import diagnost therapeut challeng two type thymic hyperplasia describ true hyperplasia follicular hyperplasi literatur data peculiar concern entiti aim describ clinic microscop characterist thymic hyperplasia singl institut experi year period | D008206;D008477;D013952 | T047 |
34,674,893 | feasibl age gestat base routin univers influenza vaccin schedul children age month year pregnant women hong kong season influenza schedul follow world health organ northern hemispher vaccin composit recommend year round influenza activ potenti implement routin age gestat base schedul utilis northern southern hemispher vaccin children age month year pregnant women studi assess potenti feasibl schedul | D007252;D007251 | T129;T047;T121;T109 |
34,674,892 | prognost indic outcom follow surgic manag metastat cutan squamous cell carcinoma head neck metastat cutan scc carri poor prognosi five year surviv aim studi examin outcom follow surgeri adjuv therapi manag metastat cscc uk base popul retrospect review patient metastat cscc head neck underw primari surgeri region center six year period overal diseas specif surviv calcul use kaplan meier log rank test result report hazard ratio hr confid interv forti five patient met inclus criteria mean time discoveri metastas month rang month two patient discoveri metastas two year none year overal five year surviv ci two year surviv ci median os surviv day ci patient age year decreas os largest uk base studi document overal diseas specif surviv associ metastat cutan scc head neck overal surviv compar similar studi remain poor total number involv node lymph node ratio statist signific | D002294;D006258;D012878 | T191 |
34,674,891 | retin ganglion cell distribut spatial resolut asiat toad bufo gargarizan gnther vision play crucial role biolog anuran spatial arrang retin ganglion cell gcs close relat visual behavior vertebr scarc data gc topographi anuran particular toad studi number distribut gcs retina asiat toad bufo gargarizan gcs uneven distribut across retina spatial densiti minimum dorsal peripheri cellsmm smaller larger toad respect increas toward retin equat moder pronounc visual streak observ compris sever patch greater gc densiti streak somewhat vagu dorsal ventral border maximum gc densiti cellsmm smaller larger toad respect found tempor retina slight dorsal equat respect zone identifi area centrali total gc number rang smaller toad cell larger toad spatial resolut estim eye geometri gc densiti air minimum dorsal peripheri cycl per degre smaller larger toad respect maximum area centrali cycl per degre smaller larger toad respect retin special found asiat toad match biolog | D012160;D012165 | T025;T023 |
34,674,888 | comparison speech percept list use evalu japanes singl syllabl hear japan singl syllabl list use test speech percept cochlear implant ci user howev due advanc implant processor list becom simpl ci user japan otolog societi creat new list refer ici object studi compar perform list | D019929;D003054;D013067 | T074;T041;T061 |
34,674,887 | vestibular function patient idiopath sudden sensorineur hear loss relat prognosi anatom close relationship cochlea vestibular organ cochlear function disord may accompani vestibular disord studi aim evalu vestibular function patient idiopath sudden sensorineur hear loss use vemp calor test vng test batteri relat prognosi | D015834;D003638;D006319;D003639;D014012;D058585 | T034;T047;T184;T037;T033 |
34,674,886 | acid sens ion channel potenti therapeut target tissu acidif associ varieti diseas state acid sens ion channel asic sens chang ph gain traction possibl pharmaceut target array modul rang small molecul larg biopharmaceut known inhibit asic summar recent insight anim studi assess therapeut potenti asic disord ischem stroke various pain relat process anxieti cardiac patholog also review factor present challeng pharmacolog target asic need taken care consider develop potent select modul futur | D062565 | T116;T123 |
34,674,885 | shear elast coeffici normal fibrinogen defici clot plasma obtain sphere motion base acoust radiat forc approach blood coagul process involv sever chemic reaction govern coagul factor shear elast coeffici vari medium transit liquid gel phase work use ultrasound measur clot human plasma sampl track motion glass sphere locat insid cuvett fill plasma mhz ultrason system generat impuls acoust radiat forc act sphere mhz puls echo ultrason system track sphere displac induc forc measur determin fit depend theoret model motion waveform sphere immers clot normal plasma plasma sampl fibrinogen fi concentr fi defici fi normal gl normal plasma start pa increas rapid min slowli reach pa min clot process start similar trend exhibit plasma sampl fi concentr gl reach pa respect theoret model relat kinet clot structur format describ time chang clot plasma sampl sphere motion base acoust radiat forc approach allow us measur shear elast coeffici coagul process plasma sampl normal defici fi concentr result suggest method use studi capabl use detect bleed disord | D005340;D006490 | T116;T121;T123 |
34,674,882 | alter nucleocytoplasm transport heart transplant reject nucleocytoplasm transport crucial process cell function previous studi observ alter differ molecul involv relat ventricular function howev publish data evalu possibl differ express molecul heart transplant ht recipi object evalu whether level relat appear cellular reject cr first year ht | D006331;D016027 | T047;T061 |
34,674,881 | influenc donor recipi sex match simultan pancrea kidney transplant outcom sever studi solid organ transplant shown correl donor recipi sex mismatch risk graft loss howev possibl influenc well establish aim studi review outcom pancreat kidney graft seri depend sex match | D016030;D016035 | T061 |
34,674,880 | wean mechan ventil neurocrit care intens care unit icu wean mechan ventil follow step step process well establish general icu popul howev littl data avail brain injuri patient often intub protect airway prevent central hypoventil narrat review describ general principl wean principl adapt brain injuri patient focus three major issu regard wean mechan ventil brain injuri patient sedat protocol wean extub protocol criteria criteria time techniqu tracheostomi | D001930;D012121 | T061;T037 |
34,674,879 | neurofeedback cognit enhanc intervent brain plastic recent year neurofeedback use cognit train tool improv brain function clinic recreat purpos base provid particip feedback brain activ train control initi direct chang overarch hypothesi behind method control result enhanc cognit abil associ brain activ trigger specif structur function chang brain promot learn neuron plastic effect review general methodolog principl behind neurofeedback describ behaviour benefit clinic experiment context review non specif effect neurofeedback reinforc learn striato frontal network well specif chang cortic network neurofeedback control exert last analys current challeng face neurofeedback studi includ quantif tempor dynam neurofeedback effect generalis behaviour outcom everyday life situat design appropri control disambigu placebo true neurofeedback effect develop advanc cortic signal process achiev finer grain real time model cognit function | D058765 | T061;T041 |
34,674,877 | untangl relationship microglia tau alzheim diseas autopsi imag studi demonstr typic pattern tau progress alzheim diseas ad spread previous unaffect region anatom sequenc braak stage recent studi pascoal et al provid evid microgliosi coloc tau braak like pattern further notion microgli activ strong relat propag tangl patholog | D000544;D017628 | T025;T048;T047 |
34,674,876 | erector spina muscl radiograph densiti associ surviv lung transplant studi object verifi whether low preoper radiograph densiti erector spina muscl associ poor prognosi lung transplant | D008168;D016040 | T023;T061 |
34,674,875 | chronic diarrhea parasit infect diagnost challeng diarrhea among top ten global caus death chronic diarrhea may destruct impact physic mental health patient also associ high risk mortal children parasit intestin infect remain import caus chronic diarrhea especi develop part world | D007411 | T047 |
34,674,874 | compar analysi differ method use molecular character burkholderia cepacia complex isol noncyst fibrosi condit burkholderia gram negat opportunist bacterium capabl caus sever nosocomi infect aim studi character burkholderia cepacia complex compar differ molecular method use character | D019121;D016956;D042602 | T007;T047 |
34,674,867 | clinic outcom follow isol transcathet tricuspid valv repair meta analysi meta regress studi aim studi assess pool clinic echocardiograph outcom differ isol transcathet tricuspid valv repair ittvr strategi signific moder greater tricuspid regurgit tr | D019918;D014262 | T047;T061 |
34,674,865 | impact transcathet mitral valv repair preprocedur postprocedur hospit rate object studi determin effect transcathet mitral valv repair tmvr hospit rate assess pre postprocedur hospit pattern | D006333;D019918;D008944 | T047;T061;T046 |
34,674,862 | right ventricular pulmonari arteri coupl patient hf secondari mr analysi coapt trial aim studi determin prognost impact right ventricular rv pulmonari arteri pa coupl patient heart failur hf sever secondari mitral regurgit smr enrol coapt cardiovascular outcom assess mitraclip percutan therapi heart failur patient function mitral regurgit trial | D006333;D006976;D008944 | T047;T046 |
34,674,861 | art sapien transcathet mitral valv replac valv ring valv mitral annular calcif procedur sapien transcathet heart valv commerci avail compassion transcathet mitral valv replac patient previous mitral surgic ring mitral annular calcif valv ring vir valv mitral annular calcif vim report outcom inconsist poor review provid overview author approach achiev larg consist result despit intrins limit sapien vim vir approach includ bedsid modif valv implant deliveri system cardiac substrat purpos built devic readili avail vir vim procedur requir aggress multidisciplinari cooper meticul plan execut postprocedur manag experienc high volum oper | D006350;D019918 | T074;T061 |
34,674,859 | preval thrombosi patient cancer sar cov infect covid infect cancer associ increas risk thrombot event aim studi analyz cumul incid thrombosi oncolog patient covid detect differ non cancer covid popul | D000086382;D009369;D013927 | T191;T047;T046;T067 |
34,674,855 | matern preconcept occup exposur clean product disinfect offspr asthma emerg research suggest health effect offspr parent chemic exposur concept mani futur mother expos potent chemic work potenti offspr health effect hard investig | D003902;D004202;D018811;D016273 | T121;T073;T167;T131;T037;T120 |
34,674,853 | parkinson cerebrospin fluid disord although various motor manifest seen patient cerebrospin fluid csf disord hydrocephalus intracrani hypotens clinic present parkinson clear elucid | D006850;D020734 | T047;T050 |
34,674,852 | histor perspect glanc antibodi base condit regimen new era horizon hematopoiet cell transplant practic chang signific year center around globe offer transplant differ type diseas growth driven improv efficaci safeti procedur abil use altern donor improv made procedur feasibl virtual patient need avail novel therapi target agent may wit new transplant era agent may help circumv remain limit procedur open door new indic herein review histor transplant mileston accomplish led modern transplant practic discuss idea minim intens condit possibl adopt chemotherapi radiat free prepar regimen near futur | D018380;D019172 | T061 |
34,674,848 | virtual interview util technolog afford predictor applic confid midst pandem resid interview transit virtual format first time littl known effect match process studi aim evalu resid applic process perceiv outcom | D012570;D012649;D014584 | T065;T170;T080;T041 |
34,674,847 | use artifici intellig gender bias analysi letter recommend general surgeri resid candid letter recommend lor play import role resid select author languag vari implicit toward male femal applic examin gender bias lor written surgic resid candid across three decad one institut | D001185;D063507 | T054;T066;T073;T090 |
34,674,845 | result use method full extraperiton endoscop assist ligat hernial sac inguin hernia children aim studi evalu effect new techniqu inguin hernia repair children pediatr hernia extra periton ligat percutan sutur phelp comparison anoth laparoscop techniqu subcutan endoscop assist ligat seal | D006552;D010535;D006848 | T047;T190;T019;T061;T060 |
34,674,843 | time deconstruct treatment failur random control trial nonop manag uncompl pediatr append antibiot alon publish data demonstr manag uncompl pediatr append antibiot alon safe frequent success random control trial rct compar antibiot alon appendectomi lack alongsid insight driver failur sought valid antibiot alon approach identifi barrier success use rct design | D001064 | T047 |
34,674,841 | artifact express polyetheretherketon cone beam comput tomographi vitro studi dental prosthet materi caus artifact cone beam comput tomographi cbct imag advers affect diagnost qualiti although problem may less polyetheretherketon peek studi evalu artifact caus frequent use prosthet materi lack | D016477;D054893 | T060;T068 |
34,674,835 | establish qualiti indic pre hospit advanc airway manag modifi nomin group techniqu consensus process pre hospit advanc airway manag complex intervent compos numer step interact variabl deliv high standard pre hospit set standard research method struggl evalu complex intervent consider heterogen patient provid techniqu studi aim develop set qualiti indic evalu pre hospit advanc airway manag | D019984 | T080;T081 |
34,674,834 | lower versus higher oxygen target critic ill patient sever hypoxaemia secondari bayesian analysi explor heterogen treatment effect handl oxygen target intens care unit hot icu trial handl oxygen target intens care unit hot icu trial lower kpa vs higher kpa pao target affect mortal amongst critic ill adult patient use bayesian statist evalu heterogen effect oxygen target mortal differ patient group within hot icu trial | D007362 | T093;T073 |
34,674,830 | common practic among consist high perform vitro fertil program unit state year updat evalu similar differ clinic laboratori practic among high perform fertil clinic | D005307;D018873 | T010;T061;T081 |
34,674,828 | testicular sperm characterist men nonobstruct azoospermia impact intracytoplasm sperm inject outcom report fertil clinic pregnanc rate base sperm characterist time intracytoplasm sperm inject icsi men nonobstruct azoospermia noa follow microdissect testicular sperm extract mtese | D053625 | T058;T061 |
34,674,826 | fertil health inform seek among sexual minor women qualit explor describ fertil inform seek experi sexual minor women smw coupl use assist reproduct | D054626;D005298;D007722;D054525;D010342;D034121 | T089;T055;T170;T071;T032;T058;T053;T040;T033;T062;T080 |
34,674,825 | review pathophysiolog recurr implant failur implant critic step human reproduct success step depend compet blastocyst recept endometrium success cross talk embryon matern interfac recurr implant failur lack implant transfer sever embryo transfer success vitro fertil increas failur becom unaccept patient provid literatur recurr implant failur increas clinic phenomenon often encount univers agre definit someth address earlier portion view review implant failur result sever differ factor review discuss factor includ matern immun system genet embryo parent anatom factor hematolog factor reproduct tract microbiom endocrin milieu factor embryo endometri synchroni potenti caus various stage research clear implic immedi appar treatment | D017211 | T033 |
34,674,824 | predict person cumul live birth follow vitro fertil develop vitro fertil ivf predict model estim individu chanc cumul live birth two time point pretreat ie start first complet cycl ivf posttreat ie start second complet cycl ivf coupl whose first complet cycl unsuccess | D003661;D005307 | T061;T170;T010;T090 |
34,674,817 | burnout well among cardiolog fellowship program director third annual cardiovascular diseas cv fellowship program director pds survey sought understand burnout well among cv fellowship pds | D002055;D000077062;D000072096;D008486 | T097;T048 |
34,674,815 | improv longitudin outcom effici equiti care patient congenit heart diseas longitudin follow resourc util health dispar top congenit heart research care prioriti medicaid claim includ longitudin data inpati outpati emerg pharmaci rehabilit home health util social determin health includ mother infant pair | D000069576 | T080 |
34,674,813 | associ genet variant outcom patient nonischem dilat cardiomyopathi clinic relev genet variant nonischem dilat cardiomyopathi dcm unsettl | D014644 | T070 |
34,674,811 | contribut systol diastol blood pressur cardiovascular outcom allhat studi sbp dbp import associ cardiovascular event seldom consid simultan | D001794;D003971;D013599 | T040;T042;T079;T201 |
34,674,808 | menopaus women schizophrenia schizoaffect disord bipolar disord transit menopaus usual occur age time women particular vulner preexist mental ill present symptom often amplifi period moreov women mental ill experi menopaus symptom similar healthi women narrat review summar current data regard menopaus women schizophrenia schizoaffect disord bipolar disord well current standard manag care manag chronic diseas women suffer sever mental ill also consid | D001714;D011618;D012559 | T048 |
34,674,807 | menopaus cardiometabol diseas nt know matter narrat review discuss current understand knowledg gap challeng expand knowledg associ menopaus reproduct age process cardiometabol diseas cmd women focus type diabet cardiovascular diseas physiolog chang occur differ stage reproduct life span well type menopaus time factor wide associ cmd risk howev under mechan remain either unclear insuffici studi decreas ovarian estrogen product relat androgen excess around menopaus onset studi factor link menopaus cardiometabol health nevertheless evid persuas hypothes might explain chang cmd risk menopaus transit context hormon therapi wide adopt treatment prevent cmd although uncertainti regard cardiometabol effect rais need optim therapeut modal mechan iron overload theori new omic platform could provid new insight potenti pathway under associ menopaus cardiometabol health dna damag respons although wide report environment lifestyl factor affect menopaus cardiometabol health littl evid role exposur menopaus associ cmd risk | D002318;D003924 | T047 |
34,674,806 | motiv strategi improv adher physic activ breast cancer survivor systemat review meta analysi two behavior chang base strategi promot adher physic activ pa suggest greatest potenti pedomet motiv interview mi howev comparison two strategi identifi one effect improv pa adher systemat review meta analysi aim determin pa motiv strategi effect promot adher self direct pa femal breast cancer survivor studi implement self direct pa use step tracker andor mi motiv femal breast cancer survivor identifi follow databas two timepoint septemb june central pubm cinahl psycinfo sportdiscuss sixteen random control trial rcts select data extract wherea ten rcts includ meta analysi meta analysi perform pool data estim standard mean differ pa durat step count confid interv number particip meet pa recommend also analyz subgroup analysi perform three motiv strategi pedomet combin counsel print materi motiv interview meta analysi show pedomet combin anoth intervent small effect step count p moder effect durat moder vigor physic activ mvpa p compar control addit motiv strategi increas number particip meet pa goal p find review endors use step tracker combin counsel print materi mi base behavior chang theori approach provid consist posit effect adher self direct pa among breast cancer survivor futur studi evalu differ measur adher self direct pa identifi best motiv strategi improv patient adher health outcom systemat review registr prospero registr number crd | D000072936;D062405 | T061;T073 |
34,674,805 | frailti ethnic minor women major popul high middl incom countri women live longer yet experi higher level frailti men age unclear whether sex frailti paradox present ethnic minor popul narrat review explor biolog behaviour social factor associ mortal morbid frailti women particular ethnic minor women ascertain natur menopaus occur earlier women particular ethnic ethnic minor women live high incom countri children higher rate chronic diseas disabl associ frailti ethnic minor women less like engag deleteri health behaviour smoke alcohol consumpt howev other revers true women migrant ethnic minor tend lower level physic activ time also adopt advers behaviour pattern major popul although evid spars sex differ health report social asset well gender role like contribut sex differ frailti ethnic minor overal ethnic minor women particular vulner group major risk factor frailti appear mutabl rather fix futur research may examin intervent target frailti differ race ethnic individu popul global level | D015444;D008913 | T061;T098;T056 |
34,674,804 | variant clock gene could associ lower risk type diabet elder greek popul recent evid link circadian rhythm dysregul increas risk metabol disord studi explor potenti associ variat gene regul endogen circadian time system clock gene risk type diabet td sampl greek elder peopl | D027682;D057906 | T040;T116;T123 |
34,674,803 | cross section longitudin interact effect physic activ apo white matter integr older adult mapt studi physic activ pa shown modul detriment effect carri apolipoprotein e epsilon apo allel brain structur howev current literatur main provid cross section data longitudin studi investig interact genotyp pa white matter wm integr lack | D015444 | T061;T056 |
34,674,802 | sexual inact sexual dysfunct midlif singaporean women prospect cross section studi preval risk factor examin factor relat sexual inact sexual dysfunct midlif singaporean women | D018737 | T040;T081 |
34,674,798 | effect cisplatin mitochondri function autophagi relat protein skelet muscl rat cisplatin wide known anti cancer drug howev effect cisplatin mitochondri function autophagyrel protein level skelet muscl unclear purpos studi investig effect differ dose cisplatin mitochondri function autophagi relat protein level skelet muscl rat eight weekold male wistar rat n assign one three group first group administ salin placebo con n second third group given mgkg bodi weight bw n mgkg bw n cisplatin respect group administ mg cisplatin exhibit reduc bw skelet muscl tissu weight mitochondri function upregul level autophagi relat protein includ lcii beclin bnip moreov group high lc iii ratio skelet muscl ie administr high dose cisplatin decreas muscl mass mitochondri function increas level autophagi relat protein result thus suggest reduc mitochondri dysfunct autophagi pathway may import prevent skelet muscl atrophi follow cisplatin administr bmb report | D001343 | T043 |
34,674,797 | remodel host glycoprotein bacteri infect protein glycosyl common post translat modif found live organ modif bacteri pathogen play pivot role infecti process includ pathogen immun evas host pathogen interact import mani key protein host immun system also glycosyl bacteri pathogen notabl modul glycosyl host protein facilit pathogenesi induct abnorm host protein activ abund recent year interest studi regul host protein glycosyl caus bacteri pathogen increas fulli understand bacteri pathogenesi review focus bacteri pathogen regul remodel host glycoprotein infect promot pathogenesi bmb report | D054884;D011499 | T040;T044 |
34,674,796 | puls electromagnet field potenti etoposid induc mcf cell death etoposid chemotherapeut medic use treat various type cancer includ breast cancer establish puls electromagnet field pemf therapi enhanc effect anti cancer chemotherapeut agent studi investig whether pemf influenc anti cancer effect etoposid mcf cell determin signal pathway affect pemf observ co treatment etoposid pemf led decreas viabl cell compar cell sole treat etoposid pemf elev etoposid induc parp cleavag caspas activ enhanc etoposid induc regul survivin regul bax pemf also increas etoposideinduc activ dna damag relat molecul addit reactiv oxygen speci ros level slight elev etoposid treatment signific increas co treatment etoposid pemf moreov treatment ros scaveng restor pemf induc decreas cell viabil etoposid treat mcf cell result combin indic pemf enhanc etoposid induc cell death increas ros induct dna damag caspas depend apoptosi bmb report | D017209;D004574 | T043;T070;T116;T123 |
34,674,795 | precis control mitophagi ubiquitin proteasom system deubiquitin proteas dysfunct parkinson diseas parkinson diseas pd one common neurodegen diseas elder popul caus loss dopaminerg neuron pd predomin attribut mitochondri dysfunct structur alter synuclein trigger toxic oligom format neuron great contribut pd articl discuss role sever famili pd relat protein synuclein dj lrrk pink parkin mitophagi entail select degrad mitochondria via autophagi defect chang mitochondri dynam biochem function interact induc format toxic synucleincontain protein aggreg pd addit gene product play essenti role ubiquitin proteasom system up mediat proteolysi well mitophagi interest deubiquitin enzym dub addit modul two pathway negat posit base find summar close relationship sever dub precis modul mitophagi exampl usp usp usp among mani dub report specif regul k k link de ubiquitin reaction sever target protein associ mitophag process turn upregul mitophagi protect neuron cell synuclein deriv toxic contrast usp inhibit mitophagi oppos parkin mediat ubiquitin target protein furthermor associ chang pd pathogenesi discuss taken togeth although function role sever pd relat gene yet fulli understood substanti associ mitochondri qualiti control well up therefor better understand relationship provid valuabl therapeut clue appropri manag strategi bmb report | D063306;D010300 | T043;T047 |
34,674,794 | monoclon antibodi k base deplet pluripot cell differenti stem cell progeni prevent teratoma format human pluripot stem cell pscs util promis sourc regen medicin howev risk teratoma format come residu undifferenti pscs differenti cell popul concern clinic use psc deriv report monoclon antibodi mab target pscs could distinguish undifferenti pscs potenti teratoma form activ differenti psc progeni panel hybridoma generat mous immun h human embryon stem cell hesc screen esc specif bind use flow cytometri novel mab k select consid high stem cell bind activ mab could bind sever human induc pluripot stem cell psc line cell bind activ k mark decreas hesc differenti embryoid bodi retino acid treatment addit cell popul negat isol undifferenti differenti h hesc via k target show signific reduc express pluripot marker includ oct nanog furthermor k base deplet pluripot cell differenti psc progeni complet prevent teratoma format therefor find suggest k utiliz improv stem cell transplant safeti specif distinguish residu undifferenti pscs bmb report | D057026;D039904;D013724 | T025;T191 |
34,674,793 | neuromedin b modul phosphat induc vascular calcif vascular calcif heterotop accumul calcium phosphat salt vascular tissu high correl increas cardiovascular morbid mortal studi found express neuromedin b nmb nmb receptor upregul phosphat induc calcif vascular smooth muscl cell vsmcs silenc nmb treatment nmb receptor antagonist pd inhibit phosphat induc osteogen differenti vsmcs inhibit wnt catenin signal vsmc apoptosi pd also attenu arteri calcif cultur aortic ring rat model chronic kidney diseas result studi suggest nmb nmb receptor axi may potenti therapeut valu diagnosi treatment vascular calcif bmb report | D010012 | T042 |
34,674,791 | cost effect carbapenem resist enterobacteriacea cre surveil maryland analyz efficaci cost cost effect predict decis support system base surveil intervent reduc spread carbapenem resist enterobacteriacea cre | D000073182;D003428;D004756 | T007;T047 |
34,674,790 | associ motor plan frontopariet network children exploratori multimod studi evid adult literatur show involv cortic grey matter area frontopariet lobe white matter bundl superior longitudin fasciculus slf motor plan yet confirm children | D066127 | T023;T024 |
34,674,789 | covid patient increas age experi differenti time initi medic care sever symptom conduct retrospect observ studi patient laboratori confirm coronavirus diseas covid receiv medic care covid ambulatori unit hospit mexico citi februari decemb studi elder seek medic care later younger patient sever symptom initi medic evalu patient categoris eight group year symptom initi evalu classifi accord previous valid classif respiratori non respiratori symptom comparison time symptom onset medic care everi age categori perform varianc analys logist regress model appli determin risk present symptom sever accord age mortal risk accord delay medic care total patient includ mean age sd year women mean time symptom onset medic care sd day increas older age categori p mortal risk increas day delay medic care symptom onset risk present symptom sever greater increas age categori conclus covid patient increas age tend seek medic care later higher rate symptom sever initi present ambulatori unit hospit | D000375 | T040;T033 |
34,674,782 | emperor new markov blanket free energi principl influenti framework comput neurosci theoret neurobiolog start assumpt live system ensur adapt exchang environ minim object function variat free energi follow premis claim deliv promis integr life scienc recent work markov blanket one central construct free energi principl appli resolv debat central philosophi demarc boundari mind aim paper twofold first trace develop markov blanket start standard applic bayesian network via variat infer use literatur activ infer identifi persist confus literatur formal use markov blanket epistem tool bayesian infer novel metaphys use free energi framework demarc physic boundari agent environ consequ propos distinguish pearl blanket refer origin epistem use markov blanket friston blanket refer new metaphys construct second use distinct critic assess claim rest applic markov blanket philosoph problem suggest literatur would well differenti two differ research programm infer model infer within model latter capabl metaphys work markov blanket requir addit philosoph premis justifi appeal success mathemat framework alon | D012146 | T056 |
34,674,781 | compar risk chang needlestick injuri countri adopt adopt needlestick safeti prevent act meta analysi determin whether countri adopt needlestick safeti prevent act nspa achiev reduc risk needlestick injuri nsis | D016602 | T037 |
34,674,778 | necrotis otiti externa reduc length hospit stay complet audit cycl hospit admiss necrotis otiti externa serious condit requir hospit admiss longer hospit stay associ increas complic | D010032 | T047 |
34,674,775 | comput determin toxic risk associ select approv drug demonstr activ covid emerg rapid spread sar cov sever acut respiratori syndrom coronavirus thelat caus devast global pandem sever pneumonia like diseas coronavirus diseas covid although vaccin develop access everyon everyon receiv vaccin also typic take year new therapeut agent approv usag therefor repurpos known drug lend well key approach signific expedit develop new therapi covid | D055808;D058492 | T062;T061 |
34,674,774 | diagnost valu chest comput tomographi imag covid base revers transcript polymeras chain reaction meta analysi comput tomographi ct diagnost valu covid controversi summar valu chest ct diagnosi covid meta analysi base refer standard | D000086382;D013909;D014057 | T047;T029;T060;T067 |
34,674,770 | micronucleus product activ dna damag respons cgas sting signal syncytia induc sar cov infect sar cov infect could caus sever acut respiratori syndrom larg attribut dysregul immun activ extens lung tissu damag howev under mechan fulli understood report viral infect could induc syncytia format within cell express ace sar cov spike protein lead product micronuclei averag rate per syncytium remark micronuclei manifest high level activ dna damag respons cgas sting signal indic micronucleus transloc hax cgas upregul respect downstream target gene sinc activ signal pathway known associ cellular catastroph aberr immun activ find help explain patholog effect sar cov infect cellular molecular level provid novel potenti target covid therapi | D004249 | T049 |
34,674,764 | vivo stage region amyloid progress healthi middl age older peopl risk alzheim diseas investig region amyloid stage characterist c pib pet data middl age older particip elev risk ad enrol wisconsin registri alzheim prevent | D000544;D060825 | T048;T047 |
34,674,762 | deep learn reveal diseas specif signatur white matter patholog tauopathi although patholog tauopathi character abnorm tau protein aggreg gray white matter region brain neuropatholog investig general focus abnorm cerebr cortex canon aggreg form diagnost criteria disord predomin corticocentr focus tend deemphas relev complex white matter patholog remain less well character understood took data driven machin learn approach identifi novel diseas specif morpholog signatur white matter aggreg three tauopathi alzheim diseas ad progress supranuclear palsi psp corticobas degener cbd develop autom approach use whole slide imag tau immunostain section human autopsi brain ad cbd psp identifi cortexwhit matter region individu tau aggreg compar tau aggreg morpholog across diseas tau burden gray white matter individu subject strong correl high diseas specif fashion discov previous unrecogn tau morpholog ad cbd psp may import diseas classif intrigu model classifi diseas equal well base either white gray matter tau stain result suggest tau patholog white matter inform diseas specif link gray matter patholog machin learn potenti reveal latent inform histolog imag may repres previous unrecogn pattern neuropatholog addit studi tau patholog white matter could improv diagnost accuraci | D000077321 | T066 |
34,674,761 | induc pluripot stem cell improv thrombolyt effect low dose rt pa acut carotid thrombosi rat intraven thrombolysi use recombin tissu plasminogen activ rt pa standard treatment acut ischem stroke standard dose rt pa mgkg known achiev good recan carri high bleed risk lower dose rt pa less bleed risk carri high occlus rate investig induc pluripot stem cell ipsc improv thrombolyt effect low dose rt pa mgkg | D002545;D002341;D057026;D020521 | T025;T047;T046 |
34,674,760 | glaesserella parasui serotyp hps yc disrupt integr swine tracheal epitheli barrier facilit bacteri transloc glaesserella parasui g parasui commens bacterium upper respiratori tract pig also caus swine glsser diseas induc intens inflammatori respons result signific econom loss swine industri worldwid g parasui caus diseas infect respiratori tract result system infect mechan larg unknown recent show glaesserella parasui serotyp gps increas swine tracheal epitheli barrier permeabl result easier bacteri transloc tight junction protein tj play crucial role maintain integr imperm epitheli barrier gps decreas express tj zo occludin swine tracheal epitheli cell stec furthermor proinflammatori cytokin il il tnf signific upregul gps infect stec mapk nf b signal pathway activ contribut express tnf demonstr product proinflammatori cytokin especi tnf gps infect involv barrier dysfunct addit anim challeng experi confirm gps infect downregul tj lung piglet induc sever inflammatori respons general g parasui infect downregul express tj induc massiv secret proinflammatori cytokin result epitheli barrier disrupt favor bacteri infect studi allow us better understand mechan g parasui cross respiratori tract pig | D018988;D015398 | T043;T044 |
34,674,754 | increas urban reduc effect school closur season influenza epidem china school closur common mitig strategi sever influenza epidem pandem howev effect strategi remain controversi studi aim explor effect school closur season influenza epidem provinci level administr divis plad vari urban rate china | D058872;D007251;D012574;D014507 | T047;T073;T083;T068;T067;T092 |
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