Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questions
Paper • 2402.18060 • Published • 2
question stringclasses 10
values | choicesA stringclasses 10
values | choicesB stringclasses 10
values | choicesC stringclasses 10
values | choicesD stringclasses 10
values | answer_idx stringclasses 4
values | answer stringclasses 10
values | explanation stringclasses 10
values | link stringclasses 10
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|---|---|---|---|---|---|---|---|---|
A 21-year-old woman presents to her primary care physician due to a history of abdominal pain. She states that she has had recurrent bouts of mood swings, bloating, and abdominal pain that occur together approximately every 4 weeks. She states that when these symptoms occur, she gets into frequent arguments at work, is... | Premenstrual dysophoric disorder | Premenstrual syndrome | Major depressive disorder | Generalized anxiety disorder | A | Premenstrual dysophoric disorder | This patient with recurrent abdominal pain, bloating, and mood changes causing interpersonal difficulties related to the menstrual cycle likely has premenstrual dysphoric disorder. Premenstrual dysphoric disorder is a variant of premenstrual syndrome (PMS) characterized by prominent irritability and disruption of every... | https://step2.medbullets.com/testview?qid=216746 |
A 48-year-old woman, gravida 3 para 3, presents to the clinic with a 5-month history of intermittent loss of urine. Her urinary leaking occurs throughout the day and night, and she often has to get up to use the bathroom while asleep. Exercising does not affect the loss of urine. She states that she often cannot make i... | Overflow incontinence | Urge incontinence | Stress incontinence | Mixed urinary incontinence | B | Urge incontinence | This patient with a sudden need to void followed by loss of urine with urgency (unable to make it to the bathroom in time) most likely has urinary urge incontinence.
Urge incontinence is a form of urinary incontinence characterized by a sudden urge to urinate, resulting in the involuntary leakage of urine. Normally, b... | https://step2.medbullets.com/testview?qid=216248 |
A 44-year-old man presents to the emergency department acutely confused. The patient’s wife states she found him lethargic at home. He has been sick the past week with diarrhea and has been staying home from work. He is otherwise healthy and does not take any medications. His temperature is 97.5°F (36.4°C), blood press... | Loperamide | Norepinephrine | Ceftriaxone | Normal saline | A | Loperamide | This patient is presenting with infectious diarrhea (given his bloody diarrhea and hypotension) with unstable vitals that improve with fluids. In bloody diarrhea, loperamide is contraindicated and could worsen illness.
Bacterial diarrhea is commonly caused by organisms such as Campylobacter, Shigella, and Escherichia ... | https://step2.medbullets.com/testview?qid=216585 |
A 55-year-old man presents to the emergency department after fainting while moving furniture. He states that he has been working in a hot, humid attic all day and forgot his water bottle. He felt dizzy when standing up and then fainted and was unconscious for roughly 1 minute. He awoke at his neurologic baseline afterw... | Atrial fibrillation | Torsades des pointes | Stroke | Complete heart block | D | Complete heart block | This patient is presenting with dizziness and syncope in the setting of likely dehydration (working in a hot/humid environment without water) and feels better after rehydration, suggesting a diagnosis of orthostatic hypotension. An ECG is performed and incidentally demonstrates a bifascicular block, which is at high ri... | https://step2.medbullets.com/testview?qid=216637 |
A 55-year-old man with a history of polysubstance abuse is found down in his home acutely obtunded. Emergency medical services administered naloxone which immediately woke the patient up and improved his oxygen saturation from 40% to 90%. However, they noted subsequently that the patient demonstrated increased work of ... | Medication administration | Community acquired pneumonia | Atypical pneumonia | Poor cardiac function | A | Medication administration | This patient is presenting after administration of naloxone with respiratory distress, wheezing, crackles, and pulmonary edema on chest radiography, suggesting acute pulmonary edema. Given the presence of symptoms immediately following naloxone administration, the cause of the pulmonary edema is likely the naloxone (me... | https://step2.medbullets.com/testview?qid=216360 |
A 42-year-old man presents to the urgent care clinic with low back pain. He was working on a home improvement project the day prior to presentation when the pain started. He describes the pain as "achy and sore." It is not positional and does not radiate. He denies fevers, chills, paresthesias, and bowel or bladder inc... | Osteoarthritis | Vertebral compression fracture | Lumbar strain | Disc herniation | C | Lumbar strain | This patient presents with low back pain after activity with paravertebral tenderness and without red flag signs/symptoms, such as history of trauma or malignancy, intravenous drug use, saddle anesthesia (reduced perineal sensation), or neurological deficits. The most likely diagnosis is a lumbar strain.
The different... | https://step2.medbullets.com/testview?qid=216255 |
A 77-year-old man presents to the emergency department acutely obtunded. The patient lives alone and was found unresponsive by his son. Generally, the patient manages his own finances, medications, and works part-time. He has not been responding to phone calls for the past 3 days. The patient is unable to offer a histo... | Levothyroxine administration | Free T4 level | Thyroid stimulating hormone and free T4 level | Triiodothyronine administration | A | Levothyroxine administration | This elderly patient with a past medical history of hypothyroidism is presenting with altered mental status, hypotension, hypothermia, and bradycardia, which are concerning for myxedema coma. Empiric and immediate treatment with levothyroxine is the appropriate management of this condition prior to confirming the diagn... | https://step2.medbullets.com/testview?qid=216587 |
A 52-year-old G3P3 woman presents to clinic with a 2-year history of urinary incontinence. She has had frequent, involuntary loss of urine over the last 2 years but presented today because of 10 days of dysuria. She has been treated for 2 urinary tract infections over the past 6 months. She does not endorse any loss of... | Urethral diverticulum | Overflow incontinence | Stress urinary incontinence | Pelvic organ prolapse | A | Urethral diverticulum | This patient is presenting with a history of dysuria, incontinence, and recurrent lower urinary tract infections in conjunction with a tender anterior vaginal wall mass. The most likely diagnosis is a urethral diverticulum.
A urethral diverticulum is an abnormal, localized outpouching of the urethral mucosa often due ... | https://step2.medbullets.com/testview?qid=216247 |
A 48-year-old man presents to the emergency room with a 2-hour history of severe abdominal pain, nausea, and vomiting. He states that he has not passed gas or had a bowel movement in 4 days and his pain has worsened and become constant over the past 2 hours. His only medical history includes an appendectomy that he und... | Supportive care, NPO, and intravenous fluids | Urgent surgical intervention | Nasogastric tube placement | CT angiography of the abdomen and pelvis | B | Urgent surgical intervention | This patient with abdominal pain, vomiting, and obstipation is now hemodynamically unstable with fever, leukocytosis, rising lactate, and worsening pain. He most likely has a complicated small-bowel obstruction (SBO) and should undergo immediate surgical intervention.
SBO occurs when the normal progression of intralum... | https://step2.medbullets.com/testview?qid=216246 |
A 26-year-old woman presents to the emergency department because she feels as though her heart is "beating out of her chest." She states that she feels well apart from the discomfort of that sensation. Her temperature is 97.9°F (36.6°C), blood pressure is 124/84 mmHg, pulse is 180/min, respirations are 22/min, and oxyg... | Tachycardia | Photosensitivity | Flushing | Seizure | C | Flushing | This patient presents with a narrow complex tachycardia that is regular which is suggestive of supraventricular tachycardia (SVT) and was pharmacologically cardioverted with adenosine (as it has a very short half-life). Side effects of adenosine include flushing, hypotension, bronchospasm, and heart block.
SVT present... | https://step2.medbullets.com/testview?qid=106849 |
This dataset was created based on the format specified in the paper Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questions by Hanjie Chen, Zhouxiang Fang, Yash Singla, and Mark Dredze.
If you use this dataset format, please consider citing the original paper as follows:
@misc{chen2024benchmarkinglargelanguagemodels,
title={Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questions},
author={Hanjie Chen and Zhouxiang Fang and Yash Singla and Mark Dredze},
year={2024},
eprint={2402.18060},
archivePrefix={arXiv},
primaryClass={cs.CL},
url={https://arxiv.org/abs/2402.18060},
}