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stringlengths 262
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Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cccc([N+](=O)[O-])c1CO
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(O)c1[N+](=O)[O-]
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CNC(=O)Oc1ccccc1OC(C)C
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1C
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(Cl)cc1Cl
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cccc([N+](=O)[O-])c1C
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccccc1SSC(F)=C(Cl)Cl
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(Cc1ccc(F)cc1)N=O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Clc1cccc(Cl)c1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1cc(I)c(O)c([N+](=O)[O-])c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: OCCOc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)OC(=O)COc1ccc(Cl)cc1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCCOC(=O)c1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)C(=O)Nc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cc(Cl)c(N)c(Cl)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cc(Cl)ccc1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1NO
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1c(C)c(Br)c(Br)c(Br)c1Br
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=CN(O)c1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cc([N+](=O)[O-])cc(Cl)c1O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(O)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=NN(O)c1ccccc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOc1ccc(N)cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CON(C)C(=O)Nc1ccc(Br)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc([N+](=O)[O-])cc1Cl
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1cccc(O)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: C[C@@H](O)c1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=S)(OC)Oc1ccc([N+](=O)[O-])cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOS(=O)(=O)c1ccccc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCO[P@](=S)(CC)Sc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc([N+](=O)[O-])c(N)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc([N+](=O)[O-])c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccccc1C(=O)O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Brc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(N)c(S(=O)(=O)O)cc1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(O)c(N)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C/C=C/c1ccccc1[N+](=O)[O-]
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccc(I)c([N+](=O)[O-])c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cccc(O)c1N
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1c(N)ccc(N)c1C
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)c1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCCCCCCCCCOC(=O)c1ccccc1C(=O)OCCCCCCCCCCCCC
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1OCC(=O)O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(CN=[N+]=[N-])c1ccccc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(N)c(C)c([N+](=O)[O-])c1N
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(C)C(=O)Nc1ccc(Cl)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccccc1C=O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1cc(F)ccc1[N+](=O)[O-]
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCC(=O)OCc1cccc([N+](=O)[O-])c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)(C)C(Br)C(=O)Nc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1O[C@H](C)C(=O)O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc([N+](=O)[O-])ccc1[N+](=O)[O-]
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cccc(NO)c1C
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Oc1cc(Cl)c(Cl)cc1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccccc1C(F)(F)F
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)c1ccc(Cl)c(Cl)c1Cl
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1cc(N)ccc1NC(C)=O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)Oc1ccc(CO)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccccc1N
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)Cc1ccc([N+](=O)[O-])cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)c1cc(NC(N)=O)ccc1OC[C@H](O)CNC(C)(C)C
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOP(=O)(NC(C)CC)Oc1cc(C)ccc1[N+](=O)[O-]
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: NCCc1cc(O)c(O)cc1O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)COc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCNc1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1ccccc1Br
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(NO)c1ccccc1O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1c(O)cccc1[N+](=O)[O-]
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1c(N)cc(C)c(N)c1C
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1ccc(CCl)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COC(=O)c1ccccc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CN(Cc1cccc(C(F)(F)F)c1)N=O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCOc1ccc(N=O)cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(S(=O)(=O)O)c(N)cc1Cl
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCCCCc1cc(O)cc(O)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=Cc1cccc(Cl)c1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCOc1ccc(NC(N)=O)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1C(=O)O
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Nc1ccc(CO)c([N+](=O)[O-])c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=S)(OC)Oc1ccc(N)c(C)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=CN(O)c1ccc(Cl)c(Cl)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1ccc(C=O)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc(C=O)cc1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COP(=O)(OC)O/C(=C\Cl)c1cc(Cl)c(Cl)cc1Cl
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#[N+]c1ccc([N+](=O)[O-])cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=[N+]([O-])c1cccc(S(=O)(=O)O)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: COc1ccc(O)c(C(C)(C)C)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)Cc1ccc(O)c(O)c1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1ccccc1O
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CCc1cccc(CC)c1NC(=O)CO
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(CNC(=O)c1ccccc1)NO
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: N#Cc1ccccc1C#N
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(C)C(=O)N(O)c1ccc(Cl)cc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: CC(=O)NNc1ccccc1
Answer:
|
(B)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: O=C(O)CCC(=O)Nc1cc(Cl)cc(Cl)c1
Answer:
|
(A)
|
Instructions: Answer the following question about drug properties.
Context: Mutagenicity means the ability of a drug to induce genetic alterations. Drugs that can cause damage to the DNA can result in cell death or other severe adverse effects. Nowadays, the most widely used assay for testing the mutagenicity of compounds is the Ames experiment which was invented by a professor named Ames. The Ames test is a short-term bacterial reverse mutation assay detecting a large number of compounds which can induce genetic damage and frameshift mutations.
Question: Given a drug SMILES string, predict whether it
(A) is not mutagenic (B) is mutagenic
Drug SMILES: Cc1cc(Cl)ccc1/N=C/N(C)C
Answer:
|
(A)
|
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