text
stringlengths
7
1.01k
autosome genomic imprinting epigenetic programing of female pronucleus epigenetic programming in the zygotic pronuclei genomic imprinting negative regulation of gene expression via CpG island methylation negative regulation of transcription by RNA polymerase II post-fertilization epigenetic regulation of gene expressio...
ectodermal cell differentiation embryonic ectodermal digestive tract development endocytic recycling Golgi to vacuole transport lysosomal transport protein targeting protein transport retrograde transport, endosome to Golgi vesicle-mediated cholesterol transport
locomotory exploration behavior negative regulation of large conductance calcium-activated potassium channel activity negative regulation of monoatomic ion transmembrane transport negative regulation of protein-containing complex assembly positive regulation of protein-containing complex assembly positive regulation of...
glycogen catabolic process glycophagy intracellular transport substrate localization to autophagosome
acylglycerol homeostasis cholesterol efflux cholesterol homeostasis lipid transport lipoprotein metabolic process phospholipid efflux positive regulation of fatty acid biosynthetic process positive regulation of lipid catabolic process positive regulation of triglyceride catabolic process positive regulation of very-lo...
negative regulation of calcium ion-dependent exocytosis negative regulation of SNARE complex assembly proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination synaptic vesicle exocytosis
amyloid precursor protein catabolic process amyloid-beta formation locomotory behavior membrane protein ectodomain proteolysis membrane protein intracellular domain proteolysis Notch receptor processing Notch signaling pathway prepulse inhibition protein processing short-term memory synaptic transmission, dopaminergic ...
cap-independent translational initiation circadian regulation of gene expression circadian regulation of translation enteroendocrine cell differentiation entrainment of circadian clock by photoperiod glucose homeostasis insulin secretion involved in cellular response to glucose stimulus IRES-dependent translational ini...
endocrine pancreas development glucose homeostasis pancreatic A cell differentiation pancreatic D cell differentiation pancreatic epsilon cell differentiation positive regulation of DNA-templated transcription positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation...
protein O-linked glycosylation protein O-linked glycosylation via threonine
double-strand break repair via nonhomologous end joining interstrand cross-link repair nucleotide-excision repair protection from non-homologous end joining at telomere telomere capping telomere maintenance telomere maintenance via telomere lengthening telomeric 3' overhang formation telomeric loop formation
negative regulation of transcription by RNA polymerase II
endomitotic cell cycle mitotic cell cycle negative regulation of DNA-templated transcription protein neddylation regulation of cell cycle
3'-UTR-mediated mRNA destabilization positive regulation of apoptotic process response to hypoxia
anterior/posterior pattern specification embryonic limb morphogenesis embryonic skeletal system morphogenesis mesenchymal cell development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II neural tube closure positive regulation of DNA-templated transcription p...
muscle organ development neuromuscular junction development proteolysis
DNA-templated transcription negative regulation of cell migration negative regulation of Rho protein signal transduction
cellular response to mechanical stimulus proprioception
synapse organization
negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of gene expression, epigenetic retinal rod cell development
adult behavior angiogenesis cell adhesion chemical synaptic transmission learning neurotransmitter receptor localization to postsynaptic specialization membrane neurotransmitter secretion postsynaptic density assembly presynaptic modulation of chemical synaptic transmission regulation of postsynaptic membrane neurotran...
myelination zinc export across plasma membrane zinc ion import into synaptic vesicle
DNA repair
B cell activation calcineurin-NFAT signaling cascade ERK1 and ERK2 cascade negative regulation of B cell activation negative regulation of calcineurin-NFAT signaling cascade negative regulation of ERK1 and ERK2 cascade retrograde transport, endosome to Golgi
double-strand break repair via homologous recombination negative regulation of DNA-templated transcription negative regulation of gene expression, epigenetic negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of double-strand break repair via...
cyclic-GMP-AMP transmembrane import across plasma membrane negative regulation of T cell apoptotic process positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway regulation of T cell differentiation T cell homeostasis thymus development transmembrane transport
cAMP catabolic process cGMP catabolic process negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of protein kinase A signaling signal transduction
piRNA processing RNA methylation siRNA processing
cellular response to bile acid cellular response to ethanol detection of calcium ion positive regulation of potassium ion transmembrane transport response to calcium ion vasodilation
defense response to virus DNA damage checkpoint signaling double-strand break repair innate immune response negative regulation of gene expression negative regulation of transcription by RNA polymerase II positive regulation of defense response to virus by host positive regulation of DNA-templated transcription positiv...
CD4-positive, alpha-beta T cell activation CD4-positive, alpha-beta T cell differentiation defense response to virus innate immune response negative regulation of protein secretion negative regulation of viral genome replication ossification positive regulation of immune response positive regulation of T-helper 2 cell ...
positive regulation of Golgi to plasma membrane protein transport
cytoplasmic translation neurogenesis tRNA methylation tRNA nucleoside ribose methylation wobble position ribose methylation
angiogenesis axon guidance camera-type eye morphogenesis cell chemotaxis cell-substrate adhesion central nervous system projection neuron axonogenesis cranial nerve development dendritic spine development dendritic spine morphogenesis detection of temperature stimulus involved in sensory perception of pain ephrin recep...
negative regulation of toll-like receptor 3 signaling pathway protein K48-linked ubiquitination
cellular response to leukemia inhibitory factor epithelial structure maintenance establishment of localization in cell peptide hormone secretion positive regulation of peptide hormone secretion protein localization to tricellular tight junction regulation of RNA splicing response to fatty acid tricellular tight junctio...
anterior commissure morphogenesis camera-type eye development cholesterol efflux cholesterol homeostasis cholesterol metabolic process ciliary body morphogenesis corpus callosum morphogenesis energy homeostasis hippocampus development inner ear receptor cell stereocilium organization lateral ventricle development negat...
dendrite morphogenesis lamellipodium morphogenesis megakaryocyte development postsynapse to nucleus signaling pathway somitogenesis
nuclear-transcribed mRNA poly(A) tail shortening positive regulation of translation
calcium ion import chemical synaptic transmission membrane depolarization during atrial cardiac muscle cell action potential membrane depolarization during AV node cell action potential neuromuscular junction development positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel p...
cortical cytoskeleton organization modification of dendritic spine positive regulation of actin filament bundle assembly postsynaptic modulation of chemical synaptic transmission regulation of long-term neuronal synaptic plasticity regulation of postsynaptic cytosolic calcium ion concentration regulation of stress fibe...
cell cycle cell division DNA replication negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein ubiquitination regulation of cell cycle process regulation of DNA-templated transcription regulation of mitotic cell cycle, embryonic regulation of transcr...
mRNA splicing, via spliceosome ribonucleoprotein complex localization spliceosomal tri-snRNP complex assembly
apoptotic process chromatin remodeling negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of transcription by RNA polymerase II positive regulation of apoptotic process positive regulation of DNA-templated transcription regulation of DNA-templated transcription
DNA damage checkpoint signaling DNA repair erythrocyte differentiation hematopoietic stem cell differentiation negative regulation of apoptotic process negative regulation of IRE1-mediated unfolded protein response negative regulation of NF-kappaB transcription factor activity negative regulation of protein ubiquitinat...
negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein catabolic process regulation of transcription by RNA polymerase II
brain development establishment of protein localization to chromatin negative regulation of gene expression, epigenetic negative regulation of transcription by RNA polymerase II negative regulation of transcription of nucleolar large rRNA by RNA polymerase I nucleosome assembly positive regulation of keratinocyte diffe...
activation of innate immune response adaptive immune response defense response to fungus inflammatory response innate immune response positive regulation of defense response to bacterium positive regulation of inflammatory response positive regulation of interleukin-1 alpha production positive regulation of interleukin...
angiogenesis autophagy cell-cell signaling cellular response to estrogen stimulus positive regulation of catalytic activity positive regulation of endothelial cell migration positive regulation of transcription by RNA polymerase II regulation of actin cytoskeleton organization response to estrogen response to starvatio...
cellular response to lipopolysaccharide MAPK cascade mRNA processing poly(A)+ mRNA export from nucleus positive regulation of polynucleotide adenylyltransferase activity regulation of mRNA 3'-end processing
calcium import into the mitochondrion mitochondrial calcium ion homeostasis mitochondrial calcium ion transmembrane transport negative regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration
regulation of cell population proliferation ribosome biogenesis
extracellular matrix organization positive regulation of angiogenesis positive regulation of cell-substrate adhesion positive regulation of DNA biosynthetic process positive regulation of endothelial cell chemotaxis positive regulation of endothelial cell migration positive regulation of fibroblast growth factor recept...
cellular response to arsenic-containing substance extrinsic apoptotic signaling pathway in absence of ligand hemopoiesis intracellular signal transduction protein phosphorylation regulation of translation
meiotic cell cycle piRNA processing regulatory ncRNA-mediated gene silencing
germ-line stem cell population maintenance meiotic cell cycle negative regulation of circadian rhythm oogenesis piRNA processing piRNA-mediated retrotransposon silencing by heterochromatin formation positive regulation of meiosis I positive regulation of translation regulatory ncRNA-mediated gene silencing retrotranspo...
maternal behavior negative regulation of endoplasmic reticulum unfolded protein response negative regulation of glucocorticoid mediated signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of prolactin signaling pathway positive regulation of protein catabolic process positive...
meiotic nuclear division negative regulation of cell cycle process negative regulation of meiotic nuclear division negative regulation of protein catabolic process protein catabolic process protein ubiquitination regulation of meiotic nuclear division regulation of mitotic nuclear division
autophagosome assembly autophagosome maturation autophagosome membrane docking autophagy cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endosome to lysosome transport macroautophagy mitophagy negative regulation of protein phosphorylation phosphatidylin...
clathrin-dependent endocytosis endocytosis focal adhesion assembly focal adhesion disassembly platelet-derived growth factor receptor signaling pathway regulation of endocytosis ruffle assembly substrate-dependent cell migration synaptic vesicle endocytosis
protein side chain deglutamylation proteolysis
protein side chain deglutamylation proteolysis
adenosine metabolic process dephosphorylation lipid metabolic process lysosome organization nucleotide metabolic process positive regulation of adenosine receptor signaling pathway purine nucleobase metabolic process regulation of sensory perception of pain thiamine metabolic process
cell cycle positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
grooming behavior locomotory behavior neuropeptide signaling pathway positive regulation of blood pressure regulation of feeding behavior
apoptotic process cellular response to interleukin-1 cellular response to lipopolysaccharide cellular response to osmotic stress JNK cascade phosphorylation positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of JNK cascade positive regulation of JUN kinas...
fibroblast growth factor receptor signaling pathway protein homooligomerization spermatid development
cell-cell signaling monoatomic cation transport monoatomic ion transmembrane transport positive regulation of interleukin-1 production
defense response to virus innate immune response positive regulation of apoptotic process positive regulation of type I interferon-mediated signaling pathway protein deubiquitination protein K48-linked deubiquitination protein K63-linked deubiquitination protein stabilization proteolysis
fusion of sperm to egg plasma membrane involved in single fertilization maintenance of protein localization in endoplasmic reticulum sperm-egg recognition
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
aorta development cardiac septum development coronary vasculature development heart morphogenesis in utero embryonic development lung development non-canonical NF-kappaB signal transduction positive regulation of MAPK cascade transforming growth factor beta receptor signaling pathway
insulin secretion nitric oxide mediated signal transduction positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to glucose
protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine
complement activation, lectin pathway cranial skeletal system development defense response embryo development ending in birth or egg hatching heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules positive regulation of opsonization proteolysis
canonical NF-kappaB signal transduction cellular response to lipopolysaccharide interleukin-1-mediated signaling pathway intracellular signal transduction lipopolysaccharide-mediated signaling pathway regulation of cytokine-mediated signaling pathway response to interleukin-1 Toll signaling pathway toll-like receptor 4...
gamete generation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
activation of innate immune response cellular response to lipopolysaccharide cellular response to type II interferon cytolysis in another organism defense response to bacterium defense response to virus inflammatory response positive regulation of AIM2 inflammasome complex assembly positive regulation of cytokine produ...
carbohydrate metabolic process lipid glycosylation negative regulation of apoptotic process oligosaccharide biosynthetic process positive regulation of cell population proliferation protein glycosylation response to nematode response to retinoic acid
DNA damage response double-strand break repair via classical nonhomologous end joining positive regulation of DNA repair proteasome-mediated ubiquitin-dependent protein catabolic process protein autoubiquitination protein polyubiquitination regulation of transcription-coupled nucleotide-excision repair response to oxid...
chromatin organization erythrocyte differentiation negative regulation of DNA-templated transcription negative regulation of gene expression positive regulation of megakaryocyte differentiation regulation of transcription by RNA polymerase II
brain development clathrin-dependent endocytosis endosome to lysosome transport negative regulation of canonical Wnt signaling pathway positive regulation of clathrin-dependent endocytosis positive regulation of receptor internalization pyramidal neuron development receptor internalization involved in canonical Wnt sig...
alanine transport amino acid import amino acid transmembrane transport amino acid transport cellular response to amino acid starvation cellular response to arsenite(3-) cellular response to mechanical stimulus cerebral cortex development female pregnancy glutamine transport glycine betaine transport L-glutamine import ...
cell differentiation mRNA transport nuclear envelope organization protein auto-ADP-ribosylation protein transport spermatogenesis
bone development cartilage development chondrocyte development embryonic skeletal system development esophagus smooth muscle contraction glial cell-derived neurotrophic factor receptor signaling pathway glomerular basement membrane development glomerular filtration heparan sulfate proteoglycan metabolic process innerva...
male mating behavior ovarian follicle development regulation of transcription by RNA polymerase II sex differentiation
complement activation, classical pathway innate immune response proteolysis
insulin receptor signaling pathway intracellular signal transduction negative regulation of glycolytic process negative regulation of lipid biosynthetic process negative regulation of transcription from RNA polymerase II promoter by glucose protein autophosphorylation protein phosphorylation regulation of insulin recep...
cell cycle cellular response to interferon-beta negative regulation of cAMP-mediated signaling positive regulation of inclusion body assembly positive regulation of neuron apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination protein monoubiquitination pro...
autophagy cellular response to amino acid starvation cellular response to nutrient levels positive regulation of macroautophagy positive regulation of TOR signaling positive regulation of TORC1 signaling protein K6-linked ubiquitination protein localization to plasma membrane regulation of autophagy
intracellular protein transport positive regulation of ERK1 and ERK2 cascade positive regulation of MAPK cascade regulation of MAPK export from nucleus
neurotransmitter receptor localization to postsynaptic specialization membrane postsynaptic density assembly regulation of synapse maturation
autophagosome assembly macroautophagy negative regulation of protein localization osteoblast differentiation positive regulation of DNA-templated transcription protein localization tissue homeostasis ubiquitin-dependent protein catabolic process
axonogenesis nervous system development neuron projection extension presynaptic modulation of chemical synaptic transmission
apoptotic process flavin adenine dinucleotide biosynthetic process FMN biosynthetic process phosphorylation reactive oxygen species metabolic process riboflavin biosynthetic process riboflavin metabolic process
chloride transmembrane transport chloride transport establishment of localization in cell
glucose metabolic process NADP metabolic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch regulation of cortisol biosynthetic process
aerobic respiration cytochrome complex assembly heme A biosynthetic process heme O biosynthetic process lipid metabolic process mitochondrial fission mitochondrion organization respiratory chain complex IV assembly
monoatomic ion transport organic anion transport response to xenobiotic stimulus urate metabolic process urate transport
DNA synthesis involved in DNA repair DNA-templated DNA replication innate immune response regulation of DNA-templated DNA replication initiation