JuIm/Molecular_Function · Datasets at Hugging Face

text stringlengths 11 871
ATP binding glutaminase activity magnesium ion binding NAD+ synthase (glutamine-hydrolyzing) activity NAD+ synthase activity protein homodimerization activity
acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding protein-containing complex binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific enzyme binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding
G-protein alpha-subunit binding G-protein gamma-subunit binding protein kinase binding scaffold protein binding signaling receptor complex adaptor activity small GTPase binding
G-protein beta-subunit binding
ATP binding DNA binding DNA ligase (ATP) activity DNA ligase activity metal ion binding
proton transmembrane transporter activity
gap junction channel activity gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling monoatomic ion channel activity
corticotropin-releasing hormone receptor 1 binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activating protein binding GTPase activity metal ion binding mu-type opioid receptor binding signaling receptor binding
acyltransferase activity carnitine O-octanoyltransferase activity carnitine O-palmitoyltransferase activity
3' overhang single-stranded DNA endodeoxyribonuclease activity ADP-D-ribose modification-dependent protein binding enzyme binding oxidized DNA binding poly-ADP-D-ribose binding
rDNA binding
D-amino-acid dehydrogenase activity D-amino-acid oxidase activity FAD binding identical protein binding
CAAX-protein geranylgeranyltransferase activity zinc ion binding
ATP hydrolysis activity GTPase activity
ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity
carbonate dehydratase activity zinc ion binding
acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity
dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding
heme binding metal ion binding ubiquinol-cytochrome-c reductase activity
gamma-glutamyl-peptidase activity glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity
ATP binding protein serine kinase activity protein serine/threonine kinase activity
serine-type endopeptidase activity toxin activity
serine-type endopeptidase activity toxin activity
protein-containing complex binding structural constituent of muscle
scaffold protein binding structural constituent of cytoskeleton
structural constituent of skin epidermis
identical protein binding mRNA binding pre-mRNA binding RNA binding
calcium ion binding copper ion binding L-ascorbic acid binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity zinc ion binding
lipid binding lipoprotein lipase activator activity phospholipase activator activity phospholipase binding
GTP binding GTPase activity protein kinase binding
integrin binding
cytidine deaminase activity deoxycytidine deaminase activity identical protein binding zinc ion binding
chorismate mutase activity
adenylate cyclase inhibitor activity G protein-coupled receptor binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
G protein-coupled photoreceptor activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity steroid hydroxylase activity
17-alpha-hydroxyprogesterone aldolase activity heme binding iron ion binding steroid 17-alpha-monooxygenase activity
cytokine activity tumor necrosis factor receptor binding
calcium ion binding glutamate receptor binding
G protein-coupled receptor binding opsin binding
ATP binding ATP hydrolysis activity mRNA binding RNA binding RNA helicase activity
AMP binding fructose 1,6-bisphosphate 1-phosphatase activity identical protein binding metal ion binding monosaccharide binding RNA polymerase II-specific DNA-binding transcription factor binding
histidine decarboxylase activity pyridoxal phosphate binding
ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone clathrin-uncoating ATPase activity heat shock protein binding protein folding chaperone protein-macromolecule adaptor activity
DNA binding fatty acid binding metal ion binding pyridoxal phosphate binding small molecule binding toxic substance binding
actin filament binding calcium ion binding calcium-dependent protein binding protein homodimerization activity troponin I binding troponin T binding
ferric iron binding
heme binding manganese peroxidase activity metal ion binding
ATP binding beta-catenin binding identical protein binding kinase activity protein phosphatase regulator activity protein serine kinase activity protein serine/threonine kinase activity ribonucleoprotein complex binding
amino acid transmembrane transporter activity beta-alanine transmembrane transporter activity L-phenylalanine transmembrane transporter activity L-proline transmembrane transporter activity polyamine transmembrane transporter activity
GTP binding GTPase activity
chitin binding chitinase activity
beta-glucosidase activity chitinase activity lysozyme activity
RNA polymerase II-specific DNA-binding transcription factor binding
ribosome binding RNA binding translation elongation factor activity
aryl sulfotransferase activity estrone sulfotransferase activity steroid binding steroid sulfotransferase activity
antigen binding
enzyme binding glucuronosyltransferase activity protein heterodimerization activity protein homodimerization activity
erythropoietin receptor activity identical protein binding
serine-type endopeptidase activity
actin binding
metal ion binding
mRNA binding structural constituent of ribosome
signaling receptor binding
channel activity
dihydrolipoyllysine-residue succinyltransferase activity
cobalamin binding ethanolamine ammonia-lyase activity
cobalamin binding ethanolamine ammonia-lyase activity
double-stranded DNA binding protein heterodimerization activity protein homodimerization activity
cysteine-type endopeptidase inhibitor activity protease binding
3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity iron-sulfur cluster binding metal ion binding nitrate reductase activity
cell adhesion mediator activity cell adhesion molecule binding integrin binding primary amine oxidase activity
collagen binding serine-type endopeptidase inhibitor activity unfolded protein binding
G protein-coupled serotonin receptor activity G-protein alpha-subunit binding neurotransmitter receptor activity receptor-receptor interaction serotonin binding signaling receptor binding
adrenergic receptor activity alpha2-adrenergic receptor activity epinephrine binding
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding
extracellular matrix binding growth factor binding integrin binding
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity bile acid binding NAD+ binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
DNA topoisomerase binding identical protein binding insulin receptor substrate binding mRNA 5'-UTR binding PH domain binding RNA binding telomeric DNA binding
molecular adaptor activity mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA regulatory element binding translation repressor activity poly(A) binding poly(U) RNA binding poly-pyrimidine tract binding pre-mRNA binding RNA binding
calcium ion binding tropomyosin binding
amine binding carboxylic acid binding hydroxymethylbilane synthase activity uroporphyrinogen-III synthase activity
D-glucose transmembrane transporter activity glucose transmembrane transporter activity glucose uniporter activity
ATP binding metal ion binding methionine adenosyltransferase activity
bHLH transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding
ATP binding ATP hydrolysis activity mRNA binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism zinc ion binding
ATP binding fructokinase activity glucokinase activity glucosamine kinase activity glucose binding hexokinase activity mannokinase activity peptidoglycan binding
ATP binding ATP-dependent protein folding chaperone hydrolase activity protein-macromolecule adaptor activity
DNA binding metal ion binding
DNA binding DNA-directed 5'-3' RNA polymerase activity protein dimerization activity
DNA binding DNA-directed 5'-3' RNA polymerase activity
identical protein binding
hormone activity
ATP binding cholate-CoA ligase activity
bile-acid-CoA transferase activity choloyl-CoA hydrolase activity
4 iron, 4 sulfur cluster binding aconitate hydratase activity double-stranded DNA binding iron-sulfur cluster binding metal ion binding single-stranded DNA binding
chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor coactivator activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding

ATP binding glutaminase activity magnesium ion binding NAD+ synthase (glutamine-hydrolyzing) activity NAD+ synthase activity protein homodimerization activity

acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding protein-containing complex binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific enzyme binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding

G-protein alpha-subunit binding G-protein gamma-subunit binding protein kinase binding scaffold protein binding signaling receptor complex adaptor activity small GTPase binding

G-protein beta-subunit binding

ATP binding DNA binding DNA ligase (ATP) activity DNA ligase activity metal ion binding

proton transmembrane transporter activity

gap junction channel activity gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling monoatomic ion channel activity

corticotropin-releasing hormone receptor 1 binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activating protein binding GTPase activity metal ion binding mu-type opioid receptor binding signaling receptor binding

acyltransferase activity carnitine O-octanoyltransferase activity carnitine O-palmitoyltransferase activity

3' overhang single-stranded DNA endodeoxyribonuclease activity ADP-D-ribose modification-dependent protein binding enzyme binding oxidized DNA binding poly-ADP-D-ribose binding

rDNA binding

D-amino-acid dehydrogenase activity D-amino-acid oxidase activity FAD binding identical protein binding

CAAX-protein geranylgeranyltransferase activity zinc ion binding

ATP hydrolysis activity GTPase activity

ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity

carbonate dehydratase activity zinc ion binding

acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity

dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding

heme binding metal ion binding ubiquinol-cytochrome-c reductase activity

gamma-glutamyl-peptidase activity glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity

ATP binding protein serine kinase activity protein serine/threonine kinase activity

serine-type endopeptidase activity toxin activity

protein-containing complex binding structural constituent of muscle

scaffold protein binding structural constituent of cytoskeleton

structural constituent of skin epidermis

identical protein binding mRNA binding pre-mRNA binding RNA binding

calcium ion binding copper ion binding L-ascorbic acid binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity zinc ion binding

lipid binding lipoprotein lipase activator activity phospholipase activator activity phospholipase binding

GTP binding GTPase activity protein kinase binding

integrin binding

cytidine deaminase activity deoxycytidine deaminase activity identical protein binding zinc ion binding

chorismate mutase activity

adenylate cyclase inhibitor activity G protein-coupled receptor binding G protein-coupled serotonin receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding

G protein-coupled photoreceptor activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding

corticosterone 18-monooxygenase activity heme binding iron ion binding steroid 11-beta-monooxygenase activity steroid hydroxylase activity

17-alpha-hydroxyprogesterone aldolase activity heme binding iron ion binding steroid 17-alpha-monooxygenase activity

cytokine activity tumor necrosis factor receptor binding

calcium ion binding glutamate receptor binding

G protein-coupled receptor binding opsin binding

ATP binding ATP hydrolysis activity mRNA binding RNA binding RNA helicase activity

AMP binding fructose 1,6-bisphosphate 1-phosphatase activity identical protein binding metal ion binding monosaccharide binding RNA polymerase II-specific DNA-binding transcription factor binding

histidine decarboxylase activity pyridoxal phosphate binding

ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone clathrin-uncoating ATPase activity heat shock protein binding protein folding chaperone protein-macromolecule adaptor activity

DNA binding fatty acid binding metal ion binding pyridoxal phosphate binding small molecule binding toxic substance binding

actin filament binding calcium ion binding calcium-dependent protein binding protein homodimerization activity troponin I binding troponin T binding

ferric iron binding

heme binding manganese peroxidase activity metal ion binding

ATP binding beta-catenin binding identical protein binding kinase activity protein phosphatase regulator activity protein serine kinase activity protein serine/threonine kinase activity ribonucleoprotein complex binding

amino acid transmembrane transporter activity beta-alanine transmembrane transporter activity L-phenylalanine transmembrane transporter activity L-proline transmembrane transporter activity polyamine transmembrane transporter activity

GTP binding GTPase activity

chitin binding chitinase activity

beta-glucosidase activity chitinase activity lysozyme activity

RNA polymerase II-specific DNA-binding transcription factor binding

ribosome binding RNA binding translation elongation factor activity

aryl sulfotransferase activity estrone sulfotransferase activity steroid binding steroid sulfotransferase activity

antigen binding

enzyme binding glucuronosyltransferase activity protein heterodimerization activity protein homodimerization activity

erythropoietin receptor activity identical protein binding

serine-type endopeptidase activity

actin binding

metal ion binding

mRNA binding structural constituent of ribosome

signaling receptor binding

channel activity

dihydrolipoyllysine-residue succinyltransferase activity

cobalamin binding ethanolamine ammonia-lyase activity

double-stranded DNA binding protein heterodimerization activity protein homodimerization activity

cysteine-type endopeptidase inhibitor activity protease binding

3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity iron-sulfur cluster binding metal ion binding nitrate reductase activity

cell adhesion mediator activity cell adhesion molecule binding integrin binding primary amine oxidase activity

collagen binding serine-type endopeptidase inhibitor activity unfolded protein binding

G protein-coupled serotonin receptor activity G-protein alpha-subunit binding neurotransmitter receptor activity receptor-receptor interaction serotonin binding signaling receptor binding

adrenergic receptor activity alpha2-adrenergic receptor activity epinephrine binding

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding

extracellular matrix binding growth factor binding integrin binding

3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity bile acid binding NAD+ binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

DNA topoisomerase binding identical protein binding insulin receptor substrate binding mRNA 5'-UTR binding PH domain binding RNA binding telomeric DNA binding

molecular adaptor activity mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA regulatory element binding translation repressor activity poly(A) binding poly(U) RNA binding poly-pyrimidine tract binding pre-mRNA binding RNA binding

calcium ion binding tropomyosin binding

amine binding carboxylic acid binding hydroxymethylbilane synthase activity uroporphyrinogen-III synthase activity

D-glucose transmembrane transporter activity glucose transmembrane transporter activity glucose uniporter activity

ATP binding metal ion binding methionine adenosyltransferase activity

bHLH transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding

ATP binding ATP hydrolysis activity mRNA binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism zinc ion binding

ATP binding fructokinase activity glucokinase activity glucosamine kinase activity glucose binding hexokinase activity mannokinase activity peptidoglycan binding

ATP binding ATP-dependent protein folding chaperone hydrolase activity protein-macromolecule adaptor activity

DNA binding metal ion binding

DNA binding DNA-directed 5'-3' RNA polymerase activity protein dimerization activity

DNA binding DNA-directed 5'-3' RNA polymerase activity

identical protein binding

hormone activity

ATP binding cholate-CoA ligase activity

bile-acid-CoA transferase activity choloyl-CoA hydrolase activity

4 iron, 4 sulfur cluster binding aconitate hydratase activity double-stranded DNA binding iron-sulfur cluster binding metal ion binding single-stranded DNA binding

chromatin binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor coactivator activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding