JuIm/Molecular_Function · Datasets at Hugging Face

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nuclear receptor activity protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TBP-class protein binding thyroid hormone binding zinc ion binding
ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity
calcium ion binding calcium-dependent protein binding identical protein binding ion binding protein homodimerization activity RAGE receptor binding S100 protein binding signaling receptor binding tau protein binding zinc ion binding
calcium ion binding calcium-dependent cysteine-type endopeptidase activity
cardiolipin binding GDP binding GTP binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity proton transmembrane transporter activity purine ribonucleotide binding transmembrane transporter activity
lipase activity malate dehydrogenase activity triglyceride lipase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity calcium ion binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity triglyceride lipase activity
L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity malate dehydrogenase activity protein homodimerization activity protein self-association
identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding
cysteine-type endopeptidase activator activity involved in apoptotic process electron transfer activity heme binding metal ion binding
urate oxidase activity
GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton
GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton
actin binding actin filament binding cytoskeletal protein binding disordered domain specific binding identical protein binding protein heterodimerization activity protein homodimerization activity
aromatic-amino-acid:2-oxoglutarate aminotransferase activity identical protein binding L-leucine:2-oxoglutarate aminotransferase activity L-phenylalanine:2-oxoglutarate aminotransferase activity L-tyrosine:2-oxoglutarate aminotransferase activity protein homodimerization activity pyridoxal phosphate binding
acyl binding G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GDP binding GTP binding GTPase activity metal ion binding protein kinase binding
G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
ATP:ADP antiporter activity
phosphoenolpyruvate carboxylase activity
magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity
metal ion binding zinc ion binding
metal ion binding zinc ion binding
metal ion binding zinc ion binding
alpha-amylase activity calcium ion binding chloride ion binding
ATP binding hydrolase activity
acetylcholine-gated monoatomic cation-selective channel activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity heterocyclic compound binding protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine-gated monoatomic cation-selective channel activity channel activity transmembrane signaling receptor activity
acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity
acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity
G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity
DNA-binding transcription repressor activity, RNA polymerase II-specific enzyme binding GTPase binding heat shock protein binding identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein homodimerization activity protein-containing complex binding RNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription corepressor activity transcription corepressor binding
growth factor activity hormone activity prolactin receptor binding
cytokine activity hormone activity prolactin receptor binding
ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase activity
chlorophyll binding metal ion binding mRNA binding protein domain specific binding
actin binding enzyme binding integrin binding procollagen-proline 4-dioxygenase activity protein disulfide isomerase activity protein heterodimerization activity protein-containing complex binding protein-disulfide reductase activity thiol oxidase activity
DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity
identical protein binding protein folding chaperone protein homodimerization activity protein kinase binding protein kinase C binding protein kinase C inhibitor activity RNA binding RNA polymerase II-specific DNA-binding transcription factor binding ubiquitin binding unfolded protein binding
aspartic-type endopeptidase inhibitor activity disordered domain specific binding enzyme binding glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity
aromatase activity demethylase activity heme binding iron ion binding testosterone 6-beta-hydroxylase activity
aspartate-tRNA ligase activity ATP binding RNA binding
ATP binding glutamate-tRNA ligase activity tRNA binding zinc ion binding
ATP binding fructokinase activity glucokinase activity glucose binding hexokinase activity mannokinase activity
ATP binding fructokinase activity glucokinase activity glucose binding hexokinase activity mannokinase activity
ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone insulin receptor binding TPR domain binding unfolded protein binding
amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-arginine transmembrane transporter activity
folic acid binding mRNA regulatory element binding translation repressor activity protein homodimerization activity sequence-specific mRNA binding thymidylate synthase activity
ATP binding DNA binding DNA ligase (ATP) activity metal ion binding
copper ion binding cytokine activity interleukin-1 receptor binding
alpha-galactosidase activity
aminopeptidase activity identical protein binding metallopeptidase activity zinc ion binding
cell adhesion molecule binding metallocarboxypeptidase activity neurexin family protein binding zinc ion binding
flavin adenine dinucleotide binding heme binding metal ion binding protein heterodimerization activity superoxide-generating NAD(P)H oxidase activity
alcohol oxidase activity flavin adenine dinucleotide binding
RNA binding
exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding identical protein binding
exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding
disordered domain specific binding RNA binding RNA-dependent RNA polymerase activity
ATP binding ATP hydrolysis activity helicase activity RNA binding
adenylate cyclase activator activity beta-2 adrenergic receptor binding corticotropin-releasing hormone receptor 1 binding D1 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity insulin-like growth factor receptor binding ionotropic glutamate receptor binding metal ion binding mu-type opioid receptor binding
glutathione binding glutathione transferase activity
enzyme binding glutathione binding glutathione transferase activity identical protein binding nickel cation binding protein homodimerization activity protein kinase binding steroid binding
DNA binding protein heterodimerization activity structural constituent of chromatin
chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin
chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin
DNA binding protein heterodimerization activity structural constituent of chromatin
DNA binding protein heterodimerization activity structural constituent of chromatin
chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin
protein-containing complex binding retinal binding retinol binding retinol transmembrane transporter activity
collagen binding
actin binding ankyrin binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride:bicarbonate antiporter activity enzyme binding hemoglobin binding protein homodimerization activity protein-containing complex binding solute:inorganic anion antiporter activity
insulin receptor activity odorant binding pheromone binding small molecule binding
insulin receptor activity odorant binding pheromone binding small molecule binding
G protein-coupled photoreceptor activity
chromatin binding damaged DNA binding dinucleotide insertion or deletion binding DNA polymerase binding DNA polymerase processivity factor activity enzyme binding histone acetyltransferase binding identical protein binding MutLalpha complex binding nuclear estrogen receptor binding protein-containing complex binding purine-specific mismatch base pair DNA N-glycosylase activity receptor tyrosine kinase binding
serine-type endopeptidase activity toxin activity
3',5'-cyclic-GMP phosphodiesterase activity cGMP binding ion binding molecular adaptor activity zinc ion binding
clathrin heavy chain binding structural molecule activity
D-ribose pyranase activity identical protein binding intramolecular lyase activity intramolecular transferase activity monosaccharide binding
ABC-type D-ribose transporter activity ABC-type monosaccharide transporter activity ATP binding ATP hydrolysis activity D-ribose transmembrane transporter activity
magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity
ATP binding ATP hydrolysis activity DNA binding exodeoxyribonuclease V activity helicase activity single-stranded DNA helicase activity
DNA binding exodeoxyribonuclease VII activity
cytokine activity cytokine receptor binding type I interferon receptor binding
cytokine activity type I interferon receptor binding
cytokine activity type I interferon receptor binding
dihydroorotase activity protein homodimerization activity zinc ion binding
ATP binding ATP hydrolysis activity P-type sodium:potassium-exchanging transporter activity phosphatase activity potassium ion binding protein heterodimerization activity protein-folding chaperone binding sodium ion binding steroid hormone binding
ATP binding ATP hydrolysis activity ATPase binding P-type sodium:potassium-exchanging transporter activity potassium ion binding sodium ion binding
ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity
ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity
ATP binding ATP hydrolysis activity metal ion binding P-type proton-exporting transporter activity
5-hydroxy-L-tryptophan decarboxylase activity aromatic-L-amino-acid decarboxylase activity L-dopa decarboxylase activity pyridoxal phosphate binding
4-amino-4-deoxychorismate synthase activity magnesium ion binding protein heterodimerization activity tryptophan binding
fumarate hydratase activity identical protein binding
dioxygenase activity DNA-N1-methyladenine dioxygenase activity ferrous iron binding oxidative DNA demethylase activity oxidative RNA demethylase activity
3'-5'-RNA exonuclease activity cyclic-di-GMP binding identical protein binding magnesium ion binding polyribonucleotide nucleotidyltransferase activity RNA binding
calcium ion binding metal ion binding
ATPase binding cytoskeletal protein binding fructose binding fructose-1-phosphate aldolase activity fructose-bisphosphate aldolase activity identical protein binding molecular adaptor activity

nuclear receptor activity protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TBP-class protein binding thyroid hormone binding zinc ion binding

ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity

calcium ion binding calcium-dependent protein binding identical protein binding ion binding protein homodimerization activity RAGE receptor binding S100 protein binding signaling receptor binding tau protein binding zinc ion binding

calcium ion binding calcium-dependent cysteine-type endopeptidase activity

cardiolipin binding GDP binding GTP binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity proton transmembrane transporter activity purine ribonucleotide binding transmembrane transporter activity

lipase activity malate dehydrogenase activity triglyceride lipase activity

1-acyl-2-lysophosphatidylserine acylhydrolase activity calcium ion binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity triglyceride lipase activity

L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity malate dehydrogenase activity protein homodimerization activity protein self-association

identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding

cysteine-type endopeptidase activator activity involved in apoptotic process electron transfer activity heme binding metal ion binding

urate oxidase activity

GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton

actin binding actin filament binding cytoskeletal protein binding disordered domain specific binding identical protein binding protein heterodimerization activity protein homodimerization activity

aromatic-amino-acid:2-oxoglutarate aminotransferase activity identical protein binding L-leucine:2-oxoglutarate aminotransferase activity L-phenylalanine:2-oxoglutarate aminotransferase activity L-tyrosine:2-oxoglutarate aminotransferase activity protein homodimerization activity pyridoxal phosphate binding

acyl binding G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GDP binding GTP binding GTPase activity metal ion binding protein kinase binding

G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding

ATP:ADP antiporter activity

phosphoenolpyruvate carboxylase activity

magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity

metal ion binding zinc ion binding

alpha-amylase activity calcium ion binding chloride ion binding

ATP binding hydrolase activity

acetylcholine-gated monoatomic cation-selective channel activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity heterocyclic compound binding protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity channel activity transmembrane signaling receptor activity

acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity

acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity

G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity

DNA-binding transcription repressor activity, RNA polymerase II-specific enzyme binding GTPase binding heat shock protein binding identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein homodimerization activity protein-containing complex binding RNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription corepressor activity transcription corepressor binding

growth factor activity hormone activity prolactin receptor binding

cytokine activity hormone activity prolactin receptor binding

ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase activity

chlorophyll binding metal ion binding mRNA binding protein domain specific binding

actin binding enzyme binding integrin binding procollagen-proline 4-dioxygenase activity protein disulfide isomerase activity protein heterodimerization activity protein-containing complex binding protein-disulfide reductase activity thiol oxidase activity

DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity

identical protein binding protein folding chaperone protein homodimerization activity protein kinase binding protein kinase C binding protein kinase C inhibitor activity RNA binding RNA polymerase II-specific DNA-binding transcription factor binding ubiquitin binding unfolded protein binding

aspartic-type endopeptidase inhibitor activity disordered domain specific binding enzyme binding glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity

aromatase activity demethylase activity heme binding iron ion binding testosterone 6-beta-hydroxylase activity

aspartate-tRNA ligase activity ATP binding RNA binding

ATP binding glutamate-tRNA ligase activity tRNA binding zinc ion binding

ATP binding fructokinase activity glucokinase activity glucose binding hexokinase activity mannokinase activity

ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone insulin receptor binding TPR domain binding unfolded protein binding

amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-arginine transmembrane transporter activity

folic acid binding mRNA regulatory element binding translation repressor activity protein homodimerization activity sequence-specific mRNA binding thymidylate synthase activity

ATP binding DNA binding DNA ligase (ATP) activity metal ion binding

copper ion binding cytokine activity interleukin-1 receptor binding

alpha-galactosidase activity

aminopeptidase activity identical protein binding metallopeptidase activity zinc ion binding

cell adhesion molecule binding metallocarboxypeptidase activity neurexin family protein binding zinc ion binding

flavin adenine dinucleotide binding heme binding metal ion binding protein heterodimerization activity superoxide-generating NAD(P)H oxidase activity

alcohol oxidase activity flavin adenine dinucleotide binding

RNA binding

exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding identical protein binding

exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding

disordered domain specific binding RNA binding RNA-dependent RNA polymerase activity

ATP binding ATP hydrolysis activity helicase activity RNA binding

adenylate cyclase activator activity beta-2 adrenergic receptor binding corticotropin-releasing hormone receptor 1 binding D1 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity insulin-like growth factor receptor binding ionotropic glutamate receptor binding metal ion binding mu-type opioid receptor binding

glutathione binding glutathione transferase activity

enzyme binding glutathione binding glutathione transferase activity identical protein binding nickel cation binding protein homodimerization activity protein kinase binding steroid binding

DNA binding protein heterodimerization activity structural constituent of chromatin

chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin

DNA binding protein heterodimerization activity structural constituent of chromatin

chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin

protein-containing complex binding retinal binding retinol binding retinol transmembrane transporter activity

collagen binding

actin binding ankyrin binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride:bicarbonate antiporter activity enzyme binding hemoglobin binding protein homodimerization activity protein-containing complex binding solute:inorganic anion antiporter activity

insulin receptor activity odorant binding pheromone binding small molecule binding

G protein-coupled photoreceptor activity

chromatin binding damaged DNA binding dinucleotide insertion or deletion binding DNA polymerase binding DNA polymerase processivity factor activity enzyme binding histone acetyltransferase binding identical protein binding MutLalpha complex binding nuclear estrogen receptor binding protein-containing complex binding purine-specific mismatch base pair DNA N-glycosylase activity receptor tyrosine kinase binding

serine-type endopeptidase activity toxin activity

3',5'-cyclic-GMP phosphodiesterase activity cGMP binding ion binding molecular adaptor activity zinc ion binding

clathrin heavy chain binding structural molecule activity

D-ribose pyranase activity identical protein binding intramolecular lyase activity intramolecular transferase activity monosaccharide binding

ABC-type D-ribose transporter activity ABC-type monosaccharide transporter activity ATP binding ATP hydrolysis activity D-ribose transmembrane transporter activity

magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity

ATP binding ATP hydrolysis activity DNA binding exodeoxyribonuclease V activity helicase activity single-stranded DNA helicase activity

DNA binding exodeoxyribonuclease VII activity

cytokine activity cytokine receptor binding type I interferon receptor binding

cytokine activity type I interferon receptor binding

dihydroorotase activity protein homodimerization activity zinc ion binding

ATP binding ATP hydrolysis activity P-type sodium:potassium-exchanging transporter activity phosphatase activity potassium ion binding protein heterodimerization activity protein-folding chaperone binding sodium ion binding steroid hormone binding

ATP binding ATP hydrolysis activity ATPase binding P-type sodium:potassium-exchanging transporter activity potassium ion binding sodium ion binding

ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity

ATP binding ATP hydrolysis activity metal ion binding P-type proton-exporting transporter activity

5-hydroxy-L-tryptophan decarboxylase activity aromatic-L-amino-acid decarboxylase activity L-dopa decarboxylase activity pyridoxal phosphate binding

4-amino-4-deoxychorismate synthase activity magnesium ion binding protein heterodimerization activity tryptophan binding

fumarate hydratase activity identical protein binding

dioxygenase activity DNA-N1-methyladenine dioxygenase activity ferrous iron binding oxidative DNA demethylase activity oxidative RNA demethylase activity

3'-5'-RNA exonuclease activity cyclic-di-GMP binding identical protein binding magnesium ion binding polyribonucleotide nucleotidyltransferase activity RNA binding

calcium ion binding metal ion binding

ATPase binding cytoskeletal protein binding fructose binding fructose-1-phosphate aldolase activity fructose-bisphosphate aldolase activity identical protein binding molecular adaptor activity