JuIm/Molecular_Function · Datasets at Hugging Face

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antigen binding
structural molecule activity
RNA binding structural molecule activity zinc ion binding
arylsulfatase activity metal ion binding N-acetylgalactosamine-4-sulfatase activity
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding
chromatin DNA binding DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent of chromatin
ADP binding AMP binding ATP binding calcium ion binding chromatin DNA binding dATP binding DNA binding double-stranded DNA binding GTP binding histone deacetylase binding nucleosomal DNA binding nucleotide binding structural constituent of chromatin
DNA binding DNA polymerase processivity factor activity identical protein binding
2-isopropylmalate synthase activity acetyl-CoA C-acetyltransferase activity manganese ion binding
cadherin binding enzyme binding fibroblast growth factor binding mRNA binding RNA binding structural constituent of ribosome
ephrin receptor binding GTPase activator activity metal ion binding
beta-catenin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TFIIB-class transcription factor binding
actin filament binding
beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity sialyltransferase activity
metalloendopeptidase activity metallopeptidase activity toxin activity zinc ion binding
ATPase binding proton-transporting ATPase activity, rotational mechanism
bHLH transcription factor binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding mitogen-activated protein kinase kinase kinase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding
damaged DNA binding enzyme binding G-rich strand telomeric DNA binding protein phosphatase binding single-stranded DNA binding telomeric DNA binding ubiquitin protein ligase binding
heparin binding identical protein binding serine-type endopeptidase inhibitor activity transition metal ion binding
endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity
endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity
endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity
endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity
endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity
peptide antigen binding signaling receptor binding
identical protein binding mRNA binding unfolded protein binding
L-phenylalanine transmembrane transporter activity L-tryptophan transmembrane transporter activity L-tyrosine transmembrane transporter activity
ADP binding angiostatin binding ATP binding MHC class I protein binding protease binding proton-transporting ATP synthase activity, rotational mechanism
coreceptor activity interleukin-16 binding interleukin-16 receptor activity MHC class II protein binding MHC class II protein complex binding protein homodimerization activity protein tyrosine kinase binding zinc ion binding
identical protein binding lysozyme activity
carbonate dehydratase activity nickel cation binding phosphatase activity zinc ion binding
alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding
chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity
metalloendopeptidase inhibitor activity molecular function inhibitor activity peptidase inhibitor activity protease binding zinc ion binding
chromatin binding histone binding NF-kappaB binding RNA binding unfolded protein binding
growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding
carbohydrate binding galactose binding identical protein binding lactose binding laminin binding
identical protein binding serine-type endopeptidase activity
cytokine activity growth factor activity identical protein binding transforming growth factor beta binding type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding
arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity phosphatidylinositol-4,5-bisphosphate binding
G protein activity G protein-coupled receptor binding G-protein beta-subunit binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase regulator activity guanyl-nucleotide exchange factor adaptor activity metal ion binding
androgen binding DNA binding DNA-binding transcription factor activity estradiol binding estrogen response element binding nuclear estrogen receptor activity nuclear estrogen receptor binding protein homodimerization activity steroid hormone binding zinc ion binding
GTP binding guanylate cyclase activity heme binding metal ion binding
collagen binding hyaluronic acid binding transmembrane signaling receptor activity
bHLH transcription factor binding DNA-binding transcription activator activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding promoter-specific chromatin binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding
isocitrate dehydrogenase (NADP+) activity metal ion binding
damaged DNA binding DNA binding enzyme binding histone binding protein heterodimerization activity structural constituent of chromatin
calcium ion binding calcium-dependent protein binding fucose binding glycosphingolipid binding heparin binding lipopolysaccharide binding oligosaccharide binding sialic acid binding
L-lactate dehydrogenase activity
alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity
6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity fructose-6-phosphate binding identical protein binding kinase binding
identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding
ATP binding ATP hydrolysis activity magnesium chelatase activity
ATP binding proton-transporting ATPase activity, rotational mechanism
DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding
heat shock protein binding Hsp70 protein binding transmembrane signaling receptor activity
urate oxidase activity
tachykinin receptor activity
mRNA binding rRNA binding structural constituent of ribosome
peptide antigen binding signaling receptor binding
peptide antigen binding signaling receptor binding
acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding
serine-type endopeptidase inhibitor activity
aspartic-type endopeptidase activity identical protein binding peptidase activity
11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid binding
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity
DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding
malate dehydrogenase (decarboxylating) (NADP+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity
1-(5-phosphoribosyl)-5-imidazole-4-carboxamide isomerase activity phosphoribosylanthranilate isomerase activity
cholesterol binding phosphatidylinositol-4-phosphate binding sterol transfer activity
cytochrome-c oxidase activity heme binding metal ion binding
4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding
ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding
beta-galactosidase activity galactoside binding protein homodimerization activity
protein homodimerization activity transmembrane signaling receptor activity
RNA-dependent RNA polymerase activity
structural constituent of virion
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity
calcium ion binding endopeptidase activity serine-type endopeptidase activity
calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity
calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity
coreceptor activity cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding interleukin-2 receptor activity
1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity platelet-activating factor acetyltransferase activity sterol esterase activity
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylesterase activity carboxylic ester hydrolase activity fatty-acyl-ethyl-ester synthase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity
adenylate kinase activity ATP binding nucleoside diphosphate kinase activity zinc ion binding
diazepam binding GABA-A receptor activity GABA-gated chloride ion channel activity heterocyclic compound binding inhibitory extracellular ligand-gated monoatomic ion channel activity protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
cytokine binding growth factor binding growth hormone receptor activity identical protein binding lipid binding peptide hormone binding protein homodimerization activity protein kinase binding protein phosphatase binding SH2 domain binding
cysteine-type peptidase activity
2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding
cobalamin binding GTPase activity identical protein binding metal ion binding methylmalonyl-CoA mutase activity modified amino acid binding protein homodimerization activity
metal ion binding metalloendopeptidase inhibitor activity protease binding
DNA binding DNA-directed 5'-3' RNA polymerase activity metal ion binding protein dimerization activity
CRD domain binding DNA-binding transcription factor binding HMG box domain binding transcription corepressor activity transcription factor binding
DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding
DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding
G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
cytokine receptor activity interleukin-4 receptor activity
DNA binding
1,2-diacylglycerol acylhydrolase activity 1,3-diacylglycerol acylhydrolase activity acylglycerol lipase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity hormone-sensitive lipase activity retinyl-palmitate esterase activity rRNA primary transcript binding sterol esterase activity triglyceride lipase activity

antigen binding

structural molecule activity

RNA binding structural molecule activity zinc ion binding

arylsulfatase activity metal ion binding N-acetylgalactosamine-4-sulfatase activity

DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding

chromatin DNA binding DNA binding double-stranded DNA binding nucleosomal DNA binding structural constituent of chromatin

ADP binding AMP binding ATP binding calcium ion binding chromatin DNA binding dATP binding DNA binding double-stranded DNA binding GTP binding histone deacetylase binding nucleosomal DNA binding nucleotide binding structural constituent of chromatin

DNA binding DNA polymerase processivity factor activity identical protein binding

2-isopropylmalate synthase activity acetyl-CoA C-acetyltransferase activity manganese ion binding

cadherin binding enzyme binding fibroblast growth factor binding mRNA binding RNA binding structural constituent of ribosome

ephrin receptor binding GTPase activator activity metal ion binding

beta-catenin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TFIIB-class transcription factor binding

actin filament binding

beta-galactoside alpha-2,6-sialyltransferase activity protein homodimerization activity sialyltransferase activity

metalloendopeptidase activity metallopeptidase activity toxin activity zinc ion binding

ATPase binding proton-transporting ATPase activity, rotational mechanism

bHLH transcription factor binding cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific E-box binding mitogen-activated protein kinase kinase kinase binding protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding

damaged DNA binding enzyme binding G-rich strand telomeric DNA binding protein phosphatase binding single-stranded DNA binding telomeric DNA binding ubiquitin protein ligase binding

heparin binding identical protein binding serine-type endopeptidase inhibitor activity transition metal ion binding

endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides serine-type endopeptidase activity serine-type peptidase activity

endopeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides peptidase activity serine-type endopeptidase activity serine-type peptidase activity

peptide antigen binding signaling receptor binding

identical protein binding mRNA binding unfolded protein binding

L-phenylalanine transmembrane transporter activity L-tryptophan transmembrane transporter activity L-tyrosine transmembrane transporter activity

ADP binding angiostatin binding ATP binding MHC class I protein binding protease binding proton-transporting ATP synthase activity, rotational mechanism

coreceptor activity interleukin-16 binding interleukin-16 receptor activity MHC class II protein binding MHC class II protein complex binding protein homodimerization activity protein tyrosine kinase binding zinc ion binding

identical protein binding lysozyme activity

carbonate dehydratase activity nickel cation binding phosphatase activity zinc ion binding

alcohol dehydrogenase (cytochrome c(L)) activity calcium ion binding

chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity

metalloendopeptidase inhibitor activity molecular function inhibitor activity peptidase inhibitor activity protease binding zinc ion binding

chromatin binding histone binding NF-kappaB binding RNA binding unfolded protein binding

growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding

carbohydrate binding galactose binding identical protein binding lactose binding laminin binding

identical protein binding serine-type endopeptidase activity

cytokine activity growth factor activity identical protein binding transforming growth factor beta binding type I transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding

arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity phosphatidylinositol-4,5-bisphosphate binding

G protein activity G protein-coupled receptor binding G-protein beta-subunit binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase regulator activity guanyl-nucleotide exchange factor adaptor activity metal ion binding

androgen binding DNA binding DNA-binding transcription factor activity estradiol binding estrogen response element binding nuclear estrogen receptor activity nuclear estrogen receptor binding protein homodimerization activity steroid hormone binding zinc ion binding

GTP binding guanylate cyclase activity heme binding metal ion binding

collagen binding hyaluronic acid binding transmembrane signaling receptor activity

bHLH transcription factor binding DNA-binding transcription activator activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding promoter-specific chromatin binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding

isocitrate dehydrogenase (NADP+) activity metal ion binding

damaged DNA binding DNA binding enzyme binding histone binding protein heterodimerization activity structural constituent of chromatin

calcium ion binding calcium-dependent protein binding fucose binding glycosphingolipid binding heparin binding lipopolysaccharide binding oligosaccharide binding sialic acid binding

L-lactate dehydrogenase activity

alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity glycerol dehydrogenase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reductase activity retinal dehydrogenase activity

6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity fructose-6-phosphate binding identical protein binding kinase binding

identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding

ATP binding ATP hydrolysis activity magnesium chelatase activity

ATP binding proton-transporting ATPase activity, rotational mechanism

DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific DNA binding

heat shock protein binding Hsp70 protein binding transmembrane signaling receptor activity

urate oxidase activity

tachykinin receptor activity

mRNA binding rRNA binding structural constituent of ribosome

peptide antigen binding signaling receptor binding

acyl-CoA dehydrogenase activity butyryl-CoA dehydrogenase activity flavin adenine dinucleotide binding

serine-type endopeptidase inhibitor activity

aspartic-type endopeptidase activity identical protein binding peptidase activity

11-beta-hydroxysteroid dehydrogenase (NADP+) activity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity cortisol dehydrogenase activity NADP binding protein homodimerization activity steroid binding

all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity lipase activity metal ion binding triglyceride lipase activity

DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding

malate dehydrogenase (decarboxylating) (NADP+) activity metal ion binding NAD binding oxaloacetate decarboxylase activity

1-(5-phosphoribosyl)-5-imidazole-4-carboxamide isomerase activity phosphoribosylanthranilate isomerase activity

cholesterol binding phosphatidylinositol-4-phosphate binding sterol transfer activity

cytochrome-c oxidase activity heme binding metal ion binding

4 iron, 4 sulfur cluster binding aconitate hydratase activity metal ion binding

ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding

beta-galactosidase activity galactoside binding protein homodimerization activity

protein homodimerization activity transmembrane signaling receptor activity

RNA-dependent RNA polymerase activity

structural constituent of virion

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity identical protein binding phosphoglycerate mutase activity

calcium ion binding endopeptidase activity serine-type endopeptidase activity

calcium ion binding endopeptidase activity metal ion binding peptidase activity serine-type endopeptidase activity

coreceptor activity cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding interleukin-2 receptor activity

1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity platelet-activating factor acetyltransferase activity sterol esterase activity

all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity carboxylesterase activity carboxylic ester hydrolase activity fatty-acyl-ethyl-ester synthase activity retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity

adenylate kinase activity ATP binding nucleoside diphosphate kinase activity zinc ion binding

diazepam binding GABA-A receptor activity GABA-gated chloride ion channel activity heterocyclic compound binding inhibitory extracellular ligand-gated monoatomic ion channel activity protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

cytokine binding growth factor binding growth hormone receptor activity identical protein binding lipid binding peptide hormone binding protein homodimerization activity protein kinase binding protein phosphatase binding SH2 domain binding

cysteine-type peptidase activity

2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding

cobalamin binding GTPase activity identical protein binding metal ion binding methylmalonyl-CoA mutase activity modified amino acid binding protein homodimerization activity

metal ion binding metalloendopeptidase inhibitor activity protease binding

DNA binding DNA-directed 5'-3' RNA polymerase activity metal ion binding protein dimerization activity

CRD domain binding DNA-binding transcription factor binding HMG box domain binding transcription corepressor activity transcription factor binding

DNA-binding transcription repressor activity, RNA polymerase II-specific nuclear receptor activity protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding

G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding

cytokine receptor activity interleukin-4 receptor activity

DNA binding

1,2-diacylglycerol acylhydrolase activity 1,3-diacylglycerol acylhydrolase activity acylglycerol lipase activity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity hormone-sensitive lipase activity retinyl-palmitate esterase activity rRNA primary transcript binding sterol esterase activity triglyceride lipase activity