Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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compound eye morphogenesis cuticle pattern formation Golgi to plasma membrane protein transport imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis positive regulation of protein secretion positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway regul... | cell projection; early endosome; endoplasmic reticulum membrane; endosome membrane; extracellular exosome; Golgi membrane; multivesicular body; neuromuscular junction; plasma membrane; postsynaptic membrane; presynaptic membrane; synaptic vesicle membrane | Wnt-protein binding | Drosophila willistoni | Cell membrane Cell projection Developmental protein Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Membrane Postsynaptic cell membrane Reference proteome Segmentation polarity protein Synapse Transmembrane Transmembrane helix Wnt signaling pathway | MSGTILENLS | MSGTILENLSGRKLSILVSILLLCQVLCFLLGGIFAPVPAGHLTILGSLCRENHARQNDTNFFLYSRGDGACKQVTSEEVDADALKLANQIVHVFQLPLPRENKILEYTRWQQNLIGVLQVEFGYDSSPELHEPAKELQLTIDMRLAYRNNDDADNDWKLYAHSVEHRYLDCDTSHIGPTETLYTCDMIPLFELGALHHSFYLLNLRFPLDSPKQMNLQFGHMHDLTLTAIHQNGGFTKVWLFLKSVLFPFVVGIMVWFWRRVHLLQRSPALLEYMLIYLGGALTFLNLPLEYLTLGLEMPYMLLLSDIRQGIFYAMLLS... | compound eye morphogenesis cuticle pattern formation Golgi to plasma membrane protein transport imaginal disc-derived leg morphogenesis imaginal disc-derived wing margin morphogenesis positive regulation of protein secretion positive regulation of Wnt protein secretion positive regulation of Wnt signaling pathway regul... |
adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... | centrosome; chromosome; lipid droplet; membrane; microtubule; neuromuscular junction; spindle; synaptic vesicle; terminal bouton | ATP binding ATP hydrolysis activity isomerase activity microtubule binding microtubule severing ATPase activity | Drosophila willistoni | ATP-binding Cell cycle Cell division Chromosome Cytoplasm Cytoskeleton Developmental protein Differentiation Isomerase Lipid droplet Membrane Microtubule Mitosis Neurogenesis Nucleotide-binding Reference proteome | MVRTKSSSSS | MVRTKSSSSSASSSSQKSPIKSNNGAGGGGSSSSHRQSHRTSIDERKSSSHAHSNNSNVSSSSRRAATATSGSSSPEGDDDTTTDDLTPTGSSPRSCNGRGHSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVLYRPHRRDCNIEIVVQNSKEQQLQLQQHQHNQTLSYSLETGGVSGGSGGEQQVQVQPQRIRALQPLEMATNRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWNGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREEDL... | adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... |
anatomical structure morphogenesis cell-cell signaling involved in cell fate commitment intein-mediated protein splicing protein autoprocessing segment polarity determination self proteolysis system development | cytoplasm; nucleus; plasma membrane | cholesterol-protein transferase activity metal ion binding morphogen activity peptidase activity | Drosophila willistoni | Autocatalytic cleavage Calcium Cell membrane Cytoplasm Developmental protein Hydrolase Lipoprotein Membrane Metal-binding Morphogen Nucleus Palmitate Protease Reference proteome Segmentation polarity protein Signal Transferase | MDSQSNQTPW | MDSQSNQTPWASASVTCLSLDAKRHSQCLDDAIKSGHQVNYSPARSLRYIAYTQRCGIRLTMLMLIMCLTFMPAHSCGPGRGLGRRRVQNLYPLVLKQTVPNLSEHQLGASGPLEGEIPRDSPKFKDLVPNYNRDIVFKDEEGTGADRLMTKRCREKLNALAYSVMNEWPGVRLLVIESWDEDHDHGQESLHYEGRAVTIGTNDRDLSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSTISHVHGCFTPESTAQMENGEKKPLSQLSIGDRVLSMGSNGQPVYSEVILFMDRNLEQLENFVQLHTDGGAVLTVTPA... | anatomical structure morphogenesis cell-cell signaling involved in cell fate commitment intein-mediated protein splicing protein autoprocessing segment polarity determination self proteolysis system development cytoplasm; nucleus; plasma membrane cholesterol-protein transferase activity metal ion binding morphogen acti... |
compound eye development cuticle pattern formation homotypic cell-cell adhesion maintenance of protein location in extracellular region segment specification smoothened signaling pathway wing disc anterior/posterior pattern formation | cell surface; cytoneme; membrane; plasma membrane | coreceptor activity hedgehog family protein binding heparin binding patched binding protein homodimerization activity | Drosophila yakuba | Disulfide bond Glycoprotein Heparin-binding Immunoglobulin domain Membrane Proteoglycan Repeat Signal Transmembrane Transmembrane helix | MTLLTSSLLF | MTLLTSSLLFFSLLTSRLEAIPVLEKSPAHPAHSAHPAHPSHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSSGAGFKYLRTGTAKANVSQEAAISRLKVLVRQDTLGEYRCVGWFGPLVVTSTIARLELASTSLLGGQESESPLQWRVSAGNSVLWPCGKQVKSNPSASWSYYRNGVEIKPEFIGTNGNIFLSNVSSESSGSYSCQATNPASGERIQLTGSLQLQVTPEQRSQSKSPHLLNGQPNSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVIGHALEISNTRVQDAG... | compound eye development cuticle pattern formation homotypic cell-cell adhesion maintenance of protein location in extracellular region segment specification smoothened signaling pathway wing disc anterior/posterior pattern formation cell surface; cytoneme; membrane; plasma membrane coreceptor activity hedgehog family ... |
detection of light stimulus involved in visual perception histamine transport protein adenylylation protein deadenylylation response to endoplasmic reticulum stress visual behavior | plasma membrane | AMPylase activity ATP binding Hsp70 protein binding protein adenylylhydrolase activity protein homodimerization activity | Drosophila yakuba | ATP-binding Hydrolase Membrane Nucleotide-binding Nucleotidyltransferase Repeat TPR repeat Transferase Transmembrane Transmembrane helix | MGTEAEQPSP | MGTEAEQPSPPSPPAQQQEQTNPPLWNAQNQKPARLYRLVLFFIAGSLAAWTIHALSNSNLVWKLRQLHHLPTAHYLQTRDEFAVYSVEELNAFKEIYDKSVSDSVGASYTKDEQTSINEALVSLRMAQDMYLAGKDDKASRLFEHALALAPRHPEVLLRYGEFLEHSQRNIVLADQYYFQALTISPSNSEALANRQRTADVVQTLDERRLQSLDSKRDALSAIHESNGALRRAKKEAYFQHIYHSVGIEGNTMTLAQTRSILETRMAVDGKSIDEHNEILGMDLAMKYINASLVQKIDITIKDILELHRRVLGHVDPIE... | detection of light stimulus involved in visual perception histamine transport protein adenylylation protein deadenylylation response to endoplasmic reticulum stress visual behavior plasma membrane AMPylase activity ATP binding Hsp70 protein binding protein adenylylhydrolase activity protein homodimerization activity Dr... |
adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... | centrosome; chromosome; lipid droplet; membrane; microtubule; neuromuscular junction; spindle; synaptic vesicle; terminal bouton | ATP binding ATP hydrolysis activity isomerase activity microtubule binding microtubule severing ATPase activity | Drosophila yakuba | ATP-binding Cell cycle Cell division Chromosome Cytoplasm Cytoskeleton Developmental protein Differentiation Isomerase Lipid droplet Membrane Microtubule Mitosis Neurogenesis Nucleotide-binding | MVRTKNQSSS | MVRTKNQSSSSSASSSSTKSPIKSSSATGSSGGGVGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHTYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNRDSDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRL... | adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... |
detection of light stimulus involved in visual perception histamine transport protein adenylylation protein deadenylylation response to endoplasmic reticulum stress visual behavior | plasma membrane | AMPylase activity ATP binding Hsp70 protein binding protein adenylylhydrolase activity protein homodimerization activity | Drosophila simulans | ATP-binding Hydrolase Membrane Nucleotide-binding Nucleotidyltransferase Reference proteome Repeat TPR repeat Transferase Transmembrane Transmembrane helix | MCMEAEPPSP | MCMEAEPPSPPAQQQEQVNPPLCKAQNPKPARLYRLVLLFVAGSLAAWTFHALSSTNLVWKLRQLHHLPTAHYLQTRDEFALYSVEELNAFKEFYDKSVSDSVGASYTEAEQTNIKEALGALRMAQDLYLAGKDDKAARLFEHALALAPRHPEVLLRYGEFLEHNQRNIVLADQYYFQALTISPSNSEALANRQRTADVVQSLDERRLESLDSKRDALSAIHESNGALRRAKKEAYFQHIYHSVGIEGNTMTLAQTRSILETRMAVDGKSIDEHNEILGMDLAMKYINASLVQKIDITIKDILELHRRVLGHVDPIEGGE... | detection of light stimulus involved in visual perception histamine transport protein adenylylation protein deadenylylation response to endoplasmic reticulum stress visual behavior plasma membrane AMPylase activity ATP binding Hsp70 protein binding protein adenylylhydrolase activity protein homodimerization activity Dr... |
compound eye development cuticle pattern formation homotypic cell-cell adhesion maintenance of protein location in extracellular region segment specification smoothened signaling pathway wing disc anterior/posterior pattern formation | cell surface; cytoneme; membrane; plasma membrane | coreceptor activity hedgehog family protein binding heparin binding patched binding protein homodimerization activity | Drosophila simulans | Disulfide bond Glycoprotein Heparin-binding Immunoglobulin domain Membrane Proteoglycan Reference proteome Repeat Signal Transmembrane Transmembrane helix | MTLLTSSLLL | MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHTAHPAHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLRTGTAKANVSQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTTARLELASTSLVDAQEPESPLQWRVSAGNSVLWSCGQQVQSNPSASWSYFRNGVEIKPEFIGTNGNLFLSNVSSESSGSYSCQATNPASGERIQLPGSLQLQVTPEQRSQSKSPHLLKGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVHDAG... | compound eye development cuticle pattern formation homotypic cell-cell adhesion maintenance of protein location in extracellular region segment specification smoothened signaling pathway wing disc anterior/posterior pattern formation cell surface; cytoneme; membrane; plasma membrane coreceptor activity hedgehog family ... |
adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... | centrosome; chromosome; lipid droplet; membrane; microtubule; neuromuscular junction; spindle; synaptic vesicle; terminal bouton | ATP binding ATP hydrolysis activity isomerase activity microtubule binding microtubule severing ATPase activity | Drosophila simulans | ATP-binding Cell cycle Cell division Chromosome Cytoplasm Cytoskeleton Developmental protein Differentiation Isomerase Lipid droplet Membrane Microtubule Mitosis Neurogenesis Nucleotide-binding Reference proteome | MVRTKNQSSS | MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGVGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRL... | adult locomotory behavior cell division hemocyte migration microtubule severing mitotic chromosome movement towards spindle pole mitotic spindle elongation negative regulation of microtubule depolymerization negative regulation of neuromuscular synaptic transmission negative regulation of synaptic assembly at neuromusc... |
anatomical structure morphogenesis cell-cell signaling involved in cell fate commitment intein-mediated protein splicing protein autoprocessing segment polarity determination self proteolysis system development | cytoplasm; nucleus; plasma membrane | cholesterol-protein transferase activity metal ion binding morphogen activity peptidase activity | Drosophila simulans | Autocatalytic cleavage Calcium Cell membrane Cytoplasm Developmental protein Hydrolase Lipoprotein Membrane Metal-binding Morphogen Nucleus Palmitate Protease Reference proteome Segmentation polarity protein Signal Transferase | MDNHSSVPWA | MDNHSSVPWASAASVTCLSLDAKCHSSSSSCSSKSTASSISASPETQTMRHIAHTQRCLSRLTSLVALLLIVLPMMFSPAHSCGPGRGLGRHRARNLYPLVLKQTIPNLSEYTNSASGPLEGVIRRDSPKFKDLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDEDYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSISSHVHGCFTPESTALLESGVRKPLGELSIGDRVLSMTANGQGVYSEVILFMDRNLEQMQNFVQLHTDGGAV... | anatomical structure morphogenesis cell-cell signaling involved in cell fate commitment intein-mediated protein splicing protein autoprocessing segment polarity determination self proteolysis system development cytoplasm; nucleus; plasma membrane cholesterol-protein transferase activity metal ion binding morphogen acti... |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane | host cell plasma membrane; membrane; virion membrane | monoatomic ion channel activity proton transmembrane transporter activity | Influenza A virus | Alternative splicing Disulfide bond Glycoprotein Host cell membrane Host membrane Host-virus interaction Hydrogen ion transport Inhibition of host autophagy by virus Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Signal-anchor Transmembrane Transmembrane helix Transport Viral ion channel Virion | MSLLTEVETP | MSLLTEVETPIRNEWGCRCNGSSDPLTIAANIIGILHLTLWILDRLFFKCIYRRFKYGLKGGPSTEGVPKSMREEYRKEQQSAVDADDGHFVSIELE | protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane host cell plasma membrane; membrane; virion membrane monoatomic ion channel activity proton transmembrane transporter activity Influenza A virus Alternative splicing Disulfide bond Glycoprotein Hos... |
cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly glial cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules neural crest cell development neuronal stem cell population maintenance synaptic vesicle clustering type B pancreatic cell development | adherens junction; cell junction; cell surface; cell-cell junction; desmosome; intercalated disc; plasma membrane; presynapse; sarcolemma | calcium ion binding | Otolemur garnettii | Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MCRIAGAPRT | MCRIAGAPRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLSVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHSKFLIYAQDKETQEKWQVAVKLSLKPTLTEESVKESPEIEEIVFPRQLTKHNGYLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNM... | cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly glial cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules neural crest cell development neuronal stem cell population maintenance synaptic vesicle clustering type B pancreatic cell development adheren... |
inner ear development phosphatidylinositol phosphate biosynthetic process phosphorylation | Golgi membrane; mitochondrial outer membrane; rough endoplasmic reticulum membrane | 1-phosphatidylinositol 4-kinase activity 14-3-3 protein binding ATP binding | Otolemur garnettii | Acetylation ATP-binding Endoplasmic reticulum Golgi apparatus Kinase Lipid metabolism Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase | MGDTVVEPTP | MGDTVVEPTPLKPTSESTPGPAGSNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVKLLHGGVAISSRNSPLELVNGDGVDNEIRCLDDPPSRIREEEDEMGATVAVGTAKGARRQRQNNSAKQSWLLRLFESKLFDISMAMSYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPV... | inner ear development phosphatidylinositol phosphate biosynthetic process phosphorylation Golgi membrane; mitochondrial outer membrane; rough endoplasmic reticulum membrane 1-phosphatidylinositol 4-kinase activity 14-3-3 protein binding ATP binding Otolemur garnettii Acetylation ATP-binding Endoplasmic reticulum Golgi... |
mannan catabolic process | extracellular region | mannan endo-1,4-beta-mannosidase activity oligosaccharide binding polysaccharide binding | Cryptopygus antarcticus | 3D-structure Carbohydrate metabolism Disulfide bond Glycosidase Hydrolase Polysaccharide degradation Secreted Signal | MVKLFSFLLL | MVKLFSFLLLVWVASPAFSSEFLKASGSNFYYGGQKVFLSGVNFAWRSYGSDFGNGQYASNGPALKDWINKVKASGGNTARVWVHVEGQVSPAFDSHGFVTSTDSKKTLINDLSDLLDYANGQNVFLILVLFNGALQNNSNVQNLFWDESKLNSYINNALTPMVNALKSKPSLAAWEVLNEPEGTLQPGSDQNSCYDTSTLAAQGAGWGGKKFPMKQILKTINWISSAIHNADSKALVTVGSWSELTQTDSFGYRNHYKDSCLTGAGGKSNGIINFYQMHTYSHSGKWNQNAPFKVNRWAYNVNDKPLLIGEFASVCSQN... | mannan catabolic process extracellular region mannan endo-1,4-beta-mannosidase activity oligosaccharide binding polysaccharide binding Cryptopygus antarcticus 3D-structure Carbohydrate metabolism Disulfide bond Glycosidase Hydrolase Polysaccharide degradation Secreted Signal MVKLFSFLLL MVKLFSFLLLVWVASPAFSSEFLKASGSNFYYG... |
fatty acid biosynthetic process fatty acid metabolic process | endoplasmic reticulum; membrane | monooxygenase activity oleate 12-hydroxylase activity omega-3 fatty acid desaturase activity oxidoreductase activity palmitoleic acid delta 12 desaturase activity phosphatidylcholine 12-monooxygenase activity | Claviceps purpurea | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Microsome Monooxygenase Oxidoreductase Transmembrane Transmembrane helix | MASATPAMSE | MASATPAMSENAVLRHKAASTTGIDYESSAAVSPAESPRTSASSTSLSSLSSLDANEKKDEYAGLLDTYGNAFTPPDFSIKDIRAAIPKHCYERSTIKSYAYVLRDLLCLSTTFYLFHNFVTPENIPSNPLRFVLWSIYTVLQGLFATGLWVIGHECGHCAFSPSPFISDLTGWVIHSALLVPYFSWKFSHSAHHKGIGNMERDMVFLPRTREQQATRLGRAVEELGDLCEETPIYTALHLVGKQLIGWPSYLMTNATGHNFHERQREGRGKGKKNGFGGGVNHFDPRSPIFEARQAKYIVLSDIGLGLAIAALVYLGNR... | fatty acid biosynthetic process fatty acid metabolic process endoplasmic reticulum; membrane monooxygenase activity oleate 12-hydroxylase activity omega-3 fatty acid desaturase activity oxidoreductase activity palmitoleic acid delta 12 desaturase activity phosphatidylcholine 12-monooxygenase activity Claviceps purpurea... |
negative regulation of membrane potential positive regulation of circadian sleep/wake cycle, sleep regulation of circadian sleep/wake cycle, sleep regulation of synaptic transmission, cholinergic rhythmic process sleep | external side of plasma membrane; plasma membrane | acetylcholine receptor inhibitor activity GPI anchor binding potassium channel activator activity | Drosophila melanogaster | Biological rhythms Cell membrane Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal | MWTQRNAVGN | MWTQRNAVGNWLLVLTAVIGFLTFIWIPQTSAECQTRSIYCYECDSWTDARCKDPFNYTALPRDQPPLMTCNGCCVKMVRHQRSPYEVVRRMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKNLHTNGCQLHLIPIAVAVSWLMGQLLSR | negative regulation of membrane potential positive regulation of circadian sleep/wake cycle, sleep regulation of circadian sleep/wake cycle, sleep regulation of synaptic transmission, cholinergic rhythmic process sleep external side of plasma membrane; plasma membrane acetylcholine receptor inhibitor activity GPI ancho... |
apoptotic process defense response to bacterium killing of cells of another organism | extracellular region | L-phenylalaine oxidase activity toxin activity | Bothrops pauloensis | Antibiotic Antimicrobial Apoptosis Cytolysis Direct protein sequencing Disulfide bond FAD Flavoprotein Glycoprotein Hemolysis Hemostasis impairing toxin Oxidoreductase Platelet aggregation activating toxin Secreted Signal Toxin | MNVFFMFSLL | MNVFFMFSLLFLAALGSCADDGNPLEECFRETDYEEFLEIAKNGLSATSNPKHVVIVGAGMSGLSAAYVLANAGHQVTVLEASKRAGGRVRTYRNDKEGWYANLGPMRLPEKHRIVREYIRKFGLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVRLNVRVIKIQQDVKEVTVTYQTSAKETLSVTADYVIVCTTSRAARRI... | apoptotic process defense response to bacterium killing of cells of another organism extracellular region L-phenylalaine oxidase activity toxin activity Bothrops pauloensis Antibiotic Antimicrobial Apoptosis Cytolysis Direct protein sequencing Disulfide bond FAD Flavoprotein Glycoprotein Hemolysis Hemostasis impairing... |
amino acid import across plasma membrane establishment of localization in cell L-alpha-amino acid transmembrane transport L-amino acid transport L-arginine import across plasma membrane L-arginine transmembrane transport L-ornithine transmembrane transport macrophage activation nitric oxide biosynthetic process nitric ... | cell junction; membrane; plasma membrane | amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine transmembrane transporter activity L-ornithine transmembrane transporter activity | Rattus norvegicus | Alternative splicing Amino-acid transport Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MIPCRAVLTF | MIPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLD... | amino acid import across plasma membrane establishment of localization in cell L-alpha-amino acid transmembrane transport L-amino acid transport L-arginine import across plasma membrane L-arginine transmembrane transport L-ornithine transmembrane transport macrophage activation nitric oxide biosynthetic process nitric ... |
chordate embryonic development egg activation embryonic morphogenesis epidermis development establishment of RNA localization miRNA transport mRNA processing mRNA stabilization negative regulation of cellular senescence negative regulation of mRNA processing negative regulation of mRNA splicing, via spliceosome negativ... | extracellular exosome; nucleus; P-body | C5-methylcytidine-containing RNA reader activity eukaryotic initiation factor 4E binding methyl-CpG binding miRNA binding nucleic acid binding RNA binding | Danio rerio | 3D-structure Alternative splicing Cytoplasm DNA-binding mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding Secreted Transcription Transcription regulation | MSSEAETQQP | MSSEAETQQPPQPAADAESPSSPAAAATAGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNRYRRYPRRRAPPRDYQENYQSDPEAEPREKREGAESAPEGEMQQQQRRPTYPGRRRYPPYFVRRRYGRRPPYTNSQRGEMTEGGEGEENQGGPDQGNKPMRQNYYRGFRPSRGPSRPRPVRDGEEDKENQSESGQNQEPRQRRYRRNFNYRRRRPQTTKPQDGKDSKAADASADKSAAPEAEQGGAD | chordate embryonic development egg activation embryonic morphogenesis epidermis development establishment of RNA localization miRNA transport mRNA processing mRNA stabilization negative regulation of cellular senescence negative regulation of mRNA processing negative regulation of mRNA splicing, via spliceosome negativ... |
cell migration cytoskeleton organization miRNA-mediated gene silencing by inhibition of translation miRNA-mediated post-transcriptional gene silencing negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription negative regulation of hippo signaling negative regulation of o... | adherens junction; cytoplasm; focal adhesion; nucleoplasm; nucleus; P-body; plasma membrane; RISC complex; transcription regulator complex | metal ion binding transcription corepressor activity | Rattus norvegicus | Cell junction Cytoplasm LIM domain Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor RNA-mediated gene silencing Transcription Transcription regulation Tumor suppressor Zinc | MDKYDDLGLE | MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGASNNPEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPINGGNRQGVSSKLAADGAAKPPLAVPTVAPGLATTTMAVQSSYPPQEQRTRPSAHGARPGSQNCGSREGPVSSQRPALHGLGPCEDPSCLTHGDYYDNFSLASPQWGDKPEESPSMSLSVGSGWPGCPGNDSLSHRSCGDSHPYHPQLSMCSGRSFESGQDSGIGGHSSEKPTGLWSTASSQRVNLGFSSTGLENGTPAQPKGTTVSAPMVPSSTSQGACLRRDSSLGYEAPGRVFKPLVDT... | cell migration cytoskeleton organization miRNA-mediated gene silencing by inhibition of translation miRNA-mediated post-transcriptional gene silencing negative regulation of canonical Wnt signaling pathway negative regulation of DNA-templated transcription negative regulation of hippo signaling negative regulation of o... |
antiviral innate immune response cellular response to misfolded protein DNA repair negative regulation of TORC1 signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein K11-linked ubiquitination protein monoubiquitination protein quality control for misfolded or incompletely synthesized prote... | nucleus | ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase binding ubiquitin-protein transferase activity | Rattus norvegicus | ATP-binding DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Transferase Ubl conjugation Ubl conjugation pathway | MASMQKRLQK | MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGENIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWWYHDDTC | antiviral innate immune response cellular response to misfolded protein DNA repair negative regulation of TORC1 signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein K11-linked ubiquitination protein monoubiquitination protein quality control for misfolded or incompletely synthesized prote... |
collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... | basement membrane; chromatin; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular space; membrane; nucleus | calcium ion binding copper ion binding oligosaccharide binding protein-lysine 6-oxidase activity | Rattus norvegicus | Basement membrane Calcium Chromatin regulator Chromosome Copper Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Repressor Secreted Signal TPQ Transcription Transcription regulation | MEIPFGSCLY | MEIPFGSCLYSCLALLVLLPSLSLAQYESWPYQLQYPEYFQQPPPEHHQHQVPSDVVKIQVRLAGQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDNIYCTGKESTLAACSSNGWGVTDCKHPEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKEGKAWKQICDKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASRRKLRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRK... | collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... |
cobalt ion transport copper ion transport iron ion transport magnesium ion transport monoatomic cation transport protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane transmembrane transport | cytoplasm; early endosome; early endosome membrane; EMC complex; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; membrane; plasma membrane | cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity inorganic cation transmembrane transporter activity magnesium ion transmembrane transporter activity membrane insertase activity | Rattus norvegicus | Endoplasmic reticulum Endosome Golgi apparatus Magnesium Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MAPSLWKGLV | MAPSLWKGLVGVGLFALAHAAFSAAQHRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDATNSSNLDALSSNTSLKLRKFDSLRR | cobalt ion transport copper ion transport iron ion transport magnesium ion transport monoatomic cation transport protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane transmembrane transport cytoplasm; early endosome; early endosome membra... |
3'-UTR-mediated mRNA stabilization mRNA destabilization mRNA stabilization negative regulation of miRNA-mediated gene silencing positive regulation of superoxide anion generation positive regulation of translation post-transcriptional gene silencing protein homooligomerization protein import into nucleus regulation of ... | cytoplasm; cytoplasmic stress granule; cytoplasmic vesicle; cytosol; endoplasmic reticulum; glutamatergic synapse; nucleoplasm; nucleus; P-body; postsynapse; ribonucleoprotein complex; sarcoplasm | double-stranded RNA binding lncRNA binding miRNA binding mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR binding mRNA binding protein homodimerization activity protein kinase binding RNA binding | Rattus norvegicus | Acetylation Cytoplasm Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Ubl conjugation | MSNGYEDHMA | MSNGYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFK... | 3'-UTR-mediated mRNA stabilization mRNA destabilization mRNA stabilization negative regulation of miRNA-mediated gene silencing positive regulation of superoxide anion generation positive regulation of translation post-transcriptional gene silencing protein homooligomerization protein import into nucleus regulation of ... |
angiogenesis cell motility cell-cell adhesion positive regulation of cell migration involved in sprouting angiogenesis positive regulation of synapse assembly regulation of phosphorylation vocalization behavior | cell surface; cytoplasm; excitatory synapse; extracellular space; synaptic membrane | hepatocyte growth factor binding identical protein binding signaling receptor binding | Rattus norvegicus | Angiogenesis Cell adhesion Cytoplasm Disulfide bond Glycoprotein Proteoglycan Reference proteome Repeat Secreted Signal Sushi Synapse | MKTGSLTQRG | MKTGSLTQRGALLLLLLLAPAVTPTWYAGSGYSPDESYNEVYAEEVPDTRALDYRVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRKSVQCLPSRRWSGTAYCRQMRCHTLPFITSGTYTCTNGMLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKIAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPILKPPQHGYLTCSSAGDNYGAICEYHCDGGYERQGTPSRVCQSSRQWSGSPPVC... | angiogenesis cell motility cell-cell adhesion positive regulation of cell migration involved in sprouting angiogenesis positive regulation of synapse assembly regulation of phosphorylation vocalization behavior cell surface; cytoplasm; excitatory synapse; extracellular space; synaptic membrane hepatocyte growth factor ... |
anaphase-promoting complex-dependent catabolic process cell division exit from mitosis free ubiquitin chain polymerization positive regulation of ubiquitin protein ligase activity protein K11-linked ubiquitination protein K27-linked ubiquitination protein K29-linked ubiquitination protein K6-linked ubiquitination prote... | anaphase-promoting complex; nucleus | anaphase-promoting complex binding ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Rattus norvegicus | Acetylation ATP-binding Cell cycle Cell division Nucleotide-binding Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway | MNSNVENLPP | MNSNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGPNGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTEIHGGACSTSSGRAEASRDLASGASASSTDPMTPGVLGGAEGPMAKKHAGERDKKLAAKKKLDKKRALRRL | anaphase-promoting complex-dependent catabolic process cell division exit from mitosis free ubiquitin chain polymerization positive regulation of ubiquitin protein ligase activity protein K11-linked ubiquitination protein K27-linked ubiquitination protein K29-linked ubiquitination protein K6-linked ubiquitination prote... |
angiotensin-activated signaling pathway apoptotic process epithelial fluid transport mitochondrion-endoplasmic reticulum membrane tethering mRNA polyadenylation one-carbon metabolic process positive regulation of sodium ion transport protein export from nucleus regulation of monoatomic anion transport regulation of mRN... | apical plasma membrane; cytoplasm; cytosol; endoplasmic reticulum; intracellular membrane-bounded organelle; mitochondria-associated endoplasmic reticulum membrane | enzyme regulator activity identical protein binding RNA binding | Rattus norvegicus | Cell membrane Cytoplasm Endoplasmic reticulum Membrane Microsome NAD One-carbon metabolism Phosphoprotein Reference proteome RNA-binding | MQEFTKFPTK | MQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQV... | angiotensin-activated signaling pathway apoptotic process epithelial fluid transport mitochondrion-endoplasmic reticulum membrane tethering mRNA polyadenylation one-carbon metabolic process positive regulation of sodium ion transport protein export from nucleus regulation of monoatomic anion transport regulation of mRN... |
cilium assembly Golgi to plasma membrane transport intraciliary transport kidney development mitotic cytokinesis photoreceptor cell development protein localization to ciliary membrane protein transport small GTPase mediated signal transduction smoothened signaling pathway | axoneme; centrosome; ciliary basal body; cilium; cytoplasmic microtubule; Golgi apparatus; Golgi membrane; midbody; nucleoplasm; nucleus; photoreceptor connecting cilium; spindle microtubule | GDP binding GTP binding GTPase activity magnesium ion binding microtubule binding | Taeniopygia guttata | Cell cycle Cell division Cell projection Cytoplasm Cytoskeleton Golgi apparatus GTP-binding Lipoprotein Membrane Myristate Nucleotide-binding Nucleus Protein transport Reference proteome Transport | MGLLSILRKL | MGLLSILRKLKSTPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRNYFENTDILIYVIDSADRKRFEETGQELAELLDEEKLSGVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALSGEGVQDGMNWVCKNVSTKKK | cilium assembly Golgi to plasma membrane transport intraciliary transport kidney development mitotic cytokinesis photoreceptor cell development protein localization to ciliary membrane protein transport small GTPase mediated signal transduction smoothened signaling pathway axoneme; centrosome; ciliary basal body; ciliu... |
embryonic cranial skeleton morphogenesis mRNA splicing, via spliceosome mRNA transport negative regulation of translation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of nuclear-transcribed mRNA... | catalytic step 2 spliceosome; cytoplasm; exon-exon junction complex; nuclear speck; nucleus; U2-type catalytic step 1 spliceosome | ATP binding ATP hydrolysis activity mRNA binding poly(A) binding RNA helicase activity | Taeniopygia guttata | ATP-binding Cytoplasm Helicase Hydrolase mRNA processing mRNA splicing mRNA transport Nonsense-mediated mRNA decay Nucleotide-binding Nucleus Reference proteome RNA-binding Spliceosome Translation regulation Transport | MAGSAGSAGG | MAGSAGSAGGSARKRLMKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK... | embryonic cranial skeleton morphogenesis mRNA splicing, via spliceosome mRNA transport negative regulation of translation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of nuclear-transcribed mRNA... |
lignin biosynthetic process | cytoplasm | cinnamyl-alcohol dehydrogenase activity zinc ion binding | Capsicum annuum | Cytoplasm Lignin biosynthesis Metal-binding NADP Oxidoreductase Reference proteome Zinc | MGSLEVEKTA | MGSLEVEKTAIGWAARDPSGILSPYTYTLRNTGPEDVQVKVLYCGLCHSDLHQVKNDLGMSNYPMVPGHEVVGEVVEVGPEVTKFKVGDTVGVGLIVGCCKNCRPCKQDIEQYCAKKIWNCNDVYTDGKPTQGGFSNFMVVEQKFVVKIPEGMAPEQAAPLLCAGVTVYSPLNHFGFNQSGLRGGILGLGGVGHMGVKIAKAMGHHVTVISSSDKKRQEALDHLGADDYLVSSVNEKMQEAADSLDYIIDTIPVNHPLEPYLSLLKVDGKLILMGVINTPLQFVSPMVMLGRKSITGSFIGSMKETEEVLHFCKEKGVTC... | lignin biosynthetic process cytoplasm cinnamyl-alcohol dehydrogenase activity zinc ion binding Capsicum annuum Cytoplasm Lignin biosynthesis Metal-binding NADP Oxidoreductase Reference proteome Zinc MGSLEVEKTA MGSLEVEKTAIGWAARDPSGILSPYTYTLRNTGPEDVQVKVLYCGLCHSDLHQVKNDLGMSNYPMVPGHEVVGEVVEVGPEVTKFKVGDTVGVGLIVGCCKNCRPCKQDI... |
arbuscular mycorrhizal association cellular response to phosphate starvation detection of phosphate ion lateral root formation phosphate ion transport response to symbiotic fungus | periarbuscular membrane; plasma membrane | inorganic phosphate transmembrane transporter activity symporter activity | Lotus japonicus | Cell membrane Glycoprotein Membrane Phosphate transport Symport Transmembrane Transmembrane helix Transport | MALEVLEALD | MALEVLEALDSARTQWYHVTAIVIAGMGFFTDAYDLFCITTVSKLLGRLYYFDPSTGKPGKLPNNVNNLVTGVALVGTLSGQLFFGYLGDKLGRKKVYGVTLILMVACAICSGLSFGASAKSVMGTLCFFRFWLGFGIGGDYPLSATIMSEYANKRTRGAFIAAVFAMQGVGIIFAGLVSMCLSAGFKASYHAPSFHDDPIMSTQPQGDLMWRLVLMIGAVPAAMTYYWRMKMPETGRYTAIIEGNAKQAAADMARVLDIEIQAEQDKLAEFKAANDYPLWSNEFFTRHGRHLIGTMTSWFLLDIAFYSQNLTQKDIFPA... | arbuscular mycorrhizal association cellular response to phosphate starvation detection of phosphate ion lateral root formation phosphate ion transport response to symbiotic fungus periarbuscular membrane; plasma membrane inorganic phosphate transmembrane transporter activity symporter activity Lotus japonicus Cell memb... |
calcium-mediated signaling using intracellular calcium source cellular response to amyloid-beta cellular response to copper ion positive regulation of neuron apoptotic process positive regulation of peptidyl-tyrosine phosphorylation protein destabilization protein homooligomerization | cell surface; cytosol; dendrite; Golgi apparatus; inclusion body; membrane raft; nuclear membrane; plasma membrane; side of membrane | amyloid-beta binding cuprous ion binding identical protein binding microtubule binding molecular condensate scaffold activity protein-containing complex binding type 5 metabotropic glutamate receptor binding | Bos indicus x Bos taurus | Amyloid Cell membrane Copper Disease variant Disulfide bond Glycoprotein Golgi apparatus GPI-anchor Lipoprotein Membrane Metal-binding Prion Reference proteome Repeat Signal Zinc | MVKSHIGSWI | MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGSDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSSPPVILLISFLIFLIVG | calcium-mediated signaling using intracellular calcium source cellular response to amyloid-beta cellular response to copper ion positive regulation of neuron apoptotic process positive regulation of peptidyl-tyrosine phosphorylation protein destabilization protein homooligomerization cell surface; cytosol; dendrite; Go... |
cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide inflammatory response innate immune response toll-like receptor signaling pathway | Golgi apparatus; membrane raft; phagocytic vesicle membrane | NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating transmembrane signaling receptor activity | Bos indicus | Cytoplasmic vesicle Disulfide bond Glycoprotein Immunity Inflammatory response Innate immunity Isopeptide bond Leucine-rich repeat Membrane NAD Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MPRALWTAWV | MPRALWTAWVWAVIILSTEGASDQASSLSCDPTGVCDGHSRSLNSIPSGLTAGVKSLDLSNNEITYVSNRDLQRCVNLKTLRLGANEIHTVEEDSFFHLRNLEYLDLSYNRLSNLSSSWFRSLYVLKFLNLLGNLYKTLGETSLFSHLPNLRTLKVGNSNSFTEIHEKDFTGLTFLEELEISAQNLQIYVPKSLKSIQNISHLILHLKQPVLLVDILVDIVSSLDCLELRDTNLHTFHFSEASISEMSTSVKKLIFRNVQFTDESFVEVVKLFNYVSGILEVEFDDCTHDGIGDFRALSLDRIRHLGNVETLTIRKLHIP... | cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide inflammatory response innate immune response toll-like receptor signaling pathway Golgi apparatus; membrane raft; phagocytic vesicle membrane NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating... |
gibberellic acid mediated signaling pathway gibberellin mediated signaling pathway phosphorylation positive regulation of cell division response to gibberellin | cytoplasm | ATP binding hydrolase activity protein serine/threonine kinase activity | Arabidopsis thaliana | Alternative splicing ATP-binding Cytoplasm Gibberellin signaling pathway Hydrolase Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAVDKVIVKQ | MAVDKVIVKQRNIILVGIPIDESGVEVLKWALEEVAKHGDCVVVVHVCFTYYRALKSKSSLDRYLKPYIEFCSTKKIELKGEVLKGNSVLGVLVKEAKRYNAMSVVVGVKQQSKLSLKIAKGCAKELPSTTDILAIHRGNIVFRRSNHYQLPLAQKISSRPSSELSEGFSDKDLAKTTGQEKRKISGRSLSLPSVEVVDQTPGWPLLRTSTLATPMVQHQTRKISVVNWVMSLPERFPHHPNQTCQQSFCDKQLKDILKDINRWFSYDVLKTATSDFSLENLIGKGGCNEVYKGFLEDGKGVAVKILKPSVKEAVKEFVH... | gibberellic acid mediated signaling pathway gibberellin mediated signaling pathway phosphorylation positive regulation of cell division response to gibberellin cytoplasm ATP binding hydrolase activity protein serine/threonine kinase activity Arabidopsis thaliana Alternative splicing ATP-binding Cytoplasm Gibberellin si... |
ribonucleotide biosynthetic process | chloroplast; mitochondrion | 5'-3' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity DNA primase activity metal ion binding single-stranded DNA binding | Arabidopsis thaliana | ATP-binding Chloroplast DNA replication DNA-binding Helicase Hydrolase Magnesium Metal-binding Mitochondrion Nucleotide-binding Nucleotidyltransferase Plastid Primosome Reference proteome Transferase Transit peptide | MRFLLRLPQI | MRFLLRLPQIHFRKLSCSMSVLMGSKQFLEFCLLPSFASYPSSPSYSSSRQVSSVSRRFRPVLASRPVSKNSPYYQRTNGLSSYNSIPRVPTPVDTEVEADKRVVLSRLVTLRRKLAEQGVDAENCPPGQHSGLICPTCEGGNSGEKSLSLFIAPDGSSATWNCFRGKCGLKGGVRADGGLASADPIEKVERKITVEGIELEPLCDEIQDYFAARAISRKTLERNRVMQKRIGDEIVIAFTYWQRGELVSCKYRSLTKMFFQERKTRRILYGLDDIEKTSEVIIVEGEIDKLAMEEAGFLNCVSVPDGAPAKVSSKEIPS... | ribonucleotide biosynthetic process chloroplast; mitochondrion 5'-3' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity DNA primase activity metal ion binding single-stranded DNA binding Arabidopsis thaliana ATP-binding Chloroplast DNA replication DNA-binding Helicase Hydrolase Magnesium Me... |
cell division DNA repair-dependent chromatin remodeling double-strand break repair mitotic G2 DNA damage checkpoint signaling positive regulation of DNA repair positive regulation of NLRP3 inflammasome complex assembly protein K63-linked deubiquitination proteolysis response to ionizing radiation | BRCA1-A complex; BRISC complex; cytoplasm; nucleus; spindle pole | cysteine-type deubiquitinase activity metal ion binding metal-dependent deubiquitinase activity metallopeptidase activity polyubiquitin modification-dependent protein binding | Salmo salar | Cell cycle Cell division Chromatin regulator Cytoplasm Cytoskeleton DNA damage DNA repair Hydrolase Metal-binding Metalloprotease Mitosis Nucleus Protease Reference proteome Ubl conjugation pathway Zinc | MAVSAVHLES | MAVSAVHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPEQLSSAATEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSVQAQKGSEYERIEIPIHVVPHEAIGKVCLESAVELPRILCQEEQDTYRKIHSLTHLDPITKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNRQSVIELQLEKERLTQELATM | cell division DNA repair-dependent chromatin remodeling double-strand break repair mitotic G2 DNA damage checkpoint signaling positive regulation of DNA repair positive regulation of NLRP3 inflammasome complex assembly protein K63-linked deubiquitination proteolysis response to ionizing radiation BRCA1-A complex; BRISC... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O157:H7 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O157:H7 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATI... |
chitin catabolic process polysaccharide catabolic process | extracellular region | chitin binding chitinase activity | Yersinia entomophaga | 3D-structure Carbohydrate metabolism Chitin degradation Glycosidase Hydrolase Polysaccharide degradation Secreted Virulence | MEKEEKSNLI | MEKEEKSNLIYDKDPGYVWDNKNECEGAAEETYQELNYEPSISADKLTWTPTRLAKTVFNTYEDDDDFNVLCYFTDWSQYDPRIINKEIRDTGGRSADILRLNTPDGRPFKRLIYSFGGLIGDKKYSADGNASIAVRLGVATDPDDAIANHKGKTIPVDPDGAVLASINCGFTKWEAGDANERYNQEKAKGLLGGFRLLHEADKELEFSLSIGGWSMSGLFSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEYPGSIGAGNPNSPDDGANFAILIQQITDAKISNLKGISIASSADPAKIDAANIPALMDAGVTGI... | chitin catabolic process polysaccharide catabolic process extracellular region chitin binding chitinase activity Yersinia entomophaga3D-structure Carbohydrate metabolism Chitin degradation Glycosidase Hydrolase Polysaccharide degradation Secreted Virulence MEKEEKSNLI MEKEEKSNLIYDKDPGYVWDNKNECEGAAEETYQELNYEPSISADKLTWTPT... |
chitin catabolic process polysaccharide catabolic process | extracellular region | chitin binding chitinase activity | Yersinia entomophaga | 3D-structure Carbohydrate metabolism Chitin degradation Glycosidase Hydrolase Polysaccharide degradation Secreted Virulence | MVNKYTYTSS | MVNKYTYTSSKAMSDISDVIGEPLAAWDSQVGGRVFNVIFDGKVYTNTYWVERWQVPGIGSSDGNPHNAWKFVRAATADEINKIGNPTTADVKPTENIPSPILVEDKYTEETYSRPDVNFKEDGSQGNLSYTATRVCAPMYNHYVGDKTKPKLSAYITDWCQYDARLDGGGSKEEERGRGFDLATLMQNPATYDRLIFSFLGICGDIGNKSKKVQEVWDGWNAQAPSLGLPQIGKGHIVPLDPYGDLGTARNVGLPPESADTSIESGTFLPYYQQNRAAGLLGGLRELQKKAHAMGHKLDLAFSIGGWSLSSYFSALAEN... | chitin catabolic process polysaccharide catabolic process extracellular region chitin binding chitinase activity Yersinia entomophaga3D-structure Carbohydrate metabolism Chitin degradation Glycosidase Hydrolase Polysaccharide degradation Secreted Virulence MVNKYTYTSS MVNKYTYTSSKAMSDISDVIGEPLAAWDSQVGGRVFNVIFDGKVYTNTYWVE... |
adaptive immune response innate immune response negative regulation of CD4-positive, alpha-beta T cell activation | plasma membrane; specific granule membrane; tertiary granule membrane | immunoglobulin receptor binding | Homo sapiens | Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Innate immunity Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MIPKLLSLLC | MIPKLLSLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQHSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSPGESEAFKPE | adaptive immune response innate immune response negative regulation of CD4-positive, alpha-beta T cell activation plasma membrane; specific granule membrane; tertiary granule membrane immunoglobulin receptor binding Homo sapiens Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity I... |
adaptive immune response innate immune response negative regulation of CD4-positive, alpha-beta T cell activation negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cytokine production involved in inflammatory response | plasma membrane | immunoglobulin receptor binding | Mus musculus | Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Innate immunity Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MISRLLSLLC | MISRLLSLLCLRLCVGQTDIPENGSPPKPSLSAWPSTVLPTKSHVTMQCKSPTPSKYFILKKEGFALNSVKPYNLTEETADFHFTDLRQNDGGHYTCEYYSKWPHDTPSHPSNALFLLVTGYLPQPSFQAHHRGTVTAGSKVTLQCQKAGSVLGPVKFALLKVGHSTPVQTRSSTGMVSDFSLQNVTARDSGEYSCVYYQAKAPYRASGPSNLLEISVIDNHLPQDLAASTFPPQLTATSPKTPGTMTEGYTVDNLIRVGVAAAILLIVGGFLVEAWHSERLSPNKPW | adaptive immune response innate immune response negative regulation of CD4-positive, alpha-beta T cell activation negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cytokine production involved in inflammatory response plasma membrane immunoglobulin receptor binding Mus musculus... |
cell cycle heterochromatin formation negative regulation of gene expression via CpG island methylation negative regulation of transcription by RNA polymerase II protein ubiquitination ubiquitin-dependent protein catabolic process | chromatin; euchromatin; heterochromatin; nucleus; replication fork | hemi-methylated DNA-binding histone binding methylated histone binding ubiquitin-protein transferase activity zinc ion binding | Xenopus laevis | Cell cycle Chromatin regulator DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Transferase Ubl conjugation pathway Zinc Zinc-finger | MWIQVRTMDG | MWIQVRTMDGRDTRRIDSLSKLTKVDDLRDRIQQLFGVALESQRLFYRGKQMENGHTLFDYSVGLNDIVQLLVRQIPDSFPTKHKECELSDASAGCGSGQRDSDSGSGEGAMDVDGQSISIIGENVGTSLYKKNDLVDARDLNMGAWFEAQIVNVSKKVGPYGTLPEVSDTSVTSDAIIYHVKYEDYPENGVVQLTCKDVRLRARTTLPWHEIKVGQVVMVNYNPDEPKERGYWYDAEILRKHESKKIKEIYAKVLLGDAGDSLNDCRIRFVNEIYKIEEPGSTYLNTESPQKRQNGPECKHCKDNPKRACRMCACCICG... | cell cycle heterochromatin formation negative regulation of gene expression via CpG island methylation negative regulation of transcription by RNA polymerase II protein ubiquitination ubiquitin-dependent protein catabolic process chromatin; euchromatin; heterochromatin; nucleus; replication fork hemi-methylated DNA-bin... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Macrovipera lebetina | Calcium Disulfide bond Hemostasis impairing toxin Hydrolase Lipid degradation Lipid metabolism Metal-binding Platelet aggregation inhibiting toxin Secreted Signal Toxin | MRTLWIVAVW | MRTLWIVAVWLTGVEGDLSQFGDMINKKTGTFGLFSYIYYGCYCGWGGKGKPQDATDRCCFVHDCCYGSVNGCDPKLSTYSYSFQNGDIVCGDDDPCLRAVCECDRVAAICSGENMNTYDKKYMLYSLFDCKEESEKC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Macrovipera lebetina Calcium Disulfide bond Hemostasis impairing toxin Hydrolase Lipid degradation Lipid metabolism Metal-binding Platelet aggregation inhi... |
cell redox homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein folding protein folding in endoplasmic reticulum release of sequestered calcium ion into cytosol response to endoplasmic reticulum stress | dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; extracellular space; Golgi lumen | FAD binding oxidoreductase activity protein-disulfide reductase activity thiol oxidase activity | Sus scrofa | Apoptosis Cell projection Disulfide bond Electron transport Endoplasmic reticulum FAD Flavoprotein Glycoprotein Golgi apparatus Membrane Oxidoreductase Phosphoprotein Redox-active center Reference proteome Secreted Signal Transport | MGHRWGFLIV | MGHRWGFLIVFLGAVGLLGSGYGRQQPSETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDINQCGRRDCAVKPCQSDEIPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPDAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGKSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVVP... | cell redox homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein folding protein folding in endoplasmic reticulum release of sequestered calcium ion into cytosol response to endoplasmic reticulum stress dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; extr... |
mRNA cis splicing, via spliceosome RNA splicing | mediator complex | RNA polymerase binding | Arabidopsis thaliana | Alternative splicing mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat | MANNPPQSSG | MANNPPQSSGTQFRPMVPGQQGQHFVPAASQPFHPYGHVPPNVQSQPPQYSQPIQQQQLFPVRPGQPVHITSSSQAVSVPYIQTNKILTSGSTQPQPNAPPMTGFATSGPPFSSPYTFVPSSYPQQQPTSLVQPNSQMHVAGVPPAANTWPVPVNQSTSLVSPVQQTGQQTPVAVSTDPGNLTPQSASDWQEHTSADGRKYYYNKRTKQSNWEKPLELMTPLERADASTVWKEFTTPEGKKYYYNKVTKESKWTIPEDLKLAREQAQLASEKTSLSEAGSTPLSHHAASSSDLAVSTVTSVVPSTSSALTGHSSSPIQAG... | mRNA cis splicing, via spliceosome RNA splicing mediator complex RNA polymerase binding Arabidopsis thaliana Alternative splicing mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat MANNPPQSSG MANNPPQSSGTQFRPMVPGQQGQHFVPAASQPFHPYGHVPPNVQSQPPQYSQPIQQQQLFPVRPGQPVHITSSSQAVSVPYIQTNKILTSGSTQPQPNAP... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDIAGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFE... |
abscisic acid-activated signaling pathway cuticle development ethylene-activated signaling pathway positive regulation of DNA-templated transcription positive regulation of response to water deprivation positive regulation of wax biosynthetic process response to abscisic acid response to osmotic stress response to wate... | nucleus | DNA-binding transcription factor activity sequence-specific DNA binding | Zea mays | Abscisic acid signaling pathway Activator DNA-binding Ethylene signaling pathway Nucleus Reference proteome Stress response Transcription Transcription regulation | MTENLHSRKM | MTENLHSRKMVQPKKFRGVRQRHWGSWVSEIRHPLLKRRVWLGTFETAEEAARAYDEAAVLMSGRNAKTNFPIQRSSTGEPTPAAGRDARSNFSSGSSTTNLSQILSAKLRKCCKAPSPSLTCLRLDPEKSHIGVWQKRAGARADSNWVMTVELNKDAASTDAASQSTSATTAPPATPMDEEERIALQMIEELLSSSSPASPSNGDDQGRFII | abscisic acid-activated signaling pathway cuticle development ethylene-activated signaling pathway positive regulation of DNA-templated transcription positive regulation of response to water deprivation positive regulation of wax biosynthetic process response to abscisic acid response to osmotic stress response to wate... |
apoptotic process cellular response to ionizing radiation DNA damage response DNA repair double-strand break repair via homologous recombination embryo development ending in birth or egg hatching meiotic chromosome separation mitotic sister chromatid segregation nucleotide-excision repair positive regulation of double-... | BRCA1-BARD1 complex; chromosome; cytoplasm | metal ion binding ubiquitin protein ligase activity | Caenorhabditis elegans | Alternative splicing Cell cycle Chromosome Cytoplasm DNA damage DNA repair Metal-binding Nucleus Reference proteome Repeat Transferase Zinc Zinc-finger | MADVALRITE | MADVALRITETVARLQKELKCGICCSTYKDPILSTCFHIFCRSCINACFERKRKVQCPICRSVLDKRSCRDTYQITMAVQNYLKLSEAFKKDIENMNTFKSLPPEKMFMESQMPLDITIIPENDGKRCAPDFAIPFLPVRRKRPSRPQPPSAFAEEPAEPVEPPEPATKQPVELQSRVFPLEKLKKDVETSTETYKISREELKNVDIEEYINTLRENSTEIDEIDALFQLMPTMRQFLRNNINQLMEKFHVAPPKKSEKPANRRVSFASSQDLENIKIMTASESLETPPEPIQKLAQKPEVFKSTQNLIDLNLNTAVKKP... | apoptotic process cellular response to ionizing radiation DNA damage response DNA repair double-strand break repair via homologous recombination embryo development ending in birth or egg hatching meiotic chromosome separation mitotic sister chromatid segregation nucleotide-excision repair positive regulation of double-... |
axon development neuroendocrine cell differentiation neuron fate commitment positive regulation of hormone secretion positive regulation of peptide secretion positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription sensory organ development ventral cord development | cytoplasm; nucleus | DNA-binding transcription factor activity E-box binding protein dimerization activity | Drosophila melanogaster | Cytoplasm Developmental protein Differentiation DNA-binding Glycoprotein Reference proteome Transcription Transcription regulation | MDATQLTELM | MDATQLTELMGSHDFMQLQHQLHHNNNNYNTDGHNGLSSESAEGSSRPVRRATRRTSQLSNNTYDLEMTDSSSQSDDTSGGGGSSNGGGSTTNTGHPSGCSLGGQGPSGRGRVQQASSGACPSTIAPNSTSSNSSNANGNASRRRKGALNAKERNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHIILSKRNEEAAALELNSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFEDTLASGGAFDCAILAATDGSLLNAATVTTSPAMQSIQSQAIHLQTPMEQQQQQASHLP... | axon development neuroendocrine cell differentiation neuron fate commitment positive regulation of hormone secretion positive regulation of peptide secretion positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription sensory organ development ventral cord development cytoplasm; ... |
negative regulation of exocytosis neuron remodeling signal transduction synapse organization | axon terminus; cytoplasm; neuronal cell body; plasma membrane | NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating | Danio rerio | Cell membrane Cytoplasm Disulfide bond Glycoprotein Hydrolase Immunoglobulin domain Membrane NAD Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MRSRVPLQIL | MRSRVPLQILLYAAVIRSLKVVSKRGSVDGCTDWSVDYLRYRVLLGEPVRIKCALFYGYIRANYTHAQSAGLSLMWYRSATHTDHEEPITLDGTRTLKEEDALWFRPAQLQDSGHYSCVLRNSSYCMKVSMALTVAENSSGLCYNSKMRRLEKAELSKSKDILCPDIQDYTPAGSEPHVTWYKECRPKQWRSSIIRTADLLSIRDVREDDIGNYTCEIQFGRFLVRRTTELTVTAPLTDKPPKILQPPEHKLSVMELQLGGPVNLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDETRIRESEIKMVREHLGEQEVSVSLT... | negative regulation of exocytosis neuron remodeling signal transduction synapse organization axon terminus; cytoplasm; neuronal cell body; plasma membrane NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating Danio rerio Cell membrane Cytoplasm Disulfide bond Glycoprotein Hydrolase Immunoglobul... |
defense response modulation of process of another organism | extracellular region | sodium channel inhibitor activity toxin activity | Centruroides suffusus | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodium channel impairing toxin | MNSLLMITAC | MNSLLMITACFFLIGTVWAKEGYLVNKSTGCKYGCLLLGKNEGCDKECKAKNQGGSYGYCYAFGCWCEGLPESTPTYPLPNKSCSKK | defense response modulation of process of another organism extracellular region sodium channel inhibitor activity toxin activity Centruroides suffusus Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodium channel imp... |
sterol biosynthetic process | endoplasmic reticulum membrane | iron ion binding monooxygenase activity | Phaeodactylum tricornutum | Endoplasmic reticulum Iron Lipid biosynthesis Lipid metabolism Membrane Oxidoreductase Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix | MLVDRVENNE | MLVDRVENNEKQQQQMASSSDAMSDSSLSDDEIIEHVVHGKEPKSTYELSWVSNAIAWSGALVWPLMLTVPLLLSSMYSPISYRQVFPESWYVYDTLSNCAPKPLGLVLGILAVAVGQVFVWIFFYLFKFGYLGTDPRSIQSKGAREYIFREGLLTHIGQPEGFVLLIGYLAITWMLKLMPQSYYSFEGTIQYKELFMCLVLQDGIQYTMHVLEHIVSPAFYQMSHKPHHRFTNPRLFDAFNGSLMDTFCMIIIPLFVTANLVRHCNVWTYMAFGSSYACWLTLIHSEYVFPWDGIFRKLGLGTPADHHVHHKFFKFNYG... | sterol biosynthetic process endoplasmic reticulum membrane iron ion binding monooxygenase activity Phaeodactylum tricornutum Endoplasmic reticulum Iron Lipid biosynthesis Lipid metabolism Membrane Oxidoreductase Reference proteome Steroid biosynthesis Transmembrane Transmembrane helix MLVDRVENNE MLVDRVENNEKQQQQMASSSDAM... |
isocitrate metabolic process NAD metabolic process tricarboxylic acid cycle | mitochondrion | calcium ion binding identical protein binding isocitrate dehydrogenase (NAD+) activity isocitrate dehydrogenase (NADP+) activity magnesium ion binding protein homodimerization activity | Phaeodactylum tricornutum | 3D-structure Calcium Magnesium Manganese Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide Tricarboxylic acid cycle | MSSLSTLRIL | MSSLSTLRILHSTAGRRWASYYGIYPKSAACSSSSVAIARFFSTAADRPPKHAMLSVENKVVAPPMVYIAGEEMTRYACDLVVKSWLEPYFDLSQWEYFDLSCVNRDNTNDQVLRDAVTAGQRIGAIFKEPTITPSAIQKKAFGLKNSLGSPNGAMRAGWNGITISRDTIHIDGIELGYKRPVFFERHAVGGEYGAGWSKVGRGTLLTTYLPSDGRDPFVVDKRDLTDQHNVVVTYHNPYDNVEPLAHLFFQRCLDANITPYVVTKKTVFKWQEGFWAVMKDVFDEHYKSRFEEKGLLQACGGDLQHLISDAATMQLIRW... | isocitrate metabolic process NAD metabolic process tricarboxylic acid cycle mitochondrion calcium ion binding identical protein binding isocitrate dehydrogenase (NAD+) activity isocitrate dehydrogenase (NADP+) activity magnesium ion binding protein homodimerization activity Phaeodactylum tricornutum 3D-structure Calciu... |
cell wall organization peptidoglycan biosynthetic process regulation of cell shape | plasma membrane | lipid-linked peptidoglycan transporter activity | Thermosipho africanus | 3D-structure Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Membrane Peptidoglycan synthesis Transmembrane Transmembrane helix Transport | MSILFSSILF | MSILFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRKVFGEGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPELIINLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFWPALTPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHKYYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYASRFYLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMVGLIFLSTPIIRFFYEHG... | cell wall organization peptidoglycan biosynthetic process regulation of cell shape plasma membrane lipid-linked peptidoglycan transporter activity Thermosipho africanus 3D-structure Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Membrane Peptidoglycan synthesis Transmembrane Transmembrane... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGTLIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLH... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O8 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQKSKNPQ | MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDIAGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O8 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQKSKNPQ MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O45:K1 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc | MTVQKSKNPQ | MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESEDVAAALQWAIENDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O45:K1 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc MTVQKSKNPQ MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETL... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O81 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O81 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLM... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O17:K52:H18 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O17:K52:H18 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFE... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O7:K1 | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc | MTVQTSKNPQ | MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHSDNPLNGYSICAFPDAADKQTPDIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAS | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O7:K1 Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Stress response Zinc MTVQTSKNPQ MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISG... |
peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase | extracellular region | glutaminyl-peptide cyclotransferase activity zinc ion binding | Ixodes scapularis | 3D-structure Acyltransferase Disulfide bond Glycoprotein Metal-binding Reference proteome Secreted Signal Transferase Zinc | MLFPVLLLLK | MLFPVLLLLKLVIGALIIDASALSWHDLKWPRDLRPLAHHDLLYMGQISEEDRGDFNATLRNFLVPRVVGSQKHREVREFIVRSLKDLDWDVEEDCFDGQTPHGIKPFCNVIATLNPSACHRLVLACHYDSLLHKEGTFIGATDSAVPCAQLLYLARSLNGKLQNQKTRGDGLTLQLVFFDGEEAFERWSSHDSLYGSRHLAQKWHEDRTSAERLESCLERSEIANQIDRMEVMVLLDLLGAENPRFYSYFGETQPVYRRLVNIESRLNDAGLMELPRRRRRTNYFSNSSTVGFIEDDHIPFLKRSVPIVHIIPSPFPDV... | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase extracellular region glutaminyl-peptide cyclotransferase activity zinc ion binding Ixodes scapularis 3D-structure Acyltransferase Disulfide bond Glycoprotein Metal-binding Reference proteome Secreted Signal Transferase Zinc MLFP... |
apoptotic process calcium-mediated signaling negative regulation of neuron apoptotic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of transcription by RNA polymerase II | nucleus | chromatin binding chromatin DNA binding phosphoprotein binding protein homodimerization activity transcription coactivator activity | Rattus norvegicus | Activator Apoptosis DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MDVRFYPAAA | MDVRFYPAAAGDPAGLDFAQCLGYYGYSKLGNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEIPPITPPPESDPTLGMPDVLLPFQTLSDPLPSQGNEFTPQFPPQSLDLPSITISRNLVEQDGVLHSNGLHMDQSHTQVSQYRQDPSLVMRSIVHMTDAARSGIMPPAQLTTINQSQLSAQLGLNLGGASVPHTSPSPPASKSATPSPSSSINEEDADETNRAVGEKRTAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAA... | apoptotic process calcium-mediated signaling negative regulation of neuron apoptotic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of transcription by RNA polymerase II nucleus chromatin binding chromatin D... |
central nervous system formation innate immune response motor neuron axon guidance negative regulation of neuron apoptotic process regulation of neuronal synaptic plasticity in response to neurotrophin Toll signaling pathway | extracellular region; extracellular space | growth factor activity receptor ligand activity Toll binding | Drosophila melanogaster | Alternative splicing Disulfide bond Glycoprotein Reference proteome Signal | MKAGRAFGCL | MKAGRAFGCLFWALLYCVLYLDLVSGNSADDELMDFDFADSNDAAMEDWQLDDLEEAKKAEQAEKKLESNMLDFSVDLDEPEPEKQLPPFDWRERVLRNALAKALADEGLRQKFAEVLPILRMLSSQQRLALSALISAQMNAKKGHELKFEQVRMMFGNEKKLLLPIVFDIANLIKSSTRKYINLGSDLASSALYHTPINRREDDLTPEESQQDDQLGTIAVEVEPKKVSTEEVQLESLEDFFDEMGSEVLDPQMINEALTGDLHDNKTKTFKPENHGQRVRRSANEFVHKLTRSVPASVTEQQLLGGIAGRTIKLNTTA... | central nervous system formation innate immune response motor neuron axon guidance negative regulation of neuron apoptotic process regulation of neuronal synaptic plasticity in response to neurotrophin Toll signaling pathway extracellular region; extracellular space growth factor activity receptor ligand activity Toll ... |
potassium ion import across plasma membrane regulation of monoatomic ion transmembrane transport | monoatomic ion channel complex; plasma membrane | inward rectifier potassium channel activity | Homo sapiens | Cell membrane Disease variant Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MTAASRANPY | MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANE... | potassium ion import across plasma membrane regulation of monoatomic ion transmembrane transport monoatomic ion channel complex; plasma membrane inward rectifier potassium channel activity Homo sapiens Cell membrane Disease variant Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium transport Referenc... |
symbiont-mediated suppression of host canonical NF-kappaB cascade symbiont-mediated suppression of host defense-related programmed cell death | extracellular region; host cell cytoplasm | manganese ion binding protein-arginine N-acetylglucosaminyltransferase activity toxin activity | Escherichia coli O127:H6 | 3D-structure Glycoprotein Glycosyltransferase Host cytoplasm Manganese Metal-binding Reference proteome Secreted Toxin Transferase Virulence | MLSSLNVLQS | MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYSLEPIDERTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKKEFLNLENEHQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWFDFFRNLAILKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHNYNAFCDFIEFKHENIIPN... | symbiont-mediated suppression of host canonical NF-kappaB cascade symbiont-mediated suppression of host defense-related programmed cell death extracellular region; host cell cytoplasm manganese ion binding protein-arginine N-acetylglucosaminyltransferase activity toxin activity Escherichia coli O127:H6 3D-structure Gly... |
methylation symbiont-mediated suppression of host canonical NF-kappaB cascade | extracellular region; host cell nucleus | protein-cysteine methyltransferase activity toxin activity | Escherichia coli O127:H6 | Host nucleus Methyltransferase Reference proteome S-adenosyl-L-methionine Secreted Toxin Transferase Virulence | MINPVTNTQG | MINPVTNTQGVSPINTKYAEHVVKNIYPKIKHDYFNESPNIYDKKYISGITRGVAELKQEEFVNEKARRFSYMKTMYSVCPEAFEPISRNEASTPEGSWLTVISGKRPMGQFSVDSLYNPDLHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQRANRFIELYNIKRDIMQELNYELPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINNKLSKIE | methylation symbiont-mediated suppression of host canonical NF-kappaB cascade extracellular region; host cell nucleus protein-cysteine methyltransferase activity toxin activity Escherichia coli O127:H6 Host nucleus Methyltransferase Reference proteome S-adenosyl-L-methionine Secreted Toxin Transferase Virulence MINPVTN... |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity | Pseudomonas aeruginosa | Cytoplasm DNA damage DNA repair Hydrolase Stress response | MSNERDTSRT | MSNERDTSRTPTPDHAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYKGGKKVLMIGTDERYILMQNGSMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSIYAKYLPKLKAPQKLADLLEQAVADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKDRYIITLCHGPACLLAPAVEEKPEDYPFKDYEICVFPDALDTGANLEIGYMPGPLPWLVGENLQKLGVKILNKGITGQVHRDRKLLTGDSPLASNNLGKLAAKTLLEAFAR | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity Pseudomonas aeruginosa Cytoplasm DNA damage DNA repair Hydrolase Stress response MSNERDTSRT MSNERDTSRTPTPDHAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYKGGKKVLMIGTDERYILMQNGSMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSIYAKYLPKLKAPQKL... |
cell fate commitment determination of adult lifespan lysosome organization negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to osmotic stress response to oxidative stress | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding zinc ion binding | Caenorhabditis elegans | Alternative splicing Metal-binding Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | METANYYLPS | METANYYLPSPPYSSTSSSDSRESRMNTPIPTTYSEENVNSLFHLMPDNTDQWMTSQKNFWQEGSPSSSEYLHQQAVQPSQQARLPGISNFMKDSQLSVKPAAYYCSPTMNDYRVEKVANTLLDPYVQLDQPTYADFTNAQVLNHQQEMLQMNFPTPLSTSYMNTAQVTQTHQMPFNIFELNLSNFATFQPACDTPLPLLNSSPTHPYTTMSNFTPPPQDPLVAEPKPMKKRMAAVQCHQNSICSNCKTRETTLWRRNGEGGVECNACNLYFRKNNRKRPLSLRKDGIMKRNRRPRNESPNSAIRNTHQRHGHAAAC | cell fate commitment determination of adult lifespan lysosome organization negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to osmotic stress response to oxidative stress nucleus DNA-binding tran... |
anterior/posterior axis specification cellular response to retinoic acid ectodermal placode formation negative regulation of DNA-binding transcription factor activity negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II | nucleus | transcription coregulator activity | Xenopus laevis | Developmental protein Nucleus Reference proteome Repressor Transcription Transcription regulation | MDSSQYMLKA | MDSSQYMLKATLTQMCLCSRGVRNVHSEHPQQQDSSLTLWRPWLLGAGDRELDGQQRRSGEADGVPTNTGPKGALGFQHPVRLYMPKSKTSEYLQHMGRKVLASFPVQATIHFYNDDSDSEEEDEEEEMEFYNYYQNCAANGVDSSRGSSDNYSVQGGPKRNIGSHAGSA | anterior/posterior axis specification cellular response to retinoic acid ectodermal placode formation negative regulation of DNA-binding transcription factor activity negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nucleus transcription coregulator activity X... |
cAMP metabolic process cGMP metabolic process male mating behavior sexual reproduction signal transduction | extracellular space | 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity calmodulin binding calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity metal ion binding | Drosophila melanogaster | Alternative splicing Behavior cAMP cGMP Hydrolase Magnesium Metal-binding Reference proteome Zinc | MQPSSPNATN | MQPSSPNATNYLADNIQISSANLSQTEMVVGRDSADYTAMHSINVGVGNSFLRGDTDIPQESGHSFETPSNMSFTAGQWDTESLPPVDTPDALNKAAGRIRSLLRRMDHETVAYEDMQRNLHYAARVLEAVFIDESREGCNGNCKNLNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGAGAGVTPGADNQDSIESRTKGVSQAPQTHSGPTGPPSNTSSETIAQPAPKLQPALETVRESVMEESPSKDPGDKGPPPPASTSTLTSQTTTSSSATAEPSAKAAESQAGSAGSSGSCSNPAAVHRQRRLRTPTWARSMSTN... | cAMP metabolic process cGMP metabolic process male mating behavior sexual reproduction signal transduction extracellular space 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity calmodulin binding calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity metal ion binding Dro... |
intracellular pH reduction positive regulation of canonical NF-kappaB signal transduction protein transport T cell differentiation | Golgi cisterna membrane; Golgi membrane; Golgi-associated vesicle membrane; monoatomic ion channel complex | voltage-gated monoatomic anion channel activity | Homo sapiens | Alternative splicing Glycoprotein Golgi apparatus Ion channel Ion transport Membrane Protein transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MSFLIDSSIM | MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVT... | intracellular pH reduction positive regulation of canonical NF-kappaB signal transduction protein transport T cell differentiation Golgi cisterna membrane; Golgi membrane; Golgi-associated vesicle membrane; monoatomic ion channel complex voltage-gated monoatomic anion channel activity Homo sapiens Alternative splicing ... |
negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of activin receptor signaling pathway transcription by RNA polymerase II | nucleus; transcription regulator complex | DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding SMAD binding transcription cis-regulatory region binding | Xenopus laevis | Activator Developmental protein DNA-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation | MALAGKQYEG | MALAGKQYEGSLNNSRPNLWPSSIPGGKNEIITSLVTALDSMCTALSKLNTEVACIALHEESAFVVGTEKGRCFLNSRKELQADFQRFCIGAHKKDQENEVKRRNRDGIQNIQHVPLGPTSDIYLLRKMVEEIFEVLYSEALGKSNIVPVPYVKVMKEPGSVVVLGLPDGISFRKPAEYDLKSLMLILKHSHNIRFKLRIPTEESIREPKSCSELNSPPTSATKVIPETSQCHRLPIQEHPSSASNFPYSVSQPNQISLEPKQEVHSNMLGTNAVNQMLVQRPSAENNHDLSDCCGQQSPVAGSSLRQNVLASKHLLFSI... | negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of activin receptor signaling pathway transcription by RNA polymerase II nucleus; transcrip... |
G2/M transition of mitotic cell cycle oocyte maturation protein autophosphorylation regulation of lymphocyte migration | plasma membrane | ATP binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity | Xenopus laevis | ATP-binding Cell cycle Cell membrane Coiled coil Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MAFANFRRIL | MAFANFRRILRLPNFEKKRLREYEHVRRDVDPNQVWEIIGELGDGAFGKVYKAKNRETGILAAAKVIETKNEEELEDYMVEIEILATCNHHFIVKLLGAFYWEGKLWIMIEFCPGGAVDAVMLELDRGLKEPEIKTICRQMLEALAYLHSMKIIHRDLKAGNVLLTLDGDIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSEPPTLSSLSKWSPEFHSFLKTALDKNPETRPSAAQLLEHPFVKKASGNKPLRDLVAEAKAEVLDEIEE... | G2/M transition of mitotic cell cycle oocyte maturation protein autophosphorylation regulation of lymphocyte migration plasma membrane ATP binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity Xenopus laevis ATP-binding Cell cycle Cell membrane Coiled coil Kin... |
cartilage development chondrocyte differentiation gonadal mesoderm development growth plate cartilage chondrocyte growth negative regulation of canonical Wnt signaling pathway negative regulation of fatty acid oxidation negative regulation of osteoblast differentiation neural crest formation otic placode formation posi... | cytoplasm; nucleus | DNA binding sequence-specific DNA binding ubiquitin-like protein ligase binding | Xenopus laevis | Activator Chondrogenesis Cytoplasm Developmental protein Differentiation DNA-binding Gonadal differentiation Isopeptide bond Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation | MNLLDPFMKM | MNLLDPFMKMTEEQDKCMSGAPSPTMSDDSAGSPCPSGSGSDTENTRPQENTFPKGDQELKKETEDEKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQTEQEDGAEQTHISPNAIFKALQADSPHSSSSMSEVHSPGEHSGQSQGPPTPPTTPKTDIQPGKPDLKREGRPLQENGRQPPHIDFRDVDIGELSSEVISTIETFDVNEFDQYLPPNGHPGVGSTQASYTGSYGI... | cartilage development chondrocyte differentiation gonadal mesoderm development growth plate cartilage chondrocyte growth negative regulation of canonical Wnt signaling pathway negative regulation of fatty acid oxidation negative regulation of osteoblast differentiation neural crest formation otic placode formation posi... |
response to estrogen thyroid hormone transport | extracellular region; protein-containing complex | hormone activity identical protein binding thyroid hormone binding | Xenopus laevis | Direct protein sequencing Glycoprotein Hormone Reference proteome Secreted Signal Sulfation Thyroid hormone Transport | MASFKSFLLL | MASFKSFLLLALLAIVSEAAPPGHASHGEADSKCPLMVKVLDAVRGIPAANLLVNVFRQTESGKWEQITSGKTTELGEIHNLTTDEQFTEGVYKIEFATKAFWGKLGLSPFHEYVDVVFTANDAGHRHYTIAVLLTPYSFSSTAIVSEPHDDL | response to estrogen thyroid hormone transport extracellular region; protein-containing complex hormone activity identical protein binding thyroid hormone binding Xenopus laevis Direct protein sequencing Glycoprotein Hormone Reference proteome Secreted Signal Sulfation Thyroid hormone Transport MASFKSFLLL MASFKSFLLLALL... |
glomus development kidney vasculature development negative regulation of pronephric nephron tubule development negative regulation of transcription by RNA polymerase II negative regulation of Wnt signaling pathway pronephros development regulation of transcription by RNA polymerase II specification of pronephric proxim... | cytoplasm; nuclear speck | double-stranded methylated DNA binding hemi-methylated DNA-binding RNA binding sequence-specific DNA binding zinc ion binding | Xenopus laevis | Alternative splicing Cytoplasm Developmental protein DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat RNA editing RNA-binding Transcription Transcription regulation Tumor suppressor Ubl conjugation Wnt signaling pathway Zinc Zinc-finger | MGSDVRDMNL | MGSDVRDMNLLPPVSSLSGNSSCNMPVSSSAQWAPVLDFPPGAPYSSLTPHSFIKQEPTWNPDPHEDQCLSAFTVHFSGQFTGTAGACRYGPFGAPTPSQATTGQARMFSNAPYLSNCLDNQQGMRNQGYSAVAFDGTPSYGHTPSHHTSQFTNHSFKHEDPLSQQTSLGEQQYSVPPPVYGCHTPTDTCTGSQALLLRTPYNSDNLYPMTSQLDCMTWNQMNLGSSLKSHGTSYENDSHSSPMLYNCGGQYRIHTHGVFRGIQDVRRVPGVTPAIVRSTEANEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQC... | glomus development kidney vasculature development negative regulation of pronephric nephron tubule development negative regulation of transcription by RNA polymerase II negative regulation of Wnt signaling pathway pronephros development regulation of transcription by RNA polymerase II specification of pronephric proxim... |
commitment of multipotent stem cells to neuronal lineage in forebrain DNA damage response eye development fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment heart development protein palmitoylation telencephalon development | endoplasmic reticulum membrane; Golgi apparatus | palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity | Danio rerio | Acyltransferase Endoplasmic reticulum Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MHPCSSVLHL | MHPCSSVLHLLLRCMRGCCRHTRSRVPRRLRRHVSYIRLIFKSLYFNSLTNSDVVTDSILEPVFWMVEVVTRWFGMVFVFLVVALTSSVVFIAYFCLLPLVLHTYSPGWMIWHICYGHWNLVMIVFHYYKATKTPPGYPPKMKTDVPFVSVCKKCIIPKPARSHHCGICKTCILKMDHHCPWLNNCVGHFNHRYFFSFCLFLTLGCMYCSVSGRHLFIDAYNTIDQLKHLEAEKQGVPVTGIGLLIGIVPSAGVAGKAVQVAQEVSQPPYTYKDRMFHKSVIYMWVLTSTVSVALGALTLWHALLITRGETSIERHINGK... | commitment of multipotent stem cells to neuronal lineage in forebrain DNA damage response eye development fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment heart development protein palmitoylation telencephalon development endoplasmic reticulum membrane; Golgi apparatus pa... |
collagen fibril organization embryonic viscerocranium morphogenesis fibronectin fibril organization inflammatory response lung development negative regulation of T-helper 17 cell lineage commitment peptidyl-lysine oxidation positive regulation of integrin-mediated signaling pathway roof of mouth development somite deve... | collagen-containing extracellular matrix; cytoplasm; extracellular space; membrane; nucleus | copper ion binding fibronectin binding protein-lysine 6-oxidase activity | Danio rerio | Alternative splicing Copper Cytoplasm Disulfide bond Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Secreted Signal TPQ | MELHQWCRHI | MELHQWCRHIIVFLLNVWIPSCFAQTTPPARSSPTPTPQTADNPDSLKFRLSGFPRKHNEGRIEVFYKGEWGTICDDDFSLANAHVLCRQLGFVSATGWTHSAKYGKGAGKIWLDNVQCSGSERSVSVCKSRGWGNSDCTHDEDAGVICKDERLPGFVDSNVIEVQVDENRVEEVRLRPVFTTATKRMPVTEGVVEVKNKDGWAQICDIGWTPKNTHVVCGMMGFPHEKKVNKNFYKLYAERQKNFFLVHSVACLGTEVHLAACPLEFNYGNATESCPGGMPAVVSCVPGPLYTQSPTMKKKLKMPPTTRLKGGAKYGEG... | collagen fibril organization embryonic viscerocranium morphogenesis fibronectin fibril organization inflammatory response lung development negative regulation of T-helper 17 cell lineage commitment peptidyl-lysine oxidation positive regulation of integrin-mediated signaling pathway roof of mouth development somite deve... |
protein homotrimerization proteolysis | extracellular space | IgE binding metalloendopeptidase activity nutrient reservoir activity zinc ion binding | Oryza sativa subsp. indica | Allergen Direct protein sequencing Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Seed storage protein Signal Storage protein Zinc | MAKKKTSSSM | MAKKKTSSSMARSQLAALLISLCFLSLASNAVGWSRRGEREEEDERRRHGGEGGRPYHFGEESFRHWTRTRHGRFSVLERFPDEQVVGAAVGGYRVAVLEAAPRAFLQPSHYDADEVFYVKEGEGVIVLLREGRKESFCVREGDAMVIPAGAIVYSANTHSSKWFRVVMLLNPVSTPGHFEEYFPVGGDRPESFFSAFSDDVLQAAFNTRREELEKVFERQREGGEITTAPEEQIRELSKSCSRGGGGGSGSEWEIKPSSLTGKSPYFSNNHGKLFELTGDECRHLKKLDLQIGLANITRGSMIAPNYNTRATKLAVVLQ... | protein homotrimerization proteolysis extracellular space IgE binding metalloendopeptidase activity nutrient reservoir activity zinc ion binding Oryza sativa subsp. indica Allergen Direct protein sequencing Glycoprotein Hydrolase Metal-binding Metalloprotease Protease Reference proteome Secreted Seed storage protein Si... |
auxin biosynthetic process regulation of leaf development regulation of root development | endoplasmic reticulum | flavin adenine dinucleotide binding indole-3-pyruvate monooxygenase activity N,N-dimethylaniline monooxygenase activity NADP binding | Oryza sativa subsp. indica | Endoplasmic reticulum FAD Flavoprotein Monooxygenase NADP Oxidoreductase Reference proteome | MQGQQKQNAG | MQGQQKQNAGGGGGDNASPCIVLDGPIIVGAGPSGLAVAATLRQHGAPFTVVERSGGVADLWTNRTYDRLRLHLPKVFCELPHVAFPPDFPTYPTKHDFLRYLHSYAARFAIAPLLRRTVTRAWYDHPASLWRVTTTTTSSSATSVITEYASPWLVVASGENAEVVVPKVKGRERFAGEALHSSEYRSGERFRGMRVLVVGCGNSGMEMCLDLCEHGAMPFMSVRSGVHVLPREMFGASTFGIAMKLLRWLPIKMVDRFLLLVARMVLGDTEKYGLKRPKLGPLEIKNITGKSPVLDVGAWSLIKSGNIKIVPEVESFSG... | auxin biosynthetic process regulation of leaf development regulation of root development endoplasmic reticulum flavin adenine dinucleotide binding indole-3-pyruvate monooxygenase activity N,N-dimethylaniline monooxygenase activity NADP binding Oryza sativa subsp. indica Endoplasmic reticulum FAD Flavoprotein Monooxygen... |
regulation of floral organ abscission regulation of flower development regulation of seed development response to cold seed abscission | nucleus; transcription regulator complex | DNA-binding transcription factor activity transcription cis-regulatory region binding | Oryza sativa subsp. indica | DNA-binding Nucleus Reference proteome Repeat Transcription Transcription regulation | MWDLNDSPAA | MWDLNDSPAAEAAPPPLSPSADDSGASSSSAAAVVEIPDDADDDSAAVVVVTRQFFPPAVPGGGGDPAPGNARAGWLRLAGAAPPVAATGPAASAAVSKKSRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFSLEDYEDDLKQMSNLTKEEFVHVLRRQSTGFPRGSSKYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEEEAARAYDRAAIKCNGKDAVTNFDPSIYAGEFEPPAAATGDAAEHNLDLSLGSSAGSKRGNVDGGGDDEITGGGGGGTGSDQRV... | regulation of floral organ abscission regulation of flower development regulation of seed development response to cold seed abscission nucleus; transcription regulator complex DNA-binding transcription factor activity transcription cis-regulatory region binding Oryza sativa subsp. indica DNA-binding Nucleus Reference p... |
brassinosteroid mediated signaling pathway phosphorylation | plasma membrane | ATP binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity | Oryza sativa subsp. indica | ATP-binding Cell membrane Glycoprotein Kinase Leucine-rich repeat Membrane Nucleotide-binding Receptor Reference proteome Repeat Serine/threonine-protein kinase Signal Transferase Transmembrane Transmembrane helix | MAAPRWAVWA | MAAPRWAVWAVLLLRLLVPAARVLANMEGDALHSLRTNLVDPNNVLQSWDPTLVNPCTWFHVTCNNDNSVIRVDLGNAALSGTLVPQLGQLKNLQYLELYSNNISGTIPSELGNLTNLVSLDLYLNNFTGPIPDSLGNLLKLRFLRLNNNSLSGSIPKSLTAITALQVLDLSNNNLSGEVPSTGSFSLFTPISFANNPSLCGPGTTKPCPGAPPFSPPPPYNPPTPVQSPGSSSSTGAIAGGVAAGAALLFAIPAIGFAWYRRRKPQEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRL... | brassinosteroid mediated signaling pathway phosphorylation plasma membrane ATP binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity Oryza sativa subsp. indica ATP-binding Cell membrane Glycoprotein Kinase Leucine-rich repeat Membrane Nucleotide-binding Recept... |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Shewanella piezotolerans | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MIYQSPTIEV | MIYQSPTIEVELLEDNIAHLCFNAQGSVNKFDRETIDSLNAALDSIKQNNSIKGLMLTSAKPAFIVGADITEFLGLFAEEDAVLLSWLEEANVVFNKLEDLPFPTISAINGFALGAGCETILATDFRVADTTARIGLPETKLGIIPGFGGTVRLPRVVGTDNALEWITSGKDQRPEAALNVGAIDALVAPEQLQSAALKMLKDAIAEKLDWQTRRAKKLAPLTLPKLEAMMSFATAKGMVFKVAGKHYPAPMAVVSVIEKAAQLDRAGALKVEHQAFLKLAKTEVAQSLIGIFLNDQLVKGKAKKAGKLAKKVNSAAVLG... | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Shewanella piezotolerans Fatty acid metabolism Isomerase Lipid degradation Lip... |
ribosome biogenesis | cytoplasm | GTP binding GTPase activity magnesium ion binding | Caulobacter vibrioides | Cytoplasm Direct protein sequencing GTP-binding Hydrolase Magnesium Metal-binding Nucleotide-binding Reference proteome | MKFLDQCKIY | MKFLDQCKIYIRSGNGGGGSVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRARHGAAGEDVVLKVPVGTEVLEEDKETLIADLDHAGMRLLLAKGGNGGWGNLHFKGPVNQAPKYANPGQEGEERWIWLRLKLIADVGLVGLPNAGKSTFLAAASAAKPKIADYPFTTLTPNLGVVDLSSSERFVLADIPGLIEGASEGAGLGTRFLGHVERSATLIHLIDATQDDVAGAYETIRGELEAYGDELADKAEILALNKIDALDEETLAEKVAELEAVSGIKPRLVSGVSGQGVTELL... | ribosome biogenesis cytoplasm GTP binding GTPase activity magnesium ion binding Caulobacter vibrioides Cytoplasm Direct protein sequencing GTP-binding Hydrolase Magnesium Metal-binding Nucleotide-binding Reference proteome MKFLDQCKIY MKFLDQCKIYIRSGNGGGGSVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRARHGAAGED... |
cell cycle cell differentiation phosphorelay signal transduction system | cytoplasm | diguanylate cyclase activity GTP binding metal ion binding | Caulobacter vibrioides | 3D-structure Cell cycle Cytoplasm Differentiation GTP-binding Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Transducer Transferase Two-component regulatory system | MSARILVVDD | MSARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDIILLDVMMPGMDGFTVCRKLKDDPTTRHIPVVLITALDGRGDRIQGLESGASDFLTKPIDDVMLFARVRSLTRFKLVIDELRQREASGRRMGVIAGAAARLDGLGGRVLIVDDNERQAQRVAAELGVEHRPVIESDPEKAKISAGGPVDLVIVNAAAKNFDGLRFTAALRSEERTRQLPVLAMVDPDDRGRMVKALEIGVNDILSRPIDPQELSARVKTQIQRKRYTDYLRNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDP... | cell cycle cell differentiation phosphorelay signal transduction system cytoplasm diguanylate cyclase activity GTP binding metal ion binding Caulobacter vibrioides 3D-structure Cell cycle Cytoplasm Differentiation GTP-binding Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Transduce... |
cell cycle cell division protein catabolic process proteolysis | plasma membrane | ATP binding ATP hydrolysis activity ATP-dependent peptidase activity metalloendopeptidase activity zinc ion binding | Caulobacter vibrioides | ATP-binding Cell cycle Cell division Cell inner membrane Cell membrane Hydrolase Membrane Metal-binding Metalloprotease Nucleotide-binding Protease Reference proteome Stress response Transmembrane Transmembrane helix Zinc | MNFRNLAIWL | MNFRNLAIWLVIVAVLGGVFVVSQNSRTKSSSEISYSQLLKDVDAGKIKSAEIAGQTVLAKTADNKTLTVNAPMNSEELVNRMVAKNADVKFKSGSISFLAILVQLLPILLVVGVWLFLMRQMQGGAKGAMGFGKSKARLLTENKNRITFEDVAGVDEAKEELQEVVDFLKDPAKFQRLGGKIPKGALLVGPPGTGKTLIARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRHRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIILIAATNRPDVLDPALLRPGRFDRQVVVPN... | cell cycle cell division protein catabolic process proteolysis plasma membrane ATP binding ATP hydrolysis activity ATP-dependent peptidase activity metalloendopeptidase activity zinc ion binding Caulobacter vibrioides ATP-binding Cell cycle Cell division Cell inner membrane Cell membrane Hydrolase Membrane Metal-bindi... |
proteolysis | apical plasma membrane; extracellular space; plasma membrane; side of membrane | metallocarboxypeptidase activity zinc ion binding | Danio rerio | Carboxypeptidase Cell membrane Direct protein sequencing Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Zinc | MMQASITSIL | MMQASITSILVVLTLVAQDRLAGGLEHKSYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTTPKKAIWMDCGIHAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSPCHENSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLTIHSYGQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRDFARLIGIPYSFTFELRDEGQHGFILPEDQIQPTCQE... | proteolysis apical plasma membrane; extracellular space; plasma membrane; side of membrane metallocarboxypeptidase activity zinc ion binding Danio rerio Carboxypeptidase Cell membrane Direct protein sequencing Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Protease Reference prote... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Daboia russelii | Calcium Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Toxin Zinc Zymogen | MMQVLLVTIC | MMQVLLVTICLAVFPYHGSSIILESGNVNDYEVVYPQKVTAMPKEAVKQPEQKYEDAMQYKFEVNGEPVLLHLEKNKDLFSEDYSETHYSPDGREITTKPLVQDHCYYHGHIQNDAHSSASISACNGLKGHFKLRGEMYLIEPLKLSDSEAHAVYKYENVEKEDEALKMCGVTQTNWESDEPIKKASLLVATSERNRYFNPYSYVELIITVDHSMVTKYKNDLTAIRTWVFELVNTINEIFKYLYIRVPLVGLEIWKNRDLINVTSAANVTLDLFGEWRKSYLLPRKIHDNSQLLTAIDLNGLTIGMAYVSTMCQSKYSV... | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Daboia russelii Calcium Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Toxin Zinc Z... |
intraciliary transport | cytoplasm; cytoskeleton; intraciliary transport particle B; motile cilium | metal ion binding | Chlamydomonas reinhardtii | 3D-structure Calcium Cell projection Cilium Cytoplasm Cytoskeleton Direct protein sequencing Flagellum Metal-binding | MKDYAREENG | MKDYAREENGGLVVMASCSDERFPPENMLDGKDNTFWVTTGMFPQEFVLRLESCIRVSKITTLSLNVRKLAVEKCDQDKPDQFEKVFEVELANRGDRLQTEVHQVNIRAKYLKFILLQGHGEFATVNRVSVVGGDDDGGGYDEPGGGYGSMQRQPSMGYGGGGGSAATGFAADPGNAAAGGGGGFEDEF | intraciliary transport cytoplasm; cytoskeleton; intraciliary transport particle B; motile cilium metal ion binding Chlamydomonas reinhardtii 3D-structure Calcium Cell projection Cilium Cytoplasm Cytoskeleton Direct protein sequencing Flagellum Metal-binding MKDYAREENG MKDYAREENGGLVVMASCSDERFPPENMLDGKDNTFWVTTGMFPQEFVLRL... |
methylation sterol biosynthetic process | endoplasmic reticulum membrane | heme binding iron ion binding methyltransferase activity sterol 14-demethylase activity | Aspergillus flavus | Endoplasmic reticulum Glycoprotein Heme Iron Membrane Metal-binding Methyltransferase Monooxygenase Oxidoreductase Transferase Transmembrane Transmembrane helix | MIFSRSMASF | MIFSRSMASFTLVSAYAAAGLLAIIVLNLLRQLLFRNKTDPPLVFHWIPFLGSTVTYGMDPYAFFFSCRQKYGDIFTFILLGRKITVYLGIQGNEFILNGKLKDVNAEEIYSPLTTPVFGSDIVYDCPNSKLMEQKKFIKFGLTQAALESHVPLIEKEVLDYLKTSPNFKGTSGRVEITDAMAEITIFTAGRALQGEEVRKKLTAEFADLYHDLDRGFTPINFMLPWAPLPRNRKRDAAHARMREIYMDIINERRKNPDRETSDMIWNLMHCTYKNGQPLPDKEIAHMMITLLMAGQHSSSSISSWIMLRLASEPAVMEE... | methylation sterol biosynthetic process endoplasmic reticulum membrane heme binding iron ion binding methyltransferase activity sterol 14-demethylase activity Aspergillus flavus Endoplasmic reticulum Glycoprotein Heme Iron Membrane Metal-binding Methyltransferase Monooxygenase Oxidoreductase Transferase Transmembrane T... |
methylation sterol biosynthetic process | endoplasmic reticulum membrane | heme binding iron ion binding methyltransferase activity sterol 14-demethylase activity | Aspergillus flavus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Methyltransferase Monooxygenase Oxidoreductase Transferase Transmembrane Transmembrane helix | MGILAVILDS | MGILAVILDSVCERCSGSSLWMLSTVALLSILVVSVVINVLRQLLFKNYKEPPLVFHWFPFIGSTISYGMDPYRFFFNCREKYGDIFTFVLLGKKTTVYLGTKGNDFILNGKLRDVCAEEVYSPLTTPVFGRHVVYDCPNAKLMEQKKGPNGVFDVCKTIAEITIYTASRSLQGKEVRSRFDSTFAELYHDLDMGFAPINFMLPWAPLPHNRKRDAAQKRMTETYMEIIKERRKAGSKKDSEDMVWNLMSCMYKDGTPVPDEEIAHMMIALLMAGQHSSSSTAAWIVLHLAASPEITEELYQEQLRILGHDMPPLTYENL... | methylation sterol biosynthetic process endoplasmic reticulum membrane heme binding iron ion binding methyltransferase activity sterol 14-demethylase activity Aspergillus flavus Endoplasmic reticulum Heme Iron Membrane Metal-binding Methyltransferase Monooxygenase Oxidoreductase Transferase Transmembrane Transmembrane ... |
exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protei... | CBF3 complex; kinetochore; nuclear SCF ubiquitin ligase complex; RAVE complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex | DNA replication origin binding ubiquitin protein ligase activity | Aspergillus flavus | Ubl conjugation pathway | MATPTLTFTS | MATPTLTFTSSDGVDIPVERDVAERSQLIKNMLEDLGETGEPIPIPNVNEAVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKGLLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEDR | exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protei... |
sterol biosynthetic process | endoplasmic reticulum membrane | heme binding iron ion binding sterol 14-demethylase activity | Aspergillus flavus | Endoplasmic reticulum Glycoprotein Heme Iron Membrane Metal-binding Monooxygenase Oxidoreductase Transmembrane Transmembrane helix | MSWPRIGAYA | MSWPRIGAYALLAFVAIMALNVTYQFLFRMLNKTRPPLVFHWIPFIGSTIHYGMDPYGFFFSCREKYGDIFTFILLGRPTTVYLGTQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVVYDCPNSKLIEQKKFIKFGLSQAALEAHVPLIEKEVEDYLAMSPNFHGTSGEVDIPAAMAEITIFTAGSALQGEEVRSKLTTEFAVLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMRSIYIDIINKRRNAGDNVPEKLDMIGNLMQCTYKNGQPLPDKEIAHIMITLLMAGQHSSSSISSWIMLRLASQPAVVEELYQ... | sterol biosynthetic process endoplasmic reticulum membrane heme binding iron ion binding sterol 14-demethylase activity Aspergillus flavus Endoplasmic reticulum Glycoprotein Heme Iron Membrane Metal-binding Monooxygenase Oxidoreductase Transmembrane Transmembrane helix MSWPRIGAYA MSWPRIGAYALLAFVAIMALNVTYQFLFRMLNKTRPPLV... |
epithelial cell-cell adhesion heart development positive regulation of locomotion positive regulation of receptor recycling regulation of cell shape regulation of GTPase activity regulation of membrane potential response to ischemia skeletal muscle tissue development striated muscle cell differentiation substrate adhes... | bicellular tight junction; caveola; lateral plasma membrane; membrane; plasma membrane; sarcolemma | cAMP binding structural molecule activity | Sus scrofa | Alternative splicing cAMP cAMP-binding Cell adhesion Cell junction Cell membrane Developmental protein Glycoprotein Membrane Nucleotide-binding Phosphoprotein Reference proteome Tight junction Transmembrane Transmembrane helix | MNYTESSPLA | MNYTESSPLAESTAIGFTPELGSITPVPSNETTCENWREIHHLVFHVANVFFAIGLVLPTTLHLHMILLRGMLTIGCTLYIVWATLYRCALDIMIWNSVFLGINVLHLSYLLYKKRPVKIEKELKGIYQRLFEPLRVPPDLFKRLTGQFCMIQTLKKGQAYAAEDKTSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLESEPFLYEVFRYLIGKDITNKLYSLNDPTLNDKTIKKLDHQLSLCTQLSMLEMRNSIVSTSDSEDGLHQFLRGTSSVSSLY... | epithelial cell-cell adhesion heart development positive regulation of locomotion positive regulation of receptor recycling regulation of cell shape regulation of GTPase activity regulation of membrane potential response to ischemia skeletal muscle tissue development striated muscle cell differentiation substrate adhes... |
chromatin remodeling chromosome organization DNA damage response G1/S transition of mitotic cell cycle intracellular iron ion homeostasis MAPK cascade negative regulation of apoptotic process negative regulation of cell division negative regulation of monocyte differentiation negative regulation of stress-activated MAP... | nucleolus; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding protein dimerization activity protein-containing complex binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Macaca mulatta | Acetylation Activator Alternative initiation DNA-binding Glycoprotein Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MDFFPVVENQ | MDFFPVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSPRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASPDSSAFSPSSDSLLSSTESSPQASPEPLVLHEETPPTTSSDSEEEQEEEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTH... | chromatin remodeling chromosome organization DNA damage response G1/S transition of mitotic cell cycle intracellular iron ion homeostasis MAPK cascade negative regulation of apoptotic process negative regulation of cell division negative regulation of monocyte differentiation negative regulation of stress-activated MAP... |
activation of innate immune response autophagosome assembly cGAS/STING signaling pathway defense response to virus innate immune response positive regulation of interferon-beta production positive regulation of macroautophagy positive regulation of type I interferon production reticulophagy | autophagosome; autophagosome membrane; cytoplasm; cytoplasmic vesicle; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi membrane; mitochondrial outer membrane; perinuclear region of cytoplasm; plasma membrane | 2',3'-cyclic GMP-AMP binding cyclic-di-GMP binding protein homodimerization activity proton channel activity signaling adaptor activity | Sus scrofa | 3D-structure Autophagy Cell membrane Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Golgi apparatus Host-virus interaction Immunity Innate immunity Isopeptide bond Lipoprotein Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transmembrane Transmembr... | MPYSSLHPSI | MPYSSLHPSIPQPRGLRAQVAALVLLGACLVALWGLGELPEYTLRWLVLHLASQQIGLLVKGLCSLAEELCHVHSRYQSSYWRAARACLGCPIRCGALLLLSCYFYFSIRDKAGLPLPWMLALLGLSQALNILLGLQHLAPAEVSAICEKRNFNVAHGLAWSYYIGYLRLILPGLRARIQAYNQRHKNVLGGIGNHRLHILFPLDCGVPDDLSVADPNIRFLHELPQQSADRAGIKGRVYTNSIYELLENGQPAGVCVLGYATPLQTLFAMSQDGRAGFSREDRLEQAKLFCRTLEDILADAPEAQNNCRLIVYQEPTEG... | activation of innate immune response autophagosome assembly cGAS/STING signaling pathway defense response to virus innate immune response positive regulation of interferon-beta production positive regulation of macroautophagy positive regulation of type I interferon production reticulophagy autophagosome; autophagosome... |
RNA catabolic process rRNA catabolic process | endoplasmic reticulum lumen; extracellular region; lysosomal lumen | ribonuclease T2 activity RNA binding RNA endonuclease activity | Danio rerio | Disulfide bond Endonuclease Endoplasmic reticulum Glycoprotein Hydrolase Lyase Lysosome Nuclease Reference proteome Secreted Signal | MRFIAFAVIF | MRFIAFAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHCKTDFSYWTLHGLWPNTGVRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPSEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEKSSEDTWSNDLPTVPVSGQSGLSVCDHSMPVYYPPVQA | RNA catabolic process rRNA catabolic process endoplasmic reticulum lumen; extracellular region; lysosomal lumen ribonuclease T2 activity RNA binding RNA endonuclease activity Danio rerio Disulfide bond Endonuclease Endoplasmic reticulum Glycoprotein Hydrolase Lyase Lysosome Nuclease Reference proteome Secreted Signal ... |
xylan catabolic process | extracellular region | acetylxylan esterase activity endo-1,4-beta-xylanase activity | Neocallimastix patriciarum | Carbohydrate metabolism Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Repeat Secreted Signal Xylan degradation | MRLGVALSTI | MRLGVALSTIAVLLTATSARNLDKRQWGWPNFGGGNGGNGGNGGKTINDYKREQGAGRDIHVYAPSNLAPNSPLLLSLHGMDQDPNYQQSNTHWETLADSEGFVVVYPRGGTGMSTWDIQGTKDTQWVSQIIDQMKKEYNIDTKRVYLSGFSMGGMFTYHAMSQIANKIAAFAPCSGPNVFGASKAQRPVPIFHVHGTNDDVLNYQQVEGFLKNYRDQFHCPSQADTKTNYPNRENPNATLYTWGPCDKGVYIKHLKLQGRGHSPSSADIQDIWDFVSQWTVDGPVSASGNGGGNTTPTNPSTGGNGNGNGGGNTTPTNP... | xylan catabolic process extracellular region acetylxylan esterase activity endo-1,4-beta-xylanase activity Neocallimastix patriciarum Carbohydrate metabolism Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Repeat Secreted Signal Xylan degradation MRLGVALSTI MRLGVALSTIAVLLTATSARNLDKRQWGWPNFGGGNGGNGGNGGKTIN... |
tRNA-guanine transglycosylation | cytoplasm; mitochondrial outer membrane; mitochondrion; protein-containing complex; transferase complex | protein heterodimerization activity protein homodimerization activity tRNA binding tRNA-guanosine(34) queuine transglycosylase activity zinc ion binding | Mus musculus | 3D-structure Alternative splicing Cytoplasm Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Reference proteome tRNA processing Zinc | MKLSLIKVVN | MKLSLIKVVNGCRLGKIQNLGKAGDCTVDIPGCLLYTRTGSAPHLTHQTLRNIHGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPVTPGPAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEASCAETTSIKRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGDPAVTETRLHLLSSVTAELPEDKPRLICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFTFDCQLNPEETLLQQNGIQEKIKGLDQAKKIE... | tRNA-guanine transglycosylation cytoplasm; mitochondrial outer membrane; mitochondrion; protein-containing complex; transferase complex protein heterodimerization activity protein homodimerization activity tRNA binding tRNA-guanosine(34) queuine transglycosylase activity zinc ion binding Mus musculus 3D-structure Alter... |
carbohydrate metabolic process circadian rhythm regulation of seed germination regulation of timing of transition from vegetative to reproductive phase | mitochondrion | glycopeptide alpha-N-acetylgalactosaminidase activity sucrose alpha-glucosidase activity | Arabidopsis thaliana | Carbohydrate metabolism Glycosidase Hydrolase Mitochondrion Phosphoprotein Reference proteome Transit peptide | MNSRSCICVS | MNSRSCICVSAMKPCCRFLISFRSSSLFGFSPPNSGKFINSSKLHCTKIDSRSIRSGIHCRRIVLDRNAFCDSDSISWGGGGSRVLRARGSSRGRGRGVLVIPHVASDFRNYSTSSLDSHVNDKSFESMFVKPLVFKEVEKTEGIPKRERGNVGGGKDANFGNVGVRKETERCLSQTEVEKEAWKLLRGAVVNYCGFPVGTVAANDPGDTQTLNYDQVFIRDFVPSAYAFMLDGEGEIVRNFLLHTLQLQSWEKTVDCHSPGPGLMPASFKVKSAPLEGNDGSFEEFLDPDFGGSAIGRVSPVDSGLWWIILLRAYGKLT... | carbohydrate metabolic process circadian rhythm regulation of seed germination regulation of timing of transition from vegetative to reproductive phase mitochondrion glycopeptide alpha-N-acetylgalactosaminidase activity sucrose alpha-glucosidase activity Arabidopsis thaliana Carbohydrate metabolism Glycosidase Hydrolas... |
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