Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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anatomical structure development axon guidance dendrite development larval development negative regulation of transcription by RNA polymerase II neuron fate specification positive regulation of axon extension regulation of neuron differentiation regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Developmental protein DNA-binding Homeobox Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MVDIAEAMPT | MVDIAEAMPTTASSLPSDEALRKFKCPECTKAFKFKHHLKEHIRIHSGEKPFECQQCHKRFSHSGSYSSHMSSKKCVQQASPSMVTPFNPYQLMMYRNIMLQLQTPQVSFLPSTAANNMDYMSLLQANLFQSLENGTSPTPTQEPSAPASPEPKIEVVDEPEVSSEVKTEVKTEVKTEDSVPEESITPAVSMSLSPAPEQNGNESMNNGGSGSDGKSSPDWRPLRSRSFLNDSQVAVLQNHFKRNPFPSKYELSAVAEQIGVNKRVVQVWFQNTRAKERRSNRLPSMPRGSVASAAAAAATSPTVWQTPVQLMAAWASQF... | anatomical structure development axon guidance dendrite development larval development negative regulation of transcription by RNA polymerase II neuron fate specification positive regulation of axon extension regulation of neuron differentiation regulation of transcription by RNA polymerase II nucleus DNA-binding trans... |
cellular response to hypoxia regulation of protein localization response to hypoxia | axon; cytoplasm; dendrite; nucleus | ferrous iron binding hypoxia-inducible factor-proline dioxygenase activity L-ascorbic acid binding peptidyl-proline 4-dioxygenase activity | Caenorhabditis elegans | Alternative splicing Cell projection Cytoplasm Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteome Vitamin C Zinc Zinc-finger | MSSAPNDDCE | MSSAPNDDCEIDKGTPSTASLFTTLMLSQPSSSTAVLQCTYCGSSCTSSQLQTCLFCGTVAYCSKEHQQLDWLTHKMICKSLQTSGMVPSNLMPQAAPAVMAPIPPTVSFDDPALTTSLLLSLQNNPILNQTISNFPPTFSITSKTEPEPSIPIQIPQRISSTSTVPFSSEGSAFKPYRNTHVFNSISSESMSSMCTSHEASLEHMSSASLAMFPTSSTAQSDISRLAQVLSLAGDSPASLALVTTSVPSTASTATIPPPATTTSSATSSGKSETITVGKEKIIQTDDPDIQIIETEGGSKPTVSRTRKRPTPSNSADPK... | cellular response to hypoxia regulation of protein localization response to hypoxia axon; cytoplasm; dendrite; nucleus ferrous iron binding hypoxia-inducible factor-proline dioxygenase activity L-ascorbic acid binding peptidyl-proline 4-dioxygenase activity Caenorhabditis elegansAlternative splicing Cell projection Cyt... |
apoptotic cell clearance apoptotic DNA fragmentation exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) histone mRNA catabolic process nuclear polyadenylation-dependent antisense transcript catabolic process nuclear polyadenylation-dependent ... | exosome (RNase complex); nuclear exosome (RNase complex); nucleolus; nucleoplasm | 3'-5'-RNA exonuclease activity nucleotide binding single-stranded RNA binding | Caenorhabditis elegans | Alternative splicing Apoptosis Exonuclease Exosome Hydrolase Nuclease Nucleus Reference proteome rRNA processing | MSGEESMPDE | MSGEESMPDEEQKQSEEEEEMIRKRTLAMRKKVEEIMRNGAGLVRESNGLPKAGADYELYNSYPTFNTFMKRSEQRLNALMNKVTKSIGCAMRVPDVGSSVEHYTECVIEAQDNIAERAATLHEALKKAELDEIVKVPEFITKAAPTNRKTEAEVSAAMRTFSANIGTVLAEKFRERREEAAQMVVLEKPQKTYNISSDNSQAPFSSKLTVKHHAIEKRTGIVLHDDDESGRRDWISAETETEEEHPYIAEILHFKVPEAQLKSAECLKFTALKDTPLTMIDTKEKLEALTKTLNSVKEFAVDLEHHQMRSYLGLTCLIQ... | apoptotic cell clearance apoptotic DNA fragmentation exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) histone mRNA catabolic process nuclear polyadenylation-dependent antisense transcript catabolic process nuclear polyadenylation-dependent ... |
detection of stimulus involved in sensory perception | axon; cilium; cytosol; dendrite; neuronal cell body; nucleus; perikaryon; plasma membrane | calcium ion binding iron ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Caenorhabditis elegans | Alternative splicing Calcium Cell membrane Cell projection Hydrolase Lipoprotein Manganese Membrane Metal-binding Myristate Palmitate Reference proteome Repeat | MGCGPSSGRQ | MGCGPSSGRQNPSTELKKSTRATTTTTSSSQRNNYNDNNQNTSSSSGNKKESSSSSKQHSSKKSKKSNSKKNRSPSPQPQLTIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALSHYAKPSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHED... | detection of stimulus involved in sensory perception axon; cilium; cytosol; dendrite; neuronal cell body; nucleus; perikaryon; plasma membrane calcium ion binding iron ion binding manganese ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Caenorhabditis elegansAlternative splicing C... |
backward locomotion dorsal/ventral axon guidance inductive cell migration locomotion motor neuron axon guidance nematode male tail tip morphogenesis | extracellular region; extracellular space | cytokine activity growth factor activity signaling receptor binding transforming growth factor beta receptor binding | Caenorhabditis elegans | Glycoprotein Growth factor Neurogenesis Reference proteome Secreted Signal | MRRLPIVLLL | MRRLPIVLLLSVFSIANCAKVDVDLINETIRDLLHFKSSDPNVTSFHRSSHTLTEHMKNLYENFIDEDSNEDGNLVRAIEPAVGKFEGQEVLVFDVEGFDSHESIMRAELHFYLRRRDSFARRRSRQIRAKSVCVNEYCRQQTLKKIRVGGDENLEEYKVIWDATKSVFDSYHLDAKQAVFRITREHSKMRPYAEMIRKSTPFLVIYSKVNHTLDTVSVMKQTEQTKRKRRDLGNEELREYYNYNSIPLDNDDREPIKRKNGKKNSLSEEISSEDVWQGFGEETSREERERIANEELANDVRVVLLQNKNRCHKEGVLVS... | backward locomotion dorsal/ventral axon guidance inductive cell migration locomotion motor neuron axon guidance nematode male tail tip morphogenesis extracellular region; extracellular space cytokine activity growth factor activity signaling receptor binding transforming growth factor beta receptor binding Caenorhabdit... |
chromatin remodeling dauer exit defense response to other organism determination of adult lifespan negative regulation of protein localization to nucleus negative regulation of transcription by RNA polymerase II negative regulation of transcription by transcription factor localization positive regulation of transcripti... | histone methyltransferase complex; nucleus; transcription regulator complex | DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding transcription coactivator activity transcription coregulator binding transcription corepressor activity | Caenorhabditis elegans | Kelch repeat Nucleus Phosphoprotein Reference proteome Repeat | MDEDVGLEAT | MDEDVGLEATNYSRGDESRSEEQEKNVVRWRIVQQSTGPNPKPRHGHRAVVLKELIVIFGGGNEGMIDELHAYNTQKREWTAPQCCGDVPTPAAAFGAISLGNKIYRFGGMTEYGKYTNDLYELQSTRWEWRRLNPRVHSNGHLPCPRIGHSFVVSQKSQKAYVFGGLSNDLNDPKRNVPHYLDDLYVINLSGPQHLIWEKLNATGPGPISRESHTAVIYEKDSISRMVVYGGMNGVRLGDLWYLNLNTLHWTEIKFDDPRTGIPPMPRSLHSSVLIGDKMFVYGGWVPLLEHASTEQQTEKEWKCTSSLGCWNITEDRW... | chromatin remodeling dauer exit defense response to other organism determination of adult lifespan negative regulation of protein localization to nucleus negative regulation of transcription by RNA polymerase II negative regulation of transcription by transcription factor localization positive regulation of transcripti... |
cell differentiation dephosphorylation intracellular signal transduction mitotic cell cycle muscle organ development nematode larval development oogenesis positive regulation of epidermal growth factor receptor signaling pathway positive regulation of Ras protein signal transduction positive regulation of vulval develo... | cytoplasm; cytoplasmic vesicle | non-membrane spanning protein tyrosine phosphatase activity phosphotyrosine residue binding | Caenorhabditis elegans | Cytoplasm Differentiation Hydrolase Oogenesis Protein phosphatase Reference proteome Repeat SH2 domain | MPRLALRQYN | MPRLALRQYNFYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLSIFEDERTTPNQFGSITELAEFYMEFPEKLREKNGLFLELKKPVYVPYHLEACAEEQRRTQLYRWWHGNLPASSANKLLQTEKNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGRFNIDGDRTKFQSAWLLIDSYSKNPIVEKGEASRVLYLEEPLFNTFIEADLFVDRFEIIRRPINPRESMEKTGISEEFDRLSQEALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGS... | cell differentiation dephosphorylation intracellular signal transduction mitotic cell cycle muscle organ development nematode larval development oogenesis positive regulation of epidermal growth factor receptor signaling pathway positive regulation of Ras protein signal transduction positive regulation of vulval develo... |
axonogenesis body morphogenesis gonad morphogenesis head morphogenesis locomotion nematode larval development neuron fate specification pharynx development positive regulation of transcription by RNA polymerase II | nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding | Caenorhabditis elegans | DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MNICMRNGYE | MNICMRNGYEQFSLTSPGTSDLEIGGSFWKDEPDTKYLCLDSPVEQRQHQPPMAVCAGCRLEISDRYFLRVNPNLEFHAQCLKCVQCSRPLDENQTAFVKNGQTYCRDDYRRLFTTRCSRCHGDFDKTDLVMRAGPQNVFHLNCFACVACEKRLQTGEEFQIKNNSLYCRSDCRGLDNPDTSASVPDYSKLNNNNNNDNNNSSSNFDEDEWDEERSTLTSLDNNTSSPLGSPKSDGVRTPLFGHHNSGSGGSTSSCGKKKKDKQATRVRTVLNENQLKILRDCYSINSRPDATLKERLVEMTGLSARVIRVWFQNKRCKD... | axonogenesis body morphogenesis gonad morphogenesis head morphogenesis locomotion nematode larval development neuron fate specification pharynx development positive regulation of transcription by RNA polymerase II nucleus cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA... |
autophagy regulation of DNA-templated transcription | cytoplasm; nucleus | protein self-association protein-macromolecule adaptor activity transcription coregulator activity | Caenorhabditis elegans | Coiled coil Cytoplasm Nucleus Reference proteome | MTPLSALTSN | MTPLSALTSNPAPSPPPKFALGKCPATAIHVVSVLRPNRQRFCYEKTDAGDLIPHKCLICQPILTEKHISPYYAVYSDLLEDFVLFGYNTMTGKMEQFIYAFKTDCFVEVNRPEIKYNPAFLVKGNVVVALNGPEGELVVIERDCRGLLSKESTSYGQFRTLPTAALRTLTLQDLERDRWDRAANSDEVKISSGNESFDRLYAEYQKNLPRFQVRQCLHLNKEFLCVYSKTSGDYTRLEYIDETGDFQKISCTLCTCEVTESNLIPLYVERNASELVIHVHNTENNQIEQYIYDVRTFGFVQVKRNLVYDPKKITSGLNL... | autophagy regulation of DNA-templated transcription cytoplasm; nucleus protein self-association protein-macromolecule adaptor activity transcription coregulator activity Caenorhabditis elegansCoiled coil Cytoplasm Nucleus Reference proteome MTPLSALTSN MTPLSALTSNPAPSPPPKFALGKCPATAIHVVSVLRPNRQRFCYEKTDAGDLIPHKCLICQPILTEKH... |
DNA damage checkpoint signaling DNA repair intrinsic apoptotic signaling pathway in response to DNA damage nucleotide-excision repair telomere maintenance telomere maintenance via telomerase | checkpoint clamp complex; nucleus | 3'-5' exonuclease activity damaged DNA binding double-stranded DNA 3'-5' DNA exonuclease activity | Caenorhabditis elegans | DNA damage DNA repair Exonuclease Hydrolase Nuclease Nucleus Reference proteome | MMELETGQCT | MMELETGQCTIMELKKENVKELAQVFKTVAFKDTGTWHASEAGMKITVDDGSYQLASVFINPAFFSSFKVREEIVSMKISIKSISEFLSISENSSSSVKVSYPGMFQPVKMLVEDADGWVARGNFTTTLADQELDFEFDDAGVLATYLLKTQVLKEIIKDFDDTSRTVRIQFTKNSLCFTTFGDVGETTVSIPSRSLQMESVKCLEEVEFSYLLSLIQRMTTAFILATKLILRVDERGVLSCQFSIDHGEGNASYIEFLTVPADEEE | DNA damage checkpoint signaling DNA repair intrinsic apoptotic signaling pathway in response to DNA damage nucleotide-excision repair telomere maintenance telomere maintenance via telomerase checkpoint clamp complex; nucleus 3'-5' exonuclease activity damaged DNA binding double-stranded DNA 3'-5' DNA exonuclease activi... |
axon guidance neuron development positive regulation of transcription by RNA polymerase II regulation of axon extension regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Transcription Transcription regulation | MMMEYGGYFS | MMMEYGGYFSSSAVAQQSGDVPTTAPSAVTNSFFYTPQSHNIYHQYATPYLQSGRALTTAHNTSSSSAGNSTSSSSSSSNYRNTTHDSLQAFFNTGLQYQLYQKSQLIGSDTIQRTSSNVLNGLPRSSLVGALCSTGGAPLNPAERRKQRRIRTTFTSGQLKELERSFCETHYPDIYTREEIAMRIDLTEARVQVWFQNRRAKYRKQEKIRRVKDEEEDPLKKEPGQISLEEIIDQI | axon guidance neuron development positive regulation of transcription by RNA polymerase II regulation of axon extension regulation of transcription by RNA polymerase II nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription fa... |
G protein-coupled receptor signaling pathway gamma-aminobutyric acid signaling pathway negative regulation of synaptic transmission, cholinergic regulation of locomotion response to xenobiotic stimulus | G protein-coupled GABA receptor complex; G protein-coupled receptor heterodimeric complex | G protein-coupled GABA receptor activity | Caenorhabditis elegans | Cell membrane G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MSRWLSLLLF | MSRWLSLLLFAVQAVGGYEAGEELSCKRRHGGIPLPLGVFTVQKEGFPDALPAIRTALSHVHSRSCILQGYRLEMIVKDTHCKTSQGMKALFDLIASRPRPVAILGGQCTEVNEPIAMALKYWQIVQLSYAETHAKFASSDSHELFTTFFRVVPGSRNTNMAKCKFVNHFGWKRVGTVKQNDQPRYALPHEALTTRLEHGFGVKIVHTAGVNWEQIETVGGELDELKERDVRIILVDVDEEMAATVLCAGYHRGMYGDNYVWILPGYHSDKWLNQTHDNCTVEEMREAAKNHFSVEFALTRRDVDTKIVGNTRAGDVWNE... | G protein-coupled receptor signaling pathway gamma-aminobutyric acid signaling pathway negative regulation of synaptic transmission, cholinergic regulation of locomotion response to xenobiotic stimulus G protein-coupled GABA receptor complex; G protein-coupled receptor heterodimeric complex G protein-coupled GABA recep... |
lipid transport involved in lipid storage neuropeptide signaling pathway positive regulation of defecation positive regulation of intestinal lipid absorption positive regulation of triglyceride transport regulation of defecation | cilium; plasma membrane | neuropeptide receptor activity | Caenorhabditis elegans | Cell membrane Cell projection Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSTDIIANV | MNSTDIIANVTKPFVENLTLGETAFYISCGIVGTVFNALVLWIALTYINTEDKPRQIIVINMTVADLLMCIVYMKTRPWLSHFNLWLCHPYYVIIWTCQMCSCLNLVWLNVDKLIYIQFPLHYYQIVNRKRLLWITAATWGGLYAMNIALVTFLKITRGSCLGVSLNPYVYLLSPIFYVVMILTSFSLSALIYCIAHNLTHMEERQRSKLFRRLFFLFSSTLWTFFTCLPYRLLYLFSIFCGETCQINNYYKTATNLFFRLLIVGIMINPVITIWTQRIYRLRLMRMFGRLRENSSTEVLMVSNRRASERPPEHTPLRCD... | lipid transport involved in lipid storage neuropeptide signaling pathway positive regulation of defecation positive regulation of intestinal lipid absorption positive regulation of triglyceride transport regulation of defecation cilium; plasma membrane neuropeptide receptor activity Caenorhabditis elegansCell membrane ... |
astral microtubule organization cell division embryo development ending in birth or egg hatching meiotic cell cycle microtubule-based process mitotic spindle elongation mitotic spindle organization negative regulation of microtubule depolymerization pronuclear migration regulation of microtubule polymerization | axon; centrosome; cytoplasm; kinetochore; meiotic spindle; mitotic spindle astral microtubule; mitotic spindle microtubule; perikaryon; spindle; spindle pole | protein domain specific binding | Caenorhabditis elegans | Cell cycle Cell division Cell projection Centromere Chromosome Coiled coil Cytoplasm Cytoskeleton Kinetochore Meiosis Microtubule Mitosis Reference proteome | MSLNTTFTKE | MSLNTTFTKEDGTEVVIPFNGSQNGHPENEEPEVEEAAEPSSSVETLCGATRGDIIVMKHTTKALTELIERLLHSDEFEVRRCSNGQIISQGRCNGTTPGNGIGGGGASSEELEKALKDRDAARAEADKLHANYATLFASFNTVREAANDIRGEYEDARDKLKLAAAEVDEWQAKFLAVKDNANSELERASVEYDDLLRSHDENTKGLRLRVKRQEIELSSKNDEIKVLTNRVSELSQICDQLLNDVDVSDGMSVISTDA | astral microtubule organization cell division embryo development ending in birth or egg hatching meiotic cell cycle microtubule-based process mitotic spindle elongation mitotic spindle organization negative regulation of microtubule depolymerization pronuclear migration regulation of microtubule polymerization axon; ce... |
anatomical structure morphogenesis basement membrane disassembly cell fate specification determination of adult lifespan innate immune response negative regulation of stress response to copper ion negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regul... | nucleus; RNA polymerase II transcription regulator complex | chromatin binding DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription fac... | Caenorhabditis elegans | Alternative splicing Coiled coil DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Stress response Transcription Transcription regulation | MFEQPSSTTN | MFEQPSSTTNTTTSSGSGSDSNHYFELGPRNPINQAHPTSVIVPPRQHHHQIHQQQTDNSPLTPCTPYYPSNAYGLPLFFGTDFLQFQPSDIPSPLTPNISSPLTPHPFGPIPAIPTNQIYNRTFTDFYSTAASSPMVQYSTVKKSSAGRKPKEEDNMEDDDDDKRLKRRQRNKEAAARCRQRRIDLMKELQDQVNDFKNSNDKKMAECNNIRNKLNSLKNYLETHDCKLSREERTHEINRLIIPPSTVPPSQPYLQHSLRVHPPRADSVPYSIRSGHSSSSSEQHSPVEDYKPSIDQLLLPPISCIQNIKDRNINSMPP... | anatomical structure morphogenesis basement membrane disassembly cell fate specification determination of adult lifespan innate immune response negative regulation of stress response to copper ion negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regul... |
endoplasmic reticulum unfolded protein response lipoprotein metabolic process lipoprotein transport plasma lipoprotein particle assembly | basolateral plasma membrane; endoplasmic reticulum; Golgi apparatus | lipid binding phospholipid transporter activity | Caenorhabditis elegans | Endoplasmic reticulum Lipid transport Lipid-binding Reference proteome Signal Transport | MFSSRIWLLL | MFSSRIWLLLAVTVGVCLAVPDLDEIKKNLRKHGPDYYKNQPKMNENTVRLLKVDYWFRTESMIYDDIDNKEKDPSTVIAGNFSFETLHHDVEGGMLGRFTLTQCNTDNCGNPSPIYIAFRQGGNNAEHILKASDESDATWNFLYAIVNTIYTPAEYGEGDEQTVDTIYGRCFVNFGRPEDKRFRRIIEKCDLGYGTNFTKFEGIESVQYDQDVWYTQNTKVDADIIMVDAIEMLAFKSPLHEKYGFTLESRTHVEITNRTRVFVTSYCNDTVPSAKCAEQAFGAVRVGGKLYEHVKIAQEQSNKLTKLIGTYRRHLQDM... | endoplasmic reticulum unfolded protein response lipoprotein metabolic process lipoprotein transport plasma lipoprotein particle assembly basolateral plasma membrane; endoplasmic reticulum; Golgi apparatus lipid binding phospholipid transporter activity Caenorhabditis elegansEndoplasmic reticulum Lipid transport Lipid-b... |
anterograde neuronal dense core vesicle transport axonogenesis cell cycle cell division chemical synaptic transmission establishment or maintenance of microtubule cytoskeleton polarity negative regulation of dense core granule transport neuron apoptotic process phosphorylation positive regulation of dense core granule ... | axon; axon cytoplasm; cytoplasm; dendrite; nucleus; protein kinase 5 complex; synapse | ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein kinase activity protein serine kinase activity | Caenorhabditis elegans | ATP-binding Cell cycle Cell division Cell projection Cytoplasm Kinase Magnesium Metal-binding Neurogenesis Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MLNYDKMEKI | MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFADTSDV | anterograde neuronal dense core vesicle transport axonogenesis cell cycle cell division chemical synaptic transmission establishment or maintenance of microtubule cytoskeleton polarity negative regulation of dense core granule transport neuron apoptotic process phosphorylation positive regulation of dense core granule ... |
chloride transmembrane transport defecation lipid transport involved in lipid storage positive regulation of intestinal lipid absorption positive regulation of muscle contraction potassium ion transport sodium ion transport | neuromuscular junction; neuron projection; plasma membrane; postsynapse; synapse | excitatory extracellular ligand-gated monoatomic ion channel activity GABA receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Caenorhabditis elegans | Alternative splicing Cell membrane Disulfide bond Ion channel Ion transport Membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MSASILILAT | MSASILILATCHQVLADFNSYVVPQPHAQRDHRQDISQHYDYLMEENDEPLGRGAAPSKYRSSHGQAQHRPEMTESENFAQPNTESVFSSGGVDSYGETRDFLQFLRRIQYDHRQVPENEKGEATYVEVSVVVSNIRAVSEVTMDYALELFYRESWRDPRLQYDRKLFKNKTELALHESYTNFLWFPDTFVPNAIASKNPQRNSISHRSLLRLDETGKLLYSRRISLVCECTMDLTLFPFDKQLCKLGIESYGYTADHVVYKWSKGARTALELKKIRLPDFTIQEAYVTSQMESYATGNYSRLYVCFVFSRSSGFCFLQL... | chloride transmembrane transport defecation lipid transport involved in lipid storage positive regulation of intestinal lipid absorption positive regulation of muscle contraction potassium ion transport sodium ion transport neuromuscular junction; neuron projection; plasma membrane; postsynapse; synapse excitatory extr... |
embryo development ending in birth or egg hatching larval feeding behavior muscle cell development nematode larval development nematode pharyngeal pumping phosphorylation | cell-cell junction; plasma membrane | ATP binding metal ion binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity | Caenorhabditis elegans | Alternative splicing ATP-binding Kinase Magnesium Manganese Metal-binding Nucleotide-binding Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MSNGNSYNHH | MSNGNSYNHHHQFPMSIPISCSSHSIQSQSRMNTLNANRDLLSPGNDVIVTRTVSPSFYSHGMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGML... | embryo development ending in birth or egg hatching larval feeding behavior muscle cell development nematode larval development nematode pharyngeal pumping phosphorylation cell-cell junction; plasma membrane ATP binding metal ion binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase acti... |
negative regulation of gene expression neuron fate determination regulation of DNA-templated transcription regulation of male mating behavior regulation of nematode male tail tip morphogenesis | nucleus | metal ion binding sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing DNA-binding Metal-binding Nucleus Reference proteome Zinc | MPKEQYMCQL | MPKEQYMCQLCANHGIFNQPKKGHKQKCPYRTCPCSLCALNTKRRALDQIERQLKHTNEPMTGQTATSMASPTPECPLSPTTPKMTPHTPTSGKDTFRNSISSSNMAFTVQLPATITKKELKLLRRDDTPLQNSLERPFPRSIDEAIETIKKEKMSSIFHSAEMLAVGESATSLI | negative regulation of gene expression neuron fate determination regulation of DNA-templated transcription regulation of male mating behavior regulation of nematode male tail tip morphogenesis nucleus metal ion binding sequence-specific DNA binding Caenorhabditis elegansAlternative splicing DNA-binding Metal-binding Nu... |
positive regulation of vitellogenesis regulation of oocyte development regulation of protein processing | cytoplasm; extracellular space; vesicle; yolk granule | cysteine-type endopeptidase inhibitor activity | Caenorhabditis elegans | Cytoplasm Disulfide bond Protease inhibitor Reference proteome Secreted Signal Thiol protease inhibitor | MKAILVFALI | MKAILVFALIAISIISVNAGMMTGGSVEQDASQKEYSDKAWKAVKGINDQASNNGPYYYAPIKVTKASTQVVAGISTKLEVLVGESNCKKGELQAHEITSSNCQIKDGGSRALYQVTIWEKPWENFEQFTVEKIRDVTADEQF | positive regulation of vitellogenesis regulation of oocyte development regulation of protein processing cytoplasm; extracellular space; vesicle; yolk granule cysteine-type endopeptidase inhibitor activity Caenorhabditis elegansCytoplasm Disulfide bond Protease inhibitor Reference proteome Secreted Signal Thiol protease... |
asymmetric neuroblast division establishment or maintenance of cell polarity maintenance of dauer negative regulation of apoptotic process involved in development positive regulation of peptidyl-threonine phosphorylation protein localization to synapse stress-activated MAPK cascade synapse organization | axon; cell body; cell cortex; dendrite; neuron projection; nucleus; perikaryon; synapse | ATP binding MAP kinase kinase activity protein kinase binding protein serine/threonine kinase activator activity | Caenorhabditis elegans | ATP-binding Cell projection Cytoplasm Neurogenesis Nucleotide-binding Nucleus Reference proteome Synapse | MADTTILDTT | MADTTILDTTCSSTLAANVEFSHATDSAIGISLKNATITEAEGVPNLKETGYDCVRYMGTCNGGQIYLGRERKKLKDYVAIKKFAIDDVDDYAAIAKESSNLRLMHHPNIIELCECFVYERSIYQITPAMNLGSLFDIVFEYMKWGINEKSAAAITRQLLDALSYLHQRRYIHRDLKPKHILIDSSGNVKLSGFRFMIELNHHLDCVFEFDAHLQNQLYYLAPEVLAQNIHGYTSKSDIYMLGISICEAINGVMPFGELEPLEMLHRKLNGQVPRPVDMISLKDDQKMGLDISHRPQEHLTRRFSKEMHEFIANCLDYDP... | asymmetric neuroblast division establishment or maintenance of cell polarity maintenance of dauer negative regulation of apoptotic process involved in development positive regulation of peptidyl-threonine phosphorylation protein localization to synapse stress-activated MAPK cascade synapse organization axon; cell body;... |
cellular response to lipopolysaccharide cytokine-mediated signaling pathway innate immune response intracellular signal transduction phosphorylation regulation of response to stimulus Toll signaling pathway | cytoplasm; nucleus; plasma membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | Alternative splicing ATP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MDDSLGVSEV | MDDSLGVSEVVMIPFMKREVLQQICAILDTDNTWETIAPYMPGIELRDVEGCKRYSSYNQSPSELLLRIWSSKGYSTTHLYQLFAKTKLIRLMRMMRSQVHEKYHYLENKVTNSTSRVSKQMVQPPGSQSASRLKKTEIKESSPSPAAAAASQLSRSNTDDTLRVAIEGTLPVTYCELLEATNGFAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNGSLEDRLLCRKGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIK... | cellular response to lipopolysaccharide cytokine-mediated signaling pathway innate immune response intracellular signal transduction phosphorylation regulation of response to stimulus Toll signaling pathway cytoplasm; nucleus; plasma membrane ATP binding protein serine kinase activity protein serine/threonine kinase ac... |
canonical Wnt signaling pathway motor neuron migration neuroblast migration neuron migration non-canonical Wnt signaling pathway positive regulation of motor neuron migration sensory neuron migration | plasma membrane | G protein-coupled receptor activity Wnt receptor activity Wnt-protein binding | Caenorhabditis elegans | Cell membrane Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Membrane Neurogenesis Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix Wnt signaling pathway | MLLRISVLFL | MLLRISVLFLLLGSCGALFGKRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQENYDKPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQHKGHHHKNQNQNQNQNHNYSPDGPEVGISKIDNEVIAGPSECQCTCNQPFQFVASEKSKVGNVTNCAYSCHSPALAESHSLVSNWMAFWSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIACDSMRIKGADDNSGSLCFVVFLLTY... | canonical Wnt signaling pathway motor neuron migration neuroblast migration neuron migration non-canonical Wnt signaling pathway positive regulation of motor neuron migration sensory neuron migration plasma membrane G protein-coupled receptor activity Wnt receptor activity Wnt-protein binding Caenorhabditis elegansCell... |
cell differentiation cell fate specification hormone-mediated signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II | nucleus | nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Activator Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MQDGSSGAAS | MQDGSSGAASLGNSSPDATDCVVCGDKSSGKHYGQFSCEGCKSFFKRSIRRSLSYTCRATKNCAIDVQHRNQCQYCRLTKCIRMGMRKEGRRSNETQTAVSAVQRGRLPVTMPSLFPPNMFLRSPFPFMSVPFNPLMTAQFTKPSIKESIFEFAAQTIFATVNWARTSMSNLVKGDQLILLRHSWTPIFIFALAQSNFALNLSTHLTAVTATAASTENGSSSLGSKSEDEEKSEEKPERVFDEPQFQGFQAKIDKIRDFHLDVVESSSLRAVLLFSCDEEALEEKGKIEEIVEKLKSAVDEYCKMNKRSERYHQICECLQ... | cell differentiation cell fate specification hormone-mediated signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II nucleus nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Cae... |
defecation lipid transport involved in lipid storage positive regulation of intestinal lipid absorption positive regulation of striated muscle contraction | membrane; neuron projection; synapse | extracellular ligand-gated monoatomic ion channel activity neurotransmitter receptor activity transmembrane signaling receptor activity | Caenorhabditis elegans | Alternative splicing Disulfide bond Ion channel Ion transport Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix Transport | MTRLSILQHL | MTRLSILQHLLTFLILSKINATSTTESYFDSSEEAPNVLLNHLNNESEGEELTQINDTQPAFVPGSSKRLTEYLLSRHNLNAPPDGLLYVEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWDPALFGGITKTWIPLDKIWVPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNGTIVASHPAVHTVSCEINIRHFPLDDQRCAIEIASWAYGQEKIRLHAHTDHSLEHYKRNEEWHLLNLNVSEEKYEHEGVEVSEVKFEISLKRRPLFYMVTLTFPSYIMCAISVVGLFARFSTTGEREERFTLGVTAILTMAV... | defecation lipid transport involved in lipid storage positive regulation of intestinal lipid absorption positive regulation of striated muscle contraction membrane; neuron projection; synapse extracellular ligand-gated monoatomic ion channel activity neurotransmitter receptor activity transmembrane signaling receptor a... |
female sex differentiation negative regulation of centrosome duplication negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of gene expression negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage nervous system development positive... | cytoplasm; nucleus; SCF ubiquitin ligase complex | cullin family protein binding | Caenorhabditis elegans | Developmental protein Neurogenesis Reference proteome Ubl conjugation pathway | MADQKKVSEA | MADQKKVSEAAKEREIKISSSDNEIFLVPRNVIRLSNTINTLLMDLGLDDEEGTNAEPIPVQNVTASILKKVISWCNHHHSDPISTEDSDNREKRTDDIGSWDVEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKSPEEIRRTFNIKNDFTPEEEEQIRKENAWCED | female sex differentiation negative regulation of centrosome duplication negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of gene expression negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage nervous system development positive... |
determination of adult lifespan positive regulation of gene expression positive regulation of RNA splicing regulation of cell cycle regulation of cell population proliferation regulation of transcription by RNA polymerase II response to starvation response to toxic substance | nucleus; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MEEDQEEPPS | MEEDQEEPPSSSTSSESPEVVLKAPKAPTRRRKNSKKDRRQDMEVDDGEKESTAQYCKGFYDALRVMQTTNKYEFTGGAVSSPVLPVLQTAAFSPITPASASDMHTIVMSLLGNTPITSGPSIAPLSSPTLLPLVTSGDLDDLSMKILASSAIPGPPIISSSNSPDSSTTAVTTSQITAFQPLLNNFVSSTTASTSRPDKLNLTPPQQSAEIYAFNGVNSDDSDGGLDSRSASRCGMALDDQEKKKLERKRARNRQAATKCRQKKMDRIKELEEQVLHEKHRGQRLDAELLELNRALEHFRRTVEHHSGNGCPNNSIRV | determination of adult lifespan positive regulation of gene expression positive regulation of RNA splicing regulation of cell cycle regulation of cell population proliferation regulation of transcription by RNA polymerase II response to starvation response to toxic substance nucleus; transcription regulator complex DNA... |
inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process involved in development positive regulation of apoptotic process involved in development positive regulation of egg-laying behavior positive regulation of em... | cytoplasm | caspase binding cysteine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process zymogen binding | Caenorhabditis elegans | Cytoplasm Reference proteome | MFFGKLGGFA | MFFGKLGGFAFFLQRAVRCDGFIDNFFDRIPKFFQFMKSKFPSHQTSSSQADLLVSFSTSPGFLSFKDETKDTWYIQELYRVIIENAKDTHLADLLTETNRRVVEKYEADKVVFVCKQAPEFWSRFTKQLFFMSRNDVF | inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process involved in development positive regulation of apoptotic process involved in development positive regulation of egg-laying behavior positive regulation of em... |
cell-cell adhesion chemical synaptic transmission embryo development ending in birth or egg hatching establishment or maintenance of epithelial cell apical/basal polarity receptor clustering receptor localization to synapse zonula adherens assembly | adherens junction; apical junction complex; apical plasma membrane; basolateral plasma membrane; cytoplasm; lateral plasma membrane; neuromuscular junction; neuron projection; postsynaptic density membrane | guanylate kinase activity | Caenorhabditis elegans | Alternative splicing Cell junction Cell membrane Cytoplasm Membrane Reference proteome Repeat SH3 domain | MSHESSEKAH | MSHESSEKAHKAIENVEDYCQTLTRHGNEELRTNLERVITTFKSNLMHSLLDIHDLYEQTLLSERKSDAEKNMEVRRVIERLEGGPHSYNSRPAATTSTSNYNLSSTTPLISDLRDRGGFSYLNGGGLGNGLGNGLGNGLLSSPYNSSSTHYLHERQRQTSHDGTWRETTTRTVDTPSGLERRVVEHTGVIDDHGRKWELENIVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLPIGGNFGGSTSYLRSGVTPSVSAGNL... | cell-cell adhesion chemical synaptic transmission embryo development ending in birth or egg hatching establishment or maintenance of epithelial cell apical/basal polarity receptor clustering receptor localization to synapse zonula adherens assembly adherens junction; apical junction complex; apical plasma membrane; bas... |
anatomical structure development apoptotic process cell fate specification embryo development ending in birth or egg hatching nematode larval development nematode male tail tip morphogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II uterus development vul... | chromatin; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding | Caenorhabditis elegans | Chromosome Developmental protein DNA-binding Nucleus Paired box Reference proteome Transcription Transcription regulation | MEPIWRNYPY | MEPIWRNYPYPTYPGHHNFQFDPLLSDGSHTGVNQLGGVFVNGRPLADTVRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNKSFMAQLAAPTSVTSSAARPSSATSHHQRSPPRGVQQHMQQSTSVQQLQQLQLTSAATVNSLMTPPAFAMPGTAYSINGLLGTLPQPSLLDDKFTNLSTQSADMSLVYSTGLVGEHDWTMRTPMVILPQNYCGQL | anatomical structure development apoptotic process cell fate specification embryo development ending in birth or egg hatching nematode larval development nematode male tail tip morphogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II uterus development vul... |
aminophospholipid transport apoptotic process involved in development recognition of apoptotic cell | cell surface; extracellular vesicle | phosphatidylserine binding protein homodimerization activity protein-macromolecule adaptor activity scavenger receptor binding | Caenorhabditis elegans | 3D-structure Apoptosis Reference proteome Secreted Signal | MSRFLIYFLP | MSRFLIYFLPFFIYSGNVLSKTSCLMATGVLKCPTDPEAVKKVHIDLWDEDSLPLESDDLMGRTWSDRNGNFQVTGCASDFGPINTPDPYLYIQHNCPHRDSNATNPIQIDVIPLFLPSIVRLGNVYLDRYLEDY | aminophospholipid transport apoptotic process involved in development recognition of apoptotic cell cell surface; extracellular vesicle phosphatidylserine binding protein homodimerization activity protein-macromolecule adaptor activity scavenger receptor binding Caenorhabditis elegans3D-structure Apoptosis Reference pr... |
associative learning homophilic cell adhesion via plasma membrane adhesion molecules olfactory learning positive regulation of synapse assembly positive regulation of synaptic transmission positive regulation of synaptic vesicle transport regulation of synaptic transmission, glutamatergic synaptic transmission, GABAerg... | axon; cell surface; extracellular space; Golgi apparatus; Golgi membrane; intracellular membrane-bounded organelle; neuromuscular junction; neuronal cell body; neuronal cell body membrane; perikaryon; postsynaptic membrane; synaptic cleft | amyloid-beta binding calcium ion binding kinesin binding X11-like protein binding | Caenorhabditis elegans | Alternative splicing Calcium Cell adhesion Cell projection Glycoprotein Golgi apparatus Membrane Reference proteome Repeat Secreted Signal Synapse Transmembrane Transmembrane helix | MRTAYFIFVG | MRTAYFIFVGALLGVSYAKHHHAARAPIINLQGAEELVAVVREDENIISTVPDFAILSETGPVCNYLLTSQNNEPVPFDIQVVDKYTGAAVLRVKDAATLDCKKPEYNLQVQAVKCDNDNVKSEGVSLKIRVKDTNNHAPEIENPWYTFHVEEGKVVEEVGVLKASDKDCGHPNGEICEYEITNGLKELPFAINNHGVLRTTQPLNFTQSKSYILTVVAIDCAMRKSKSSLVTVHVDEKCVQGITAMNERVNYAPGVGSKLLLPDVSLEFCEKETICEPKSVQSVIELRAGHVTQGCARDTVYDNQTIQSCGLSTATVKL... | associative learning homophilic cell adhesion via plasma membrane adhesion molecules olfactory learning positive regulation of synapse assembly positive regulation of synaptic transmission positive regulation of synaptic vesicle transport regulation of synaptic transmission, glutamatergic synaptic transmission, GABAerg... |
intracellular zinc ion homeostasis positive regulation of transcription by RNA polymerase II | cytoplasm; nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Cytoplasm DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MQKVMNDPED | MQKVMNDPEDLGNCKICLQRADGIHFAVSSCRACAAFFRRTVILKLNYTCKEKGNCTVEKSLRNLCRSCRYTRCINEGMKIELVQLQRDSIGRKKSGASISIDPLFTPNVASSLSAIFKNEKEDVLSTSCTILSQMTSGYAMFLNIRRSTNTLVQSSVITPTFKMPKIELHASRFDSAKQVCKAEAHLVTDIVNSYFSPFNSLKFEDKVALFKNFFCYFSHTDRAYQSFKQFESDNLNDKILMPDGGFIKRTELGRFYENAEGVHTSAEDAAKIFQPALNYILDVIVDYMRRIHIIETEYLALLGFCLWDDAVPGLSKEA... | intracellular zinc ion homeostasis positive regulation of transcription by RNA polymerase II cytoplasm; nucleus cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Caenorhabditis elegansCytop... |
anatomical structure development epidermal cell fate specification gonad morphogenesis hemidesmosome assembly regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Developmental protein DNA-binding Homeobox Nucleus Paired box Reference proteome Transcription Transcription regulation | MTTDSITFNH | MTTDSITFNHILGQGRVNQLGGVFINGRPLPIHVRHAIISMAKKGIKPCHISRQLKVSHGAVSKILNRYAETGSISPGQIGGSPRARLTVQAVEKEILIACDENPQMSAAELRDWLIHKDICTKGNAPTVPAIKRLIGNKGVGVPKKMERKRLSYSIDSILGISIDECSKSSSDDEEGSSPSNDASSRRNRTSFTAEQLDVLENAFRADTYPHANARESISKETGLSEEKIMTWFSNRRARCRKNMPMYQQYNVQGFGSSPPSYPTLLPSPMMFLPSYSTSPQLNPLFFQHILQSSPPSSQSSPPSSS | anatomical structure development epidermal cell fate specification gonad morphogenesis hemidesmosome assembly regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding Caenorhabditi... |
endocytosis nematode larval development phosphatidylinositol dephosphorylation phosphatidylinositol metabolic process regulation of cell migration regulation of Wnt signaling pathway synapse assembly | apical plasma membrane; cytoplasm; cytosol; phosphatidylinositol phosphate phosphatase complex; plasma membrane | metal ion binding phosphatase binding phosphatidylinositol-3,5-bisphosphate phosphatase activity phosphatidylinositol-3-phosphate phosphatase activity | Caenorhabditis elegans | Alternative splicing Cell membrane Cytoplasm Endocytosis Hydrolase Lipid metabolism Membrane Metal-binding Reference proteome Zinc Zinc-finger | MRFEDIGISK | MRFEDIGISKVDKVCLVDRLGCQENLVGTVHVTTTHIIFRAENGSKELWLATGLISSVEKGTLTAAGCMLVIRCKHFQVITLLISRDKSCQDLYETLQRAAKPVSVNVTELLAFENREPVEDVRGWRRLDWNSEMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSARCVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKTLEASGWLKHVRSVVECSLF... | endocytosis nematode larval development phosphatidylinositol dephosphorylation phosphatidylinositol metabolic process regulation of cell migration regulation of Wnt signaling pathway synapse assembly apical plasma membrane; cytoplasm; cytosol; phosphatidylinositol phosphate phosphatase complex; plasma membrane metal io... |
meiotic cell cycle nematode larval development nematode male tail tip morphogenesis positive regulation of vulval development Ras protein signal transduction vulval development | cytoplasm | ATP binding metal ion binding protein kinase activity protein tyrosine kinase activity | Caenorhabditis elegans | Alternative splicing Meiosis Metal-binding Reference proteome Zinc Zinc-finger | MSDEKKKKRG | MSDEKKKKRGFFRYSVLTTSSFSSWRRSSTSGSISQSSRTTSKTTTSSSVTSSNPINAPPPTATSSSSVLPSTSSEPPPPASAPPRISIYHKMVPSKSKFRQCDVCEHIFIFDFVRKQHLDDVYACNVCGIRVHKGCLDRVKNDCKITTQYMGGILENAVIQSNKKQWEKPTTASISKSLTTSPTCSTSTTMSPAGVEKNVHKTRKLISMTTSTLDDVTTFNSEINEEMDEETVLMTWEDVTIKLTDVDVMTKIGDGRFGSVYFGGYHGNAAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGYVSDPVTN... | meiotic cell cycle nematode larval development nematode male tail tip morphogenesis positive regulation of vulval development Ras protein signal transduction vulval development cytoplasm ATP binding metal ion binding protein kinase activity protein tyrosine kinase activity Caenorhabditis elegansAlternative splicing Mei... |
phosphorylation regulation of RNA splicing | cytoplasm; nucleus | ATP binding protein serine/threonine kinase activity protein tyrosine kinase activity | Caenorhabditis elegans | Alternative splicing ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MPILHQKIAS | MPILHQKIASTGGQPSTNSLALRRLPLVVIPRKRKYKNYVSRRRNTQLLASLRRCVSDPNVYKSYNHWKALLRPMTPIKSGAPTPKTVTPMPVPQIPPHQKMTPNPTPTQNPVQLPLPHAVSEKPGDKKSTGPTPSPVPSKAPISAAKLPGTVTKVAPLLSAAQPPPKTLAPAPGASETNSGSGPVSKQVSGKLTELKSKNGTVTEKTEKAVLRIPSSASTRAKAASAVAPEANPAPVPTATKPSPFAPAIAPLRDGAPAQPPAPIQASAPLRPPVAKQNSLQKPPEPKRSVGAPPKALPSELVNKIDGIEFLPQSSNQN... | phosphorylation regulation of RNA splicing cytoplasm; nucleus ATP binding protein serine/threonine kinase activity protein tyrosine kinase activity Caenorhabditis elegansAlternative splicing ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-p... |
negative regulation of apoptotic process negative regulation of insulin secretion negative regulation of neurotransmitter secretion negative regulation of transcription by RNA polymerase II neuroblast fate specification regulation of backward locomotion regulation of forward locomotion regulation of neuron differentiat... | axon; nucleus; perikaryon | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription corepressor activity transcription corepressor binding | Caenorhabditis elegans | Cell projection Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MSTEHVSNVY | MSTEHVSNVYSVESLLSNVEKSSVSPTESIEDRNEFMITEDVMSSWQRMAATISLQQKLLMMQQTMPRPPPVNILGNFPFGFLNAPMFWQQYLRSMAMGIIPQNPESPSASVWNRTPTPPVEIKPFHCQKCTKLFSTIAALEQHQQVHVSDKQFECKQCGKTFKRSSTLSTHLLIHSDTRPYPCEYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCGKAFSQSSNLITHTRKHTGFKPFACDVCGRTFQRKVDRRRHRESHHPGHPEECVSASQISSDLSPKGYMTPPTSNGYLDSSDEFLNVFRLPAELLAIKAEMGEEM... | negative regulation of apoptotic process negative regulation of insulin secretion negative regulation of neurotransmitter secretion negative regulation of transcription by RNA polymerase II neuroblast fate specification regulation of backward locomotion regulation of forward locomotion regulation of neuron differentiat... |
chromatin organization chromosome attachment to the nuclear envelope dauer larval development determination of adult lifespan germ cell development gonad development negative regulation of gene expression negative regulation of Ras protein signal transduction negative regulation of vulval development nematode larval de... | chromosome; nuclear inner membrane; nuclear periphery; nucleus | chromatin binding H3K27me3 modified histone binding methylated histone binding | Caenorhabditis elegans | Alternative splicing Chromatin regulator Chromosome Nucleus Reference proteome Transcription Transcription regulation | MSSKSTKRAK | MSSKSTKRAKIEDPKDNVFMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCVEMLDEFEREFSKREKPIRKRHSQKPEPSEDQADPEEDKDEKKETNQNDKFSLEGKQLKCIVGLTKGPGELHFLCKFSDDTARLLPAKEVNSRYPSQVIRYYESKLTIQDPKADEL | chromatin organization chromosome attachment to the nuclear envelope dauer larval development determination of adult lifespan germ cell development gonad development negative regulation of gene expression negative regulation of Ras protein signal transduction negative regulation of vulval development nematode larval de... |
BMP signaling pathway mesodermal cell fate specification positive regulation of multicellular organism growth regulation of BMP signaling pathway regulation of dauer larval development regulation of multicellular organism growth | plasma membrane; receptor complex; side of membrane | coreceptor activity | Caenorhabditis elegans | Cell membrane Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Signal Transmembrane Transmembrane helix | MSIVYLVSIT | MSIVYLVSITFIFSVFKPITSCRVEECAAWFQKTKDYENLVPKATERYCQVLQTYLKCMNDTQRYCHGNLRFHSSELIMRRHWKEFECEKWESCNDNSHVKRKHVNTCYFNPPPSNRKLKYCSLFGDPHLIMFNGSVQTCSEEGARPLVDNRYFLVQVTNRNVRGEALTTTVTKVTVLVRKHNCTASLRYEASSDEEGLPRGFVDGTTFQMTSKHSVEVLWQDDNYVEIALHFIHSSIHIRRQGPYLSVSVRAPTIVLETGGDVARELCWSGCRKSSRIPAELAVEMTKKFAECYRRRVHVPKKVAEDRCKDIGNIGVFF... | BMP signaling pathway mesodermal cell fate specification positive regulation of multicellular organism growth regulation of BMP signaling pathway regulation of dauer larval development regulation of multicellular organism growth plasma membrane; receptor complex; side of membrane coreceptor activity Caenorhabditis eleg... |
defense response to bacterium determination of adult lifespan ecdysis, collagen and cuticulin-based cuticle molting cycle, collagen and cuticulin-based cuticle regulation of transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Caenorhabditis elegans | DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSFQLDQSTS | MSFQLDQSTSVIKTAPPGRLEFKNEPIDIASSNIQDLAKMQTLDGYYQQTSLQLPQSQQYHRMYENVYNNQQILYAQTQNFQYPSTLLTNGSLAQTEWRGQQMDTSAYSNTGYSRSSTSQQPQYTQQVTENERIVYKPVDMPSPVDSGIGGDISILNPKEEFFTSADGGSMLERSSERTLSHRDSPLVIPKLYNNLGFQYVLEAPISTSVRRDDDRMTYVNKGQFYTVSLEYTPDLNKCLKSQTVKSQLMVVFREDKTYEEEIKTWQSWHARQHVSKQRILEIDSKNSSGMIGQIEEIGNNAVQFYWNPSDPSGVRISIA... | defense response to bacterium determination of adult lifespan ecdysis, collagen and cuticulin-based cuticle molting cycle, collagen and cuticulin-based cuticle regulation of transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II c... |
anatomical structure development axon guidance cell differentiation locomotory behavior neuron fate specification positive regulation of transcription by RNA polymerase II regulation of backward locomotion regulation of forward locomotion regulation of transcription by RNA polymerase II | axon; cytoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Alternative splicing Cell projection Cytoplasm DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MSDEDEPLNF | MSDEDEPLNFSTSKATEESKEGILGVRSIFNTPLLFPPPMFNAGVISPHIAAALAMSFNQQRMNASVSPPLDHTTISVNSFPSMGSVKTDSPPTASSPTLCCAVCGDVSSGKHYGILACNGCSGFFKRSVRRRLIYRCQAGTGNCVVDKAHRNQCQACRLKKCLNKGMNKDAVQNERQPRNTATIRPALDMDPQNFFREYAGAVSAIMGHSNMMKREDSPSSASDGKTEDEKKDSLQETTMSQLESVLQWAQQFRLFTVLTNSEKRQIILTQWPRLLCISLCEQAEDVSFDDHLTSLMLKFRRLDVSPAEFNCLKAITIF... | anatomical structure development axon guidance cell differentiation locomotory behavior neuron fate specification positive regulation of transcription by RNA polymerase II regulation of backward locomotion regulation of forward locomotion regulation of transcription by RNA polymerase II axon; cytoplasm; nucleus DNA-bin... |
intracellular amino acid homeostasis L-amino acid transport protein localization to plasma membrane | amino acid transport complex; apical plasma membrane; microvillus membrane | protein-membrane adaptor activity | Caenorhabditis elegans | Alternative splicing Cell membrane Cell projection Membrane Reference proteome Repeat | MVHIPSDVTP | MVHIPSDVTPPRLCVVEKLNGENEYGYNLHAEKGRGQFVGTVDPDSPAERGGLITGDRIFAVNGHSIIGENHKKVVERIKANPNRCEMLVISEEGAKWYNENNVQITLDLPNIERVSPMSKETPVFVPPPPPPTDAMPYLPRLAELNKGTPDQEFGFNLHAERGRGHFIGTVDAGGIGEKAGLEAGQRIVGVNGQLIYPTTGHKEVVALIKKDTMKTTLLVASEDVDKYHKDHNIAYSWDNVERVDTRPVINVETHHHHEEVSVPKSNGYDVPPLNPHSIQVNEEREISKMTTTTRTETITNSNSAYQYKESSTAYDAYA... | intracellular amino acid homeostasis L-amino acid transport protein localization to plasma membrane amino acid transport complex; apical plasma membrane; microvillus membrane protein-membrane adaptor activity Caenorhabditis elegansAlternative splicing Cell membrane Cell projection Membrane Reference proteome Repeat MVH... |
dauer larval development determination of adult lifespan negative regulation of BMP signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of dauer larval development transforming growth factor beta receptor signaling pathway | cytoplasm; nucleus; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding SMAD binding | Caenorhabditis elegans | Nucleus Reference proteome | MSDSPIGSSQ | MSDSPIGSSQQVEPEHRTPDLMDIDPLIANLKALHEETRSDDDDDGQPSTSAKRKDSRADGIVIHQKKYSDPGRFLWIWLLGVRVPALSIDGEPHLPIEILDDMLTKKDKKDQMSFQNLLRYKNVYIRMASPSQFRAVMEKSKECENLNITSLSLMSRSDIERIMGELRLESMLTLAEHDNWDISDRVHVVHVNFIDYCSEWLESDDLEEDVMQSGTHGYWYKNRRNMRCIECQHCEGKFTPTDFIMHHHYPIKPSGFVHTGCNSFQWIRLIEVFDKSNENLEAWNKFVLNSHRAGKREYDEAAPHQAPPKRPAMETPVP... | dauer larval development determination of adult lifespan negative regulation of BMP signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of dauer larval development transforming growth factor beta receptor signaling pathway cytoplasm; nucleus; transcription regulator complex D... |
calcineurin-mediated signaling endocytosis | calcineurin complex; endoplasmic reticulum; sarcomere; striated muscle dense body | calcium ion binding calcium-dependent protein serine/threonine phosphatase regulator activity phosphatase binding | Caenorhabditis elegans | Calcium Cytoplasm Endocytosis Metal-binding Reference proteome Repeat | MGADASLPME | MGADASLPMEMCSNFDAYELRRLTRRFKKLDVDGSGSLSVEEFMSLPELQQNPLVQRVIDIFDEDGNGEVDFREFIQGISQFSVKGDKNTKLKFAFRIYDMDRDGFISNGELFQVLKMMVGNNLKDSQLQQIVDKTILFHDKDGDGKISFQEFCDVVEHTEVHKKMVLENI | calcineurin-mediated signaling endocytosis calcineurin complex; endoplasmic reticulum; sarcomere; striated muscle dense body calcium ion binding calcium-dependent protein serine/threonine phosphatase regulator activity phosphatase binding Caenorhabditis elegansCalcium Cytoplasm Endocytosis Metal-binding Reference prote... |
acyl-CoA metabolic process ascaroside biosynthetic process dauer entry dauer exit lipid transport negative regulation of lipid storage olfactory learning pheromone biosynthetic process positive regulation of developmental growth positive regulation of nematode larval development regulation of chemotaxis response to phe... | peroxisome | acyltransferase activity lipid binding propanoyl-CoA C-acyltransferase activity propionyl-CoA C2-trimethyltridecanoyltransferase activity | Caenorhabditis elegans | Lipid transport Lipid-binding Peroxisome Reference proteome Transferase Transport | MTPTKPKVYI | MTPTKPKVYIVGVGMTKFCKPGSVPGWDYPDMVKEAVTTALDDCKMKYSDIQQATVGYLFGGTCCGQRALYEVGLTGIPIFNVNNACASGSSGLFLGKQIIESGNSDVVLCAGFERMAPGSLENLAAPIDDRALSVDKHISVMSETYGLEPAPMTAQMFGNAAKEHMEKYGSKREHYAKIAYKNHLHSVHNPKSQFTKEFSLDQVINARKIYDFMGLLECSPTSDGAAAAVLVSEKFLEKNPRLKAQAVEIVGLKLGTDEPSVFAENSNIKMIGFDMIQKLAKQLWAETKLTPNDVQVIELHDCFAPNELITYEAIGLCP... | acyl-CoA metabolic process ascaroside biosynthetic process dauer entry dauer exit lipid transport negative regulation of lipid storage olfactory learning pheromone biosynthetic process positive regulation of developmental growth positive regulation of nematode larval development regulation of chemotaxis response to phe... |
centriole assembly embryo development ending in birth or egg hatching nematode larval development positive regulation of vulval development regulation of vulval development | cytosol; protein phosphatase type 2A complex | protein phosphatase regulator activity | Caenorhabditis elegans | Cytoplasm Reference proteome Repeat WD repeat | MVMEVDEPAV | MVMEVDEPAVAATTSQNQPQEHANDFDMDTSEGPIENDETFEPVDQINWKFNQVKGNIDADVHTEADVISCVEFSHDGEYLATGDKGGRVVIFQRDQSGKYVKGVRSREYNVYSTFQSHEPEFDYLKSLEIDEKINQIRWLKKKNAANFILSTNDKTIKLWKISERERKIGDDAWNLPRTNRINTSSFRGRLQIPSIVPMELIVEASPRRVYGNAHTYHVNSISVNSDQETFLSADDLRVNLWNLEITNESFNIVDIKPANMEELTEVITAAEFHPTQCNWFVYSSSKGSIRLCDMRDRALCDAYAKIFEEPEDPQSRSF... | centriole assembly embryo development ending in birth or egg hatching nematode larval development positive regulation of vulval development regulation of vulval development cytosol; protein phosphatase type 2A complex protein phosphatase regulator activity Caenorhabditis elegansCytoplasm Reference proteome Repeat WD re... |
carbohydrate biosynthetic process fucosylation protein glycosylation | Golgi cisterna membrane; Golgi membrane | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity glycoprotein 3-alpha-L-fucosyltransferase activity metal ion binding | Caenorhabditis elegans | Glycoprotein Glycosyltransferase Golgi apparatus Magnesium Manganese Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MTARSIKLFF | MTARSIKLFFARWKYLMFACCITYLLVIYAPISKSEQKDWKEGEIELSNDHELDVPILQKEELKPQQRPSFEENVPKKKTFNFNPVGKEPFDVEEVLTSSDIKLEERMTATVIPGQKRLILSWNAGHSQDNLQGCPDWNCEFTQVRARAPDADAVLIAHMDNDFVPKPNQYVVYFSQESPANSGIQIPRPDYINMTLGFRHDTPAGSPYGYTVKLGAKSRKTGQVVDANLVNGKAKGAAWFVSHCQTNSKREDFVKKLQKHLQIDIYGGCGPMKCARGDSKCDTMLDTDYHFYVTFENSICEDYVTEKLWKSGYQNTIIP... | carbohydrate biosynthetic process fucosylation protein glycosylation Golgi cisterna membrane; Golgi membrane 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity glycoprotein 3-alpha-L-fucosyltransferase activity metal ion binding ... |
anatomical structure development anterior/posterior pattern specification cell fate commitment negative regulation of distal tip cell migration nematode male tail mating organ morphogenesis nematode male tail tip morphogenesis positive regulation of glial cell differentiation positive regulation of transcription by RNA... | cytoplasm; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Nucleus Paired box Reference proteome Transcription Transcription regulation | MSDAGHTGVN | MSDAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTIRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLAAKKEQVTMQTELYDRIRIVDNFPYNSSWYGQWPIPMNGAVGLNPFVPAPLIEPKTEGEFEKDEDQKPPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSSLSNGTPTPTPGSVTGSNMTNPIGSPASTPN... | anatomical structure development anterior/posterior pattern specification cell fate commitment negative regulation of distal tip cell migration nematode male tail mating organ morphogenesis nematode male tail tip morphogenesis positive regulation of glial cell differentiation positive regulation of transcription by RNA... |
cell cycle cell differentiation embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis gonad development negative regulation of cell cycle G1/S phase transition negative regulation of DNA endoreduplication negative regulation of G1/S transition of mitotic cell cycle negative regulati... | chromatin; DRM complex; nucleus; Rb-E2F complex; transcription regulator complex | RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Cell cycle DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MPKRAADEPG | MPKRAADEPGTSTTDPFHEQSPFDAVLAGTETTDTICEEPPAKRIDLDIKQEFNGGVQSGGLIKNESELTQMTIKQETEGNINEARREEEDEEQDEDSRTSMPPALGEDDDYEEDDADSFIDKTNTPPPSQSFLEGCRAANLPNDIVTGAWETYNHAVQRVSLEGSESAWQLSAIYYYLLSKGIKRRGKTIRILIQPFPVSILTIANSFDISVAEMLDKTARFVEIIHSRKIRRYQEYIRRIQEGLAVSCVIFKKFCRIFCKIFEEIKVGSENCPSSHELFTVLWTSFLVMKSRMTVDDLISNYQLLFSILDQVYTEMCS... | cell cycle cell differentiation embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis gonad development negative regulation of cell cycle G1/S phase transition negative regulation of DNA endoreduplication negative regulation of G1/S transition of mitotic cell cycle negative regulati... |
hyperosmotic response locomotion phosphorylation stress-activated MAPK cascade | axon; cytoplasm; neuronal cell body; perikaryon | ATP binding exonuclease activity JUN kinase kinase activity MAP kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Caenorhabditis elegans | ATP-binding Cell projection Cytoplasm Kinase Magnesium Metal-binding Nucleotide-binding Reference proteome Serine/threonine-protein kinase Stress response Transferase Tyrosine-protein kinase | MENVCFQQRL | MENVCFQQRLRDLETRVRKWKFLKLGLTEVRLRPRDRRSTSVDQKHKECSSTSSSPQHQRPNNIGYLTSPMERKFTPLSMKPSPSRRDTEKDALEYEFLEGYKKSGTLEIDGEKQVVDPNEIHIISLLGSGSCGVVESATVRSKLMAVKTMYKNDNKENLKRILRDVRIMSMCNSPFIVTSYGYFMFDSSVKICMQIMSACCEKLLRRIYHSKLDFFPEFVAGHIVYSAISALDYLKEKHSIIHRDIKPSNILFDDSGNVKLCDFGISGFMTDSMAHSKSAGCPPYMAPERLTIETNSKYDVRSDVWSLGITVYQLVTGL... | hyperosmotic response locomotion phosphorylation stress-activated MAPK cascade axon; cytoplasm; neuronal cell body; perikaryon ATP binding exonuclease activity JUN kinase kinase activity MAP kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity protein tyrosine... |
animal organ morphogenesis epidermal cell differentiation hindgut morphogenesis nematode male tail tip morphogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to salt stress | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Metal-binding Nucleus Reference proteome Repeat Zinc Zinc-finger | MDSRVWLPLI | MDSRVWLPLIGAHLLPRDISVITQMIANNNNTSISRSSTNSSKPEEKNSKKFLIERFLDDDPSPPASILSPSPKAAIPSPIINPAVEFVNGGYGVKNPLAPLISSFETTSIPCSTVSPSSLISSSKDEFQDSLTCHICGKKFGLQRLLNRHIKCHSDLKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCEQCEKSFTQRCSLESHLRKVHGVTHQYAYKERRSKVFVCEDCGYTDEKFEVYLSHIKVVHPFSAAYLRFTQLQKKNSSMKPEQLSKISL | animal organ morphogenesis epidermal cell differentiation hindgut morphogenesis nematode male tail tip morphogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to salt stress nucleus DNA-binding transcription factor activity DNA-binding transcription factor activ... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway anterior/posterior pattern specification cell surface receptor signaling pathway embryo development ending in birth or egg hatching self proteolysis sexual reproduction | plasma membrane | carbohydrate binding endopeptidase activity G protein-coupled receptor activity transmembrane signaling receptor activity | Caenorhabditis elegans | Alternative splicing Cell membrane G-protein coupled receptor Glycoprotein Lectin Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MRRNKTTYSL | MRRNKTTYSLLQTILVACLLTVTPTFASNKPTTDESGTISHTICDGEAAELSCPAGKVISIVLGNYGRFSVAVCLPDNDIVPSNINCQNHKTKSILEKKCNGDSMCYFTVDKKTFTEDPCPNTPKYLEVKYNCVVPATTTTTTTTTSTTTTDSSLIVDEEEEAQKDALNSDVIKPVKKKEDVFCSATNRRGVNWQNTKSGTTSSAPCPEGSSGKQLWACTEEGQWLTEFPNSAGCESNWISSRNSVLSGVISSEDVSGLPEFLRNLGSETRRPMVGGDLPKVLHLLEKTVNVIAEESWAYQHLPLSNKGAVEVMNYMLRN... | adenylate cyclase-activating G protein-coupled receptor signaling pathway anterior/posterior pattern specification cell surface receptor signaling pathway embryo development ending in birth or egg hatching self proteolysis sexual reproduction plasma membrane carbohydrate binding endopeptidase activity G protein-coupled... |
membrane protein ectodomain proteolysis | endosome membrane; lysosomal membrane; plasma membrane | metal ion binding metalloendopeptidase activity | Caenorhabditis elegans | Alternative splicing Cell membrane Disulfide bond EGF-like domain Endosome Glycoprotein Hydrolase Lysosome Membrane Metal-binding Metalloprotease Protease Reference proteome Transmembrane Transmembrane helix Zinc | MTDTLDLKLS | MTDTLDLKLSSRRQWNPVRCPVRLEVDGSAQTPTSLVQTALNNPSFDLVIAAPNGQNVYIPFTEDRKLFTANIADDPSTSSLISHCHFEGVTEDGRHALSLCDPGEITGLLMTQTNRFGLSTSNNGSFVLIPYVENNCDLGSLVHSSSRKKRQIGKQNTVIDRNPSYIREHLDGRKRFVELALVADYSVYTKYDSDEKKVNDYMQQTMNILNSLYFPLNIRITLVHSEIWKKGDQISVIPDSKETLNNFMEYKKIMLKDHFFDTGYLMTTLKFDEGVVGKAYKGTMCSYDYSGGIYVDHNNDTVETVATFAHELGHTFGM... | membrane protein ectodomain proteolysis endosome membrane; lysosomal membrane; plasma membrane metal ion binding metalloendopeptidase activity Caenorhabditis elegansAlternative splicing Cell membrane Disulfide bond EGF-like domain Endosome Glycoprotein Hydrolase Lysosome Membrane Metal-binding Metalloprotease Protease ... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process determination of adult lifespan embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis lysosome organization nematode larval development positive regulation of brood size positive regulation of mul... | cytoplasm | orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity | Caenorhabditis elegans | Cytoplasm Decarboxylase Glycosyltransferase Lyase Multifunctional enzyme Pyrimidine biosynthesis Reference proteome Transferase | MSSLTDKTRN | MSSLTDKTRNGALKRNLLRQMLKASVFKFGEFQLKSGQISPIYIDLRECFGHPGLLMLISEAISKQVEISEVQYAGVLGIPYAALPYASVAAGNYLKKPLLIVRKEAKSYGTKKLIEGLYQPNDRLILIEDVVTTGGSILDVVKVLHTENLVASDVFCILDREQGGRQKLQDAGVTLHSLLDMQTVLTFLYSTGAIGDEQWHGIVQALNLPYTSPTKLEINSELENLSSLPYVENVRTPLAERESLTESALIKKILGIMRRKKSNLCLAVDYTTVEQCLQMIELAGPFVLAIKLHADAITDFNEEFTRKLTTMANDMDFI... | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process determination of adult lifespan embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis lysosome organization nematode larval development positive regulation of brood size positive regulation of mul... |
chemosensory behavior chemotaxis dauer larval development dephosphorylation determination of adult lifespan learning or memory lipid metabolic process positive regulation of dauer larval development positive regulation of insulin receptor signaling pathway positive regulation of positive chemotaxis protein import into ... | axon; cytoplasmic side of plasma membrane; cytosol; dendrite; neuronal cell body; nucleus; perikaryon; plasma membrane; protein phosphatase inhibitor complex | lipid binding myosin phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity protein tyrosine phosphatase activity | Caenorhabditis elegans | Cell membrane Cell projection Cytoplasm Hydrolase Lipid metabolism Lipid-binding Membrane Nucleus Phosphoprotein Protein phosphatase Reference proteome | MVTPPPDVPS | MVTPPPDVPSTSTRSMARDLQENPNRQPGEPRVSEPYHNSIVERIRHIFRTAVSSNRCRTEYQNIDLDCAYITDRIIAIGYPATGIEANFRNSKVQTQQFLTRRHGKGNVKVFNLRGGYYYDADNFDGNVICFDMTDHHPPSLELMAPFCREAKEWLEADDKHVIAVHCKAGKGRTGVMICALLIYINFYPSPRQILDYYSIIRTKNNKGVTIPSQRRYIYYYHKLRERELNYLPLRMQLIGVYVERPPKTWGGGSKIKVEVGNGSTILFKPDPLIISKSNHQRERATWLNNCDTPNEFDTGEQKYHGFVSKRAYCFMVP... | chemosensory behavior chemotaxis dauer larval development dephosphorylation determination of adult lifespan learning or memory lipid metabolic process positive regulation of dauer larval development positive regulation of insulin receptor signaling pathway positive regulation of positive chemotaxis protein import into ... |
fucosylation protein glycosylation | Golgi cisterna membrane | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity metal ion binding | Caenorhabditis elegans | Calcium Glycoprotein Glycosyltransferase Golgi apparatus Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MKHNTLRAVF | MKHNTLRAVFQFSFFIGICTFIMIAGYSYQINYNQRMGIFYGGNITFKKVPKVVIYTATPFFDVPIENSILRDCSEKIKNSCTVTSNNKTFPIADAIVFHSRDINETKLSFFNKNRRYDIPYIMMAMENPFFAGLTVYHNFFNWTMTYRTDSDIFHPYGAFVKSYVPAEVNYSEIWNSKTKETLWMVSNGNAQNKRKELVEKLIKKGMSIDLYGQLYKKEPAECPRRRGPPGCDVKFHSPYKFAIAFENSNCKDYVTEKFWKKAGIYKTVPIVMSRKIYRDLGIPDSMYIAVDDYPNLEEFVHHIQNVTSNEEEYMKYHK... | fucosylation protein glycosylation Golgi cisterna membrane 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity metal ion binding Caenorhabditis elegansCalcium Glycoprotein Glycosyltransferase Golgi apparatus Membrane Metal-binding Reference proteome Signal-anchor Transferase Transmembrane Transmemb... |
defense response to Gram-negative bacterium determination of adult lifespan endoplasmic reticulum unfolded protein response ERAD pathway IRE1-mediated unfolded protein response lipid homeostasis positive regulation of transcription by RNA polymerase II response to endoplasmic reticulum stress response to heat response ... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing DNA-binding Nucleus Reference proteome Transcription Transcription regulation Ubl conjugation | MSNYPKRIYV | MSNYPKRIYVLPARHVAAPQPQRMAPKRALPTEQVVAQLLGDDMGPSGPRKRERLNHLSQEEKMDRRKLKNRVAAQNARDKKKERSAKIEDVMRDLVEENRRLRAENERLRRQNKNLMNQQNESVMYMEENNENLMNSNDACIYQNVVYEEEVVGEVAPVVVVGGEDRRAFESAAFINEPQQWEQARSTSINNNISNQLRRMDSKKNNTISVDMYLTIISILCNHMDRNKKMDTSNKSSNISRAQAESSIDSLLATLRKEQTVMQRLVQADPCTHLQKRVKHFRRIP | defense response to Gram-negative bacterium determination of adult lifespan endoplasmic reticulum unfolded protein response ERAD pathway IRE1-mediated unfolded protein response lipid homeostasis positive regulation of transcription by RNA polymerase II response to endoplasmic reticulum stress response to heat response ... |
cell differentiation nervous system development positive regulation of transcription by RNA polymerase II regulation of neuron differentiation regulation of synapse organization regulation of transcription by RNA polymerase II regulation of transcription elongation by RNA polymerase II | chromatin; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | DNA-binding Homeobox Neurogenesis Nucleus Reference proteome | MQSTQISSTT | MQSTQISSTTVILPSEVIQPPQQSAVPSEFKNTLPSRLNLFEGFDQSFSELTNPYQPVIPLMQRESLLGASSYYSSPSQNQRSYQNHRQHSNPDTINLRSQQQKRKPRVLFTQHQVNELEERFKKQRYVTATEREELAQCLGLTATQVKIWFQNRRYKCKRLAQDRTLQLSQIPFNPMFASAFPFGINSFGTAPSSSSSGS | cell differentiation nervous system development positive regulation of transcription by RNA polymerase II regulation of neuron differentiation regulation of synapse organization regulation of transcription by RNA polymerase II regulation of transcription elongation by RNA polymerase II chromatin; nucleus DNA-binding tr... |
anterior/posterior axis specification, embryo cell differentiation commissural neuron axon guidance embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis endodermal cell fate specification establishment of mitotic spindle orientation gonad morphogenesis innate immune response left/r... | cell projection; contractile fiber; extrinsic component of cytoplasmic side of plasma membrane; phagocytic cup | ATP binding metal ion binding netrin receptor binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding | Caenorhabditis elegans | Alternative splicing ATP-binding Cell membrane Cell projection Kinase Lipoprotein Magnesium Manganese Membrane Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MGCLFSKERR | MGCLFSKERRSGGSDMGVSERIDVSRFQTPQQQTVFHVNNGGNEGTISQLNGTSDGMMGNGRGGGGGGGAQERETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKL... | anterior/posterior axis specification, embryo cell differentiation commissural neuron axon guidance embryo development ending in birth or egg hatching embryonic digestive tract morphogenesis endodermal cell fate specification establishment of mitotic spindle orientation gonad morphogenesis innate immune response left/r... |
associative learning axonogenesis dauer larval development negative adaptation of signaling pathway neuron differentiation olfactory learning positive regulation of dauer larval development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of axon ex... | axon; nucleus; perikaryon | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing Cell projection DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MYFQSLSADP | MYFQSLSADPLDSVNTTTDFNQLAQLLLMLTNSSSKETIATHVVTNSVPSAFQFDWSSHFKEEYDLVEKLNSPQYTNLTSISPSSSTDSNNLILRQIQIPKIEPALLNQCCLCTFAIVDKEISVVDGKYYHNNCLRCQMCDIPFEYSDKCYVRDGVFLCRADHAKRYQKCCRKCEIPLNREDMVMKAKEMIFHHACFVCFICGIKLNPGDYYTMSPQGHLYCHAHYNAVRSTVLCEEAAVATVPAVVAPPPPPPTTTTAPPPAAPEQPPREASTEAEASTDEDGNGSGSQRSKRMRTSFKHHQLRAMKTYFALNHNPDAK... | associative learning axonogenesis dauer larval development negative adaptation of signaling pathway neuron differentiation olfactory learning positive regulation of dauer larval development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of axon ex... |
lipid transport malate transmembrane transport oxaloacetate transport phosphate ion transmembrane transport succinate transmembrane transport sulfate transport thiosulfate transport | mitochondrial inner membrane | antiporter activity malate transmembrane transporter activity oxaloacetate transmembrane transporter activity succinate transmembrane transporter activity sulfate transmembrane transporter activity thiosulfate transmembrane transporter activity | Caenorhabditis elegans | Acetylation Antiport Lipid transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAEDKTKRLG | MAEDKTKRLGRWYFGGVAGAMAACCTHPLDLLKVQLQTQQQGKLTIGQLSLKIYKNDGILAFYNGVSASVLRQLTYSTTRFGIYETVKKQLPQDQPLPFYQKALLAGFAGACGGMVGTPGDLVNVRMQNDSKLPLEQRRNYKHALDGLVRITREEGFMKMFNGATMATSRAILMTIGQLSFYDQIKQTLISSGVAEDNLQTHFASSISAASVATVMTQPLDVMKTRMMNAAPGEFKGILDCFMFTAKLGPMGFFKGFIPAWARLAPHTVLTFIFFEQLRLKFGYAPPVKA | lipid transport malate transmembrane transport oxaloacetate transport phosphate ion transmembrane transport succinate transmembrane transport sulfate transport thiosulfate transport mitochondrial inner membrane antiporter activity malate transmembrane transporter activity oxaloacetate transmembrane transporter activity... |
cell fate specification neuron differentiation positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of neuron differentiation regulation of transcription by RNA polymerase II serotonin biosynthetic process | nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Alternative splicing DNA-binding Homeobox LIM domain Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc | MDAHLVQAKK | MDAHLVQAKKTSTASELSDSSLTFPFIGDYLSSPSLTTSDYVSDCSNLTVEGPVPANQEFSSSDESSVYISSALRLADYAFTPDDNIRIKPDAVIVICTQCQHQIQDKFFLSIDGRNYHENCLQCSTCENPLSNKCFYKDKTFYCKGCYFRTHVTSTASSCRELGPKCASCDRTIQATDWVRRARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLCKQHFLELVEGDSGVSSQKAKTKRVRTTFAEDQLSVLQTYFNRDSNPDGADLEKIASMTGLSKRVTQVWFQNSRARQKKWHQKSEGDNGDSQRSSVGPSSPSQ... | cell fate specification neuron differentiation positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of neuron differentiation regulation of transcription by RNA polymerase II serotonin biosynthetic process nucleus DNA-binding transcription factor activity DNA-bi... |
G protein-coupled receptor signaling pathway positive regulation of protein secretion signal transduction sleep | plasma membrane | G protein-coupled receptor activity | Caenorhabditis elegans | Alternative splicing Cell membrane G-protein coupled receptor Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MESQQLMACA | MESQQLMACAILVIVLVGIFGNSLSFILFSRPHMRSSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLSTYMAYILKLIYPINLMMQTCSVYIMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVIIVSAFLYNFVRFFEYRFVVTESGALYEKWLRDPGKHRWYYVGYYTILYIVTHFLVPFSVMAFANGHVIVAMCKLSKTRQMLTRQQQREQSTTVMLLIVTFVFAICNTLPFLLNVSESIFPTLFQDESTRGLAYWLNDLSNLLVVLNSGTTFIIYFTFSEKYRQTLVFILKNGCCATVSDYNNYTAM... | G protein-coupled receptor signaling pathway positive regulation of protein secretion signal transduction sleep plasma membrane G protein-coupled receptor activity Caenorhabditis elegansAlternative splicing Cell membrane G-protein coupled receptor Membrane Receptor Reference proteome Transducer Transmembrane Transmembr... |
negative regulation of locomotion neuropeptide signaling pathway second-messenger-mediated signaling | extracellular space | neuropeptide receptor binding | Caenorhabditis elegans | Amidation Cleavage on pair of basic residues Neuropeptide Reference proteome Repeat Secreted Signal | MLGSRFLLLA | MLGSRFLLLALGLLVLVLAEESAEQQVQEPTELEKSGEQLSEEDLIDEQKRTPMQRSSMVRFGRSPMQRSSMVRFGKRSPMQRSSMVRFGKRSPMQRSSMVRFGKRSPMERSAMVRFGRSPMDRSKMVRFGRSSIDRASMVRLGKRTPMQRSSMVRFGKRSMEFEMQSNEKNIEDSE | negative regulation of locomotion neuropeptide signaling pathway second-messenger-mediated signaling extracellular space neuropeptide receptor binding Caenorhabditis elegansAmidation Cleavage on pair of basic residues Neuropeptide Reference proteome Repeat Secreted Signal MLGSRFLLLA MLGSRFLLLALGLLVLVLAEESAEQQVQEPTELEKS... |
anterior/posterior pattern specification asymmetric neuroblast division asymmetric protein localization involved in cell fate determination cell fate determination dopaminergic neuron differentiation neuron apoptotic process neuron migration positive regulation of transcription by RNA polymerase II protein localization... | cell cortex; cytoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific | Caenorhabditis elegans | Cytoplasm Nucleus Reference proteome | MTYLAVVLNG | MTYLAVVLNGPKAKNGRKVFDSFLEQNRQMFWNRELTSACESITYMGFMRPGTLFVSGPASQLTVLKDAWARRILKPAMGYTITSLGDLGAIQQVEQMHFVPLGDVICDAVAQLNRQGLAATEQAIRQYVARHCPHVAPPGIEMVRQTITSLLSTGFVYKMADHYFVSVPTNSPMRPPAKAATKTTKTTVECQTGASMMCPQQTSTSSDEHVIEPAKKDHKKCQNSNRRSIFARLFSRGMKPQTIMPSASPIHVGGPPTPPPAAMLPTKNKYPTYHHDLNEECQRKARRRNHPRRGETQKLLSSSSECLKYYPVDMPETR... | anterior/posterior pattern specification asymmetric neuroblast division asymmetric protein localization involved in cell fate determination cell fate determination dopaminergic neuron differentiation neuron apoptotic process neuron migration positive regulation of transcription by RNA polymerase II protein localization... |
defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium negative regulation of gene expression positive regulation of gene expression positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of gene expression | nucleus | ATP binding DNA-binding transcription factor binding mitogen-activated protein kinase kinase binding protein kinase activity | Caenorhabditis elegans | ATP-binding Nucleotide-binding Nucleus Reference proteome | MARTKCKTKT | MARTKCKTKTVANPRTGVRKTAKDLSEPVRQDAVSRRRPTTLPFVGNTSSRPRVFYDVLAKKNVVFPNVKAEYHYRVRNAPKIDPKNFGTTLPICYSSIGPAKTLELRPLGRLPPHIIKALNDHYVQLTRGSMVPAADLYNNGDHPAEQRIPTMLNENEYLRLIQELEEEEKSKQFSATSSSAPHVNPYSAQHLVNGEIIGIFVIYGTGLVTRAVCSQTREMFTAHVLPEWKASKVIDVIRRLQIPTDISSMTADEIRLSELCISKRMEIIKSNDRYILMNPCESATIHSYATERLDEITENDVMSIYQKVVEIVRFCHS... | defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium negative regulation of gene expression positive regulation of gene expression positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of gene expression nucleus ATP bind... |
fucosylation protein glycosylation | Golgi cisterna membrane | alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity | Caenorhabditis elegans | Glycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MSQIGGATCT | MSQIGGATCTWRYLGRFVTLGIYASVALFVWYTLVPTRSKHKDSIAINNNNADPATALIPVHTKNVVIYAATKFFGHPITTERFLATCPDVQNYCRITQEESEFDNADAVLFHNADYRGSTDKFKKMKSQRKPGVPYVLWSLESPTNDMFRPDSHMINWTMTYRTDSDVWAPYGTIVKLKNPVEVDLNAIWEGKTKTATWLASNCITQNHRFDLIKKIIDNGFEIDIWGNCGKQVSQCAGVDNQESPCVLELIKPYKFYISMENSNCKDYVTEKFWKALNDRMTIPIVLARKYYKDLGVPDSAYIAVDDYATLDEFLAHV... | fucosylation protein glycosylation Golgi cisterna membrane alpha-(1->3)-fucosyltransferase activity fucosyltransferase activity Caenorhabditis elegansGlycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MSQIGGATCT MSQIGGATCTWRYLGRFVTLGI... |
negative regulation of transcription by RNA polymerase II positive regulation of nematode male tail tip morphogenesis regulation of gene expression regulation of transcription by RNA polymerase II tissue development | CCAAT-binding factor complex; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity | Caenorhabditis elegans | DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MNGASRGDVQ | MNGASRGDVQRPTPVQAPAKRPIPPTVFRFEKASKIGTSLDTTPKELPIRRPVPLPGPRFVKDVNPSPPATSSPNVQTQCHQPPVVRSQTHQASVSQTTPTQTTPSQYTPASVSTARAPQFHRSSHVTPSQQQRIEQAFGPAPVSQSQPQNGSYIQYNEPSTSVASTTTSFYSPNESEPVFTHAISFKPNEPENGQKAREQLELLDSGKINEINQSKVPTTIELPPNCKLFQYSWVLDGIPRTLLVPMPMDATEEDVKAMLPKTLEMDSNLFNNARPRDELPVLSFPNGTVPNVEMIGPKVQQPMLVNPKQFNRIMRRRE... | negative regulation of transcription by RNA polymerase II positive regulation of nematode male tail tip morphogenesis regulation of gene expression regulation of transcription by RNA polymerase II tissue development CCAAT-binding factor complex; nucleus DNA binding DNA-binding transcription factor activity, RNA polymer... |
embryo development ending in birth or egg hatching locomotion mechanosensory behavior mRNA splicing, via spliceosome muscle organ morphogenesis nematode larval development neuron development regulation of alternative mRNA splicing, via spliceosome RNA splicing | nucleus; precatalytic spliceosome; U2-type precatalytic spliceosome | identical protein binding protein homodimerization activity | Caenorhabditis elegans | 3D-structure mRNA processing mRNA splicing Nucleus Reference proteome Repeat Spliceosome WD repeat | MSSIEIESSD | MSSIEIESSDVIRLIEQFLKESNLHRTLAILQEETNVSLNTVDSIDGFCNEITSGNWDNVLKTVQSLKLPAKKLIDLYEHVIIELVELRELATARLVARQTDPMILLKQIDPDRFARLESLINRPYFDGQEVYGDVSKEKRRSVIAQTLSSEVHVVAPSRLLSLLGQSLKWQLHQGLLPPGTAIDLFRGKAAQKEQIEERYPTMMARSIKFSTKSYPESAVFSPDANYLVSGSKDGFIEVWNYMNGKLRKDLKYQAQDNLMMMDAAVRCISFSRDSEMLATGSIDGKIKVWKVETGDCLRRFDRAHTKGVCAVRFSKDNS... | embryo development ending in birth or egg hatching locomotion mechanosensory behavior mRNA splicing, via spliceosome muscle organ morphogenesis nematode larval development neuron development regulation of alternative mRNA splicing, via spliceosome RNA splicing nucleus; precatalytic spliceosome; U2-type precatalytic spl... |
basement membrane disassembly body morphogenesis cell fate specification embryo development ending in birth or egg hatching germ-line stem cell population maintenance gonad development gonad morphogenesis nematode larval development nematode male tail tip morphogenesis neuroblast fate specification neuron development n... | cytoplasm; nucleus; RNA polymerase II transcription regulator complex | bHLH transcription factor binding DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA bind... | Caenorhabditis elegans | Developmental protein DNA-binding Neurogenesis Nucleus Reference proteome Transcription Transcription regulation | MADPNSQLTS | MADPNSQLTSATTVATAAIAQPQVMLPNAYDYPYNIDPTTIQMPDYWSGYHLNPYPPMQTTDIDYSSAFLPTHPPTETPASVAAPTSATSDIKPIHATSSTSTTAPSTAPAPTSTTDVLELKPTTAPATNSAETSAIVAPQPLTNLTAPIDAMSSMYTWPQTYPGYLPPSEDNKASEAVNPYISIPPTYTFGADPSVADFSSYQQQLAGQPNGLGGDTNLVDYNHQFPPAGMSPHFDPNGYPGMTGMPPGSSASSVRNDKSASRATSRRRVQGPPSSGIPTRHSSSSRLSDNESMSDDKDTDRRSQNNARERVRVRDINS... | basement membrane disassembly body morphogenesis cell fate specification embryo development ending in birth or egg hatching germ-line stem cell population maintenance gonad development gonad morphogenesis nematode larval development nematode male tail tip morphogenesis neuroblast fate specification neuron development n... |
determination of adult lifespan positive regulation of transcription by RNA polymerase II | nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | DNA binding DNA-binding transcription factor activity protein domain specific binding protein heterodimerization activity | Caenorhabditis elegans | Coiled coil DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSDMSDLEDD | MSDMSDLEDDQTGHCGSGEHSGPFDPKRHAREQHNALERRRRDNIKDMYTSLREVVPDANGERVQASRAVILKKAIESIEKGQSDSATLSVDVAEQESKNAKLREEIARLKAKKDPSSSQSIIQ | determination of adult lifespan positive regulation of transcription by RNA polymerase II nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex DNA binding DNA-binding transcription factor activity protein domain specific binding protein heterodimerization activity Caenorhabditis e... |
programmed cell death proteolysis | cytoplasm; external side of apical plasma membrane; extracellular region; lysosome | aspartic-type endopeptidase activity | Caenorhabditis elegans | Aspartyl protease Cytoplasm Disulfide bond Glycoprotein Hydrolase Lysosome Necrosis Protease Reference proteome Secreted Signal | MQTFVLLALV | MQTFVLLALVAACSAAVIQVPTHKTESLRAKLIKEGKYTAFLASQHAARAQQLNTGFQPFVDYFDDFYLGNITLGTPPQPATVVLDTGSSNLWVIDAACKTQACNGYPDSGYTKQKFDTTKSTTFVKETRKFSIQYGSGSCNGYLGKDVLNFGGLTVQSQEFGVSTHLADVFGYQPVDGILGLGWPALAVDQVVPPMQNLIAQKQLDAPLFTVWLDRNLQIAQGTPGGLITYGAIDTVNCAKQVTYVPLSAKTYWQFPLDAFAVGTYSETKKDQVISDTGTSWLGAPNTIVSAIVKQTKAVFDWSTELYTVDCSTMKTQP... | programmed cell death proteolysis cytoplasm; external side of apical plasma membrane; extracellular region; lysosome aspartic-type endopeptidase activity Caenorhabditis elegansAspartyl protease Cytoplasm Disulfide bond Glycoprotein Hydrolase Lysosome Necrosis Protease Reference proteome Secreted Signal MQTFVLLALV MQTFV... |
collagen and cuticulin-based cuticle development exosomal secretion multicellular organismal-level water homeostasis nematode larval development regulation of secretion vacuolar acidification | apical plasma membrane; cell body membrane; cytoplasmic vesicle; exocytic vesicle; multivesicular body; multivesicular body membrane; plasma membrane; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | ATPase binding proton-transporting ATPase activity, rotational mechanism | Caenorhabditis elegans | Cell membrane Endosome Glycoprotein Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MGSLSRSEEM | MGSLSRSEEMRFCQLIVEKDAAFNIVAEIGKQPYVQFKDLNPNVNSFQRTFVKDIRRYDEMERKLRFLESQIVKDEIVIPGRVDTGDYTILPTSELNTLEGTLTELEKDVKSMNDSDSQLKANFMDLKEWDAVLDKTDEFFQGGVDDQAQEELENLDEEGAVPRVEKGPVNYLVGIIRRERLNGFERVLWRACHHTAYIRSSDIEEELEDPGTGEKVHKSVFIIFLKGDRMRSIVEKVCDGFKAKLFKNCPKTFKERQSARNDVRARIQDLQTVLGQTREHRFRVLQAAANNHHQWLKQVRMIKTVFHMLNLFTFDGIGR... | collagen and cuticulin-based cuticle development exosomal secretion multicellular organismal-level water homeostasis nematode larval development regulation of secretion vacuolar acidification apical plasma membrane; cell body membrane; cytoplasmic vesicle; exocytic vesicle; multivesicular body; multivesicular body memb... |
locomotion mechanosensory behavior negative regulation of transcription by RNA polymerase II nervous system development positive regulation of transcription by RNA polymerase II positive regulation of vulval development protein localization to nucleus synapse assembly vulval development | nucleus; transcription regulator complex | DNA-binding transcription factor activity DNA-binding transcription factor binding LIM domain binding | Caenorhabditis elegans | Alternative splicing Reference proteome | MYGHHPDYGY | MYGHHPDYGYGNYGHPPPFAGPESSNSHYGMPPSQGTNSQNNMMMRSQATEPQPIGNTVSPLEFRIHDMNRRLYIFSSTGVSENDQQQWWDAFSHEFFDDDCKLWFVIGSEPVAFASRERYIINRQFIPKFFRSIFDSGMRELQYVLRGPSRECTLANGSQAYENENVLQITRYDQSSQFEVNTEGKLYVEFAPFDEVMNYRIKAWTLELKRSNEFVYNQNTADYRVEAQNPEQENKPRMGFFKSTFNLMTMLKILDPMQSIMSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQR... | locomotion mechanosensory behavior negative regulation of transcription by RNA polymerase II nervous system development positive regulation of transcription by RNA polymerase II positive regulation of vulval development protein localization to nucleus synapse assembly vulval development nucleus; transcription regulator... |
BMP signaling pathway defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium innate immune response nematode larval development nematode male tail tip morphogenesis positive regulation of cell size positive regulation of DNA endoreduplication positive regulati... | extracellular space | BMP receptor binding cytokine activity growth factor activity | Caenorhabditis elegans | Developmental protein Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MNDSVRTTTT | MNDSVRTTTTISSTKSLVHSFQLSAILHLFLLISFTPMSAAADQHASHATRRGLLRKLGLEHVPVQTGPSIDVPQHMWDIYDDDNDVDWVRHYYPKEIIEDNEGFLLSYNLSLAARNAHNEEVTKATLKLRLRRNNKARRSGNISIYFFEDDINNDRFQIESRSVDNLTEWIDFDVTAAFLRRTNRISFFIDLPEDVEIEETQSSSLSSLPYARAQSAPLIVFSDLSEPSSVRRKRSAQTGNSERKNRKKGRKHHNTEAESNLCRRTDFYVDFDDLNWQDWIMAPKGYDAYQCQGSCPNPMPAQLNATNHAIIQSLLHSL... | BMP signaling pathway defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium innate immune response nematode larval development nematode male tail tip morphogenesis positive regulation of cell size positive regulation of DNA endoreduplication positive regulati... |
anatomical structure development cell differentiation regulation of gene expression regulation of transcription by RNA polymerase II S-adenosylmethionine cycle | nucleus | nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MTPQSSPSSS | MTPQSSPSSSRDHVCLVCQDFASGYHYGVPSCVGCKTFFRRTIMKKQKYICQFEGNCPVDKTIRCACRYCRFEKCLSVGMDRNALQQNRDPIGYTKRTRRPKKELKTTSDCSSDEGASTPPSVSPLQLSPPPISPLLFQAAPLKPRRCILQTLAEREKCANDLRLSEYLPIRSLHEALCSKALLNDTAFLEKWGQPSERHQIFDLRFVNHDDYHYWHERDWFLLTEYAKTFDVFEALDYQDKAELVRHAAITVPVLVQVWNSPDYGPDTIVFPDGAYFDRTPEPTRPAGLNRKKYQMLDLVLKPFRDLQLDATEFAAFKA... | anatomical structure development cell differentiation regulation of gene expression regulation of transcription by RNA polymerase II S-adenosylmethionine cycle nucleus nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Caenorhabditis elegansAlternative splic... |
endodermal cell fate specification negative regulation of gene expression, epigenetic negative regulation of Ras protein signal transduction | cytosol; nucleus | mitogen-activated protein kinase binding mitogen-activated protein kinase kinase kinase binding protein kinase activator activity protein serine/threonine phosphatase activity | Caenorhabditis elegans | Reference proteome | MGDDGFLDQY | MGDDGFLDQYPANTDAGIGTVHSCRYSKQKNPVQNNDFLSCSMCIHNGPIKLYGIFSGFNGGDSTAKFVMNRLVYEIFGENPITPTLLPYQVVEEFKRKFENVAERYLLMNTDDLNNRLLKLEEQSETGNNAVSEINQKIRQGTTAIVVMIINQDLYVLNCGNSLAIAMNSENVVQLNSNLHNNDNPLEIVRIKGLGINPETVLNPTRAIGDLQRTHLFEETEAFKNAKGPPVISTPDVQYTKIDPSWRHLVLISDGVVQNLKEVEVENIPTEVSVRLIEDHTVTSTAQALVDSFARKHRDAYTMSDDKNFCISNHREEM... | endodermal cell fate specification negative regulation of gene expression, epigenetic negative regulation of Ras protein signal transduction cytosol; nucleus mitogen-activated protein kinase binding mitogen-activated protein kinase kinase kinase binding protein kinase activator activity protein serine/threonine phospha... |
phosphatidylcholine catabolic process phosphatidylinositol catabolic process phosphatidylinositol metabolic process regulation of asymmetric cell division regulation of protein localization | cytoplasm; cytosol; endoplasmic reticulum; nucleus; phosphatase complex | calcium-independent phospholipase A2 activity identical protein binding metal ion binding phosphatidic acid binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-4-phosphate binding phosphatidylserine binding phospholipase A1 activity phospholipase activity | Caenorhabditis elegans | Alternative splicing Hydrolase Lipid metabolism Phospholipid metabolism Reference proteome | MSGSEEEHLV | MSGSEEEHLVSLTFRKNEEDMDEDEGKVKQKEKPKEKQMEFVNQNFVESTEDESEVSTPTAVGLPIGTSTPDGDETPTQPDPNGKYTMAQTKDADLSRPSGLPSNGNPGSSTTVPPASKSGPVAPPRPSGTPVAPQRNRRRKVTELKCSEVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKDDSKEIRRGSWFSPDYQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSV... | phosphatidylcholine catabolic process phosphatidylinositol catabolic process phosphatidylinositol metabolic process regulation of asymmetric cell division regulation of protein localization cytoplasm; cytosol; endoplasmic reticulum; nucleus; phosphatase complex calcium-independent phospholipase A2 activity identical pr... |
cell differentiation epithelial tube morphogenesis hyperosmotic response meiotic cell cycle multicellular organismal-level water homeostasis phosphorylation positive regulation of gene expression spermatogenesis | cytoplasm; nucleus | ATP binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | Alternative splicing ATP-binding Cytoplasm Developmental protein Differentiation Kinase Meiosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Spermatogenesis Transferase | MSSSNLAGNT | MSSSNLAGNTNTTTTSSAASAAAAHSAANASTITSEYSTTQTTTGTFNTDTLSSIGSTSTLHGSQPSQPPPPPPPQVSSPIAAAAAASAALVAQLNPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTA... | cell differentiation epithelial tube morphogenesis hyperosmotic response meiotic cell cycle multicellular organismal-level water homeostasis phosphorylation positive regulation of gene expression spermatogenesis cytoplasm; nucleus ATP binding protein kinase binding protein serine kinase activity protein serine/threonin... |
anterior/posterior pattern specification epidermal cell fate specification negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis neuron development regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | DNA-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation | MVLISTPPPA | MVLISTPPPAYAHNRKTSQEKKRRDEINAKIKELQLLIQNESDNEKMTQGDVLNRAVEVVSRMETESPGPSSNPNRKGFFDGFRSIESLTYSFIKSLGVNSDVCQDFVQRAKQFFDRERSSLLSTVSGKSKRRSESEILHSSMSYRSQSSSPSTSESGITIDRKEVKKNREQDRRDRQGEAFDALKNFIIENKLMTSHQVEKMQRLNTLDIIIAYIQNKKHNFVSRSDQEQSLYAHAIAEGKKTAKNIAFQFFKSDRHLVVRCADLEKFFEFSLSPKPLFGFPSMPIPIPPPSFPIFPFRPFPFFPMPMAPMATSPKSQQ... | anterior/posterior pattern specification epidermal cell fate specification negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis neuron development regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA ... |
chromatin organization germ cell development gonad development negative regulation of gene expression negative regulation of Ras protein signal transduction negative regulation of transcription by RNA polymerase II negative regulation of vulval development nematode larval development positive regulation of growth rate ... | heterochromatin; nucleus; pericentric heterochromatin | chromatin binding enzyme binding methylated histone binding | Caenorhabditis elegans | Chromatin regulator Nucleus Reference proteome Transcription Transcription regulation | MSRQNPVRST | MSRQNPVRSTRGNSLRAREAQQAQDAPLFQESSSNVFVVEKVLNKRLTRGGSEYYIKWQGFPESECSWEPIENLQCDRMIQEYEKEAAKRTTRKRRYSPQPSTSSSAELQPSTSDEWAGKTLKTIIGITKAPGELHFLCKFSDDSVHLIPLREANVRFPSQVIKFYETRLVLQGVSPTIPGGMS | chromatin organization germ cell development gonad development negative regulation of gene expression negative regulation of Ras protein signal transduction negative regulation of transcription by RNA polymerase II negative regulation of vulval development nematode larval development positive regulation of growth rate ... |
microtubule depolymerization mitotic nuclear membrane disassembly negative regulation of axon extension involved in regeneration negative regulation of axon regeneration negative regulation of mitotic spindle elongation regulation of ARF protein signal transduction regulation of microtubule cytoskeleton organization re... | cell cortex; microtubule minus-end; plasma membrane | guanyl-nucleotide exchange factor activity phospholipid binding | Caenorhabditis elegans | Alternative splicing Cell membrane Cytoplasm Guanine-nucleotide releasing factor Membrane Reference proteome | MAKVASSGAE | MAKVASSGAEEALATIDGAPRRNVKKSEAFVMSGDVLISLNRNVSSTYAKLLGDQLPPGTTVASSIHPHQLSRATASAGVSFPSMNRNGAAAQKLSRLPVPVSTSQIERRGSLARKTSEESSPTAIRMLKTAPIERMESTDVEESEEETVMMTTDEKENQKKPNENDDEVMVVDEEQFIVVSNDMKSPNEEIVAKSLRSAMFTMPTDNHHHSYNSSPQISTLSPHLRSNGDGPSRSPVYDDVDDDLNGSLDAKDMSNNSHQQSFRSPENYSEKDTPSKHSVVTIDGSGVSNHYDQDGMFSHVYYSTQDTTPKHGSPSLRK... | microtubule depolymerization mitotic nuclear membrane disassembly negative regulation of axon extension involved in regeneration negative regulation of axon regeneration negative regulation of mitotic spindle elongation regulation of ARF protein signal transduction regulation of microtubule cytoskeleton organization re... |
methylation negative regulation of gene expression, epigenetic | heterochromatin; nuclear lamina | double-stranded DNA binding histone H3K9 methyltransferase activity histone H3K9 monomethyltransferase activity histone methyltransferase activity metal ion binding | Caenorhabditis elegans | Chromosome Metal-binding Methyltransferase Nucleus Reference proteome S-adenosyl-L-methionine Transferase Zinc | MLPAWGTSTE | MLPAWGTSTEATASHAGWDGDDEGDIRAAYTEDEKKENIPPISLTSVSTNGAYPGQKRRRSESVRTLKPECPPEETQRLRQRRRISATDATQSSRTMNVIEDRKPRVNRARKSQDAPSTSTCGFETPVGTKRKSKAADSQKPPKQSKLRKIDEASTSKAVDNSSKDGKKTTKPAVTQSNRRRSGLSLRPVPIETIFSESSGRESSTEDEADVSHQQRVEKIAKNPIMVVVLPLGPGNYPNNERITVVSTYKSRVNKNCNEARRAQRHGSWSRKGIAFPGIPTKKFTKSDLAKYGAHASNWPAQAAFRSEEGKILIYYEGW... | methylation negative regulation of gene expression, epigenetic heterochromatin; nuclear lamina double-stranded DNA binding histone H3K9 methyltransferase activity histone H3K9 monomethyltransferase activity histone methyltransferase activity metal ion binding Caenorhabditis elegansChromosome Metal-binding Methyltransfe... |
nematode larval development positive regulation of gastrulation positive regulation of oocyte development positive regulation of vulval development transcription elongation-coupled chromatin remodeling | euchromatin; nucleoplasm; nucleus | peptidyl-prolyl cis-trans isomerase activity RNA binding RNA polymerase II complex binding | Caenorhabditis elegans | Alternative splicing Chromosome Coiled coil Isomerase Nucleus Reference proteome RNA-binding Rotamase Transcription Transcription regulation | MAVLIETTLG | MAVLIETTLGDLIIDLFVKERPRCSLNFLKLCKKKYYNLNQFHSIERNYVAQTGDPTGTGKGGESVYSDMYGEQGRYFEREDLPKMRHTRMGIVSFVNNGDNMLGSQFFITLGENLDYLDDQHTIFGQVTEGLETLEKLNEQLADTNNRPFKDIRISHTIVLDDPFDEDARISFPPRSPSPTYEMLVKTDQIALDEKEDEDEGKTAEEIAEELQQREMAEQAQILEMVGDLKDADEVPPENVLFVCKLNPVTTDEDLEIIFSRFGKINNCEIVRDRRSGDSLQYAFIEFDNAKSCEQAFFKMDNVLIDDRRIHVDFSQSV... | nematode larval development positive regulation of gastrulation positive regulation of oocyte development positive regulation of vulval development transcription elongation-coupled chromatin remodeling euchromatin; nucleoplasm; nucleus peptidyl-prolyl cis-trans isomerase activity RNA binding RNA polymerase II complex b... |
cell fate specification embryo development ending in birth or egg hatching embryonic pattern specification negative regulation of transcription by RNA polymerase II regulation of translation | cytoplasm; cytosol; P granule | metal ion binding mRNA 3'-UTR binding poly(U) RNA binding single-stranded RNA binding transcription corepressor activity | Caenorhabditis elegans | 3D-structure Cytoplasm Developmental protein Differentiation Metal-binding Reference proteome Repeat RNA-binding Translation regulation Zinc Zinc-finger | MADNDFLSGE | MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH | cell fate specification embryo development ending in birth or egg hatching embryonic pattern specification negative regulation of transcription by RNA polymerase II regulation of translation cytoplasm; cytosol; P granule metal ion binding mRNA 3'-UTR binding poly(U) RNA binding single-stranded RNA binding transcription... |
intracellular calcium ion homeostasis ovulation positive regulation of engulfment of apoptotic cell positive regulation of smooth muscle contraction reproduction store-operated calcium entry | cytoplasm; dendrite; endoplasmic reticulum; intracellular organelle; neuronal cell body; plasma membrane | calcium channel activity calcium channel regulator activity calcium ion binding identical protein binding | Caenorhabditis elegans | 3D-structure Alternative splicing Calcium Calcium channel Calcium transport Coiled coil Ion channel Ion transport Membrane Metal-binding Reference proteome Signal Transmembrane Transmembrane helix Transport | MGRVSWIIAL | MGRVSWIIALYLTINVVIVVNGDRVTRNVEVTAEEEKIRDKLGYEAIRDIHRDMDDDHSGSIDRNESTGFMKEDMQMRGSERTRRENKFHGDDDAITVDDLWEAWFESIERTWTNERLVEWLINDVNLPSIVEAVKAKKIDGKILPRFASPNSDFLNKELGIKSSVYRQKLRLNSLDVVLFGYKDNNNRTKDILLAFLALLLTSLIFLYVRQKQKAQQKVNELSNKLTELKCMETEFEDVQKMLNDERSKRSISDGVVNHTEMENLRVQLEEAERRLEANSNGSQAPLALQPLLRRTCENEMAFLEKQRQDCFKEMKEAI... | intracellular calcium ion homeostasis ovulation positive regulation of engulfment of apoptotic cell positive regulation of smooth muscle contraction reproduction store-operated calcium entry cytoplasm; dendrite; endoplasmic reticulum; intracellular organelle; neuronal cell body; plasma membrane calcium channel activity... |
anterior/posterior pattern specification epidermal cell fate specification negative regulation of gene expression nematode male tail tip morphogenesis regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Caenorhabditis elegans | DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MTSFLCSDTE | MTSFLCSDTEIESDGGISRCKKIKNKPLMEKKRRARINKSLSQLKQILIQDEHKNSIQHSKWEKADILEMAVEYLQQLRSAQPCSLSPSTSSISTPPTPKEEIRNIKVPLNPIASFLNPMMQQYVAYQQLAQLSMYTQLFNNPAGVPLRADAGVTAQSPELAEKLKIEDRSRV | anterior/posterior pattern specification epidermal cell fate specification negative regulation of gene expression nematode male tail tip morphogenesis regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific protein dimeriz... |
chromosome condensation chromosome segregation egg-laying behavior inductive cell migration meiotic cell cycle mitotic cell cycle mitotic cytokinesis mitotic spindle midzone assembly positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic sister chromatid separation regulati... | chromosome passenger complex; condensed chromosome; cytoplasm; microtubule cytoskeleton; midbody; spindle midzone | metal ion binding | Caenorhabditis elegans | Cell cycle Cell division Chromosome Chromosome partition Cytoplasm Cytoskeleton Meiosis Metal-binding Mitosis Reference proteome Zinc | MAPGTKKKSD | MAPGTKKKSDMAKFTFYKDRLMTFKNFEYDRDPDAKCTSQAVAQAGFYCTGPQSGKCAFCNKELDFDPEDDPWYEHTKRDEPCEFVRIGKLDDSELTINDTVRLSQTAMIMTKLFEHEMMINNLSNHSSSDALFDQLKKVPNTASTTKSNSRRGK | chromosome condensation chromosome segregation egg-laying behavior inductive cell migration meiotic cell cycle mitotic cell cycle mitotic cytokinesis mitotic spindle midzone assembly positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic sister chromatid separation regulati... |
monoatomic ion transmembrane transport potassium ion transmembrane transport protein homooligomerization | axon terminus; dendrite membrane; neuronal cell body membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity voltage-gated monoatomic ion channel activity | Caenorhabditis elegans | Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MLDACSFNRF | MLDACSFNRFDSNRSSARRFSRRGSDYFGDKGISMDERIVLNVGGVRHETYQATLKKIPATRLSRLTPSLANFDPLLNEYFFDRHPAVFAMILNYYRTGKLHYPTDVCGPLFEEELQYWGLDASDTEPCCWMQLLHAKDTQETLAVLDRMDADHEDDPQLREQDTMKKFGWEEDYFQGKRTRWMKLKPQMWSLFDEPYSSQAAKLIAGISVLFIFISIFSFCLKTHQSFRLPVLIGQNITMPGGVVQPSIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVEDEPK... | monoatomic ion transmembrane transport potassium ion transmembrane transport protein homooligomerization axon terminus; dendrite membrane; neuronal cell body membrane; postsynaptic membrane; presynaptic membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity voltage-gated monoatom... |
cell fate specification defense response to Gram-positive bacterium meiotic cell cycle myoblast migration nematode larval development phosphorylation positive regulation of Ras protein signal transduction positive regulation of vulval development Ras protein signal transduction | cytoplasm | ATP binding metal ion binding mitogen-activated protein kinase kinase binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Caenorhabditis elegans | ATP-binding Kinase Magnesium Meiosis Metal-binding Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase Zinc Zinc-finger | MMQTQVASRA | MMQTQVASRAGYSNLPQFGAGIAQDIKTQAINNLKECLKLTTINRFLTSSYEEDAKSVERKIFSAVYQMTKIGLIDREKREINAIWFTFVGLSAQNIRHLEICSITDFNALFSITNQELRSLADRGRLDVETKRKLLQSTVILQNHWNAYHSRTSSGSTDEPSGQSTPAIVTPSPKFNVPSLSVTSAKMIQSSSMGFATTPKSPKTSSRLVHAIPHKWHRSTKFRFSGDAVCHFCQRPLGFGFLNAWEKCRSCKWKVHTQCKGRVGDSCGLTPDHLRFLFDKLIQENNGGMWKDPQSVPGSRSMNEPAFQFPDTAIDSSS... | cell fate specification defense response to Gram-positive bacterium meiotic cell cycle myoblast migration nematode larval development phosphorylation positive regulation of Ras protein signal transduction positive regulation of vulval development Ras protein signal transduction cytoplasm ATP binding metal ion binding m... |
cadmium ion transmembrane transport cellular detoxification of cadmium ion detoxification of cadmium ion detoxification of copper ion heme transport response to cadmium ion transmembrane transport | early endosome; late endosome; membrane; recycling endosome; vacuolar membrane | ABC-type heme transporter activity ATP binding ATP hydrolysis activity cadmium ion transmembrane transporter activity heme binding | Caenorhabditis elegans | ATP-binding Endosome Membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix Transport Vacuole | MGFSPFLDEC | MGFSPFLDECRAEGLWPIGPSCNKIISFGVYTFFIVVNFIVLCIPNSNSANNNYRRMTDDDASSTSKLTISKILSICTIFAVICQSIFYFCFTFYFHPYTHLLLAFCVSKLFFWILSLCSFSKWRNQPSTPISLAFAFSAALLIHCIPLTDWKKYFEPTSKNRGDLTFYIIELALVTVVFFFTIVTGLFNFSGCSSRESAWNNLSKKVVTVAPYIWPTKSISLQLRVVFCLFLLIIGRLINVSLPILSKWIVDELATPDTFQYSLLFLATFLKFLQGNGAMGGFLNTVRTYLWIPIQQYTTRELEVELFKHLHSLSLRWH... | cadmium ion transmembrane transport cellular detoxification of cadmium ion detoxification of cadmium ion detoxification of copper ion heme transport response to cadmium ion transmembrane transport early endosome; late endosome; membrane; recycling endosome; vacuolar membrane ABC-type heme transporter activity ATP bindi... |
cell fate specification embryo development ending in birth or egg hatching membrane protein ectodomain proteolysis nematode male tail tip morphogenesis Notch signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway regulation of axon guidance regulation of mesodermal cell fate... | basolateral plasma membrane; cytoplasmic vesicle membrane; plasma membrane | metal ion binding metalloendopeptidase activity metallopeptidase activity | Caenorhabditis elegans | Cell membrane Cleavage on pair of basic residues Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Signal Transmembrane Transmembrane helix Zinc Zymogen | MSSPIRNRLQ | MSSPIRNRLQLVVTLIFCLFFENVNGLNNFIDNFETLNYRATHVANQVTRRKRSIDSAASHYQEPIGFRFNAYNRTFHVQLHPIDDSLFHEDHMSDVDGGYADIKPSHFLYEGYLKDDPNSHVHGSVFDGVFEGHIQTGEGRRYSIDKAAKYFERDDRPTQYHSIIYRDDEINHRKWRVKRDAENLSEQMQGCGFSSRVRREMTDVQNSGESTDFFTNYMTMGGRSKRANTLRDHDGLYFVRTCSLYMQADHKLYEHIRMKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNFNGIKGLHFVIQRTSIYTPDSCDRGRA... | cell fate specification embryo development ending in birth or egg hatching membrane protein ectodomain proteolysis nematode male tail tip morphogenesis Notch signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway regulation of axon guidance regulation of mesodermal cell fate... |
fucosylation N-glycan fucosylation protein N-linked glycosylation | Golgi cisterna membrane | alpha-(1->6)-fucosyltransferase activity fucosyltransferase activity galactoside 6-L-fucosyltransferase activity glycoprotein 6-alpha-L-fucosyltransferase activity metal ion binding | Caenorhabditis elegans | Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Magnesium Manganese Membrane Metal-binding Reference proteome SH3 domain Signal-anchor Transferase Transmembrane Transmembrane helix | MLKCIAAVGT | MLKCIAAVGTVVWMTMFLFLYSQLSNNQSGGDSIRAWRQTKEAIDKLQEQNEDLKSILEKERQERNDQHKKIMEQSHQLPPNPENPSLPKPEPVKEIISKPSILGPVQQEVQKRMLDDRIREMFYLLHSQTIENSTKILLETQMISLMGLSAQLEKLEGSEEERFKQRTAITQRIFKSIEKLQNPKACSEAKTLVCNLDKECGFGCQLHHVTYCAITAFATQRMMVLKRDGSSWKYSSHGWTSVFKKLSKCSFDEAVGNTEAKPFAEPSPARVVSLGIVDSLITKPTFLPQAVPEQLLESLTSLHSHPPAFFVGTFISYL... | fucosylation N-glycan fucosylation protein N-linked glycosylation Golgi cisterna membrane alpha-(1->6)-fucosyltransferase activity fucosyltransferase activity galactoside 6-L-fucosyltransferase activity glycoprotein 6-alpha-L-fucosyltransferase activity metal ion binding Caenorhabditis elegansDisulfide bond Glycoprotei... |
mRNA processing regulation of alternative mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome RNA splicing | nucleus; P granule; ribonucleoprotein complex | mRNA binding pre-mRNA intronic binding single-stranded RNA binding | Caenorhabditis elegans | Alternative splicing mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding | MDCDNGVVSE | MDCDNGVVSEISDDKELLNLETVIPPPPNDSGHEFIGPSSGPPQVTITPSGVQSGSANGVSTSQQQQYSAEYLSQLLKDKKQLAAFPNVFHHLERLADEEINKVRVVLFQCEFSKESAPLPDAEGDSTVHTEKVFVPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEELNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAPEGEDDLKRKQLMELAIINGTYRSGTDQSALAAAQLAAVKHQQQPFAAALQAAALQRGVLPMMANGLSRSPTMAVCGAPIVMSPSGRASS... | mRNA processing regulation of alternative mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome RNA splicing nucleus; P granule; ribonucleoprotein complex mRNA binding pre-mRNA intronic binding single-stranded RNA binding Caenorhabditis elegansAlternative splicing mRNA processing mRNA splicing Nuc... |
mesodermal cell differentiation muscle cell differentiation myoblast fate specification negative regulation of transcription by RNA polymerase II neuroblast differentiation positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II r... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Caenorhabditis elegans | Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MNELLAEMAA | MNELLAEMAAVSSRRKQSKPRRMSGEGDAMMSPIDLSTKSFDENNCEKGAGGALPLEDRSNILPHFSVPFANPQQFLSLCAQLGNSSSRNVSSTASTTSSCPIQSCSQSFSSPAALTWHVLDAHEDEQEIFSCDVCTTTFSNGQDIREHKCQKTLASRSTSVPPSTIPSSVCFLSTPTTPCLQFSINESIGTSEIREEDEEEDMDVEDGEHVANQLFGHLLQKSDDKSKMASLFNHAFPPFAAFPNMPPPFLMRQPFDPRADVFAAGRHDNDDDWEALMEISTSDEAEKIRALVGDKAVPTTDPNQCILCRRVLSCKSAL... | mesodermal cell differentiation muscle cell differentiation myoblast fate specification negative regulation of transcription by RNA polymerase II neuroblast differentiation positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II r... |
cell differentiation chemotaxis dauer larval development determination of adult lifespan heat acclimation male mating behavior negative regulation of transcription by RNA polymerase II positive regulation of dauer larval development positive regulation of transcription by RNA polymerase II regulation of dauer larval de... | nucleus | (25S)-Delta(4)-dafachronate binding (25S)-Delta(7)-dafachronate binding DNA-binding transcription factor activity nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Caenorhabditis elegans | Alternative initiation Alternative splicing Developmental protein DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MGTNGGVIAE | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQMSTPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRVCGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFTVGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYPPQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLTMMHNGEKSPDGYDPNIMAHR... | cell differentiation chemotaxis dauer larval development determination of adult lifespan heat acclimation male mating behavior negative regulation of transcription by RNA polymerase II positive regulation of dauer larval development positive regulation of transcription by RNA polymerase II regulation of dauer larval de... |
cysteine biosynthetic process from serine sulfur compound biosynthetic process | cytoplasm | cystathionine beta-synthase activity cysteine synthase activity pyridoxal phosphate binding | Caenorhabditis elegans | Alternative splicing Amino-acid biosynthesis Cysteine biosynthesis Cytoplasm Lyase Pyridoxal phosphate Reference proteome | MIQNEVSATH | MIQNEVSATHGSTKKGITYNTILEAAQRPTPLVPLKKLKVEHQLQSDIYVKLEYLNIAGSLEDRTADKAFQFAEEIGVVRGDEVFVTAGGSAAISYATVAAVKGIKLTIYAPKGEFDLVDTVLHTLGVKTVELPFGTFAEARVQTDEAAQQKGVFSLNKFTTNAAFVANLQKTALEIEKAVNNKSIGKVGAVVIPLNTGAAAAGIAAYYKGIGEHGVRVVGVTCKKDTIPEMGLDLKNDLLQEYNVEKREVEEDEAYSFTRHLIGTEGIMAGPSSGAAVLEAIKLAKELPAGSTIVVVLMDGIRNYLRHFLDDDWITANK... | cysteine biosynthetic process from serine sulfur compound biosynthetic process cytoplasm cystathionine beta-synthase activity cysteine synthase activity pyridoxal phosphate binding Caenorhabditis elegansAlternative splicing Amino-acid biosynthesis Cysteine biosynthesis Cytoplasm Lyase Pyridoxal phosphate Reference prot... |
cell differentiation ecdysis, collagen and cuticulin-based cuticle molting cycle, collagen and cuticulin-based cuticle nematode larval development positive regulation of DNA-templated transcription protein autoprocessing regulation of neuron remodeling regulation of synapse assembly | apical plasma membrane; basal part of cell; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; nucleus; transcription regulator complex | DNA-binding transcription factor activity peptidase activity sequence-specific DNA binding | Caenorhabditis elegans | Activator Autocatalytic cleavage Cell membrane Cytoplasm Differentiation DNA-binding Endoplasmic reticulum Glycoprotein Hydrolase Membrane Nucleus Protease Reference proteome Transcription Transcription regulation Transmembrane Transmembrane helix | MSSSDLLKGE | MSSSDLLKGEFDGLNSEHFNMMQYLTQDTDEDDGSMVSPTSSADSMHQNLGVQQQQQQMLQAQQRQNQNGIFQPRRFPESPAMTDPCGNVSSSSSSSHHSDPMFSPNEFNGYAGANDNGNQTMNNIQSQQLSQQQHQQTRGGNLMMPQQSSIHAQMQNMNAPQFWSQPGTAAVNQPTNTLAQLNLFNIIRGGADSGMPSPVLEMPRKRSRLDTPCETPRIAPSFAGIDGFPDENYSQQQAIRFSKFQEEQWSPLYDINAQPLQQLQVHVVADKGFNYNSNDNCFVNQKKNHFQISVNVEASDTMPPKYVNFNNRLVPIRD... | cell differentiation ecdysis, collagen and cuticulin-based cuticle molting cycle, collagen and cuticulin-based cuticle nematode larval development positive regulation of DNA-templated transcription protein autoprocessing regulation of neuron remodeling regulation of synapse assembly apical plasma membrane; basal part o... |
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