Biological Process
stringlengths
7
1.01k
Cellular Component
stringlengths
6
867
Molecular Function
stringlengths
11
871
Organism
stringlengths
8
73
Keywords
stringlengths
1
810
Sequence 10
stringlengths
5
10
Sequence
stringlengths
5
1.02k
Combined
stringlengths
136
3.91k
ascospore formation transmembrane transport water transport
endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane
water channel activity
Saccharomyces cerevisiae
Cell membrane Endoplasmic reticulum Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport
MSSNDSNDTD
MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV
ascospore formation transmembrane transport water transport endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane water channel activity Saccharomyces cerevisiae Cell membrane Endoplasmic reticulum Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport MSSNDSNDTD MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV
positive regulation of interleukin-8 production positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of plant-type hypersensitive response protein secretion by the type III secretion system protein ubiquitination
extracellular region; host cell cytoplasm; host cell plasma membrane; membrane
catalytic activity ubiquitin protein ligase activity ubiquitin-protein transferase activity
Salmonella typhimurium
3D-structure Host cell membrane Host cytoplasm Host membrane Leucine-rich repeat Membrane Reference proteome Repeat Secreted Transferase Ubl conjugation Ubl conjugation pathway Virulence
MPFHIGSGCL
MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQTEALECIWTICHPPAGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDEDSQEILSVTLDDAGNYTVNCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPATTAPQTPAEYDAVWSAWRRAAPAEESRGRAAVVQKMRACLNNGNAVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPMLPSGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPMLPSGLLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPLSERTLQALREITSAPGYSGPIIRFDMAGASAPRETRALHLAAADWLVPAREGEPAPADRWHMFGQEDNADAFSLFLDRLSETENFIKDAGFKAQISSWLAQLAEDEALRANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNAEKGQYDNDLAALVATGREMFRLGKLEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTSVTSEMRFFDVSGVTVTDLQDAELQVKAAEKSEFREWILQWGPLHRVLERKAPERVNALREKQISDYEETYRMLSDTELRPSGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSYLNVQWRRN
positive regulation of interleukin-8 production positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of plant-type hypersensitive response protein secretion by the type III secretion system protein ubiquitination extracellular region; host cell cytoplasm; host cell plasma membrane; membrane catalytic activity ubiquitin protein ligase activity ubiquitin-protein transferase activity Salmonella typhimurium 3D-structure Host cell membrane Host cytoplasm Host membrane Leucine-rich repeat Membrane Reference proteome Repeat Secreted Transferase Ubl conjugation Ubl conjugation pathway Virulence MPFHIGSGCL MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQTEALECIWTICHPPAGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDEDSQEILSVTLDDAGNYTVNCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPATTAPQTPAEYDAVWSAWRRAAPAEESRGRAAVVQKMRACLNNGNAVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPMLPSGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPMLPSGLLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPLSERTLQALREITSAPGYSGPIIRFDMAGASAPRETRALHLAAADWLVPAREGEPAPADRWHMFGQEDNADAFSLFLDRLSETENFIKDAGFKAQISSWLAQLAEDEALRANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNAEKGQYDNDLAALVATGREMFRLGKLEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTSVTSEMRFFDVSGVTVTDLQDAELQVKAAEKSEFREWILQWGPLHRVLERKAPERVNALREKQISDYEETYRMLSDTELRPSGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSYLNVQWRRN
ERK1 and ERK2 cascade gene expression insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway negative regulation of glucose import negative regulation of glycogen biosynthetic process negative regulation of insulin receptor signaling pathway negative regulation of phosphorylation negative regulation of Wnt signaling pathway positive regulation of cold-induced thermogenesis positive regulation of phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway response to insulin vascular associated smooth muscle cell migration
cytoplasm; protein-containing complex
insulin receptor binding protein-macromolecule adaptor activity signaling receptor complex adaptor activity
Rattus norvegicus
Cytoplasm Phosphoprotein Reference proteome SH2 domain
MNNDINSSVE
MNNDINSSVESLNSACNMQSDTDTVPLLENGQSASNQPSASSSRGQPQASPRQKMQRSQPVHIQPLRRLQEEDQQLRTSSLPAIPNPFPELAGGAPGSPPSVAPSSLPPPPSQPPAKHFPPGFQLAKLTRPGLWTKTTARFSKRQPKNQCQTDTANAVSRIPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVTWCQQSNGGQAQLLQNFLNSSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKIEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQQRKGLAPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNSVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHQQKIRNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL
ERK1 and ERK2 cascade gene expression insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway negative regulation of glucose import negative regulation of glycogen biosynthetic process negative regulation of insulin receptor signaling pathway negative regulation of phosphorylation negative regulation of Wnt signaling pathway positive regulation of cold-induced thermogenesis positive regulation of phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway response to insulin vascular associated smooth muscle cell migration cytoplasm; protein-containing complex insulin receptor binding protein-macromolecule adaptor activity signaling receptor complex adaptor activity Rattus norvegicus Cytoplasm Phosphoprotein Reference proteome SH2 domain MNNDINSSVE MNNDINSSVESLNSACNMQSDTDTVPLLENGQSASNQPSASSSRGQPQASPRQKMQRSQPVHIQPLRRLQEEDQQLRTSSLPAIPNPFPELAGGAPGSPPSVAPSSLPPPPSQPPAKHFPPGFQLAKLTRPGLWTKTTARFSKRQPKNQCQTDTANAVSRIPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVTWCQQSNGGQAQLLQNFLNSSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKIEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQQRKGLAPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNSVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHQQKIRNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL
insulin processing insulin secretion intracellular zinc ion homeostasis positive regulation of insulin secretion regulation of vesicle-mediated transport response to glucose response to interleukin-1 response to type II interferon response to zinc ion zinc ion import across plasma membrane zinc ion import into organelle zinc ion transmembrane transport zinc ion transport
cytoplasmic vesicle; plasma membrane; secretory granule; secretory granule membrane; transport vesicle membrane
metal ion binding protein homodimerization activity zinc ion transmembrane transporter activity zinc:proton antiporter activity
Rattus norvegicus
Antiport Cell membrane Cytoplasmic vesicle Ion transport Membrane Metal-binding Reference proteome Transmembrane Transmembrane helix Transport Zinc Zinc transport
MEFLERTYLV
MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSVLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD
insulin processing insulin secretion intracellular zinc ion homeostasis positive regulation of insulin secretion regulation of vesicle-mediated transport response to glucose response to interleukin-1 response to type II interferon response to zinc ion zinc ion import across plasma membrane zinc ion import into organelle zinc ion transmembrane transport zinc ion transport cytoplasmic vesicle; plasma membrane; secretory granule; secretory granule membrane; transport vesicle membrane metal ion binding protein homodimerization activity zinc ion transmembrane transporter activity zinc:proton antiporter activity Rattus norvegicus Antiport Cell membrane Cytoplasmic vesicle Ion transport Membrane Metal-binding Reference proteome Transmembrane Transmembrane helix Transport Zinc Zinc transport MEFLERTYLV MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSSKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLTLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSVLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVATAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD
response to antibiotic translational elongation
cytoplasm; guanyl-nucleotide exchange factor complex; plasma membrane
GTP binding GTPase activity guanosine tetraphosphate binding RNA binding translation elongation factor activity
Escherichia coli
3D-structure Acetylation Antibiotic resistance Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Elongation factor GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding
MSKEKFERTK
MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
response to antibiotic translational elongation cytoplasm; guanyl-nucleotide exchange factor complex; plasma membrane GTP binding GTPase activity guanosine tetraphosphate binding RNA binding translation elongation factor activity Escherichia coli 3D-structure Acetylation Antibiotic resistance Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Elongation factor GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding MSKEKFERTK MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
response to antibiotic translational elongation
cytoplasm; guanyl-nucleotide exchange factor complex; plasma membrane
GTP binding GTPase activity guanosine tetraphosphate binding RNA binding translation elongation factor activity
Escherichia coli
3D-structure Acetylation Antibiotic resistance Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Elongation factor GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding
MSKEKFERTK
MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS
response to antibiotic translational elongation cytoplasm; guanyl-nucleotide exchange factor complex; plasma membrane GTP binding GTPase activity guanosine tetraphosphate binding RNA binding translation elongation factor activity Escherichia coli 3D-structure Acetylation Antibiotic resistance Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Elongation factor GTP-binding Membrane Methylation Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome RNA-binding MSKEKFERTK MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles reclusa
Cytolysis Dermonecrotic toxin Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen
MLLYVTLILG
MLLYVTLILGCWSAFSESAETDVAERANKRPIWIMGHMVNAIYQIDEFVNLGANSIETDVSFDKDANPEYTYHGVPCDCGRSCLKWEYFSDFLKGLRKATTPGDSKYHAKLVLVVFDLKTGSLYDNQAYDAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYKLITGFKETLKSEGHPELMDKVGHDFSGNDAIGDVGNAYKKAGVTGHVWQSDGITNCLLRGLSRVKEAVKNRDSSNGFINKVYYWTVDKRATTREALDAGVDGVMTNYPDVITDVLNESAYKAKFRIATYDDNPWETFKN
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles reclusa Cytolysis Dermonecrotic toxin Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen MLLYVTLILG MLLYVTLILGCWSAFSESAETDVAERANKRPIWIMGHMVNAIYQIDEFVNLGANSIETDVSFDKDANPEYTYHGVPCDCGRSCLKWEYFSDFLKGLRKATTPGDSKYHAKLVLVVFDLKTGSLYDNQAYDAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYKLITGFKETLKSEGHPELMDKVGHDFSGNDAIGDVGNAYKKAGVTGHVWQSDGITNCLLRGLSRVKEAVKNRDSSNGFINKVYYWTVDKRATTREALDAGVDGVMTNYPDVITDVLNESAYKAKFRIATYDDNPWETFKN
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles intermedia
3D-structure Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen
MLPYIVLVLG
MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDENPWVTFKK
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles intermedia 3D-structure Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen MLPYIVLVLG MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDENPWVTFKK
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles intermedia
Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen
MLPYIVLVLG
MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMEKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles intermedia Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen MLPYIVLVLG MLPYIVLVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMEKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles intermedia
3D-structure Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen
ARVVLGCWSV
ARVVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles intermedia 3D-structure Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen ARVVLGCWSV ARVVLGCWSVLSQAAQTDDEERAGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles intermedia
Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen
MLPYIALILV
MLPYIALILVCWSVLSQAAQTDVEGRADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQATANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles intermedia Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Signal Toxin Zymogen MLPYIALILV MLPYIALILVCWSVLSQAAQTDVEGRADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQATANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
killing of cells of another organism lipid catabolic process
extracellular region
lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity
Loxosceles intermedia
Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Toxin Zymogen
DVEERADKRR
DVEERADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQAIANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
killing of cells of another organism lipid catabolic process extracellular region lyase activity metal ion binding phosphoric diester hydrolase activity toxin activity Loxosceles intermedia Cytolysis Dermonecrotic toxin Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Lipid degradation Lipid metabolism Lyase Magnesium Metal-binding Secreted Toxin Zymogen DVEERADKRR DVEERADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQAIANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
camera-type eye development caudate nucleus development cerebellar Purkinje cell differentiation cerebellum development cerebral cortex development epithelial cell proliferation involved in lung morphogenesis forebrain development gene expression innate vocalization behavior lung alveolus development lung development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation involved in lung morphogenesis positive regulation of mesenchymal cell proliferation post-embryonic development putamen development regulation of transcription by RNA polymerase II response to testosterone righting reflex skeletal muscle tissue development smooth muscle tissue development vocal learning vocalization behavior
nucleus
DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding metal ion binding nuclear androgen receptor binding protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription coregulator binding
Rattus norvegicus
Coiled coil DNA-binding Metal-binding Nucleus Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger
MMQESATETI
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQCQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSQEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
camera-type eye development caudate nucleus development cerebellar Purkinje cell differentiation cerebellum development cerebral cortex development epithelial cell proliferation involved in lung morphogenesis forebrain development gene expression innate vocalization behavior lung alveolus development lung development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation involved in lung morphogenesis positive regulation of mesenchymal cell proliferation post-embryonic development putamen development regulation of transcription by RNA polymerase II response to testosterone righting reflex skeletal muscle tissue development smooth muscle tissue development vocal learning vocalization behavior nucleus DNA binding DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding metal ion binding nuclear androgen receptor binding protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription coregulator binding Rattus norvegicus Coiled coil DNA-binding Metal-binding Nucleus Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger MMQESATETI MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQCQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSQEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
midbrain development regulation of transcription by RNA polymerase II
nucleus
2-oxoglutarate-dependent dioxygenase activity histone demethylase activity histone H3K27me2/H3K27me3 demethylase activity histone H3K36 demethylase activity histone H3K9 demethylase activity histone H4K20 demethylase activity metal ion binding transcription coregulator activity
Danio rerio
Chromatin regulator Dioxygenase Iron Metal-binding Neurogenesis Nucleus Oxidoreductase Reference proteome Transcription Transcription regulation Zinc Zinc-finger
MATAQLYCVC
MATAQLYCVCRQPYDVSRFMIECDICKDWFHGSCVEVEEHYAVDIDVYHCPNCDVHHGPSLMKKRRNWHRHDYTEPDDGSKPVQAGTSVFVRELQARTFPSGDEILQPMHGGQVTQRYLERHGFRYPIIVSKREELGLRLPPPDFSIKDVERYVGGNKVIDVIDVARQADSKMKLKAFVKYYYSPQRPKVLNVISLEFSDTKMAELVVVPDIAQKMSWVENYWPDDSYFPKPFVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTPANLALYEEWSSSPNQSEVFFGEKVDKCYKCVVRQGTTLLIPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMERRLKTPDLFKFPYFEAICWYVAKNLLETLKESREENCLPPEYLIKGVKALITALRNWLKREVTEPASEVPDHIRPNHLIKMLTKEIQYLENGNCGNKPMKLQESSICPSTRSAHERGSHARKTARRLRGHHHHHHRHHHHHHHHHHHNHQHSDGPKAPSHLDIYEQHTQEVLKRLEMGPYEEDASFNLKVNGKFNKVSTASAAAAERSLENDLRLVLCNGQIVR
midbrain development regulation of transcription by RNA polymerase II nucleus 2-oxoglutarate-dependent dioxygenase activity histone demethylase activity histone H3K27me2/H3K27me3 demethylase activity histone H3K36 demethylase activity histone H3K9 demethylase activity histone H4K20 demethylase activity metal ion binding transcription coregulator activity Danio rerio Chromatin regulator Dioxygenase Iron Metal-binding Neurogenesis Nucleus Oxidoreductase Reference proteome Transcription Transcription regulation Zinc Zinc-finger MATAQLYCVC MATAQLYCVCRQPYDVSRFMIECDICKDWFHGSCVEVEEHYAVDIDVYHCPNCDVHHGPSLMKKRRNWHRHDYTEPDDGSKPVQAGTSVFVRELQARTFPSGDEILQPMHGGQVTQRYLERHGFRYPIIVSKREELGLRLPPPDFSIKDVERYVGGNKVIDVIDVARQADSKMKLKAFVKYYYSPQRPKVLNVISLEFSDTKMAELVVVPDIAQKMSWVENYWPDDSYFPKPFVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTPANLALYEEWSSSPNQSEVFFGEKVDKCYKCVVRQGTTLLIPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMERRLKTPDLFKFPYFEAICWYVAKNLLETLKESREENCLPPEYLIKGVKALITALRNWLKREVTEPASEVPDHIRPNHLIKMLTKEIQYLENGNCGNKPMKLQESSICPSTRSAHERGSHARKTARRLRGHHHHHHRHHHHHHHHHHHNHQHSDGPKAPSHLDIYEQHTQEVLKRLEMGPYEEDASFNLKVNGKFNKVSTASAAAAERSLENDLRLVLCNGQIVR
gamma-tubulin complex localization microtubule nucleation by interphase microtubule organizing center microtubule nucleation by spindle pole body mitotic spindle assembly
cytoplasm; equatorial microtubule organizing center; gamma-tubulin complex; gamma-tubulin ring complex; gamma-tubulin small complex; inner plaque of mitotic spindle pole body; interphase microtubule organizing center; mitotic spindle pole body; nucleus; spindle
spindle pole body anchor activity
Schizosaccharomyces pombe
3D-structure Cytoplasm Cytoskeleton Reference proteome
MSESTKETIE
MSESTKETIEVLYEIGTLLGTELDKTTLSLCISLCENNVHPEAIAQIIREIRMAQEQTVDTEPS
gamma-tubulin complex localization microtubule nucleation by interphase microtubule organizing center microtubule nucleation by spindle pole body mitotic spindle assembly cytoplasm; equatorial microtubule organizing center; gamma-tubulin complex; gamma-tubulin ring complex; gamma-tubulin small complex; inner plaque of mitotic spindle pole body; interphase microtubule organizing center; mitotic spindle pole body; nucleus; spindle spindle pole body anchor activity Schizosaccharomyces pombe 3D-structure Cytoplasm Cytoskeleton Reference proteome MSESTKETIE MSESTKETIEVLYEIGTLLGTELDKTTLSLCISLCENNVHPEAIAQIIREIRMAQEQTVDTEPS
killing of cells of another organism proteolysis
extracellular region
serine-type endopeptidase activity toxin activity
Bothrops alternatus
Blood coagulation cascade activating toxin Cytolysis Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Hemostasis impairing toxin Hydrolase Myotoxin Protease Secreted Serine protease Signal Toxin Zymogen
MVLIRVLANL
MVLIRVLANLLILQLSYAQKASELVIGGDECNINEHRSLVVLFNSSGFLCAGTLINQEWVLTAANCDRKNIRIKLGMHSKNVTNEDEQTRVPKRSTFVSVAKTSHQTLGTRTSMLIRLKRPVNDSPHIAPLSLPSSPPSVGSVCRVMGWGTISPTKVSYPDVPHCANINLLDYEVCREAHGGLPATSRTLCAGILEGGKDSCQGDSGGPLICNGQFQGILSWGVHPCGQPHKPGVYTKVSDYSEWIQSIIAGNTDVTCPP
killing of cells of another organism proteolysis extracellular region serine-type endopeptidase activity toxin activity Bothrops alternatus Blood coagulation cascade activating toxin Cytolysis Direct protein sequencing Disulfide bond Glycoprotein Hemolysis Hemostasis impairing toxin Hydrolase Myotoxin Protease Secreted Serine protease Signal Toxin Zymogen MVLIRVLANL MVLIRVLANLLILQLSYAQKASELVIGGDECNINEHRSLVVLFNSSGFLCAGTLINQEWVLTAANCDRKNIRIKLGMHSKNVTNEDEQTRVPKRSTFVSVAKTSHQTLGTRTSMLIRLKRPVNDSPHIAPLSLPSSPPSVGSVCRVMGWGTISPTKVSYPDVPHCANINLLDYEVCREAHGGLPATSRTLCAGILEGGKDSCQGDSGGPLICNGQFQGILSWGVHPCGQPHKPGVYTKVSDYSEWIQSIIAGNTDVTCPP
adaptive immune response B cell receptor signaling pathway immune response immunoglobulin mediated immune response
blood microparticle; extracellular exosome; extracellular region; extracellular space; IgA immunoglobulin complex; IgD immunoglobulin complex; IgE immunoglobulin complex; IgG immunoglobulin complex; IgM immunoglobulin complex; plasma membrane
antigen binding
Homo sapiens
3D-structure Adaptive immunity Bence-Jones protein Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Reference proteome Secreted
GQPKANPTVT
GQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
adaptive immune response B cell receptor signaling pathway immune response immunoglobulin mediated immune response blood microparticle; extracellular exosome; extracellular region; extracellular space; IgA immunoglobulin complex; IgD immunoglobulin complex; IgE immunoglobulin complex; IgG immunoglobulin complex; IgM immunoglobulin complex; plasma membrane antigen binding Homo sapiens 3D-structure Adaptive immunity Bence-Jones protein Cell membrane Direct protein sequencing Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Reference proteome Secreted GQPKANPTVT GQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
glutathione metabolic process
cytoplasm; cytosol; extracellular exosome
glutathione transferase activity
Homo sapiens
3D-structure Cytoplasm Direct protein sequencing Reference proteome Transferase
MGLELFLDLV
MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
glutathione metabolic process cytoplasm; cytosol; extracellular exosome glutathione transferase activity Homo sapiens 3D-structure Cytoplasm Direct protein sequencing Reference proteome Transferase MGLELFLDLV MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
anterior/posterior pattern specification blood vessel development determination of left/right symmetry gastrulation heart development nodal signaling pathway
cell surface; extracellular region; plasma membrane; side of membrane
activin receptor binding nodal binding
Homo sapiens
Cell membrane Developmental protein Disease variant Disulfide bond EGF-like domain Gastrulation Glycoprotein GPI-anchor Heterotaxy Lipoprotein Membrane Reference proteome Secreted Signal
MTWRHHVRLL
MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
anterior/posterior pattern specification blood vessel development determination of left/right symmetry gastrulation heart development nodal signaling pathway cell surface; extracellular region; plasma membrane; side of membrane activin receptor binding nodal binding Homo sapiens Cell membrane Developmental protein Disease variant Disulfide bond EGF-like domain Gastrulation Glycoprotein GPI-anchor Heterotaxy Lipoprotein Membrane Reference proteome Secreted Signal MTWRHHVRLL MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development
cytosol; endocytic vesicle membrane; endoplasmic reticulum membrane; endosome membrane; extracellular exosome; extracellular space; mitochondrial outer membrane; mitochondrion; neuron projection; neuronal cell body; nucleoplasm; nucleus; plasma membrane; vesicle
protein tag activity ubiquitin protein ligase binding
Homo sapiens
3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC
energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development cytosol; endocytic vesicle membrane; endoplasmic reticulum membrane; endosome membrane; extracellular exosome; extracellular space; mitochondrial outer membrane; mitochondrion; neuron projection; neuronal cell body; nucleoplasm; nucleus; plasma membrane; vesicle protein tag activity ubiquitin protein ligase binding Homo sapiens 3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC
modification-dependent protein catabolic process protein ubiquitination
cytosol; endocytic vesicle membrane; endoplasmic reticulum membrane; endosome membrane; extracellular exosome; extracellular space; mitochondrial outer membrane; nucleoplasm; nucleus; plasma membrane; vesicle
protease binding protein tag activity RNA binding ubiquitin protein ligase binding
Homo sapiens
3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV
modification-dependent protein catabolic process protein ubiquitination cytosol; endocytic vesicle membrane; endoplasmic reticulum membrane; endosome membrane; extracellular exosome; extracellular space; mitochondrial outer membrane; nucleoplasm; nucleus; plasma membrane; vesicle protease binding protein tag activity RNA binding ubiquitin protein ligase binding Homo sapiens 3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV
adipose tissue development energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male gonad development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development
cytosol; cytosolic small ribosomal subunit; mitochondrial outer membrane; mitochondrion; myelin sheath; neuron projection; neuronal cell body; nucleoplasm
protein tag activity structural constituent of ribosome ubiquitin protein ligase binding
Mus musculus
ADP-ribosylation Cytoplasm Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY
adipose tissue development energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male gonad development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development cytosol; cytosolic small ribosomal subunit; mitochondrial outer membrane; mitochondrion; myelin sheath; neuron projection; neuronal cell body; nucleoplasm protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Mus musculus ADP-ribosylation Cytoplasm Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY
adipose tissue development energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male gonad development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development
mitochondrial outer membrane; mitochondrion; neuron projection; neuronal cell body; nucleus
protein tag activity ubiquitin protein ligase binding
Rattus norvegicus
ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY
adipose tissue development energy homeostasis fat pad development female gonad development female meiosis I hypothalamus gonadotrophin-releasing hormone neuron development male gonad development male meiosis I mitochondrion transport along microtubule modification-dependent protein catabolic process neuron projection morphogenesis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of protein monoubiquitination positive regulation of protein ubiquitination protein ubiquitination regulation of mitochondrial membrane potential regulation of neuron apoptotic process regulation of proteasomal protein catabolic process seminiferous tubule development mitochondrial outer membrane; mitochondrion; neuron projection; neuronal cell body; nucleus protein tag activity ubiquitin protein ligase binding Rattus norvegicus ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY
modification-dependent protein catabolic process protein ubiquitination
cytosolic small ribosomal subunit; mitochondrial outer membrane; nucleus
protein tag activity structural constituent of ribosome ubiquitin protein ligase binding
Bos taurus
3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC
modification-dependent protein catabolic process protein ubiquitination cytosolic small ribosomal subunit; mitochondrial outer membrane; nucleus protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Bos taurus 3D-structure ADP-ribosylation Cytoplasm Direct protein sequencing Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC
arachidonic acid secretion lipid catabolic process phospholipid metabolic process
extracellular region
calcium ion binding ion channel regulator activity phospholipase A2 activity toxin activity
Crotalus durissus terrificus
3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Ion channel impairing toxin Metal-binding Pharmaceutical Secreted Toxin
HLLQFNKMIK
HLLQFNKMIKFETRKNAVPFYAFYGCYCGWGGQGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKNGYMFYPDSRCRGPSETC
arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding ion channel regulator activity phospholipase A2 activity toxin activity Crotalus durissus terrificus 3D-structure Blood coagulation cascade inhibiting toxin Calcium Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Ion channel impairing toxin Metal-binding Pharmaceutical Secreted Toxin HLLQFNKMIK HLLQFNKMIKFETRKNAVPFYAFYGCYCGWGGQGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKNGYMFYPDSRCRGPSETC
arachidonic acid secretion lipid catabolic process phospholipid metabolic process
extracellular region
calcium ion binding phospholipase A2 activity
Oxyuranus scutellatus scutellatus
3D-structure Direct protein sequencing Disulfide bond Secreted
NLVQFGFMIE
NLVQFGFMIECAIRNRRPALDFMNYGCYCGTVGRGTPVDDLDRCCQVHDECYATAEKHGCYPSLTTYQWECRQVGNECNSKTQCEVFVCACDLAAAKCLAQEDYNPAHFNINTGERCK
arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity Oxyuranus scutellatus scutellatus 3D-structure Direct protein sequencing Disulfide bond Secreted NLVQFGFMIE NLVQFGFMIECAIRNRRPALDFMNYGCYCGTVGRGTPVDDLDRCCQVHDECYATAEKHGCYPSLTTYQWECRQVGNECNSKTQCEVFVCACDLAAAKCLAQEDYNPAHFNINTGERCK
modification-dependent protein catabolic process protein ubiquitination
cytosol; nucleus
protein tag activity ubiquitin protein ligase binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Repeat Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN
modification-dependent protein catabolic process protein ubiquitination cytosol; nucleus protein tag activity ubiquitin protein ligase binding Saccharomyces cerevisiae 3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Repeat Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN
cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal large subunit assembly ribosomal large subunit export from nucleus ribosome biogenesis
cytoplasm; cytosol; cytosolic large ribosomal subunit; nucleus
protein tag activity structural constituent of ribosome ubiquitin protein ligase binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal large subunit assembly ribosomal large subunit export from nucleus ribosome biogenesis cytoplasm; cytosol; cytosolic large ribosomal subunit; nucleus protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Saccharomyces cerevisiae 3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal large subunit assembly ribosomal large subunit export from nucleus ribosome biogenesis
cytosol; cytosolic large ribosomal subunit; mitochondrion; nucleus
protein tag activity structural constituent of ribosome ubiquitin protein ligase binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MQIFVKTLTG
MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
cytoplasmic translation modification-dependent protein catabolic process protein ubiquitination ribosomal large subunit assembly ribosomal large subunit export from nucleus ribosome biogenesis cytosol; cytosolic large ribosomal subunit; mitochondrion; nucleus protein tag activity structural constituent of ribosome ubiquitin protein ligase binding Saccharomyces cerevisiae 3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MQIFVKTLTG MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
anterior commissure morphogenesis cerebral cortex radially oriented cell migration cerebral cortex tangential migration corticospinal tract morphogenesis DNA damage response innervation neuron migration proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination protein ubiquitination regulation of synaptic vesicle exocytosis synapse assembly involved in innervation ubiquitin-dependent protein catabolic process
cell projection; extracellular region; glutamatergic synapse; nucleus; postsynaptic cytosol; postsynaptic density; postsynaptic membrane; presynapse; presynaptic cytosol; presynaptic membrane; SCF ubiquitin ligase complex; synapse
ubiquitin ligase-substrate adaptor activity
Rattus norvegicus
Cell membrane Cell projection Developmental protein Membrane Neurogenesis Nucleus Postsynaptic cell membrane Reference proteome Secreted Synapse Ubl conjugation pathway
LASRALVCKH
LASRALVCKHWYRCLHGDENSEVWRSLCARSLEEAMRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG
anterior commissure morphogenesis cerebral cortex radially oriented cell migration cerebral cortex tangential migration corticospinal tract morphogenesis DNA damage response innervation neuron migration proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination protein ubiquitination regulation of synaptic vesicle exocytosis synapse assembly involved in innervation ubiquitin-dependent protein catabolic process cell projection; extracellular region; glutamatergic synapse; nucleus; postsynaptic cytosol; postsynaptic density; postsynaptic membrane; presynapse; presynaptic cytosol; presynaptic membrane; SCF ubiquitin ligase complex; synapse ubiquitin ligase-substrate adaptor activity Rattus norvegicus Cell membrane Cell projection Developmental protein Membrane Neurogenesis Nucleus Postsynaptic cell membrane Reference proteome Secreted Synapse Ubl conjugation pathway LASRALVCKH LASRALVCKHWYRCLHGDENSEVWRSLCARSLEEAMRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG
developmental growth root hair elongation
cytoskeleton; cytosol; endoplasmic reticulum; plant-type cell wall; plasma membrane; plasmodesma
ATP binding hydrolase activity structural constituent of cytoskeleton
Arabidopsis thaliana
Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Reference proteome
MADGEDIQPL
MADGEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDALMKILTERGYSFTTTAEREIVRDIKEKLCYIALDYEQELETAKTSSSVEKNYELPDGQVITIGSERFRCPEVLYQPSMIGMENAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF
developmental growth root hair elongation cytoskeleton; cytosol; endoplasmic reticulum; plant-type cell wall; plasma membrane; plasmodesma ATP binding hydrolase activity structural constituent of cytoskeleton Arabidopsis thaliana Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Reference proteome MADGEDIQPL MADGEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDALMKILTERGYSFTTTAEREIVRDIKEKLCYIALDYEQELETAKTSSSVEKNYELPDGQVITIGSERFRCPEVLYQPSMIGMENAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF
photosynthesis, light harvesting response to fructose
apoplast; chloroplast thylakoid membrane; nucleus; photosystem I; photosystem II; thylakoid
chlorophyll binding metal ion binding mRNA binding
Arabidopsis thaliana
3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Photosystem II Plastid Reference proteome Thylakoid Transit peptide Transmembrane Transmembrane helix
MAASTMALSS
MAASTMALSSPAFAGKAVNLSPAASEVLGSGRVTMRKTVAKPKGPSGSPWYGSDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFARNRELEVIHSRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSDGGLDYLGNPSLVHAQSILAIWATQVILMGAVEGYRVAGNGPLGEAEDLLYPGGSFDPLGLATDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLADHLADPVNNNAWAFATNFVPGK
photosynthesis, light harvesting response to fructose apoplast; chloroplast thylakoid membrane; nucleus; photosystem I; photosystem II; thylakoid chlorophyll binding metal ion binding mRNA binding Arabidopsis thaliana 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Photosystem II Plastid Reference proteome Thylakoid Transit peptide Transmembrane Transmembrane helix MAASTMALSS MAASTMALSSPAFAGKAVNLSPAASEVLGSGRVTMRKTVAKPKGPSGSPWYGSDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFARNRELEVIHSRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSDGGLDYLGNPSLVHAQSILAIWATQVILMGAVEGYRVAGNGPLGEAEDLLYPGGSFDPLGLATDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLADHLADPVNNNAWAFATNFVPGK
negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II neurogenesis Notch signaling pathway nuclear export
cytoplasm; nucleus
tubulin binding
Xenopus laevis
Cytoplasm Neurogenesis Notch signaling pathway Nucleus Reference proteome
MPDNLYATNM
MPDNLYATNMSLDLSITGHSTALPQRKSRSTYRFKAANSYVDESLFGSSGVRVDQTLQWNTAPPSQTPLLWSPGEIKENKKTSSCRPKSTPAGTPRKKIQYRVKSRTPSYCDESLFGGKVEECTWDAPWVKKEDTVKIRPLLWSPSPRLVQQSSMQNAKQGPLRAVHPPETSDSPLGTHKGLGAFWKPPESDSDYSPSPFSARQRQSTPGRETVRSASCSGRVTARRGSVKMQERPPWK
negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II neurogenesis Notch signaling pathway nuclear export cytoplasm; nucleus tubulin binding Xenopus laevis Cytoplasm Neurogenesis Notch signaling pathway Nucleus Reference proteome MPDNLYATNM MPDNLYATNMSLDLSITGHSTALPQRKSRSTYRFKAANSYVDESLFGSSGVRVDQTLQWNTAPPSQTPLLWSPGEIKENKKTSSCRPKSTPAGTPRKKIQYRVKSRTPSYCDESLFGGKVEECTWDAPWVKKEDTVKIRPLLWSPSPRLVQQSSMQNAKQGPLRAVHPPETSDSPLGTHKGLGAFWKPPESDSDYSPSPFSARQRQSTPGRETVRSASCSGRVTARRGSVKMQERPPWK
proteolysis transport of virus in host, cell to cell
host cell plasmodesma
cysteine-type endopeptidase activity serine-type peptidase activity
Tobacco etch virus
Host cell junction Host-virus interaction Hydrolase Protease Ribosomal frameshifting Serine protease Suppressor of RNA silencing Transport Viral movement protein
MALIFGTVNA
MALIFGTVNANILKEVFGGARMACVTSAHMAGANGSILKKAEETSRAIMHKPVIFGEDYITEADLPYTPLHLEVDAEMERMYYLGRRALTHGKRRKVSVNNKRNRRRKVAKTYVGRDSIVEKIVVPHTERKVDTTAAVEDICNEATTQLVHNSMPKRKKQKNFLPATSLSNVYAQTWSIVRKRHMQVEIISKKSVRARVKRFEGSVQLFASVRHMYGERKRVDLRIDNWQQETLLDLAKRFKNERVDQSKLTFGSSGLVLRQGSYGPAHWYRHGMFIVRGRSDGMLVDARAKVTFAVCHSMTHYSDKSISEAFFIPYSKKFLELRPDGISHECTRGVSVERCGEVAAILTQALSPCGKITCKRCMVETPDIVEGESGESVTNQGKLLAMLKEQYPDFPMAEKLLTRFLQQKSLVNTNLTACVSVKQLIGDRKQAPFTHVLAVSEILFKGNKLTGADLEEASTHMLEIARFLNNRTENMRIGHLGSFRNKISSKAHVNNALMCDNQLDQNGNFIWGLRGAHAKRFLKGFFTEIDPNEGYDKYVIRKHIRGSRKLAIGNLIMSTDFQTLRQQIQGETIERKEIGNHCISMRNGNYVYPCCCVTLEDGKAQYSDLKHPTKRHLVIGNSGDSKYLDLPVLNEEKMYIANEGYCYMNIFFALLVNVKEEDAKDFTKFIRDTIVPKLGAWPTMQDVATACYLLSILYPDVLRAELPRILVDHDNKTMHVLDSYGSRTTGYHMLKMNTTSQLIEFVHSGLESEMKTYNVGGMNRDVVTQGAIEMLIKSIYKPHLMKQLLEEEPYIIVLAIVSPSILIAMYNSGTFEQALQMWLPNTMRLANLAAILSALAQKLTLADLFVQQRNLINEYAQVILDNLIDGVRVNHSLSLAMEIVTIKLATQEMDMALREGGYAVTSEKVHEMLEKKLCKGFEGCMGRINLVGKILRNQAFKKALEIWAKAFNHEKHRRLRRTYRLVCEIAFQVPLGTPEGNHLKSRKWWRKKGKSSEECHDKRGFSQNLQHAS
proteolysis transport of virus in host, cell to cell host cell plasmodesma cysteine-type endopeptidase activity serine-type peptidase activity Tobacco etch virus Host cell junction Host-virus interaction Hydrolase Protease Ribosomal frameshifting Serine protease Suppressor of RNA silencing Transport Viral movement protein MALIFGTVNA MALIFGTVNANILKEVFGGARMACVTSAHMAGANGSILKKAEETSRAIMHKPVIFGEDYITEADLPYTPLHLEVDAEMERMYYLGRRALTHGKRRKVSVNNKRNRRRKVAKTYVGRDSIVEKIVVPHTERKVDTTAAVEDICNEATTQLVHNSMPKRKKQKNFLPATSLSNVYAQTWSIVRKRHMQVEIISKKSVRARVKRFEGSVQLFASVRHMYGERKRVDLRIDNWQQETLLDLAKRFKNERVDQSKLTFGSSGLVLRQGSYGPAHWYRHGMFIVRGRSDGMLVDARAKVTFAVCHSMTHYSDKSISEAFFIPYSKKFLELRPDGISHECTRGVSVERCGEVAAILTQALSPCGKITCKRCMVETPDIVEGESGESVTNQGKLLAMLKEQYPDFPMAEKLLTRFLQQKSLVNTNLTACVSVKQLIGDRKQAPFTHVLAVSEILFKGNKLTGADLEEASTHMLEIARFLNNRTENMRIGHLGSFRNKISSKAHVNNALMCDNQLDQNGNFIWGLRGAHAKRFLKGFFTEIDPNEGYDKYVIRKHIRGSRKLAIGNLIMSTDFQTLRQQIQGETIERKEIGNHCISMRNGNYVYPCCCVTLEDGKAQYSDLKHPTKRHLVIGNSGDSKYLDLPVLNEEKMYIANEGYCYMNIFFALLVNVKEEDAKDFTKFIRDTIVPKLGAWPTMQDVATACYLLSILYPDVLRAELPRILVDHDNKTMHVLDSYGSRTTGYHMLKMNTTSQLIEFVHSGLESEMKTYNVGGMNRDVVTQGAIEMLIKSIYKPHLMKQLLEEEPYIIVLAIVSPSILIAMYNSGTFEQALQMWLPNTMRLANLAAILSALAQKLTLADLFVQQRNLINEYAQVILDNLIDGVRVNHSLSLAMEIVTIKLATQEMDMALREGGYAVTSEKVHEMLEKKLCKGFEGCMGRINLVGKILRNQAFKKALEIWAKAFNHEKHRRLRRTYRLVCEIAFQVPLGTPEGNHLKSRKWWRKKGKSSEECHDKRGFSQNLQHAS
adherens junction assembly cellular response to estradiol stimulus mammary gland epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of homotypic cell-cell adhesion positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial to mesenchymal transition positive regulation of mammary gland epithelial cell proliferation regulation of canonical Wnt signaling pathway regulation of cell cycle regulation of DNA-templated transcription regulation of transforming growth factor beta receptor signaling pathway
cytoplasm; nuclear matrix; nucleus; protein-containing complex
DNA-binding transcription factor binding metal ion binding
Mus musculus
Acetylation Cytoplasm Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger
MSDSPAGSNP
MSDSPAGSNPRTPESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTTSSSSSSPGDKAGFRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAGELDKKEQEAKPSPEPAAGSRGSGGDSAHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPTGPSLKASGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ
adherens junction assembly cellular response to estradiol stimulus mammary gland epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of homotypic cell-cell adhesion positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial to mesenchymal transition positive regulation of mammary gland epithelial cell proliferation regulation of canonical Wnt signaling pathway regulation of cell cycle regulation of DNA-templated transcription regulation of transforming growth factor beta receptor signaling pathway cytoplasm; nuclear matrix; nucleus; protein-containing complex DNA-binding transcription factor binding metal ion binding Mus musculus Acetylation Cytoplasm Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger MSDSPAGSNP MSDSPAGSNPRTPESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTTSSSSSSPGDKAGFRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAGELDKKEQEAKPSPEPAAGSRGSGGDSAHGGPEATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPTGPSLKASGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ
DNA repair DNA repair-dependent chromatin remodeling negative regulation of DNA-templated transcription positive regulation of heterochromatin formation positive regulation of transcription by RNA polymerase II
NuA4 histone acetyltransferase complex; nucleus; pericentric heterochromatin; site of double-strand break
histone H3K4 acetyltransferase activity histone H4K16 acetyltransferase activity metal ion binding peptide 2-hydroxyisobutyryltransferase activity peptide butyryltransferase activity peptide crotonyltransferase activity transcription coregulator activity
Cryptococcus neoformans var. neoformans serotype D
Acetylation Activator Chromatin regulator Chromosome DNA damage DNA repair Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Zinc Zinc-finger
MSPSAPSTPH
MSPSAPSTPHGRGSGSEPGTPAPSVAAGGSYTIDDVVPGVKIYVIKPLSNGQAEQRRAEILSTRPKPKPSAFAPPPPPNAPSPDPRDDTEYYVHYVEFNKRLDEWVGGSRLVLSKEMEWPKSKDEPKKKDRPAKAQPSKAPSRATGSPIPSDSLLKKAANKAAMAAGKATPGKAMPSSKLGKASKIGKAGKFPQKRKAKTEADTEAEEESNEDNDALGEEEDMDEDGDVTLITSDGAIDPSREVVAAPSNPRAAPQVFSKKQEIEKLRTSGSMTQSHSEISRVKNLNKLQIGKHEVETWYFSPYPIEYAHLPVLYICEFCLLYYPSATQLRRHRAKCTLLHPPGNEIYRHEGISFFEIDGRKQRTWCRNLCLISKCFLDHKTLYYDVDPFLYYCMTVKDDYGCHLIGYFSKEKESAEGYNVACILTLPQHQRKGYGRLLIEFSYELSKVEGKLGSPEKPLSDLGLLGYRAYWQEKIVELLLDSDYEISLDEIAQKTSITHGDIMHTCQALQMIKYYKNSHIIHLTDAVIEQHKKTKAKPRRAINPAYLKWKPPVFSRAQLAFGF
DNA repair DNA repair-dependent chromatin remodeling negative regulation of DNA-templated transcription positive regulation of heterochromatin formation positive regulation of transcription by RNA polymerase II NuA4 histone acetyltransferase complex; nucleus; pericentric heterochromatin; site of double-strand break histone H3K4 acetyltransferase activity histone H4K16 acetyltransferase activity metal ion binding peptide 2-hydroxyisobutyryltransferase activity peptide butyryltransferase activity peptide crotonyltransferase activity transcription coregulator activity Cryptococcus neoformans var. neoformans serotype D Acetylation Activator Chromatin regulator Chromosome DNA damage DNA repair Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Zinc Zinc-finger MSPSAPSTPH MSPSAPSTPHGRGSGSEPGTPAPSVAAGGSYTIDDVVPGVKIYVIKPLSNGQAEQRRAEILSTRPKPKPSAFAPPPPPNAPSPDPRDDTEYYVHYVEFNKRLDEWVGGSRLVLSKEMEWPKSKDEPKKKDRPAKAQPSKAPSRATGSPIPSDSLLKKAANKAAMAAGKATPGKAMPSSKLGKASKIGKAGKFPQKRKAKTEADTEAEEESNEDNDALGEEEDMDEDGDVTLITSDGAIDPSREVVAAPSNPRAAPQVFSKKQEIEKLRTSGSMTQSHSEISRVKNLNKLQIGKHEVETWYFSPYPIEYAHLPVLYICEFCLLYYPSATQLRRHRAKCTLLHPPGNEIYRHEGISFFEIDGRKQRTWCRNLCLISKCFLDHKTLYYDVDPFLYYCMTVKDDYGCHLIGYFSKEKESAEGYNVACILTLPQHQRKGYGRLLIEFSYELSKVEGKLGSPEKPLSDLGLLGYRAYWQEKIVELLLDSDYEISLDEIAQKTSITHGDIMHTCQALQMIKYYKNSHIIHLTDAVIEQHKKTKAKPRRAINPAYLKWKPPVFSRAQLAFGF
DNA repair DNA repair-dependent chromatin remodeling positive regulation of heterochromatin formation regulation of DNA-templated transcription
NuA4 histone acetyltransferase complex; nucleus; pericentric heterochromatin; site of double-strand break
histone H3K4 acetyltransferase activity metal ion binding peptide 2-hydroxyisobutyryltransferase activity peptide butyryltransferase activity peptide crotonyltransferase activity
Cryptococcus neoformans var. neoformans serotype D
Acetylation Activator Chromatin regulator Chromosome DNA damage DNA repair Metal-binding Nucleus Transcription Transcription regulation Transferase Zinc Zinc-finger
MSPSAPSTPH
MSPSAPSTPHGRGSGSEPGTPAPSVAAGGSYTIDDVVPGVKIYVIKPLSNGQAEQRRAEILSTRPKPKPSAFAPPPPPNAPSPDPRDDTEYYVHYVEFNKRLDEWVGGSRLVLSKEMEWPKSKDEPKKKDRPAKAQPSKAPSRATGSPIPSDSLLKKAANKAAMAAGKATPGKAMPSSKLGKASKIGKAGKFPQKRKAKTEADTEAEEESNEDNDALGEEEDMDEDGDVTLITSDGAIDPSREVVAAPSNPRAAPQVFSKKQEIEKLRTSGSMTQSHSEISRVKNLNKLQIGKHEVETWYFSPYPIEYAHLPVLYICEFCLLYYPSATQLRRHRAKCTLLHPPGNEIYRHEGISFFEIDGRKQRTWCRNLCLISKCFLDHKTLYYDVDPFLYYCMTVKDDYGCHLIGYFSKEKESAEGYNVACILTLPQHQRKGYGRLLIEFSYELSKVEGKLGSPEKPLSDLGLLGYRAYWQEKIVELLLDSDYEISLDEIAQKTSITHGDIMHTCQALQMIKYYKNSHIIHLTDAVIEQHKKTKAKPRRAINPAYLKWKPPVFSRAQLAFGF
DNA repair DNA repair-dependent chromatin remodeling positive regulation of heterochromatin formation regulation of DNA-templated transcription NuA4 histone acetyltransferase complex; nucleus; pericentric heterochromatin; site of double-strand break histone H3K4 acetyltransferase activity metal ion binding peptide 2-hydroxyisobutyryltransferase activity peptide butyryltransferase activity peptide crotonyltransferase activity Cryptococcus neoformans var. neoformans serotype D Acetylation Activator Chromatin regulator Chromosome DNA damage DNA repair Metal-binding Nucleus Transcription Transcription regulation Transferase Zinc Zinc-finger MSPSAPSTPH MSPSAPSTPHGRGSGSEPGTPAPSVAAGGSYTIDDVVPGVKIYVIKPLSNGQAEQRRAEILSTRPKPKPSAFAPPPPPNAPSPDPRDDTEYYVHYVEFNKRLDEWVGGSRLVLSKEMEWPKSKDEPKKKDRPAKAQPSKAPSRATGSPIPSDSLLKKAANKAAMAAGKATPGKAMPSSKLGKASKIGKAGKFPQKRKAKTEADTEAEEESNEDNDALGEEEDMDEDGDVTLITSDGAIDPSREVVAAPSNPRAAPQVFSKKQEIEKLRTSGSMTQSHSEISRVKNLNKLQIGKHEVETWYFSPYPIEYAHLPVLYICEFCLLYYPSATQLRRHRAKCTLLHPPGNEIYRHEGISFFEIDGRKQRTWCRNLCLISKCFLDHKTLYYDVDPFLYYCMTVKDDYGCHLIGYFSKEKESAEGYNVACILTLPQHQRKGYGRLLIEFSYELSKVEGKLGSPEKPLSDLGLLGYRAYWQEKIVELLLDSDYEISLDEIAQKTSITHGDIMHTCQALQMIKYYKNSHIIHLTDAVIEQHKKTKAKPRRAINPAYLKWKPPVFSRAQLAFGF
cellular response to oxidative stress osmosensory signaling pathway phosphorylation stress-activated MAPK cascade
cytoplasm; nucleus
ATP binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase activity
Cryptococcus neoformans var. neoformans serotype D
Activator ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase
MADFVKLSIF
MADFVKLSIFGTVFEVTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQSLPKREKVPFSTKFPNADPVSLDLLEKMLVFDPRTRISAAEGLAHEYLAPYHDPTDEPVAAEVFDWSFNDADLPVDTWKVMMYSEILDFHNLGDISQNEAEGPVTGEVPAAPAS
cellular response to oxidative stress osmosensory signaling pathway phosphorylation stress-activated MAPK cascade cytoplasm; nucleus ATP binding MAP kinase activity protein serine kinase activity protein serine/threonine kinase activity Cryptococcus neoformans var. neoformans serotype D Activator ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase MADFVKLSIF MADFVKLSIFGTVFEVTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQSLPKREKVPFSTKFPNADPVSLDLLEKMLVFDPRTRISAAEGLAHEYLAPYHDPTDEPVAAEVFDWSFNDADLPVDTWKVMMYSEILDFHNLGDISQNEAEGPVTGEVPAAPAS
autophagosome assembly nucleophagy phosphorylation piecemeal microautophagy of the nucleus protein transport regulation of autophagy response to starvation reticulophagy
autophagosome; cytoplasm; cytosol; phagophore assembly site; phagophore assembly site membrane
ATP binding protein serine kinase activity protein serine/threonine kinase activity
Cryptococcus neoformans var. neoformans serotype D
ATP-binding Autophagy Cytoplasm Kinase Membrane Nucleotide-binding Protein transport Reference proteome Serine/threonine-protein kinase Transferase Transport
MPDSNAQGSR
MPDSNAQGSREKESGHHRSHKERIGNYVVGAEIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLLENLESEINILKVINHRNIVALTDCFKNDTHIYLVMEYCSGSDLSVYIKQRGNIPTLDFVPKAGSSMALLPTDDEGKIYWPHPPTGGLDERVTRSFLGQLAQAIKFLRAQDLMHRDIKPQNLLLQPATETEVAEGHPYGIPVLKVADFGFARILPAAAMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLFEMSVGRPPFRANNHVELLRRIEKSNDNIVFPDEKERDSKSSDETSIPVPSDIKALIRALLKRKPNDRMGFDDFFNCGVWDGHMAESTEEESLSLDVSTDSSAGLGESDRIRQMVASTEQSKDRLIPTRAPQPLAADAALNPQPAVPISRDTSEGRSRLSTPPSRPTPTRRSTPKYYVGDATPSEPTAIIPPSPSSAPTPTSAPDPGLTTQQSPTSRANPRPIITAASSAQRRMSGKGDGREASSVEEAAPITPPFAGPSPTMARPSRGINEGSPLAAAPPITMGPDGRLERSSALEGSTSGVGTDYVVVEKQTVEINALADELDQASKRPMIRRSSRGSVVSRPVSSFKPISPNIAKNDPTLGPISYSPPFALSSTPPFAMQVPRHASGGNSFPRNPSIPSSLNAFPPTTISASPSYGQDAAARFGVSPGSLQTGALARALTNTAIRLIGTSANTAATAIARATAKRRPNIVRVSDMDAAEDDLLCTVEDLARKAFVLFELADERLLAQTQLAQTARTSSTPTGLTGTTPPFSMQAAAAAQAGSRRKSSSSSMNSEVWILRQQEAAANDAVVLYMKSLAFIVKAMDKVKRYWKNRTDVYDGYVASQELNEMGQWLRARFNETFEKAEWAKTQAGDTLLFPDWLVHDKARDTSRQAAVAELQGDLTTAEQGYETSLWLLQALLDESVYENGSIPDEDKVAYDRLMVPIKTRLDALRKKLAESSGMTAR
autophagosome assembly nucleophagy phosphorylation piecemeal microautophagy of the nucleus protein transport regulation of autophagy response to starvation reticulophagy autophagosome; cytoplasm; cytosol; phagophore assembly site; phagophore assembly site membrane ATP binding protein serine kinase activity protein serine/threonine kinase activity Cryptococcus neoformans var. neoformans serotype D ATP-binding Autophagy Cytoplasm Kinase Membrane Nucleotide-binding Protein transport Reference proteome Serine/threonine-protein kinase Transferase Transport MPDSNAQGSR MPDSNAQGSREKESGHHRSHKERIGNYVVGAEIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLLENLESEINILKVINHRNIVALTDCFKNDTHIYLVMEYCSGSDLSVYIKQRGNIPTLDFVPKAGSSMALLPTDDEGKIYWPHPPTGGLDERVTRSFLGQLAQAIKFLRAQDLMHRDIKPQNLLLQPATETEVAEGHPYGIPVLKVADFGFARILPAAAMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLFEMSVGRPPFRANNHVELLRRIEKSNDNIVFPDEKERDSKSSDETSIPVPSDIKALIRALLKRKPNDRMGFDDFFNCGVWDGHMAESTEEESLSLDVSTDSSAGLGESDRIRQMVASTEQSKDRLIPTRAPQPLAADAALNPQPAVPISRDTSEGRSRLSTPPSRPTPTRRSTPKYYVGDATPSEPTAIIPPSPSSAPTPTSAPDPGLTTQQSPTSRANPRPIITAASSAQRRMSGKGDGREASSVEEAAPITPPFAGPSPTMARPSRGINEGSPLAAAPPITMGPDGRLERSSALEGSTSGVGTDYVVVEKQTVEINALADELDQASKRPMIRRSSRGSVVSRPVSSFKPISPNIAKNDPTLGPISYSPPFALSSTPPFAMQVPRHASGGNSFPRNPSIPSSLNAFPPTTISASPSYGQDAAARFGVSPGSLQTGALARALTNTAIRLIGTSANTAATAIARATAKRRPNIVRVSDMDAAEDDLLCTVEDLARKAFVLFELADERLLAQTQLAQTARTSSTPTGLTGTTPPFSMQAAAAAQAGSRRKSSSSSMNSEVWILRQQEAAANDAVVLYMKSLAFIVKAMDKVKRYWKNRTDVYDGYVASQELNEMGQWLRARFNETFEKAEWAKTQAGDTLLFPDWLVHDKARDTSRQAAVAELQGDLTTAEQGYETSLWLLQALLDESVYENGSIPDEDKVAYDRLMVPIKTRLDALRKKLAESSGMTAR
cytoplasm protein quality control by the ubiquitin-proteasome system DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling negative regulation of SREBP signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process via the N-end rule pathway
chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex
ATP binding proteasome binding single-stranded DNA binding single-stranded DNA helicase activity ubiquitin conjugating enzyme activity
Cryptococcus neoformans var. neoformans serotype D
ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway
MSTAAKRRLI
MSTAAKRRLIRDFKRLTSDAPIGISGSPNPDNIMVWNAVIFGPPETPFEDGSFRLTLTFTDAYPNKPPTVRFISKMFHPNIYANGELCLDILQNRWSPTYDVAAILTSVQSLLNDPNPASPANVDAAQLFKENLKEYERRVKKTVELSWVDNADEIEAEVVEADEGSSS
cytoplasm protein quality control by the ubiquitin-proteasome system DNA repair DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling negative regulation of SREBP signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process via the N-end rule pathway chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex ATP binding proteasome binding single-stranded DNA binding single-stranded DNA helicase activity ubiquitin conjugating enzyme activity Cryptococcus neoformans var. neoformans serotype D ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway MSTAAKRRLI MSTAAKRRLIRDFKRLTSDAPIGISGSPNPDNIMVWNAVIFGPPETPFEDGSFRLTLTFTDAYPNKPPTVRFISKMFHPNIYANGELCLDILQNRWSPTYDVAAILTSVQSLLNDPNPASPANVDAAQLFKENLKEYERRVKKTVELSWVDNADEIEAEVVEADEGSSS
cytoplasm protein quality control by the ubiquitin-proteasome system DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling negative regulation of SREBP signaling pathway protein ubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process via the N-end rule pathway
chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex
ATP binding proteasome binding single-stranded DNA binding single-stranded DNA helicase activity ubiquitin conjugating enzyme activity
Cryptococcus neoformans var. neoformans serotype D
ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway
MSTAAKRRLI
MSTAAKRRLIRDFKRLTSDAPIGISGSPNPDNIMVWNAVIFGPPETPFEDGSFRLTLTFTDAYPNKPPTVRFISKMFHPNIYANGELCLDILQNRWSPTYDVAAILTSVQSLLNDPNPASPANVDAAQLFKENLKEYERRVKKTVELSWVDNADEIEAEVVEADEGSSS
cytoplasm protein quality control by the ubiquitin-proteasome system DNA-templated transcription termination double-strand break repair via homologous recombination error-free postreplication DNA repair error-free translesion synthesis error-prone translesion synthesis meiotic DNA double-strand break formation mitotic G1 DNA damage checkpoint signaling negative regulation of SREBP signaling pathway protein ubiquitination regulation of dipeptide transport sporulation resulting in formation of a cellular spore stress-induced homeostatically regulated protein degradation pathway subtelomeric heterochromatin formation telomere maintenance via recombination transcription by RNA polymerase II ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process via the N-end rule pathway chromosome, telomeric region; cytoplasm; HULC complex; MUB1-RAD6-UBR2 ubiquitin ligase complex; nucleus; Rad6-Rad18 complex; RAD6-UBR2 ubiquitin ligase complex; UBR1-RAD6 ubiquitin ligase complex ATP binding proteasome binding single-stranded DNA binding single-stranded DNA helicase activity ubiquitin conjugating enzyme activity Cryptococcus neoformans var. neoformans serotype D ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway MSTAAKRRLI MSTAAKRRLIRDFKRLTSDAPIGISGSPNPDNIMVWNAVIFGPPETPFEDGSFRLTLTFTDAYPNKPPTVRFISKMFHPNIYANGELCLDILQNRWSPTYDVAAILTSVQSLLNDPNPASPANVDAAQLFKENLKEYERRVKKTVELSWVDNADEIEAEVVEADEGSSS
negative regulation of filamentous growth negative regulation of transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process, non-stop decay phosphorylation positive regulation of transcription from RNA polymerase II promoter by galactose protein destabilization
CKM complex; mediator complex; nucleus
ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity
Cryptococcus neoformans var. neoformans serotype D
Activator ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome Repressor Serine/threonine-protein kinase Transcription Transcription regulation Transferase
MATIPGGGTI
MATIPGGGTIMDPMHLYRARRDKERRGVLKTYKILGFISSGTYGRVYKAVLLPPPKTASAKSALPSSTRAALSLPKDKLPSPSFTEDSDPLNNPEMCMRPGDRPAKRGDVFAIKKFKPDKEGDVLTYAGISQSGAREIMLNRELHHRNLVSLREVILEDKSIYMVFEYAEHDFLQIIHYHSQTARASIPPSTLRRLLHQLLCGVHFLHSNFVLHRDLKPANILVTSQGVVKIGDLGLARLWHKPLAQQGLYGGDKVVVTIWYRAPELILGAKHYTAAVDIWAVGCIYAELLSLRPIFKGDEAKMDGKKSLPFQRDQMGKICEVLGPVKPEQWPGIVHMPEYRTYQATGPYPHSNPLAPWYHARSNSSEGYDILVKMFEWDPARRITARDALRHPWFQEEGGVDTKSVFEGSSITYPTRRVTHEDNGDAKMGSLPQSMAGGRLPSSSNFRPASGNIVQPAARKKARI
negative regulation of filamentous growth negative regulation of transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process, non-stop decay phosphorylation positive regulation of transcription from RNA polymerase II promoter by galactose protein destabilization CKM complex; mediator complex; nucleus ATP binding cyclin-dependent protein serine/threonine kinase activity metal ion binding protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity Cryptococcus neoformans var. neoformans serotype D Activator ATP-binding Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Reference proteome Repressor Serine/threonine-protein kinase Transcription Transcription regulation Transferase MATIPGGGTI MATIPGGGTIMDPMHLYRARRDKERRGVLKTYKILGFISSGTYGRVYKAVLLPPPKTASAKSALPSSTRAALSLPKDKLPSPSFTEDSDPLNNPEMCMRPGDRPAKRGDVFAIKKFKPDKEGDVLTYAGISQSGAREIMLNRELHHRNLVSLREVILEDKSIYMVFEYAEHDFLQIIHYHSQTARASIPPSTLRRLLHQLLCGVHFLHSNFVLHRDLKPANILVTSQGVVKIGDLGLARLWHKPLAQQGLYGGDKVVVTIWYRAPELILGAKHYTAAVDIWAVGCIYAELLSLRPIFKGDEAKMDGKKSLPFQRDQMGKICEVLGPVKPEQWPGIVHMPEYRTYQATGPYPHSNPLAPWYHARSNSSEGYDILVKMFEWDPARRITARDALRHPWFQEEGGVDTKSVFEGSSITYPTRRVTHEDNGDAKMGSLPQSMAGGRLPSSSNFRPASGNIVQPAARKKARI
proteolysis
extracellular region
aspartic-type endopeptidase activity metal ion binding
Candida albicans
3D-structure Aspartyl protease Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen
MFLKNIFIAL
MFLKNIFIALAIALLVDATPTTTKRSAGFVALDFSVVKTPKAFPVTNGQEGKTSKRQAVPVTLHNEQVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSIDQGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAATGQIIFGGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTINTDNVDVLLDSGTTITYLQQDLADQIIKAFNGKLTQDSNGNSFYEVDCNLSGDVVFNFSKNAKISVPASEFAASLQGDDGQPYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLAQVKYTSASSISALT
proteolysis extracellular region aspartic-type endopeptidase activity metal ion binding Candida albicans 3D-structure Aspartyl protease Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen MFLKNIFIAL MFLKNIFIALAIALLVDATPTTTKRSAGFVALDFSVVKTPKAFPVTNGQEGKTSKRQAVPVTLHNEQVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSIDQGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAATGQIIFGGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTINTDNVDVLLDSGTTITYLQQDLADQIIKAFNGKLTQDSNGNSFYEVDCNLSGDVVFNFSKNAKISVPASEFAASLQGDDGQPYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLAQVKYTSASSISALT
chaperone cofactor-dependent protein refolding intracellular protein transport mitochondrial cytochrome c oxidase assembly mitochondrial DNA metabolic process negative regulation of mitochondrial translation protein import into mitochondrial matrix protein refolding protein stabilization protein unfolding regulation of DNA recombination
cytoplasm; endodeoxyribonuclease complex; mitochondrial inner membrane; mitochondrial nucleoid; mitochondrion; PAM complex, Tim23 associated import motor; TIM23 mitochondrial import inner membrane translocase complex
ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone enzyme regulator activity heat shock protein binding mitochondrial protein-transporting ATPase activity protein folding chaperone unfolded protein binding
Saccharomyces cerevisiae
ATP-binding Chaperone Direct protein sequencing Hydrolase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Stress response Transit peptide
MLAAKNILNR
MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNNAESGETKQ
chaperone cofactor-dependent protein refolding intracellular protein transport mitochondrial cytochrome c oxidase assembly mitochondrial DNA metabolic process negative regulation of mitochondrial translation protein import into mitochondrial matrix protein refolding protein stabilization protein unfolding regulation of DNA recombination cytoplasm; endodeoxyribonuclease complex; mitochondrial inner membrane; mitochondrial nucleoid; mitochondrion; PAM complex, Tim23 associated import motor; TIM23 mitochondrial import inner membrane translocase complex ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone enzyme regulator activity heat shock protein binding mitochondrial protein-transporting ATPase activity protein folding chaperone unfolded protein binding Saccharomyces cerevisiae ATP-binding Chaperone Direct protein sequencing Hydrolase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Stress response Transit peptide MLAAKNILNR MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNNAESGETKQ
protein transport regulation of proteolysis vacuole fusion, non-autophagic
cytoplasm; cytosol; fungal-type vacuole; membrane fusion priming complex; nucleus
endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity
Saccharomyces cerevisiae
Cytoplasm Direct protein sequencing Phosphoprotein Protease inhibitor Protein transport Reference proteome Serine protease inhibitor Transport
MTKNFIVTLK
MTKNFIVTLKKNTPDVEAKKFLDSVHHAGGSIVHEFDIIKGYTIKVPDVLHLNKLKEKHNDVIENVEEDKEVHTN
protein transport regulation of proteolysis vacuole fusion, non-autophagic cytoplasm; cytosol; fungal-type vacuole; membrane fusion priming complex; nucleus endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Phosphoprotein Protease inhibitor Protein transport Reference proteome Serine protease inhibitor Transport MTKNFIVTLK MTKNFIVTLKKNTPDVEAKKFLDSVHHAGGSIVHEFDIIKGYTIKVPDVLHLNKLKEKHNDVIENVEEDKEVHTN
actin filament bundle assembly response to alkaline pH response to bacterium response to reactive oxygen species translation translational elongation
cell cortex; cytosol; extracellular matrix; filopodium; lamellipodium; phagocytic vesicle; pseudopodium
actin filament binding actin monomer binding calcium-dependent protein binding GTP binding GTPase activity translation elongation factor activity
Dictyostelium discoideum
Actin-binding Cytoplasm Direct protein sequencing Elongation factor GTP-binding Hydrolase Nucleotide-binding Protein biosynthesis Reference proteome
MGKEKTHINI
MGKEKTHINIVVIGHVDAGKSTTTGHLIYKCGGIDKRVIEKYEKEASEMGKQSFKYAWVMDKLKAERERGITIDIALWKFETSKYYFTIIDAPGHRDFIKNMITGTSQADCAVLVIASPTGEFEAGIAKNGQTREHALLAYTLGVKQMIVAINKMDEKSTNYSQARYDEIVKEVSSFIKKIGYNPEKVAFVPISGWNGDNMLERSDKMEWYKGPTLLEALDAIVEPKRPHDKPLRIPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGDNVGFNVKNVSVKEIKRGMVAGDSKNDPPQETEKFVAQVIVLNHPGQIHAGYSPVLDCHTAHIACKFTEIVDKVDRRTGAVVAKEGTAAVVLKNGDAAMVELTPSRPMCVESFTEYPPLGRFAVRDMRQTVAVGVIKSTVKKAPGKAGDKKGAAAPSKKK
actin filament bundle assembly response to alkaline pH response to bacterium response to reactive oxygen species translation translational elongation cell cortex; cytosol; extracellular matrix; filopodium; lamellipodium; phagocytic vesicle; pseudopodium actin filament binding actin monomer binding calcium-dependent protein binding GTP binding GTPase activity translation elongation factor activity Dictyostelium discoideum Actin-binding Cytoplasm Direct protein sequencing Elongation factor GTP-binding Hydrolase Nucleotide-binding Protein biosynthesis Reference proteome MGKEKTHINI MGKEKTHINIVVIGHVDAGKSTTTGHLIYKCGGIDKRVIEKYEKEASEMGKQSFKYAWVMDKLKAERERGITIDIALWKFETSKYYFTIIDAPGHRDFIKNMITGTSQADCAVLVIASPTGEFEAGIAKNGQTREHALLAYTLGVKQMIVAINKMDEKSTNYSQARYDEIVKEVSSFIKKIGYNPEKVAFVPISGWNGDNMLERSDKMEWYKGPTLLEALDAIVEPKRPHDKPLRIPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGDNVGFNVKNVSVKEIKRGMVAGDSKNDPPQETEKFVAQVIVLNHPGQIHAGYSPVLDCHTAHIACKFTEIVDKVDRRTGAVVAKEGTAAVVLKNGDAAMVELTPSRPMCVESFTEYPPLGRFAVRDMRQTVAVGVIKSTVKKAPGKAGDKKGAAAPSKKK
actin filament bundle assembly response to alkaline pH translation translational elongation
cell cortex; cytosol; filopodium; lamellipodium; lipid droplet; phagocytic vesicle; pseudopodium
actin filament binding actin monomer binding GTP binding GTPase activity translation elongation factor activity
Dictyostelium discoideum
Actin-binding Cytoplasm Direct protein sequencing Elongation factor GTP-binding Nucleotide-binding Protein biosynthesis Reference proteome
MGKEKTHINI
MGKEKTHINIVVIGHVDAGKSTTTGHLIYKCGGIDKRVIEKYEKEASEMGKQSFKYAWVMDKLKAERERGITIDIALWKFETSKYYFTIIDAPGHRDFIKNMITGTSQADCAVLVIASPTGEFEAGIAKNGQTREHALLAYTLGVKQMIVAINKMDEKSTNYSQARYDEIVKEVSSFIKKIGYNPEKVAFVPISGWNGDNMLERSDKMEWYKGPTLLEALDAIVEPKRPHDKPLRIPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGDNVGFNVKNVSVKEIKRGMVAGDSKNDPPQETEKFVAQVIVLNHPGQIHAGYSPVLDCHTAHIACKFTEIVDKVDRRTGAVVAKEGTAAVVLKNGDAAMVELTPSRPMCVESFTEYPPLGRFAVRDMRQTVAVGVIKSTVKKAPGKAGDKKGAAAPSKKK
actin filament bundle assembly response to alkaline pH translation translational elongation cell cortex; cytosol; filopodium; lamellipodium; lipid droplet; phagocytic vesicle; pseudopodium actin filament binding actin monomer binding GTP binding GTPase activity translation elongation factor activity Dictyostelium discoideum Actin-binding Cytoplasm Direct protein sequencing Elongation factor GTP-binding Nucleotide-binding Protein biosynthesis Reference proteome MGKEKTHINI MGKEKTHINIVVIGHVDAGKSTTTGHLIYKCGGIDKRVIEKYEKEASEMGKQSFKYAWVMDKLKAERERGITIDIALWKFETSKYYFTIIDAPGHRDFIKNMITGTSQADCAVLVIASPTGEFEAGIAKNGQTREHALLAYTLGVKQMIVAINKMDEKSTNYSQARYDEIVKEVSSFIKKIGYNPEKVAFVPISGWNGDNMLERSDKMEWYKGPTLLEALDAIVEPKRPHDKPLRIPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGDNVGFNVKNVSVKEIKRGMVAGDSKNDPPQETEKFVAQVIVLNHPGQIHAGYSPVLDCHTAHIACKFTEIVDKVDRRTGAVVAKEGTAAVVLKNGDAAMVELTPSRPMCVESFTEYPPLGRFAVRDMRQTVAVGVIKSTVKKAPGKAGDKKGAAAPSKKK
lipid catabolic process xylan catabolic process
extracellular region
acetylxylan esterase activity triglyceride lipase activity
Sodiomyces alcalophilus
Carbohydrate metabolism Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Polysaccharide degradation Secreted Serine esterase Signal Xylan degradation
MRLAPQKPLL
MRLAPQKPLLLSTVLHLLLSIWMLGFASLAGATVQEPLAASDTPKPVSAALFSSIERLSRLVDITYCVGNTGVWKPFACASRCNEFPTLTLERTWRTGILMSDSCGLIAVDHGTPRHDAGEGKDDPLAEKAIIVAFRGTYSLTNTIIDLSTIPQEYVPYPSPDDGGNEPPREPSHRCDNCTVHSGFLASWRHARKVVLPELKVLRQKYPEYPIRLVGHSLGGAVAMLAALEMRVSLGWRDTVVTTFGEPRVGNRQLCDYLNAVFELNLGDEMDPAEREYRRVTHADDPVPLLPPAEWGYSSHGGEFFISKKDLPPSVEDVLVCHGDHDENCIARGKSSAVSVPAGDYDDALSTLEEQDVMLADALPWIPARLKLWELFFAHRDYFWRLGLCVPGGDPANWGRKGGEGAAESISAEG
lipid catabolic process xylan catabolic process extracellular region acetylxylan esterase activity triglyceride lipase activity Sodiomyces alcalophilus Carbohydrate metabolism Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Polysaccharide degradation Secreted Serine esterase Signal Xylan degradation MRLAPQKPLL MRLAPQKPLLLSTVLHLLLSIWMLGFASLAGATVQEPLAASDTPKPVSAALFSSIERLSRLVDITYCVGNTGVWKPFACASRCNEFPTLTLERTWRTGILMSDSCGLIAVDHGTPRHDAGEGKDDPLAEKAIIVAFRGTYSLTNTIIDLSTIPQEYVPYPSPDDGGNEPPREPSHRCDNCTVHSGFLASWRHARKVVLPELKVLRQKYPEYPIRLVGHSLGGAVAMLAALEMRVSLGWRDTVVTTFGEPRVGNRQLCDYLNAVFELNLGDEMDPAEREYRRVTHADDPVPLLPPAEWGYSSHGGEFFISKKDLPPSVEDVLVCHGDHDENCIARGKSSAVSVPAGDYDDALSTLEEQDVMLADALPWIPARLKLWELFFAHRDYFWRLGLCVPGGDPANWGRKGGEGAAESISAEG
linoleic acid metabolic process lipid oxidation
extracellular region
linoleate 11-lipoxygenase activity linoleate 9S-lipoxygenase activity metal ion binding
Nakataea oryzae
Dioxygenase Glycoprotein Manganese Metal-binding Oxidoreductase Secreted Signal
MRIGLLAFAV
MRIGLLAFAVAARYVEALPVASGEEVASSSAPTTLPSTSSSSALPSPTKYTLPHEDPNPEARKAEIALKRGGFLYGPSTLGQTTFYPSGTLGTAMSQRDQALWLRDAENQTITAYREANETLRDIQSHGGLKTLDDFALLYDGHWKASVPEGIEKGMLSNYTSDLLFSMERLSNNPYSLKRLHPTKDKLPFSVEDKVVKQLTATTLAALHKAGRLFFVDHSDQKKYTPQAGRYAAACQGLFYVDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTVPEIVHMAAIRTLSESHPVLAVLNRIMYQAYAIRPVGERILFNPGGFWDQNLGLPATAAVDFLSSIYAHGEGGFRAGYVENNLRKRGLVGDTFGGPALPHFPFYEDAQRVLGAIRGFMQAFVDSTYGGDDGALARDFELQDWVAEANGPAQVRDFPTAPLRRREELVGILTHIAWNTGGAHHVLNQGAPVRASGVLPLHPAALYAPVPAAKGAVASSDGLLAWLPDEVKSVEQVSLLARFNRAQVRDRNQTVRNMFAAPELLAGNGEAYAAANARFVEETGRISREIEGRGFDSKGLSQGMPFIWTALNPAVNPFFLSI
linoleic acid metabolic process lipid oxidation extracellular region linoleate 11-lipoxygenase activity linoleate 9S-lipoxygenase activity metal ion binding Nakataea oryzae Dioxygenase Glycoprotein Manganese Metal-binding Oxidoreductase Secreted Signal MRIGLLAFAV MRIGLLAFAVAARYVEALPVASGEEVASSSAPTTLPSTSSSSALPSPTKYTLPHEDPNPEARKAEIALKRGGFLYGPSTLGQTTFYPSGTLGTAMSQRDQALWLRDAENQTITAYREANETLRDIQSHGGLKTLDDFALLYDGHWKASVPEGIEKGMLSNYTSDLLFSMERLSNNPYSLKRLHPTKDKLPFSVEDKVVKQLTATTLAALHKAGRLFFVDHSDQKKYTPQAGRYAAACQGLFYVDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTVPEIVHMAAIRTLSESHPVLAVLNRIMYQAYAIRPVGERILFNPGGFWDQNLGLPATAAVDFLSSIYAHGEGGFRAGYVENNLRKRGLVGDTFGGPALPHFPFYEDAQRVLGAIRGFMQAFVDSTYGGDDGALARDFELQDWVAEANGPAQVRDFPTAPLRRREELVGILTHIAWNTGGAHHVLNQGAPVRASGVLPLHPAALYAPVPAAKGAVASSDGLLAWLPDEVKSVEQVSLLARFNRAQVRDRNQTVRNMFAAPELLAGNGEAYAAANARFVEETGRISREIEGRGFDSKGLSQGMPFIWTALNPAVNPFFLSI
cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress
cell surface; cytosol; nucleus
thioredoxin peroxidase activity
Candida albicans
Antioxidant Cytoplasm Disulfide bond Nucleus Oxidoreductase Peroxidase Redox-active center Reference proteome
MAPVVQQPAP
MAPVVQQPAPSFKKTAVVDGVFEEVTLEQYKGKWVLLAFIPLAFTFVCPSEIIAYSEAVKKFAEKDAQVLFASTDSEYTWLAWTNVARKDGGIGKVDFPVLADTNHSLSRDYGVLIEEEGVALRGIFLIDPKGVLRQITINDLPVGRSVEESLRLLEAFQFTEKYGEVCPANWHPGDETIKPSPEASKEYFNKVNK
cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress cell surface; cytosol; nucleus thioredoxin peroxidase activity Candida albicans Antioxidant Cytoplasm Disulfide bond Nucleus Oxidoreductase Peroxidase Redox-active center Reference proteome MAPVVQQPAP MAPVVQQPAPSFKKTAVVDGVFEEVTLEQYKGKWVLLAFIPLAFTFVCPSEIIAYSEAVKKFAEKDAQVLFASTDSEYTWLAWTNVARKDGGIGKVDFPVLADTNHSLSRDYGVLIEEEGVALRGIFLIDPKGVLRQITINDLPVGRSVEESLRLLEAFQFTEKYGEVCPANWHPGDETIKPSPEASKEYFNKVNK
blood coagulation camera-type eye development positive regulation of leukocyte chemotaxis proteolysis
endoplasmic reticulum; extracellular space
serine-type endopeptidase activity
Homo sapiens
Disease variant Disulfide bond Glycoprotein Hydrolase Microphthalmia Protease Reference proteome Serine protease Signal
MLLAVLLLLP
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQVLSAQGTQALQAAQRSAQWAINRVAMEIQHRSHECRGSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSASSSREPSCRELLAWDPPQELQADAARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLRRLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQKLAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGLEPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQP
blood coagulation camera-type eye development positive regulation of leukocyte chemotaxis proteolysis endoplasmic reticulum; extracellular space serine-type endopeptidase activity Homo sapiens Disease variant Disulfide bond Glycoprotein Hydrolase Microphthalmia Protease Reference proteome Serine protease Signal MLLAVLLLLP MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQVLSAQGTQALQAAQRSAQWAINRVAMEIQHRSHECRGSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSASSSREPSCRELLAWDPPQELQADAARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLRRLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQKLAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGLEPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQP
spermatid development
nuclear inner membrane
mannosyltransferase activity
Mus musculus
Developmental protein Differentiation Glycosyltransferase Membrane Nucleus Reference proteome Spermatogenesis Transferase Transmembrane Transmembrane helix
MVGPTRSKLR
MVGPTRSKLREGSSDRPQSSCTGQARRRWSAATMEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIQSLNAQNYFQLEEVAKLLLLNRFQFLFTLLDHFREKVQALQMHRFSHRTLFGLAIFVGILHWLHLITLFENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLMMGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTSTVHKKHYMALCFSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCGTIILKFLTSKICGVSDHIRLSDLIAARILRYTDFDTLIYTCAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTNTYVRKQLLDNAELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN
spermatid development nuclear inner membrane mannosyltransferase activity Mus musculus Developmental protein Differentiation Glycosyltransferase Membrane Nucleus Reference proteome Spermatogenesis Transferase Transmembrane Transmembrane helix MVGPTRSKLR MVGPTRSKLREGSSDRPQSSCTGQARRRWSAATMEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIQSLNAQNYFQLEEVAKLLLLNRFQFLFTLLDHFREKVQALQMHRFSHRTLFGLAIFVGILHWLHLITLFENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLMMGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTSTVHKKHYMALCFSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCGTIILKFLTSKICGVSDHIRLSDLIAARILRYTDFDTLIYTCAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTNTYVRKQLLDNAELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN
detoxification of cadmium ion
vacuolar membrane
ATP binding ATP hydrolysis activity metal ion binding P-type cadmium transporter activity P-type zinc transporter activity
Arabidopsis thaliana
ATP-binding Cadmium Magnesium Membrane Metal-binding Nucleotide-binding Translocase Transmembrane Transmembrane helix Vacuole Zinc
MAEGEESKKM
MAEGEESKKMNLQTSYFDVVGICCSSEVSIVGNVLRQVDGVKEFSVIVPSRTVIVVHDTFLISPLQIVKALNQARLEASVRPYGETSLKSQWPSPFAIVSGVLLVLSFFKYFYSPLEWLAIVAVVAGVFPILAKAVASVTRFRLDINALTLIAVIATLCMQDFTEAATIVFLFSVADWLESSAAHKASIVMSSLMSLAPRKAVIADTGLEVDVDEVGINTVVSVKAGESIPIDGVVVDGSCDVDEKTLTGESFPVSKQRESTVMAATINLNGYIKVKTTALARDCVVAKMTKLVEEAQKSQTKTQRFIDKCSRYYTPAVVVSAACFAVIPVLLKVQDLSHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGFLIKTGDCLETLAKIKIVAFDKTGTITKAEFMVSDFRSLSPSINLHKLLNWVSSIECKSSHPMAAALIDYAISVSVEPKPDIVENFQNFPGEGVYGRIDGQDIYIGNKRIAQRAGCLTDNVPDIEATMKRGKTIGYIYMGAKLTGSFNLLDGCRYGVAQALKELKSLGIQTAMLTGDNQDAAMSTQEQLENALDIVHSELLPQDKARIIDDFKIQGPTMMVGDGLNDAPALAKADIGISMGISGSALATETGDIILMSNDIRKIPKGMRLAKRSHKKVIENVVLSVSIKGAIMVLGFVGYPLVWAAVLADAGTCLLVILNSMILLRDEREAVSTCYRSSTSSPVKLEEDEVEDLEVGLLQKSEETSKKSCCSGCCSGPKDNQQK
detoxification of cadmium ion vacuolar membrane ATP binding ATP hydrolysis activity metal ion binding P-type cadmium transporter activity P-type zinc transporter activity Arabidopsis thaliana ATP-binding Cadmium Magnesium Membrane Metal-binding Nucleotide-binding Translocase Transmembrane Transmembrane helix Vacuole Zinc MAEGEESKKM MAEGEESKKMNLQTSYFDVVGICCSSEVSIVGNVLRQVDGVKEFSVIVPSRTVIVVHDTFLISPLQIVKALNQARLEASVRPYGETSLKSQWPSPFAIVSGVLLVLSFFKYFYSPLEWLAIVAVVAGVFPILAKAVASVTRFRLDINALTLIAVIATLCMQDFTEAATIVFLFSVADWLESSAAHKASIVMSSLMSLAPRKAVIADTGLEVDVDEVGINTVVSVKAGESIPIDGVVVDGSCDVDEKTLTGESFPVSKQRESTVMAATINLNGYIKVKTTALARDCVVAKMTKLVEEAQKSQTKTQRFIDKCSRYYTPAVVVSAACFAVIPVLLKVQDLSHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGFLIKTGDCLETLAKIKIVAFDKTGTITKAEFMVSDFRSLSPSINLHKLLNWVSSIECKSSHPMAAALIDYAISVSVEPKPDIVENFQNFPGEGVYGRIDGQDIYIGNKRIAQRAGCLTDNVPDIEATMKRGKTIGYIYMGAKLTGSFNLLDGCRYGVAQALKELKSLGIQTAMLTGDNQDAAMSTQEQLENALDIVHSELLPQDKARIIDDFKIQGPTMMVGDGLNDAPALAKADIGISMGISGSALATETGDIILMSNDIRKIPKGMRLAKRSHKKVIENVVLSVSIKGAIMVLGFVGYPLVWAAVLADAGTCLLVILNSMILLRDEREAVSTCYRSSTSSPVKLEEDEVEDLEVGLLQKSEETSKKSCCSGCCSGPKDNQQK
removal of superoxide radicals
periplasmic space
copper ion binding identical protein binding superoxide dismutase activity
Salmonella typhimurium
3D-structure Antioxidant Copper Disulfide bond Metal-binding Oxidoreductase Periplasm Reference proteome Signal Zinc
MKYTILSLVA
MKYTILSLVAGALISCSAMAENTLTVKMNDALSSGTGENIGEITVSETPYGLLFTPHLNGLTPGIHGFHVHTNPSCMPGMKDGKEVPALMAGGHLDPEKTGKHLGPYNDKGHLGDLPGLVVNADGTATYPLLAPRLKSLSELKGHSLMIHKGGDNYSDKPAPLGGGGARFACGVIEK
removal of superoxide radicals periplasmic space copper ion binding identical protein binding superoxide dismutase activity Salmonella typhimurium 3D-structure Antioxidant Copper Disulfide bond Metal-binding Oxidoreductase Periplasm Reference proteome Signal Zinc MKYTILSLVA MKYTILSLVAGALISCSAMAENTLTVKMNDALSSGTGENIGEITVSETPYGLLFTPHLNGLTPGIHGFHVHTNPSCMPGMKDGKEVPALMAGGHLDPEKTGKHLGPYNDKGHLGDLPGLVVNADGTATYPLLAPRLKSLSELKGHSLMIHKGGDNYSDKPAPLGGGGARFACGVIEK
cytoplasmic translation response to antibiotic response to cycloheximide
cytosol; cytosolic large ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Antibiotic resistance Cycloheximide resistance Cytoplasm Direct protein sequencing Methylation Reference proteome Ribonucleoprotein Ribosomal protein
MVNVPKTRKT
MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF
cytoplasmic translation response to antibiotic response to cycloheximide cytosol; cytosolic large ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Antibiotic resistance Cycloheximide resistance Cytoplasm Direct protein sequencing Methylation Reference proteome Ribonucleoprotein Ribosomal protein MVNVPKTRKT MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF
cytoplasmic translation response to antibiotic response to cycloheximide
cytosol; cytosolic large ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Antibiotic resistance Cycloheximide resistance Cytoplasm Direct protein sequencing Methylation Reference proteome Ribonucleoprotein Ribosomal protein
MVNVPKTRKT
MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF
cytoplasmic translation response to antibiotic response to cycloheximide cytosol; cytosolic large ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Antibiotic resistance Cycloheximide resistance Cytoplasm Direct protein sequencing Methylation Reference proteome Ribonucleoprotein Ribosomal protein MVNVPKTRKT MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF
maintenance of translational fidelity maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of translational fidelity translation
cytosol; cytosolic small ribosomal subunit; ribosome
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Hydroxylation Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MGKGKPRGLN
MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
maintenance of translational fidelity maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of translational fidelity translation cytosol; cytosolic small ribosomal subunit; ribosome structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Hydroxylation Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MGKGKPRGLN MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of translational fidelity translation
cytosol; cytosolic small ribosomal subunit; ribosome
structural constituent of ribosome
Saccharomyces cerevisiae
Cytoplasm Hydroxylation Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MGKGKPRGLN
MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of translational fidelity translation cytosol; cytosolic small ribosomal subunit; ribosome structural constituent of ribosome Saccharomyces cerevisiae Cytoplasm Hydroxylation Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MGKGKPRGLN MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
cytosol; cytosolic small ribosomal subunit; mitochondrion
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MSDAVTIRTR
MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytosol; cytosolic small ribosomal subunit; mitochondrion structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MSDAVTIRTR MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
cytosol; cytosolic small ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MSDAVTIRTR
MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytosol; cytosolic small ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MSDAVTIRTR MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
cytoplasmic translation translation
90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit
RNA binding rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MARGPKKHLK
MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
cytoplasmic translation translation 90S preribosome; cytoplasm; cytosol; cytosolic small ribosomal subunit RNA binding rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MARGPKKHLK MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
cytoplasmic translation translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
RNA binding rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MARGPKKHLK
MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
cytoplasmic translation translation 90S preribosome; cytosol; cytosolic small ribosomal subunit RNA binding rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MARGPKKHLK MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation
90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing Ubl conjugation
MKLNISYPVN
MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation 90S preribosome; cytosol; cytosolic small ribosomal subunit; nucleolus; nucleoplasm; small-subunit processome structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing Ubl conjugation MKLNISYPVN MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation
cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus; small-subunit processome
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing Ubl conjugation
MKLNISYPVN
MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation cytoplasm; cytosol; cytosolic small ribosomal subunit; nucleolus; small-subunit processome structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing Ubl conjugation MKLNISYPVN MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MGISRDSRHK
MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation 90S preribosome; cytosol; cytosolic small ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MGISRDSRHK MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MGISRDSRHK
MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation 90S preribosome; cytosol; cytosolic small ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MGISRDSRHK MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
large ribosomal subunit rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Methylation Reference proteome Ribonucleoprotein Ribosomal protein
MSGNGAQGTK
MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV
cytoplasmic translation cytosol; cytosolic large ribosomal subunit large ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Methylation Reference proteome Ribonucleoprotein Ribosomal protein MSGNGAQGTK MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit; nucleus
large ribosomal subunit rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
Acetylation Cytoplasm Methylation Reference proteome Ribonucleoprotein Ribosomal protein
MSGNGAQGTK
MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV
cytoplasmic translation cytosol; cytosolic large ribosomal subunit; nucleus large ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae Acetylation Cytoplasm Methylation Reference proteome Ribonucleoprotein Ribosomal protein MSGNGAQGTK MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV
cytoplasmic translation maturation of LSU-rRNA ribosomal large subunit export from nucleus
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MSKITSSQVR
MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
cytoplasmic translation maturation of LSU-rRNA ribosomal large subunit export from nucleus cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MSKITSSQVR MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
cytoplasmic translation maturation of LSU-rRNA ribosomal large subunit export from nucleus
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MSKITSSQVR
MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
cytoplasmic translation maturation of LSU-rRNA ribosomal large subunit export from nucleus cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MSKITSSQVR MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MGRVIRNQRK
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MGRVIRNQRK MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MGRVIRNQRK
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MGRVIRNQRK MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MSTELTVQSE
MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation 90S preribosome; cytosol; cytosolic small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MSTELTVQSE MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MSTELTVQSE
MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation 90S preribosome; cytosol; cytosolic small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MSTELTVQSE MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MGIDHTSKQH
MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKGKAPRILSTGRKFERARGRRRSKGFKV
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MGIDHTSKQH MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKGKAPRILSTGRKFERARGRRRSKGFKV
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MGIDHTSKQH
MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKGKAPRILSTGRKFERARGRRRSKGFKV
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MGIDHTSKQH MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMGPHKGKAPRILSTGRKFERARGRRRSKGFKV
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation
90S preribosome; cytosol; cytosolic small ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MSAVPSVQTF
MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation 90S preribosome; cytosol; cytosolic small ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MSAVPSVQTF MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR
cytoplasmic translation ribosomal large subunit assembly translation
cytosol; cytosolic large ribosomal subunit
large ribosomal subunit rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation
MPPKFDPNEV
MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN
cytoplasmic translation ribosomal large subunit assembly translation cytosol; cytosolic large ribosomal subunit large ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation MPPKFDPNEV MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN
cytoplasmic translation ribosomal large subunit assembly translation
cytosol; cytosolic large ribosomal subunit
large ribosomal subunit rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation
MPPKFDPNEV
MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN
cytoplasmic translation ribosomal large subunit assembly translation cytosol; cytosolic large ribosomal subunit large ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae Cytoplasm Direct protein sequencing Isopeptide bond Methylation Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding Ubl conjugation MPPKFDPNEV MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN
cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA export from nucleus
cytoplasm; cytosol; cytosolic small ribosomal subunit; mitochondrion; small ribosomal subunit
rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MSLVVQEQGS
MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA
cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA export from nucleus cytoplasm; cytosol; cytosolic small ribosomal subunit; mitochondrion; small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MSLVVQEQGS MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA
cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA export from nucleus
cytosol; cytosolic small ribosomal subunit; mitochondrion; small ribosomal subunit
rRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation
MSLVVQEQGS
MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA
cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA export from nucleus cytosol; cytosolic small ribosomal subunit; mitochondrion; small ribosomal subunit rRNA binding structural constituent of ribosome Saccharomyces cerevisiae Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MSLVVQEQGS MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA
asparagine catabolic process cellular response to nitrogen starvation
cell wall-bounded periplasmic space; extracellular region; periplasmic space
asparaginase activity
Saccharomyces cerevisiae
Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal
MRSLNTLLLS
MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation cell wall-bounded periplasmic space; extracellular region; periplasmic space asparaginase activity Saccharomyces cerevisiae Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal MRSLNTLLLS MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation
cell wall-bounded periplasmic space; extracellular region; periplasmic space
asparaginase activity
Saccharomyces cerevisiae
Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal
MRSLNTLLLS
MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation cell wall-bounded periplasmic space; extracellular region; periplasmic space asparaginase activity Saccharomyces cerevisiae Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal MRSLNTLLLS MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation
cell periphery; cell wall-bounded periplasmic space; extracellular region; periplasmic space
asparaginase activity
Saccharomyces cerevisiae
Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal
MRSLNTLLLS
MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation cell periphery; cell wall-bounded periplasmic space; extracellular region; periplasmic space asparaginase activity Saccharomyces cerevisiae Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal MRSLNTLLLS MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
detoxification of cadmium ion detoxification of copper ion removal of superoxide radicals response to copper ion
cytosol
antioxidant activity cadmium ion binding copper ion binding superoxide dismutase activity
Saccharomyces cerevisiae
3D-structure Copper Direct protein sequencing Isopeptide bond Metal-binding Metal-thiolate cluster Reference proteome Ubl conjugation
MFSELINFQN
MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKCPCGNKSEETKKSCCSGK
detoxification of cadmium ion detoxification of copper ion removal of superoxide radicals response to copper ion cytosol antioxidant activity cadmium ion binding copper ion binding superoxide dismutase activity Saccharomyces cerevisiae 3D-structure Copper Direct protein sequencing Isopeptide bond Metal-binding Metal-thiolate cluster Reference proteome Ubl conjugation MFSELINFQN MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKCPCGNKSEETKKSCCSGK
detoxification of cadmium ion detoxification of copper ion removal of superoxide radicals response to copper ion
cytosol
antioxidant activity cadmium ion binding copper ion binding superoxide dismutase activity
Saccharomyces cerevisiae
Copper Direct protein sequencing Isopeptide bond Metal-binding Metal-thiolate cluster Reference proteome Ubl conjugation
MFSELINFQN
MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKCPCGNKSEETKKSCCSGK
detoxification of cadmium ion detoxification of copper ion removal of superoxide radicals response to copper ion cytosol antioxidant activity cadmium ion binding copper ion binding superoxide dismutase activity Saccharomyces cerevisiae Copper Direct protein sequencing Isopeptide bond Metal-binding Metal-thiolate cluster Reference proteome Ubl conjugation MFSELINFQN MFSELINFQNEGHECQCQCGSCKNNEQCQKSCSCPTGCNSDDKCPCGNKSEETKKSCCSGK
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MANLRTQKRL
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MANLRTQKRL MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
cytoplasmic translation
cytosol; cytosolic large ribosomal subunit
RNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation
MANLRTQKRL
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
cytoplasmic translation cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation MANLRTQKRL MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor
mRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MAGVKAYELR
MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA
cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor mRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MAGVKAYELR MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA
cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor
mRNA binding structural constituent of ribosome
Saccharomyces cerevisiae
3D-structure Cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein
MAGVKAYELR
MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA
cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cytosol; cytosolic large ribosomal subunit; preribosome, large subunit precursor mRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein MAGVKAYELR MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA
positive regulation of mating-type specific transcription, DNA-templated regulation of mating-type specific transcription, DNA-templated regulation of transcription by RNA polymerase II
nucleus; RNA polymerase II transcription regulator complex
DNA binding, bending transcription coactivator activity
Saccharomyces cerevisiae
Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation
MFTSKPAFKI
MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIRPLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYSQFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGDGYWEDVFVHLAL
positive regulation of mating-type specific transcription, DNA-templated regulation of mating-type specific transcription, DNA-templated regulation of transcription by RNA polymerase II nucleus; RNA polymerase II transcription regulator complex DNA binding, bending transcription coactivator activity Saccharomyces cerevisiae Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation MFTSKPAFKI MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIRPLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYSQFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGDGYWEDVFVHLAL
negative regulation of transcription by RNA polymerase II regulation of mating-type specific transcription, DNA-templated regulation of transcription by RNA polymerase II
nucleus; RNA polymerase II transcription repressor complex
DNA binding, bending DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding
Saccharomyces cerevisiae
3D-structure Acetylation Direct protein sequencing DNA-binding Homeobox Nucleus Reference proteome Repressor Transcription Transcription regulation
MNKIPIKDLL
MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
negative regulation of transcription by RNA polymerase II regulation of mating-type specific transcription, DNA-templated regulation of transcription by RNA polymerase II nucleus; RNA polymerase II transcription repressor complex DNA binding, bending DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding Saccharomyces cerevisiae 3D-structure Acetylation Direct protein sequencing DNA-binding Homeobox Nucleus Reference proteome Repressor Transcription Transcription regulation MNKIPIKDLL MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
anatomical structure morphogenesis cell differentiation induction of conjugation with cellular fusion mating type determination positive regulation of induction of conjugation with cellular fusion positive regulation of meiotic cell cycle positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
cytoplasm; RNA polymerase II transcription regulator complex; spindle pole body
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending sequence-specific DNA binding, bending transcription coactivator activity
Schizosaccharomyces pombe
Cytoplasm Cytoskeleton DNA-binding Nucleus Reference proteome Stress response Transcription Transcription regulation
MDSHQELSAG
MDSHQELSAGSPISYDFLDPDWCFKRYLTKDALHSIETGKGAAYFVPDGFTPILIPNSQSYLLDGNSAQLPRPQPISFTLDQCKVPGYILKSLRKDTTSTERTPRPPNAFILYRKEKHATLLKSNPSINNSQVSKLVGEMWRNESKEVRMRYFKMSEFYKAQHQKMYPGYKYQPRKNKVKR
anatomical structure morphogenesis cell differentiation induction of conjugation with cellular fusion mating type determination positive regulation of induction of conjugation with cellular fusion positive regulation of meiotic cell cycle positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; RNA polymerase II transcription regulator complex; spindle pole body DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending sequence-specific DNA binding, bending transcription coactivator activity Schizosaccharomyces pombe Cytoplasm Cytoskeleton DNA-binding Nucleus Reference proteome Stress response Transcription Transcription regulation MDSHQELSAG MDSHQELSAGSPISYDFLDPDWCFKRYLTKDALHSIETGKGAAYFVPDGFTPILIPNSQSYLLDGNSAQLPRPQPISFTLDQCKVPGYILKSLRKDTTSTERTPRPPNAFILYRKEKHATLLKSNPSINNSQVSKLVGEMWRNESKEVRMRYFKMSEFYKAQHQKMYPGYKYQPRKNKVKR
proteolysis
extracellular region
aspartic-type endopeptidase activity metal ion binding
Candida albicans
Aspartyl protease Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen
MFLKNIFIAL
MFLKNIFIALAIALLVDASPAKRSPGFVTLDFDVIKTPVNATGQEGKVKRQAIPVTLNNELVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGSPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT
proteolysis extracellular region aspartic-type endopeptidase activity metal ion binding Candida albicans Aspartyl protease Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen MFLKNIFIAL MFLKNIFIALAIALLVDASPAKRSPGFVTLDFDVIKTPVNATGQEGKVKRQAIPVTLNNELVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGSPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT
adhesion of symbiont to host fungal-type cell wall organization induction by symbiont of defense-related host calcium ion flux induction by symbiont of host defense response induction by symbiont of host immune response nitrogen compound metabolic process protein catabolic process protein metabolic process proteolysis signal peptide processing transepithelial migration of symbiont in host
extracellular region; fungal-type cell wall
aspartic-type endopeptidase activity metal ion binding
Candida albicans
3D-structure Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Reference proteome Secreted Signal Virulence Zinc Zymogen
MFLKNIFIAL
MFLKNIFIALAIALLVDASPAKRSPGFVTLDFDVIKTPVNATGQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT
adhesion of symbiont to host fungal-type cell wall organization induction by symbiont of defense-related host calcium ion flux induction by symbiont of host defense response induction by symbiont of host immune response nitrogen compound metabolic process protein catabolic process protein metabolic process proteolysis signal peptide processing transepithelial migration of symbiont in host extracellular region; fungal-type cell wall aspartic-type endopeptidase activity metal ion binding Candida albicans 3D-structure Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Reference proteome Secreted Signal Virulence Zinc Zymogen MFLKNIFIAL MFLKNIFIALAIALLVDASPAKRSPGFVTLDFDVIKTPVNATGQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT
proteolysis
extracellular region
aspartic-type endopeptidase activity metal ion binding
Candida albicans
Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen
MFLKNIFIAL
MFLKNIFIALAIALLADATPTTFNNSPGFVALNFDVIKTHKNVTGPQGEINTNVNVKRQTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT
proteolysis extracellular region aspartic-type endopeptidase activity metal ion binding Candida albicans Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Metal-binding Protease Secreted Signal Virulence Zinc Zymogen MFLKNIFIAL MFLKNIFIALAIALLADATPTTFNNSPGFVALNFDVIKTHKNVTGPQGEINTNVNVKRQTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT
adhesion of symbiont to host fungal-type cell wall organization induction by symbiont of defense-related host calcium ion flux nitrogen compound metabolic process protein catabolic process protein metabolic process proteolysis signal peptide processing transepithelial migration of symbiont in host
extracellular region; extracellular vesicle; fungal-type cell wall
aspartic-type endopeptidase activity
Candida albicans
3D-structure Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Signal Virulence Zymogen
MFLKNIFIAL
MFLKNIFIALAIALLADATPTTFNNSPGFVALNFDVIKTHKNVTGPQGEINTNVNVKRQTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT
adhesion of symbiont to host fungal-type cell wall organization induction by symbiont of defense-related host calcium ion flux nitrogen compound metabolic process protein catabolic process protein metabolic process proteolysis signal peptide processing transepithelial migration of symbiont in host extracellular region; extracellular vesicle; fungal-type cell wall aspartic-type endopeptidase activity Candida albicans 3D-structure Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Signal Virulence Zymogen MFLKNIFIAL MFLKNIFIALAIALLADATPTTFNNSPGFVALNFDVIKTHKNVTGPQGEINTNVNVKRQTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTSDYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT
ascospore-type prospore assembly autophagy exocytosis Golgi to plasma membrane transport membrane addition at site of cytokinesis protein localization to plasma membrane protein secretion regulation of exocytosis vesicle docking involved in exocytosis vesicle fusion vesicle targeting
cellular bud tip; endosome; extracellular vesicle; incipient cellular bud site; mating projection tip; plasma membrane; spitzenkorper; transport vesicle membrane
GTP binding GTPase activity
Candida albicans
3D-structure Cell membrane Cytoplasmic vesicle Exocytosis GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport
MSGKGTSSRA
MSGKGTSSRAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNPSFITTIGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENIGGVGGASGAGGIDVSQNNSGAKNNCC
ascospore-type prospore assembly autophagy exocytosis Golgi to plasma membrane transport membrane addition at site of cytokinesis protein localization to plasma membrane protein secretion regulation of exocytosis vesicle docking involved in exocytosis vesicle fusion vesicle targeting cellular bud tip; endosome; extracellular vesicle; incipient cellular bud site; mating projection tip; plasma membrane; spitzenkorper; transport vesicle membrane GTP binding GTPase activity Candida albicans 3D-structure Cell membrane Cytoplasmic vesicle Exocytosis GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport MSGKGTSSRA MSGKGTSSRAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNPSFITTIGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENIGGVGGASGAGGIDVSQNNSGAKNNCC
conjugation with cellular fusion establishment or maintenance of cell polarity regulating cell shape positive regulation of mating projection assembly positive regulation of pheromone response MAPK cascade positive regulation of protein import into nucleus protein localization to plasma membrane signal transduction involved in positive regulation of conjugation with cellular fusion
cell cortex of cell tip; cortical dynamic polarity patch; division septum; mating projection actin fusion focus; plasma membrane
CTP binding G protein activity GDP binding GTP binding UTP binding
Candida albicans
Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation
MLREYKLVVV
MLREYKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRVKDSDNVPVLVVGNKCDLEMERQVSYEDGLALANSFNCPFLETSAKQRINVEEAFYGLVRNINQYNAKIAEAEKQQQQQQQQQNANQQGQDQYGQQKDNQQSQFNNQINNNNNTSAVNGGVSSDGIIDQNGNGGVSSGQANLPNQSQSQSQRQQQQQQQEPQQQSENQFSGQKQSSSKSKNGCCVIV
conjugation with cellular fusion establishment or maintenance of cell polarity regulating cell shape positive regulation of mating projection assembly positive regulation of pheromone response MAPK cascade positive regulation of protein import into nucleus protein localization to plasma membrane signal transduction involved in positive regulation of conjugation with cellular fusion cell cortex of cell tip; cortical dynamic polarity patch; division septum; mating projection actin fusion focus; plasma membrane CTP binding G protein activity GDP binding GTP binding UTP binding Candida albicans Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation MLREYKLVVV MLREYKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRVKDSDNVPVLVVGNKCDLEMERQVSYEDGLALANSFNCPFLETSAKQRINVEEAFYGLVRNINQYNAKIAEAEKQQQQQQQQQNANQQGQDQYGQQKDNQQSQFNNQINNNNNTSAVNGGVSSDGIIDQNGNGGVSSGQANLPNQSQSQSQRQQQQQQQEPQQQSENQFSGQKQSSSKSKNGCCVIV
asparagine catabolic process cellular response to nitrogen starvation
cell wall-bounded periplasmic space; endoplasmic reticulum; extracellular region; nuclear envelope; periplasmic space
asparaginase activity
Saccharomyces cerevisiae
Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal
MRSLNTLLLS
MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG
asparagine catabolic process cellular response to nitrogen starvation cell wall-bounded periplasmic space; endoplasmic reticulum; extracellular region; nuclear envelope; periplasmic space asparaginase activity Saccharomyces cerevisiae Direct protein sequencing Glycoprotein Hydrolase Periplasm Reference proteome Secreted Signal MRSLNTLLLS MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG