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Pharmacological targeting of cognitive impairment in depression: recent developments and challenges in human clinical research.
Impaired cognition is often overlooked in the clinical management of depression, despite its association with poor psychosocial functioning and reduced clinical engagement. There is an outsta... | 36,396,622 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.852147 | 0.805931 | BFU |
The Efficacy of Psychological Interventions on Health-Related Quality of Life for Patients With Heart Failure and Depression: A Systematic Review.
Depression is prevalent among adults with chronic heart failure (CHF) and is associated with higher rates of morbidity and mortality and higher healthcare costs. The aim of... | 33,394,624 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 8,489 | 7.255792 | -0.316911 | AdD/ |
Mindfulness-based cognitive therapy (MBCT) versus the health-enhancement program (HEP) for adults with treatment-resistant depression: a randomized control trial study protocol.
Major depressive disorder (MDD) is the leading cause of disability in the developed world, yet broadly effective treatments remain elusive. U... | 24,612,825 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.627667 | -0.413564 | CRGy |
Telephone and in-person cognitive behavioral therapy for major depression after traumatic brain injury: a randomized controlled trial.
Major depressive disorder (MDD) is prevalent after traumatic brain injury (TBI); however, there is a lack of evidence regarding effective treatment approaches. We conducted a choice-st... | 25,072,405 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 11,272 | 13.912336 | 4.853017 | CKkF |
Contemporary methods of improving cognitive dysfunction in clinical depression.
Cognitive dysfunction is prevalent in patients with major depressive disorder (MDD), with deficits observed across several domains (e.g., executive function, memory, attention). While depression alone is disabling, patients with cognitive ... | 31,020,872 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.891876 | 0.315366 | A7aM |
Psychological and pharmacological interventions for depression in patients with coronary artery disease.
Depression occurs frequently in individuals with coronary artery disease (CAD) and is associated with a poor prognosis. To determine the effects of psychological and pharmacological interventions for depression in ... | 34,910,821 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 16,172 | 7.164899 | 0.053192 | xmk |
Attention Bias Modification training in individuals with depressive symptoms: A randomized controlled trial.
Negative attentional biases are often considered to have a causal role in the onset and maintenance of depressive symptoms. This suggests that reduction of such biases may be a plausible strategy in the treatme... | 25,245,928 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.537033 | -0.257288 | CICK |
Positive online attentional training as a means of modifying attentional and interpretational biases among the clinically depressed: An experimental study using eye tracking.
The present study examined the effectiveness of online positive attention bias modification training (ABMT) in inducing positive attention and p... | 29,542,816 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 16.109045 | -0.088473 | BOmw |
Integrated traditional and Western medicine for treatment of depression based on syndrome differentiation: a meta-analysis of randomized controlled trials based on the Hamilton depression scale.
To systematically review the benefits of integrated traditional and Western medicine therapies based on the Hamilton depress... | 22,594,094 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 8,951 | 8.229069 | -0.229622 | CtZ7 |
Translational approaches in treatment-resistant depression based on animal model.
An intensively researched and yet poorly understood phenomenon, both at clinical and neurobiological level, is the determinism of treatment-resistant depression. Even more controversial are the stages of approaching therapeutically this ... | 30,534,840 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 5,984 | 9.741024 | -0.30389 | BCA2 |
Psychological and Psychosocial Interventions for Depression and Anxiety in Patients With Age-Related Macular Degeneration: A Systematic Review.
To review the current literature on psychosocial and psychological interventions to prevent and treat depression and anxiety in patients with age-related macular degeneration ... | 31,005,495 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,755 | 8.473115 | 1.858076 | A7nf |
Efficacy versus effectiveness: a direct comparison of the outcome of treatment for mild to moderate depression in randomized controlled trials and daily practice.
Results from randomized controlled trials (RCTs) are considered to give the most reliable information on treatment outcome (efficacy). Yet, the generalizabi... | 22,584,117 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,858 | 8.159556 | 0.864008 | CtiA |
A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Treatment-Resistant Depression.
Due to the clinical challenges of treatment-resistant depression (TRD), we evaluated the efficacy of mindfulness-based cognitive therapy (MBCT) relative to a structurally equivalent active comparison condition as a... | 26,808,973 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.576132 | -0.494948 | ByCN |
Cognitive bias modification as an add-on treatment in clinical depression: Results from a placebo-controlled, single-blinded randomized control trial.
Only 60% of depressed patients respond sufficiently to treatment, so there is a dire need for novel approaches to improve treatment effects. Cognitive Bias Modification... | 29,908,472 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.215292 | -0.4896 | BKSv |
Randomised controlled cognition trials in remitted patients with mood disorders published between 2015 and 2021: A systematic review by the International Society for Bipolar Disorders Targeting Cognition Task Force.
Cognitive impairments are an emerging treatment target in mood disorders, but currently there are no ev... | 35,174,594 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 6,095 | 12.93314 | 0.024909 | m2o |
A Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease (SPIRR-CAD): Results of an Observer-Blinded, Multicenter, Randomized Trial in Depressed Patients With Coronary Artery Disease.
Depression predicts adverse prognosis in patients with coronary artery disease (CAD), but previous treatment ... | 27,187,851 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,285 | 7.006779 | 0.145233 | BstS |
Cognitive training interventions and depression in mild cognitive impairment and dementia: a systematic review and meta-analysis of randomized controlled trials.
Depression is common in people with cognitive impairment but the effect of cognitive training in the reduction of depression is still uncertain. The purpose ... | 32,378,715 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 11,554 | 11.901243 | 4.418894 | Apft |
Longitudinal effects of cognitive behavioral therapy for depression on the neural correlates of emotion regulation.
Cognitive behavioral therapy (CBT) is effective for a substantial minority of patients suffering from major depressive disorder (MDD), but its mechanism of action at the neural level is not known. As cor... | 29,128,142 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,407 | 14.215919 | 0.67439 | BUTs |
Mindfulness-based cognitive therapy for the treatment of current depressive symptoms: a meta-analysis.
Mindfulness-based cognitive therapy (MBCT) appears to be a promising intervention for the prevention of relapse in major depressive disorder, but its efficacy in patients with current depressive symptoms is less clea... | 30,732,534 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.644793 | -0.473707 | A/OZ |
Cognitive remediation as a treatment for major depression: A rationale, review of evidence and recommendations for future research.
There is considerable literature regarding the effectiveness of cognitive remediation (CR) in schizophrenia and in conditions such as stroke and traumatic brain injury. Patients with majo... | 23,956,342 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.910178 | 0.378133 | CZ06 |
A cluster randomized controlled platform trial comparing group MEmory specificity training (MEST) to group psychoeducation and supportive counselling (PSC) in the treatment of recurrent depression.
Impaired ability to recall specific autobiographical memories is characteristic of depression, which when reversed, may h... | 29,587,159 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,732 | 14.350537 | -0.284506 | BOA7 |
Cognitive behavioral therapy for depression improves pain and perceived control in cardiac surgery patients.
Depression after cardiac surgery (CS) is associated with increased pain and decreased sleep quality. While cognitive behavioral therapy (CBT) aimed at depression is effective in relieving depressive symptoms af... | 26,115,954 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,940 | 6.477942 | -0.043318 | B7tX |
Feasibility and acceptability of group music therapy vs wait-list control for treatment of patients with long-term depression (the SYNCHRONY trial): study protocol for a randomised controlled trial.
Depression is of significant global concern. Despite a range of effective treatment options it is estimated that around ... | 28,356,125 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 17,830 | 10.377353 | 1.144886 | Bevr |
The generalizability of psychotherapy efficacy trials in major depressive disorder: an analysis of the influence of patient selection in efficacy trials on symptom outcome in daily practice.
Treatment guidelines for major depressive disorder (MDD) are based on results from randomized clinical trials, among others in p... | 23,137,143 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 8,564 | 9.681656 | -0.611894 | Cl+A |
The impact of executive function on response to cognitive behavioral therapy in late-life depression.
Late-life depression (LLD) is a common and debilitating condition among older adults. Cognitive behavioral therapy (CBT) has strong empirical support for the treatment of depression in all ages, including in LLD. In t... | 26,230,057 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 11.997995 | 0.963949 | B6HT |
Attentional bias modification in depression through gaze contingencies and regulatory control using a new eye-tracking intervention paradigm: study protocol for a placebo-controlled trial.
Attentional biases, namely difficulties both to disengage attention from negative information and to maintain it on positive infor... | 27,931,196 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.608438 | -0.002563 | BjpW |
Symptom severity moderates the outcome of attention bias modification for depression: An exploratory study.
A recent meta-analysis has questioned the relevance of attention bias modification (ABM) for depression outcomes. However, there might be patient characteristics not yet accounted for, that are relevant to the o... | 33,984,807 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.810696 | -0.32073 | AWZP |
Comparative effectiveness of non-pharmacological interventions for depressive symptoms in mild cognitive impairment: systematic review with network meta-analysis.
Depressive symptoms are common among mild cognitive impairment (MCI) patients. It is unknown how different the effects on depressive symptoms are among vari... | 34,841,997 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 14,383 | 8.708157 | -0.460598 | 0lE |
The Impact of One-Time Relaxation Training on Attention Efficiency Measured by Continuous Performance Test in Depressive Disorders.
Introduction: People with depression often complain of dysfunction in cognitive processes, particularly attention. Pharmacotherapy is one of the most commonly used methods of treating dep... | 35,682,056 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 15.565673 | -0.131843 | U3E |
Effects of reminiscence interventions on psychosocial outcomes: a meta-analysis.
This study integrated results from controlled trials of reminiscence interventions. Meta-analysis was used to aggregate results from 128 studies on 9 outcome VARIABLES. Compared to non-specific changes in control-group members, moderate i... | 22,304,736 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 14,606 | 10.593515 | 3.176441 | Cxzd |
The use of cognitive bias modification and imagery in the understanding and treatment of depression.
Cognitive models of depression form the natural link between neurobiological and social accounts of the illness. Interest in the role of cognition in depression has recently been stimulated by the advent of simple, com... | 22,566,082 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 14.69582 | -0.546253 | CtzW |
Intervention methods for improving reduced heart rate variability in patients with major depressive disorder: A systematic review and meta-analysis.
Several studies have demonstrated that patients with major depressive disorder (MDD) commonly show reductions in heart rate variability (HRV) parameters. Thus, interventi... | 36,183,449 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 12,837 | 11.406886 | 1.393928 | Fd0 |
Active versus receptive group music therapy for major depressive disorder-A pilot study.
To compare the effects of 1) active group music therapy and 2) receptive group music therapy to group counseling in treatment of major depressive disorder (MDD). On top of standard care, 14 MDD outpatients were randomly assigned t... | 27,261,995 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,698 | 10.347311 | -0.037782 | Br03 |
Computerized Memory Specificity Training (c-MeST) for major depression: A randomised controlled trial.
Given modest response and high relapse after treatment for Major Depressive Episodes (MDE), the development and refinement of treatments to target cognitive vulnerabilities is indicated. Memory Specificity Training (... | 33,291,054 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,732 | 14.237734 | -0.143671 | AeOV |
Cognitive Remediation for Outpatients With Recurrent Mood Disorders: A Feasibility Study.
Current first-line treatments for mood disorders often improve mood symptoms but do little to reduce cognitive and functional impairment. This 10-week, uncontrolled, feasibility study evaluated a cognitive remediation (CR) interv... | 32,692,124 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 6,095 | 13.36682 | -0.416995 | Alg6 |
Neurocognitive Remediation Therapy for Depression: A Feasibility Study and Randomized Controlled Pilot Protocol Testing.
Major depression is the most prevalent psychiatric disorder with high relapse rates. When mood can improve or fully recover, the neurocognitive difficulties associated with depression often persist,... | 26,153,888 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 13.167974 | -0.002311 | B7NW |
The effects of hypnotherapy compared to cognitive behavioral therapy in depression: a NIRS-study using an emotional gait paradigm.
Hypnotherapy (HT) is a promising approach to treating depression, but so far, no data are available on the neuronal mechanisms of functional reorganization after HT for depressed patients.... | 35,113,202 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 10,927 | 13.778342 | 0.611407 | pWo |
Cognitive Impairment Along the Course of Depression: Non-Pharmacological Treatment Options.
Major Depressive Disorder (MDD) is one of the most common psychiatric disorders, with a large global impact on both the individual and the society. In this narrative review, we summarize neurocognitive deficits during acute and... | 30,184,551 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.894101 | 0.22804 | BGkk |
Remission prognosis for cognitive therapy for recurrent depression using the pupil: utility and neural correlates.
Although up to 60% of people with major depressive disorder respond to cognitive therapy (CT) in controlled trials, clinicians do not routinely use standardized assessments to inform which patients should... | 21,447,417 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 16,413 | 13.213057 | -0.304894 | C+Hp |
[Reducing depressive symptoms in patients with dementia].
This comment is a reflection on the article 'Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis' of Jennifer Watt et al. (BMJ 2021;372:n532). Although 256 RCTs were incl... | 34,854,612 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 16,172 | 9.812448 | 3.553354 | 0Ag |
Leveraging CAM to treat depression and anxiety.
Conventional medications and psychotherapy are still first-line treatments, but certain complementary and alternative strategies have value as adjunctive measures. | 32,555,752 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 5,316 | 7.175084 | -0.109792 | AnOV |
Mindfulness-based cognitive therapy versus psychoeducational intervention in bipolar outpatients with sub-threshold depressive symptoms: a randomized controlled trial.
The presence of depressive subsyndromal symptoms (SS) in bipolar disorder (BD) increases the risk of affective relapse and worsens social, cognitive fu... | 25,124,510 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 10.25603 | -0.110385 | CJyw |
Personalized machine learning of depressed mood using wearables.
Depression is a multifaceted illness with large interindividual variability in clinical response to treatment. In the era of digital medicine and precision therapeutics, new personalized treatment approaches are warranted for depression. Here, we use a c... | 34,103,481 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,713 | 12.632483 | -0.331882 | AVA0 |
Short and long-term treatment outcomes of stepwise psychopharmacotherapy based on early clinical decision in patients with depressive disorders.
To investigate the effects of stepwise pharmacotherapy based on early clinical decision-making on short- and long-term treatment outcomes in outpatients with depressive disor... | 32,469,822 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,794 | 9.549711 | -0.521436 | AoSh |
Digital Therapeutics to Enhance Cognition in Major Depression: How Can We Make the Cognitive Gains Translate Into Functional Improvements?
| 35,775,161 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.771321 | -0.150214 | Rj4 |
Interpersonal and Social Rhythm Therapy for Patients With Major Depressive Disorder.
This study aimed to conduct a safety analysis among patients with major depressive disorder receiving interpersonal and social rhythm therapy (IPSRT) with and without cognitive remediation. This preliminary safety analysis of the outc... | 31,752,508 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,881 | 11.961492 | -0.401746 | AxfF |
Treat the brain and treat the periphery: toward a holistic approach to major depressive disorder.
The limited medication for major depressive disorder (MDD) against an ever-rising disease burden presents an urgent need for therapeutic innovations. During recent years, studies looking at the systems regulation of menta... | 25,849,660 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 5,528 | 10.005846 | -0.444332 | B/cw |
Depressive mood in adults with spinal cord injury as they transition from an inpatient to a community setting: secondary analyses from a clinical trial.
Prospective cohort controlled trial design. (i) To investigate mood benefits of adding group cognitive behaviour therapy (group-CBT) to standard spinal cord injury (S... | 28,462,933 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,322 | 6.834823 | 0.152142 | BdML |
Comparative efficacy and acceptability of traditional Chinese medicine for adult major depression: A protocol for network meta-analysis.
Major depression disorder (MDD) is a severe health threat characterized by persistent depression, loss of interests, lack of initiative, and even suicidal tendencies. Traditional Chi... | 33,217,832 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 14,383 | 8.387623 | 0.192649 | AfJQ |
Utilizing placebos to leverage effects of cognitive-behavioral therapy in patients with depression.
Patients with depression often experience difficulties with completing homework assignments during cognitive-behavioral therapy (CBT). In the present study, we investigated the effects of a specific placebo which aimed ... | 33,065,817 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,814 | 7.75764 | 1.467586 | Ag48 |
A Pilot, Randomized Controlled Study of Tai Chi With Passive and Active Controls in the Treatment of Depressed Chinese Americans.
This pilot, randomized clinical trial investigates the effectiveness of tai chi as the primary treatment for Chinese Americans with major depressive disorder (MDD). 67 Chinese Americans wit... | 28,570,792 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,596 | 8.316754 | 1.53989 | Bbwr |
Effectiveness of an Adjunctive Psychotherapeutic Intervention Developed for Enhancing the Placebo Effect of Antidepressants Used within an Inpatient-Treatment Program of Major Depression: A Pragmatic Parallel-Group, Randomized Controlled Trial.
| 32,069,467 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,814 | 8.495498 | 0.401386 | AtL0 |
The Current Evidence Levels for Biofeedback and Neurofeedback Interventions in Treating Depression: A Narrative Review.
This article is aimed at showing the current level of evidence for the usage of biofeedback and neurofeedback to treat depression along with a detailed review of the studies in the field and a discus... | 33,613,671 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 6,667 | 16.34462 | 4.605876 | Aafa |
Closed Loop Device May Alleviate Treatment-Resistant Depression.
| 34,751,728 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 8,212 | 9.903503 | -0.516503 | 4K8 |
Individual music therapy for depression: randomised controlled trial.
Music therapy has previously been found to be effective in the treatment of depression but the studies have been methodologically insufficient and lacking in clarity about the clinical model employed. Aims To determine the efficacy of music therapy ... | 21,474,494 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,698 | 10.242882 | 1.877148 | C9ua |
Pharmacotherapy for Depression Posttraumatic Brain Injury: A Meta-analysis.
To examine the effectiveness of pharmacotherapy for the treatment of depression following traumatic brain injury (TBI). Systematic review and meta-analysis. Multiple electronic databases were searched to identify relevant studies examining eff... | 26,479,398 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 11,272 | 13.921987 | 4.690445 | B2bG |
Longitudinal course of cognitive function across treatment in patients with MDD: A meta-analysis.
The longitudinal change of cognitive function across psychological treatment remains unclear. The aim of this meta-analysis was to synthesize results from longitudinal studies of cognitive deficits in MDD patients across ... | 30,753,954 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 13.023355 | 0.949965 | A+/F |
Effect of psychological interventions on depressive symptoms in long-term rehabilitation after an acquired brain injury: a systematic review and meta-analysis.
To summarize empirical studies on the effectiveness of psychological interventions in long-term rehabilitation after an acquired brain injury (ABI) in reducing... | 23,439,410 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 866 | 14.091391 | 4.904063 | ChbM |
Improving outcome for mental disorders by enhancing memory for treatment.
Patients exhibit poor memory for treatment. A novel Memory Support Intervention, derived from basic science in cognitive psychology and education, is tested with the goal of improving patient memory for treatment and treatment outcome. Adults wi... | 27,089,159 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,055 | 12.741705 | -0.350077 | BuEe |
Impact of pharmacological and psychological treatment methods of depressive and anxiety disorders on cognitive functioning.
Anxiety and depressive disorders are characterized by a number of clinical symptoms like decreased mood, apathy, anhedonia and anxiety. An important element of the clinical picture is also neuroc... | 25,078,256 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.636111 | -0.162224 | CKfZ |
Response to Individualized Homeopathic Treatment for Depression in Climacteric Women with History of Domestic Violence, Marital Dissatisfaction or Sexual Abuse: Results from the HOMDEP-MENOP Study.
Although individualized homeopathic treatment is effective for depression in climacteric women, there is a lack of well-d... | 29,871,025 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,846 | 7.519725 | -0.264925 | BKwr |
Establishing the dose of memory support to improve patient memory for treatment and treatment outcome.
Patient memory for the contents of treatment sessions is poor and this is associated with worse treatment outcome. Preliminary findings indicate that treatment provider use of memory support can be helpful in enhanci... | 31,733,608 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,055 | 12.736529 | -0.231305 | AxwD |
A randomized, controlled proof-of-concept trial evaluating durable effects of memory flexibility training (MemFlex) on autobiographical memory distortions and on relapse of recurrent major depressive disorder over 12 months.
Low-intensity psychological interventions that target cognitive risk factors for depressive re... | 33,691,266 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,732 | 13.736031 | -0.386464 | AZl/ |
Depressed patients treated by homeopaths: a randomised controlled trial using the "cohort multiple randomised controlled trial" (cmRCT) design.
Despite controversy regarding homeopathy, some patients consult homeopaths for depression. Evidence is required to determine whether this is an effective, acceptable and safe ... | 28,666,463 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 13,889 | 7.864701 | -0.492328 | BaY1 |
Cognitive Control Deficits in Depression: A Novel Target to Improve Suboptimal Outcomes in Childhood.
Cognitive control deficits are one of three primary endophenotypes in depression, and the enhanced targeting of these deficits in clinical and research work is expected to lead to improved depression outcomes. Cogniti... | 34,261,346 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 13.945781 | 0.007448 | ATP1 |
Performance benefits of depression: sequential decision making in a healthy sample and a clinically depressed sample.
Previous research reported conflicting results concerning the influence of depression on cognitive task performance. Whereas some studies reported that depression enhances performance, other studies re... | 21,500,878 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 14.609138 | 0.409995 | C9Tt |
Implementation of a manual-based training of humor abilities in patients with depression: a pilot study.
Humor and laughter can positively influence mood, promote optimism and lead to a change of perspective. Six patients with major depression participated in a group training program specifically designed to enhance h... | 21,071,099 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,015 | 10.39974 | 0.204687 | DDb5 |
Current Research on Complementary and Alternative Medicine (CAM) in the Treatment of Major Depressive Disorder: An Evidence-Based Review.
Complementary and alternative medicine (CAM) encompasses a wide range of different non-mainstream therapies that have been increasingly used for treatment or adjunctive treatment of... | 33,834,410 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,064 | 7.181572 | -0.095137 | AYE3 |
Cognitive behavioral therapy for post-stroke depression: A meta-analysis.
Cognitive behavioral therapy (CBT) has been widely used for post-stroke depression (PSD), but the findings have been inconsistent. This is a meta-analysis of randomized controlled trials (RCTs) of CBT for PSD. Both English (PubMed, PsycINFO, Emb... | 29,704,854 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 5,810 | 12.846291 | 5.628276 | BMiq |
Relaxation techniques for depressive disorders in adults: a systematic review and meta-analysis of randomised controlled trials.
Objectives: The aim of this study was to identify, evaluate, and synthesise existing randomised controlled trials (RCTs) that examined the effect of relaxation techniques in the treatment of... | 32,425,133 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 16,172 | 9.2219 | -0.54527 | Ao3f |
Relapse/Recurrence Prevention in Major Depressive Disorder: 26-Month Follow-Up of Mindfulness-Based Cognitive Therapy Versus an Active Control.
We conducted a 26-month follow-up of a previously reported 12-month study that compared mindfulness-based cognitive therapy (MBCT) to a rigorous active control condition (ACC)... | 30,146,148 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.756421 | -0.45169 | BHDK |
Psychological and pharmacological interventions for depression in patients with coronary artery disease.
Depression occurs frequently in patients with coronary artery disease (CAD) and is associated with a poor prognosis. To determine the effects of psychological and pharmacological interventions for depression in CAD... | 21,901,717 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,285 | 7.148544 | 0.251945 | C3sa |
Efficacy of a psychological online intervention for depression in people with epilepsy: a randomized controlled trial.
Depression is the most prevalent psychiatric disorder in persons with epilepsy (PWEs). Despite its major impact on quality of life and risk of suicide, most PWEs are not treated for depression. A curr... | 25,410,633 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,446 | 15.244058 | 9.894454 | CFyS |
Attentional bias modification reduces clinical depression and enhances attention toward happiness.
Difficulty in clinical antidepressant treatment leads to the pursuit of alternative treatments, such as cognitive-behavior therapy (CBT). CBT combined with regular antidepressants have indicated an optimal therapeutic ef... | 30,551,021 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.638465 | -0.040189 | BBzD |
Recovery from recurrent depression: Randomized controlled trial of the efficacy of mindfulness-based compassionate living compared with treatment-as-usual on depressive symptoms and its consolidation at longer term follow-up.
Mindfulness-Based Cognitive Therapy (MBCT) has been shown to reduce depressive symptoms in pa... | 32,421,612 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.65699 | -0.595124 | Ao61 |
Executive Functioning at Baseline Prospectively Predicts Depression Treatment Response.
Existing cognitive and clinical predictors of treatment response to date are not of sufficient strength to meaningfully impact treatment decision making and are not readily employed in clinical settings. This study investigated whe... | 28,196,313 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 9,099 | 12.749533 | 0.842862 | Bg0P |
Added value of Mindfulness-Based Cognitive Therapy for Depression: A Tree-based Qualitative Interaction Analysis.
To identify moderators of treatment effect for Mindfulness-Based Cognitive Therapy (MBCT) versus Treatment As Usual (TAU) in depressed patients. An individual patient data-analysis was performed on three r... | 31,557,693 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 9.387947 | -0.4091 | A0J+ |
Randomized trial of telephone versus in-person delivery of a brief psychosocial intervention in post-stroke depression.
A psychosocial behavioral intervention delivered in-person by advanced practice nurses has been shown effective in substantially reducing post-stroke depression (PSD). This follow-up trial compared t... | 29,017,589 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 5,810 | 12.618507 | 6.041636 | BVzS |
Talking bodies: nonverbal behavior in the assessment of depression severity.
Evaluations of clinical depression are traditionally based on verbal information. Nonverbal expressive behavior, however, being associated with a person's reflexive responses, may reveal negative emotional or social processes that are not und... | 23,706,840 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 21,572 | 15.054998 | -0.165243 | CdjY |
CBT and positive psychology interventions for clinical depression promote healthy attentional biases: An eye-tracking study.
Although there is a growing interest in the role of attentional biases in depression, there are no studies assessing changes in these biases after psychotherapeutic interventions. We used a vali... | 30,028,564 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,146 | 15.454741 | -0.142246 | BIsu |
Depression treated by homeopaths: a study protocol for a pragmatic cohort multiple randomised controlled trial.
The most commonly recommended treatments for depression are psychological/psychotherapeutic treatments, and antidepressant drugs. However, 38 percent of patients with depression do not use these recommended ... | 24,685,421 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 2,846 | 7.96805 | -0.526324 | CQAe |
Treatment of atypical depression: post-hoc analysis of a randomized controlled study testing the efficacy of sertraline and cognitive behavioural therapy in mildly depressed outpatients.
Atypical features are common among depressed primary care patients, but clinical trials testing the efficacy of psychopharmacologica... | 20,965,118 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,858 | 7.035833 | 2.000392 | DETk |
Autobiographical memory style and clinical outcomes following mindfulness-based cognitive therapy (MBCT): An individual patient data meta-analysis.
The ability to retrieve specific, single-incident autobiographical memories has been consistently posited as a predictor of recurrent depression. Elucidating the role of a... | 35,121,385 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 506 | 10.397568 | -0.000344 | pD8 |
Do distance-delivery group interventions improve depression in people with epilepsy?
About one-third of people with epilepsy experience comorbid depression. The present study examined outcomes of a distance-delivery group intervention program designed to improve emotional well-being. Participants were 55 adults with e... | 31,374,471 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,276 | 15.227162 | 9.475801 | A2mA |
Behavioral evidence for an impairment of affective theory of mind capabilities in chronic depression.
The only treatment specifically developed for chronic depression, the Cognitive Behavioral Analysis System of Psychotherapy (CBASP), is based amongst others on the hypothesis that chronically depressed patients (CD) s... | 26,278,924 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,821 | 14.206347 | -0.304166 | B5ai |
Better to give than to take? Interactive social decision-making in severe major depressive disorder.
Although recent studies focusing on major depressive disorder (MDD) suggest altered social decision-making, studies using the Ultimatum Game (UG) in patients with severe, clinical MDD do not exist. Moreover, all aforem... | 22,240,086 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 11,498 | 14.947345 | 0.353218 | Cyu4 |
Application of the Gradient Boosted method in randomised clinical trials: Participant variables that contribute to depression treatment efficacy of duloxetine, SSRIs or placebo.
Randomised, placebo-controlled trials of treatments for depression typically collect outcomes data but traditionally only analyse data to dem... | 25,080,392 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,679 | 10.22965 | -0.587225 | CKdh |
Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial.
To determine if hospitalized patients with depressive symptoms will benefit from post-discharge depression treatment with care transition support. This is a randomized controlled trial of hospitalized patients with patient heal... | 35,606,137 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 492 | 6.55223 | -8.377992 | Xco |
Exploring the impact of a complex intervention for women with depression in contexts of adversity: A pilot feasibility study of COURRAGE-plus in South Africa.
Depression is a leading cause of disease burden worldwide but is often undertreated in low- and middle-income countries. Reasons behind the treatment gap vary, ... | 33,855,902 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,436 | 8.786361 | -6.917415 | AX0X |
Positive strategies men regularly use to prevent and manage depression: a national survey of Australian men.
Men are at greater risk than women of dying by suicide. One in eight will experience depression--a leading contributor to suicide--in their lifetime and men often delay seeking treatment. Previous research has ... | 26,573,270 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 7,271 | 10.987864 | -6.998239 | B1G0 |
The methods and outcomes of cultural adaptations of psychological treatments for depressive disorders: a systematic review.
Cultural adaptations of evidence-based psychological treatments (PTs) are important to enhance their universal applicability. The aim of this study was to review systematically the literature on ... | 23,866,176 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,436 | 11.220774 | -7.219107 | CbOP |
Psychological treatments for depression and anxiety disorders in low- and middle- income countries: a meta-analysis.
The objective of this meta-analysis was to determine the efficacy of psychological treatments for depression and anxiety disorders in low- and middle- income countries (LAMIC). Meta-analysis of randomiz... | 21,863,204 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 17,770 | 9.968798 | -6.189517 | C4VM |
The feasibility, acceptability, and outcomes of PRIME-D: A novel mobile intervention treatment for depression.
Despite decades of research and development, depression has risen from the fifth to the leading cause of disability in the United States. Barriers to progress in the field are (1) poor access to high-quality ... | 28,419,621 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 1,427 | 7.234925 | -6.026404 | BdzY |
Effectiveness of psychological treatments for depression and alcohol use disorder delivered by community-based counsellors: two pragmatic randomised controlled trials within primary healthcare in Nepal.
Evidence shows benefits of psychological treatments in low-resource countries, yet few government health systems inc... | 30,678,744 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,436 | 9.500248 | -6.592337 | A/9z |
Discharge management strategies and post-discharge care interventions for depression - Systematic review and meta-analysis.
Patients with depression require treatment continuity when discharged from inpatient care. Interventions aimed at optimizing transition into outpatient care may be effective in preventing symptom... | 28,734,149 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 8,131 | 7.06031 | -8.476686 | BZa5 |
Patterns of practice in community mental health treatment of adult depression.
Community mental health therapists often endorse an eclectic orientation, but few studies reveal how therapists utilize elements of evidence-based psychotherapies. This study aimed to characterize treatment as usual patterns of practice amo... | 28,327,079 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 4,830 | 8.990246 | -6.378822 | BfJm |
The effect of depression and anxiety symptom severity on clinical outcomes and app use in digital mental health treatments: Meta-regression of three trials.
A large number of trials have consistently shown that guided digital mental health treatments (DMHTs) are effective for depression and anxiety. As DMHTs are adopt... | 34,600,398 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,446 | 7.697011 | -6.396502 | +Yw |
A therapist-guided smartphone app for major depression in young adults: A randomized clinical trial.
Meru Health Program (MHP) is a therapist-guided, 8-week intervention for depression delivered via smartphone. The aim was to test its efficacy in patients with clinical depression in a Finnish university student health... | 33,743,385 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 3,446 | 7.30701 | -6.169234 | AZGq |
Depression's moderation of the effectiveness of intensive case management with substance-dependent women on temporary assistance for needy families: outpatient substance use disorder treatment utilization and outcomes.
Intensive case management (ICM) is effective for facilitating entry into and retention in outpatient... | 21,388,603 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 14,973 | 7.178794 | -8.220061 | C++Y |
Reducing depressive symptoms through behavioral activation in churches: A Hybrid-2 randomized effectiveness-implementation design.
Rural African Americans are disproportionately exposed to numerous stressors such as poverty that place them at risk for experiencing elevated levels of depressive symptoms. Effective trea... | 29,170,075 | Major Depressive Disorder | Anxiety Treatment | Mental Health | 10,324 | 11.418641 | -6.249647 | BTuZ |
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