CID
int64
445
171M
canonical_smiles
stringlengths
5
1.4k
139,951,418
CC1OC(C)(C)C1CO
67,765,661
COCCNCc1cnc2nc(-c3cc(OCc4ccccc4)ccc3CC(C)C)[nH]c2c1
129,614,305
c1ccc(-n2nnnc2N2CCC(Cn3ccnc3)CC2)cc1
69,527,420
CCN(CCC1CC1)c1ccc2c(c1CCc1cc(C#N)cc(C(F)(F)F)c1)CCCC2
162,216,024
O=c1ccn(-c2ccccc2)c(CF)c1
163,788,482
CC(C)(C)c1ccc2c(c1)oc1cc(C(C)(C)C)ccc12.CC(C)(C)c1ccc2c(c1)oc1ccc(C(C)(C)C)cc12.CC(C)(C)c1ccc2c(c1)sc1cc(C(C)(C)C)ccc12.CC(C)(C)c1ccc2oc3ccc(C(C)(C)C)cc3c2c1.CC(C)(C)c1ccc2oc3cccc(C(C)(C)C)c3c2c1.CC(C)(C)c1ccc2sc3c(C(C)(C)C)cccc3c2c1.CC(C)(C)c1ccc2sc3cccc(C(C)(C)C)c3c2c1.CC(C)(C)c1cccc2c1-c1cccc(C(C)(C)C)c1C2(C)C.CC(C)...
169,834,215
C=CS[C@@H]1c2c(OC(C)=O)c(C)c3c(c2C(COC(=O)[C@@H]2NCCc4cc(OC(=O)N(C)CCN(C)C(=O)OCc5ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCC(=O)C(C)C)C(C)C)cc5)c(OC)cc42)N2[C@@H]1[C@H]1c4c(cc(C)c(OC)c4O)C4(C)C[C@@H]([C@@H]2O)N14)OCO3
161,635,808
CC(=O)N1CCC(C(=O)Nc2cccc3sc(Nc4ccccc4)nc23)CC1.CCC(=O)Nc1cccc2sc(Nc3ccccc3)nc12.O=C(Nc1cccc2sc(Nc3ccccc3)nc12)c1ccc2c(c1)OCO2.O=C(Nc1cccc2sc(Nc3ccccc3)nc12)c1ccccn1.O=C(Nc1cccc2sc(Nc3ccccc3)nc12)c1ccncc1
141,848,031
COCc1ccccc1N(C=O)C1CCN(C(=O)c2ccc(OC3CCNCC3C)cc2OC)CC1
160,422,652
C=C1[C@@H](C)N(C2CCCC2)c2nc(N3CCc4cc(C(=O)NC5CCN(C)CC5)ccc43)ccc2N1C.C=C1[C@@H](CC)N(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N1C.CC[C@@H]1C(=O)N(C)c2ccc(N3CCc4cc(C(=O)NC5CCN(C)CC5)ccc43)nc2N1C1CCCC1.CC[C@@H]1C(=O)N(C)c2cnc(N3CCOc4cc(C(=O)NC5CCN(C)CC5)ccc43)nc2N1C1CCCC1.CC[C@@H]1C(=O)N(C)c2cnc(N3CCc4cc(C(=O)NC5C...
140,238,158
O=C(O)C1CN(C(=O)O)CC1CF
89,242,122
COc1ccc(S(=O)(=O)N(C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)C(CC(N)=O)NC(=O)c2ccc3ccccc3n2)OC2CCCCC2)cc1
164,862,456
CCCC(NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)c1ccc2c(c1)OCO2
139,454,303
C=C(/N=C(/N=C(\C)c1ccc2c3c(cccc13)C1(c3ccccc3-c3ccccc31)c1ccccc1-2)c1ccc2c(c1)oc1ccccc12)c1ccccc1
171,040,176
CC([O-])=C(/N=N/c1cc(S(=O)(=O)Nc2ccccc2)ccc1O)C(=O)Nc1ccccc1.CC([O-])=C(/N=N/c1cc(S(=O)(=O)Nc2ccccc2C(=O)[O-])ccc1O)C(=O)Nc1ccccc1.[Co+3]
16,432,992
CC(C)CNS(=O)(=O)c1ccc(NC(=O)CN2CCCCCC2)cc1
3,946,415
Cc1c(NC(=O)COc2cccc(Br)c2)c(=O)n(-c2ccccc2)n1C
118,084,248
COc1ccc(Cl)cc1CCN1C(=O)c2ccc(Br)c(=O)n2CC1C
57,834,130
O=CCCc1cccc(-c2ccccc2)n1
164,755,426
CC(C)(C)c1ccc(-c2cc(-c3ccc(C(C)(C)C)cc3)cc(-c3cc(-c4cc(-c5ccc(C(C)(C)C)cc5)cc(-c5ccc(C(C)(C)C)cc5)c4)cc(C4(c5cc(-c6cc(-c7ccc(C(C)(C)C)cc7)cc(-c7ccc(C(C)(C)C)cc7)c6)cc(-c6cc(-c7ccc(C(C)(C)C)cc7)cc(-c7ccc(C(C)(C)C)cc7)c6)c5)c5ccccc5-c5c(-c6ccccc6-c6ccccc6)cccc54)c3)c2)cc1
59,400,107
Cn1ccc(S(=O)(=O)N2CC(Nc3nc(N)nc4[nH]ncc34)Cc3ccccc32)n1
57,832,527
COc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(C)CC3)CC2)cc(C)c1O
169,591,337
C=CCOc1ccc2occ(CC(=O)OCC)c2c1
159,565,142
CCc1ccc2c(c1)-c1cc(-c3cccc[n+]3C)c(C)cc1C2(C)C
153,394,322
C1=CC(c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c(-c6ccccc6)c(-c6ccccc6)c6ccccc6c45)c3)n2)=CCC1
134,217,293
C1=CC2C(c3ccccc3N2c2cc(-n3c4ccccc4c4c5oc6ccccc6c5ccc43)ccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c2oc3ccccc3c21
145,675,502
CC(C)(C)NSc1ccc(-c2oc(C(=O)NC34CCC(C(=O)O)(CC3)C4)nc2CC2CCCCC2)c2ccccc12
161,806,717
CCCC[N+](C)(C)CCOC(C)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)COC(C)COCCN(CC)c1cccc(C)c1
87,057,894
N/C=C/Cc1cnc[nH]1
97,947,534
Cc1c(-c2ccc(Cl)cc2Cl)nc2ccccc2c1C(=O)NC[C@@]1(C)C[C@H](NC(=O)c2c(C)c(-c3ccc(Cl)cc3Cl)nc3ccccc23)CC(C)(C)C1
71,213,792
CCC1OC(O)(C(=O)O)CC(O)C1NCO
24,813,411
Cc1ccc(-c2nn(-c3ccccc3)cc2-c2oc3ccccc3c(=O)c2O)cc1
21,043,287
CCCC(=O)N(CCS)CC(=O)Nc1ccccc1S
90,252,322
C[C@H]1C[C@@H](c2ccncc2Nc2ncc3ccc(-c4c(F)cc(C5CC5)cc4F)nn23)C[C@@H](N)[C@]1(C)O
88,401,129
C=CCCC1COC(c2ccc(-c3ccc(-c4ccc(C5CO5)c(F)c4F)cc3)c(F)c2F)OC1
141,977,345
CC.CC.CC(C)(O)CCNC1NC=C(/C=C/C2NC=C(C(C)(C)C)O2)S1
71,321,941
N#CC(=CNC(N)=O)C(=O)O
131,992,057
CCN(c1ccccc1)C(O)c1nn(C2CCN(C)CC2)c(=O)c2c1c1ccccc1n2C
1,432,636
Cc1cccc(C)c1NC(=O)[C@@H](C)Sc1nnc(-c2ccncc2)n1CCc1ccccc1
58,361,492
C=[N+]([O-])c1cc2oc3ccccc3c2cc1C(C)C
71,903,217
Cc1ccc(S(=O)(=O)N(C)CC(=O)Nc2c(C)cccc2C)c(C)c1
1,137,083
COc1ccccc1NC(=S)N(Cc1ccc(F)cc1)Cc1cc2cc(C)c(C)cc2[nH]c1=O
20,073,209
CCCCCCCCCCCCC#CC(CCCCC(=O)O)SCCNC(=O)C(F)(F)F
89,915,118
CC1CCCN1C(=O)c1nn(C)cc1C(N)=O
71,048,986
COC1CN(C(=O)C2=CCC(Oc3cc(O[C@@H](C)CO)cc(C(N)=O)c3)C=C2)C1
160,662,193
c1ccc(-c2ccc(-n3c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cccc(-c6ccccc6)c5)cc4c4c5c(ccc43)C(c3ccccc3)(c3ccccc3)c3ccccc3-5)cc2)cc1.c1ccc(-c2ccc(-n3c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cccc(-c6ccccc6)c5)cc4c4ccc5c(c43)C(c3ccccc3)(c3ccccc3)c3ccccc3-5)cc2)cc1
3,130,452
COc1cc(C=C2C(=O)OC3(CCCCC3)OC2=O)ccc1OCc1ccccc1
58,987,962
C#Cc1cc(C[C@@H](NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CC4CCC(C3)N4C)CC2)cc(Cl)c1N
70,432,739
COC(=O)/C(=C\c1ccccc1C(F)(F)F)C(C)=O
143,968,107
CCCCCCCCOC(=O)/C(=C/C=C/N(CCOCCN(/C=C/C=C(/C(=O)OC)S(=O)(=O)c1ccccc1)Cc1ccccc1)Cc1ccccc1)S(=O)(=O)c1ccccc1
59,656,361
O=C(Nc1ccc(S(=O)(=O)NC2CCN(Cc3ccccc3)CC2)c2ccccc12)c1ccccc1
88,999,782
C=C(O)c1ccc(N)c(O)c1
139,354,214
[H]/N=N/S(=O)(=O)OCC1C[C@@H](Nc2ncncc2C(=O)c2cc(Cc3cccc(C)c3)co2)C[C@@H]1O
100,439,465
CC[C@@H](C(=O)NC1CCCC1)N(Cc1cccc(OC)c1)C(=O)Cc1ccc(Cl)cc1Cl
51,033,678
Cc1cccc(C)c1N1CC(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(C(C)O)CC1=O
16,045,873
CC(C)CN(NC(=O)c1ccc(CN2CCN(CCCN(C)C)CC2)cc1)c1nc(C#N)ncc1Cl
67,124,394
N#Cc1c(N)ncnc1NCCc1nc2ccc(F)cc2cc1C(=O)NCC1CC1
139,691,866
[H]/N=c1\c(C#N)c(SC)c(C(=O)c2ccc(F)cc2)c2scc(C)n12
140,094,049
COCC1C2CCC1C(C(O)C(Cc1ccccc1)N(Cl)C(C)=O)N2
165,166,222
CC(C)c1cc(F)cc(Oc2c(Cl)ccc(CNC(=O)C3CCN(S(N)(=O)=O)CC3)c2Cl)c1
159,380,161
Fc1ccccc1Cn1nc(-c2ncc(F)c(Cl)n2)cc1-c1ccon1.O=C(COc1nc(-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)ncc1F)N1CCOCC1
139,332,253
O=C(O)c1cn(Cc2cc(F)c3ncc(Cl)cc3c2)nc1CO
41,167,729
C[C@@H]1Oc2c(C(=O)N3CCN(c4cnn(-c5ccccc5)c(=O)c4Cl)CC3)cccc2[C@@H]1C
14,140,171
Cn1nc([N+](=O)[O-])c2cccnc21
13,821,518
CSCC[C@H]1NC(=O)[C@@H]([C@@H](C)c2cn(C)c3ccccc23)NC1=O
88,551,458
c1c2c(cc3nsnc13)N=S=N2
50,803,105
Cc1cccc(-c2nn3c(=O)cc(CN4CCN(C(=O)COc5ccccc5)CC4)nc3s2)c1
117,632,215
O=S(=O)(Nc1nc(Cl)cc(-c2ccccc2F)n1)C1CC1
7,532,951
COc1ccc(-c2csc(NC(=O)c3cccc(OC)c3OC)n2)cc1C
2,178,287
COc1ccc(OCCNS(=O)(=O)c2ccc(F)cc2)cc1
126,022,680
Cc1cc(/C=C2/NC(=O)N(Cc3ccc(F)cc3)C2=O)c(C)n1-c1ccc(N(C)C)cc1
87,747,712
NC1=CC(C(F)(F)F)(C(F)(F)F)/C(=C2\C=CC(N)=CC2(C(F)(F)F)C(F)(F)F)C=C1.Nc1ccc(-c2ccc(N)cc2)cc1
156,161,133
C#CCOCCOCCOCCOCCOCCCCn1c(CN2C(=O)C3(CNC3)c3ccncc32)nc2cc(Cl)ccc21
20,310,460
N#Cc1ccc(NC(=S)N(Cc2ccccc2)Cc2ccccn2)cc1
58,059,718
CC(C)C(=[N+]=[N-])C(C)C
7,208,152
COc1cccc2sc(N(CCN(C)C)C(=O)c3nc4ccccc4s3)nc12
124,157,794
CC(C)(O)C(F)CNC(=O)c1cnc(-c2cnn3cc(Cl)cnc23)cc1NC1CC1
125,724,048
O=C([C@@H]1CCCN(S(=O)(=O)Cc2ccc(Cl)c(Cl)c2)C1)N1CCN(C/C=C/c2ccccc2)CC1
169,279,685
Cc1c2ccccc2n2c3c4c5c(c6c7ccccc7n(-c7ccccc7)c63)Oc3cccc6c3B5c3c-6cccc3-n4c12
121,366,102
CC(C)Oc1ccccc1-c1oc2ccc(N)cc2c(=O)c1O
163,554,402
Nc1cc2c(cc1NO)CCC2N=O
53,478,815
CCCCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O[C@H](COC(=O)CCCC/C=C\C/C=C\C/C=C\CCCCC)COP(=O)([O-])OCC[N+](C)(C)C
4,251,196
Cc1[nH]n(-c2ccc(Cl)cc2)c(=O)c1/C=N/c1ccc(S(=O)(=O)Nc2ccccc2Br)cc1
144,591,956
CC1=CC(C)C(c2ccc(C)cc2C)C(C)=C1
58,190,187
CCOc1ccc(-c2ccc(CC(=O)CCc3cc(F)cc(OCCN4CCCCC4)c3)nc2)cc1
140,862,115
Nc1c(C(=O)Nc2ccc(Cl)cc2)cnn1-c1cccc(Cl)c1Cl
158,601,554
Cc1cc[nH]c1C.[Ru]
142,541,233
CCC(Cc1ccc(Oc2ccnc3c2cc(C)n3COCC[Si](C)(C)C)cc1)C(=O)O
2,056,224
c1ccc(CN2CCN(Cc3cccnc3)CC2)cc1
155,090,973
COc1cc(C(=O)O)nc2ccc(N3CCC(C=Cc4c(-c5c(Cl)cncc5Cl)noc4C4CC4)CC3)cc12
84,039,774
O=CC1CCCc2ccc(Cl)cc21
20,378,614
O=C(Cl)Cc1csc(NC(=O)OCC(Cl)(Cl)Cl)n1
46,925,381
CCCCc1ccc(NC(=O)Cn2c(=O)n(Cc3cccc(Cl)c3)c(=O)c3ccccc32)cc1
153,780,207
CN1CCNC2=CC=CCC21
118,875,020
CN1C(=O)c2c(n[nH]c2Cl)N2CC(C)(C)N=C12
89,299,464
C=CNC(=O)C(N)=C(N)N
139,565,160
C=C(/C=C\C1=C(C)C2(CCOCC2)c2[nH]c3cc(Br)ccc3c2C1=O)OC
143,303,984
C#CCCCNC(=O)OC(C)(C)C.CCC
118,553,193
CC(C)(C)OC(=O)N1CCc2c(sc3ncnc(Nc4cc5cn[nH]c5cn4)c23)C1
155,052,857
C=C1N=C2C=CC(c3ccc4cc(-c5ccc(-c6ccc(C7=CCNC=C7)cc6)c(C(C)(c6ccccc6)c6ccccc6)c5)ccc4c3)=CN2Oc2ccccc21