CID
int64
445
171M
canonical_smiles
stringlengths
5
1.4k
129,519,832
CCOC(=O)N[C@@H]1CS(=O)(=O)C[C@@H]1NS(=O)(=O)c1cc(C(=O)O)ccc1C
7,589,577
CCOC(=O)CCNC(=O)N1CCn2cccc2[C@H]1c1ccc(Cl)cc1
135,738,812
C[C@H]1CCc2c(sc3ncn([C@@H](C)C(=O)/N=N/c4c(O)n(C)c5ccccc45)c(=O)c23)C1
89,562,001
COc1cc2c(cc1OCC(F)(F)F)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C)cc1)C(=O)C2
167,709,007
CCCCCCOC(=O)CC(CC)C(=O)C(C)(C)CC(CC(=O)C(C)(C)CC(CC(=O)NCCNCCN)C(=O)NCCCC)C(=O)NCCNCCN.CCCCNC(=O)C(CC(=O)NCCNCCN)CC(C)(C)C(=O)CC(CC(C)(C)C(=O)C(CC)CC(=O)CCCC)C(=O)NCCNCCN.CCCCNC(=O)C(CC(=O)NCCNCCN)CC(C)(C)C(=O)CC(CC(C)(C)C(=O)C(CC)CCCC)C(=O)NCCNCCN
157,594,838
c1ccc(N(c2cccc(-c3ccc(-c4ccc5c(c4)oc4ccccc45)cc3-c3ccc4c(c3)oc3ccccc34)c2)c2ccc3ccccc3c2)cc1.c1ccc(N(c2cccc(-c3ccc(-c4ccc5c(c4)oc4ccccc45)cc3-c3ccc4c(c3)oc3ccccc34)c2)c2ccc3ccccc3c2)cc1.c1ccc(N(c2ccccc2)c2cccc(-c3ccc(-c4ccc5c(c4)oc4ccccc45)cc3-c3ccc4c(c3)oc3ccccc34)c2)cc1
122,515,674
COc1cccc(N[C@@H]2C(=O)N(c3ccc(-c4cn[nH]c4)cc3)C[C@H]2CO)c1
68,423,978
C=CCN1CC(=O)C2C(Cc3ccc(O)cc3)C(=O)N(Cc3cccnc3N3CCC(N4CCCC4)CC3)CC2N1C(=O)NCc1ccccc1
139,452,289
CN=S(=O)(Cc1ccccc1F)C(C)(C)/C(N)=N\CF
86,792,732
CN(C(=O)c1ccn(C)c(=O)c1)c1nc2ccccc2n1C
97,483,509
c1ccc(C[C@H]2CNCC[C@@H]2OCc2cccnc2)cc1
137,491,459
O=C(COc1ccc(Cl)c(F)c1)NC12CC([C@@H]3CN(CC4CCC4)C(=O)O3)(C1)C2
142,152,446
Oc1ccccc1.POc1ccccc1
164,952,225
CC(=O)C[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@@](Oc2ccc3c(c2)Oc2cc(NCC(F)(F)F)ccc2C32OCc3ccccc32)(C(=O)O)C[C@@H]1O
13,251,615
O=C(NC(=O)c1cc(F)ccc1Cl)Nc1ccc(Cl)c(Cl)c1
92,236,788
CC(=O)Oc1cccc2c1CC[C@H]1C[C@@H](OC(C)=O)CC[C@@H]21
72,115,974
Cc1ccc(N2CCOC2=O)cc1NC(=O)c1ccc(Cl)s1
1,798,071
CCCCc1ccc(-n2nc3ccc(NC(=S)NC(=O)c4ccc5ccccc5c4)cc3n2)cc1
68,627,024
C=CCn1cc2ncnc(CCCCC)c2n1
88,247,185
CCCC1OC2=C(O1)[C@@]1(C)C(=CC2=O)[C@@H](F)C[C@H]2[C@@H]3CC[C@@H](C(=O)SC)[C@@]3(C)C[C@H](O)[C@@]21F
69,949,318
Cc1cc(C2CCN(S(=O)(=O)C3(C(=O)O)CCN(Cc4ccccc4)C(C)C3)CC2)ccc1Br
100,505,993
Cc1cc(N2C(=S)N[C@H](c3ccccn3)[C@@H]2c2cc(C)n(C(C)C)c2C)ccc1Br
25,077,438
NC(N)=NCCC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)O
58,697,708
COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)CS
91,091,176
Cc1ccc(N(C(=O)c2ccc(F)cc2)C2CCN(C3CCCCC3=O)CC2)cc1
7,962,593
COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)[C@@H]1c1ccc(Cl)cc1Cl
124,586,927
O=[N+]([O-])c1ccc(COc2c(I)cc(/C=N\Nc3nc4ccccc4s3)cc2I)cc1
57,000,943
CC(O)C(=O)c1cccc(C#N)c1
49,769,739
O=c1cc(-c2cccc(-c3cccc(CNCc4ccccc4)c3)c2)c2cccnc2n1O
20,037,682
CC(=O)SCC(C)C(=O)NN1CCN(C(C)=O)CC1.c1ccccc1
140,637,178
CC(C)(C)OC(=O)C[C@@H]1C/C=C\C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O[C@H](c2ccccc2)CNC1=O
124,292,018
CC(C)(C(=O)N1CCCCO1)C(F)F
89,198,604
CCC(C)(COC(C)COCC1CO1)N1C(=O)c2ccccc2C1=O
168,726,537
COc1cc(C(=O)O)c(F)cc1NS(=O)(=O)c1csc(C#Cc2ccc(C)cc2)n1
143,570,027
CC.CC(C)n1c(/C=C/C2CC(CC(=O)OC(C)(C)C)OC(C)(C)O2)c(-c2ccc(P)cc2)c2ccccc21
91,793,871
Cc1nc2ccccn2c1CC(=O)N[C@@H]1COCC[C@@H]1OCC(=O)O
89,578,750
Cc1cc2c(-c3ccc(-c4ccccc4)c4ccccc34)c3sc(C)cc3c(-c3ccc4ccccc4c3)c2s1
59,145,603
CC(C)COC(C)ONC(=O)/C=C/c1ccc(O)cc1
14,324,636
CCC(Cl)CC(C)CCCO
158,532,168
Cc1ccc(S(=O)(=O)Cc2ccc(CC(C)C)cc2)cc1
87,211,476
Cc1ccc(-c2ccc(/C=N/N(c3ccccc3)c3ccccc3)c(Nc3ccccc3)c2)cc1
169,127,898
CC#N.COc1nc(N2CCN(C(=O)/C=C/CN3CCOCC3)CC2)c2cnc(-c3nc(N)cc4cccc(Cl)c34)c(F)c2n1.FC1CC2CCCN2C1
51,729,165
C[C@@H](NC(=O)N(C)Cc1ccccc1Cl)c1ccc(-n2ccnc2)cc1
67,477,817
COc1ccc(CCN2C(=O)/C(=C\c3ccc4c(c3)c3ccccc3n4-c3ccccc3)O/C2=N\c2ccccc2C)cc1
166,468,472
C[C@H](Cc1ccc2c(c1)OCO2)N(C)C(=O)OCCN1CCCCC12COC2
142,270,766
C.CC.COc1cccc(C(CCN)C(=O)Nc2ccc3c(c2)C(C)NC3)c1.Cc1cccc(Cl)c1
167,142,232
CCC1C(N)C2CC(CC(C)C3C4CCC(C4)C3N)C1C2
126,135,309
Cc1cccc(C(=O)N[C@@H](C)c2nnc(SCC(=O)Nc3ncccc3C)n2C)c1
69,577,818
CCc1cccc(C(CCc2cccs2)C(=O)NN)c1CC
100,453,844
CCCNC(=O)[C@H](C)N(Cc1ccccc1)C(=O)CN(c1cccc2ccccc12)S(C)(=O)=O
24,232,778
CCn1c(=O)c(C(=O)COc2ccc(F)cc2Br)c(N)n(Cc2ccccc2)c1=O
139,989,333
CC(C)OC(=O)CC(Oc1ccccc1)C(=O)OC(C)C
88,055,486
COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](OC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)[C@@H]2NC(=O)C(C)(C)OC(=O)N[C@@H](Cc2ccccc2)C(=O)O)(c2ccccc2)c2ccc(OC)cc2)cc1
71,406,860
CCC(=O)Nc1cccc(-c2cc(-c3cccc(NC(=O)CC)n3)nc(N)n2)n1
158,695,925
c1ccc(N(c2ccccc2)c2ccc(-c3cc(-c4ccc5c(c4)c4cc6ccccc6cc4n5-c4ccccc4)cc(-c4ccc5c(c4)c4cc6ccccc6cc4n5-c4ccccc4)c3)cc2)cc1.c1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4cc(-c5ccc6c(c5)c5cc7ccccc7cc5n6-c5ccccc5)cc(-c5ccc6c(c5)c5cc7ccccc7cc5n6-c5ccccc5)c4)cc3)cc2)cc1
156,405,466
CC(C)CS(=O)(=O)c1ccccc1Oc1ccc(-c2noc(CN3C(=O)N(CCN4CCOCC4)C4(CCN(C(=O)CCC(=O)O)CC4)C3=O)n2)cc1C(F)(F)F
69,877,266
COc1ccc(-n2c(-c3ccc(S(C)(=O)=O)c(F)c3)coc2=O)cc1Cl
130,405,868
O=C1CN(C(=O)c2c(F)cccc2F)C(c2ccc(Cl)c(C(F)(F)F)c2)N1O
139,825,816
CCOC(=O)C(C)CN(C)C(=O)CCC(=O)O
162,177,230
CC1(C)c2ccccc2-c2c1cc1c3cccc4c3c3c(cccc3n3c5ccccc5c2c13)n4-c1nc2ccc3ccccc3c2nc1-c1ccccc1.CC1(C)c2ccccc2-c2c1cc1c3ccccc3n3c4cccc5c4c4c(cccc4n5-c4nc5ccc6ccccc6c5nc4-c4ccccc4)c2c13.CC1(C)c2ccccc2-c2cc3c4ccccc4n4c5cccc6c5c5c(cccc5n6-c5nc6ccc7ccccc7c6nc5-c5ccccc5)c(c21)c34
139,618,789
COC(c1ccccc1)N1CCC(CCC(CN(C)C(=O)Cc2cccc(Cl)c2)c2ccc(Cl)c(Cl)c2)CC1
142,034,406
CC.CCC(=O)C1=C(OC)CC(C(=O)O)CC1=O
171,097,968
C/N=C(C#N)/C(=C\N)c1cc2c(cc1-c1ccc(F)cc1F)C(=O)NC2
7,312,690
CC1=C(/C=C/[C@@H](C)O)C(C)(C)CCC1
141,043,723
COc1ccc2[nH]c(-c3cc(Br)ccc3CC=O)cc2c1
67,575,400
CC(=O)N1Cc2cccc(F)c2C1
53,870,030
CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](N(C)C)[C@@H]1OC(C)=O
67,404,207
CC1(C)CC1(C)C.Cc1cc([N+]2(N3CCC[C@@H]3C)CCCC2)ccc1NC(=O)O
158,820,787
C.CCCC(NC(=O)C(C)Cc1c[nH]c2ccccc12)C(=O)OC(c1ccccc1)(c1ccc(C)cc1)c1ccccc1Cl.CCCC(NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)OC(c1ccccc1)(c1ccc(C)cc1)c1ccccc1Cl.[H][H]
96,408,133
c1cnc(OC2CCN([C@@H]3CCOC4(CCOCC4)C3)CC2)nc1
22,611,895
O=C(O)CCNC(=O)CC1CCCN(C(=O)CC2CCNCC2)C1
89,578,831
N#CCc1c[nH]c2ccc(CO)cc12
132,242,990
CN(CCO)C1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2CC(NC(=O)c2cc(C4CC4)on2)C3)CC1
91,603,183
Cc1ccc(S(=O)(=O)OC[C@H]2C[C@@H](OS(=O)(=O)c3ccc(C)cc3)CN2C(=O)OC(C)(C)C)cc1
54,425,656
CCCCCCC(C(=O)OC)c1ccc(Cc2ccccc2C(=O)OCC)cc1
140,144,127
CC(C)c1ccc2c(c1Cl)C(=O)N(C)C[C@H]1[C@](C)(C(=O)O)CCC[C@]21C
145,608,290
CN1CCC(c2c(O)cc(O)c3c(=O)cc([Al])oc23)[C@@H]1CO
166,920,970
CCCC(C=O)N1Cc2c(SCCCCCCCNC(CN)C3CCCC3)cccc2C1=O
135,228,385
CNC1CSCc2cc3cc(c2)CSCC(NC(=O)C(C)NC(=O)C(Cc2cccc4ccccc24)NC(=O)C(CCC(=O)O)NC(=O)NC(=O)C(C)N1)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(=O)O)C(=O)NC(C(C)(C)C)C(=O)NC(C(N)=O)CSC3
87,929,805
Nc1cc(-c2ccncc2)nn1CC=O
145,555,684
CCCO.CC[C@@H](C[S+]([O-])C(C)(C)C)N1C(=O)COCC1c1ccc(Cl)cc1.Clc1ccccc1
140,879,179
CCC1CCC(CN2C(=O)CC3Cc4ccc(B5OC(C)(C)C(C)(C)O5)cc4C32)CC1
167,093,912
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C(NC(=O)COCCOCCN(C)C(=O)CCCc2ccc(N3C(=S)N(c4ccc(C#N)c(C(F)(F)F)c4)C(=O)C3(C)C)cc2)C(C)(C)C)cc1
153,730,691
COc1ccccc1C/N=C(\N)N=C1NC(=C2CCCCN2)CS1
53,505,956
NS(=O)(=O)NCCc1ccc2c(c1)OCO2
54,282,052
CCCc1c(OCCCCCOc2cccc(OCCCCC(=O)OCC)c2CCC(=O)OC)ccc2c1OCCC2=O
117,745,545
C=CCNC(=O)C(=O)C(CCCC)NC(=O)[C@@H]1CC(C)(C)C(C)CN1C(=O)[C@@H](NC(=O)NC1(CS(=O)(=O)C(C)(C)C)CCCCC1)C1(C)CCCC1
154,131,068
CCOC(=O)C=C(C)SCC(C)CCCC(C)C
139,557,985
COc1ccc(-c2nnc(SCCCC(=O)O)o2)c(Cl)c1
70,103,036
Nc1nccn1-c1ccc(Cl)cc1C(=O)c1ccccc1
16,132,180
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)O
140,046,988
Cc1ccccc1CN[C@@H](c1ccccc1)[C@@H](NCc1ccccc1C)c1ccccc1
16,061,960
COc1ccccc1CNc1cc(N2CCN(C)CC2)nc(N)n1
158,082,695
CN.CNCC(O)CNC.OC(CCl)CCl
19,426,961
COC(=O)c1cccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1
1,758,125
Cc1oc2cc3oc(=O)c(CC(=O)NCCCC(=O)O)c(C)c3cc2c1C
118,021,287
O=C(O)N1CCc2cnc(NC3CCC(O)CC3)nc2C1
166,131,136
COC(=O)c1cc(-c2ccc(C(=O)N3Cc4ccc(C#N)cc4C3)cn2)ccc1N(CC1CC1)C(C)=O
11,713,102
CC(C)(C)CN(CC(=O)Nc1ccc(-n2ccnc2)cc1)c1ccnc(C#N)n1
68,192,380
CCNc1ncc(-c2ccc(CC(C)NC(=O)C3CC3)cc2)cn1