CID
int64
445
171M
canonical_smiles
stringlengths
5
1.4k
647,456
O=C(CSc1nnnn1C1CCCC1)Nc1ccc2c(c1)OCO2
149,422,306
Cn1ccc(-c2ccc(Cc3cc(C(=O)N[C@H]4CCCC[C@@H]4O)nc(-n4cccn4)c3)cc2)n1
69,667,738
C=Cc1ccc(-c2[nH]c3c(c2C)C(=O)NCC3)cc1
140,480,137
Cc1cn(-c2c(Cl)cncc2Cl)c2cc(C(N)=O)ccc12
56,666,822
CCOc1ccc2c(c1)sc1nc(-c3ccccc3)c(Cn3cccc3)n12
140,984,735
CC(C(=O)O)c1cccc(NC(=O)N2CCN(C3CCNCC3)CC2)c1
57,505,154
Cc1c(-c2ccc(=O)n(Cc3ccc(F)cc3)n2)c2cc(F)ccc2n1CC(=O)O
100,504,785
CCOc1ccc(-c2cnc(-c3ccccc3C(=O)Nc3ccc(OC)c(Cl)c3)o2)cc1
44,527,562
O=C(NC1CC1)c1cnc(N2CCC(OCc3ccccc3)CC2)c(Cl)c1
95,552,910
Cc1ccsc1-c1cc(C(=O)O)cc(S(=O)(=O)NC[C@H]2CCCO2)c1
91,787,435
CC(=O)NC1CC(c2cc(N(C)CCc3cnn(C)c3)nc(C)n2)C1
158,564,641
C(=C/c1ccc2cc(N(c3ccccc3)c3ccc4ccccc4c3)ccc2c1)\c1ccc2cc(-c3ccc(-c4ccccc4)s3)ccc2c1.C(=C/c1ccc2cc(N(c3ccccc3)c3cccc4ccccc34)ccc2c1)\c1ccc2cc(/C=C/c3nc4ccccc4n3-c3ccccc3)ccc2c1.CC(C)(C)c1ccc(-c2ncc(-c3ccc4cc(/C=C/c5ccc6cc(-c7cnc(-c8ccc(C(C)(C)C)cc8)nc7)ccc6c5)ccc4c3)cn2)cc1.Cn1c(-c2ccccc2)ccc1-c1ccc2cc(/C=C/c3ccc4cc(N(c...
134,181,330
COCc1cnc2c(-c3nc4c(s3)C(O)C(C)(C)CC4)cc(C)cc2n1
118,722,323
O=C(NC[C@@H]1CC(Br)=NO1)[C@@H]1CCCN1C(=O)OCc1ccccc1
22,636,893
CCOc1cc(CO)cc(OCC)c1I
2,236,993
Cc1ccc(O[C@@H](C)C(=O)Nc2sc(C)c(C)c2C(N)=O)cc1
88,154,188
C#C.O=C(O)OC(=O)O
2,109,828
C[C@H]1Cc2ccccc2N1C(=O)CSc1nnnn1-c1ccc(O)cc1
158,094,208
CCNc1nc(C(=O)NCN(CC(O)C(O)C(O)C(O)CO)CC(O)C(O)C(O)C(O)CO)c(NCC)nc1C(=O)CCN(CC(O)C(O)C(O)C(O)CO)CC(O)C(O)C(O)C(O)CO.CCNc1nc(C(=O)NCN(CC(O)C(O)C(O)C(O)CO)CC(O)C(O)C(O)C(O)CO)c(NCC)nc1C(=O)CCN(CC(O)C(O)C(O)CO)CC(O)C(O)C(O)C(O)CC
58,954,833
CNC[C@@]1(c2ccc(Cl)cc2)CCCC[C@@H]1O
5,117,848
COc1ccc(C(=O)Nc2ccc3oc(-c4ccc(C)c(C)c4)nc3c2)cc1Br
143,919,123
C=C(C)C(=O)OC(C)(C)CCCCCC(=O)OC(C)(C)CCCCCCCCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCCCCCC)cc3)cc2)cc1
139,935,133
CCCCCCCCCCCCCCCCCCC(CO)C(O)CC
140,241,860
CCCCCCCCCC=CC=CC=CC=CC=CC(=O)CCCCCCCCCC=CC=CC=CC=CC=CC(=O)Cl
152,908,195
CCOC(=O)C(/C=C/c1ccccc1)C(O)c1cccs1
124,249,240
O=S1(=O)CCCC[C@@]12CCCNC2
126,173,371
COc1ccccc1N1C(=O)/C(=C/c2ccc(OC)c3ccccc23)C(=O)NC1=S
144,043,820
CC.CCC(=O)C1CCC(=O)N1
142,500,915
CCN(C(=O)c1cc(-c2cnn(-c3c(C(F)(F)F)c(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)nn3C)c2)ccc1Cl)C1CC1
130,365,552
C/C(=C\[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NCC(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)O)C(C)C
134,313,788
N/C=C\C1=NCCN(C[C@@H]2CC(F)(F)[C@H](n3ccc(N)nc3=O)O2)C1
68,383,800
IOc1ccc2c(oc3ccccc32)c1C1C=CC=CC1
158,539,016
C.FC1(F)OC(C(F)(F)F)C(F)(Cl)O1.FC1=C(C(F)(F)F)OC(F)(F)O1
144,746,414
Cc1ccc(NC(=O)[C@@H]2CSc3c(C4CC4)c(Cc4cccc5ccccc45)cc(=O)n32)cc1
67,430,590
O=C(O)CC(c1cccc(OCc2ccccc2)c1)c1ccon1
154,657,853
Cn1ccc(-c2nc(N)c(OCc3cccc(COC4CCOC4)n3)nc2-c2cc(Cl)c3ncccc3c2)n1
145,186,951
COCCN1CCC2(c3cc(O)ccc3C)CCCCC2C1C
110,118
C=CCOCC(CC)(COCC=C)COC(=O)NC1CCC(CC2CCC(NC(=O)OCC(CC)(COCC=C)COCC=C)CC2)CC1
169,215,444
O=C(NC1CC(NCCc2ccc(Cl)cc2)C1)c1cc(F)cc(Cl)c1
119,413,585
N[C@@H]1CCN(C(=O)c2cc(=O)[nH]c3c(Br)cccc23)C1
88,227,238
C=C(/C=C\C=C/C)COC(=O)NC1(CO)CC1
57,593,845
O=C(O)CNC(=O)c1ccc(Nc2ncc(Br)c(NCCc3cnc[nH]3)n2)cc1
68,229,327
CC1CC(C)C1(CI)C(C)(C)C
135,913,572
COc1ccc([C@@H]2CC(=O)C3=C(C2)Nc2ncnn2[C@H]3c2ccccc2[N+](=O)[O-])cc1OC
130,217,935
C=C(C)/C=C\C1Oc2ccc(N)cc2C1C
136,464,905
O=C(/C=C/c1cccc(C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2)c1)NO
66,851,040
CN(C)[C@@](C)(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
153,352,280
[H]/N=c1\c(=O)c(=O)c2ccccc2\c1=N\NC1CCN(C)CC1
44,406,260
Cc1ccsc1C(=CCCN1CCCCC1C(=O)O)c1sccc1C
124,940,200
CNc1cc(C)nc([C@H]2CN(C(=O)c3ccccc3OC)CCO2)c1
18,470,339
CCCCCCCCCCc1cccc(-n2cc(Cc3cncnc3)c(=O)nc2SCc2ccc(F)cc2)c1
134,530,071
Clc1ccc2c(c1)-c1oc3ccccc3c1C21c2ccccc2-c2c(Br)cccc21
1,264,917
C=CCn1c(SC[C@H]2CCCCO2)nc2sc3c(c2c1=O)CCCC3
44,360,936
CC1OC(OC2CCCCC2OC2OC(CN)C(O)C(O[C@@H](Cc3ccccc3)C(=O)O)C2O)C(O)C(O)C1O
156,052,041
CCCC[N+](CC)(CCCC)CCCCC[N+](CC)(CC)CC
24,823,885
COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2c(OC)ccc(OC)c2[N+](=O)[O-])nc2sc(Cl)cn12
121,452,854
CC(=O)N[C@@H]1[C@@H]([C@H](O)[C@H](O)CO)O[C@](O[C@@H]2[C@@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](CO[C@]4(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O4)O[C@@H](O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](OCCCCCN)[C@@H]4O)[C@@H]3NC(C)=O)O[C@H](CO)[C@@H]2O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(C(=O)O)C[C@H]1O
155,702,433
c1ccc(N2c3ccccc3B3c4ccccc4N(c4ccccc4)c4cc(-c5cccc([Si](c6ccccc6)(c6ccccc6)c6ccccc6)c5)cc2c43)cc1
160,746,561
CCOC(=O)c1c(O)nc2ccc(-c3ccccc3C(F)(F)F)nn12.CCOC(=O)c1c(O)nc2ccc(Cl)nn12.Cc1ccccc1C(F)(F)F
126,648,199
CC(C)n1cc(Nc2nc3cc(OC4CCNCC4)ccc3n3ccnc23)cn1
129,364,535
C[C@H](Br)C(=O)OCC1CCCCC1
162,209,465
c1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C3(c5ccccc5-c5cc6c7cc8ccccc8cc7n(-c7ccccc7)c6cc53)c3ncncc3-4)c3ccccc23)cc1.c1ccc(-n2c3ccccc3c3cc4c(cc32)C2(c3ccccc3-4)c3cc(-c4c5ccccc5c(-c5cccc6ccccc56)c5ccccc45)ccc3-c3nccnc32)cc1.c1ccc(-n2c3ccccc3c3cc4c(cc32)C2(c3ccccc3-4)c3cc(-c4c5ccccc5c(-c5cccc6ccccc56)c5ccccc45)ccc3-c3ncncc32)cc1.c1...
140,750,362
[C-]#[N+]c1ccc(C(CC(=O)O)c2ccc(C)c(CN3CC(CC)Oc4ccccc4S3(=O)=O)c2)c(C)c1
53,115,720
O=C(CCc1nc(N2CCCCC2)c2c(-c3ccc(F)cc3)noc2n1)N1CCOCC1
117,854,826
N#CC(Cc1cncnc1)c1ccc(C#CC2CC2)cc1
9,542,069
CCOc1ccc(C(O)=C2C(=O)C(=O)N(CCc3ccccc3)[C@H]2c2ccc(OCc3ccccc3)c(OC)c2)cc1
162,356,374
CCNC(=O)c1cc2c(-c3cc4c(cc3Oc3c(C)cccc3C)c(N(C)CCN3CCN(C)CC3)nn4CC(C)(C)F)cn(C)c(=O)c2[nH]1
25,346,847
CN1c2ccccc2C(=O)N[C@@H]1/C=C/c1cn(Cc2ccccc2)nn1
59,536,796
CCS(=O)(=O)NCC(NC(=O)OC(C)(C)C)c1ccccc1Cl
58,365,980
Cc1nc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)no1
142,864,236
Cc1cc(C)cc(-c2[nH]c3sc(C(C)(C)C(=O)C=C4C5CCC4CC5)cc3c2CCC2CCC(N3CCOCC3)C2)c1
30,165,318
CCOc1ccc(S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(CC)cc2)cc1C
20,064,247
O=C(O)c1cc(C(=O)O)c(C(=O)Nc2ccc(O)cc2)cc1C(=O)Nc1ccc(O)cc1
123,989,971
[C-]#[N+]c1ccc(N2N=C3c4ccc(C(=O)NCCS(C)(=O)=O)nc4CCC3C2C2CCCC2)cc1Cl
125,064,884
COc1ccc(S(=O)(=O)N(CC(=O)N(Cc2ccccc2F)[C@H](Cc2ccccc2)C(=O)NC(C)C)c2cc(C)cc(C)c2)cc1OC
159,623,553
CCc1ccc(N(c2cc(-c3ccccc3)cc(-c3ccc(C)cc3)c2)c2ccc3ccc4c(N(c5ccc(CC)cc5)c5cc(-c6ccccc6)cc(-c6ccc(C)cc6)c5)ccc5ccc2c3c54)cc1.Cc1ccc(-c2cc(-c3ccccc3)cc(N(c3c(C)cccc3F)c3ccc4ccc5c(N(c6cc(-c7ccccc7)cc(-c7ccc(C)cc7)c6)c6c(C)cccc6F)ccc6ccc3c4c65)c2)cc1
146,541,590
N#Cc1cnc2c(c1)nc1n2CC(F)(F)COP(=O)(S)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](OP(O)(=S)OC1)[C@@H]2F
95,091,917
CC(C)c1ccc(C(=O)N[C@H](C)C(=O)N2CCCc3ccccc32)cc1
146,323,999
CCC(C)(CC(C)(C)I)C(=O)OC(C)(C)C(O)(C(F)(F)F)C(F)(F)F
161,601,655
COCCN1/C(=C/C=C2\CCC3CCC(/C=C/C4=[N+](CCOC)c5ccc(C)cc5C4(C)C)=C4Oc5ccc(CCC(=O)O)cc5OC2=C43)C(C)(C)c2cc(S(=O)(=O)ON)ccc21
167,485,360
Cn1c(=O)n(C)c2cc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5cccc6ccccc56)n4)cc3)ccc21
68,809,220
COC(=O)C1CCC(c2c(F)cnc3[nH]c(=O)n(C4CCC(NC(=O)C5CC5)CC4)c(=O)c23)CC1
140,664,682
Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCOc2[nH]ccc(=O)c21
152,779,647
Cc1ccc(C(N)=O)c(NC(=O)c2ccc(O)cc2)c1
167,220,999
C/C1=N/N(C)[C@H](C)CN(C(C)c2ccc(S(C)(=O)=NC#N)cc2)N(C(=O)c2ccc(Cl)c(C(F)(F)F)c2)[C@H](C)C1
156,936,948
CCCCCCCCCCCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCCCCCCCCCCC(C)C)COP(=O)(O)OC[C@@H](O)COP(=O)(O)OC[C@@H](COC(=O)CCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC(C)CC
123,957,092
C=C[SiH](c1ccccc1)C(OC)OC
132,510,853
COc1ccc2[nH]c3c(c2c1)CCN(C(=O)c1ccccc1)C3c1ccc(Cl)c(Cl)c1
44,527,425
COc1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)c2cc(C3CCCC3)cc(N3CCCCS3(=O)=O)c2)c1
92,336,092
COc1ccc(N2CCN([C@@H](CNC(=O)c3c(F)cccc3F)c3ccc4c(c3)OCO4)CC2)cc1
90,247,551
COc1ccc([C@@H]2CN3CCNC[C@H]3CO2)c(C)c1C#N
6,263,379
CC(C)(C)C(=O)/C(C#N)=C/Nc1ccc(F)cc1C(F)(F)F
134,451,841
C1CC12CCC1(CC2)CO1
16,610,516
CCCn1c(=O)c2c(nc3n(-c4ccccc4N)c(C)c(C)n23)n(C)c1=O
68,428,610
CCOC(=O)CN(Cc1ccc(OC)cc1OC)Cc1nc(-c2ccc(Oc3ccccc3)cc2)sc1C(=O)OCC
77,269,963
CC1=NC2=Cc3nnc(Cl)cc3C(=O)C2OC=C1
146,436,911
c1ccc2c(c1)cc1c3c4ccccc4c4cc(-c5ccc6cc7c8c9ccccc9c9ccccc9c8c8nc9nccnc9nc8n7c6c5)ccc4c3c3nc4ccccc4nc3n21
17,995,641
CCOC(=O)C1=C(COCCN2C(=O)c3ccccc3C2=O)NC(CF)=C(C(=O)OC)C1c1c(F)ccc(Cl)c1C(F)(F)F
140,492,773
CCn1c(=O)c2ccc(N)cc2c(=O)n1CC
155,453,737
Cc1cc2n(n1)CCC21CCC1