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32,094,225
J Biol Chem
The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
Antiviral drugs for managing infections with human coronaviruses are not yet approved, posing a serious challenge to current global efforts aimed at containing the outbreak of severe acute respiratory syndrome-coronavirus 2 (CoV-2). Remdesivir (RDV) is an investigational compound with a broad spectrum of antiviral acti...
ebola virus (ebov);middle east respiratory syndrome coronavirus (mers-cov);rna chain termination;rna-dependent rna polymerase (rdrp);sars-cov-2;antiviral drug;coronavirus;drug development;enzyme inhibitor;nucleoside/nucleotide analog;plus-stranded rna virus;positive-sense rna virus;remdesivir;viral polymerase;viral rep...
Journal Article;Research Support, Non-U.S. Gov't
Gordon, Calvin J;Tchesnokov, Egor P;Feng, Joy Y;Porter, Danielle P;Gotte, Matthias
10.1074/jbc.AC120.013056
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus. [Abstract]: Antiviral drugs for managing infections with human coronaviruses are not yet approved, posing a serious challenge to current global efforts aimed at containing the out...
32,838,328
Arthrosc Sports Med Rehabil
COVID-19 and Orthopaedics: Recovery After the Pandemic Surge.
The novel Coronavirus (COVID-19) pandemic has placed an immense strain on health care systems and orthopedic surgeons across the world. To limit the spread, federal and state governments mandated the cancellation of all nonurgent surgical cases to address surging hospital admissions and manage workforce and resource re...
Journal Article
Petrone, Brandon;Iturriaga, Cesar R;Mauri, Thomas;Sgaglione, Nicholas
10.1016/j.asmr.2020.05.009
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and Orthopaedics: Recovery After the Pandemic Surge. [Abstract]: The novel Coronavirus (COVID-19) pandemic has placed an immense strain on health care systems and orthopedic surgeons across the world. To limit the spread, federal and state governments mandated the cancellation of all nonurgent surgica...
32,418,028
World J Surg
Hazardous Postoperative Outcomes of Unexpected COVID-19 Infected Patients: A Call for Global Consideration of Sampling all Asymptomatic Patients Before Surgical Treatment.
BACKGROUND: In December 2019, a novel coronavirus was identified as the cause of many pneumonia cases in China and eventually declared as a pandemic as the virus spread globally. Few reports were published on the outcome of surgical procedures in diagnosed COVID-19 patients and even fewer on the surgical outcomes of as...
Journal Article;Review
Nahshon, Chen;Bitterman, Arie;Haddad, Riad;Hazzan, David;Lavie, Ofer
10.1007/s00268-020-05575-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Hazardous Postoperative Outcomes of Unexpected COVID-19 Infected Patients: A Call for Global Consideration of Sampling all Asymptomatic Patients Before Surgical Treatment. [Abstract]: BACKGROUND: In December 2019, a novel coronavirus was identified as the cause of many pneumonia cases in China and eventually d...
32,782,765
Eur J Transl Myol
Neuromuscular diseases and Covid-19: Advices from scientific societies and early observations in Italy.
The risk of a severe course of COVID-19 is increased in patients suffering with Neuromuscular disorders (NMD) due to the following comorbidities: muscular weakness of the chest and diaphragm, use of ventilator supports and/or presence of tracheostoma, weak airway clearance, cardiac involvement, rhabdomyolysis, comoribi...
aigkit application;aim;covid-19;advice from scientific societies;neuromuscular disorders
Journal Article
Angelini, Corrado;Siciliano, Gabriele
10.4081/ejtm.2019.9032
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Neuromuscular diseases and Covid-19: Advices from scientific societies and early observations in Italy. [Abstract]: The risk of a severe course of COVID-19 is increased in patients suffering with Neuromuscular disorders (NMD) due to the following comorbidities: muscular weakness of the chest and diaphragm, use...
32,350,796
Radiol Med
It's not over until it's over: the chameleonic behavior of COVID-19 over a six-day period.
The current global outbreak of COVID-19 represents a major challenge in terms of epidemiology, contagiousness, treatment, as well as clinical and radiological behavior of this disease. Radiological imaging plays a key role in the diagnostic process and during the monitoring of the clinical conditions especially of pati...
covid-19;chest x-ray;outbreak;radiology
Journal Article
Fichera, Giulia;Stramare, Roberto;De Conti, Giorgio;Motta, Raffaella;Giraudo, Chiara
10.1007/s11547-020-01203-0
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: It's not over until it's over: the chameleonic behavior of COVID-19 over a six-day period. [Abstract]: The current global outbreak of COVID-19 represents a major challenge in terms of epidemiology, contagiousness, treatment, as well as clinical and radiological behavior of this disease. Radiological imaging pl...
33,045,427
Int J Infect Dis
Proof of SARS-CoV-2 genomes in endomyocardial biopsy with latency after acute infection.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has reached pandemic levels. Cardiovascular complications in COVID-19 have been reported frequently, however evidence for a causal relationship has not been established. This report...
covid-19;endomyocardial biopsy;sars-cov-2;viral myocarditis
Case Reports
Pietsch, Heiko;Escher, Felicitas;Aleshcheva, Ganna;Baumeier, Christian;Morawietz, Lars;Elsaesser, Albrecht;Schultheiss, Heinz-Peter
10.1016/j.ijid.2020.10.012
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Proof of SARS-CoV-2 genomes in endomyocardial biopsy with latency after acute infection. [Abstract]: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has reached pandemic levels. Cardiovascular complications in COVID-19 h...
32,645,276
Crit Rev Clin Lab Sci
The COVID-19 pandemic.
In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan, Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan Seafood Wholesale Market. Inoculation of respiratory samples into human airway epithelial cells, Vero E6 and Huh7 cell lines, led to the isolation of a n...
ace2;covid-19;sars-cov-2;cytokine storm;pneumonia;rrt-pcr;serology
Journal Article;Review
Ciotti, Marco;Ciccozzi, Massimo;Terrinoni, Alessandro;Jiang, Wen-Can;Wang, Cheng-Bin;Bernardini, Sergio
10.1080/10408363.2020.1783198
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 pandemic. [Abstract]: In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan, Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan Seafood Wholesale Market. Inoculation of respiratory samples into human airway epithelial cells, Vero E6 and ...
33,032,673
Br J Nutr
Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19.
The recent COVID-19 pandemic has altered the face of biology, social interaction and public health worldwide. It has had a destructive effect upon millions of people and is approaching a devastating one million fatalities. Emerging evidence has suggested a link between the infection and gut microbiome status. This is o...
covid-19;coronavirus;gut microbiome;prebiotics;probiotics
Journal Article
Walton, Gemma E;Gibson, Glenn R;Hunter, Kirsty A
10.1017/S0007114520003980
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Mechanisms linking the human gut microbiome to prophylactic and treatment strategies for COVID-19. [Abstract]: The recent COVID-19 pandemic has altered the face of biology, social interaction and public health worldwide. It has had a destructive effect upon millions of people and is approaching a devastating o...
32,838,236
EClinicalMedicine
Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery.
Background: The long-term pulmonary function and related physiological characteristics of COVID-19 survivors have not been studied in depth, thus many aspects are not understood. Methods: COVID-19 survivors were recruited for high resolution computed tomography (HRCT) of the thorax, lung function and serum levels of SA...
covid-19;follow-up study;pulmonary function;recovered patients;serum marker
Journal Article
Zhao, Yu-Miao;Shang, Yao-Min;Song, Wen-Bin;Li, Qing-Quan;Xie, Hua;Xu, Qin-Fu;Jia, Jun-Li;Li, Li-Ming;Mao, Hong-Li;Zhou, Xiu-Man;Luo, Hong;Gao, Yan-Feng;Xu, Ai-Guo
10.1016/j.eclinm.2020.100463
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. [Abstract]: Background: The long-term pulmonary function and related physiological characteristics of COVID-19 survivors have not been studied in depth, thus many aspects are n...
33,069,957
Biosens Bioelectron
Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform.
The 2019 SARS CoV-2 (COVID-19) pandemic has illustrated the need for rapid and accurate diagnostic tests. In this work, a multiplexed grating-coupled fluorescent plasmonics (GC-FP) biosensor platform was used to rapidly and accurately measure antibodies against COVID-19 in human blood serum and dried blood spot samples...
antibody;biosensor;covid-19;multiplex;plasmonic;quantitative
Evaluation Study;Journal Article
Cady, Nathaniel C;Tokranova, Natalya;Minor, Armond;Nikvand, Nima;Strle, Klemen;Lee, William T;Page, William;Guignon, Ernest;Pilar, Arturo;Gibson, George N
10.1016/j.bios.2020.112679
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform. [Abstract]: The 2019 SARS CoV-2 (COVID-19) pandemic has illustrated the need for rapid and accurate diagnostic tests. In this work, a multiplexed grating-coupled fluorescent pl...
32,662,314
J Matern Fetal Neonatal Med
Personal Protective Equipment during the COVID-19 pandemic and operative time in cesarean section: retrospective cohort study.
INTRODUCTION: The covid-19 pandemic has meant a change in working protocols, as well as in Personal Protective Equipment (PPE). Obstetricians have had to adapt quickly to these changes without knowing how they affected their clinical practice. The aim of the present study was to evaluate how COVID-19 pandemic and PPE c...
covid-19;cesarean section;personal protective equipment;operative time;pandemics
Journal Article
Cuerva, Marcos Javier;Carbonell, Maria;Martin Palumbo, Giovanna;Lopez Magallon, Sara;De La Calle, Maria;Bartha, Jose Luis
10.1080/14767058.2020.1793324
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Personal Protective Equipment during the COVID-19 pandemic and operative time in cesarean section: retrospective cohort study. [Abstract]: INTRODUCTION: The covid-19 pandemic has meant a change in working protocols, as well as in Personal Protective Equipment (PPE). Obstetricians have had to adapt quickly to t...
32,220,180
Sichuan Da Xue Xue Bao Yi Xue Ban
[Oral Health Management of Children during the Epidemic Period of Coronavirus Disease 2019].
Coronavirus disease 2019 (COVID-19) is becoming a major public health event affecting China and even the whole world. During the epidemic period of corona virus disease, appropriate oral health management and disease prevention of children is very important for children's oral and general health. In order to prevent th...
children;coronavirus disease 2019;oral emergency;oral health management
Journal Article;Review
Wang, Yan;Zhou, Chen-Chen;Shu, Rui;Zou, Jing
10.12182/20200360101
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Oral Health Management of Children during the Epidemic Period of Coronavirus Disease 2019]. [Abstract]: Coronavirus disease 2019 (COVID-19) is becoming a major public health event affecting China and even the whole world. During the epidemic period of corona virus disease, appropriate oral health management a...
32,834,659
Chaos Solitons Fractals
Modelling and forecasting of new cases, deaths and recover cases of COVID-19 by using Vector Autoregressive model in Pakistan.
COVID-19 emerged in Wuhan, China in December 2019 has now spread around the world causes damage to human life and economy. Pakistan is also severely effected by COVID-19 with 202,955 confirmed cases and total deaths of 4,118. Vector Autoregressive time series models was used to forecast new daily confirmed cases, death...
covid-19;confirmed cases;death;forecasting;recoveries;vector autoregressive model, time series
Journal Article
Khan, Firdos;Saeed, Alia;Ali, Shaukat
10.1016/j.chaos.2020.110189
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Modelling and forecasting of new cases, deaths and recover cases of COVID-19 by using Vector Autoregressive model in Pakistan. [Abstract]: COVID-19 emerged in Wuhan, China in December 2019 has now spread around the world causes damage to human life and economy. Pakistan is also severely effected by COVID-19 wi...
32,819,484
JACC Cardiovasc Interv
Shifting Paradigms in Cardiovascular Therapeutic Strategies During the COVID-19 Era.
The coronavirus disease-19 (COVID-19) period have dictated a different approach to cardiac interventions at our medical institution. We prioritize emergent care geared toward lesser invasive approaches while minimizing hospitalization duration. This reflects upon coronary and structural/valvular cases altogether. Despi...
covid-19;heart team;percutaneous coronary interventions;transcatheter aortic valve replacement
Journal Article;Review
Kornowski, Ran
10.1016/j.jcin.2020.05.028
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Shifting Paradigms in Cardiovascular Therapeutic Strategies During the COVID-19 Era. [Abstract]: The coronavirus disease-19 (COVID-19) period have dictated a different approach to cardiac interventions at our medical institution. We prioritize emergent care geared toward lesser invasive approaches while minimi...
32,800,515
Transplant Proc
Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report.
The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have plummeted as a result of fear of disease transmission, recipient coronavirus disease 2019 infection, priority shift, and resource limitations. Severe acute respiratory syndrome coronavirus 2 (SARS-C...
Case Reports;Journal Article
Bogensperger, Christina;Cardini, Benno;Oberhuber, Rupert;Weissenbacher, Annemarie;Gasteiger, Silvia;Berchtold, Valeria;Otarashvili, Giorgi;Ofner, Dietmar;Schneeberger, Stefan
10.1016/j.transproceed.2020.07.011
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have pl...
32,259,247
Pain Med
Pain Management Best Practices from Multispecialty Organizations During the COVID-19 Pandemic and Public Health Crises.
BACKGROUND: It is nearly impossible to overestimate the burden of chronic pain, which is associated with enormous personal and socioeconomic costs. Chronic pain is the leading cause of disability in the world, is associated with multiple psychiatric comorbidities, and has been causally linked to the opioid crisis. Acce...
covid-19;pain management;pandemic;public health crisis;sars-cov-2
Journal Article
Cohen, Steven P;Baber, Zafeer B;Buvanendran, Asokumar;McLean, Brian C;Chen, Yian;Hooten, W Michael;Laker, Scott R;Wasan, Ajay D;Kennedy, David J;Sandbrink, Friedhelm;King, Scott A;Fowler, Ian M;Stojanovic, Milan P;Hayek, Salim M;Phillips, Christopher R
10.1093/pm/pnaa127
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pain Management Best Practices from Multispecialty Organizations During the COVID-19 Pandemic and Public Health Crises. [Abstract]: BACKGROUND: It is nearly impossible to overestimate the burden of chronic pain, which is associated with enormous personal and socioeconomic costs. Chronic pain is the leading cau...
33,025,199
Arch Virol
Identification of novel mutations in SARS-COV-2 isolates from Turkey.
SARS-CoV-2 was first detected in the city of Wuhan, Hubei Province, China. In this study, we identified 11 unique mutations in viral SARS-COV-2 isolates from Turkey. Nine of them cause structural alterations in the S protein, nsp2, nsp3, nsp4 and nsp12 regions. The mutations identified here might have significant funct...
Journal Article
Rehman, Shazia;Mahmood, Tariq;Aziz, Ejaz;Batool, Riffat
10.1007/s00705-020-04830-0
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Identification of novel mutations in SARS-COV-2 isolates from Turkey. [Abstract]: SARS-CoV-2 was first detected in the city of Wuhan, Hubei Province, China. In this study, we identified 11 unique mutations in viral SARS-COV-2 isolates from Turkey. Nine of them cause structural alterations in the S protein, nsp...
32,438,383
N Z Med J
Inhaled modified angiotensin converting enzyme 2 (ACE2) as a decoy to mitigate SARS-CoV-2 infection.
COVID-19 is a new zoonotic disease caused by the SARS-CoV-2 virus. Since its emergence in Wuhan City, China, the virus has rapidly spread across the globe causing calamitous health, economic and societal consequences. It causes disproportionately severe disease in the elderly and those with co-morbidities, such as hype...
Journal Article
Ameratunga, Rohan;Lehnert, Klaus;Leung, Euphemia;Comoletti, Davide;Snell, Russell;Woon, See-Tarn;Abbott, William;Mears, Emily;Steele, Richard;McKee, Jeff;Muscroft-Taylor, Andrew;Ameratunga, Shanthi;Medlicott, Natalie;Das, Shyamal;Rolleston, William;Quinones-Mateu, Miguel;Petousis-Harris, Helen;Jordan, Anthony
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Inhaled modified angiotensin converting enzyme 2 (ACE2) as a decoy to mitigate SARS-CoV-2 infection. [Abstract]: COVID-19 is a new zoonotic disease caused by the SARS-CoV-2 virus. Since its emergence in Wuhan City, China, the virus has rapidly spread across the globe causing calamitous health, economic and soc...
32,992,643
Int J Environ Res Public Health
Data Analytics for Predicting COVID-19 Cases in Top Affected Countries: Observations and Recommendations.
The outbreak of the 2019 novel coronavirus disease (COVID-19) has adversely affected many countries in the world. The unexpected large number of COVID-19 cases has disrupted the healthcare system in many countries and resulted in a shortage of bed spaces in the hospitals. Consequently, predicting the number of COVID-19...
covid-19;data analytics;neural network;pandemic
Journal Article
Eltoukhy, Abdelrahman E E;Shaban, Ibrahim Abdelfadeel;Chan, Felix T S;Abdel-Aal, Mohammad A M
10.3390/ijerph17197080
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Data Analytics for Predicting COVID-19 Cases in Top Affected Countries: Observations and Recommendations. [Abstract]: The outbreak of the 2019 novel coronavirus disease (COVID-19) has adversely affected many countries in the world. The unexpected large number of COVID-19 cases has disrupted the healthcare syst...
32,740,801
Arch Pharm Res
Hydroxychloroquine and chloroquine: a potential and controversial treatment for COVID-19.
A novel coronavirus, later named SARS-CoV-2, was first reported in China in December 2019 and subsequently widely identified in the United States, Japan, South Korea, France, India, and other countries. The disease caused by SARS-CoV-2 infection was called COVID-19. The high fatality and morbidity rates of COVID-19 mak...
covid-19;chloroquine;hydroxychloroquine;sars-cov-2;treatment
Journal Article;Review
Zou, Li;Dai, Lijun;Zhang, Xingyu;Zhang, Zhaohui;Zhang, Zhentao
10.1007/s12272-020-01258-7
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine and chloroquine: a potential and controversial treatment for COVID-19. [Abstract]: A novel coronavirus, later named SARS-CoV-2, was first reported in China in December 2019 and subsequently widely identified in the United States, Japan, South Korea, France, India, and other countries. The di...
32,557,972
Head Neck
Head and neck cancer radiotherapy amid COVID-19 pandemic: Report from Milan, Italy.
BACKGROUND: Management of head and neck cancers (HNC) in radiation oncology in the coronavirus disease 2019 (COVID-19) era is challenging. Aim of our work is to report organization strategies at a radiation therapy (RT) department in the first European area experiencing the COVID-19 pandemic. METHODS: We focused on (a)...
covid-19;departmental procedures;head and neck cancer;health care protections;radiation oncology
Journal Article
Alterio, Daniela;Volpe, Stefania;Marvaso, Giulia;Turturici, Irene;Ferrari, Annamaria;Leonardi, Maria Cristina;Lazzari, Roberta;Fiore, Massimo Sarra;Bufi, Giammaria;Cattani, Federica;Arrobbio, Camilla;Patti, Filippo;Casbarra, Alessia;Cavallo, Iacopo;Mastrilli, Fabrizio;Orecchia, Roberto;Jereczek-Fossa, Barbara Alicja
10.1002/hed.26319
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Head and neck cancer radiotherapy amid COVID-19 pandemic: Report from Milan, Italy. [Abstract]: BACKGROUND: Management of head and neck cancers (HNC) in radiation oncology in the coronavirus disease 2019 (COVID-19) era is challenging. Aim of our work is to report organization strategies at a radiation therapy ...
32,284,616
Nat Med
Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China.
As of 29 February 2020 there were 79,394 confirmed cases and 2,838 deaths from COVID-19 in mainland China. Of these, 48,557 cases and 2,169 deaths occurred in the epicenter, Wuhan. A key public health priority during the emergence of a novel pathogen is estimating clinical severity, which requires properly adjusting fo...
Letter;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Wu, Joseph T;Leung, Kathy;Bushman, Mary;Kishore, Nishant;Niehus, Rene;de Salazar, Pablo M;Cowling, Benjamin J;Lipsitch, Marc;Leung, Gabriel M
10.1038/s41591-020-0822-7
[ 0, 0, 0, 0, 1, 1, 0 ]
[Title]: Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China. [Abstract]: As of 29 February 2020 there were 79,394 confirmed cases and 2,838 deaths from COVID-19 in mainland China. Of these, 48,557 cases and 2,169 deaths occurred in the epicenter, Wuhan. A key public health priority ...
32,404,189
Eur J Med Res
The role of passive immunization in the age of SARS-CoV-2: an update.
The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-2 virus. In this review, we describe the role of passive immunization in times of the corona virus. Passive imm...
bridge therapy;convalescent plasma;covid-19;high risk;immunology;intensive care unit;respiratory failure
Journal Article;Review
Fischer, Johannes C;Zanker, Kurt;van Griensven, Martijn;Schneider, Marion;Kindgen-Milles, Detlef;Knoefel, Wolfram Trudo;Lichtenberg, Artur;Tamaskovics, Balint;Djiepmo-Njanang, Freddy Joel;Budach, Wilfried;Corradini, Stefanie;Ganswindt, Ute;Haussinger, Dieter;Feldt, Torsten;Schelzig, Hubert;Bojar, Hans;Peiper, Matthias;...
10.1186/s40001-020-00414-5
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The role of passive immunization in the age of SARS-CoV-2: an update. [Abstract]: The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-2 virus. In this rev...
32,980,021
Environ Res
Understanding the knowledge gaps between air pollution controls and health impacts including pathogen epidemic.
Sustainable development calls for a blue sky with quality air. Encouragingly, the current mass reduction-oriented pollution control is making substantial achievements, as the data from Chinese Environmental Monitoring Stations show a significant drop in the annual average concentrations of particulate matters (i.e., PM...
air pollution;health impacts;mass control;pathogen epidemic;pollutants
Journal Article;Research Support, Non-U.S. Gov't
Ma, Qingxin;Qi, Yu;Shan, Qiuli;Liu, Sijin;He, Hong
10.1016/j.envres.2020.109949
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Understanding the knowledge gaps between air pollution controls and health impacts including pathogen epidemic. [Abstract]: Sustainable development calls for a blue sky with quality air. Encouragingly, the current mass reduction-oriented pollution control is making substantial achievements, as the data from Ch...
32,721,808
Med Hypotheses
Prior infection with intestinal coronaviruses moderates symptom severity and mortality in patients with COVID-19: A hypothesis and preliminary evidence.
The pandemic of acute respiratory illness caused by the novel betacoronavirus SARS-CoV-2, officially designated COVID-19, has attained the proportions of a global health crisis. Though all nations of the world have been affected by this disease, there have been marked cross-national variations in prevalence, severity a...
Journal Article
Rajkumar, Ravi Philip
10.1016/j.mehy.2020.110116
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Prior infection with intestinal coronaviruses moderates symptom severity and mortality in patients with COVID-19: A hypothesis and preliminary evidence. [Abstract]: The pandemic of acute respiratory illness caused by the novel betacoronavirus SARS-CoV-2, officially designated COVID-19, has attained the proport...
32,979,319
Cell
Cancer, COVID-19, and Antiviral Immunity: The CAPTURE Study.
The SARS-CoV-2 pandemic has posed a significant challenge for risk evaluation and mitigation among cancer patients. Susceptibility to and severity of COVID-19 in cancer patients has not been studied in a prospective and broadly applicable manner. CAPTURE is a pan-cancer, longitudinal immune profiling study designed to ...
Journal Article;Research Support, Non-U.S. Gov't;Review
Au, Lewis;Boos, Laura Amanda;Swerdlow, Anthony;Byrne, Fiona;Shepherd, Scott T C;Fendler, Annika;Turajlic, Samra
10.1016/j.cell.2020.09.005
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Cancer, COVID-19, and Antiviral Immunity: The CAPTURE Study. [Abstract]: The SARS-CoV-2 pandemic has posed a significant challenge for risk evaluation and mitigation among cancer patients. Susceptibility to and severity of COVID-19 in cancer patients has not been studied in a prospective and broadly applicable...
32,141,279
Zhonghua Liu Xing Bing Xue Za Zhi
[Advances on presymptomatic or asymptomatic carrier transmission of COVID-19].
COVID-19 is rapidly spreading. Patients in incubation period and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is very lacking so far, although there are a few studies suggesting that presympt...
asymptomatic transmission;covid-19;presymptomatic transmission;source of infection
Journal Article
Gao, W J;Li, L M
10.3760/cma.j.cn112338-20200228-00207
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: [Advances on presymptomatic or asymptomatic carrier transmission of COVID-19]. [Abstract]: COVID-19 is rapidly spreading. Patients in incubation period and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The...
32,730,095
Arch Physiol Biochem
COVID-19: a wreak havoc across the globe.
Coronavirus disease (COVID-19) is an infectious airborne viral pneumonia caused by a novel virus belonging to the family coronaviridae. On February 11, 2019, the Internal Committee on Taxonomy of Virus (ICTV) announced the name of the novel virus as "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One of ...
ace2;covid-19;acute respiratory distress syndrome;cellular and humoral immunity;polymerase chain reaction;real time reverse transciptase;spike protein
Journal Article
Rehman, Heena;Ahmad, Md Iftekhar
10.1080/13813455.2020.1797105
[ 1, 1, 1, 1, 1, 0, 0 ]
[Title]: COVID-19: a wreak havoc across the globe. [Abstract]: Coronavirus disease (COVID-19) is an infectious airborne viral pneumonia caused by a novel virus belonging to the family coronaviridae. On February 11, 2019, the Internal Committee on Taxonomy of Virus (ICTV) announced the name of the novel virus as "severe...
31,978,945
N Engl J Med
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel...
Journal Article
Zhu, Na;Zhang, Dingyu;Wang, Wenling;Li, Xingwang;Yang, Bo;Song, Jingdong;Zhao, Xiang;Huang, Baoying;Shi, Weifeng;Lu, Roujian;Niu, Peihua;Zhan, Faxian;Ma, Xuejun;Wang, Dayan;Xu, Wenbo;Wu, Guizhen;Gao, George F;Tan, Wenjie
10.1056/NEJMoa2001017
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: A Novel Coronavirus from Patients with Pneumonia in China, 2019. [Abstract]: In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples fr...
32,639,569
JAMA Netw Open
Association of a Public Health Campaign About Coronavirus Disease 2019 Promoted by News Media and a Social Influencer With Self-reported Personal Hygiene and Physical Distancing in the Netherlands.
Importance: In the absence of a vaccine and therapeutic agent, personal hygiene and physical distancing are essential measures to contain the coronavirus disease 2019 pandemic. Objective: To determine whether a social media campaign, targeted at the gaps in behavior on personal hygiene and physical distancing and distr...
Journal Article;Research Support, N.I.H., Intramural
Yousuf, Hamza;Corbin, Jonathan;Sweep, Govert;Hofstra, Martijn;Scherder, Erik;van Gorp, Eric;Zwetsloot, Peter Paul;Zhao, Jiayu;van Rossum, Bert;Jiang, Ting;Lindemans, Jan-Willem;Narula, Jagat;Hofstra, Leonard
10.1001/jamanetworkopen.2020.14323
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Association of a Public Health Campaign About Coronavirus Disease 2019 Promoted by News Media and a Social Influencer With Self-reported Personal Hygiene and Physical Distancing in the Netherlands. [Abstract]: Importance: In the absence of a vaccine and therapeutic agent, personal hygiene and physical distanci...
33,040,051
Aging (Albany NY)
COVID-19: a risk factor for fatal outcomes in patients with comorbid cardiovascular disease.
OBJECTIVES: To evaluate the fatal impact of COVID-19 on patients with comorbid cardiovascular disease (CVD). RESULTS: Overall, the 28-day mortality of patients with comorbid CVD was 3.25 times of that of patients without comorbid CVD (40.63% vs 12.50%, P=0.011). Clinic symptoms on admission were similar for the two gro...
covid-19;cardiovascular disease;corticosteroids;fatal outcome
Journal Article
Xu, Hui;Ai, Ling;Qiu, Chun;Tan, Xi;Jiao, Bo;Luo, Ailin;Li, Shusheng;Liu, Shangkun;Yan, Li
10.18632/aging.103944
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: a risk factor for fatal outcomes in patients with comorbid cardiovascular disease. [Abstract]: OBJECTIVES: To evaluate the fatal impact of COVID-19 on patients with comorbid cardiovascular disease (CVD). RESULTS: Overall, the 28-day mortality of patients with comorbid CVD was 3.25 times of that of pa...
33,078,030
J Aerosol Sci
Breath-, air- and surface-borne SARS-CoV-2 in hospitals.
The COVID-19 pandemic has brought an unprecedented crisis to the global health sector. When discharging COVID-19 patients in accordance with throat or nasal swab protocols using RT-PCR, the potential risk of reintroducing the infection source to humans and the environment must be resolved. Here, 14 patients including 1...
airborne transmission;covid-19;exhaled breath;sars-cov-2;surface-borne
Journal Article
Zhou, Lian;Yao, Maosheng;Zhang, Xiang;Hu, Bicheng;Li, Xinyue;Chen, Haoxuan;Zhang, Lu;Liu, Yun;Du, Meng;Sun, Bochao;Jiang, Yunyu;Zhou, Kai;Hong, Jie;Yu, Na;Ding, Zhen;Xu, Yan;Hu, Min;Morawska, Lidia;Grinshpun, Sergey A;Biswas, Pratim;Flagan, Richard C;Zhu, Baoli;Liu, Wenqing;Zhang, Yuanhang
10.1016/j.jaerosci.2020.105693
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: Breath-, air- and surface-borne SARS-CoV-2 in hospitals. [Abstract]: The COVID-19 pandemic has brought an unprecedented crisis to the global health sector. When discharging COVID-19 patients in accordance with throat or nasal swab protocols using RT-PCR, the potential risk of reintroducing the infection source...
32,533,615
Transpl Infect Dis
Incidental COVID-19 in a heart-kidney transplant recipient with malnutrition and recurrent infections: Implications for the SARS-CoV-2 immune response.
The clinical course and outcomes of immunocompromised patients, such as transplant recipients, with COVID-19 remain unclear. It has been postulated that a substantial portion of the disease burden seems to be mediated by the host immune activation to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Her...
covid-19;sars-cov-2;immunosuppression;simultaneous heart-kidney transplant
Case Reports
Serrano, Oscar K;Kutzler, Heather L;Rochon, Caroline;Radojevic, Joseph A;Lawlor, Michael T;Hammond, Jonathan A;Gluck, Jason;Feingold, Andrew D;Jaiswal, Abhishek
10.1111/tid.13367
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Incidental COVID-19 in a heart-kidney transplant recipient with malnutrition and recurrent infections: Implications for the SARS-CoV-2 immune response. [Abstract]: The clinical course and outcomes of immunocompromised patients, such as transplant recipients, with COVID-19 remain unclear. It has been postulated...
32,519,138
Dig Dis Sci
Outrunning Burnout in a GI Fellowship Program During the COVID-19 Pandemic.
Many GI training programs have needed to adjust to the serious disruption to the training and education of fellows worldwide due to the COVID-19 pandemic. A silent problem that has arisen within programs is the issue of burnout among their trainees. Burnout is common among gastroenterologists, especially in fellows (Ke...
burnout;covid-19;fellows;pandemic;residency
Editorial
Ong, Andrew Ming-Liang
10.1007/s10620-020-06401-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Outrunning Burnout in a GI Fellowship Program During the COVID-19 Pandemic. [Abstract]: Many GI training programs have needed to adjust to the serious disruption to the training and education of fellows worldwide due to the COVID-19 pandemic. A silent problem that has arisen within programs is the issue of bur...
32,531,308
Int J Surg
International surgical guidance for COVID-19: Validation using an international Delphi process - Cross-sectional study.
BACKGROUND: International professional bodies have been quick to disseminate initial guidance documents during the COVID-19 pandemic. In the absence of firm evidence, these have been developed by expert committees, limited in participant number. This study aimed to validate international COVID-19 surgical guidance usin...
covid-19;delphi consensus;guidance;surgery
Journal Article
Aj, Beamish;C, Brown;T, Abdelrahman;Harper E, Ryan;Rl, Harries;Rj, Egan
10.1016/j.ijsu.2020.06.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: International surgical guidance for COVID-19: Validation using an international Delphi process - Cross-sectional study. [Abstract]: BACKGROUND: International professional bodies have been quick to disseminate initial guidance documents during the COVID-19 pandemic. In the absence of firm evidence, these have b...
32,730,205
Int J Surg
A comparative overview of COVID-19, MERS and SARS: Review article.
Following the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), a third, highly pathogenic coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appearing at end of 2019 led to a pandemic, increased panic and attracted globa...
covid-19;epidemiology;mers;sars;sars-cov-2;treatment
Comparative Study;Journal Article;Review
Liu, Jie;Xie, Wanli;Wang, Yanting;Xiong, Yue;Chen, Shiqiang;Han, Jingjing;Wu, Qingping
10.1016/j.ijsu.2020.07.032
[ 1, 1, 0, 1, 1, 0, 0 ]
[Title]: A comparative overview of COVID-19, MERS and SARS: Review article. [Abstract]: Following the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), a third, highly pathogenic coronavirus, the severe acute respiratory syndrome coronavirus 2 (SAR...
32,147,496
Antiviral Res
Of chloroquine and COVID-19.
Recent publications have brought attention to the possible benefit of chloroquine, a broadly used antimalarial drug, in the treatment of patients infected by the novel emerged coronavirus (SARS-CoV-2). The scientific community should consider this information in light of previous experiments with chloroquine in the fie...
2019-ncov;antiviral;covid-19;chloroquine;sars-cov-2
Journal Article;Review
Touret, Franck;de Lamballerie, Xavier
10.1016/j.antiviral.2020.104762
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Of chloroquine and COVID-19. [Abstract]: Recent publications have brought attention to the possible benefit of chloroquine, a broadly used antimalarial drug, in the treatment of patients infected by the novel emerged coronavirus (SARS-CoV-2). The scientific community should consider this information in light o...
32,164,053
Epidemiol Health
Estimating the reproductive number and the outbreak size of COVID-19 in Korea.
OBJECTIVES: Since the first novel coronavirus disease 2019 (COVID-19) patient in Korea was diagnosed on January 20, 2020, 30 patients were diagnosed until February 17, 2020. However, 5,298 additional patients were confirmed until March 4, 2020. Therefore, our objective was to estimate the reproduction number (R) and ev...
covid-19;epidemiology;korea;mathematical model;outbreak;reproduction number
Journal Article
Choi, Sunhwa;Ki, Moran
10.4178/epih.e2020011
[ 0, 0, 1, 0, 1, 1, 0 ]
[Title]: Estimating the reproductive number and the outbreak size of COVID-19 in Korea. [Abstract]: OBJECTIVES: Since the first novel coronavirus disease 2019 (COVID-19) patient in Korea was diagnosed on January 20, 2020, 30 patients were diagnosed until February 17, 2020. However, 5,298 additional patients were confir...
32,419,177
J Card Surg
Collateral damage of COVID-19 pandemic: Delayed medical care.
During the COVID-19 pandemic, emergency room visits have drastically decreased for non-COVID conditions such as appendicitis, heart attack, and stroke. Patients may be avoiding seeking medical attention for fear of catching the deadly condition or as an unintended consequence of stay-at-home orders. This delay in seeki...
covid-19;coronary artery disease;postinfarction ventricular septal defect
Case Reports
Masroor, Saqib
10.1111/jocs.14638
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Collateral damage of COVID-19 pandemic: Delayed medical care. [Abstract]: During the COVID-19 pandemic, emergency room visits have drastically decreased for non-COVID conditions such as appendicitis, heart attack, and stroke. Patients may be avoiding seeking medical attention for fear of catching the deadly co...
32,618,332
J Public Health (Oxf)
Emerging public health challenge in UK: perception and belief on increased COVID19 death among BAME healthcare workers.
BACKGROUND: Coronavirus infection Disease 19 impacted every part of the world and routine life. Recent report from the Office of national statistics in UK reported disproportionate death among Black Asian and minority ethnic (BAME) population. NHS is heavily relied on the BAME work force both in front line and in the c...
bame group;bame health workers;covid 19;death;healthcare workers
Journal Article
Moorthy, Arumugam;Sankar, Thangasamy K
10.1093/pubmed/fdaa096
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emerging public health challenge in UK: perception and belief on increased COVID19 death among BAME healthcare workers. [Abstract]: BACKGROUND: Coronavirus infection Disease 19 impacted every part of the world and routine life. Recent report from the Office of national statistics in UK reported disproportionat...
32,571,612
Nutr Metab Cardiovasc Dis
Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease.
AIMS: CoV-19/SARS-CoV-2 is a highly pathogenic virus that is causing a global pandemic with a high number of deaths and infected people. To contain the diffusion of infection, several governments have enforced restrictions on outdoor activities or even collective quarantine on the population. The present commentary bri...
covid-19;gender;lifestyle;physical activity;quarantine;stress;vitamin d
Journal Article
Mattioli, Anna V;Sciomer, Susanna;Cocchi, Camilla;Maffei, Silvia;Gallina, Sabina
10.1016/j.numecd.2020.05.020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease. [Abstract]: AIMS: CoV-19/SARS-CoV-2 is a highly pathogenic virus that is causing a global pandemic with a high number of deaths and infected people. To contain the diffusion of infection, sev...
32,500,116
AAS Open Res
Leveraging investments in Ebola preparedness for COVID-19 in Sub-Saharan Africa.
The emergence of SARS-CoV-2 in China and transmission to more than 80 territories worldwide, including nine countries in Africa, presents a delicate situation for low-resource settings. Countries in Eastern and Central Africa have been on high alert since mid-2018 in anticipation of regional spread of the Ebola virus f...
covid-19 preparedness;coronavirus;ebola;sars-cov-2
Journal Article
Ayebare, Rodgers;Waitt, Peter;Okello, Stephen;Kayiira, Mubaraka;Atim Ajok, Maureen;Nakatudde, Irene;Bhadelia, Nahid;Lamorde, Mohammed
10.12688/aasopenres.13052.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Leveraging investments in Ebola preparedness for COVID-19 in Sub-Saharan Africa. [Abstract]: The emergence of SARS-CoV-2 in China and transmission to more than 80 territories worldwide, including nine countries in Africa, presents a delicate situation for low-resource settings. Countries in Eastern and Central...
33,078,367
Ann Biomed Eng
Effects of the Lower Airway Secretions on Airway Opening Pressures and Suction Pressures in Critically Ill COVID-19 Patients: A Computational Simulation.
In patients with critically ill COVID-19 pneumonia, lower airways are filled with plenty of highly viscous exudates or mucus, leading to airway occlusion. The estimation of airway opening pressures and effective mucus clearance are therefore two issues that clinicians are most concerned about during mechanical ventilat...
airway mucus;airway opening pressure;coronavirus disease 2019;endotracheal suctioning;respiratory mechanics
Journal Article;Observational Study
Chen, Zhenglong;Zhong, Ming;Jiang, Li;Chen, Nanshan;Tu, Shengjin;Wei, Yuan;Sang, Ling;Zheng, Xia;Zhang, Chunyuan;Tao, Jiale;Deng, Linhong;Song, Yuanlin
10.1007/s10439-020-02648-0
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effects of the Lower Airway Secretions on Airway Opening Pressures and Suction Pressures in Critically Ill COVID-19 Patients: A Computational Simulation. [Abstract]: In patients with critically ill COVID-19 pneumonia, lower airways are filled with plenty of highly viscous exudates or mucus, leading to airway o...
32,125,269
Emerg Infect Dis
Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Shenzhen, China, 2020.
Since early January 2020, after the outbreak of coronavirus infection in Wuhan, China, approximately 365 confirmed cases have been reported in Shenzhen, China. The mode of community and intrafamily transmission is threatening residents in Shenzhen. Strategies to strengthen prevention and interruption of these transmiss...
2019 novel coronavirus;covid-19;china;sars-cov-2;shenzhen;community transmission;coronavirus;epidemiologic;respiratory infections;severe respiratory syndrome coronavirus 2;viruses
Journal Article
Liu, Jiaye;Liao, Xuejiao;Qian, Shen;Yuan, Jing;Wang, Fuxiang;Liu, Yingxia;Wang, Zhaoqin;Wang, Fu-Sheng;Liu, Lei;Zhang, Zheng
10.3201/eid2606.200239
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Shenzhen, China, 2020. [Abstract]: Since early January 2020, after the outbreak of coronavirus infection in Wuhan, China, approximately 365 confirmed cases have been reported in Shenzhen, China. The mode of community and intrafamily tra...
32,153,167
Zhonghua Jie He He Hu Xi Za Zhi
[The differential diagnosis for novel coronavirus pneumonia and similar lung diseases in general hospitals].
Novel coronavirus pneumonia was a novel coronavirus infection that has dominated pulmonary infection since December 2019. The main manifestations were fever, dry cough, shortness of breath, normal or leukopenia in peripheral blood and changes in chest CT and in severe cases, multiple organ failure might occur. The Nati...
clinical features;coronavirus disease 2019;diagnosis, differential;tomography, x-ray computed
Journal Article
Tian, X L;Peng, M;Wang, H P;Cai, B Q;Xu, W B;Zhu, Y J;Li, T S;Zhu, H D;Song, L;Wang, M Z;Zhang, L;Shi, J H
10.3760/cma.j.cn112147-20200221-00136
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [The differential diagnosis for novel coronavirus pneumonia and similar lung diseases in general hospitals]. [Abstract]: Novel coronavirus pneumonia was a novel coronavirus infection that has dominated pulmonary infection since December 2019. The main manifestations were fever, dry cough, shortness of breath, ...
33,067,719
Neuromolecular Med
Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury.
Ergothioneine (ET) is a naturally occurring antioxidant that is synthesized by non-yeast fungi and certain bacteria. ET is not synthesized by animals, including humans, but is avidly taken up from the diet, especially from mushrooms. In the current study, we elucidated the effect of ET on the hCMEC/D3 human brain endot...
7-ketocholesterol;anti-inflammatory;antioxidant;blood-brain barrier;covid-19;cox2;claudin-5;coronavirus;cyclooxygenase;cytokines;eicosanoids;ergothioneine;free radicals;inflammation;mushrooms;nf-kb;oxidative stress;oxysterols;tnf-alpha;tight junction proteins;zo-1
Journal Article;Research Support, Non-U.S. Gov't
Koh, Sally Shuxian;Ooi, Samantha Chia-Yi;Lui, Natalie Man-Yin;Qiong, Cao;Ho, Leona Ting-Yuke;Cheah, Irwin Kee-Mun;Halliwell, Barry;Herr, Deron R;Ong, Wei-Yi
10.1007/s12017-020-08620-4
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury. [Abstract]: Ergothioneine (ET) is a naturally occurring antioxidant that is synthesized by non-yeast fungi and certain bacteria. ET is not synthesized by animals, including humans, but is avidly taken up from the diet, especially from mus...
32,956,612
Emerg Infect Dis
Two Pandemics, One Challenge-Leveraging Molecular Test Capacity of Tuberculosis Laboratories for Rapid COVID-19 Case-Finding.
In many settings, the ongoing coronavirus disease (COVID-19) pandemic coincides with other major public health threats, in particular tuberculosis. Using tuberculosis (TB) molecular diagnostic infrastructure, which has substantially expanded worldwide in recent years, for COVID-19 case-finding might be warranted. We an...
covid-19;pcr;sars-cov-2;bacteria;bacterial infections;coronavirus disease;laboratory;quality control;respiratory infections;severe acute respiratory syndrome coronavirus 2;tuberculosis and other mycobacteria;viruses;zoonoses
Journal Article;Research Support, Non-U.S. Gov't
Homolka, Susanne;Paulowski, Laura;Andres, Sonke;Hillemann, Doris;Jou, Ruwen;Gunther, Gunar;Claassens, Mareli;Kuhns, Martin;Niemann, Stefan;Maurer, Florian P
10.3201/eid2611.202602
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Two Pandemics, One Challenge-Leveraging Molecular Test Capacity of Tuberculosis Laboratories for Rapid COVID-19 Case-Finding. [Abstract]: In many settings, the ongoing coronavirus disease (COVID-19) pandemic coincides with other major public health threats, in particular tuberculosis. Using tuberculosis (TB) m...
32,664,217
Nanomaterials (Basel)
Effects of Airborne Nanoparticles on the Nervous System: Amyloid Protein Aggregation, Neurodegeneration and Neurodegenerative Diseases.
How the environment contributes to neurodegenerative diseases such as Alzheimer's is not well understood. In recent years, science has found augmenting evidence that nano-sized particles generated by transport (e.g., fuel combustion, tire wear and brake wear) may promote Alzheimer's disease (AD). Individuals residing c...
alzheimer's disease;covid-19;caenorhabditis elegans;air pollution;amyloid;dementia;neurotoxicology;particulate matter;serotonin;tire wear
Journal Article;Review
von Mikecz, Anna;Schikowski, Tamara
10.3390/nano10071349
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Effects of Airborne Nanoparticles on the Nervous System: Amyloid Protein Aggregation, Neurodegeneration and Neurodegenerative Diseases. [Abstract]: How the environment contributes to neurodegenerative diseases such as Alzheimer's is not well understood. In recent years, science has found augmenting evidence th...
32,677,721
Transpl Infect Dis
COVID-19 and kidney transplant recipients.
BACKGROUND: The novel coronavirus has become a global threat and healthcare concern. The manifestations of COVID-19 pneumonia in transplant patients are not well understood and may have more severe symptoms, longer duration, and a worse prognosis than in immunocompetent populations. AIMS: This study proposed to evaluat...
covid-19;sars-cov-2;immunosuppression;kidney transplant
Case Reports;Journal Article;Multicenter Study
Abolghasemi, Sara;Mardani, Masoud;Sali, Shahnaz;Honarvar, Negin;Baziboroun, Mana
10.1111/tid.13413
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and kidney transplant recipients. [Abstract]: BACKGROUND: The novel coronavirus has become a global threat and healthcare concern. The manifestations of COVID-19 pneumonia in transplant patients are not well understood and may have more severe symptoms, longer duration, and a worse prognosis than in i...
32,220,284
Lancet Infect Dis
Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study.
BACKGROUND: In December, 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China. The number of affected pregnant women is increasing, but scarce information is available about the clinical features of COVID-19 in pregnancy. This study aim...
Journal Article;Research Support, Non-U.S. Gov't
Yu, Nan;Li, Wei;Kang, Qingling;Xiong, Zhi;Wang, Shaoshuai;Lin, Xingguang;Liu, Yanyan;Xiao, Juan;Liu, Haiyi;Deng, Dongrui;Chen, Suhua;Zeng, Wanjiang;Feng, Ling;Wu, Jianli
10.1016/S1473-3099(20)30176-6
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. [Abstract]: BACKGROUND: In December, 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emer...
32,544,071
J Med Internet Res
Identification of Symptoms Prognostic of COVID-19 Severity: Multivariate Data Analysis of a Case Series in Henan Province.
BACKGROUND: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease (COVID-19), has been declared a global pandemic. Identifying individuals whose infection can potentially become severe is critical to control the case fatality rate of COVID-19. However, knowledge ...
covid-19;cvd;henan province;prognostic symptoms;severity
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Li, Jitian;Chen, Zhe;Nie, Yifei;Ma, Yan;Guo, Qiaoyun;Dai, Xiaofeng
10.2196/19636
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Identification of Symptoms Prognostic of COVID-19 Severity: Multivariate Data Analysis of a Case Series in Henan Province. [Abstract]: BACKGROUND: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease (COVID-19), has been declared a global pandemic. Iden...
33,035,674
Int J Infect Dis
Contact tracing with digital assistance in Taiwan's COVID-19 outbreak response.
AIM: Comprehensive case investigation and contact tracing are crucial to prevent community spread of COVID-19. We demonstrated a utility of using traditional contact tracing measures supplemented with symptom tracking and contact management system to assist public health workers with high efficiency. METHODS: A central...
covid-19;contact tracing;coronavirus;digital tool;outbreak response
Evaluation Study;Journal Article
Jian, Shu-Wan;Cheng, Hao-Yuan;Huang, Xiang-Ting;Liu, Ding-Ping
10.1016/j.ijid.2020.09.1483
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Contact tracing with digital assistance in Taiwan's COVID-19 outbreak response. [Abstract]: AIM: Comprehensive case investigation and contact tracing are crucial to prevent community spread of COVID-19. We demonstrated a utility of using traditional contact tracing measures supplemented with symptom tracking a...
32,772,788
Glob Public Health
Travel restrictions as a disease control measure: Lessons from yellow fever.
Travel restrictions have become a common disease control measure during the 2019 Coronavirus disease pandemic (COVID-19). Measures have ranged from quarantines when entering a country to outright travel bans. Yet more widespread travel restrictions in the form of country vaccine entry requirements have been in place fo...
country vaccine entry requirements;health diplomacy;quarantine;travel restrictions;yellow fever
Historical Article;Journal Article;Research Support, N.I.H., Extramural;Video-Audio Media
Vanderslott, Samantha;Marks, Tatjana
10.1080/17441692.2020.1805786
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Travel restrictions as a disease control measure: Lessons from yellow fever. [Abstract]: Travel restrictions have become a common disease control measure during the 2019 Coronavirus disease pandemic (COVID-19). Measures have ranged from quarantines when entering a country to outright travel bans. Yet more wide...
32,701,120
JAMA Otolaryngol Head Neck Surg
Telemedicine Services Provided to Medicare Beneficiaries by Otolaryngologists Between 2010 and 2018.
Importance: Clinicians are increasingly adopting telemedicine in an effort to expand patient access and efficiently deliver care. However, the extent to which otolaryngologists provide telemedicine services is unclear. Objective: To characterize recent trends in the use of telemedicine by otolaryngologists to deliver c...
Journal Article;Multicenter Study
Miller, Lauren E;Rathi, Vinay K;Kozin, Elliott D;Naunheim, Matthew R;Xiao, Roy;Gray, Stacey T
10.1001/jamaoto.2020.1911
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine Services Provided to Medicare Beneficiaries by Otolaryngologists Between 2010 and 2018. [Abstract]: Importance: Clinicians are increasingly adopting telemedicine in an effort to expand patient access and efficiently deliver care. However, the extent to which otolaryngologists provide telemedicine ...
32,733,711
Case Rep Cardiol
A Steep Increase in the HeartLogic Index Predicts COVID-19 Disease in an Advanced Heart Failure Patient.
We present a patient with severe nonischemic cardiomyopathy in whom the HeartLogic algorithm was activated on her Boston Scientific cardioverter defibrillator. She had an out-of-alert state for several months and had clinically "stable" heart failure with no hospitalizations in the last 6 months. A sudden and fast incr...
Case Reports
Heggermont, Ward;Nguyen, Pham Anh Hong;Lau, Chirik-Wah;Tournoy, Kurt
10.1155/2020/8896152
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Steep Increase in the HeartLogic Index Predicts COVID-19 Disease in an Advanced Heart Failure Patient. [Abstract]: We present a patient with severe nonischemic cardiomyopathy in whom the HeartLogic algorithm was activated on her Boston Scientific cardioverter defibrillator. She had an out-of-alert state for ...
32,571,743
Eur Urol Focus
Prioritising Urological Surgery in the COVID-19 Era: A Global Reflection on Guidelines.
BACKGROUND: Determining whether members follow guidelines, including guidelines prepared to help direct practice management during the coronavirus disease 2019 (COVID-19) pandemic, is an important goal for medical associations. OBJECTIVE: To determine whether practice of urologists is in line with guidelines for the ma...
covid-19;coronavirus;guidelines;pandemic;practice management;severe acute respiratory syndrome coronavirus 2;urology
Journal Article
Gravas, Stavros;Fournier, Georges;Oya, Mototsugu;Summerton, Duncan;Scarpa, Roberto Mario;Chlosta, Piotr;Gkialas, Ioannis;Xie, Li-Ping;Rasyid, Nur;Bolton, Damien;Gomez, Reynaldo;Klotz, Laurence;Kulkarni, Sanjay;Tanguay, Simon;de la Rosette, Jean
10.1016/j.euf.2020.06.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prioritising Urological Surgery in the COVID-19 Era: A Global Reflection on Guidelines. [Abstract]: BACKGROUND: Determining whether members follow guidelines, including guidelines prepared to help direct practice management during the coronavirus disease 2019 (COVID-19) pandemic, is an important goal for medic...
32,363,146
IDCases
COVID-19 Presenting with Seizures.
This case report examines a male with no previous history of seizures initially admitting to the medical service later upgraded to ICU after respiratory failure developing multiple episodes of seizures. Laboratory values on admission, neurological investigations, as well as review of current literature on COVID-19 ence...
covid 19;pandemic;sars;sars cov-2;coronavirus;novel coronavirus
Case Reports
Sohal, Sandeep;Mansur, Mossammat
10.1016/j.idcr.2020.e00782
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 Presenting with Seizures. [Abstract]: This case report examines a male with no previous history of seizures initially admitting to the medical service later upgraded to ICU after respiratory failure developing multiple episodes of seizures. Laboratory values on admission, neurological investigations, ...
32,924,565
Int J Environ Health Res
Trend of COVID-19 spreads and status of household handwashing practice and its determinants in Bangladesh - situation analysis using national representative data.
The objective of the study was to assess the prevalence and factors associated with household (HH) handwashing practice in Bangladesh and draw a trend of COVID-19 spreads and compare that with the countrywide HH handwashing practice. The study is based on the two national representative publicly available datasets (MIC...
bangladesh;covid-19;hand hygiene;households
Journal Article
Ahmed, Md Sabbir;Yunus, Fakir Md
10.1080/09603123.2020.1817343
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Trend of COVID-19 spreads and status of household handwashing practice and its determinants in Bangladesh - situation analysis using national representative data. [Abstract]: The objective of the study was to assess the prevalence and factors associated with household (HH) handwashing practice in Bangladesh an...
32,546,657
J Med Ethics
Triage of critical care resources in COVID-19: a stronger role for justice.
Some ethicists assert that there is a consensus that maximising medical outcomes takes precedence as a principle of resource allocation in emergency triage of absolutely scarce resources. But the nature of the current severe acute respiratory syndrome-related coronavirus 2 pandemic and the history of debate about balan...
distributive justice;public health ethics;resource allocation
Journal Article;Comment
Reid, Lynette
10.1136/medethics-2020-106320
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Triage of critical care resources in COVID-19: a stronger role for justice. [Abstract]: Some ethicists assert that there is a consensus that maximising medical outcomes takes precedence as a principle of resource allocation in emergency triage of absolutely scarce resources. But the nature of the current sever...
32,564,881
Trends Ecol Evol
COVID-19, Health, Conservation, and Shared Wellbeing: Details Matter.
Many have stridently recommended banning markets like the one where coronavirus disease 2019 (COVID-19) originally spread. We highlight that millions of people around the world depend on markets for subsistence and the diverse use of animals globally defies uniform bans. We argue that the immediate and fair priority is...
animals;disease;meat;pandemic;transmission;wildlife;zoonotic
Journal Article
Montgomery, Robert A;Macdonald, David W
10.1016/j.tree.2020.06.001
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: COVID-19, Health, Conservation, and Shared Wellbeing: Details Matter. [Abstract]: Many have stridently recommended banning markets like the one where coronavirus disease 2019 (COVID-19) originally spread. We highlight that millions of people around the world depend on markets for subsistence and the diverse us...
32,668,514
Korean J Intern Med
Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019.
BACKGROUND/AIMS: Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. We sought to determine the utility of lung ultrasound for early detection of pneumonia and for assessment of respiratory failure among patients with coronavirus disease 2019 (COVID-...
covid-19;pneumonia;respiratory insufficiency;severe acute respiratory syndrome coronavirus 2;ultrasonography
Case Reports;Journal Article
Cho, Young-Jae;Song, Kyoung-Ho;Lee, Yunghee;Yoon, Joo Heung;Park, Ji Young;Jung, Jongtak;Lim, Sung Yoon;Lee, Hyunju;Yoon, Ho Il;Park, Kyoung Un;Kim, Hong Bin;Kim, Eu Suk
10.3904/kjim.2020.180
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019. [Abstract]: BACKGROUND/AIMS: Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. We sought to determine the utility of lung u...
32,659,729
Adv Med Sci
Lung ultrasound in the diagnosis of COVID-19 infection - A case series and review of the literature.
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and spreading worldwide has become a serious challenge for the entire health care system as regards infection prevention, rapid diagnosis, and treatment. Lung ultrasound (LUS) is a dynamically developing diagnostic method used in i...
covid-19;coronavirus;lung ultrasound;viral pneumonia
Case Reports;Journal Article;Review
Buda, Natalia;Segura-Grau, Elena;Cylwik, Jolanta;Welnicki, Marcin
10.1016/j.advms.2020.06.005
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Lung ultrasound in the diagnosis of COVID-19 infection - A case series and review of the literature. [Abstract]: COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and spreading worldwide has become a serious challenge for the entire health care system as regards infection...
32,341,078
Clin Med (Lond)
COVID-19 patients presenting with afebrile acute abdominal pain.
IMPORTANCE: With the surge in COVID-19 cases worldwide, the medical community should be aware of atypical clinical presentations to help with correct diagnosis, to take the proper measures to place the patient in isolation and to avoid healthcare professionals being infected by coronavirus (SARS-CoV-2). OBJECTIVE: To r...
covid-19;abdominal pain;afebrile;atypical presentation;computed tomography
Journal Article
Gahide, Gerald;Frandon, Julien;Vendrell, Jean-Francois
10.7861/clinmed.2020-0150
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 patients presenting with afebrile acute abdominal pain. [Abstract]: IMPORTANCE: With the surge in COVID-19 cases worldwide, the medical community should be aware of atypical clinical presentations to help with correct diagnosis, to take the proper measures to place the patient in isolation and to avoi...
32,234,126
Zhonghua Liu Xing Bing Xue Za Zhi
[An epidemiologic thinking on the diagnosis criteria of COVID-19].
The diagnosis of COVID-19 is based on the positive of etiological test. The current etiological test of COVID-19 cost long time, and have high false negative rate, may resulting delay the measures of disease treatment and prevention. We suggested that COVID-19 should be diagnosed as 3 types: suspected case, clinical di...
covid-19;diagnosis criteria;false negative
Journal Article
Tan, H Z
10.3760/cma.j.cn112338-20200226-00181
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [An epidemiologic thinking on the diagnosis criteria of COVID-19]. [Abstract]: The diagnosis of COVID-19 is based on the positive of etiological test. The current etiological test of COVID-19 cost long time, and have high false negative rate, may resulting delay the measures of disease treatment and prevention...
33,075,406
J Hosp Infect
Use, re-use or discard? Quantitatively defined variance in the functional integrity of N95 respirators following vaporized hydrogen peroxide decontamination during the COVID-19 pandemic.
BACKGROUND: Coronavirus disease 2019 has stretched the ability of many institutions to supply needed personal protective equipment, especially N95 respirators. N95 decontamination and re-use programmes provide one potential solution to this problem. Unfortunately, a comprehensive evaluation of the effects of decontamin...
covid-19;decontamination;n95;quantitative fit test;respirator
Journal Article
Levine, C;Grady, C;Block, T;Hurley, H;Russo, R;Peixoto, B;Frees, A;Ruiz, A;Alland, D
10.1016/j.jhin.2020.10.007
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Use, re-use or discard? Quantitatively defined variance in the functional integrity of N95 respirators following vaporized hydrogen peroxide decontamination during the COVID-19 pandemic. [Abstract]: BACKGROUND: Coronavirus disease 2019 has stretched the ability of many institutions to supply needed personal pr...
33,055,034
IEEE Trans Vis Comput Graph
Modeling in the Time of COVID-19: Statistical and Rule-based Mesoscale Models.
We present a new technique for the rapid modeling and construction of scientifically accurate mesoscale biological models. The resulting 3D models are based on a few 2D microscopy scans and the latest knowledge available about the biological entity, represented as a set of geometric relationships. Our new visual-progra...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Nguyen, Ngan;Strnad, Ondrej;Klein, Tobias;Luo, Deng;Alharbi, Ruwayda;Wonka, Peter;Maritan, Martina;Mindek, Peter;Autin, Ludovic;Goodsell, David S;Viola, Ivan
10.1109/TVCG.2020.3030415
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Modeling in the Time of COVID-19: Statistical and Rule-based Mesoscale Models. [Abstract]: We present a new technique for the rapid modeling and construction of scientifically accurate mesoscale biological models. The resulting 3D models are based on a few 2D microscopy scans and the latest knowledge available...
32,967,691
Global Health
Using volunteered geographic information to assess mobility in the early phases of the COVID-19 pandemic: a cross-city time series analysis of 41 cities in 22 countries from March 2nd to 26th 2020.
OBJECTIVES: Restricting mobility is a central aim for lowering contact rates and preventing COVID-19 transmission. Yet the impact on mobility of different non-pharmaceutical countermeasures in the earlier stages of the pandemic is not well-understood. DESIGN: Trends were evaluated using Citymapper's mobility index cove...
Journal Article;Research Support, Non-U.S. Gov't
Vannoni, Matia;McKee, Martin;Semenza, Jan C;Bonell, Chris;Stuckler, David
10.1186/s12992-020-00598-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Using volunteered geographic information to assess mobility in the early phases of the COVID-19 pandemic: a cross-city time series analysis of 41 cities in 22 countries from March 2nd to 26th 2020. [Abstract]: OBJECTIVES: Restricting mobility is a central aim for lowering contact rates and preventing COVID-19 ...
32,769,401
Cardiol Rev
Chloroquine or Hydroxychloroquine for Management of Coronavirus Disease 2019: Friend or Foe?
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a threat to the health of many humans across the world as they confront coronavirus disease 2019 (COVID-19). Previous promising in vitro data that emerged after the SARS-CoV outbreak in 2003, along with the emergent need for pharmacologic mana...
Journal Article
Schluenz, Lauren A;Ramos-Otero, Gerardo P;Nawarskas, James J
10.1097/CRD.0000000000000329
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Chloroquine or Hydroxychloroquine for Management of Coronavirus Disease 2019: Friend or Foe? [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a threat to the health of many humans across the world as they confront coronavirus disease 2019 (COVID-19). Previous promising i...
32,404,257
Gac Sanit
[Measures to contain gender-based violence during the COVID-19 pandemic].
Crises, emergencies and times of unrest have been linked to increased interpersonal violence, including violence against women. Following the declaration of alarm status and quarantine, different measures have been implemented to mitigate the possible effect of gender violence (Contingency Plan against Gender-Based Vio...
covid-19 pandemic;cuarentena;intimate partner violence;pandemia de covid-19;quarantine;violencia de companero intimo
English Abstract;Journal Article
Ruiz-Perez, Isabel;Pastor-Moreno, Guadalupe
10.1016/j.gaceta.2020.04.005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Measures to contain gender-based violence during the COVID-19 pandemic]. [Abstract]: Crises, emergencies and times of unrest have been linked to increased interpersonal violence, including violence against women. Following the declaration of alarm status and quarantine, different measures have been implemente...
32,700,795
ChemMedChem
Targeting SARS-CoV-2 RBD Interface: a Supervised Computational Data-Driven Approach to Identify Potential Modulators.
Coronavirus disease 2019 (COVID-19) has spread out as a pandemic threat affecting over 2 million people. The infectious process initiates via binding of SARS-CoV-2 Spike (S) glycoprotein to host angiotensin-converting enzyme 2 (ACE2). The interaction is mediated by the receptor-binding domain (RBD) of S glycoprotein, p...
covid-19;docking;molecular dynamics;pharmacophore;protein-protein interactions
Journal Article
Gulotta, Maria Rita;Lombino, Jessica;Perricone, Ugo;De Simone, Giada;Mekni, Nedra;De Rosa, Maria;Diana, Patrizia;Padova, Alessandro
10.1002/cmdc.202000259
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Targeting SARS-CoV-2 RBD Interface: a Supervised Computational Data-Driven Approach to Identify Potential Modulators. [Abstract]: Coronavirus disease 2019 (COVID-19) has spread out as a pandemic threat affecting over 2 million people. The infectious process initiates via binding of SARS-CoV-2 Spike (S) glycopr...
32,395,487
Ann Transl Med
Clinical characteristics of Coronavirus Disease 2019 and development of a prediction model for prolonged hospital length of stay.
Background: The epidemic of Coronavirus Disease 2019 (COVID-19) has become a global health emergency, but the clinical characteristics of COVID-19 are not fully described. We aimed to describe the clinical characteristics of COVID-19 outside of Wuhan city; and to develop a multivariate model to predict the risk of prol...
novel coronavirus;clinical characteristics;cost;length of stay (los);prediction
Journal Article
Hong, Yucai;Wu, Xinhu;Qu, Jijing;Gao, Yuandi;Chen, Hao;Zhang, Zhongheng
10.21037/atm.2020.03.147
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of Coronavirus Disease 2019 and development of a prediction model for prolonged hospital length of stay. [Abstract]: Background: The epidemic of Coronavirus Disease 2019 (COVID-19) has become a global health emergency, but the clinical characteristics of COVID-19 are not fully describe...
32,948,888
Wien Klin Wochenschr
SARS-CoV-2: recommendations for treatment in intensive care medicine.
Coronavirus disease 2019 (COVID-19) progresses mildly in most of the cases; however, about 5% of the patients develop a severe acute respiratory distress syndrome (ARDS). Of all COVID-19 patients 3% need intensive care treatment, which becomes a great challenge for anesthesiology and intensive care medicine, medically,...
ards;covid-19;personal protective equipment;respiratory therapy;sars-cov2
Journal Article
Kostenberger, Markus;Hasibeder, Walter;Dankl, Daniel;Germann, Reinhard;Hormann, Christoph;Joannidis, Michael;Markstaller, Klaus;Muller-Muttonen, Steve-Oliver;Neuwersch-Sommeregger, Stefan;Schaden, Eva;Staudinger, Thomas;Ullrich, Roman;Valentin, Andreas;Likar, Rudolf
10.1007/s00508-020-01734-6
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2: recommendations for treatment in intensive care medicine. [Abstract]: Coronavirus disease 2019 (COVID-19) progresses mildly in most of the cases; however, about 5% of the patients develop a severe acute respiratory distress syndrome (ARDS). Of all COVID-19 patients 3% need intensive care treatment,...
32,802,902
Mol Biol Res Commun
Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity.
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China threatened humankind worldwide. The coronaviruses contains the largest RNA genome among all other known RNA viruses, therefore the disease etiology can be understood by analyzing the genome sequence of SARS-CoV-2. In this stud...
covid-19;coronavirus;gene silencing;microrna;pathways;target
Journal Article
Saini, Sandeep;Saini, Avneet;Thakur, Chander Jyoti;Kumar, Varinder;Gupta, Rishabh Dilip;Sharma, Jogesh Kumar
10.22099/mbrc.2020.36507.1487
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity. [Abstract]: The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China threate...
32,919,072
Clin Microbiol Infect
Detection and infectivity potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) environmental contamination in isolation units and quarantine facilities.
OBJECTIVES: Environmental surfaces have been suggested as likely contributors in the transmission of COVID-19. This study assessed the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contaminating surfaces and objects in two hospital isolation units and a quarantine hotel. METHODS: SARS-CoV-...
covid-19;contamination;coronavirus;sars-cov-2;surface;viability
Journal Article
Ben-Shmuel, Amir;Brosh-Nissimov, Tal;Glinert, Itai;Bar-David, Elad;Sittner, Assa;Poni, Reut;Cohen, Regev;Achdout, Hagit;Tamir, Hadas;Yahalom-Ronen, Yfat;Politi, Boaz;Melamed, Sharon;Vitner, Einat;Cherry, Lilach;Israeli, Ofir;Beth-Din, Adi;Paran, Nir;Israely, Tomer;Yitzhaki, Shmuel;Levy, Haim;Weiss, Shay
10.1016/j.cmi.2020.09.004
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Detection and infectivity potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) environmental contamination in isolation units and quarantine facilities. [Abstract]: OBJECTIVES: Environmental surfaces have been suggested as likely contributors in the transmission of COVID-19. This study ass...
32,724,866
Contemp Clin Trials Commun
Pragmatic, adaptive clinical trials: Is 2020 the dawning of a new age?
Given the high case fatality rate of SARS-CoV-2, for which there is no cure and no vaccine, clinicians are forced to make decisions about how best to manage patients with limited high-quality evidence to guide treatment. Traditional randomized controlled trials provide strong experimental evidence, however, tend to be ...
Journal Article
Branch-Elliman, Westyn;Lehmann, Lisa Soleymani;Boden, William E;Ferguson, Ryan;Monach, Paul
10.1016/j.conctc.2020.100614
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pragmatic, adaptive clinical trials: Is 2020 the dawning of a new age? [Abstract]: Given the high case fatality rate of SARS-CoV-2, for which there is no cure and no vaccine, clinicians are forced to make decisions about how best to manage patients with limited high-quality evidence to guide treatment. Traditi...
32,505,980
Diabetes Metab Syndr
Relationship between COVID-19 and obesity.
N/A.
covid-19;obesity;renin-angiotensin system;sarcopenia;sleep apnea;vitamin d deficiency
Letter
Ekiz, Timur;Pazarli, Ahmet Cemal
10.1016/j.dsx.2020.05.047
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Relationship between COVID-19 and obesity. [Abstract]: N/A. [Keywords]: covid-19;obesity;renin-angiotensin system;sarcopenia;sleep apnea;vitamin d deficiency
33,061,288
Clin Ophthalmol
The Role of the Ocular Tissue in SARS-CoV-2 Transmission.
The current global pandemic of coronavirus disease 2019 (COVID-19) has affected over 21 million people and caused over half a million deaths within a few months. COVID-19 has become one of the most severe public health crises in recent years. Compared to other pathogenic coronaviruses, the severe acute respiratory synd...
ace2;covid-19;sars-cov-2;eye;transmission
Journal Article;Review
Peng, Michael;Dai, Jiannong;Sugali, Chenna Kesavulu;Rayana, Naga Pradeep;Mao, Weiming
10.2147/OPTH.S269868
[ 0, 1, 0, 1, 1, 0, 0 ]
[Title]: The Role of the Ocular Tissue in SARS-CoV-2 Transmission. [Abstract]: The current global pandemic of coronavirus disease 2019 (COVID-19) has affected over 21 million people and caused over half a million deaths within a few months. COVID-19 has become one of the most severe public health crises in recent years...
32,391,657
Zhejiang Da Xue Xue Bao Yi Xue Ban
[Diagnosis and treatment recommendation for pediatric COVID-19 (the second edition)].
The coronavirus disease 2019 (COVID-19) has caused a global pandemic. All people including children are generally susceptible to COVID-19, but the condition is relatively mild for children. The diagnosis of COVID-19 is largely based on the epidemiological evidence and clinical manifestations, and confirmed by positive ...
Journal Article
Chen, Zhimin;Fu, Junfen;Shu, Qiang;Wang, Wei;Chen, Yinghu;Hua, Chunzhen;Li, Fubang;Lin, Ru;Tang, Lanfang;Wang, Tianlin;Wang, Yingshuo;Xu, Weize;Yang, Zihao;Ye, Sheng;Yuan, Tianming;Zhang, Chenmei;Zhang, Yuanyuan
10.3785/j.issn.1008-9292.2020.02.01
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [Diagnosis and treatment recommendation for pediatric COVID-19 (the second edition)]. [Abstract]: The coronavirus disease 2019 (COVID-19) has caused a global pandemic. All people including children are generally susceptible to COVID-19, but the condition is relatively mild for children. The diagnosis of COVID-...
32,999,777
Cureus
Role of Biochemical Markers in Invasive Ventilation of Coronavirus Disease 2019 Patients: Multinomial Regression and Survival Analysis.
Background and objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic. The disease mainly affects the respiratory system of the patient, in particular, the lungs, which leads to patients presenting with acute respiratory d...
coronavirus;covid-19;infectious diseases;invasive;mortality;non-invasive;pakistan;pulmonology;ventilation;ventilator
Journal Article
Asghar, Muhammad Sohaib;Haider Kazmi, Syed J;Khan, Noman A;Akram, Mohammed;Jawed, Rumael;Rafaey, Wania;Hassan, Maira;Rasheed, Uzma;Khan, Mehak;Khan, Ali R
10.7759/cureus.10054
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Role of Biochemical Markers in Invasive Ventilation of Coronavirus Disease 2019 Patients: Multinomial Regression and Survival Analysis. [Abstract]: Background and objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pand...
32,924,854
Telemed J E Health
Preserving Multidisciplinary Care Model and Patient Safety During Reopening of Ambulatory Cystic Fibrosis Clinic for Nonurgent Care: A Hybrid Telehealth Model.
Introduction: The University of Virginia's (UVA's) adult cystic fibrosis (CF) program implemented a rapid and successful transition to telemedicine care mid-March of 2020 in response to the coronavirus disease 2019 (COVID-19) pandemic. In May 2020, the adult UVA CF program redesigned the care model to adjust to the reo...
covid-19;cystic fibrosis;e-health;pandemic;telehealth;telemedicine
Journal Article;Research Support, Non-U.S. Gov't
List, Rhonda;Compton, Martina;Soper, Morgan;Bruschwein, Heather;Gettle, Lucy;Bailey, Molly;Starheim, Elissa;Kalmanek, John;Somerville, Lindsay;Albon, Dana
10.1089/tmj.2020.0247
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Preserving Multidisciplinary Care Model and Patient Safety During Reopening of Ambulatory Cystic Fibrosis Clinic for Nonurgent Care: A Hybrid Telehealth Model. [Abstract]: Introduction: The University of Virginia's (UVA's) adult cystic fibrosis (CF) program implemented a rapid and successful transition to tele...
32,442,333
Transfusion
Estimation of the number of blood donors during the COVID-19 incubation period across China and analysis of prevention and control measures for blood transfusion transmission.
BACKGROUND: The aim of this study was to estimate the number of blood donors during the COVID-19 incubation period across China. STUDY DESIGN AND METHODS: In this study, we developed a predictive model to estimate the number of blood donors during the COVID-19 incubation period among 34 provincial regions in China. Our...
Journal Article
Yuan, Zhaohu;Chen, Dandan;Chen, Xiaojie;Wei, Yaming
10.1111/trf.15858
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Estimation of the number of blood donors during the COVID-19 incubation period across China and analysis of prevention and control measures for blood transfusion transmission. [Abstract]: BACKGROUND: The aim of this study was to estimate the number of blood donors during the COVID-19 incubation period across C...
32,737,833
Infection
Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases.
Novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) became pandemic by the end of March 2020. In contrast to the 2002-2003 SARS-CoV outbreak, which had a higher pathogenicity and lead to higher mortality rates, SARSCoV-2 infection appears to be much more contagious. Moreover, many SARS-CoV-2 infected pat...
coronavirus;furin;receptor binding domain;sars-cov;sars-cov-2
Journal Article;Review
Rossi, Giovanni A;Sacco, Oliviero;Mancino, Enrica;Cristiani, Luca;Midulla, Fabio
10.1007/s15010-020-01486-5
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. [Abstract]: Novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) became pandemic by the end of March 2020. In contrast to the ...
32,920,234
Int J Infect Dis
COVID-19: Poor outcomes in patients with zinc deficiency.
BACKGROUND: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19). However, we do not know the clinical significance of serum Zinc levels in COVID-19 patients. The aim of this study was to determine the clinical significanc...
covid-19;sars-cov-2;zinc
Journal Article;Observational Study
Jothimani, Dinesh;Kailasam, Ezhilarasan;Danielraj, Silas;Nallathambi, Balaji;Ramachandran, Hemalatha;Sekar, Padmini;Manoharan, Shruthi;Ramani, Vidyalakshmi;Narasimhan, Gomathy;Kaliamoorthy, Ilankumaran;Rela, Mohamed
10.1016/j.ijid.2020.09.014
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Poor outcomes in patients with zinc deficiency. [Abstract]: BACKGROUND: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19). However, we do not know the clinical significance of serum Zinc levels in COV...
33,073,699
J Biomol Struct Dyn
Antiviral activity of traditional medicinal plants from Ayurveda against SARS-CoV-2 infection.
SARS-CoV-2 is the etiological agent of COVID-19 and responsible for more than 6 million cases globally, for which no vaccine or antiviral is available. Therefore, this study was planned to investigate the antiviral role of the active constituents against spike glycoprotein of SARS-CoV-2 as well as its host ACE2 recepto...
ayurveda;covid-19;sars-cov-2;attachment inhibitor;gene network analysis;pharmacokinetics;structure-based drug design;target prediction
Journal Article
Maurya, Vimal K;Kumar, Swatantra;Bhatt, Madan L B;Saxena, Shailendra K
10.1080/07391102.2020.1832577
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Antiviral activity of traditional medicinal plants from Ayurveda against SARS-CoV-2 infection. [Abstract]: SARS-CoV-2 is the etiological agent of COVID-19 and responsible for more than 6 million cases globally, for which no vaccine or antiviral is available. Therefore, this study was planned to investigate the...
32,645,478
Travel Med Infect Dis
Hydroxychloroquine safety: A meta-analysis of randomized controlled trials.
BACKGROUND: Hydroxychloroquine (HCQ) is currently being examined for COVID-19. No previous meta-analysis has evaluated its side effects versus placebo. We conducted this meta-analysis to compare the safety of HCQ versus placebo. METHODS: Two authors independently searched PubMed and EMBASE databases for randomized cont...
adverse reaction;covid-19;chloroquine;hydroxychloroquine;hyperpigmentation;systematic review
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't
Eljaaly, Khalid;Alireza, Kasim Huseein;Alshehri, Samah;Al-Tawfiq, Jaffar A
10.1016/j.tmaid.2020.101812
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine safety: A meta-analysis of randomized controlled trials. [Abstract]: BACKGROUND: Hydroxychloroquine (HCQ) is currently being examined for COVID-19. No previous meta-analysis has evaluated its side effects versus placebo. We conducted this meta-analysis to compare the safety of HCQ versus pla...
32,839,666
EPMA J
COVID-19 what have we learned? The rise of social machines and connected devices in pandemic management following the concepts of predictive, preventive and personalized medicine.
Objectives: Review, compare and critically assess digital technology responses to the COVID-19 pandemic around the world. The specific point of interest in this research is on predictive, preventive and personalized interoperable digital healthcare solutions. This point is supported by failures from the past, where the...
covid-19;civic technology;digital democracy platform;digital epidemic control;disease management;global pandemic;infection spread;internet of things;monitoring;predictive preventive personalized medicine (3 pm / pppm);predictive, preventive and personalized digital healthcare;professional network;risk assessment;smartp...
Journal Article;Review
Radanliev, Petar;De Roure, David;Walton, Rob;Van Kleek, Max;Montalvo, Rafael Mantilla;Santos, Omar;Maddox, La'Treall;Cannady, Stacy
10.1007/s13167-020-00218-x
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 what have we learned? The rise of social machines and connected devices in pandemic management following the concepts of predictive, preventive and personalized medicine. [Abstract]: Objectives: Review, compare and critically assess digital technology responses to the COVID-19 pandemic around the worl...
32,476,586
J Aging Soc Policy
Meeting the Transitional Care Needs of Older Adults with COVID-19.
Older adults with COVID-19 who survive hospitalizations and return to their homes confront substantial health challenges and an unpredictable future. While understanding of the unique needs of COVID-19 survivors is developing, components of the evidence-based Transitional Care Model provide a framework for taking a mor...
covid-19;transitional care;family caregivers;older adults
Journal Article
Naylor, Mary D;Hirschman, Karen B;McCauley, Kathleen
10.1080/08959420.2020.1773189
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Meeting the Transitional Care Needs of Older Adults with COVID-19. [Abstract]: Older adults with COVID-19 who survive hospitalizations and return to their homes confront substantial health challenges and an unpredictable future. While understanding of the unique needs of COVID-19 survivors is developing, compo...
32,585,913
Vaccines (Basel)
SARS-CoV-2: An Update on Potential Antivirals in Light of SARS-CoV Antiviral Drug Discoveries.
Coronaviruses (CoVs) are a group of RNA viruses that are associated with different diseases in animals, birds, and humans. Human CoVs (HCoVs) have long been known to be the causative agents of mild respiratory illnesses. However, two HCoVs associated with severe respiratory diseases are Severe Acute Respiratory Syndrom...
2019-ncov;covid-19;sars-cov;sars-cov-2;antibodies;antivirals
Journal Article;Review
Elshabrawy, Hatem A
10.3390/vaccines8020335
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2: An Update on Potential Antivirals in Light of SARS-CoV Antiviral Drug Discoveries. [Abstract]: Coronaviruses (CoVs) are a group of RNA viruses that are associated with different diseases in animals, birds, and humans. Human CoVs (HCoVs) have long been known to be the causative agents of mild respir...
32,426,285
Front Oncol
Coronavirus: Older Persons With Cancer in Italy in the COVID-19 Pandemic.
Italy is the European country that was hit first and hardest by the COVID-19 epidemic. Since February 2020, the outbreak of the epidemic disease in Italy, with fatal outcomes in up to 10% of cases, made it urgent to implement extraordinary measures to avoid a breakdown of the universal Italian national health system. T...
covid-19;italy;cancer patients;elderly;pandemic
Journal Article
Fratino, Lucia;Procopio, Giuseppe;Di Maio, Massimo;Cinieri, Saverio;Leo, Silvana;Beretta, Giordano
10.3389/fonc.2020.00648
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus: Older Persons With Cancer in Italy in the COVID-19 Pandemic. [Abstract]: Italy is the European country that was hit first and hardest by the COVID-19 epidemic. Since February 2020, the outbreak of the epidemic disease in Italy, with fatal outcomes in up to 10% of cases, made it urgent to implement...
32,838,945
Virology
Growth, detection, quantification, and inactivation of SARS-CoV-2.
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is the agent responsible for the coronavirus disease 2019 (COVID-19) global pandemic. SARS-CoV-2 is closely related to SARS-CoV, which caused the 2003 SARS outbreak. Although numerous reagents were developed to study SARS-CoV infections, few have been applicabl...
coronavirus;flow cytometry;focus-forming assay;plaque assay;sars-cov-2;titration;virus inactivation
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Case, James Brett;Bailey, Adam L;Kim, Arthur S;Chen, Rita E;Diamond, Michael S
10.1016/j.virol.2020.05.015
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Growth, detection, quantification, and inactivation of SARS-CoV-2. [Abstract]: Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is the agent responsible for the coronavirus disease 2019 (COVID-19) global pandemic. SARS-CoV-2 is closely related to SARS-CoV, which caused the 2003 SARS outbreak. Althoug...
32,691,004
IDCases
Acute abdomen -like-presentation associated with SARS-CoV-2 infection.
As the cases of COVID-19 are flooding around the world, atypical presentations are being recognized, making the diagnosis challenging. Gastrointestinal symptoms and mild abdominal pain are common. However, severe abdominal pain associated with COVID-19 warranting surgical evaluation has been rarely described; recognizi...
acute abdomen;covid-19;pancreatitis;peritonitis;sars-cov-2
Case Reports
Ahmed, Ashraf Omer Elamin;Mohamed, Sara F;Saleh, Ahmed O;Al-Shokri, Shaikha D;Ahmed, Khalid;Mohamed, Mouhand F H
10.1016/j.idcr.2020.e00895
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Acute abdomen -like-presentation associated with SARS-CoV-2 infection. [Abstract]: As the cases of COVID-19 are flooding around the world, atypical presentations are being recognized, making the diagnosis challenging. Gastrointestinal symptoms and mild abdominal pain are common. However, severe abdominal pain ...
32,624,085
Disaster Med Public Health Prep
Protection and Response of a Tertiary Hospital in South Korea to the COVID-19 Outbreak.
OBJECTIVE: Here, we present an overview of how a tertiary hospital responded to maintain necessary activities and protect patients and staff from the coronavirus disease (COVID-19) outbreak. METHODS: Gil Medical Center, a tertiary hospital in Incheon, has operated a special response team since January 21, 2020. All vis...
covid-19;south korea;protection;response;tertiary hospital
Journal Article
Shi, Hye Jin;Lee, Jae Back;Choi, Min Kyung;Jang, Young-Rock;Cho, Yong-Kyun;Eom, Joong Sik
10.1017/dmp.2020.199
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Protection and Response of a Tertiary Hospital in South Korea to the COVID-19 Outbreak. [Abstract]: OBJECTIVE: Here, we present an overview of how a tertiary hospital responded to maintain necessary activities and protect patients and staff from the coronavirus disease (COVID-19) outbreak. METHODS: Gil Medical...
32,599,201
World Neurosurg
Tracking the Volume of Neurosurgical Care During the Coronavirus Disease 2019 Pandemic.
OBJECTIVE: In the present study, we quantified the effect of the coronavirus disease 2019 (COVID-19) on the volume of adult and pediatric neurosurgical procedures, inpatient consultations, and clinic visits at an academic medical center. METHODS: Neurosurgical procedures, inpatient consultations, and outpatient appoint...
covid-19;elective surgery;neurological surgery;sars-cov-2;telehealth;trauma
Journal Article
Patel, Pious D;Kelly, Katherine A;Reynolds, Rebecca A;Turer, Robert W;Salwi, Sanjana;Rosenbloom, S Trent;Bonfield, Christopher M;Naftel, Robert P
10.1016/j.wneu.2020.06.176
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Tracking the Volume of Neurosurgical Care During the Coronavirus Disease 2019 Pandemic. [Abstract]: OBJECTIVE: In the present study, we quantified the effect of the coronavirus disease 2019 (COVID-19) on the volume of adult and pediatric neurosurgical procedures, inpatient consultations, and clinic visits at a...
32,512,263
Semin Arthritis Rheum
COVID-19 in rheumatic disease patients on immunosuppressive agents.
OBJECTIVE: To analyze clinical characteristics and outcome of COVID-19 patients with underlying rheumatic diseases (RD) on immunosuppressive agents. METHOD: A case series of COVID-19 patients with RD on disease modifying anti-rheumatic drugs (DMARDs) were studied by a retrospective chart review. A literature search ide...
biologics;covid-19;dmards;rheumatic disease;sars cov-2
Journal Article
Sharmeen, Saika;Elghawy, Ahmed;Zarlasht, Fnu;Yao, Qingping
10.1016/j.semarthrit.2020.05.010
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in rheumatic disease patients on immunosuppressive agents. [Abstract]: OBJECTIVE: To analyze clinical characteristics and outcome of COVID-19 patients with underlying rheumatic diseases (RD) on immunosuppressive agents. METHOD: A case series of COVID-19 patients with RD on disease modifying anti-rheum...
32,977,781
BMC Med Educ
Pre-graduation medical training including virtual reality during COVID-19 pandemic: a report on students' perception.
BACKGROUND: The Coronavirus Disease 19 (COVID-19) pandemic brought significant disruption to in-hospital medical training. Virtual reality simulating the clinical environment has the potential to overcome this issue and can be particularly useful to supplement the traditional in-hospital medical training during the COV...
covid-19;medical students;simulation training;undergraduate medical education;virtual reality
Journal Article
De Ponti, Roberto;Marazzato, Jacopo;Maresca, Andrea M;Rovera, Francesca;Carcano, Giulio;Ferrario, Marco M
10.1186/s12909-020-02245-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pre-graduation medical training including virtual reality during COVID-19 pandemic: a report on students' perception. [Abstract]: BACKGROUND: The Coronavirus Disease 19 (COVID-19) pandemic brought significant disruption to in-hospital medical training. Virtual reality simulating the clinical environment has th...
32,430,621
Neurol Sci
An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID).
Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropism of the SARS-COV-2 virus, as previously demonstrated for other coronaviruses. We report here the description of a multicenter retrospective-prospe...
covid-19;neurocovid;neurological manifestations;observational study
Clinical Trial;Journal Article;Multicenter Study;Observational Study
Ferrarese, Carlo;Silani, Vincenzo;Priori, Alberto;Galimberti, Stefania;Agostoni, Elio;Monaco, Salvatore;Padovani, Alessandro;Tedeschi, Gioacchino
10.1007/s10072-020-04450-1
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID). [Abstract]: Neurological manifestations of COVID-19 have been described in both single case reports and retrospective scanty case series. They may be linked to the potential neurotropis...
32,746,612
Am J Rhinol Allergy
The Prevalence of Olfactory Dysfunction in the General Population: A Systematic Review and Meta-analysis.
BACKGROUND: Olfactory dysfunction (OD) is common and has been reported as an early indicator of COVID-19. However, the reported prevalence of OD in the general population varies widely depending upon the metric used to assess olfaction.Methodology/Principal: To perform a systematic review and meta-analysis of the preva...
covid-19;anosmia;dysosmia;hyposmia;olfaction;prevalence;smell
Journal Article;Meta-Analysis;Systematic Review
Desiato, Vincent M;Levy, Dylan A;Byun, Young Jae;Nguyen, Shaun A;Soler, Zachary M;Schlosser, Rodney J
10.1177/1945892420946254
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Prevalence of Olfactory Dysfunction in the General Population: A Systematic Review and Meta-analysis. [Abstract]: BACKGROUND: Olfactory dysfunction (OD) is common and has been reported as an early indicator of COVID-19. However, the reported prevalence of OD in the general population varies widely dependin...
32,848,492
Adv Med Educ Pract
Managing Resident Workforce and Residency Training During COVID-19 Pandemic: Scoping Review of Adaptive Approaches.
Objective: To review available adaptive residency training approaches and management of the resident workforce in different residency programs amid COVID-19 pandemic. Materials and Methods: Websites of different professional associations and international or national specialty accreditation institutions were searched. ...
covid-19;sars-cov-2;accreditation;clinical;didactic;residency;surgery
Journal Article;Review
Tolu, Lemi Belay;Feyissa, Garumma Tolu;Ezeh, Alex;Gudu, Wondimu
10.2147/AMEP.S262369
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Managing Resident Workforce and Residency Training During COVID-19 Pandemic: Scoping Review of Adaptive Approaches. [Abstract]: Objective: To review available adaptive residency training approaches and management of the resident workforce in different residency programs amid COVID-19 pandemic. Materials and Me...
32,424,503
Neurol Sci
Potential neurological impact of coronaviruses: implications for the novel SARS-CoV-2.
Coronaviruses (CoV) are viruses widely known to cause severe respiratory distress due to the prominent clinical symptoms presented. These symptoms, which include fever and dry cough, are frequently found in individuals with CoV infection. Neurological manifestations of CoV have often been neglected; however, recent stu...
brain;covid-19;coronavirus;neurologic;sars
Journal Article;Review
Iroegbu, Joy D;Ifenatuoha, Chibuzor W;Ijomone, Omamuyovwi M
10.1007/s10072-020-04469-4
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential neurological impact of coronaviruses: implications for the novel SARS-CoV-2. [Abstract]: Coronaviruses (CoV) are viruses widely known to cause severe respiratory distress due to the prominent clinical symptoms presented. These symptoms, which include fever and dry cough, are frequently found in indiv...
32,653,015
Crit Care
Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis.
BACKGROUND: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak is spreading worldwide. To date, no specific treatment has convincingly demonstrated its efficacy. Hydroxychloroquine and lopinavir/ritonavir have potential interest, but virological and clinical data are scarce, especially in critica...
hydroxychloroquine;intensive care unit;lopinavir/ritonavir;sars-cov-2;standard of care
Comparative Study;Journal Article
Lecronier, Marie;Beurton, Alexandra;Burrel, Sonia;Haudebourg, Luc;Deleris, Robin;Le Marec, Julien;Virolle, Sara;Nemlaghi, Safaa;Bureau, Come;Mora, Pierre;De Sarcus, Martin;Clovet, Olivier;Duceau, Baptiste;Grisot, Paul Henri;Pari, Marie Helene;Arzoine, Jeremy;Clarac, Ulrich;Boutolleau, David;Raux, Mathieu;Delemazure, Ju...
10.1186/s13054-020-03117-9
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis. [Abstract]: BACKGROUND: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak is spreading worldwide. To date, no specif...