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32,401,218
JMIR Public Health Surveill
Emergency Response to COVID-19 in Canada: Platform Development and Implementation for eHealth in Crisis Management.
BACKGROUND: Public health emergencies like epidemics put enormous pressure on health care systems while revealing deep structural and functional problems in the organization of care. The current coronavirus disease (COVID-19) pandemic illustrates this at a global level. The sudden increased demand on delivery systems p...
covid-19;crisis management;digital health;ehealth;health care system;public health;web-based intervention
Journal Article
Krausz, Michael;Westenberg, Jean Nicolas;Vigo, Daniel;Spence, Richard Trafford;Ramsey, Damon
10.2196/18995
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency Response to COVID-19 in Canada: Platform Development and Implementation for eHealth in Crisis Management. [Abstract]: BACKGROUND: Public health emergencies like epidemics put enormous pressure on health care systems while revealing deep structural and functional problems in the organization of care. ...
32,692,241
Ann Palliat Med
Case analysis of novel coronavirus pneumonia in the Second Hospital of Wuhan Iron and Steel Company, Qingshan District, Wuhan, China.
BACKGROUND: To analyze the clinical and infectious characteristics of new coronavirus pneumonia with diagnosed and suspected cases in the Second Hospital of WISCO(Wuhan Iron and Steel Company) of Qingshan District, Wuhan City, and further enhance the understanding of new coronavirus pneumonia. METHODS: According to the...
new coronavirus pneumonia;clinical features;infectious diseases
Journal Article
Liu, Meirong;Lyu, Yang;Zhao, Wenchang;Yu, Shuang;Shi, Dongsheng;Lu, Wei
10.21037/apm-20-1372
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Case analysis of novel coronavirus pneumonia in the Second Hospital of Wuhan Iron and Steel Company, Qingshan District, Wuhan, China. [Abstract]: BACKGROUND: To analyze the clinical and infectious characteristics of new coronavirus pneumonia with diagnosed and suspected cases in the Second Hospital of WISCO(Wu...
32,997,373
J Med Virol
Changes in Computed Tomography Findings of COVID-19 Pneumonia: Less Extensive Lung Involvement with Decreasing Disease Prevalence.
OBJECTIVE: It has been observed that the degree of pulmonary involvement shown in chest computed tomography (CT) scans tended to decrease as the prevalence of coronavirus disease 2019 (COVID-19) infection decreased in the Turkish population. The purpose of this study was to investigate the relationship between the dise...
covid-19;coronavirus infections;pandemic curve;pneumonia
Journal Article
Gumus, Terman;Cengiz, Duygu;Kartal, Furkan;Atceken, Zeynep;Tekin, Suda;Atasoy, Kayhan Cetin
10.1002/jmv.26573
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Changes in Computed Tomography Findings of COVID-19 Pneumonia: Less Extensive Lung Involvement with Decreasing Disease Prevalence. [Abstract]: OBJECTIVE: It has been observed that the degree of pulmonary involvement shown in chest computed tomography (CT) scans tended to decrease as the prevalence of coronavir...
32,220,178
Sichuan Da Xue Xue Bao Yi Xue Ban
[Biological Product Development Strategies for Prevention and Treatment of Coronavirus Disease 2019].
Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has become a Public Health Emergency of International Concern. Due to the large infection population, broad transmissibility and high mortality, it is urgent to find out the e...
biological products;covid-19;mers;sars;sars-cov-2
Journal Article;Review
Yan, Cai-Xia;Li, Jia;Shen, Xin;Luo, Li;Li, Yan;Li, Ming-Yuan
10.12182/20200360506
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Biological Product Development Strategies for Prevention and Treatment of Coronavirus Disease 2019]. [Abstract]: Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has become a Public Health Emergency of Internationa...
32,425,267
Urology
Guess Who's Coming to Dinner: COVID-19 in a COVID-free Unit.
OBJECTIVE: To assess the impact of the pandemic on surgical activity and the occurrence and features of Covid-19 in a Covid-free urologic unit in a regional hospital in Northern Italy. MATERIALS AND METHODS: Our Department is the only urologic service in the Trento Province, near Lombardy, the epicenter of Covid-19 in ...
Comparative Study;Journal Article
Luciani, Lorenzo G;Mattevi, Daniele;Giusti, Guido;Proietti, Silvia;Gallo, Fabrizio;Schenone, Maurizio;Malossini, Gianni
10.1016/j.urology.2020.05.011
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Guess Who's Coming to Dinner: COVID-19 in a COVID-free Unit. [Abstract]: OBJECTIVE: To assess the impact of the pandemic on surgical activity and the occurrence and features of Covid-19 in a Covid-free urologic unit in a regional hospital in Northern Italy. MATERIALS AND METHODS: Our Department is the only uro...
33,061,927
Front Psychiatry
Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19.
Social isolation is likely to be recommended for older adults due to COVID-19, with ongoing reduced clinical contact suggested for this population. This has increased the need for remote memory clinics, we therefore review the literature, current practices and guidelines on organizing such remote memory clinics, focusi...
cognitive impairment;dementia;geriatric psychiatry and aging;neuropsychological assessment;remote measurement technologies;telemedicine
Journal Article
Owens, Andrew P;Ballard, Clive;Beigi, Mazda;Kalafatis, Chris;Brooker, Helen;Lavelle, Grace;Bronnick, Kolbjorn K;Sauer, Justin;Boddington, Steve;Velayudhan, Latha;Aarsland, Dag
10.3389/fpsyt.2020.579934
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19. [Abstract]: Social isolation is likely to be recommended for older adults due to COVID-19, with ongoing reduced clinical contact suggested for this population. This has increased the need for remote memory clinics, we theref...
32,678,072
MMWR Morb Mortal Wkly Rep
Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections - New York City, March 2020.
To limit introduction of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), the United States restricted travel from China on February 2, 2020, and from Europe on March 13. To determine whether local transmission of SARS-CoV-2 could be detected, the New York City (NYC) Department of Health and Menta...
Journal Article
Bushman, Dena;Alroy, Karen A;Greene, Sharon K;Keating, Page;Wahnich, Amanda;Weiss, Don;Pathela, Preeti;Harrison, Christy;Rakeman, Jennifer;Langley, Gayle;Tong, Suxiang;Tao, Ying;Uehara, Anna;Queen, Krista;Paden, Clinton R;Szymczak, Wendy;Orner, Erika P;Nori, Priya;Lai, Phi A;Jacobson, Jessica L;Singh, Harjot K;Calfee, ...
10.15585/mmwr.mm6928a5
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections - New York City, March 2020. [Abstract]: To limit introduction of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), the United States restricted travel from China on February 2, 2020, and from Europe on March 1...
32,249,471
Ultrasound Obstet Gynecol
Lung ultrasound and computed tomographic findings in pregnant woman with COVID-19.
Imaging modalities play a crucial role in the management of suspected COVID-19 patients. Before reverse transcription polymerase chain reaction (RT-PCR) test results are positive, 60-93% of patients have positive chest computed tomographic (CT) findings consistent with COVID-19. We report a case of positive lung ultras...
covid-19;sars-cov-2;consolidations;lung;pneumonia;pregnancy;tomography;ultrasound
Case Reports;Video-Audio Media
Kalafat, E;Yaprak, E;Cinar, G;Varli, B;Ozisik, S;Uzun, C;Azap, A;Koc, A
10.1002/uog.22034
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Lung ultrasound and computed tomographic findings in pregnant woman with COVID-19. [Abstract]: Imaging modalities play a crucial role in the management of suspected COVID-19 patients. Before reverse transcription polymerase chain reaction (RT-PCR) test results are positive, 60-93% of patients have positive che...
32,272,173
Antiviral Res
Coronavirus membrane fusion mechanism offers a potential target for antiviral development.
The coronavirus disease 2019 (COVID-19) pandemic has focused attention on the need to develop effective therapies against the causative agent, SARS-CoV-2, and also against other pathogenic coronaviruses (CoV) that have emerged in the past or might appear in future. Researchers are therefore focusing on steps in the CoV...
covid-19;fusion peptide;middle east respiratory syndrome;sars-cov-2;severe acute respiratory syndrome;spike protein
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Tang, Tiffany;Bidon, Miya;Jaimes, Javier A;Whittaker, Gary R;Daniel, Susan
10.1016/j.antiviral.2020.104792
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronavirus membrane fusion mechanism offers a potential target for antiviral development. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has focused attention on the need to develop effective therapies against the causative agent, SARS-CoV-2, and also against other pathogenic coronaviruses (CoV)...
32,863,947
Theranostics
Nanomedicine therapies modulating Macrophage Dysfunction: a potential strategy to attenuate Cytokine Storms in severe infections.
Cytokine storms, defined by the dysregulated and excessive production of multiple pro-inflammatory cytokines, are closely associated with the pathology and mortality of several infectious diseases, including coronavirus disease 2019 (COVID-19). Effective therapies are urgently needed to block the development of cytokin...
cytokine storm;macrophage dysfunction;nanomedicine;pro-inflammatory disease
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.;Review
Liu, Jingping;Wan, Meihua;Lyon, Christopher J;Hu, Tony Y
10.7150/thno.47982
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Nanomedicine therapies modulating Macrophage Dysfunction: a potential strategy to attenuate Cytokine Storms in severe infections. [Abstract]: Cytokine storms, defined by the dysregulated and excessive production of multiple pro-inflammatory cytokines, are closely associated with the pathology and mortality of ...
32,522,737
BMJ
Use of personal protective equipment against coronavirus disease 2019 by healthcare professionals in Wuhan, China: cross sectional study.
OBJECTIVE: To examine the protective effects of appropriate personal protective equipment for frontline healthcare professionals who provided care for patients with coronavirus disease 2019 (covid-19). DESIGN: Cross sectional study. SETTING: Four hospitals in Wuhan, China. PARTICIPANTS: 420 healthcare professionals (11...
Journal Article;Research Support, Non-U.S. Gov't
Liu, Min;Cheng, Shou-Zhen;Xu, Ke-Wei;Yang, Yang;Zhu, Qing-Tang;Zhang, Hui;Yang, Da-Ya;Cheng, Shu-Yuan;Xiao, Han;Wang, Ji-Wen;Yao, He-Rui;Cong, Yu-Tian;Zhou, Yu-Qi;Peng, Sui;Kuang, Ming;Hou, Fan-Fan;Cheng, K K;Xiao, Hai-Peng
10.1136/bmj.m2195
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Use of personal protective equipment against coronavirus disease 2019 by healthcare professionals in Wuhan, China: cross sectional study. [Abstract]: OBJECTIVE: To examine the protective effects of appropriate personal protective equipment for frontline healthcare professionals who provided care for patients w...
32,830,471
J Korean Med Sci
Proposal of the Autopsy Guideline for Infectious Diseases: Preparation for the Post-COVID-19 Era (abridged translation).
With the rapidly spreading coronavirus disease 2019 (COVID-19) pandemic over the past few months, the world is facing an unprecedented crisis. Innumerable lives have been lost to this novel infectious disease, the nature of which supersedes conventional medical understanding. The COVID-19 pandemic is not just a global ...
autopsy;covid-19;forensic medicine;guideline;infectious disease
Journal Article;Review
Kim, Moon Young;Cheong, Harin;Kim, Hyung Seok
10.3346/jkms.2020.35.e310
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Proposal of the Autopsy Guideline for Infectious Diseases: Preparation for the Post-COVID-19 Era (abridged translation). [Abstract]: With the rapidly spreading coronavirus disease 2019 (COVID-19) pandemic over the past few months, the world is facing an unprecedented crisis. Innumerable lives have been lost to...
32,666,025
Aging Med (Milton)
Expert consensus on the nursing management of critically ill elderly patients with coronavirus disease 2019.
The novel coronavirus (2019-nCoV) was first detected in patients with pneumonia of an unknown cause in Wuhan, China in December 2019. It has since been confirmed as the pathogen for the new coronavirus pneumonia, recently named "coronavirus disease 2019" (COVID-19) by the World Health Organization. Although the general...
critical illness;novel coronavirus;nursing;pneumonia
Journal Article
Wang, Xia;Sun, Chao;Hu, Hui-Xiu;Wang, Zi-Xin;Wang, Hui;Peng, Hua;Qiao, Jian-Hong;Gao, Lan
10.1002/agm2.12107
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Expert consensus on the nursing management of critically ill elderly patients with coronavirus disease 2019. [Abstract]: The novel coronavirus (2019-nCoV) was first detected in patients with pneumonia of an unknown cause in Wuhan, China in December 2019. It has since been confirmed as the pathogen for the new ...
32,437,918
Ann Vasc Surg
Ruptured Abdominal Aortic Aneurysm Treated with Endovascular Repair in a Patient with Active COVID-19 Infection during the Pandemic.
We report a patient who presented with acute abdominal pain during the COVID-19 pandemic. His work-up revealed rupture of a 5.8 cm abdominal aortic aneurysm. He also had fever, cough, and shortness of breath and radiologic evidence of COVID-19 infection. After careful consideration, he underwent successful endovascular...
Case Reports;Journal Article
Shih, Michael;Swearingen, Bruce;Rhee, Robert
10.1016/j.avsg.2020.05.001
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Ruptured Abdominal Aortic Aneurysm Treated with Endovascular Repair in a Patient with Active COVID-19 Infection during the Pandemic. [Abstract]: We report a patient who presented with acute abdominal pain during the COVID-19 pandemic. His work-up revealed rupture of a 5.8 cm abdominal aortic aneurysm. He also ...
32,387,409
Travel Med Infect Dis
Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France.
BACKGROUND: In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19. METHODS: We retrospectively report on 1061 SARS-CoV-2 positive tested patients treated for at least three days with the following regimen: HCQ (200 mg three times daily for ten days) + AZ (500 mg ...
azithromycin;covid-19;hydroxychloroquine;sars-cov-2
Journal Article
Million, Matthieu;Lagier, Jean-Christophe;Gautret, Philippe;Colson, Philippe;Fournier, Pierre-Edouard;Amrane, Sophie;Hocquart, Marie;Mailhe, Morgane;Esteves-Vieira, Vera;Doudier, Barbara;Aubry, Camille;Correard, Florian;Giraud-Gatineau, Audrey;Roussel, Yanis;Berenger, Cyril;Cassir, Nadim;Seng, Piseth;Zandotti, Christin...
10.1016/j.tmaid.2020.101738
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France. [Abstract]: BACKGROUND: In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19. METHODS: We retrospectively report ...
32,598,305
Clin Chem Lab Med
Do genetic polymorphisms in angiotensin converting enzyme 2 (ACE2) gene play a role in coronavirus disease 2019 (COVID-19)?
Although some demographic, clinical and environmental factors have been associated with a higher risk of developing coronavirus disease 2019 (COVID-19) and progressing towards severe disease, altogether these variables do not completely account for the different clinical presentations observed in patients with comparab...
covid-19;angiotensin;enzyme;polymorphism;receptor
Journal Article
Lippi, Giuseppe;Lavie, Carl J;Henry, Brandon M;Sanchis-Gomar, Fabian
10.1515/cclm-2020-0727
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Do genetic polymorphisms in angiotensin converting enzyme 2 (ACE2) gene play a role in coronavirus disease 2019 (COVID-19)? [Abstract]: Although some demographic, clinical and environmental factors have been associated with a higher risk of developing coronavirus disease 2019 (COVID-19) and progressing towards...
32,937,800
J Clin Med
Colchicine to Weather the Cytokine Storm in Hospitalized Patients with COVID-19.
The repurposing of colchicine for the treatment of COVID-19 was suggested based in its immunomodulatory, anti-inflammatory, and anti-viral properties. We performed a single-center propensity score matched cohort study, including all consecutive COVID-19 patients admitted to a community hospital between 1 March 2020 and...
covid-19;colchicine;coronavirus;cytokine storm;viral pneumonia
Journal Article
Brunetti, Luigi;Diawara, Oumou;Tsai, Andrew;Firestein, Bonnie L;Nahass, Ronald G;Poiani, George;Schlesinger, Naomi
10.3390/jcm9092961
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Colchicine to Weather the Cytokine Storm in Hospitalized Patients with COVID-19. [Abstract]: The repurposing of colchicine for the treatment of COVID-19 was suggested based in its immunomodulatory, anti-inflammatory, and anti-viral properties. We performed a single-center propensity score matched cohort study,...
32,322,102
Nat Med
Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy.
In Italy, 128,948 confirmed cases and 15,887 deaths of people who tested positive for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 pandemic requires implementation of multiple population-wide strategies, including social distancing, testing and contact tracing. We propose a new model that...
Journal Article;Research Support, Non-U.S. Gov't
Giordano, Giulia;Blanchini, Franco;Bruno, Raffaele;Colaneri, Patrizio;Di Filippo, Alessandro;Di Matteo, Angela;Colaneri, Marta
10.1038/s41591-020-0883-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy. [Abstract]: In Italy, 128,948 confirmed cases and 15,887 deaths of people who tested positive for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 pandemic requires implementation of multipl...
33,014,208
Inflamm Regen
How COVID-19 induces cytokine storm with high mortality.
The newly emerging coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, but has rapidly spread all over the world. Some COVID-19 patients encounter a severe symptom of acute respiratory distress syndrome (ARDS) with high mortality...
Journal Article;Review
Hojyo, Shintaro;Uchida, Mona;Tanaka, Kumiko;Hasebe, Rie;Tanaka, Yuki;Murakami, Masaaki;Hirano, Toshio
10.1186/s41232-020-00146-3
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: How COVID-19 induces cytokine storm with high mortality. [Abstract]: The newly emerging coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, but has rapidly spread all over the world. Some COVID-19 patients encounter a se...
32,746,653
Expert Rev Clin Pharmacol
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): recent progress and challenges.
INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and identify effective medication therapy strategies to combat the COVID-19. AREAS COVERED: Here, we summarized and evaluated the curr...
covid-19;coronavirus disease;sars-cov-2;medication therapy;therapeutic strategies
Journal Article;Review
Yang, Xiaolei;Liu, Ye;Liu, Yuping;Yang, Qing;Wu, Xubo;Huang, Xuan;Liu, Huijia;Cai, Weimin;Ma, Guo
10.1080/17512433.2020.1805315
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Medication therapy strategies for the coronavirus disease 2019 (COVID-19): recent progress and challenges. [Abstract]: INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and id...
32,932,574
Int J Mol Sci
Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections.
Lactoferrin is a naturally occurring iron-binding glycoprotein, produced and secreted by mucosal epithelial cells and neutrophils in various mammalian species, including humans. It is typically found in fluids like saliva, milk and tears, where it reaches the maximum concentration. Thanks to its unique anti-inflammator...
sars-cov-2;antimicrobial peptides;biofilm;dry eye;lactoferrin;ocular surface;viral infections
Journal Article;Review
Vagge, Aldo;Senni, Carlotta;Bernabei, Federico;Pellegrini, Marco;Scorcia, Vincenzo;Traverso, Carlo E;Giannaccare, Giuseppe
10.3390/ijms21186668
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections. [Abstract]: Lactoferrin is a naturally occurring iron-binding glycoprotein, produced and secreted by mucosal epithelial cells and neutrophils in various mammalian species, including humans. It is typically found in fluid...
32,912,964
Clin Med (Lond)
Coronavirus in the elderly: a late lockdown UK cohort.
OBJECTIVE: To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group. DESIGN: Retrospective observational cohort study of 115 patients at one acute district general hosp...
covid-19;sars-cov-2;elderly
Journal Article;Observational Study
Kerr, Andrew D;Stacpoole, Sybil Rl
10.7861/clinmed.2020-0423
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus in the elderly: a late lockdown UK cohort. [Abstract]: OBJECTIVE: To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group. DESIGN: Retrospective o...
32,661,499
Open Forum Infect Dis
Serum Iron Level as a Potential Predictor of Coronavirus Disease 2019 Severity and Mortality: A Retrospective Study.
Background: Various types of pulmonary diseases are associated with iron deficiency. However, information on iron status in coronavirus disease 2019 (COVID-19) is scarce. Methods: This study included 50 hospitalized patients with confirmed COVID-19. The role of serum iron in predicting severity and mortality of COVID-1...
coronavirus disease 2019;mortality;prediction;serum iron;severity
Journal Article
Zhao, Kang;Huang, Jucun;Dai, Dan;Feng, Yuwei;Liu, Liming;Nie, Shuke
10.1093/ofid/ofaa250
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Serum Iron Level as a Potential Predictor of Coronavirus Disease 2019 Severity and Mortality: A Retrospective Study. [Abstract]: Background: Various types of pulmonary diseases are associated with iron deficiency. However, information on iron status in coronavirus disease 2019 (COVID-19) is scarce. Methods: Th...
32,491,298
Pol Arch Intern Med
Sex differences in the frequency of gastrointestinal symptoms and olfactory or taste disorders in 1942 nonhospitalized patients with coronavirus disease 2019 (COVID-19).
INTRODUCTION: The coronavirus disease 2019 (COVID 19) is a communicable disease caused by a novel coronavirus. OBJECTIVES: This study aimed to assess selfreported frequency of gastrointestinal symptoms and olfactory or taste disorders in nonhospitalized patients with COVID19 in Poland. PATIENTS AND METHODS: This crosss...
Journal Article
Sierpinski, Radoslaw;Pinkas, Jaroslaw;Jankowski, Mateusz;Zgliczynski, Wojciech S;Wierzba, Waldemar;Gujski, Mariusz;Szumowski, Lukasz
10.20452/pamw.15414
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Sex differences in the frequency of gastrointestinal symptoms and olfactory or taste disorders in 1942 nonhospitalized patients with coronavirus disease 2019 (COVID-19). [Abstract]: INTRODUCTION: The coronavirus disease 2019 (COVID 19) is a communicable disease caused by a novel coronavirus. OBJECTIVES: This s...
32,537,957
J Korean Med Sci
Risk Factors for Mortality and Respiratory Support in Elderly Patients Hospitalized with COVID-19 in Korea.
BACKGROUND: The mortality risk of coronavirus disease 2019 (COVID-19) is higher in patients with older age, and many elderly patients are reported to require advanced respiratory support. METHODS: We reviewed medical records of 98 patients aged >/= 65 years who were hospitalized with COVID-19 during a regional outbreak...
covid-19;elderly;outcome;risk factors
Journal Article
Lee, Ji Yeon;Kim, Hyun Ah;Huh, Kyungmin;Hyun, Miri;Rhee, Ji Young;Jang, Sukbin;Kim, Ji Yeon;Peck, Kyong Ran;Chang, Hyun Ha
10.3346/jkms.2020.35.e223
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk Factors for Mortality and Respiratory Support in Elderly Patients Hospitalized with COVID-19 in Korea. [Abstract]: BACKGROUND: The mortality risk of coronavirus disease 2019 (COVID-19) is higher in patients with older age, and many elderly patients are reported to require advanced respiratory support. MET...
32,927,009
Genomics
Molecular phylogeny and missense mutations at envelope proteins across coronaviruses.
Envelope (E) protein is one of the structural viroporins (76-109 amino acids long) present in the coronavirus. Sixteen sequentially different E-proteins were observed from a total of 4917 available complete SARS-CoV-2 genomes as on 18th June 2020 in the NCBI database. The missense mutations over the envelope protein ac...
amino acid conservation;covid-19;envelope protein;phylogeny;sars-cov-2;viroporin
Journal Article
Hassan, Sk Sarif;Choudhury, Pabitra Pal;Roy, Bidyut
10.1016/j.ygeno.2020.09.014
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Molecular phylogeny and missense mutations at envelope proteins across coronaviruses. [Abstract]: Envelope (E) protein is one of the structural viroporins (76-109 amino acids long) present in the coronavirus. Sixteen sequentially different E-proteins were observed from a total of 4917 available complete SARS-C...
32,516,621
Public Health
Overview of rapid mitigating strategies in Singapore during the COVID-19 pandemic.
This article describes the rapid mitigation strategies in addressing the rising number of coronavirus disease 2019 (COVID-19) cases in Singapore. Learning from the severe acute respiratory syndrome experience in 2003, early preparation started in January 2020 when Wuhan was declared as the epicentre of the epidemic. Th...
covid-19;mitigating strategies;pandemic;rapid response
Journal Article;Review
Lee, W C;Ong, C Y
10.1016/j.puhe.2020.05.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Overview of rapid mitigating strategies in Singapore during the COVID-19 pandemic. [Abstract]: This article describes the rapid mitigation strategies in addressing the rising number of coronavirus disease 2019 (COVID-19) cases in Singapore. Learning from the severe acute respiratory syndrome experience in 2003...
32,904,541
SN Compr Clin Med
Age-Adjusted Risk Factors Associated with Mortality and Mechanical Ventilation Utilization Amongst COVID-19 Hospitalizations-a Systematic Review and Meta-Analysis.
The increasing COVID-19 cases in the USA have led to overburdening of healthcare in regard to invasive mechanical ventilation (IMV) utilization as well as mortality. We aim to identify risk factors associated with poor outcomes (IMV and mortality) of COVID-19 hospitalized patients. A meta-analysis of observational stud...
2019-ncov;covid risk factors;covid-19;covid-related complications;coronavirus disease;mechanical ventilation;mortality;sars-cov-2;severe acute respiratory syndrome
Journal Article
Patel, Urvish;Malik, Preeti;Usman, Muhammad Shariq;Mehta, Deep;Sharma, Ashish;Malik, Faizan Ahmad;Khan, Nashmia;Siddiqi, Tariq Jamal;Ahmed, Jawad;Patel, Achint;Sacks, Henry
10.1007/s42399-020-00476-w
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Age-Adjusted Risk Factors Associated with Mortality and Mechanical Ventilation Utilization Amongst COVID-19 Hospitalizations-a Systematic Review and Meta-Analysis. [Abstract]: The increasing COVID-19 cases in the USA have led to overburdening of healthcare in regard to invasive mechanical ventilation (IMV) uti...
32,472,706
J Med Virol
The long-standing history of Corynebacterium parvum, immunity, and viruses.
We report a review of all the experimental and clinical studies performed in the last 60 years on the antiviral activity of inactivated Corynebacterium parvum (Cutibacterium acnes). This bacterium has been originally investigated and used for its oncolytic properties linked to immunomodulating activity, but the interes...
c. parvum;coronavirus;immune responses;immunomodulation;innate immunity
Journal Article;Review
Palmieri, Beniamino;Vadala, Maria;Roncati, Luca;Garelli, Andrea;Scandone, Francesco;Bondi, Moreno;Cermelli, Claudio
10.1002/jmv.26100
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The long-standing history of Corynebacterium parvum, immunity, and viruses. [Abstract]: We report a review of all the experimental and clinical studies performed in the last 60 years on the antiviral activity of inactivated Corynebacterium parvum (Cutibacterium acnes). This bacterium has been originally invest...
32,692,733
Am J Case Rep
High-Dose Prednisone for Treatment of Autoimmune Pancreatitis in a Patient with Coronavirus Disease 2019 (COVID-19) due to Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
BACKGROUND Autoimmune pancreatitis (AIP) is a rare, steroid-responsive disease of the pancreas. Concurrent treatment with immunosuppressants, including corticosteroids, increases the risk of developing a severe form of coronavirus disease 2019 (COVID-19) due to infection with severe acute respiratory syndrome coronavir...
Case Reports;Journal Article
Liaquat, Hammad;Shupp, Brittney;Kapoor, Sarina;Matin, Ayaz
10.12659/AJCR.926475
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: High-Dose Prednisone for Treatment of Autoimmune Pancreatitis in a Patient with Coronavirus Disease 2019 (COVID-19) due to Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). [Abstract]: BACKGROUND Autoimmune pancreatitis (AIP) is a rare, steroid-responsive disease of the pancreas. Con...
32,492,995
Minerva Gastroenterol Dietol
COVID emergency: an opportunity to increase the interaction between hepatologist and primary care physician.
The outbreak of Coronavirus Disease 2019 (COVID-19) worldwide had evidenced the opportunity to increase the interaction between Specialist and Primary Care Physician (PCP). COVID 19, started in December 2019 in China, has been considered a public health emergency by the Department of Health and Human Services and, at t...
Journal Article;Review
Casella, Giovanni;Ingravalle, Fabio;Ingravalle, Adriana;Monti, Claudio;Bonetti, Fulvio;Limonta, Aurelio
10.23736/S1121-421X.20.02713-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID emergency: an opportunity to increase the interaction between hepatologist and primary care physician. [Abstract]: The outbreak of Coronavirus Disease 2019 (COVID-19) worldwide had evidenced the opportunity to increase the interaction between Specialist and Primary Care Physician (PCP). COVID 19, started...
32,923,256
Cureus
COVID-19 Presenting as Acute Abdominal Pain: A Case Report.
As the spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continues across the globe, more details about the disease manifestations and clinical course have been emerging. The main clinical presentation of the ongoing coronavirus disease-19 (COVID-19) pandemic is respiratory symptoms. Along with thi...
acute abdomen;acute pancreatitis;covid-19
Case Reports
Purayil, Nishan;Sirajudeen, Jaseem;Va, Naushad;Mathew, Joe
10.7759/cureus.9659
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 Presenting as Acute Abdominal Pain: A Case Report. [Abstract]: As the spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continues across the globe, more details about the disease manifestations and clinical course have been emerging. The main clinical presentation of the ongoing c...
32,675,154
Clin Med (Lond)
Lessons of the month 3: ST-elevation myocardial infarction and left ventricular thrombus formation: an arterial thrombotic complication of severe COVID-19 infection.
We describe a case of an 82-year-old man who developed an anterior ST-elevation myocardial infarction (STEMI) and left ventricular thrombus while an inpatient following a diagnosis of severe COVID-19 infection (SARS-CoV-2). His D-dimer was significantly elevated at 12,525 ng/mL (normal range <243). He unfortunately die...
covid-19;d-dimer;arterial thrombosis;myocardial infarction;ventricular thrombus
Case Reports;Journal Article
Fenton, Matthew;Siddavaram, Seshnag;Sugihara, Conn;Husain, Syed
10.7861/clinmed.2020-0266
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Lessons of the month 3: ST-elevation myocardial infarction and left ventricular thrombus formation: an arterial thrombotic complication of severe COVID-19 infection. [Abstract]: We describe a case of an 82-year-old man who developed an anterior ST-elevation myocardial infarction (STEMI) and left ventricular th...
32,470,161
Laryngoscope
Minimizing Contagion Risks of COVID-19 During Transoral Robotic Surgery.
In this communication, we would like to share our experience in managing TORS patients during COVID-19 pandemic. Laryngoscope, 130:2593-2594, 2020.
transoral robotic surgery;oropharyngeal;pandemic;tumour
Letter
Meccariello, Giuseppe;Cammaroto, Giovanni;Iannella, Giannicola;Capaccio, Pasquale;Pelucchi, Stefano;Vicini, Claudio
10.1002/lary.28847
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Minimizing Contagion Risks of COVID-19 During Transoral Robotic Surgery. [Abstract]: In this communication, we would like to share our experience in managing TORS patients during COVID-19 pandemic. Laryngoscope, 130:2593-2594, 2020. [Keywords]: transoral robotic surgery;oropharyngeal;pandemic;tumour
32,839,727
Curr Med Res Pract
Facial Trauma Management during the COVID-19 era: a primer for surgeons.
Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has caused more than 6.1 million confirmed cases of COVID-19 in more than 188 countries, and has caused more than 370,000 deaths globally as of June 1, 2020. In addition, thousands of healthcare workers have also ...
covid-19;emergency;omfs;sars-cov-2;trauma
Journal Article;Review
Ghai, Suhani
10.1016/j.cmrp.2020.07.011
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Facial Trauma Management during the COVID-19 era: a primer for surgeons. [Abstract]: Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has caused more than 6.1 million confirmed cases of COVID-19 in more than 188 countries, and has caused more than 370,0...
32,753,516
Clin Med (Lond)
Dying 'due to' or 'with' COVID-19: a cause of death analysis in hospitalised patients.
The SARS-CoV-2 pandemic is accompanied by an ever-rising death toll attributed to coronavirus disease 2019 (COVID-19), but questions have persisted regarding deaths formally attributed to COVID-19. We aimed to provide an independent review of clinical features of patients who died during hospitalisation with a positive...
covid-19;sars-cov-2;coronavirus
Journal Article
Slater, Thomas A;Straw, Sam;Drozd, Michael;Kamalathasan, Stephe;Cowley, Alice;Witte, Klaus K
10.7861/clinmed.2020-0440
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Dying 'due to' or 'with' COVID-19: a cause of death analysis in hospitalised patients. [Abstract]: The SARS-CoV-2 pandemic is accompanied by an ever-rising death toll attributed to coronavirus disease 2019 (COVID-19), but questions have persisted regarding deaths formally attributed to COVID-19. We aimed to pr...
32,350,226
Jpn J Infect Dis
Assessment of Real-Time RT-PCR Kits for SARS-CoV-2 Detection.
The coronavirus induced disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan (China) in December 2019 is currently spreading rapidly worldwide. We recently reported a laboratory protocol for the diagnosis of SARS-CoV-2 based on real-time reverse transcript...
covid-19;sars-cov-2;real-time rt-pcr
Comparative Study;Evaluation Study;Journal Article
Okamaoto, Kiyoko;Shirato, Kazuya;Nao, Naganori;Saito, Shinji;Kageyama, Tsutomu;Hasegawa, Hideki;Suzuki, Tadaki;Matsuyama, Shutoku;Takeda, Makoto
10.7883/yoken.JJID.2020.108
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Assessment of Real-Time RT-PCR Kits for SARS-CoV-2 Detection. [Abstract]: The coronavirus induced disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan (China) in December 2019 is currently spreading rapidly worldwide. We recently reported a labora...
33,011,516
Clin Neurol Neurosurg
Clinical characteristics and admission patterns of stroke patients during the COVID 19 pandemic: A single center retrospective, observational study from the Abu Dhabi, United Arab Emirates.
OBJECTIVE: To compare ischemic and hemorrhagic stroke patients with COVID-19 to non-COVID-19 controls, and to describe changes in stroke admission patterns during the pandemic. METHODS: This is a single center, retrospective, observational study. All consecutive patients admitted with primary diagnosis of ischemic/ hem...
admissions;covid-19;clinical characteristics;hemorrhagic;ischemic;stroke
Journal Article;Observational Study
John, Seby;Hussain, Syed Irteza;Piechowski-Jozwiak, Bartlomiej;Dibu, Jamil;Kesav, Praveen;Bayrlee, Ahmad;Elkambergy, Hussam;John, Terrence Lee St;Roser, Florian;Mifsud, Victoria Ann
10.1016/j.clineuro.2020.106227
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Clinical characteristics and admission patterns of stroke patients during the COVID 19 pandemic: A single center retrospective, observational study from the Abu Dhabi, United Arab Emirates. [Abstract]: OBJECTIVE: To compare ischemic and hemorrhagic stroke patients with COVID-19 to non-COVID-19 controls, and to...
32,894,641
Am J Transplant
Lung transplantation during the COVID-19 pandemic: Safely navigating the new "normal".
In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for manag...
Journal Article;Research Support, Non-U.S. Gov't
Halpern, Samantha E;Olaso, Danae G;Krischak, Madison K;Reynolds, John M;Haney, John C;Klapper, Jacob A;Hartwig, Matthew G
10.1111/ajt.16304
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Lung transplantation during the COVID-19 pandemic: Safely navigating the new "normal". [Abstract]: In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a ...
32,893,468
Environ Microbiol
Efforts towards a COVID-19 vaccine.
To many scientists and political authorities, the development of a vaccine against Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be the way to restore normality to civil life in this time of a devastating pandemic. Expectations for a vaccine are high while the case numbers continue to rise. As of mi...
Journal Article;Review
Brussow, Harald
10.1111/1462-2920.15225
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efforts towards a COVID-19 vaccine. [Abstract]: To many scientists and political authorities, the development of a vaccine against Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be the way to restore normality to civil life in this time of a devastating pandemic. Expectations for a vaccine a...
32,834,417
Build Environ
Impact of intervention methods on COVID-19 transmission in Shenzhen.
By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases were reported, leading to more than 36,000 deaths. In this study, we analysed the efficiency of various intervention strategies to prevent infection by the virus, SARS-CoV-2, using an agent-based SEIIR model, in the fully ur...
agent-based model;covid-19;close contact;infection spread;seir model
Journal Article
Zhang, Nan;Cheng, Pan;Jia, Wei;Dung, Chung-Hin;Liu, Li;Chen, Wenzhao;Lei, Hao;Kan, Changcheng;Han, Xiaoyan;Su, Boni;Xiao, Shenglan;Qian, Hua;Lin, Borong;Li, Yuguo
10.1016/j.buildenv.2020.107106
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Impact of intervention methods on COVID-19 transmission in Shenzhen. [Abstract]: By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases were reported, leading to more than 36,000 deaths. In this study, we analysed the efficiency of various intervention strategies to pre...
32,370,981
Encephale
[Evolution of electro-convulsive therapy activity in France since the beginning of the COVID-19 pandemic].
The recent COVID-19 pandemic has led to major organisational changes in health care settings, especially in psychiatric hospitals. We conducted a national online survey to assess the evolution of electroconvulsive therapy (ECT) in the different centres practicing this treatment. 65 responses from all over France were a...
acces aux soins;covid-19;complications;electroconvulsive therapy;epidemiology;health care access;pandemie;electro-convulsivo-therapie;epidemiologie
Journal Article
Amad, A;Magnat, M;Quiles, C;Yrondi, A;Sauvaget, A;Bulteau, S;Plaze, M;Rotharmel, M;Polosan, M;Levy-Chavagnat, D;Jaafari, N;Vaiva, G;Thomas, P
10.1016/j.encep.2020.04.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Evolution of electro-convulsive therapy activity in France since the beginning of the COVID-19 pandemic]. [Abstract]: The recent COVID-19 pandemic has led to major organisational changes in health care settings, especially in psychiatric hospitals. We conducted a national online survey to assess the evolution...
32,472,655
Phytother Res
Cytokine storm in COVID-19 and parthenolide: Preclinical evidence.
A group of patients with pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were reported from China in December 2019. Although several antiviral drugs are widely tested, none of them has been approved as specific antiviral therapy for coronavirus disease 2019 (COVID-19). Accumulating evid...
tanacetum parthenium;covid-19;coronavirus;feverfew;parthenolide
Letter
Bahrami, Mohsen;Kamalinejad, Mohammad;Latifi, Seied Amirhossein;Seif, Farhad;Dadmehr, Majid
10.1002/ptr.6776
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Cytokine storm in COVID-19 and parthenolide: Preclinical evidence. [Abstract]: A group of patients with pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were reported from China in December 2019. Although several antiviral drugs are widely tested, none of them has been approved ...
33,041,473
Math Comput Simul
COVID-19 pandemic and chaos theory.
The dynamics of COVID-19 is investigated with regard to complex contributions of the omitted factors. For this purpose, we use a fractional order SEIR model which allows us to calculate the number of infections considering the chaotic contributions into susceptible, exposed, infectious and removed number of individuals...
bernoulli polynomials;block-pulse;caputo derivative;epidemic models
Journal Article
Postavaru, O;Anton, S R;Toma, A
10.1016/j.matcom.2020.09.029
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: COVID-19 pandemic and chaos theory. [Abstract]: The dynamics of COVID-19 is investigated with regard to complex contributions of the omitted factors. For this purpose, we use a fractional order SEIR model which allows us to calculate the number of infections considering the chaotic contributions into susceptib...
32,934,757
Inflamm Regen
Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders.
It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS) disorders. However, little is known about the mechanism that triggers the COVID-19-associated CNS disorders, due to the lack of appropriate experimental systems....
ace2;ccn1 (cyr61);cns disorder;covid-19;sars-cov-2;hipsc-ns/pcs
Journal Article
Kase, Yoshitaka;Okano, Hideyuki
10.1186/s41232-020-00143-6
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders. [Abstract]: It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including centr...
32,834,589
Chaos Solitons Fractals
Influence of isolation measures for patients with mild symptoms on the spread of COVID-19.
During the transmission of COVID-19, the hospital isolation of patients with mild symptoms has been a concern. In this paper, we use a differential equation model to describe the propagation of COVID-19, and discuss the effects of intensity of hospital isolation and moment of taking measures on development of the epide...
covid-19;differential equation model;isolation measure;patients with mild symptoms;the reproduction number
Journal Article
Pan, Qiuhui;Gao, Ting;He, Mingfeng
10.1016/j.chaos.2020.110022
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Influence of isolation measures for patients with mild symptoms on the spread of COVID-19. [Abstract]: During the transmission of COVID-19, the hospital isolation of patients with mild symptoms has been a concern. In this paper, we use a differential equation model to describe the propagation of COVID-19, and ...
33,032,618
Global Health
Equity and elderly health in India: reflections from 75th round National Sample Survey, 2017-18, amidst the COVID-19 pandemic.
BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) outbreak, called coronavirus disease - 2019 (COVID-19), has affected more than 200 countries across the globe with a higher fatality rate among the elderly population. Aim of the study is to highlight the vulnerability of the aged amidst the curre...
covid-19;elderly heath;equity;india
Journal Article
Ranjan, Alok;Muraleedharan, V R
10.1186/s12992-020-00619-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Equity and elderly health in India: reflections from 75th round National Sample Survey, 2017-18, amidst the COVID-19 pandemic. [Abstract]: BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) outbreak, called coronavirus disease - 2019 (COVID-19), has affected more than 200 countries across...
32,864,070
J Ophthalmic Vis Res
Ophthalmic Workplace Modifications for the Post-COVID Era.
The COVID-19 pandemic necessitates implementation of exposure control measures in all facets of the healthcare sector. Healthcare professionals who work in busy ophthalmology clinics and theaters are amidst the highest at-risk of contracting COVID-19. The authors review the up-to-date scientific evidence of SARS-CoV-2 ...
ophthalmic workplace;personal protective equipment;protecting healthcare workers;sars-cov-2;covid-19
Journal Article;Review
Naveed, Hasan;Leung, Victor;Zarei-Ghanavati, Mehran;Leak, Christopher;Liu, Christopher
10.18502/jovr.v15i3.7458
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Ophthalmic Workplace Modifications for the Post-COVID Era. [Abstract]: The COVID-19 pandemic necessitates implementation of exposure control measures in all facets of the healthcare sector. Healthcare professionals who work in busy ophthalmology clinics and theaters are amidst the highest at-risk of contractin...
32,556,438
Knee Surg Sports Traumatol Arthrosc
The negative impact of the COVID-19 lockdown on pain and physical function in patients with end-stage hip or knee osteoarthritis.
PURPOSE: The purpose of this study was to evaluate pain, functional impairment, mental health, and daily activity in patients with end-stage hip and knee osteoarthritis (OA) during the COVID-19 lockdown. METHODS: The study included 63 patients, with hip or knee OA, who had been scheduled for arthroplasty that was postp...
arthroplasty;covid-19;mental health;osteoarthritis, hip;osteoarthritis, knee;physical functional performance
Journal Article
Endstrasser, Franz;Braito, Matthias;Linser, Markus;Spicher, Anna;Wagner, Moritz;Brunner, Alexander
10.1007/s00167-020-06104-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The negative impact of the COVID-19 lockdown on pain and physical function in patients with end-stage hip or knee osteoarthritis. [Abstract]: PURPOSE: The purpose of this study was to evaluate pain, functional impairment, mental health, and daily activity in patients with end-stage hip and knee osteoarthritis ...
32,401,466
Drugs and Lactation Database (LactMed)
Remdesivir
No information is available on the use of remdesivir during breastfeeding. Remdesivir is given intravenously because it is poorly absorbed orally, so infants are not likely to absorb clinically important amounts of the drug from milk. In addition, a newborn infants have received intravenous remdesivir therapy for Ebola...
remdesevir;veklury;gs-573;gs-5734;2-ethylbutyl (2s)-2-(((s)-(((2r,3s,4r,5r)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano -3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;l-alanine, n-((s)-hydroxyphenoxyphosphinyl)-, 2-ethylbutyl ester, 6-ester with 2-c-(4-aminopyrrolo(2,1-f)(1,2,4...
Review;Book Chapter
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Remdesivir [Abstract]: No information is available on the use of remdesivir during breastfeeding. Remdesivir is given intravenously because it is poorly absorbed orally, so infants are not likely to absorb clinically important amounts of the drug from milk. In addition, a newborn infants have received intraven...
32,490,846
JMIR Public Health Surveill
Machine Learning to Detect Self-Reporting of Symptoms, Testing Access, and Recovery Associated With COVID-19 on Twitter: Retrospective Big Data Infoveillance Study.
BACKGROUND: The coronavirus disease (COVID-19) pandemic is a global health emergency with over 6 million cases worldwide as of the beginning of June 2020. The pandemic is historic in scope and precedent given its emergence in an increasingly digital era. Importantly, there have been concerns about the accuracy of COVID...
covid-19;twitter;infoveillance;machine learning;surveillance
Journal Article
Mackey, Tim;Purushothaman, Vidya;Li, Jiawei;Shah, Neal;Nali, Matthew;Bardier, Cortni;Liang, Bryan;Cai, Mingxiang;Cuomo, Raphael
10.2196/19509
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Machine Learning to Detect Self-Reporting of Symptoms, Testing Access, and Recovery Associated With COVID-19 on Twitter: Retrospective Big Data Infoveillance Study. [Abstract]: BACKGROUND: The coronavirus disease (COVID-19) pandemic is a global health emergency with over 6 million cases worldwide as of the beg...
32,982,151
Clin Ophthalmol
Impact of the COVID-19 Pandemic on Essential Vitreoretinal Care with Three Epicenters in the United States.
Purpose: To report the impact of COVID-19 on retina practices in three different "hot spot" cities in the United States. Patients and Methods: The authors assessed data of encounters and intravitreal injections from March 16th to May 8th 2020, at different offices specializing in retina in the United States. All three ...
covid-19;medical practice;ophthalmology;pandemic;retina
Journal Article
El Hamichi, Sophia;Gold, Aaron;Heier, Jeffrey;Kiss, Szilard;Murray, Timothy G
10.2147/OPTH.S267950
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of the COVID-19 Pandemic on Essential Vitreoretinal Care with Three Epicenters in the United States. [Abstract]: Purpose: To report the impact of COVID-19 on retina practices in three different "hot spot" cities in the United States. Patients and Methods: The authors assessed data of encounters and intr...
32,802,338
Ann Occup Environ Med
Fighting the COVID-19 pandemic: onsite mass workplace testing for COVID-19 in the Republic of Korea.
The ongoing coronavirus disease 2019 (COVID-19) pandemic is causing tremendous damage globally. The Republic of Korea (ROK), a highly export-dependent nation, is a leader in the fight against the COVID-19 pandemic and coping well with the disaster. Like the drive-through COVID-19 testing, which reflects the brilliant f...
covid-19;mass testing;physical examination;workplace
Journal Article
Seo, Eunhye;Mun, Eunchan;Kim, Wonsool;Lee, Changhwan
10.35371/aoem.2020.32.e22
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Fighting the COVID-19 pandemic: onsite mass workplace testing for COVID-19 in the Republic of Korea. [Abstract]: The ongoing coronavirus disease 2019 (COVID-19) pandemic is causing tremendous damage globally. The Republic of Korea (ROK), a highly export-dependent nation, is a leader in the fight against the CO...
32,789,730
J Thromb Thrombolysis
In vivo demonstration of microvascular thrombosis in severe COVID-19.
Several autopsy studies showed microthrombi in pulmonary circulation of severe COVID-19 patients. The major limitation of these investigations is that the autopsy provided static information. Some of these alterations could be secondary to the disseminated intravascular coagulation (DIC) observed as the final standard ...
covid-19;coagulopathy;microvascular thrombosis;sublingual microcirculation
Journal Article
do Espirito Santo, Douglas Alexandre;Lemos, Anna Cristina Bertoldi;Miranda, Carlos Henrique
10.1007/s11239-020-02245-x
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: In vivo demonstration of microvascular thrombosis in severe COVID-19. [Abstract]: Several autopsy studies showed microthrombi in pulmonary circulation of severe COVID-19 patients. The major limitation of these investigations is that the autopsy provided static information. Some of these alterations could be se...
32,881,661
Comb Chem High Throughput Screen
Discovery of Some Antiviral Natural products to fight against Novel Corona Virus (SARS-CoV-2) using Insilico approach.
BACKGROUND: Novel Corona virus is a type of enveloped viruses with a single stranded RNA enclosing helical nucleocapsid. The envelope consists of spikes on the surface which are made up of proteins through which virus enters into human cells. Until now there is no specific drug or vaccine available to treat COVID-19 in...
covid-19;covid-19 main protease (3cl pro);insilico screening;papain-like protease (pl pro);phytoconstituents;spike protein (s) attached to ace2 binding domain
Journal Article
Shah, Ashish;Patel, Vaishali;Parmar, Bhumika
10.2174/1386207323666200902135928
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Discovery of Some Antiviral Natural products to fight against Novel Corona Virus (SARS-CoV-2) using Insilico approach. [Abstract]: BACKGROUND: Novel Corona virus is a type of enveloped viruses with a single stranded RNA enclosing helical nucleocapsid. The envelope consists of spikes on the surface which are ma...
32,879,096
Zhong Nan Da Xue Xue Bao Yi Xue Ban
Emergency management for kidney transplantation in the epidemic period of coronavirus disease 2019.
OBJECTIVES: To summarize the emergency management of the kidney transplantation for a large tertiary first-class hospital in response to the epidemic of coronavirus disease 2019 (COVID-19). METHODS: The clinical data of inpatients in the Department of Kidney Transplantation from January 24, 2020 to February 29, 2020 we...
coronavirus disease 2019;kidney transplantation;management;pneumonia
Journal Article
Fang, Chunhua;Wang, Liping;Nie, Manhua;Liu, Yajie;Huang, Jin;Xie, Xubiao
10.11817/j.issn.1672-7347.2020.200196
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency management for kidney transplantation in the epidemic period of coronavirus disease 2019. [Abstract]: OBJECTIVES: To summarize the emergency management of the kidney transplantation for a large tertiary first-class hospital in response to the epidemic of coronavirus disease 2019 (COVID-19). METHODS: ...
32,689,650
J Stroke Cerebrovasc Dis
Collateral damage - Impact of a pandemic on stroke emergency services.
BACKGROUND: The COVID-19 pandemic's impact on stroke care is two-fold direct impact of the infection and indirect impact on non-COVID-19 diseases. Anecdotal evidence and clinical observation suggest that there is a decrease in the number of patients presenting with stroke during the pandemic. We aim to understand the i...
covid;epidemiology;stroke;tia;thrombectomy
Comparative Study;Journal Article
Desai, Shashvat M;Guyette, Francis X;Martin-Gill, Christian;Jadhav, Ashutosh P
10.1016/j.jstrokecerebrovasdis.2020.104988
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Collateral damage - Impact of a pandemic on stroke emergency services. [Abstract]: BACKGROUND: The COVID-19 pandemic's impact on stroke care is two-fold direct impact of the infection and indirect impact on non-COVID-19 diseases. Anecdotal evidence and clinical observation suggest that there is a decrease in t...
32,622,796
J Infect Public Health
Prevalence and predictive value of hypocalcemia in severe COVID-19 patients.
BACKGROUND: The aim of this study was to investigate the performance and predictive value of hypocalcemia in severe COVID-19 patients. METHODS: We retrospectively investigated the clinical and laboratory characteristics of severe COVID-19 patients. 107 patients were divided into hypocalcemia group and normal serum calc...
covid-19;clinical characteristics;hypocalcemia;prognosis
Journal Article
Liu, Jingmei;Han, Ping;Wu, Jingwen;Gong, Jin;Tian, Dean
10.1016/j.jiph.2020.05.029
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prevalence and predictive value of hypocalcemia in severe COVID-19 patients. [Abstract]: BACKGROUND: The aim of this study was to investigate the performance and predictive value of hypocalcemia in severe COVID-19 patients. METHODS: We retrospectively investigated the clinical and laboratory characteristics of...
32,798,094
Semin Perinatol
Outcomes and epidemiology of COVID-19 infection in the obstetric population.
As of June 19, 2020 there are more than 8.6 million COVID-19 cases worldwide with over 450,000 deaths. Providing obstetrical care in the setting of the pandemic poses challenges to the healthcare system in that, in comparison to many other medical specialties, obstetrical care cannot be deferred. Pregnant patients repr...
Journal Article;Review
Sutton, Desmond;Bertozzi-Villa, Clara;Lasky, James;Fuchs, Karin;Friedman, Alexander
10.1016/j.semperi.2020.151283
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: Outcomes and epidemiology of COVID-19 infection in the obstetric population. [Abstract]: As of June 19, 2020 there are more than 8.6 million COVID-19 cases worldwide with over 450,000 deaths. Providing obstetrical care in the setting of the pandemic poses challenges to the healthcare system in that, in compari...
32,995,681
Infect Dis Model
Bayesian modeling of COVID-19 cases with a correction to account for under-reported cases.
The novel of COVID-19 disease started in late 2019 making the worldwide governments came across a high number of critical and death cases, beyond constant fear of the collapse in their health systems. Since the beginning of the pandemic, researchers and authorities are mainly concerned with carrying out quantitative st...
bayesian aproach;covid-19;sir model;under-reporting
Journal Article
de Oliveira, Anderson Castro Soares;Morita, Lia Hanna Martins;da Silva, Eveliny Barroso;Zardo, Luiz Andre Ribeiro;Fontes, Cor Jesus Fernandes;Granzotto, Daniele Cristina Tita
10.1016/j.idm.2020.09.005
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Bayesian modeling of COVID-19 cases with a correction to account for under-reported cases. [Abstract]: The novel of COVID-19 disease started in late 2019 making the worldwide governments came across a high number of critical and death cases, beyond constant fear of the collapse in their health systems. Since t...
33,042,659
Cureus
Coronavirus Disease 2019-Associated Bilateral Massive Pulmonary Emboli Caused Death in a Healthy 35-Year-Old Patient.
Coronavirus disease 2019 (COVID-19) infection was first reported in December 2019. Within three months, the virus caused a global pandemic that has affected the whole world's dynamics. Many causes of death due to COVID-19 infection have been identified, involving but not limited to atypical acute respiratory distress s...
coronavirus disease (covid-19);covid-19 infection;massive pulmonary embolism
Case Reports
Al Sbihi, Ali F;Manasrah, Nouraldeen;Kosti, Jorgena;Alhassan, Sulaiman
10.7759/cureus.10213
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Coronavirus Disease 2019-Associated Bilateral Massive Pulmonary Emboli Caused Death in a Healthy 35-Year-Old Patient. [Abstract]: Coronavirus disease 2019 (COVID-19) infection was first reported in December 2019. Within three months, the virus caused a global pandemic that has affected the whole world's dynami...
32,802,983
Heliyon
Study of the structural, chemical descriptors and optoelectronic properties of the drugs Hydroxychloroquine and Azithromycin.
Density functional theory (DFT) was performed in order to predict the structural, chemical descriptors and optoelectronic properties of the drugs Hydroxychloroquine and Azithromycin using the wB97XD, O3LYP and B3LYP functional with 6-31+G(d,p) basis set. It is observed from our studies that most of the descriptors pres...
azithromycin;covid-19;chemical descriptors;hydroxychloroquine;nonlinear optical application;optoelectronic devices;pharmaceutical chemistry
Journal Article;Review
Ejuh, G W;Fonkem, C;Tadjouteu Assatse, Y;Yossa Kamsi, R A;Nya, Tchangnwa;Ndukum, L P;Ndjaka, J M B
10.1016/j.heliyon.2020.e04647
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Study of the structural, chemical descriptors and optoelectronic properties of the drugs Hydroxychloroquine and Azithromycin. [Abstract]: Density functional theory (DFT) was performed in order to predict the structural, chemical descriptors and optoelectronic properties of the drugs Hydroxychloroquine and Azit...
33,050,737
Am J Physiol Lung Cell Mol Physiol
Hyperoxia and modulation of pulmonary vascular and immune responses in COVID-19.
Oxygen is the most commonly used therapy in hospitalized patients with COVID-19. In those patients who develop worsening pneumonia and acute respiratory distress syndrome (ARDS), high concentrations of oxygen may need to be administered for prolonged time periods, often together with mechanical ventilation. Hyperoxia, ...
covid-19;hyperoxia;lung injury;microcirculation
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Hanidziar, Dusan;Robson, Simon C
10.1152/ajplung.00304.2020
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Hyperoxia and modulation of pulmonary vascular and immune responses in COVID-19. [Abstract]: Oxygen is the most commonly used therapy in hospitalized patients with COVID-19. In those patients who develop worsening pneumonia and acute respiratory distress syndrome (ARDS), high concentrations of oxygen may need ...
32,788,319
Respir Care
Intubation Checklist for COVID-19 Patients: A Practical Tool for Bedside Practitioners.
BACKGROUND: The high frequency of aerosolizing procedures in the ICU, including endotracheal intubation, places clinical staff at elevated risk of contracting the 2019 coronavirus (COVID-19). Use of an intubation checklist can reduce exposure risk and thus acts as a potential safeguard. Specific, step-by-step guidance ...
covid;icu;checklist;intubation;pandemic;protocol;quality improvement;safety
Journal Article
Papali, Alfred;Ingram, Anna O;Rosenberger, Amy M;D'Arcy, Frances R;Singh, Jaspal;Ahlberg, Lisa;Russell, Christopher D
10.4187/respcare.08063
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Intubation Checklist for COVID-19 Patients: A Practical Tool for Bedside Practitioners. [Abstract]: BACKGROUND: The high frequency of aerosolizing procedures in the ICU, including endotracheal intubation, places clinical staff at elevated risk of contracting the 2019 coronavirus (COVID-19). Use of an intubatio...
32,796,842
Nat Commun
A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge.
The unprecedented coronavirus disease 2019 (COVID-19) epidemic has created a worldwide public health emergency, and there is an urgent need to develop an effective vaccine to control this severe infectious disease. Here, we find that a single vaccination with a replication-defective human type 5 adenovirus encoding the...
Journal Article;Research Support, Non-U.S. Gov't
Wu, Shipo;Zhong, Gongxun;Zhang, Jun;Shuai, Lei;Zhang, Zhe;Wen, Zhiyuan;Wang, Busen;Zhao, Zhenghao;Song, Xiaohong;Chen, Yi;Liu, Renqiang;Fu, Ling;Zhang, Jinlong;Guo, Qiang;Wang, Chong;Yang, Yilong;Fang, Ting;Lv, Peng;Wang, Jinliang;Xu, Junjie;Li, Jianmin;Yu, Changming;Hou, Lihua;Bu, Zhigao;Chen, Wei
10.1038/s41467-020-17972-1
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge. [Abstract]: The unprecedented coronavirus disease 2019 (COVID-19) epidemic has created a worldwide public health emergency, and there is an urgent need to develop an effective vaccine to control this severe infect...
32,750,013
J Med Internet Res
Grappling With the COVID-19 Health Crisis: Content Analysis of Communication Strategies and Their Effects on Public Engagement on Social Media.
BACKGROUND: The coronavirus disease (COVID-19) has posed an unprecedented challenge to governments worldwide. Effective government communication of COVID-19 information with the public is of crucial importance. OBJECTIVE: We investigate how the most-read state-owned newspaper in China, People's Daily, used an online so...
covid-19;communication;content analysis;framework;health content frames;infodemic;infodemiology;interactive features;message style;public engagement;social media
Journal Article
Ngai, Cindy Sing Bik;Singh, Rita Gill;Lu, Wenze;Koon, Alex Chun
10.2196/21360
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Grappling With the COVID-19 Health Crisis: Content Analysis of Communication Strategies and Their Effects on Public Engagement on Social Media. [Abstract]: BACKGROUND: The coronavirus disease (COVID-19) has posed an unprecedented challenge to governments worldwide. Effective government communication of COVID-1...
32,898,920
Am J Perinatol
Breastfeeding in COVID-19: A Pragmatic Approach.
The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in changes to perinatal and neonatal care, concentrating on minimizing risks of transmission to the newborn and health care staff while ensuring medical care is not compromised for both mother and infant. Current recommendations on infant care and feed...
Journal Article
Ng, Yvonne Peng Mei;Low, Yi Fen;Goh, Xin Lei;Fok, Doris;Amin, Zubair
10.1055/s-0040-1716506
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Breastfeeding in COVID-19: A Pragmatic Approach. [Abstract]: The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in changes to perinatal and neonatal care, concentrating on minimizing risks of transmission to the newborn and health care staff while ensuring medical care is not compromised for b...
32,921,197
Leuk Lymphoma
Diagnosing lymphoma in the shadow of an epidemic: lessons learned from the diagnostic challenges posed by the dual tuberculosis and HIV epidemics.
Infectious disease epidemics may overshadow and exacerbate existing challenges in diagnosing lymphoma. We describe pragmatic strategies we have implemented to overcome diagnostic obstacles caused by the local tuberculosis (TB) and HIV epidemics in South Africa, which may serve as a guide to minimize diagnostic delay du...
covid-19;hiv;lymphoma;diagnosis;tuberculosis
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Antel, Katherine;Louw, Vernon Johan;Maartens, Gary;Oosthuizen, Jenna;Verburgh, Estelle
10.1080/10428194.2020.1815016
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnosing lymphoma in the shadow of an epidemic: lessons learned from the diagnostic challenges posed by the dual tuberculosis and HIV epidemics. [Abstract]: Infectious disease epidemics may overshadow and exacerbate existing challenges in diagnosing lymphoma. We describe pragmatic strategies we have implemen...
32,896,785
Int J Hyg Environ Health
Impacts of transportation and meteorological factors on the transmission of COVID-19.
The ongoing pandemic of 2019 novel coronavirus disease (COVID-19) is challenging global public health response system. We aim to identify the risk factors for the transmission of COVID-19 using data on mainland China. We estimated attack rate (AR) at county level. Logistic regression was used to explore the role of tra...
covid-19;china;interaction;meteorological factors;transportation
Journal Article
Wei, Jia-Te;Liu, Yun-Xia;Zhu, Yu-Chen;Qian, Jie;Ye, Run-Ze;Li, Chun-Yu;Ji, Xiao-Kang;Li, Hong-Kai;Qi, Chang;Wang, Ying;Yang, Fan;Zhou, Yu-Hao;Yan, Ran;Cui, Xiao-Ming;Liu, Yuan-Li;Jia, Na;Li, Shi-Xue;Li, Xiu-Jun;Xue, Fu-Zhong;Zhao, Lin;Cao, Wu-Chun
10.1016/j.ijheh.2020.113610
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Impacts of transportation and meteorological factors on the transmission of COVID-19. [Abstract]: The ongoing pandemic of 2019 novel coronavirus disease (COVID-19) is challenging global public health response system. We aim to identify the risk factors for the transmission of COVID-19 using data on mainland Ch...
33,069,200
Rev Recent Clin Trials
Erythema Pernio-like in four Adolescents in the era of the Coronavirus-2 Infection.
BACKGROUND: Although epidemic, novel coronavirus (SARS-CoV-2) infection rarely affects pediatric population. However, in the last months an increasing number of Italian pediatricians has reported the occurrence of erythema pernio-like in children following a flu-like syndrome, after the outbreak of SARS-CoV-2 infection...
covid-19;chilblain-like lesion;sars-cov-2;children;coronavirus;erythema pernio-like;pediatric population.
Case Reports
Promenzio, Luigi;Arcangeli, Fabio;Cortis, Elisabetta;Sama, Elisa;Longhini, Federico
10.2174/1574887115666201016153031
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Erythema Pernio-like in four Adolescents in the era of the Coronavirus-2 Infection. [Abstract]: BACKGROUND: Although epidemic, novel coronavirus (SARS-CoV-2) infection rarely affects pediatric population. However, in the last months an increasing number of Italian pediatricians has reported the occurrence of e...
32,699,006
CMAJ
For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths.
BACKGROUND: Long-term care (LTC) homes have been the epicentre of the coronavirus disease 2019 (COVID-19) pandemic in Canada to date. Previous research shows that for-profit LTC homes deliver inferior care across a variety of outcome and process measures, raising the question of whether for-profit homes have had worse ...
Journal Article
Stall, Nathan M;Jones, Aaron;Brown, Kevin A;Rochon, Paula A;Costa, Andrew P
10.1503/cmaj.201197
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths. [Abstract]: BACKGROUND: Long-term care (LTC) homes have been the epicentre of the coronavirus disease 2019 (COVID-19) pandemic in Canada to date. Previous research shows that for-profit LTC homes deliver inferior care acros...
32,585,464
Med Hypotheses
WHO statement - "Older people are at highest risk from COVID-19": Should the hypothesis be corroborated or rejected?
Coronavirus COVID 19 has become a threat to mankind affecting millions of people worldwide. United States, Italy and Spain has the highest number of Coronavirus cases as of April 30, 2020. According to World Health Organization (WHO) statement - "Older people are at highest risk from COVID-19". However, in contrast to ...
covid-19;corona;who
Letter
Ningthoujam, Ramananda;Khomdram, Deepa
10.1016/j.mehy.2020.109896
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: WHO statement - "Older people are at highest risk from COVID-19": Should the hypothesis be corroborated or rejected? [Abstract]: Coronavirus COVID 19 has become a threat to mankind affecting millions of people worldwide. United States, Italy and Spain has the highest number of Coronavirus cases as of April 30,...
32,065,057
Emerg Microbes Infect
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes.
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tract and then induced pneumonia, thus molecular diagnosis based on oral swabs was used for confirmation of this disease. ...
2019-ncov;wuhan pneumonia;epidemiology;intestine;swabs
Journal Article
Zhang, Wei;Du, Rong-Hui;Li, Bei;Zheng, Xiao-Shuang;Yang, Xing-Lou;Hu, Ben;Wang, Yan-Yi;Xiao, Geng-Fu;Yan, Bing;Shi, Zheng-Li;Zhou, Peng
10.1080/22221751.2020.1729071
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. [Abstract]: In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through ...
33,052,154
Trends Analyt Chem
Biosensing based on field-effect transistors (FET): Recent progress and challenges.
The use of field-Effect-Transistor (FET) type biosensing arrangements has been highlighted by researchers in the field of early biomarker detection and drug screening. Their non-metalized gate dielectrics that are exposed to an electrolyte solution cover the semiconductor material and actively transduce the biological ...
advanced nanomaterial;biomarkers;biomedical analysis;biosensor;biotechnology;cancer;field-effect-transistor
Journal Article;Review
Sadighbayan, Deniz;Hasanzadeh, Mohammad;Ghafar-Zadeh, Ebrahim
10.1016/j.trac.2020.116067
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Biosensing based on field-effect transistors (FET): Recent progress and challenges. [Abstract]: The use of field-Effect-Transistor (FET) type biosensing arrangements has been highlighted by researchers in the field of early biomarker detection and drug screening. Their non-metalized gate dielectrics that are e...
32,552,867
Antimicrob Resist Infect Control
Proposal for a EN 149 acceptable reprocessing method for FFP2 respirators in times of severe shortage.
INTRODUCTION: Transmission of SARS-CoV-2 to health care workers (HCW) poses a major burden in the current COVID-19 pandemic. Unprotected exposure to a COVID-19 patient is a key risk factor for HCWs. Transmission mainly occurs by droplet transmission, or by aerosol generating procedures. Respirators such as filtering fa...
ffp2;infection control;personal protection equipment;reprocessing;respirators;sterilization
Journal Article;Research Support, Non-U.S. Gov't
Widmer, Andreas F;Richner, Gilles
10.1186/s13756-020-00744-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Proposal for a EN 149 acceptable reprocessing method for FFP2 respirators in times of severe shortage. [Abstract]: INTRODUCTION: Transmission of SARS-CoV-2 to health care workers (HCW) poses a major burden in the current COVID-19 pandemic. Unprotected exposure to a COVID-19 patient is a key risk factor for HCW...
32,609,249
Rev Soc Bras Med Trop
#StayHome: Monitoring and benchmarking social isolation trends in Caruaru and the Regiao Metropolitana do Recife during the COVID-19 pandemic.
This technical report presents information related to the Social Isolation Index (SII) of the city of Caruaru, Pernambuco, Brazil. The data was provided by In Loco, a technology startup that has collected the movement of around 60 million Brazilians through cell phone location.
Journal Article;Technical Report
Endo, Patricia Takako;Silva, Ivanovitch;Lima, Luciana;Bezerra, Leonardo;Gomes, Rafael;Ribeiro-Dantas, Marcel;Alves, Gisliany;Monteiro, Kayo Henrique de Carvalho;Lynn, Theo;Sampaio, Vanderson de Souza
10.1590/0037-8682-0271-2020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: #StayHome: Monitoring and benchmarking social isolation trends in Caruaru and the Regiao Metropolitana do Recife during the COVID-19 pandemic. [Abstract]: This technical report presents information related to the Social Isolation Index (SII) of the city of Caruaru, Pernambuco, Brazil. The data was provided by ...
32,776,551
J Med Virol
Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression.
BACKGROUND: To determine the utility of admission laboratory markers in the assessment and prognostication of coronavirus disease-2019 (COVID-19), a systematic review and meta-analysis were conducted on the association between admission laboratory values in hospitalized COVID-19 patients and subsequent disease severity...
covid-19;laboratory values;meta-analysis;meta-regression;systematic review
Journal Article;Meta-Analysis
Khinda, Jaskaran;Janjua, Naveed Z;Cheng, Shannon;van den Heuvel, Edwin R;Bhatti, Parveen;Darvishian, Maryam
10.1002/jmv.26411
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression. [Abstract]: BACKGROUND: To determine the utility of admission laboratory markers in the assessment and prognostication of coronavirus disease-2019 (COVID-19), a...
33,019,507
Vaccines (Basel)
Using the Past to Maximize the Success Probability of Future Anti-Viral Vaccines.
Rapid obtaining of safe, effective, anti-viral vaccines has recently risen to the top of the international agenda. To maximize the success probability of future anti-viral vaccines, the anti-viral vaccines successful in the past are summarized here by virus type and vaccine type. The primary focus is on viruses with bo...
sars-cov-2;immune system complexity;influenza;pandemics, virus-caused;vaccine development strategy
Journal Article
Serwer, Philip
10.3390/vaccines8040566
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Using the Past to Maximize the Success Probability of Future Anti-Viral Vaccines. [Abstract]: Rapid obtaining of safe, effective, anti-viral vaccines has recently risen to the top of the international agenda. To maximize the success probability of future anti-viral vaccines, the anti-viral vaccines successful ...
33,010,226
Am J Med
Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe.
PURPOSE: We evaluated whether the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was associated with changes in the pattern of acute cardiovascular admissions across European centers. METHODS: We set-up a multicenter, multinational, pan-European observational registry in 15 centers from 12 countr...
acute cardiovascular admissions;acute coronary syndrome;covid-19;outbreak;sars-cov2
Journal Article
Sokolski, Mateusz;Gajewski, Piotr;Zymlinski, Robert;Biegus, Jan;Berg, Jurrien M Ten;Bor, Wilbert;Braunschweig, Frieder;Caldeira, Daniel;Cuculi, Florim;D'Elia, Emilia;Edes, Istvan Ferenc;Garus, Mateusz;Greenwood, John P;Halfwerk, Frank R;Hindricks, Gerhard;Knuuti, Juhani;Kristensen, Steen Dalby;Landmesser, Ulf;Lund, Lar...
10.1016/j.amjmed.2020.08.043
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe. [Abstract]: PURPOSE: We evaluated whether the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was associated with changes in the pattern of acute cardiovas...
32,809,292
S D Med
COVID-19 Delirium with Psychosis: A Case Report.
COVID-19 typically presents as severe pneumonia often requiring intubation and ICU management. Descriptions of the potential neurological symptoms in this disease state exist, but minimal research has been conducted on the prevalence of delirium. This case report describes a patient with no past psychiatric history who...
Case Reports
Losee, Selena;Hanson, Hillary
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 Delirium with Psychosis: A Case Report. [Abstract]: COVID-19 typically presents as severe pneumonia often requiring intubation and ICU management. Descriptions of the potential neurological symptoms in this disease state exist, but minimal research has been conducted on the prevalence of delirium. Thi...
32,469,436
Electrophoresis
Physicochemical properties of SARS-CoV-2 for drug targeting, virus inactivation and attenuation, vaccine formulation and quality control.
The material properties of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its proteins are discussed. We review the viral structure, size, rigidity, lipophilicity, isoelectric point, buoyant density and centrifugation conditions, stability against pH, temperature, UV light, gamma radiation, and su...
covid-19;formulation;physicochemical properties;sars-cov;vaccine
Journal Article;Review
Scheller, Christin;Krebs, Finja;Minkner, Robert;Astner, Isabel;Gil-Moles, Maria;Watzig, Hermann
10.1002/elps.202000121
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Physicochemical properties of SARS-CoV-2 for drug targeting, virus inactivation and attenuation, vaccine formulation and quality control. [Abstract]: The material properties of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its proteins are discussed. We review the viral structure, size, ...
32,868,442
Proc Natl Acad Sci U S A
Rapid isothermal amplification and portable detection system for SARS-CoV-2.
The COVID-19 pandemic provides an urgent example where a gap exists between availability of state-of-the-art diagnostics and current needs. As assay protocols and primer sequences become widely known, many laboratories perform diagnostic tests using methods such as RT-PCR or reverse transcription loop mediated isotherm...
covid-19 diagnostics;rt-lamp;sars-cov-2;point-of-care;smartphone reader
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Ganguli, Anurup;Mostafa, Ariana;Berger, Jacob;Aydin, Mehmet Y;Sun, Fu;Ramirez, Sarah A Stewart de;Valera, Enrique;Cunningham, Brian T;King, William P;Bashir, Rashid
10.1073/pnas.2014739117
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Rapid isothermal amplification and portable detection system for SARS-CoV-2. [Abstract]: The COVID-19 pandemic provides an urgent example where a gap exists between availability of state-of-the-art diagnostics and current needs. As assay protocols and primer sequences become widely known, many laboratories per...
32,451,736
Pharm Res
Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19.
The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeuti...
sars-cov-2;ammonium chloride;antiseptic;cetylpyridinium chloride
Journal Article;Review
Baker, Nancy;Williams, Antony J;Tropsha, Alexander;Ekins, Sean
10.1007/s11095-020-02842-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19. [Abstract]: The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with...
32,841,322
Clin Infect Dis
Association between Body Mass Index and Risk of COVID-19: A Nationwide Case-Control Study in South Korea.
BACKGROUND: Increased body mass index (BMI) has been associated with higher risk of severe coronavirus disease 2019 (COVID-19) infections. However, whether obesity is a risk factor for contracting COVID-19 has been hardly investigated so far. METHODS: We examined the association between BMI level and the risk of COVID-...
covid-19;sars-cov-2;body mass index;obesity
Journal Article
Jung, Chan-Young;Park, Haeyong;Kim, Dong Wook;Lim, Hyunsun;Chang, Jung Hyun;Choi, Yoon Jung;Kim, Seong Woo;Chang, Tae Ik
10.1093/cid/ciaa1257
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Association between Body Mass Index and Risk of COVID-19: A Nationwide Case-Control Study in South Korea. [Abstract]: BACKGROUND: Increased body mass index (BMI) has been associated with higher risk of severe coronavirus disease 2019 (COVID-19) infections. However, whether obesity is a risk factor for contract...
32,683,774
Transbound Emerg Dis
Monitoring online media reports for early detection of unknown diseases: Insight from a retrospective study of COVID-19 emergence.
Event-based surveillance (EBS) systems monitor a broad range of information sources to detect early signals of disease emergence, including new and unknown diseases. In December 2019, a newly identified coronavirus emerged in Wuhan (China), causing a global coronavirus disease (COVID-19) pandemic. A retrospective study...
covid-19;padi-web;emerging disease;epidemic intelligence;one health;online news
Journal Article
Valentin, Sarah;Mercier, Alize;Lancelot, Renaud;Roche, Mathieu;Arsevska, Elena
10.1111/tbed.13738
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Monitoring online media reports for early detection of unknown diseases: Insight from a retrospective study of COVID-19 emergence. [Abstract]: Event-based surveillance (EBS) systems monitor a broad range of information sources to detect early signals of disease emergence, including new and unknown diseases. In...
32,837,888
Health Policy Technol
Telemedicine, COVID-19, and disparities: Policy implications.
While the rapid expansion of telemedicine in response to the COVID-19 pandemic highlights the impressive ability of health systems to adapt quickly to new complexities, it also raises important concerns about how to implement these novel modalities equitably. As the healthcare system becomes increasingly virtual, it ri...
covid-19;disparities;policy;telemedicine;virtual care
Journal Article
Ortega, Gezzer;Rodriguez, Jorge A;Maurer, Lydia R;Witt, Emily E;Perez, Numa;Reich, Amanda;Bates, David W
10.1016/j.hlpt.2020.08.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine, COVID-19, and disparities: Policy implications. [Abstract]: While the rapid expansion of telemedicine in response to the COVID-19 pandemic highlights the impressive ability of health systems to adapt quickly to new complexities, it also raises important concerns about how to implement these novel...
32,816,764
AJNR Am J Neuroradiol
Imaging Features of Acute Encephalopathy in Patients with COVID-19: A Case Series.
Coronavirus disease 2019 was declared a global pandemic by the World Health Organization on March 11, 2020. There is a scarcity of data on coronavirus disease 2019-related brain imaging features. We present 5 cases that illustrate varying imaging presentations of acute encephalopathy in patients with coronavirus diseas...
Journal Article
Kihira, S;Delman, B N;Belani, P;Stein, L;Aggarwal, A;Rigney, B;Schefflein, J;Doshi, A H;Pawha, P S
10.3174/ajnr.A6715
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Imaging Features of Acute Encephalopathy in Patients with COVID-19: A Case Series. [Abstract]: Coronavirus disease 2019 was declared a global pandemic by the World Health Organization on March 11, 2020. There is a scarcity of data on coronavirus disease 2019-related brain imaging features. We present 5 cases t...
32,684,166
J Ovarian Res
Withaferin A: a potential therapeutic agent against COVID-19 infection.
The outbreak and continued spread of the novel coronavirus disease 2019 (COVID-19) is a preeminent global health threat that has resulted in the infection of over 11.5 million people worldwide. In addition, the pandemic has claimed the lives of over 530,000 people worldwide. Age and the presence of underlying comorbid ...
ashwagandha;cancer;coronavirus;pandemic;withaferin a;withanolides
Journal Article;Review
Straughn, Alex R;Kakar, Sham S
10.1186/s13048-020-00684-x
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Withaferin A: a potential therapeutic agent against COVID-19 infection. [Abstract]: The outbreak and continued spread of the novel coronavirus disease 2019 (COVID-19) is a preeminent global health threat that has resulted in the infection of over 11.5 million people worldwide. In addition, the pandemic has cla...
32,420,822
Am J Bioeth
Eliminating Categorical Exclusion Criteria in Crisis Standards of Care Frameworks.
During public health crises including the COVID-19 pandemic, resource scarcity and contagion risks may require health systems to shift-to some degree-from a usual clinical ethic, focused on the well-being of individual patients, to a public health ethic, focused on population health. Many triage policies exist that fal...
allocation;coronavirus;disabilities;pandemics;rationing;triage
Journal Article
Auriemma, Catherine L;Molinero, Ashli M;Houtrow, Amy J;Persad, Govind;White, Douglas B;Halpern, Scott D
10.1080/15265161.2020.1764141
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Eliminating Categorical Exclusion Criteria in Crisis Standards of Care Frameworks. [Abstract]: During public health crises including the COVID-19 pandemic, resource scarcity and contagion risks may require health systems to shift-to some degree-from a usual clinical ethic, focused on the well-being of individu...
32,718,042
Vaccines (Basel)
New Points of Departure for More Global Influenza Vaccine Use.
Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to year. The narrow specificity of conventional vaccines and the drug resistance of curr...
covid-19 pandemic;cross protectivity;inactivated vaccines;influenza;live attenuated vaccines;next-generation vaccines;synthetic vaccines
Editorial
Kiseleva, Irina
10.3390/vaccines8030410
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: New Points of Departure for More Global Influenza Vaccine Use. [Abstract]: Each year, influenza causes a significant acute respiratory disease burden. In addition, influenza pandemics periodically occur. Annual vaccination is the best tool for influenza prevention, but its effectiveness can vary from year to y...
33,055,229
Clin Microbiol Rev
Immunopathogenesis of Coronavirus-Induced Acute Respiratory Distress Syndrome (ARDS): Potential Infection-Associated Hemophagocytic Lymphohistiocytosis.
The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 in Wuhan, China, introduced the third highly pathogenic coronavirus into humans in the 21st century. Scientific advance after the severe acute respiratory syndrome coronavirus (SARS-CoV) epidemic and Middle East respiratory syndrome coronavirus (MERS-...
acute respiratory distress syndrome;hemophagocytic lymphohistiocytosis;human coronavirus
Journal Article;Research Support, Non-U.S. Gov't;Review
Quan, Chao;Li, Caiyan;Ma, Han;Li, Yisha;Zhang, Huali
10.1128/CMR.00074-20
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Immunopathogenesis of Coronavirus-Induced Acute Respiratory Distress Syndrome (ARDS): Potential Infection-Associated Hemophagocytic Lymphohistiocytosis. [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 in Wuhan, China, introduced the third highly pathogenic coronavirus into huma...
32,520,513
Clin Nucl Med
Atypical Presentation of COVID-19 Incidentally Detected at 18F-FDG PET/CT in an Asymptomatic Oncological Patient.
The incidence of COVID-19, a severe acute respiratory syndrome caused by SARS-CoV-2, is rapidly growing worldwide. In this pandemic period, the chance of incidental pulmonary findings suggestive of COVID-19 at F-FDG PET/CT in asymptomatic oncological patients is not negligible. To suspect COVID-19 is more demanding whe...
Case Reports;Journal Article
Mattoli, Maria Vittoria;Taralli, Silvia;Pennese, Elsa;D'Angelo, Carla;Angrilli, Francesco;Villano, Carlo
10.1097/RLU.0000000000003175
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Atypical Presentation of COVID-19 Incidentally Detected at 18F-FDG PET/CT in an Asymptomatic Oncological Patient. [Abstract]: The incidence of COVID-19, a severe acute respiratory syndrome caused by SARS-CoV-2, is rapidly growing worldwide. In this pandemic period, the chance of incidental pulmonary findings s...
32,574,894
Am J Otolaryngol
Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic.
SARS CoV 2 is very much homologous in structure to SARS CoV. Review of literature suggests the in-vitro virucidal action of povidone iodine in SARS CoV and MERS. The oropharynx and nasopharynx are target sites of SARS CoV 2. A significant proportion of COVID 19 sufferers are asymptomatic, but shedding these viral parti...
gargles;mers;nasal spray;povidone iodine;prophylaxis;sars cov 2;sars cov
Journal Article
Khan, Mubarak Muhamed;Parab, Sapna Ramkrishna;Paranjape, Mandar
10.1016/j.amjoto.2020.102618
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic. [Abstract]: SARS CoV 2 is very much homologous in structure to SARS CoV. Review of literature suggests the in-vitro virucidal action of povidone iodine in SARS CoV and MERS. The oropharynx and nasopharynx are target...
32,774,121
Biochem Med (Zagreb)
SARS-CoV-2 - a new challenge for laboratory medicine.
The new corona virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) causes a disease called COVID-19 (coronavirus disease 2019), that develops mostly in subjects with already impaired immune system function, primarily in the elderly and in individuals with some chronic disease or condition. The reasons f...
covid-19;sars-cov-2;biomarkers;laboratory medicine;patient safety
Journal Article;Review
Dodig, Slavica;Cepelak, Ivana;Cepelak Dodig, Daniela;Laskaj, Renata
10.11613/BM.2020.030503
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 - a new challenge for laboratory medicine. [Abstract]: The new corona virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) causes a disease called COVID-19 (coronavirus disease 2019), that develops mostly in subjects with already impaired immune system function, primarily in the elder...
32,972,320
J Am Heart Assoc
High Prevalence of Acquired Thrombophilia Without Prognosis Value in Patients With Coronavirus Disease 2019.
Background Recent literature reports a strong thrombotic tendency in patients hospitalized for a coronavirus disease 2019 (COVID-19) infection. This characteristic is unusual and seems specific to COVID-19 infections, especially in their severe form. Viral infections can trigger acquired thrombophilia, which can then l...
coronavirus disease 2019;thrombophilia;thrombosis
Journal Article
Ferrari, Emile;Sartre, Benjamin;Squara, Fabien;Contenti, Julie;Occelli, Celine;Lemoel, Fabien;Levraut, Jacques;Doyen, Denis;Dellamonica, Jean;Mondain, Veronique;Chirio, David;Risso, Karine;Cua, Eric;Orban, Jean Christophe;Ichai, Carole;Labbaoui, Mohamed;Mossaz, Baptiste;Moceri, Pamela;Appert-Flory, Anny;Fischer, Floren...
10.1161/JAHA.120.017773
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: High Prevalence of Acquired Thrombophilia Without Prognosis Value in Patients With Coronavirus Disease 2019. [Abstract]: Background Recent literature reports a strong thrombotic tendency in patients hospitalized for a coronavirus disease 2019 (COVID-19) infection. This characteristic is unusual and seems speci...
32,976,118
J Clin Invest
Corticosteroids, COVID-19 pneumonia, and acute respiratory distress syndrome.
Although corticosteroids dampen the dysregulated immune system and sometimes are prescribed as an adjunctive treatment for pneumonia, their effectiveness in the treatment of coronavirus disease 2019 (COVID-19) remains controversial. In this issue of the JCI, Liu and Zhang et al. evaluated corticosteroid treatment in mo...
Journal Article;Research Support, N.I.H., Extramural;Comment
Matthay, Michael A;Wick, Katherine D
10.1172/JCI143331
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Corticosteroids, COVID-19 pneumonia, and acute respiratory distress syndrome. [Abstract]: Although corticosteroids dampen the dysregulated immune system and sometimes are prescribed as an adjunctive treatment for pneumonia, their effectiveness in the treatment of coronavirus disease 2019 (COVID-19) remains con...
32,537,480
Data Brief
ARIMA modelling and forecasting of irregularly patterned COVID-19 outbreaks using Japanese and South Korean data.
The World Health Organization (WHO) upgraded the status of the coronavirus disease 2019 (COVID-19) outbreak from epidemic to global pandemic on March 11, 2020. Various mathematical and statistical models have been proposed to predict the spread of COVID-2019 [1]. We collated data on daily new confirmed cases of the COV...
daily new cases;dynamic prediction;statistical analysis;stationarity
Journal Article
Duan, Xingde;Zhang, Xiaolei
10.1016/j.dib.2020.105779
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: ARIMA modelling and forecasting of irregularly patterned COVID-19 outbreaks using Japanese and South Korean data. [Abstract]: The World Health Organization (WHO) upgraded the status of the coronavirus disease 2019 (COVID-19) outbreak from epidemic to global pandemic on March 11, 2020. Various mathematical and ...
32,422,376
Int J Infect Dis
Interleukin-1 receptor antagonist anakinra in association with remdesivir in severe COVID-19: A case report.
We report the first successful treatment with the IL-1 receptor antagonist anakinra, in association with the most promising and available antiviral therapy, of a severe case of novel coronavirus disease 2019 (COVID-19). We describe the diagnosis, clinical course, and management of the case, including the respiratory fa...
anakinra;cytokine-release syndrome;interleukin-1 receptor antagonist;novel coronavirus disease 2019 (covid-19);remdesivir
Case Reports
Franzetti, Marco;Pozzetti, Ugo;Carugati, Manuela;Pandolfo, Alessandro;Molteni, Chiara;Faccioli, Paolo;Castaldo, Gioacchino;Longoni, Ernesto;Ormas, Valentina;Iemoli, Enrico;Piconi, Stefania
10.1016/j.ijid.2020.05.050
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Interleukin-1 receptor antagonist anakinra in association with remdesivir in severe COVID-19: A case report. [Abstract]: We report the first successful treatment with the IL-1 receptor antagonist anakinra, in association with the most promising and available antiviral therapy, of a severe case of novel coronav...
32,240,078
Emerg Infect Dis
COVID-19 Outbreak Associated with Air Conditioning in Restaurant, Guangzhou, China, 2020.
During January 26-February 10, 2020, an outbreak of 2019 novel coronavirus disease in an air-conditioned restaurant in Guangzhou, China, involved 3 family clusters. The airflow direction was consistent with droplet transmission. To prevent the spread of the virus in restaurants, we recommend increasing the distance bet...
2019 novel coronavirus disease;covid-19;sars-cov-2;droplet transmission;family cluster;outbreak;respiratory infections;restaurant;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Journal Article
Lu, Jianyun;Gu, Jieni;Li, Kuibiao;Xu, Conghui;Su, Wenzhe;Lai, Zhisheng;Zhou, Deqian;Yu, Chao;Xu, Bin;Yang, Zhicong
10.3201/eid2607.200764
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: COVID-19 Outbreak Associated with Air Conditioning in Restaurant, Guangzhou, China, 2020. [Abstract]: During January 26-February 10, 2020, an outbreak of 2019 novel coronavirus disease in an air-conditioned restaurant in Guangzhou, China, involved 3 family clusters. The airflow direction was consistent with dr...
32,471,013
Liver Int
Low prevalence and disease severity of COVID-19 in post-liver transplant recipients-A single centre experience.
Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is driving a present day global pandemic. Immunosuppressed patients are regarded as a high-risk cohort. The following is a short report on COVID-19 in liver transplant recipients (n = 5)...
covid-19;immunosuppression;liver transplant
Journal Article
Verma, Anita;Khorsandi, Shirin Elizabeth;Dolcet, Annalisa;Prachalias, Andreas;Suddle, Abid;Heaton, Nigel;Jassem, Wayel
10.1111/liv.14552
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Low prevalence and disease severity of COVID-19 in post-liver transplant recipients-A single centre experience. [Abstract]: Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is driving a present day global pandemic. Immunosuppr...