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32,999,543 | J Clin Orthop Trauma | Is it safe to restart elective day-case surgery? Lessons learned from upper limb ambulatory trauma during the COVID-19 pandemic. | Background: The COVID-19 pandemic has impacted on the provision of elective and trauma orthopaedic surgery worldwide with millions of operations cancelled. The risk of patients developing COVID-19 after undergoing ambulatory procedures in hospitals is unknown. This paper aims to investigate the risk of developing COVID... | ambulatory trauma;covid-19;elective surgery | Journal Article | Trowbridge, Samuel;Wignadasan, Warran;Davenport, Dominic;Sarker, Shahrier;Hunter, Alistair;Gidwani, Sam | 10.1016/j.jcot.2020.07.023 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Is it safe to restart elective day-case surgery? Lessons learned from upper limb ambulatory trauma during the COVID-19 pandemic. [Abstract]: Background: The COVID-19 pandemic has impacted on the provision of elective and trauma orthopaedic surgery worldwide with millions of operations cancelled. The risk of pa... |
33,002,827 | Phytomedicine | Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3. | BACKGROUND: Vascular endothelial activation is pivotal for the pathological development of various infectious and inflammatory diseases. Therapeutic interventions to prevent endothelial activation are of great clinical significance to achieve anti-inflammatory strategy. Previous studies indicate that the total flavonoi... | calcineurin/nfatc3;endothelial cell inflammation;rhamnocitrin;soce | Journal Article | Lin, Tong;Luo, Wenwei;Li, Ziqing;Zhang, Lili;Zheng, Xinghan;Mai, Liting;Yang, Wanqi;Guan, Guimei;Su, Ziren;Liu, Peiqing;Li, Zhuoming;Xie, Youliang | 10.1016/j.phymed.2020.153350 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3. [Abstract]: BACKGROUND: Vascular endothelial activation is pivotal for the pathological development of various infectious and inflammatory diseases. Therapeutic interventions to prevent endothe... |
32,770,768 | J Med Virol | The role of DBP gene polymorphisms in the prevalence of new coronavirus disease 2019 infection and mortality rate. | Since December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has given rise to emerging respiratory infections with pandemic diffusion. The vitamin D binding protein (DBP) with emphasis on its regulation of total and free vitamin D metabolite levels participate in... | coronavirus disease 2019;polymorphism;rs4588;rs7041;vitamin d binding protein | Journal Article | Karcioglu Batur, Lutfiye;Hekim, Nezih | 10.1002/jmv.26409 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: The role of DBP gene polymorphisms in the prevalence of new coronavirus disease 2019 infection and mortality rate. [Abstract]: Since December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has given rise to emerging respiratory infections with pandemic dif... |
33,043,879 | Disaster Med Public Health Prep | The Role of Israel's Emergency Medical Services During a Pandemic in the Pre-Exposure Period. | OBJECTIVE: The scientific literature on coronavirus disease (COVID-19) is extensive, but little is written about the role of emergency medical services (EMS). The objective of this study is to describe the role of Magen David Adom (MDA), Israel's national emergency prehospital medical organization, in the pre-exposure ... | covid-19;coronavirus;emergency medical services;epidemics;pandemics | Journal Article | Jaffe, Eli;Sonkin, Roman;Podolsky, Timna;Alpert, Evan Avraham;Siman-Tov, Maya | 10.1017/dmp.2020.369 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The Role of Israel's Emergency Medical Services During a Pandemic in the Pre-Exposure Period. [Abstract]: OBJECTIVE: The scientific literature on coronavirus disease (COVID-19) is extensive, but little is written about the role of emergency medical services (EMS). The objective of this study is to describe the... |
32,562,070 | Clin Rheumatol | A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab. | Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA). Tocilizumab was applied and intended to target both COVID-19 and RA. However, disease of this patient aggravated after usage of tociliz... | coronavirus disease 2019;rheumatoid arthritis;secondary opportunistic infection;tocilizumab | Case Reports;Journal Article;Review | Cai, Shaozhe;Sun, Wei;Li, Ming;Dong, Lingli | 10.1007/s10067-020-05234-w | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab. [Abstract]: Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA). Tocilizumab was applied and intended t... |
32,350,584 | Int Orthop | Epidemiologic characteristics of traumatic fractures in elderly patients during the outbreak of coronavirus disease 2019 in China. | PURPOSE: This study aimed to describe the epidemiologic characteristics of fracture in the elderly during the COVID-19. METHODS: This was a retrospective multi-centre study, which included patients who sustained fractures between 20 January and 19 February 2020. The collected data included patients' demographics (age a... | covid-19;elderly;epidemiology;fracture;pandemic | Journal Article | Zhu, Yanbin;Chen, Wei;Xin, Xing;Yin, Yingchao;Hu, Jinglve;Lv, Hongzhi;Li, Weixu;Deng, Xiangtian;Zhu, Chao;Zhu, Jian;Zhang, Jinli;Ye, Fagang;Chen, Aimin;Wu, Zhanyong;Ma, Zhanbei;Zhang, Xinhu;Gao, Fengmei;Li, Jidong;Wang, Conglin;Zhang, Yingze;Hou, Zhiyong | 10.1007/s00264-020-04575-0 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Epidemiologic characteristics of traumatic fractures in elderly patients during the outbreak of coronavirus disease 2019 in China. [Abstract]: PURPOSE: This study aimed to describe the epidemiologic characteristics of fracture in the elderly during the COVID-19. METHODS: This was a retrospective multi-centre s... |
32,673,562 | Cell Syst | RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. | SARS-CoV-2 genomic and subgenomic RNA (sgRNA) transcripts hijack the host cell's machinery. Subcellular localization of its viral RNA could, thus, play important roles in viral replication and host antiviral immune response. We perform computational modeling of SARS-CoV-2 viral RNA subcellular residency across eight su... | apex-seq;cox4;sars-cov-2;double-membrane vesicle;hypothesis generation;machine learning model;proximity labelling;viral rna localization | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Wu, Kevin E;Fazal, Furqan M;Parker, Kevin R;Zou, James;Chang, Howard Y | 10.1016/j.cels.2020.06.008 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. [Abstract]: SARS-CoV-2 genomic and subgenomic RNA (sgRNA) transcripts hijack the host cell's machinery. Subcellular localization of its viral RNA could, thus, play important roles in viral replication and host antiviral immune respon... |
32,972,339 | Curr Drug Targets | Targeting host cell proteases to prevent SARS-CoV-2 invasion. | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread worldwide and caused widespread devastation. In the absence of definitive therapy, symptomatic management remains the standard of care. Repurposing of many existing drugs including several anti-viral drugs is being attempted to tackle the COVID-19 ... | covid-19;tmprss;cathepsin;chloroquine;furin;plasmin | Journal Article;Review | Kaur, Upinder;Chakrabarti, Sankha Shubhra;Ojha, Bisweswar;Pathak, Bhairav Kumar;Singh, Amit;Saso, Luciano;Chakrabarti, Sasanka | 10.2174/1389450121666200924113243 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Targeting host cell proteases to prevent SARS-CoV-2 invasion. [Abstract]: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread worldwide and caused widespread devastation. In the absence of definitive therapy, symptomatic management remains the standard of care. Repurposing of many existing ... |
32,836,704 | Build Environ | Trajectories of large respiratory droplets in indoor environment: A simplified approach. | The recent pandemic of COVID-19 has brought about tremendous impact on every aspect of human activities all over the world. The main route of transmission is believed to be through coronavirus-bearing respiratory droplets. The respiratory droplets have a wide spectrum in droplet size, ranging from very small droplets (... | covid-19;droplet trajectory;indoor environment;numerical;respiratory droplets;social distancing | Journal Article | Cheng, C H;Chow, C L;Chow, W K | 10.1016/j.buildenv.2020.107196 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: Trajectories of large respiratory droplets in indoor environment: A simplified approach. [Abstract]: The recent pandemic of COVID-19 has brought about tremendous impact on every aspect of human activities all over the world. The main route of transmission is believed to be through coronavirus-bearing respirato... |
32,311,651 | Diabetes Metab Syndr | Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may be harmful in patients with diabetes during COVID-19 pandemic. | The novel coronavirus disease 2019 (COVID-19) outbreak once again demonstrated the importance of the renin-angiotensin system (RAS) in patients with diabetes. Activation of the RAS increases in patients with diabetes. The virus attaches to the ACE2 enzyme at low cytosolic pH values and enters into the cell and causes i... | angiotensin converting enzyme inhibitors;angiotensin receptor antagonists;diabetes mellitus;novel coronavirus disease 2019 (covid-19);renin-angiotensin system | Letter | Cure, Erkan;Cumhur Cure, Medine | 10.1016/j.dsx.2020.04.019 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may be harmful in patients with diabetes during COVID-19 pandemic. [Abstract]: The novel coronavirus disease 2019 (COVID-19) outbreak once again demonstrated the importance of the renin-angiotensin system (RAS) in patients with diabetes... |
32,591,665 | Evid Based Dent | Can orthodontic care be safely delivered during the COVID-19 pandemic? Recommendations from a literature review. | Data sources Five electronic databases were searched: COVID-19 Open Research Dataset (CORD-19-2020); PubMed; MEDLINE; Scopus; and Google Scholar.Study selection Titles of articles and abstracts were identified during the electronic database searches and then screened for relevance. Publications up until the date of the... | Journal Article;Comment | Carter, Annabelle | 10.1038/s41432-020-0103-9 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Can orthodontic care be safely delivered during the COVID-19 pandemic? Recommendations from a literature review. [Abstract]: Data sources Five electronic databases were searched: COVID-19 Open Research Dataset (CORD-19-2020); PubMed; MEDLINE; Scopus; and Google Scholar.Study selection Titles of articles and ab... | |
32,281,328 | Zhongguo Zhong Yao Za Zhi | [Study on screening potential traditional Chinese medicines against 2019-nCoV based on Mpro and PLP]. | With the rapid outbreak of COVID-19, traditional Chinese medicine(TCM) has been playing an active role against the epidemic. However, the screening of TCM is limited by the development cycle and laboratory conditions, which greatly limits the screening speed. This study established optimization docking models and virtu... | 2019-ncov;3cl hydrolase;angiotensin converting enzyme 2;molecular docking;papain-like protease;traditional chinese medicine | Journal Article | Ma, Jing;Huo, Xiao-Qian;Chen, Xi;Zhu, Wei-Xing;Yao, Mei-Cun;Qiao, Yan-Jiang;Zhang, Yan-Ling | 10.19540/j.cnki.cjcmm.20200216.401 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: [Study on screening potential traditional Chinese medicines against 2019-nCoV based on Mpro and PLP]. [Abstract]: With the rapid outbreak of COVID-19, traditional Chinese medicine(TCM) has been playing an active role against the epidemic. However, the screening of TCM is limited by the development cycle and la... |
32,835,962 | Sci Total Environ | SARS-CoV-2 has been circulating in northern Italy since December 2019: Evidence from environmental monitoring. | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease COVID-19, a public health emergency worldwide, and Italy is among the most severely affected countries. The first autochthonous Italian case of COVID-19 was documented on February 21, 2020. We investigated the possib... | covid-19;coronavirus;sars-cov-2;sewage;surveillance;wastewater | Journal Article | La Rosa, Giuseppina;Mancini, Pamela;Bonanno Ferraro, Giusy;Veneri, Carolina;Iaconelli, Marcello;Bonadonna, Lucia;Lucentini, Luca;Suffredini, Elisabetta | 10.1016/j.scitotenv.2020.141711 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: SARS-CoV-2 has been circulating in northern Italy since December 2019: Evidence from environmental monitoring. [Abstract]: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease COVID-19, a public health emergency worldwide, and Italy is among the most severely ... |
32,905,053 | Nonlinear Dyn | Human mobility and COVID-19 initial dynamics. | Countries in Europe took different mobility containment measures to curb the spread of COVID-19. The European Commission asked mobile network operators to share on a voluntarily basis anonymised and aggregate mobile data to improve the quality of modelling and forecasting for the pandemic at EU level. In fact, mobility... | covid-19 dynamics;coronavirus;human mobility;mobility data | Journal Article | Iacus, Stefano Maria;Santamaria, Carlos;Sermi, Francesco;Spyratos, Spyros;Tarchi, Dario;Vespe, Michele | 10.1007/s11071-020-05854-6 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Human mobility and COVID-19 initial dynamics. [Abstract]: Countries in Europe took different mobility containment measures to curb the spread of COVID-19. The European Commission asked mobile network operators to share on a voluntarily basis anonymised and aggregate mobile data to improve the quality of modell... |
32,414,182 | J Clin Med | Unrealistic Optimism in the Time of Coronavirus Pandemic: May It Help to Kill, If So-Whom: Disease or the Person? | Objective: The results of numerous empirical studies have showed the occurrence of so-called unrealistic optimism. Thus, we aimed to investigate whether in the situation of an imminent coronavirus pandemic, people would still perceive themselves as being less exposed to the disease than others. Methods: Survey studies ... | healthy illusion;risk perception;threat and fear;unrealistic optimism;unrealistic pessimism | Journal Article | Dolinski, Dariusz;Dolinska, Barbara;Zmaczynska-Witek, Barbara;Banach, Maciej;Kulesza, Wojciech | 10.3390/jcm9051464 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Unrealistic Optimism in the Time of Coronavirus Pandemic: May It Help to Kill, If So-Whom: Disease or the Person? [Abstract]: Objective: The results of numerous empirical studies have showed the occurrence of so-called unrealistic optimism. Thus, we aimed to investigate whether in the situation of an imminent ... |
32,773,414 | Indian J Med Res | Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. | Background & objectives: In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations and outcomes of this disease (COVID-19) have been reported from different countries. The present study was aimed to describe the clinico-demo... | covid-19;clinico-epidemiologic;cough;north india;outcome;prospective | Journal Article | Mohan, Anant;Tiwari, Pawan;Bhatnagar, Sushma;Patel, Ankit;Maurya, Abhishek;Dar, Lalit;Pahuja, Sourabh;Garg, Rakesh;Gupta, Nishkarsh;Sahoo, Biswajeet;Gupta, Ritu;Meena, Ved Prakash;Vig, Saurabh;Pandit, Anuja;Mittal, Saurabh;Madan, Karan;Hadda, Vijay;Dwivedi, Tanima;Choudhary, Aashish;Brijwal, Megha;Soneja, Manish;Guleri... | 10.4103/ijmr.IJMR_1788_20 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. [Abstract]: Background & objectives: In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations ... |
32,637,278 | Cureus | Packed Red Blood Cell Transfusion as a Potential Treatment Option in COVID-19 Patients With Hypoxemic Respiratory Failure: A Case Report. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19), an ongoing pandemic that started as an outbreak in China. The clinical picture varies from asymptomatic or mild cases to critically ill patients. Most of the critically ill patients present with hypoxia due... | covid-19;hemoglobin;hypoxemia;novel coronavirus;packed red blood cell transfusion;rbc;red blood cells;sars-cov-2 | Case Reports | Ejigu, Teshager;Patel, Nikunjkumar;Sharma, Anuradha;Vanjarapu, Jagan Mohan Rao;Nookala, Vinod | 10.7759/cureus.8398 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Packed Red Blood Cell Transfusion as a Potential Treatment Option in COVID-19 Patients With Hypoxemic Respiratory Failure: A Case Report. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19), an ongoing pandemic that started as an outbreak... |
32,584,779 | J Med Internet Res | Influence of Mass and Social Media on Psychobehavioral Responses Among Medical Students During the Downward Trend of COVID-19 in Fujian, China: Cross-Sectional Study. | BACKGROUND: An extensive amount of information related to the novel coronavirus (COVID-19) pandemic was disseminated by mass and social media in China. To date, there is limited evidence on how this infodemic may influence psychobehavioral responses to the crisis. OBJECTIVE: The aim of this study is to assess the psych... | covid-19;china;mass media;medical students;psychobehavioral;social media | Journal Article;Research Support, Non-U.S. Gov't | Lin, Yulan;Hu, Zhijian;Alias, Haridah;Wong, Li Ping | 10.2196/19982 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Influence of Mass and Social Media on Psychobehavioral Responses Among Medical Students During the Downward Trend of COVID-19 in Fujian, China: Cross-Sectional Study. [Abstract]: BACKGROUND: An extensive amount of information related to the novel coronavirus (COVID-19) pandemic was disseminated by mass and soc... |
32,392,859 | Diagnostics (Basel) | SARS-CoV-2 Infection with Different Radiological Insights. | Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) is a novel viral infection characterized by several symptoms range from mild to severe clinical conditions that could lead to death. We report two different radiological findings on computed tomography (CT) in two patients affected by SARS-CoV-2: a lung acute... | acute respiratory distress syndrome;lung acute embolism;severe acute respiratory syndrome-coronavirus-2 | Case Reports | Brogna, Barbara;Brogna, Claudia;Martino, Alberigo;Minichiello, Stefana;Romeo, Domenico M;Romano, Paolo;Bignardi, Elio;Mazza, Emerico Maria;Musto, Lanfranco | 10.3390/diagnostics10050283 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: SARS-CoV-2 Infection with Different Radiological Insights. [Abstract]: Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) is a novel viral infection characterized by several symptoms range from mild to severe clinical conditions that could lead to death. We report two different radiological findings ... |
32,307,014 | Mil Med Res | Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19. | Since December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44%. Studies have shown that coagulation dysfunction is a major cause of de... | covid-19;coagulation dysfunction;diagnosis;severe;treatment | Journal Article | Song, Jing-Chun;Wang, Gang;Zhang, Wei;Zhang, Yang;Li, Wei-Qin;Zhou, Zhou | 10.1186/s40779-020-00247-7 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19. [Abstract]: Since December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, wit... |
32,354,360 | Crit Care | Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China. | BACKGROUND: In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. METHODS: Retrospective case series of COVID-19 patie... | coronavirus;infection;pneumonia | Journal Article;Research Support, Non-U.S. Gov't | Wang, Dawei;Yin, Yimei;Hu, Chang;Liu, Xing;Zhang, Xingguo;Zhou, Shuliang;Jian, Mingzhi;Xu, Haibo;Prowle, John;Hu, Bo;Li, Yirong;Peng, Zhiyong | 10.1186/s13054-020-02895-6 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China. [Abstract]: BACKGROUND: In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of ... |
32,744,561 | J Nutr Health Aging | COVID-19, Virology and Geroscience: A Perspective. | A new coronavirus, called SARS-CoV-2, was identified in Wuhan, China, in December 2019. The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease 2019 (COVID-19). Older adults have higher peak of viral load and, especially those with comorbidities, had higher COVID-19-related fatality rates tha... | covid-19;sars-cov-2;aging;coronavirus;frailty;geroscience;prevention | Journal Article;Review | Vellas, C;Delobel, P;de Souto Barreto, P;Izopet, J | 10.1007/s12603-020-1416-2 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: COVID-19, Virology and Geroscience: A Perspective. [Abstract]: A new coronavirus, called SARS-CoV-2, was identified in Wuhan, China, in December 2019. The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease 2019 (COVID-19). Older adults have higher peak of viral load and, especially ... |
32,769,063 | Mult Scler Relat Disord | Effects of MS disease-modifying therapies on responses to vaccinations: A review. | BACKGROUND: Development of long-term immunologic memory relies upon humoral and cellular immune responses. Vaccinations aim to stimulate these responses against pathogens. Several studies have evaluated the impact of multiple sclerosis disease-modifying therapies on immune response to vaccines. Findings from these stud... | disease-modifying therapies;multiple sclerosis;vaccines | Journal Article;Review | Ciotti, John Robert;Valtcheva, Manouela V;Cross, Anne Haney | 10.1016/j.msard.2020.102439 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Effects of MS disease-modifying therapies on responses to vaccinations: A review. [Abstract]: BACKGROUND: Development of long-term immunologic memory relies upon humoral and cellular immune responses. Vaccinations aim to stimulate these responses against pathogens. Several studies have evaluated the impact of ... |
33,013,676 | Front Neurol | Myasthenia Gravis and COVID-19: Clinical Characteristics and Outcomes. | Myasthenia gravis (MG), an autoimmune neuromuscular disorder, may be a risk factor for severe COVID-19. We conducted an observational retrospective study with 15 consecutive adult MG patients admitted with COVID-19 at four hospitals in Sao Paulo, Brazil. Most patients with MG hospitalized for COVID-19 had severe course... | covid-19;myasthenia gravis;sars-cov-2;immunosuppression;neuromuscular disorders | Journal Article | Camelo-Filho, Antonio E;Silva, Andre M S;Estephan, Eduardo P;Zambon, Antonio A;Mendonca, Rodrigo H;Souza, Paulo V S;Pinto, Wladimir B V R;Oliveira, Acary S B;Dangoni-Filho, Iron;Pouza, Ana F P;Valerio, Berenice C O;Zanoteli, Edmar | 10.3389/fneur.2020.01053 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Myasthenia Gravis and COVID-19: Clinical Characteristics and Outcomes. [Abstract]: Myasthenia gravis (MG), an autoimmune neuromuscular disorder, may be a risk factor for severe COVID-19. We conducted an observational retrospective study with 15 consecutive adult MG patients admitted with COVID-19 at four hospi... |
32,129,670 | Can Assoc Radiol J | CT Imaging and Differential Diagnosis of COVID-19. | Since the beginning of 2020, coronavirus disease 2019 (COVID-19) has spread throughout China. This study explains the findings from lung computed tomography images of some patients with COVID-19 treated in this medical institution and discusses the difference between COVID-19 and other lung diseases. | 2019n-cov;covid19;ct;lung diseases;pneumonia | Case Reports;Journal Article | Dai, Wei-Cai;Zhang, Han-Wen;Yu, Juan;Xu, Hua-Jian;Chen, Huan;Luo, Si-Ping;Zhang, Hong;Liang, Li-Hong;Wu, Xiao-Liu;Lei, Yi;Lin, Fan | 10.1177/0846537120913033 | [
0,
1,
0,
1,
0,
0,
0
] | [Title]: CT Imaging and Differential Diagnosis of COVID-19. [Abstract]: Since the beginning of 2020, coronavirus disease 2019 (COVID-19) has spread throughout China. This study explains the findings from lung computed tomography images of some patients with COVID-19 treated in this medical institution and discusses the... |
32,761,535 | Sleep Breath | Invasive mechanical ventilation using a bilevel PAP ST device in a healthy swine model. | PURPOSE: The Coronavirus Disease 2019 (COVID-19) pandemic may cause an acute shortage of ventilators. Standard noninvasive bilevel positive airway pressure devices with spontaneous and timed respirations (bilevel PAP ST) could provide invasive ventilation but evidence on their effectiveness in this capacity is limited.... | animal;bilevel positive airway pressure;continuous positive airway pressure;coronavirus;mechanical;models;respiratory mechanics;ventilators | Journal Article | Foster, Brian E;Diaz-Abad, Montserrat;Hudson, Arlene J;Bedocs, Peter;Doll, Darius M;Lopez, Steven A;Mares, John;Hutzler, Justin;Robertson, Brian D | 10.1007/s11325-020-02141-x | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Invasive mechanical ventilation using a bilevel PAP ST device in a healthy swine model. [Abstract]: PURPOSE: The Coronavirus Disease 2019 (COVID-19) pandemic may cause an acute shortage of ventilators. Standard noninvasive bilevel positive airway pressure devices with spontaneous and timed respirations (bileve... |
32,426,212 | Cell Rep | Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections. | The World Health Organization has declared the ongoing outbreak of COVID-19, which is caused by a novel coronavirus SARS-CoV-2, a pandemic. There is currently a lack of knowledge about the antibody response elicited from SARS-CoV-2 infection. One major immunological question concerns antigenic differences between SARS-... | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Lv, Huibin;Wu, Nicholas C;Tsang, Owen Tak-Yin;Yuan, Meng;Perera, Ranawaka A P M;Leung, Wai Shing;So, Ray T Y;Chan, Jacky Man Chun;Yip, Garrick K;Chik, Thomas Shiu Hong;Wang, Yiquan;Choi, Chris Yau Chung;Lin, Yihan;Ng, Wilson W;Zhao, Jincun;Poon, Leo L M;Peiris, J S Malik;Wilson, Ian A;Mok, Chris K P | 10.1016/j.celrep.2020.107725 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections. [Abstract]: The World Health Organization has declared the ongoing outbreak of COVID-19, which is caused by a novel coronavirus SARS-CoV-2, a pandemic. There is currently a lack of knowledge about the antibody response elicited from S... | |
32,374,546 | Rev Med Suisse | [Medical students at the bedside of COVID-19 patients : motivations and challenges]. | The SARS-CoV-2 pandemic is putting our healthcare system under exceptional pressure, given the number of affected patients. In a context of limited human healthcare resources, senior medical students represent a valuable workforce that can quickly be mobilized for patient care. This is the approach followed in Switzerl... | Journal Article | Aebischer, Oriane;Porret, Raphael;Pawlowska, Victoria;Barbier, Jeanne;Caratsch, Leo;Moreira De Jesus, Mike;Castioni, Julien;Kraege, Vanessa;Bart, Pierre-Alexandre;Mean, Marie;Monti, Matteo;Garnier, Antoine;Vollenweider, Peter;Gachoud, David | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [Medical students at the bedside of COVID-19 patients : motivations and challenges]. [Abstract]: The SARS-CoV-2 pandemic is putting our healthcare system under exceptional pressure, given the number of affected patients. In a context of limited human healthcare resources, senior medical students represent a va... | ||
32,409,498 | Diabetes Care | Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication. | OBJECTIVE: Diabetes is one of the most distinct comorbidities of COVID-19. Here, we describe the clinical characteristics of and outcomes in patients with diabetes in whom COVID-19 was confirmed or clinically diagnosed (with typical features on lung imaging and symptoms) and their association with glucose-lowering or b... | Journal Article;Research Support, Non-U.S. Gov't | Chen, Yuchen;Yang, Dong;Cheng, Biao;Chen, Jian;Peng, Anlin;Yang, Chen;Liu, Chong;Xiong, Mingrui;Deng, Aiping;Zhang, Yu;Zheng, Ling;Huang, Kun | 10.2337/dc20-0660 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication. [Abstract]: OBJECTIVE: Diabetes is one of the most distinct comorbidities of COVID-19. Here, we describe the clinical characteristics of and outcomes in patients with diabetes in whom C... | |
32,291,076 | Biochem Biophys Res Commun | EZH2-mediated H3K27me3 inhibits ACE2 expression. | The outbreak of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is spreading globally and quickly, leading to emerging health issues. SARS-CoV-2 enters into and infects host cells through its spike glycoprotein recognizing the cell receptor Angiotensin-converting enzyme II (ACE2). Here, we noticed t... | ace2;coronavirus;ezh2;h3.3;sars-cov-2 | Journal Article;Research Support, Non-U.S. Gov't | Li, Yuanyuan;Li, Honggang;Zhou, Liquan | 10.1016/j.bbrc.2020.04.010 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: EZH2-mediated H3K27me3 inhibits ACE2 expression. [Abstract]: The outbreak of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is spreading globally and quickly, leading to emerging health issues. SARS-CoV-2 enters into and infects host cells through its spike glycoprotein recognizing the cel... |
32,891,011 | Diabetes Metab Syndr | Impact of COVID-19 and comorbidities on health and economics: Focus on developing countries and India. | BACKGROUND AND AIMS: Presence of comorbidities in patients with Coronavirus disease 2019 (COVID-19) have often been associated with increased in-hospital complications and mortality. Intriguingly, several developed countries with a higher quality of life have relatively higher mortality with COVID-19, compared to the m... | covid-19;comorbidities;developing countries;economics;health | Journal Article;Review | Singh, Awadhesh Kumar;Misra, Anoop | 10.1016/j.dsx.2020.08.032 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Impact of COVID-19 and comorbidities on health and economics: Focus on developing countries and India. [Abstract]: BACKGROUND AND AIMS: Presence of comorbidities in patients with Coronavirus disease 2019 (COVID-19) have often been associated with increased in-hospital complications and mortality. Intriguingly,... |
32,990,448 | Asian Pac J Allergy Immunol | COVID-19 in children: Heterogeneity within the disease and hypothetical pathogenesis. | The disease course of coronavirus disease 2019 (COVID-19) is usually mild and self-limiting in previously healthy children, but they may also develop severe disease. Severe COVID-19 infection is especially observed in very young children or those with underlying comorbidities. Moreover, a multisystem inflammatory syndr... | Journal Article;Review | Suratannon, Narissara;Dik, Willem A;Chatchatee, Pantipa;Hagen, P Martin van | 10.12932/AP-170720-0920 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: COVID-19 in children: Heterogeneity within the disease and hypothetical pathogenesis. [Abstract]: The disease course of coronavirus disease 2019 (COVID-19) is usually mild and self-limiting in previously healthy children, but they may also develop severe disease. Severe COVID-19 infection is especially observe... | |
32,574,337 | Front Med (Lausanne) | Case Report: Clinical Treatment of the First Critical Patient With Coronavirus Disease (COVID-19) in Liaocheng, Shandong Province. | This paper reports the clinical characteristics, diagnosis, and treatment of the first critical COVID-19 patient in Liaocheng City, who was admitted to the intensive care unit isolation ward of Liaocheng People's Hospital on February 11, 2020. On admission, the patient had difficulty breathing, the oxygenation index wa... | covid-19;case report;clinical characteristics;clinical diagnosis and treatment;critical covid-19 patient;high-flow nasal cannula;plasma exchange | Case Reports | Tian, Hui;Sui, Yuanda;Tian, Suochen;Zou, Xiuli;Xu, Zhiping;He, Huang;Wu, Tiejun | 10.3389/fmed.2020.00249 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Case Report: Clinical Treatment of the First Critical Patient With Coronavirus Disease (COVID-19) in Liaocheng, Shandong Province. [Abstract]: This paper reports the clinical characteristics, diagnosis, and treatment of the first critical COVID-19 patient in Liaocheng City, who was admitted to the intensive ca... |
32,253,068 | J Autoimmun | Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy. | The Coronavirus-associated disease, that was first identified in 2019 in China (CoViD-19), is a pandemic caused by a bat-derived beta-coronavirus, named SARS-CoV2. It shares homology with SARS and MERS-CoV, responsible for past outbreaks in China and in Middle East. SARS-CoV2 spread from China where the first infection... | antimalarials;baricitinib;covid-19;rheumatic diseases;sars-cov2;tocilizumab | Journal Article;Review | Ceribelli, Angela;Motta, Francesca;De Santis, Maria;Ansari, Aftab A;Ridgway, William M;Gershwin, M Eric;Selmi, Carlo | 10.1016/j.jaut.2020.102442 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy. [Abstract]: The Coronavirus-associated disease, that was first identified in 2019 in China (CoViD-19), is a pandemic caused by a bat-derived beta-coronavirus, named SARS-CoV2. It shares homology with SARS and MERS-Co... |
32,550,096 | Cureus | COVID-19 Induced Hepatitis B Virus Reactivation: A Novel Case From the United Arab Emirates. | The novel coronavirus disease 2019 (COVID-19) clinically manifests as respiratory and gastrointestinal presentations, most commonly vomiting, diarrhea, and abdominal pain. Although the impaired liver function is prevalent in COVID-19, it is poorly understood. We report the first case of hepatitis B virus (HBV) reactiva... | acute on chronic liver disease;adult gastroenterology;covid 19;hepatitis virus;hepatology;liver function;novel coronavirus;uae;viral hepatitis b;viral infection | Case Reports | Aldhaleei, Wafa A;Alnuaimi, Abdulaziz;Bhagavathula, Akshaya S | 10.7759/cureus.8645 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: COVID-19 Induced Hepatitis B Virus Reactivation: A Novel Case From the United Arab Emirates. [Abstract]: The novel coronavirus disease 2019 (COVID-19) clinically manifests as respiratory and gastrointestinal presentations, most commonly vomiting, diarrhea, and abdominal pain. Although the impaired liver functi... |
32,685,700 | NPJ Digit Med | Germany's digital health reforms in the COVID-19 era: lessons and opportunities for other countries. | Reimbursement is a key challenge for many new digital health solutions, whose importance and value have been highlighted and expanded by the current COVID-19 pandemic. Germany's new Digital Healthcare Act (Digitale-Versorgung-Gesetz or DVG) entitles all individuals covered by statutory health insurance to reimbursement... | health policy;health services | Journal Article;Review | Gerke, Sara;Stern, Ariel D;Minssen, Timo | 10.1038/s41746-020-0306-7 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Germany's digital health reforms in the COVID-19 era: lessons and opportunities for other countries. [Abstract]: Reimbursement is a key challenge for many new digital health solutions, whose importance and value have been highlighted and expanded by the current COVID-19 pandemic. Germany's new Digital Healthca... |
33,050,860 | Curr Drug Targets | COVID-19 and Renal Diseases: An Update. | BACKGROUND: It becomes increasingly evident that the SARS-CoV-2 infection is not limited to the respiratory system. In addition to being a target of the virus, the kidney also seems to have substantial influence on the outcomes of the disease. <p> Methods: Data was obtained by a comprehensive and non-systematic search ... | covid-19;sars-cov-2;acute kidney injury;chronic kidney disease;renal dysfunction.;renal transplantation | Journal Article;Review | Cota, Leticia Bitencourt;Pedrosa, Ana Luisa;de Brito, Stephanie Bruna Camilo Soares;Froes, Ana Claudia Fontoura;de Carvalho, Sarah Tayna;Fonseca, Giulio Gori;Ferreira, Guilherme Costa;Fradico, Pollyanna Faria;Simoes E Silva, Ana Cristina | 10.2174/1389450121999201013151300 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: COVID-19 and Renal Diseases: An Update. [Abstract]: BACKGROUND: It becomes increasingly evident that the SARS-CoV-2 infection is not limited to the respiratory system. In addition to being a target of the virus, the kidney also seems to have substantial influence on the outcomes of the disease. <p> Methods: Da... |
32,507,570 | Am J Emerg Med | Acute myocarditis associated with COVID-19 infection. | We present the case of a 20-year-old male patient without previous history of cardiovascular disease who was admitted to our hospital with a new onset febrile sensation and chest pain. Chest computed tomography revealed a subpleural consolidation with a halo of ground-glass opacification. Blood tests revealed elevated ... | covid-19;mri;myocarditis | Case Reports;Video-Audio Media | Besler, Muhammed Said;Arslan, Halil | 10.1016/j.ajem.2020.05.100 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Acute myocarditis associated with COVID-19 infection. [Abstract]: We present the case of a 20-year-old male patient without previous history of cardiovascular disease who was admitted to our hospital with a new onset febrile sensation and chest pain. Chest computed tomography revealed a subpleural consolidatio... |
32,394,237 | J Thromb Thrombolysis | Sudden death due to acute pulmonary embolism in a young woman with COVID-19. | Coronavirus disease 2019 (COVID-19) is an infectious disease that primarily affects the respiratory system, but it may cause cardiovascular complications such as thromboembolism. Rarely, pulmonary embolism may be encountered in patients with severe COVID-19 infection, especially in intensive care units. An asymptomatic... | covid-19;case report;pulmonary embolism;sudden death | Case Reports;Journal Article | Polat, Veli;Bostanci, Gungor Ilayda | 10.1007/s11239-020-02132-5 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Sudden death due to acute pulmonary embolism in a young woman with COVID-19. [Abstract]: Coronavirus disease 2019 (COVID-19) is an infectious disease that primarily affects the respiratory system, but it may cause cardiovascular complications such as thromboembolism. Rarely, pulmonary embolism may be encounter... |
32,438,425 | Am J Perinatol | COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice. | OBJECTIVE: This study aimed to report a case series of pregnant women in New York City with confirmed or presumed coronavirus disease (COVID-19) infection. STUDY DESIGN: Beginning March 22, 2020, all pregnant women from one large obstetrical practice in New York City were contacted regularly to inquire about symptoms o... | Journal Article | Fox, Nathan S;Melka, Stephanie | 10.1055/s-0040-1712529 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice. [Abstract]: OBJECTIVE: This study aimed to report a case series of pregnant women in New York City with confirmed or presumed coronavirus disease (COVID-19) infection. STUDY DESIGN: Beginning March 22, 2020, all pregnant... | |
32,872,048 | Medicine (Baltimore) | Association between ABO blood groups and risk of coronavirus disease 2019: A protocol for systematic review and meta-analysis. | BACKGROUND: The 2019 Coronavirus Disease (COVID-19) pandemic has threatened millions of people worldwide. Growing evidence suggests that the ABO blood type contributed to the susceptibility of COVID-19, but the results are controversial. The major objective of this systematic review and meta-analysis study is to invest... | Journal Article | Liu, Nanyang;Zhang, Tingting;Ma, Lina;Wang, Huican;Li, Hao | 10.1097/MD.0000000000021709 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Association between ABO blood groups and risk of coronavirus disease 2019: A protocol for systematic review and meta-analysis. [Abstract]: BACKGROUND: The 2019 Coronavirus Disease (COVID-19) pandemic has threatened millions of people worldwide. Growing evidence suggests that the ABO blood type contributed to t... | |
32,349,051 | Obstet Gynecol | Early Acute Respiratory Support for Pregnant Patients With Coronavirus Disease 2019 (COVID-19) Infection. | The present coronavirus disease 2019 (COVID-19) pandemic is affecting pregnant patients worldwide. Although it appears that the severity of disease is reduced in pregnant patients, some are likely to develop severe disease. Our objective is to summarize the basic initial respiratory support interventions recommended fo... | Journal Article;Research Support, Non-U.S. Gov't | Pacheco, Luis D;Saad, Antonio F;Saade, George | 10.1097/AOG.0000000000003929 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Early Acute Respiratory Support for Pregnant Patients With Coronavirus Disease 2019 (COVID-19) Infection. [Abstract]: The present coronavirus disease 2019 (COVID-19) pandemic is affecting pregnant patients worldwide. Although it appears that the severity of disease is reduced in pregnant patients, some are lik... | |
32,578,792 | Rev Assoc Med Bras (1992) | What do we know about COVID-19? A review article. | OBJECTIVES: To bring summarized information about what has been published so far regarding Covid-19, facilitating the access to information and a better understanding of this pandemic, and to contribute to the medical community in the decision-making against this virus. METHODS: This review article brings collected inf... | Journal Article;Review | Vieira, Julia Maggi;Ricardo, Olivia Moura de Paula;Hannas, Carolina Miranda;Kanadani, Tereza Cristina Moreira;Prata, Tiago Dos Santos;Kanadani, Fabio Nishimura | 10.1590/1806-9282.66.4.534 | [
1,
1,
1,
0,
0,
0,
0
] | [Title]: What do we know about COVID-19? A review article. [Abstract]: OBJECTIVES: To bring summarized information about what has been published so far regarding Covid-19, facilitating the access to information and a better understanding of this pandemic, and to contribute to the medical community in the decision-makin... | |
32,768,699 | Int J Infect Dis | What can we learn from a COVID-19 lung biopsy? | We report the case of a patient diagnosed with severe pneumonia due to coronavirus disease 2019 (COVID-19). A percutaneous lung biopsy was performed under ultrasound guidance. Morphological and ultrastructural characteristics of the patient's lungs are presented, along with details of some important changes in inflamma... | covid-19;inflammatory biological markers;lung biopsy;morphological ultrastructure | Case Reports | Wu, Jinxiang;Yu, Jiguang;Zhou, Shengyu;Zhang, Jintao;Xu, Jiawei;Niu, Chuanzhen;Qu, Guimei;Han, Bo;Hu, Jing;Dong, Liang | 10.1016/j.ijid.2020.07.067 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: What can we learn from a COVID-19 lung biopsy? [Abstract]: We report the case of a patient diagnosed with severe pneumonia due to coronavirus disease 2019 (COVID-19). A percutaneous lung biopsy was performed under ultrasound guidance. Morphological and ultrastructural characteristics of the patient's lungs are... |
32,957,548 | J Clin Med | Complex Immunometabolic Profiling Reveals the Activation of Cellular Immunity and Biliary Lesions in Patients with Severe COVID-19. | This study aimed to assess the key laboratory features displayed by coronavirus disease 2019 (COVID-19) inpatients that are associated with mild, moderate, severe, and fatal courses of the disease, and through a longitudinal follow-up, to understand the dynamics of the COVID-19 pathophysiology. All severe acute respira... | covid-19;ggt;il-6;sars-cov-2;t cells;acute kidney injury;biliary lesion;hepatopathy;immunity;liver disease | Journal Article | Klocperk, Adam;Bloomfield, Marketa;Parackova, Zuzana;Zentsova, Irena;Vrabcova, Petra;Balko, Jan;Meseznikov, Grigorij;Casas Mendez, Luis Fernando;Grandcourtova, Alzbeta;Sipek, Jan;Tulach, Martin;Zamecnik, Josef;Vymazal, Tomas;Sediva, Anna | 10.3390/jcm9093000 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Complex Immunometabolic Profiling Reveals the Activation of Cellular Immunity and Biliary Lesions in Patients with Severe COVID-19. [Abstract]: This study aimed to assess the key laboratory features displayed by coronavirus disease 2019 (COVID-19) inpatients that are associated with mild, moderate, severe, and... |
32,490,726 | Med Leg J | Thromboinflammatory response in SARS-CoV-2 sepsis. | Viral sepsis is rare, and its real incidence is not known. SARS-CoV-2 infection causes the release of a significant amount of pro-inflammatory cytokines that aggravates interstitial pneumonia and evolves in viral sepsis with prominent hypercoagulability. We believe it is useful and advisable to establish early immunomo... | sars-cov-2;sepsis, covid-19, thrombosis, coagulopathy | Journal Article | Maiese, Aniello;Passaro, Giovanna;Matteis, Alessandra DE;Fazio, Valentina;Raffaele, La Russa;Paolo, Marco Di | 10.1177/0025817220926915 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Thromboinflammatory response in SARS-CoV-2 sepsis. [Abstract]: Viral sepsis is rare, and its real incidence is not known. SARS-CoV-2 infection causes the release of a significant amount of pro-inflammatory cytokines that aggravates interstitial pneumonia and evolves in viral sepsis with prominent hypercoagulab... |
32,925,138 | Work | Knowledge and practice regarding prevention of COVID-19 among the Saudi Arabian population. | BACKGROUND: Prevention is the best way to manage a pandemic like COVID-19. The World Health Organization has issued public advice to create awareness by providing people knowledge to prevent/protect them from COVID-19. Hence, the present study was planned to assess knowledge of prevention and its practical use amongst ... | awareness;covid-19;attitude;coronavirus;hygiene practice;infectious diseases;pandemic | Journal Article | Siddiqui, Ammar Ahmed;Alshammary, Freah;Amin, Junaid;Rathore, Hassaan Anwer;Hassan, Ibne;Ilyas, Muhammad;Alam, Mohammad Khursheed | 10.3233/WOR-203223 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Knowledge and practice regarding prevention of COVID-19 among the Saudi Arabian population. [Abstract]: BACKGROUND: Prevention is the best way to manage a pandemic like COVID-19. The World Health Organization has issued public advice to create awareness by providing people knowledge to prevent/protect them fro... |
32,496,256 | Indian J Public Health | Knowledge, attitude, and practices related to COVID-19 pandemic among social media users in J&K, India. | Background: A series of measures have been suggested to reduce Covid-19 infection, including knowledge training for prevention and control, isolation, disinfection, classified protections at different degrees in infection areas, and protection of confirmed cases. Objectives: We conducted this study with an aim to asses... | attitude;covid-19;ut of j and k;knowledge;practice | Journal Article | Dkhar, Sabira Aalia;Quansar, Ruqia;Saleem, Sheikh Mohd;Khan, S Muhammad Salim | 10.4103/ijph.IJPH_469_20 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Knowledge, attitude, and practices related to COVID-19 pandemic among social media users in J&K, India. [Abstract]: Background: A series of measures have been suggested to reduce Covid-19 infection, including knowledge training for prevention and control, isolation, disinfection, classified protections at diff... |
32,464,637 | Eur Heart J Cardiovasc Pharmacother | The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication: possible treatment options related to the renin-angiotensin system. | The SARS-CoV-2 pandemic is a healthcare crisis caused by insufficient knowledge applicable to effectively combat the virus. Therefore, different scientific discovery strategies need to be connected, to generate a rational treatment which can be made available as rapidly as possible. This relies on a solid theoretical u... | angiotensin receptor blockers;angiotensin-converting enzyme 2;covid-19;coronavirus;renin-angiotensin-aldosterone system | Journal Article;Review | Offringa, Annette;Montijn, Roy;Singh, Sandeep;Paul, Martin;Pinto, Yigal M;Pinto-Sietsma, Sara-Joan | 10.1093/ehjcvp/pvaa053 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication: possible treatment options related to the renin-angiotensin system. [Abstract]: The SARS-CoV-2 pandemic is a healthcare crisis caused by insufficient knowledge applicable to effectively combat the vi... |
32,925,701 | Pediatr Emerg Care | Lung Point-of-Care Ultrasound in Pediatric COVID-19: A Case Series. | Lung point-of-care ultrasound (POCUS) has been shown to be useful for identifying pulmonary pathology in adult patients with coronavirus disease 2019 (COVID-19). However, pediatric literature for POCUS in COVID-19 is limited. The objective of this case series was to describe lung POCUS findings in pediatric patients wi... | Case Reports;Journal Article;Review | Kennedy, Thomas M;Malia, Laurie;Dessie, Almaz;Kessler, David O;Ng, Lorraine;Chiang, Elaine L;Rabiner, Joni E | 10.1097/PEC.0000000000002254 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Lung Point-of-Care Ultrasound in Pediatric COVID-19: A Case Series. [Abstract]: Lung point-of-care ultrasound (POCUS) has been shown to be useful for identifying pulmonary pathology in adult patients with coronavirus disease 2019 (COVID-19). However, pediatric literature for POCUS in COVID-19 is limited. The o... | |
32,667,444 | Rev Bras Ter Intensiva | Guidelines for the pharmacological treatment of COVID-19. The task-force/consensus guideline of the Brazilian Association of Intensive Care Medicine, the Brazilian Society of Infectious Diseases and the Brazilian Society of Pulmonology and Tisiology. | INTRODUCTION: Different therapies are currently used, considered, or proposed for the treatment of COVID-19; for many of those therapies, no appropriate assessment of effectiveness and safety was performed. This document aims to provide scientifically available evidence-based information in a transparent interpretation... | Consensus Development Conference;Journal Article;Practice Guideline | Falavigna, Maicon;Colpani, Veronica;Stein, Cinara;Azevedo, Luciano Cesar Pontes;Bagattini, Angela Maria;Brito, Gabriela Vilela de;Chatkin, Jose Miguel;Cimerman, Sergio;Corradi, Mirian de Freitas Dal Ben;Cunha, Clovis Arns da;Medeiros, Flavia Cordeiro de;Oliveira Junior, Haliton Alves de;Fritscher, Leandro Genehr;Gazzan... | 10.5935/0103-507x.20200039 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Guidelines for the pharmacological treatment of COVID-19. The task-force/consensus guideline of the Brazilian Association of Intensive Care Medicine, the Brazilian Society of Infectious Diseases and the Brazilian Society of Pulmonology and Tisiology. [Abstract]: INTRODUCTION: Different therapies are currently ... | |
32,367,418 | Eur Radiol | Imaging features and evolution on CT in 100 COVID-19 pneumonia patients in Wuhan, China. | OBJECTIVES: To investigate CT images of 100 confirmed COVID-19 pneumonia patients to describe the lesion distribution, CT signs, and evolution during different courses. METHODS: A retrospective study of 100 COVID-19 pneumonia patients without ARDS was performed, and CT scans were reviewed. A COVID-19 pneumonia course d... | computed tomography;coronavirus;pneumonia | Journal Article | Zhou, Shuchang;Zhu, Tingting;Wang, Yujing;Xia, LiMing | 10.1007/s00330-020-06879-6 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Imaging features and evolution on CT in 100 COVID-19 pneumonia patients in Wuhan, China. [Abstract]: OBJECTIVES: To investigate CT images of 100 confirmed COVID-19 pneumonia patients to describe the lesion distribution, CT signs, and evolution during different courses. METHODS: A retrospective study of 100 COV... |
32,336,317 | BMB Rep | COVID-19: an update on diagnostic and therapeutic approaches. | The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 has created havoc, and scientists and physicians are urged to test the efficiency and safety of drugs used to treat this disease. In such a pandemic situation, various steps have been taken ... | News | Iyer, Mahalaxmi;Jayaramayya, Kaavya;Subramaniam, Mohana Devi;Lee, Soo Bin;Dayem, Ahmed Abdal;Cho, Ssang-Goo;Vellingiri, Balachandar | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19: an update on diagnostic and therapeutic approaches. [Abstract]: The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 has created havoc, and scientists and physicians are urged to test the efficiency and safety of drugs used ... | ||
32,416,259 | Virus Res | On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2. | A new betacoronavirus named SARS-CoV-2 has emerged as a new threat to global health and economy. A promising target for both diagnosis and therapeutics treatments of the new disease named COVID-19 is the coronavirus (CoV) spike (S) glycoprotein. By constant-pH Monte Carlo simulations and the PROCEEDpKa method, we have ... | ace2;antibody development;antigenic analysis;binding affinity;computer simulation;coronavirus;electrostatic interactions;epitopes;host-pathogen interaction;protein-protein interaction;sars-cov-2;ph effect | Journal Article;Research Support, Non-U.S. Gov't | Correa Giron, Carolina;Laaksonen, Aatto;Barroso da Silva, Fernando L | 10.1016/j.virusres.2020.198021 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2. [Abstract]: A new betacoronavirus named SARS-CoV-2 has emerged as a new threat to global health and economy. A promising target for both diagnosis and therapeutics tr... |
32,778,962 | Pharm Res | Repurposing of Kinase Inhibitors for Treatment of COVID-19. | The outbreak of COVID-19, the pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spurred an intense search for treatments by the scientific community. In the absence of a vaccine, the goal is to target the viral life cycle and alleviate the lung-damaging symptoms of infecti... | covid-19;coronavirus;mers-cov;sars-cov;sars-cov-2;antiviral therapy;kinase inhibitors;pharmacokinetics | Journal Article;Review | Weisberg, Ellen;Parent, Alexander;Yang, Priscilla L;Sattler, Martin;Liu, Qingsong;Liu, Qingwang;Wang, Jinhua;Meng, Chengcheng;Buhrlage, Sara J;Gray, Nathanael;Griffin, James D | 10.1007/s11095-020-02851-7 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Repurposing of Kinase Inhibitors for Treatment of COVID-19. [Abstract]: The outbreak of COVID-19, the pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spurred an intense search for treatments by the scientific community. In the absence of a vaccine, the goal is t... |
32,542,337 | Eur Heart J Cardiovasc Pharmacother | A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. | INTRODUCTION: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) share their target receptor site with the SARS-CoV-2 virus, that may cause ACE2 receptor up-regulation which raised concerns regarding ACEI and ARB use in COVID-19 patients. However, many medical professional societi... | mortality;angiotensin receptor blocker;angiotensin-converting enzyme inhibitor;covid-19;clinical severity;meta-analysis | Journal Article;Meta-Analysis;Systematic Review | Grover, Abhinav;Oberoi, Mansi | 10.1093/ehjcvp/pvaa064 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. [Abstract]: INTRODUCTION: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) share their target recep... |
33,063,236 | Intern Emerg Med | Request of hospital care dropped for TIA but remained stable for stroke during COVID-19 pandemic at a large Italian university hospital. | Reduced incidence of stroke during COVID-19 pandemic was sometimes reported. While decrease in stroke incidence and fear of patients to go to the hospitals were sometimes invoked to explain this decrease, reduction in urban pollution was also hypothesized as a possible cause. We investigated statistically the incidence... | covid-19;hemorrhagic stroke;hospital care;ischemic stroke;stroke;transient ischemic attack | Journal Article | Balestrino, Maurizio;Coccia, Alberto;Boffa, Alessandra Silvia;Furgani, Andrea;Bermano, Francesco;Finocchi, Cinzia;Bandettini di Poggio, Monica Laura;Malfatto, Laura;Farinini, Daniele;Schenone, Angelo | 10.1007/s11739-020-02522-w | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Request of hospital care dropped for TIA but remained stable for stroke during COVID-19 pandemic at a large Italian university hospital. [Abstract]: Reduced incidence of stroke during COVID-19 pandemic was sometimes reported. While decrease in stroke incidence and fear of patients to go to the hospitals were s... |
32,987,183 | Int J Infect Dis | Facemask use in community settings to prevent respiratory infection transmission: a rapid review and meta-analysis. | INTRODUCTION: Synthesis of the available evidence on the effectiveness of medical and cloth facemask use by the general public in community settings is required to learn lessons for future respiratory epidemics/pandemics. METHOD: We utilized search terms relating to facemasks, infection, and community settings on PubMe... | facemask;community setting;household | Journal Article;Review | Chaabna, Karima;Doraiswamy, Sathyanarayanan;Mamtani, Ravinder;Cheema, Sohaila | 10.1016/j.ijid.2020.09.1434 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Facemask use in community settings to prevent respiratory infection transmission: a rapid review and meta-analysis. [Abstract]: INTRODUCTION: Synthesis of the available evidence on the effectiveness of medical and cloth facemask use by the general public in community settings is required to learn lessons for f... |
32,903,849 | Front Med (Lausanne) | Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis. | Background: COVID-19 is a serious and potentially deadly disease. Early diagnosis of infected individuals will play an important role in stopping its further escalation. The present gold standard for sampling is the nasopharyngeal swab method. However, several recent papers suggested that saliva-based testing is a prom... | covid-19;sars-cov-2;coronavirus;diagnostic tests;meta-analysis;saliva;systematic review | Systematic Review | Czumbel, Laszlo Mark;Kiss, Szabolcs;Farkas, Nelli;Mandel, Ivan;Hegyi, Anita;Nagy, Akos;Lohinai, Zsolt;Szakacs, Zsolt;Hegyi, Peter;Steward, Martin C;Varga, Gabor | 10.3389/fmed.2020.00465 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis. [Abstract]: Background: COVID-19 is a serious and potentially deadly disease. Early diagnosis of infected individuals will play an important role in stopping its further escalation. The present gold standard for sampling is the nasopharyng... |
32,489,176 | Euro Surveill | Rapid response infrastructure for pandemic preparedness in a tertiary care hospital: lessons learned from the COVID-19 outbreak in Cologne, Germany, February to March 2020. | The coronavirus disease (COVID-19) pandemic has caused tremendous pressure on hospital infrastructures such as emergency rooms (ER) and outpatient departments. To avoid malfunctioning of critical services because of large numbers of potentially infected patients seeking consultation, we established a COVID-19 rapid res... | covid-19;sars-cov-2;outbreak;pandemic preparedness;risk assessment | Journal Article;Research Support, Non-U.S. Gov't | Augustin, Max;Schommers, Philipp;Suarez, Isabelle;Koehler, Philipp;Gruell, Henning;Klein, Florian;Maurer, Christian;Langerbeins, Petra;Priesner, Vanessa;Schmidt-Hellerau, Kirsten;Malin, Jakob J;Stecher, Melanie;Jung, Norma;Wiesmuller, Gerhard;Meissner, Arne;Zweigner, Janine;Langebartels, Georg;Kolibay, Felix;Suarez, Vi... | 10.2807/1560-7917.ES.2020.25.21.2000531 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Rapid response infrastructure for pandemic preparedness in a tertiary care hospital: lessons learned from the COVID-19 outbreak in Cologne, Germany, February to March 2020. [Abstract]: The coronavirus disease (COVID-19) pandemic has caused tremendous pressure on hospital infrastructures such as emergency rooms... |
32,542,058 | Biol Conserv | Guidelines for communicating about bats to prevent persecution in the time of COVID-19. | While the current COVID-19 pandemic continues to wreak havoc on human health and national economies, conservationists are struggling to prevent misguided persecution of bats, which are misleadingly being blamed for spreading the disease. Although at a global level, such persecution is relatively uncommon, even a few mi... | behavioural change;conservation communication;conservation psychology;human-wildlife conflict;message framing;zoonoses | Journal Article;Review | MacFarlane, Douglas;Rocha, Ricardo | 10.1016/j.biocon.2020.108650 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Guidelines for communicating about bats to prevent persecution in the time of COVID-19. [Abstract]: While the current COVID-19 pandemic continues to wreak havoc on human health and national economies, conservationists are struggling to prevent misguided persecution of bats, which are misleadingly being blamed ... |
33,068,863 | Int Immunopharmacol | Nucleic acid and antibody assay results in Chinese patients with coronavirus disease 2019 (COVID-19). | AIM: To evaluate the nucleic acid and antibody test results of patients with Coronavirus Disease 2019 (COVID-19) in China. METHODS: All patients with laboratory-confirmed SARS-CoV-2 infection from Jan to Apr 2020were retrospectively analyzed. Clinical characteristics and laboratory test results were obtained from elect... | antibody;coronavirus disease 2019 (covid-19);nucleic acids;re-positivepatients | Journal Article | Lu, Yong;Li, Yongyan;Wang, Yiping;Luo, Jianping;Yu, Wanjun | 10.1016/j.intimp.2020.107089 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Nucleic acid and antibody assay results in Chinese patients with coronavirus disease 2019 (COVID-19). [Abstract]: AIM: To evaluate the nucleic acid and antibody test results of patients with Coronavirus Disease 2019 (COVID-19) in China. METHODS: All patients with laboratory-confirmed SARS-CoV-2 infection from ... |
32,505,908 | J Neuroimmunol | Immunologic characterization of a immunosuppressed multiple sclerosis patient that recovered from SARS-CoV-2 infection. | A multiple sclerosis patient infected by SARS-CoV-2 during fingolimod therapy was hospitalized with moderate clinical features, and recovered in 15 days. High levels of CCL5 and CCL10 chemokines and of antibody-secreting B cells were detected, while the levels other B- and T-cell subsets were comparable to that of appr... | covid-19;fingolimod;multiple sclerosis | Case Reports;Journal Article;Research Support, Non-U.S. Gov't | Chiarini, Marco;Paghera, Simone;Moratto, Daniele;Rossi, Nicola De;Giacomelli, Mauro;Badolato, Raffaele;Capra, Ruggero;Imberti, Luisa | 10.1016/j.jneuroim.2020.577282 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Immunologic characterization of a immunosuppressed multiple sclerosis patient that recovered from SARS-CoV-2 infection. [Abstract]: A multiple sclerosis patient infected by SARS-CoV-2 during fingolimod therapy was hospitalized with moderate clinical features, and recovered in 15 days. High levels of CCL5 and C... |
32,417,709 | Diabetes Metab Syndr | Mechanism of inflammatory response in associated comorbidities in COVID-19. | BACKGROUND AND AIMS: The outbreak of the new coronavirus, SARS-CoV-2, causes a respiratory disease and individuals with pre-existing cardiometabolic disorders display worse prognosis through the infection course. The aim of this minireview is to present epidemiological data related to metabolic comorbidities in associa... | diabetes mellitus;hypertension arterial;immune response;obesity;vitamin d | Journal Article;Review | de Lucena, Thays Maria Costa;da Silva Santos, Ariane Fernandes;de Lima, Brenda Regina;de Albuquerque Borborema, Maria Eduarda;de Azevedo Silva, Jaqueline | 10.1016/j.dsx.2020.05.025 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Mechanism of inflammatory response in associated comorbidities in COVID-19. [Abstract]: BACKGROUND AND AIMS: The outbreak of the new coronavirus, SARS-CoV-2, causes a respiratory disease and individuals with pre-existing cardiometabolic disorders display worse prognosis through the infection course. The aim of... |
33,073,676 | Virulence | Reliability of induced sputum test is greater than that of throat swab test for detecting SARS-CoV-2 in patients with COVID-19: A multi-center cross-sectional study. | We previously reported that sputum induction was more sensitive than throat swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in two convalescent coronavirus disease 2019 (COVID-19) patients; however, the value and safety of induced sputum testing require further study. We conducte... | covid-19;sars-cov-2;induced sputum;reliability;throat swab | Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't | Lai, Tianwen;Xiang, Fangfei;Zeng, Jianfeng;Huang, Yingzi;Jia, Liping;Chen, Hui;Wu, Jiayuan;Xie, Jianfeng;Liu, Shuna;Deng, Wei;Zheng, Weiqiang;Huang, Yang;Zhang, Qinfu;Luo, Qingfeng;Mo, Fan;Long, Lieming;Zhang, Wuying;Chen, Wenna;Han, Huanqin | 10.1080/21505594.2020.1831342 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Reliability of induced sputum test is greater than that of throat swab test for detecting SARS-CoV-2 in patients with COVID-19: A multi-center cross-sectional study. [Abstract]: We previously reported that sputum induction was more sensitive than throat swabs for the detection of severe acute respiratory syndr... |
32,674,173 | Orthopedics | The Early Effect of COVID-19 Restrictions on an Academic Orthopedic Surgery Department. | The SARS-CoV-2 (COVID-19) pandemic has had a global influence on health care. The authors examined the early effect of hospital- and state-mandated restrictions on an orthopedic surgery department and hypothesized that the volume of ambulatory clinic encounters, office and surgical procedures, and cases would dramatica... | Journal Article | Earp, Brandon E;Zhang, Dafang;Benavent, Kyra A;Byrne, Laura;Blazar, Philip E | 10.3928/01477447-20200624-03 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The Early Effect of COVID-19 Restrictions on an Academic Orthopedic Surgery Department. [Abstract]: The SARS-CoV-2 (COVID-19) pandemic has had a global influence on health care. The authors examined the early effect of hospital- and state-mandated restrictions on an orthopedic surgery department and hypothesiz... | |
32,801,972 | Risk Manag Healthc Policy | Prevention and Treatment Strategies for the Cardiology Department of a Non-COVID-19 Designated Hospital in the Post-Epidemic Period. | Background: Coronavirus infection disease 2019 (COVID-19) occurred in Wuhan in December 2019. With the spread of the virus, the global epidemic situation has become extremely serious, especially in the United States, Spain and Italy. Due to a series of control measures, the epidemic situation in Wuhan has been alleviat... | non-covid-19 designated hospitals;post-epidemic period;strategy | Journal Article | Fan, Qian;Chen, Xin;Lin, Yan;Wang, Zhiquan | 10.2147/RMHP.S261533 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Prevention and Treatment Strategies for the Cardiology Department of a Non-COVID-19 Designated Hospital in the Post-Epidemic Period. [Abstract]: Background: Coronavirus infection disease 2019 (COVID-19) occurred in Wuhan in December 2019. With the spread of the virus, the global epidemic situation has become e... |
32,659,945 | Brain Sci | Effective Strategies for Managing COVID-19 Emergency Restrictions for Adults with Severe ASD in a Daycare Center in Italy. | The COVID-19 pandemic has posed a serious challenge for the life and mental health of people with autism spectrum disorder (ASD). COVID-19 sanitary restrictions led to significant changes in the lives of people with ASD, including their routines; similarly, these modifications affected the daily activities of the dayca... | covid-19;autism spectrum disorder;challenging behavior | Journal Article | Brondino, Natascia;Damiani, Stefano;Politi, Pierluigi | 10.3390/brainsci10070436 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Effective Strategies for Managing COVID-19 Emergency Restrictions for Adults with Severe ASD in a Daycare Center in Italy. [Abstract]: The COVID-19 pandemic has posed a serious challenge for the life and mental health of people with autism spectrum disorder (ASD). COVID-19 sanitary restrictions led to signific... |
32,804,682 | Am J Ther | Vitamin D Supplementation in COVID-19 Patients: A Clinical Case Series. | BACKGROUND: Coronavirus disease 2019 (COVID-19) has infected more than 4.4 million people and caused more than 300,000 deaths partly through acute respiratory distress syndrome with propensity to affect African American and Hispanic communities disproportionately. Patients with worse outcomes have exhibited higher bloo... | Journal Article | Ohaegbulam, Kim C;Swalih, Mohamed;Patel, Pranavkumar;Smith, Miriam A;Perrin, Richard | 10.1097/MJT.0000000000001222 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Vitamin D Supplementation in COVID-19 Patients: A Clinical Case Series. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has infected more than 4.4 million people and caused more than 300,000 deaths partly through acute respiratory distress syndrome with propensity to affect African American and His... | |
33,001,869 | MMWR Morb Mortal Wkly Rep | COVID-19 Trends Among School-Aged Children - United States, March 1-September 19, 2020. | Approximately 56 million school-aged children (aged 5-17 years) resumed education in the United States in fall 2020.* Analysis of demographic characteristics, underlying conditions, clinical outcomes, and trends in weekly coronavirus disease 2019 (COVID-19) incidence during March 1-September 19, 2020 among 277,285 labo... | Journal Article | Leeb, Rebecca T;Price, Sandy;Sliwa, Sarah;Kimball, Anne;Szucs, Leigh;Caruso, Elise;Godfred-Cato, Shana;Lozier, Matthew | 10.15585/mmwr.mm6939e2 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 Trends Among School-Aged Children - United States, March 1-September 19, 2020. [Abstract]: Approximately 56 million school-aged children (aged 5-17 years) resumed education in the United States in fall 2020.* Analysis of demographic characteristics, underlying conditions, clinical outcomes, and trends... | |
32,378,471 | Emerg Microbes Infect | Animal models for emerging coronavirus: progress and new insights. | The emergences of coronaviruses have caused a serious global public health problem because their infection in humans caused the severe acute respiratory disease and deaths. The outbreaks of lethal coronaviruses have taken place for three times within recent two decades (SARS-CoV in 2002, MERS-CoV in 2012 and SARS-CoV-2... | coronavirus;animal model;infectious disease;respiratory syndrome;vaccine and drug discovery | Journal Article;Review | Yuan, Lunzhi;Tang, Qiyi;Cheng, Tong;Xia, Ningshao | 10.1080/22221751.2020.1764871 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Animal models for emerging coronavirus: progress and new insights. [Abstract]: The emergences of coronaviruses have caused a serious global public health problem because their infection in humans caused the severe acute respiratory disease and deaths. The outbreaks of lethal coronaviruses have taken place for ... |
32,407,609 | Ann Clin Transl Neurol | De Novo Status Epilepticus in patients with COVID-19. | Neurological complications are increasingly recognized with SARS-CoV-2, the causative pathogen for COVID-19. We present a single-center retrospective case series reporting the EEG and outcome of de novo status epilepticus (SE) in two African-American women with laboratory-confirmed SARS-CoV-2 virus. SE was the initial ... | Case Reports;Journal Article | Somani, Sana;Pati, Sandipan;Gaston, Tyler;Chitlangia, Alissa;Agnihotri, Shruti | 10.1002/acn3.51071 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: De Novo Status Epilepticus in patients with COVID-19. [Abstract]: Neurological complications are increasingly recognized with SARS-CoV-2, the causative pathogen for COVID-19. We present a single-center retrospective case series reporting the EEG and outcome of de novo status epilepticus (SE) in two African-Ame... | |
32,768,020 | Indian Heart J | Will the hidden specter of acute coronary syndrome (ACS) and ST-segment elevation myocardial infarction (STEMI) emerge from the avalanche of COVID-19? | There has been a huge impact of the COVID-19 pandemic on global healthcare systems. Advisories across the world have appealed to people to stay at home and observe social distancing to slow down the pandemic. However it is important to realize as to how this is affecting acute cardiovascular care. Recent studies from E... | acute coronary syndrome;covid-19 pandemic;patient care | Journal Article | Kapoor, Aditya;Yadav, Rakesh | 10.1016/j.ihj.2020.05.017 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Will the hidden specter of acute coronary syndrome (ACS) and ST-segment elevation myocardial infarction (STEMI) emerge from the avalanche of COVID-19? [Abstract]: There has been a huge impact of the COVID-19 pandemic on global healthcare systems. Advisories across the world have appealed to people to stay at h... |
32,963,028 | BMJ Open Respir Res | SARS-CoV-2 organising pneumonia: 'Has there been a widespread failure to identify and treat this prevalent condition in COVID-19?' | Reviews of COVID-19 CT imaging along with postmortem lung biopsies and autopsies indicate that the majority of patients with COVID-19 pulmonary involvement have secondary organising pneumonia (OP) or its histological variant, acute fibrinous and organising pneumonia, both well-known complications of viral infections. F... | imaging/ct mri etc;pneumonia;rare lung diseases;viral infection | Journal Article;Review | Kory, Pierre;Kanne, Jeffrey P | 10.1136/bmjresp-2020-000724 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: SARS-CoV-2 organising pneumonia: 'Has there been a widespread failure to identify and treat this prevalent condition in COVID-19?' [Abstract]: Reviews of COVID-19 CT imaging along with postmortem lung biopsies and autopsies indicate that the majority of patients with COVID-19 pulmonary involvement have seconda... |
32,444,876 | J Infect Dis | Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice. | We simulated 3 transmission modes, including close-contact, respiratory droplets and aerosol routes, in the laboratory. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be highly transmitted among naive human angiotensin-converting enzyme 2 (hACE2) mice via close contact because 7 of 13 naive hACE2 mice... | sars-cov-2;aerosol;close contact;hace2 transgenic mice;respiratory droplets;transmission routes | Journal Article;Research Support, Non-U.S. Gov't | Bao, Linlin;Gao, Hong;Deng, Wei;Lv, Qi;Yu, Haisheng;Liu, Mingya;Yu, Pin;Liu, Jiangning;Qu, Yajin;Gong, Shuran;Lin, Kaili;Qi, Feifei;Xu, Yanfeng;Li, Fengli;Xiao, Chong;Xue, Jing;Song, Zhiqi;Xiang, Zhiguang;Wang, Guanpeng;Wang, Shunyi;Liu, Xing;Zhao, Wenjie;Han, Yunlin;Wei, Qiang;Qin, Chuan | 10.1093/infdis/jiaa281 | [
0,
0,
0,
0,
1,
0,
0
] | [Title]: Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice. [Abstract]: We simulated 3 transmission modes, including close-contact, respiratory droplets and aerosol routes, in the laboratory. Severe acute respirato... |
32,960,908 | PLoS One | The efficiency in the ordinary hospital bed management in Italy: An in-depth analysis of intensive care unit in the areas affected by COVID-19 before the outbreak. | Since the end of February 2020 a severe diffusion of COVID-19 has affected Italy and in particular its northern regions, resulting in a high demand of hospitalizations in particular in the intensive care units (ICUs). Hospitals are suffering the high degree of patients to be treated for respiratory diseases and the maj... | Journal Article | Pecoraro, Fabrizio;Clemente, Fabrizio;Luzi, Daniela | 10.1371/journal.pone.0239249 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The efficiency in the ordinary hospital bed management in Italy: An in-depth analysis of intensive care unit in the areas affected by COVID-19 before the outbreak. [Abstract]: Since the end of February 2020 a severe diffusion of COVID-19 has affected Italy and in particular its northern regions, resulting in a... | |
32,461,141 | Kidney Int | The case of complement activation in COVID-19 multiorgan impact. | The novel coronavirus disease COVID-19 originates in the lungs, but it may extend to other organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute kidney injury. In severe cases, the presence of kidney injury is associated with increased risk of death, highlighting the relevance of this ... | c5 inhibition;covid-19;complement activation;complement terminal pathway;kidney injury;vascular injury | Journal Article;Research Support, Non-U.S. Gov't;Review | Noris, Marina;Benigni, Ariela;Remuzzi, Giuseppe | 10.1016/j.kint.2020.05.013 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The case of complement activation in COVID-19 multiorgan impact. [Abstract]: The novel coronavirus disease COVID-19 originates in the lungs, but it may extend to other organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute kidney injury. In severe cases, the presence of kidney ... |
32,291,968 | Thorac Cancer | Recommendations of individualized medical treatment and common adverse events management for lung cancer patients during the outbreak of COVID-19 epidemic. | Since its outbreak in December 2019 in China, the novel coronavirus disease (COVID-19) has rapidly spread and affected several countries. It has resulted in a difficult situation for cancer patients owing to the risks of the epidemic situation outbreak as well as cancer. Patients with cancer are more likely than the ge... | covid-19;lung neoplasms;therapeutics | Journal Article;Research Support, Non-U.S. Gov't | Zhao, Zhe;Bai, Hua;Duan, Jianchun;Wang, Jie | 10.1111/1759-7714.13424 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Recommendations of individualized medical treatment and common adverse events management for lung cancer patients during the outbreak of COVID-19 epidemic. [Abstract]: Since its outbreak in December 2019 in China, the novel coronavirus disease (COVID-19) has rapidly spread and affected several countries. It ha... |
32,330,531 | Urology | Managing Urology Consultations During COVID-19 Pandemic: Application of a Structured Care Pathway. | OBJECTIVE: To describe and evaluate a risk-stratified triage pathway for inpatient urology consultations during the SARS-CoV-2 (COVID-19) pandemic. This pathway seeks to outline a urology patient care strategy that reduces the transmission risk to both healthcare providers and patients, reduces the healthcare burden, a... | Journal Article | Borchert, Alex;Baumgarten, Lee;Dalela, Deepansh;Jamil, Marcus;Budzyn, Jeffrey;Kovacevic, Natalija;Yaguchi, Grace;Palma-Zamora, Isaac;Perkins, Sara;Bazzi, Mahdi;Wong, Phil;Sood, Akshay;Peabody, James;Rogers, Craig G;Dabaja, Ali;Atiemo, Humphrey | 10.1016/j.urology.2020.04.059 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Managing Urology Consultations During COVID-19 Pandemic: Application of a Structured Care Pathway. [Abstract]: OBJECTIVE: To describe and evaluate a risk-stratified triage pathway for inpatient urology consultations during the SARS-CoV-2 (COVID-19) pandemic. This pathway seeks to outline a urology patient care... | |
32,967,466 | Eur J Ophthalmol | Early impact of COVID-19 outbreak on eye care: Insights from EUROCOVCAT group. | The recent outbreak of coronavirus disease 2019 (COVID-19) has been declared a public health emergency worldwide. The scientific community has put in much effort and published studies that described COVID-19's biology, transmission, clinical diagnosis, candidate therapeutics, and vaccines. However, to date, only a few ... | covid-19 pandemic;cataract surgery;cornea transplantation;glaucoma;intravitreal injection;irreversible blindness;ophthalmology;retinal detachment surgery | Editorial | Toro, Mario Damiano;Brezin, Antoine Pierre;Burdon, Michael;Cummings, Arthur Bernard;Evren Kemer, Ozlem;Malyugin, Boris Edvard;Prieto, Isabel;Teus, Miguel Angel;Tognetto, Daniele;Tornblom, Riikka;Posarelli, Chiara;Choragiewicz, Tomasz;Rejdak, Robert | 10.1177/1120672120960339 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Early impact of COVID-19 outbreak on eye care: Insights from EUROCOVCAT group. [Abstract]: The recent outbreak of coronavirus disease 2019 (COVID-19) has been declared a public health emergency worldwide. The scientific community has put in much effort and published studies that described COVID-19's biology, t... |
33,068,588 | Eur J Pharmacol | Perspectives on mechanistic implications of ROS inducers for targeting viral infections. | In this perspective, we propose to leverage reactive oxygen species (ROS) induction as a potential therapeutic measure against viral infections. Our rationale for targeting RNA viral infections by pro-oxidants is routed on the mechanistic hypothesis that ROS based treatment paradigm could impair RNA integrity faster th... | covid-19;plumbagin;rna degradation;ros inducers;sars-cov-2 | Journal Article | Nadhan, Revathy;Patra, Dipyaman;Krishnan, Neethu;Rajan, Arathi;Gopala, Srinivas;Ravi, Dashnamoorthy;Srinivas, Priya | 10.1016/j.ejphar.2020.173621 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Perspectives on mechanistic implications of ROS inducers for targeting viral infections. [Abstract]: In this perspective, we propose to leverage reactive oxygen species (ROS) induction as a potential therapeutic measure against viral infections. Our rationale for targeting RNA viral infections by pro-oxidants ... |
32,708,922 | Healthcare (Basel) | Cancer in the Time of Coronavirus: A Call for Crisis Oncology Standards of Care. | Since the Coronavirus Disease 2019 (COVID-19) was identified as a global pandemic, health systems have been severely strained, particularly affecting vulnerable populations such as patients with cancer. In response to the COVID-19 pandemic, a variety of oncology specialty societies are making recommendations for standa... | covid-19;coronavirus;cancer;crisis;disaster preparedness | Journal Article | Kelkar, Amar H;Cogle, Christopher R | 10.3390/healthcare8030214 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Cancer in the Time of Coronavirus: A Call for Crisis Oncology Standards of Care. [Abstract]: Since the Coronavirus Disease 2019 (COVID-19) was identified as a global pandemic, health systems have been severely strained, particularly affecting vulnerable populations such as patients with cancer. In response to ... |
32,307,245 | J Microbiol Immunol Infect | Treatment options for COVID-19: The reality and challenges. | An outbreak related to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China in December 2019. An extremely high potential for dissemination resulted in the global coronavirus disease 2019 (COVID-19) pandemic in 2020. Despite the worsening trends of COVID-19, no drugs are v... | angiotensin converting enzyme inhibitors;coronavirus disease 2019 (covid-19);hydroxychloroquine;non-steroidal anti-inflammatory drugs;remdesivir;severe acute respiratory syndrome coronavirus 2 (sars-cov-2) | Journal Article;Review | Jean, Shio-Shin;Lee, Ping-Ing;Hsueh, Po-Ren | 10.1016/j.jmii.2020.03.034 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Treatment options for COVID-19: The reality and challenges. [Abstract]: An outbreak related to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China in December 2019. An extremely high potential for dissemination resulted in the global coronavirus disease 2019 (COV... |
32,292,843 | Adv Radiat Oncol | Southern Italy: How the Availability of Radiation Therapy, Patient Outcomes, and Risk to Health Care Providers Have Changed During the Coronavirus Disease 2019 Pandemic. | The first actions and provisions in a Southern Italy Department of Radiation Oncology are described at the inception of the COVID-19 pandemic. | Journal Article | Portaluri, Maurizio;Tramacere, Francesco;Portaluri, Tommaso;Gianicolo, Emilio A L | 10.1016/j.adro.2020.03.016 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Southern Italy: How the Availability of Radiation Therapy, Patient Outcomes, and Risk to Health Care Providers Have Changed During the Coronavirus Disease 2019 Pandemic. [Abstract]: The first actions and provisions in a Southern Italy Department of Radiation Oncology are described at the inception of the COVID... | |
32,339,350 | Mycoses | COVID-19 associated pulmonary aspergillosis. | OBJECTIVES: Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany. METHODS: A retrospective chart ... | aspergillus;ecmo;icu;sars-cov-2;isavuconazole;voriconazole | Case Reports;Journal Article | Koehler, Philipp;Cornely, Oliver A;Bottiger, Bernd W;Dusse, Fabian;Eichenauer, Dennis A;Fuchs, Frieder;Hallek, Michael;Jung, Norma;Klein, Florian;Persigehl, Thorsten;Rybniker, Jan;Kochanek, Matthias;Boll, Boris;Shimabukuro-Vornhagen, Alexander | 10.1111/myc.13096 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: COVID-19 associated pulmonary aspergillosis. [Abstract]: OBJECTIVES: Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a ... |
32,292,817 | One Health | Coalition: Advocacy for prospective clinical trials to test the post-exposure potential of hydroxychloroquine against COVID-19. | Our coalition of public health experts, doctors, and scientists worldwide want to draw attention to the need for high-quality evaluation protocols of the potential beneficial effect of hydroxychloroquine (HCQ) as a post-exposure drug for exposed people. In the absence of an approved, recognized effective pre or post-ex... | covid19;chloroquine;coronavirus, malaria, antiviral;hydroxychloroquine;immunomodulation;sars-cov2;systemic lupus erythematosus | Editorial | Picot, Stephane;Marty, Aileen;Bienvenu, Anne-Lise;Blumberg, Lucille H;Dupouy-Camet, Jean;Carnevale, Pierre;Kano, Shigeyuki;Jones, Malcolm K;Daniel-Ribeiro, Claudio Tadeu;Mas-Coma, Santiago | 10.1016/j.onehlt.2020.100131 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Coalition: Advocacy for prospective clinical trials to test the post-exposure potential of hydroxychloroquine against COVID-19. [Abstract]: Our coalition of public health experts, doctors, and scientists worldwide want to draw attention to the need for high-quality evaluation protocols of the potential benefic... |
32,516,750 | JMIR Mhealth Uhealth | Using eHealth to Support COVID-19 Education, Self-Assessment, and Symptom Monitoring in the Netherlands: Observational Study. | BACKGROUND: The coronavirus disease (COVID-19) situation demands a lot from citizens, health care providers, and governmental institutions. Citizens need to cope with guidelines on social interaction, work, home isolation, and symptom recognition. Additionally, health care providers and policy makers have to cope with ... | covid-19;ehealth;mhealth;mobile phone;patient education;self-management;smartphone | Journal Article;Observational Study | Timmers, Thomas;Janssen, Loes;Stohr, Joep;Murk, J L;Berrevoets, M A H | 10.2196/19822 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Using eHealth to Support COVID-19 Education, Self-Assessment, and Symptom Monitoring in the Netherlands: Observational Study. [Abstract]: BACKGROUND: The coronavirus disease (COVID-19) situation demands a lot from citizens, health care providers, and governmental institutions. Citizens need to cope with guidel... |
32,745,466 | Hematol Oncol Stem Cell Ther | The risk and prognosis of COVID-19 infection in cancer patients: A systematic review and meta-analysis. | Numerous studies have been published regarding outcomes of cancer patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causing the coronavirus disease 2019 (COVID-19) infection. However, most of these are single-center studies with a limited number of patients. To better assess ... | covid-19;cancer;mechanical ventilation;meta-analysis;mortality | Journal Article | ElGohary, Ghada M;Hashmi, Shahrukh;Styczynski, Jan;Kharfan-Dabaja, Mohamed A;Alblooshi, Rehab M;de la Camara, Rafael;Mohmed, Sherif;Alshaibani, Alfadel;Cesaro, Simone;Abd El-Aziz, Nashwa;Almaghrabi, Reem;Gergis, Usama;Majhail, Navneet S;El-Gohary, Yasser;Chemaly, Roy F;Aljurf, Mahmoud;El Fakih, Riad | 10.1016/j.hemonc.2020.07.005 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: The risk and prognosis of COVID-19 infection in cancer patients: A systematic review and meta-analysis. [Abstract]: Numerous studies have been published regarding outcomes of cancer patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causing the coronavirus disease 201... |
32,738,466 | Am J Emerg Med | Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. | Coronavirus disease 2019 (COVID-19) infection has now reached a pandemic state, affecting more than a million patients worldwide. Predictors of disease outcomes in these patients need to be urgently assessed to decrease morbidity and societal burden. Lactate dehydrogenase (LDH) has been associated with worse outcomes i... | covid-19;coronavirus;lactate dehydrogenase | Journal Article;Review | Henry, Brandon Michael;Aggarwal, Gaurav;Wong, Johnny;Benoit, Stefanie;Vikse, Jens;Plebani, Mario;Lippi, Giuseppe | 10.1016/j.ajem.2020.05.073 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. [Abstract]: Coronavirus disease 2019 (COVID-19) infection has now reached a pandemic state, affecting more than a million patients worldwide. Predictors of disease outcomes in these patients need... |
32,401,611 | Hum Vaccin Immunother | The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. | We are proposingA the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the immune system to successfully stave off the infection. | coronavirus;sars-cov-2;liposome | Journal Article | Feliciello, Isidoro;Procino, Alfredo | 10.1080/21645515.2020.1758534 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. [Abstract]: We are proposingA the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the i... |
32,362,193 | Expert Rev Anti Infect Ther | Quadruple therapy for asymptomatic COVID-19 infection patients. | INTRODUCTION: The novel coronavirus (COVID-19) is currently in epidemic stage. After large-scale interpersonal infection, asymptomatic patients appear. Whether asymptomatic patients are contagious or not and whether they need medication are the arguments among clinical experts. AREAS COVERED: This paper reports a speci... | covid-19;ifn-alpha;adverse drug reaction;arbidol;asymptomatic;lopinavir;ritonavir | Case Reports;Journal Article | Wang, Ling;Xu, Xiaopeng;Ruan, Junshan;Lin, Saijin;Jiang, Jinhua;Ye, Hong | 10.1080/14787210.2020.1758066 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Quadruple therapy for asymptomatic COVID-19 infection patients. [Abstract]: INTRODUCTION: The novel coronavirus (COVID-19) is currently in epidemic stage. After large-scale interpersonal infection, asymptomatic patients appear. Whether asymptomatic patients are contagious or not and whether they need medicatio... |
32,492,092 | JAMA Pediatr | Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York. | Importance: Descriptions of the coronavirus disease 2019 (COVID-19) experience in pediatrics will help inform clinical practices and infection prevention and control for pediatric facilities. Objective: To describe the epidemiology, clinical, and laboratory features of patients with COVID-19 hospitalized at a children'... | Journal Article | Zachariah, Philip;Johnson, Candace L;Halabi, Katia C;Ahn, Danielle;Sen, Anita I;Fischer, Avital;Banker, Sumeet L;Giordano, Mirna;Manice, Christina S;Diamond, Rebekah;Sewell, Taylor B;Schweickert, Adam J;Babineau, John R;Carter, R Colin;Fenster, Daniel B;Orange, Jordan S;McCann, Teresa A;Kernie, Steven G;Saiman, Lisa | 10.1001/jamapediatrics.2020.2430 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York. [Abstract]: Importance: Descriptions of the coronavirus disease 2019 (COVID-19) experience in pediatrics will help inform clinical practices and infect... | |
32,933,618 | Biomed Environ Sci | Public Awareness and Mask Usage during the COVID-19 Epidemic: A Survey by China CDC New Media. | An online survey conducted March 18-19, 2020 on the official China CDC WeChat account platform was used to evaluate the effect of public education about masks usage during the new coronavirus disease 2019 (COVID-19) epidemic. Chinese nationals older than 18 were eligible for the survey. The survey collected 5,761 quest... | covid-19;mask;public awareness;public behaviors;social media platform | Letter | Sun, Cheng Xi;He, Bin;Mu, Di;Li, Pei Long;Zhao, Hong Ting;Li, Zhi Li;Zhang, Mu Li;Feng, Lu Zhao;Zheng, Jian Dong;Cheng, Ying;Cui, Ying;Li, Zhong Jie | 10.3967/bes2020.085 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Public Awareness and Mask Usage during the COVID-19 Epidemic: A Survey by China CDC New Media. [Abstract]: An online survey conducted March 18-19, 2020 on the official China CDC WeChat account platform was used to evaluate the effect of public education about masks usage during the new coronavirus disease 2019... |
32,758,872 | Med Hypotheses | N95/N99 peri-procedure diapers during lower gastrointestinal endoscopies. | It is important to consider lower gastrointestinal endoscopies (LGIE) as aerosol-generating procedures. Thus, it may be better to protect room environments by ensuring patients wearing peri-procedure diapers (PPD) to contain infectious colorectal gas expulsions because fecal SARS-CoV-2 has been detected among COVID-19 ... | Letter | Gupta, Deepak | 10.1016/j.mehy.2020.110026 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: N95/N99 peri-procedure diapers during lower gastrointestinal endoscopies. [Abstract]: It is important to consider lower gastrointestinal endoscopies (LGIE) as aerosol-generating procedures. Thus, it may be better to protect room environments by ensuring patients wearing peri-procedure diapers (PPD) to contain ... | |
32,904,626 | Chaos Solitons Fractals | Complex dynamics in susceptible-infected models for COVID-19 with multi-drug resistance. | Nowadays, exploring complex dynamic of epidemic models becomes a focal point for research after the outbreak of COVID-19 pandemic which has no vaccine or fully approved drug treatment up till now. Hence, complex dynamics in a susceptible-infected (SI) model for COVID-19 with multi-drug resistance (MDR) and its fraction... | chaos;fractional-order;multi-drug resistance (mdr);new frh stability conditions;susceptible-infected (si) model | Journal Article | Matouk, A E | 10.1016/j.chaos.2020.110257 | [
0,
0,
0,
0,
0,
1,
0
] | [Title]: Complex dynamics in susceptible-infected models for COVID-19 with multi-drug resistance. [Abstract]: Nowadays, exploring complex dynamic of epidemic models becomes a focal point for research after the outbreak of COVID-19 pandemic which has no vaccine or fully approved drug treatment up till now. Hence, comple... |
32,797,228 | Clin Infect Dis | Potential antigenic cross-reactivity between SARS-CoV-2 and Dengue viruses. | BACKGROUND: COVID-19 and dengue fever are difficult to distinguish given shared clinical and laboratory features. Failing to consider COVID-19 due to false-positive dengue serology can have serious implications. We aimed to assess this possible cross reactivity. METHODS: We analyzed clinical data and serum samples from... | covid-19;dengue;west nile | Journal Article | Lustig, Yaniv;Keler, Shlomit;Kolodny, Rachel;Ben-Tal, Nir;Atias-Varon, Danit;Shlush, Ekaterina;Gerlic, Motti;Munitz, Ariel;Doolman, Ram;Asraf, Keren;Shlush, Liran I;Vivante, Asaf | 10.1093/cid/ciaa1207 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Potential antigenic cross-reactivity between SARS-CoV-2 and Dengue viruses. [Abstract]: BACKGROUND: COVID-19 and dengue fever are difficult to distinguish given shared clinical and laboratory features. Failing to consider COVID-19 due to false-positive dengue serology can have serious implications. We aimed to... |
32,306,047 | Clin Infect Dis | Antibody Detection and Dynamic Characteristics in Patients With Coronavirus Disease 2019. | BACKGROUND: The coronavirus disease 2019 (COVID-19), caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been rapidly spreading nationwide and abroad. A serologic test to identify antibody dynamics and response to SARS-CoV-2 was developed. METHODS: The antibodies against SARS-... | covid-19;elisa;sars-cov-2;diagnosis;serological test | Journal Article | Xiang, Fei;Wang, Xiaorong;He, Xinliang;Peng, Zhenghong;Yang, Bohan;Zhang, Jianchu;Zhou, Qiong;Ye, Hong;Ma, Yanling;Li, Hui;Wei, Xiaoshan;Cai, Pengcheng;Ma, Wan-Li | 10.1093/cid/ciaa461 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Antibody Detection and Dynamic Characteristics in Patients With Coronavirus Disease 2019. [Abstract]: BACKGROUND: The coronavirus disease 2019 (COVID-19), caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been rapidly spreading nationwide and abroad. A serologic tes... |
32,441,666 | Clin Chem Lab Med | Dynamic profile and clinical implications of hematological parameters in hospitalized patients with coronavirus disease 2019. | Objectives As people across the world suffer from coronavirus disease 2019 (COVID-19), further studies are needed to facilitate evaluating the severity and prognosis of COVID-19 patients. In the study, we aimed to dissect the dynamic profile and clinical implications of hematological findings in hospitalized patients w... | coronavirus disease 2019;hematological parameters;hospitalization time;neutrophil-to-lymphocyte ratio;severe acute respiratory syndrome coronavirus 2 | Journal Article | Ding, Xiurong;Yu, Yanhua;Lu, Bichao;Huo, Jianbo;Chen, Ming;Kang, Yanfang;Lou, Jinli;Liu, Zhizhong | 10.1515/cclm-2020-0411 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Dynamic profile and clinical implications of hematological parameters in hospitalized patients with coronavirus disease 2019. [Abstract]: Objectives As people across the world suffer from coronavirus disease 2019 (COVID-19), further studies are needed to facilitate evaluating the severity and prognosis of COVI... |
33,024,578 | Cell Death Discov | Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2. | The hand of molecular mimicry in shaping SARS-CoV-2 evolution and immune evasion remains to be deciphered. Here, we report 33 distinct 8-mer/9-mer peptides that are identical between SARS-CoV-2 and the human reference proteome. We benchmark this observation against other viral-human 8-mer/9-mer peptide identity, which ... | environmental microbiology;proteomics | Journal Article | Venkatakrishnan, A J;Kayal, Nikhil;Anand, Praveen;Badley, Andrew D;Church, George M;Soundararajan, Venky | 10.1038/s41420-020-00321-y | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2. [Abstract]: The hand of molecular mimicry in shaping SARS-CoV-2 evolution and immune evasion remains to be deciphered. Here, we report 33 distinct 8-mer/9-mer pep... |
32,962,623 | Recent Pat Antiinfect Drug Discov | The Role of Tocilizumab in Cytokine Storm and Improving Outcomes in COVID-19. | To date, severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2) has infected millions of individuals worldwide. This virus causes coronavirus disease 2019 (COVID-19) and has led to numerous deaths worldwide. A large percentage of infected patients present asymptomatically, augmenting the spread of the virus. Symp... | covid-19;il-6;sars-cov-2;tocilizumab;cytokine release syndrome;cytokine storm | Journal Article;Review | Ali, Afroze;Kamjani, Milad H;Kesselman, Marc M | 10.2174/1574891X15666200922155712 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The Role of Tocilizumab in Cytokine Storm and Improving Outcomes in COVID-19. [Abstract]: To date, severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2) has infected millions of individuals worldwide. This virus causes coronavirus disease 2019 (COVID-19) and has led to numerous deaths worldwide. A large... |
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