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32,566,483
IDCases
Doxycycline as a potential partner of COVID-19 therapies.
Coronavirus disease 2019 (COVID-19) is a major public health challenge, and the current antiviral arsenal for treatment is limited, with questionable efficacy. Major efforts are under way for discovery of new effective agents, but the validation of new potential treatments for COVID-19 may take a long time. Therefore, ...
2019 novel coronavirus;covid-19;doxycycline;hydroxychloroquine;remdesivir
Editorial
Malek, Alexandre E;Granwehr, Bruno P;Kontoyiannis, Dimitrios P
10.1016/j.idcr.2020.e00864
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Doxycycline as a potential partner of COVID-19 therapies. [Abstract]: Coronavirus disease 2019 (COVID-19) is a major public health challenge, and the current antiviral arsenal for treatment is limited, with questionable efficacy. Major efforts are under way for discovery of new effective agents, but the valida...
32,875,494
J Gen Intern Med
Cross-Sectional Prevalence of SARS-CoV-2 Among Skilled Nursing Facility Employees and Residents Across Facilities in Seattle.
BACKGROUND: Skilled nursing facilities (SNFs) are high-risk settings for SARS-CoV-2 transmission. Infection rates among employees are infrequently described. OBJECTIVE: To describe SARS-CoV-2 rates among SNF employees and residents during a non-outbreak time period, we measured cross-sectional SARS-CoV-2 prevalence acr...
sars-cov-2;skilled nursing facility
Journal Article;Multicenter Study
Weil, Ana A;Newman, Kira L;Ong, Thuan D;Davidson, Giana H;Logue, Jennifer;Brandstetter, Elisabeth;Magedson, Ariana;McDonald, Dylan;McCulloch, Denise J;Neme, Santiago;Lewis, James;Duchin, Jeff S;Zhong, Weizhi;Starita, Lea M;Bedford, Trevor;Roxby, Alison C;Chu, Helen Y
10.1007/s11606-020-06165-7
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Cross-Sectional Prevalence of SARS-CoV-2 Among Skilled Nursing Facility Employees and Residents Across Facilities in Seattle. [Abstract]: BACKGROUND: Skilled nursing facilities (SNFs) are high-risk settings for SARS-CoV-2 transmission. Infection rates among employees are infrequently described. OBJECTIVE: To d...
32,834,374
World Dev
COVID-19 in South Korea: Lessons for developing countries.
South Korea's response is considered by many as one the most effective models against COVID-19. The average number of new cases per day fell to 6.4 in the first week of May and currently 90% of all confirmed cases have fully recovered after a massive outbreak in February 29. First, South Korea has flattened the curve o...
covid-19;contact tracing;korea;pandemic;social distancing;testing
Journal Article
Lee, Daejoong;Heo, Kyungmoo;Seo, Yongseok
10.1016/j.worlddev.2020.105057
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in South Korea: Lessons for developing countries. [Abstract]: South Korea's response is considered by many as one the most effective models against COVID-19. The average number of new cases per day fell to 6.4 in the first week of May and currently 90% of all confirmed cases have fully recovered after...
32,831,537
Phys Fluids (1994)
The dispersion of spherical droplets in source-sink flows and their relevance to the COVID-19 pandemic.
In this paper, we investigate the dynamics of spherical droplets in the presence of a source-sink pair flow field. The dynamics of the droplets is governed by the Maxey-Riley equation with the Basset-Boussinesq history term neglected. We find that, in the absence of gravity, there are two distinct behaviors for the dro...
Journal Article
Cummins, C P;Ajayi, O J;Mehendale, F V;Gabl, R;Viola, I M
10.1063/5.0021427
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The dispersion of spherical droplets in source-sink flows and their relevance to the COVID-19 pandemic. [Abstract]: In this paper, we investigate the dynamics of spherical droplets in the presence of a source-sink pair flow field. The dynamics of the droplets is governed by the Maxey-Riley equation with the Ba...
32,880,335
S Afr Med J
Comorbidity in context: Part 1. Medical considerations around HIV and tuberculosis during the COVID-19 pandemic in South Africa.
Infectious diseases pandemics have devastating health, social and economic consequences, especially in developing countries such as South Africa. Scarce medical resources must often be rationed effectively to contain the disease outbreak. In the case of COVID-19, even the best-resourced countries will have inadequate i...
Journal Article
Rossouw, T M;Boswell, M T;Nienaber, A G;Moodley, K
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Comorbidity in context: Part 1. Medical considerations around HIV and tuberculosis during the COVID-19 pandemic in South Africa. [Abstract]: Infectious diseases pandemics have devastating health, social and economic consequences, especially in developing countries such as South Africa. Scarce medical resources...
32,834,893
World Allergy Organ J
Does hereditary angioedema make COVID-19 worse?
The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19, enters host cells via angiotensin-converting enzyme 2 (ACE2) and depletes ACE2, which is necessary for bradykinin metabolism. The depletion of AC...
ace2;adam metallopeptidase domain 17, adam17;c1 inhibitor, c1-inh;covid-19;complement system;contact system;coronavirus disease 2019, covid-19;hereditary angioedema;middle east respiratory syndrome coronavirus, mers-cov;acute respiratory distress syndrome, ards;angiotensin-converting enzyme, ace;bradykinin receptor b1,...
Journal Article;Review
Xu, Yingyang;Liu, Shuang;Zhang, Yan;Zhi, Yuxiang
10.1016/j.waojou.2020.100454
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Does hereditary angioedema make COVID-19 worse? [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19, enters host cells via angiotensin-converting enzyme 2 (ACE2) and depletes AC...
32,828,084
J Chem Phys
Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states.
In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). Spike (S) glycoproteins on the viral membrane bind to ACE2 receptors on the host cell membrane and initiate fusion, and S protein is currently amo...
Journal Article
Gur, Mert;Taka, Elhan;Yilmaz, Sema Zeynep;Kilinc, Ceren;Aktas, Umut;Golcuk, Mert
10.1063/5.0011141
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states. [Abstract]: In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). Spike (S) glycoproteins on the...
32,726,723
Int J Infect Dis
Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections.
This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infection. Patients with olfactory/taste disorders (OTDs) exhibited lower qPCR Ct values and longer time to negative qPCR than those without OTDs, sugges...
covid-19;cycle threshold (ct) values;olfactory/taste disorders (otds);real-time polymerase chain reaction (qpcr);sars-cov-2
Journal Article
Nakagawara, Kensuke;Masaki, Katsunori;Uwamino, Yoshifumi;Kabata, Hiroki;Uchida, Sho;Uno, Shunsuke;Asakura, Takanori;Funakoshi, Takeru;Kanzaki, Sho;Ishii, Makoto;Hasegawa, Naoki;Fukunaga, Koichi
10.1016/j.ijid.2020.07.034
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections. [Abstract]: This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infecti...
32,555,138
MMWR Morb Mortal Wkly Rep
Public Attitudes, Behaviors, and Beliefs Related to COVID-19, Stay-at-Home Orders, Nonessential Business Closures, and Public Health Guidance - United States, New York City, and Los Angeles, May 5-12, 2020.
SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is thought to be transmitted mainly by person-to-person contact (1). Implementation of nationwide public health orders to limit person-to-person interaction and of guidance on personal protective practices can slow transmission (2,3). Such strategie...
Journal Article
Czeisler, Mark E;Tynan, Michael A;Howard, Mark E;Honeycutt, Sally;Fulmer, Erika B;Kidder, Daniel P;Robbins, Rebecca;Barger, Laura K;Facer-Childs, Elise R;Baldwin, Grant;Rajaratnam, Shantha M W;Czeisler, Charles A
10.15585/mmwr.mm6924e1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public Attitudes, Behaviors, and Beliefs Related to COVID-19, Stay-at-Home Orders, Nonessential Business Closures, and Public Health Guidance - United States, New York City, and Los Angeles, May 5-12, 2020. [Abstract]: SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is thought to be tran...
32,986,664
Hum Antibodies
COVID-19: Significance of antibodies.
The newly emerged severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has recently caused pandemic Coronavirus Disease-2019 (COVID-19). Considering the serious medical, economic and social consequences of this pandemic and the lack of definite medication and vaccine it is necessary to describe natural ...
covid-19;sars-cov-2;corona virus;neutralizing antibodies;serological test
Journal Article;Review
Assadiasl, Sara;Fatahi, Yousef;Zavvar, Mahdi;Nicknam, Mohammad Hossein
10.3233/HAB-200429
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Significance of antibodies. [Abstract]: The newly emerged severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has recently caused pandemic Coronavirus Disease-2019 (COVID-19). Considering the serious medical, economic and social consequences of this pandemic and the lack of definite ...
33,033,574
World J Radiol
Review of X-ray and computed tomography scan findings with a promising role of point of care ultrasound in COVID-19 pandemic.
As healthcare professionals continue to combat the coronavirus disease 2019 (COVID-19) infection worldwide, there is an increasing interest in the role of imaging and the relevance of various modalities. Since imaging not only helps assess the disease at the time of diagnosis but also aids evaluation of response to man...
covid-19;computed tomography;coronavirus;point of care ultrasound;wuhan;x-ray
Journal Article;Review
Gandhi, Darshan;Ahuja, Kriti;Grover, Hemal;Sharma, Pranav;Solanki, Shantanu;Gupta, Nishant;Patel, Love
10.4329/wjr.v12.i9.195
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Review of X-ray and computed tomography scan findings with a promising role of point of care ultrasound in COVID-19 pandemic. [Abstract]: As healthcare professionals continue to combat the coronavirus disease 2019 (COVID-19) infection worldwide, there is an increasing interest in the role of imaging and the re...
32,425,485
Enferm Clin
[ELDERLY PEOPLE, DEPENDENCY AND VULNERABILITY IN THE CORONAVIRUS PANDEMIC: AN EMERGENCY FOR A SOCIAL AND HEALTH INTEGRATION.]
The current SARS-CoV-2 pandemic (COVID-19) is affecting elderly people worldwide with greater incidence and severity. In Spain, 68% of all coronavirus hospitalizations correspond to those over 60 years of age. This work aims to highlight the evidence about the measures to be implemented through current and future guide...
covid-19;elderly;health services for the elderly;health vulnerability;institutional policy;social services
Journal Article
Galvez, Ana M feminine Porcel;Romero, Barbara Badanta;Trigo, Sergio Barrientos;Serrano, Marta Lima
10.1016/j.enfcli.2020.05.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [ELDERLY PEOPLE, DEPENDENCY AND VULNERABILITY IN THE CORONAVIRUS PANDEMIC: AN EMERGENCY FOR A SOCIAL AND HEALTH INTEGRATION.] [Abstract]: The current SARS-CoV-2 pandemic (COVID-19) is affecting elderly people worldwide with greater incidence and severity. In Spain, 68% of all coronavirus hospitalizations corre...
33,049,360
Travel Med Infect Dis
Incidence of COVID-19 among returning travelers in quarantine facilities: A longitudinal study and lessons learned.
INTRODUCTION: The emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) had resulted in an unpresented global pandemic. In the initial events, the Kingdom of Saudi Arabia implemented mandatory quarantine of returning travelers in order to contain COVID-19 cases. MATERIALS AND METHODS: This is a ...
covid-19;quarantine;sars-cov-2;travelers
Journal Article
Al-Tawfiq, Jaffar A;Sattar, Amar;Al-Khadra, Husain;Al-Qahtani, Saeed;Al-Mulhim, Mobarak;Al-Omoush, Omar;Kheir, Hatim O
10.1016/j.tmaid.2020.101901
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Incidence of COVID-19 among returning travelers in quarantine facilities: A longitudinal study and lessons learned. [Abstract]: INTRODUCTION: The emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) had resulted in an unpresented global pandemic. In the initial events, the Kingdom of S...
32,605,661
Genome Med
Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples.
BACKGROUND: COVID-19 (coronavirus disease 2019) has caused a major epidemic worldwide; however, much is yet to be known about the epidemiology and evolution of the virus partly due to the scarcity of full-length SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) genomes reported. One reason is that the challe...
covid-19;emerging infectious diseases;genomic surveillance;hybrid capture;metatranscriptomic sequencing;multiplex pcr;quasispecies;virus evolution;isnv
Journal Article;Research Support, Non-U.S. Gov't
Xiao, Minfeng;Liu, Xiaoqing;Ji, Jingkai;Li, Min;Li, Jiandong;Yang, Lin;Sun, Wanying;Ren, Peidi;Yang, Guifang;Zhao, Jincun;Liang, Tianzhu;Ren, Huahui;Chen, Tian;Zhong, Huanzi;Song, Wenchen;Wang, Yanqun;Deng, Ziqing;Zhao, Yanping;Ou, Zhihua;Wang, Daxi;Cai, Jielun;Cheng, Xinyi;Feng, Taiqing;Wu, Honglong;Gong, Yanping;Yang...
10.1186/s13073-020-00751-4
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples. [Abstract]: BACKGROUND: COVID-19 (coronavirus disease 2019) has caused a major epidemic worldwide; however, much is yet to be known about the epidemiology and evolution of the virus partly due to the sca...
33,059,771
Trials
Double-Blind, Randomized, Placebo-Controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of treating Healthcare Professionals with the Adsorbed COVID-19 (Inactivated) Vaccine Manufactured by Sinovac - PROFISCOV: A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: To evaluate the efficacy of two doses of the adsorbed vaccine COVID-19 (inactivated) produced by Sinovac in symptomatic individuals, with virological confirmation of COVID-19, two weeks after the completion of the two-dose vaccination regimen, aged 18 years or older who work as health professionals providin...
brazil;covid-19;covid-19 vaccine;inactivated vaccines;phase iii clinical trial;randomised controlled trial;protocol
Clinical Trial, Phase III;Letter;Multicenter Study;Randomized Controlled Trial
Palacios, Ricardo;Patino, Elizabeth Gonzalez;de Oliveira Piorelli, Roberta;Conde, Monica Tilli Reis Pessoa;Batista, Ana Paula;Zeng, Gang;Xin, Qianqian;Kallas, Esper G;Flores, Jorge;Ockenhouse, Christian F;Gast, Christopher
10.1186/s13063-020-04775-4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Double-Blind, Randomized, Placebo-Controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of treating Healthcare Professionals with the Adsorbed COVID-19 (Inactivated) Vaccine Manufactured by Sinovac - PROFISCOV: A structured summary of a study protocol for a randomised controlled trial. [Abstr...
32,833,777
Crit Care Nurs Q
Isolation Requirements and Personal Protective Equipment in the COVID-19 Pandemic.
Isolation requirements and subsequent need for personal protective equipment (PPE) are among the many challenges associated with the COVID-19 pandemic. Isolation of COVID-19-positive patients and the use of appropriate PPE by health care professionals are important parts of infection prevention, not only in the hospita...
Journal Article
Rabold, Erica;Rovnan, Helene;DuMont, Tiffany
10.1097/CNQ.0000000000000326
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Isolation Requirements and Personal Protective Equipment in the COVID-19 Pandemic. [Abstract]: Isolation requirements and subsequent need for personal protective equipment (PPE) are among the many challenges associated with the COVID-19 pandemic. Isolation of COVID-19-positive patients and the use of appropria...
33,050,914
BMC Oral Health
Assessment of knowledge and practice of dentists towards Coronavirus Disease (COVID-19): a cross-sectional survey from Lebanon.
BACKGROUND: Coronavirus Disease (COVID-19) epidemic is a public health emergency of international concern. Dentists are exposed to the enormous risk of COVID-19 infection during this epidemic. This study aims to assess the knowledge and practice of dentists toward the COVID-19 epidemic in Lebanon. METHODS: We conducted...
covid-19;coronavirus;dentist;knowledge;lebanon;practice
Journal Article
Nasser, Zeina;Fares, Youssef;Daoud, Rama;Abou-Abbas, Linda
10.1186/s12903-020-01273-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Assessment of knowledge and practice of dentists towards Coronavirus Disease (COVID-19): a cross-sectional survey from Lebanon. [Abstract]: BACKGROUND: Coronavirus Disease (COVID-19) epidemic is a public health emergency of international concern. Dentists are exposed to the enormous risk of COVID-19 infection ...
32,922,212
Thromb J
Thrombotic events following tocilizumab therapy in critically ill COVID-19 patients: a Facade for prognostic markers.
Background: Hospitals in the Middle East Gulf region have experienced an influx of COVID-19 patients to their medical wards and intensive care units. The hypercoagulability of these patients has been widely reported on a global scale. However, many of the experimental treatments used to manage the various complications...
covid-19;d-dimers;prognostic markers;thrombosis;tocilizumab
Case Reports
Atallah, Bassam;El Nekidy, Wasim;Mallah, Saad I;Cherfan, Antoine;AbdelWareth, Laila;Mallat, Jihad;Hamed, Fadi
10.1186/s12959-020-00236-9
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Thrombotic events following tocilizumab therapy in critically ill COVID-19 patients: a Facade for prognostic markers. [Abstract]: Background: Hospitals in the Middle East Gulf region have experienced an influx of COVID-19 patients to their medical wards and intensive care units. The hypercoagulability of these...
32,657,171
COPD
The COVID-19 Pandemic Confronts the Motivation Fallacy within Pulmonary Rehabilitation Programs.
Social distancing and quarantines have been implemented worldwide to reduce the spread of Coronavirus Disease (COVID-19). However, social distancing has had far-reaching health consequences, considering that the COVID-19 pandemic has exposed people to the hazard of physical inactivity and sedentary behavior. For patien...
covid-19;chronic obstructive;pulmonary disease;motivation;pulmonary rehabilitation
Journal Article;Research Support, Non-U.S. Gov't;Review
Karloh, Manuela;Sousa Matias, Thiago;Fleig Mayer, Anamaria
10.1080/15412555.2020.1790511
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 Pandemic Confronts the Motivation Fallacy within Pulmonary Rehabilitation Programs. [Abstract]: Social distancing and quarantines have been implemented worldwide to reduce the spread of Coronavirus Disease (COVID-19). However, social distancing has had far-reaching health consequences, considering...
32,880,584
J Med Internet Res
Current Challenges of Digital Health Interventions in Pakistan: Mixed Methods Analysis.
BACKGROUND: Digital health is well-positioned in low and middle-income countries (LMICs) to revolutionize health care due, in part, to increasing mobile phone access and internet connectivity. This paper evaluates the underlying factors that can potentially facilitate or hinder the progress of digital health in Pakista...
lmics;pakistan;swot;digital health;ehealth;mhealth;telehealth
Journal Article;Research Support, Non-U.S. Gov't
Kazi, Abdul Momin;Qazi, Saad Ahmed;Ahsan, Nazia;Khawaja, Sadori;Sameen, Fareeha;Saqib, Muhammad;Khan Mughal, Muhammad Ayub;Wajidali, Zabin;Ali, Sikander;Ahmed, Rao Moueed;Kalimuddin, Hussain;Rauf, Yasir;Mahmood, Fatima;Zafar, Saad;Abbasi, Tufail Ahmad;Khoumbati, Khalil-Ur-Rahmen;Abbasi, Munir A;Stergioulas, Lampros K
10.2196/21691
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Current Challenges of Digital Health Interventions in Pakistan: Mixed Methods Analysis. [Abstract]: BACKGROUND: Digital health is well-positioned in low and middle-income countries (LMICs) to revolutionize health care due, in part, to increasing mobile phone access and internet connectivity. This paper evaluat...
32,508,257
Tumori
Patients with cancer in the COVID-19 era: the clinical trial issue.
Coronavirus disease 2019 (COVID-19) hospital reorganization may result in reduced ability for the hospital to fully use its armamentarium for battling cancer. Thus different therapeutic modalities have been recommended. During the pandemic, despite regulatory agencies' recommendations, several considerations and doubts...
covid-19;clinical trials;oncology
Editorial
Scarcia, Marcello;Ludovico, Giuseppe Mario;Fortunato, Angela;Fiorentino, Alba
10.1177/0300891620933672
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patients with cancer in the COVID-19 era: the clinical trial issue. [Abstract]: Coronavirus disease 2019 (COVID-19) hospital reorganization may result in reduced ability for the hospital to fully use its armamentarium for battling cancer. Thus different therapeutic modalities have been recommended. During the ...
32,838,162
SN Compr Clin Med
Let Us Not Forget Cardiovascular Diseases During COVID-19 Pandemic: the Role of Cardiac Prevention and Rehabilitation.
During novel coronavirus disease (COVID-19) pandemic, major focus of health service is on mitigating the spread of infection and treating the acute severe respiratory syndrome of affected patients. However, from available initial data, it has been shown that cardiovascular and metabolic diseases are responsible for a w...
covid-19;cardiac rehabilitation;exercise;pandemic;prevention;sars-cov2
Journal Article
Galiuto, Leonarda;Crea, Filippo
10.1007/s42399-020-00391-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Let Us Not Forget Cardiovascular Diseases During COVID-19 Pandemic: the Role of Cardiac Prevention and Rehabilitation. [Abstract]: During novel coronavirus disease (COVID-19) pandemic, major focus of health service is on mitigating the spread of infection and treating the acute severe respiratory syndrome of a...
32,358,954
Clin Infect Dis
Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing.
BACKGROUND: To explore and describe the current literature surrounding bacterial/fungal coinfection in patients with coronavirus infection. METHODS: MEDLINE, EMBASE, and Web of Science were searched using broad-based search criteria relating to coronavirus and bacterial coinfection. Articles presenting clinical data fo...
sars-cov-2;antimicrobial resistance;antimicrobial stewardship
Journal Article;Research Support, Non-U.S. Gov't;Review
Rawson, Timothy M;Moore, Luke S P;Zhu, Nina;Ranganathan, Nishanthy;Skolimowska, Keira;Gilchrist, Mark;Satta, Giovanni;Cooke, Graham;Holmes, Alison
10.1093/cid/ciaa530
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing. [Abstract]: BACKGROUND: To explore and describe the current literature surrounding bacterial/fungal coinfection in patients with coronavirus infection. METHODS: MEDLINE, EMBASE, and W...
32,557,905
J Card Surg
Impact of COVID-19 on cardiac surgical training: Our experience in the United Kingdom.
The current evolving global pandemic caused by coronavirus disease-2019 (COVID-19) has dramatically impacted global health care systems, resulting in governments taking unprecedented measures to contain the spread of the infection, with adaptations by health care organizations. Research into understanding the pathophys...
covid-19;cardiac surgery;surgical training
Journal Article
Shafi, Ahmed M A;Atieh, Abed Elfattah;Harky, Amer;Sheikh, Amir M;Awad, Wael I
10.1111/jocs.14693
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on cardiac surgical training: Our experience in the United Kingdom. [Abstract]: The current evolving global pandemic caused by coronavirus disease-2019 (COVID-19) has dramatically impacted global health care systems, resulting in governments taking unprecedented measures to contain the sprea...
32,826,081
Semin Perinatol
A review of newborn outcomes during the COVID-19 pandemic.
As the COVID-19 pandemic continues to spread worldwide, it is crucial that we determine populations that are at-risk and develop appropriate clinical care policies to protect them. While several respiratory illnesses are known to seriously impact pregnant women and newborns, preliminary data on the novel SARS-CoV-2 Cor...
Journal Article;Review
Kyle, Margaret H;Glassman, Melissa E;Khan, Adrita;Fernandez, Cristina R;Hanft, Erin;Emeruwa, Ukachi N;Scripps, Tessa;Walzer, Lauren;Liao, Grace V;Saslaw, Minna;Rubenstein, David;Hirsch, Daniel S;Keown, M Kathleen;Stephens, Ashley;Mollicone, Isabelle;Bence, Mary L;Gupta, Archana;Sultan, Sally;Sibblies, Caroline;Whittier...
10.1016/j.semperi.2020.151286
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A review of newborn outcomes during the COVID-19 pandemic. [Abstract]: As the COVID-19 pandemic continues to spread worldwide, it is crucial that we determine populations that are at-risk and develop appropriate clinical care policies to protect them. While several respiratory illnesses are known to seriously ...
32,719,807
Front Med (Lausanne)
Non-pharmaceutical Interventions for Pandemic COVID-19: A Cross-Sectional Investigation of US General Public Beliefs, Attitudes, and Actions.
Non-pharmaceutical interventions (NPIs) represent the primary mitigation strategy for the COVID-19 pandemic. Despite this, many government agencies and members of the general public may be resistant to NPI adoption. We sought to understand public attitudes and beliefs regarding various NPIs and self-reported adoption o...
covid- 19;sars-cov-2;non-pharmaceutical interventions;public attitudes;quarantine
Journal Article
Kantor, Bella Nichole;Kantor, Jonathan
10.3389/fmed.2020.00384
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Non-pharmaceutical Interventions for Pandemic COVID-19: A Cross-Sectional Investigation of US General Public Beliefs, Attitudes, and Actions. [Abstract]: Non-pharmaceutical interventions (NPIs) represent the primary mitigation strategy for the COVID-19 pandemic. Despite this, many government agencies and membe...
32,816,230
Head Neck Pathol
ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review.
To review the data regarding the expression of angiotensin converting enzyme-2 (ACE2) and transmembrane protease serine-2 (TMPRSS2) in head and neck tissue. Scopus, Cochrane Library, Medrxiv, Google Scholar and PubMED/MEDLINE were searched by four independent investigators for studies investigating ACE2 or TMPRSS2 expr...
ace2;covid;coronavirus;head neck;sars-cov-2;tmprss2
Journal Article;Systematic Review
Lechien, Jerome R;Radulesco, Thomas;Calvo-Henriquez, Christian;Chiesa-Estomba, Carlos M;Hans, Stephane;Barillari, Maria R;Cammaroto, Giovanni;Descamps, Geraldine;Hsieh, Julien;Vaira, Luigi;De Riu, Giacomo;Sowerby, Leigh;Gengler, Isabelle;Michel, Justin;Saussez, Sven
10.1007/s12105-020-01212-5
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review. [Abstract]: To review the data regarding the expression of angiotensin converting enzyme-2 (ACE2) and transmembrane protease serine-2 (TMPRSS2) in head and neck tissue. Scopus, Cochrane Library, Medrxiv, Google Scholar and PubMED/MEDLINE w...
32,286,242
Clin Chem Lab Med
The value of urine biochemical parameters in the prediction of the severity of coronavirus disease 2019.
Background Among patients with coronavirus disease 2019 (COVID-19), the cases of a significant proportion of patients are severe. A viral nucleic acid test is used for the diagnosis of COVID-19, and some hematological indicators have been used in the auxiliary diagnosis and identification of the severity of COVID-19. R...
covid-19;sars-cov-2;urine biochemical parameters
Journal Article;Research Support, Non-U.S. Gov't
Liu, Rui;Ma, Qingfeng;Han, Huan;Su, Hanwen;Liu, Fang;Wu, Kailang;Wang, Wei;Zhu, Chengliang
10.1515/cclm-2020-0220
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The value of urine biochemical parameters in the prediction of the severity of coronavirus disease 2019. [Abstract]: Background Among patients with coronavirus disease 2019 (COVID-19), the cases of a significant proportion of patients are severe. A viral nucleic acid test is used for the diagnosis of COVID-19,...
32,852,238
J Aerosol Med Pulm Drug Deliv
Uninterrupted Continuous and Intermittent Nebulizer Therapy in a COVID-19 Patient Using Sequential Vibratory Mesh Nebulizers: A Case Report.
Interruptions in continuous nebulized pulmonary vasodilators, such as epoprostenol, can potentially result in clinical deterioration in respiratory status. Coadministration of other intermittent nebulized therapies may require opening the ventilator circuit to facilitate administration. However, in patients with SARS-C...
covid-19;epoprostenol;mucolytics;nebulized antibiotics
Case Reports
Elnadoury, Ola;Beattie, Jason;Lubinsky, Anthony S
10.1089/jamp.2020.1636
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Uninterrupted Continuous and Intermittent Nebulizer Therapy in a COVID-19 Patient Using Sequential Vibratory Mesh Nebulizers: A Case Report. [Abstract]: Interruptions in continuous nebulized pulmonary vasodilators, such as epoprostenol, can potentially result in clinical deterioration in respiratory status. Co...
32,938,496
Trials
Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV and other viral pneumonia are associated with an over-exuberant cytokine release. Elevated levels of blood IL-6 had been identified as a one of the risk factors associated with severe COVID-19 disease. Anti-IL6...
covid-19;randomised controlled trial;sars-cov-2;anti-il6 inhibitor;corticosteroids;early intervention;protocol;sarilumab;severe interstitial pneumonia
Clinical Trial Protocol;Letter
Caballero Bermejo, Antonio F;Ruiz-Antoran, Belen;Fernandez Cruz, Ana;Diago Sempere, Elena;Callejas Diaz, Alejandro;Munez Rubio, Elena;Avendano-Sola, Cristina;Ramos Martinez, Antonio;Sancho Lopez, Aranzazu
10.1186/s13063-020-04633-3
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV...
32,283,711
Cells
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells.
In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence similarity and the use of the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), with severe acute respiratory syndrome coronavirus (SARS-CoV). Seve...
ace2;sars-cov-2;infection;scrna-seq;spermatogonia
Journal Article;Research Support, N.I.H., Intramural
Wang, Zhengpin;Xu, Xiaojiang
10.3390/cells9040920
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells. [Abstract]: In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both...
32,524,147
J Am Med Inform Assoc
What patients "see" doctors in online fever clinics during COVID-19 in Wuhan?
OBJECTIVE: In December 2019, coronavirus disease 2019 (COVID-19) occurred in Wuhan, China. Online fever clinics were developed by hospitals, largely relieving the hospital's burden. Online fever clinics could help people stay out of crowded hospitals and prevent the risk of cross infections. The objective of our study ...
covid-19;consumer health informatics;descriptive research;online fever clinic;online health
Journal Article;Research Support, Non-U.S. Gov't
Li, Gang;Fan, Guorui;Chen, Yanyan;Deng, Zhaohua
10.1093/jamia/ocaa062
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: What patients "see" doctors in online fever clinics during COVID-19 in Wuhan? [Abstract]: OBJECTIVE: In December 2019, coronavirus disease 2019 (COVID-19) occurred in Wuhan, China. Online fever clinics were developed by hospitals, largely relieving the hospital's burden. Online fever clinics could help people ...
32,568,212
J Alzheimers Dis
Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19.
The coronavirus disease 2019 (COVID-19) pandemic led to an abrupt halt of many Alzheimer's disease (AD) research studies at sites spanning the world. This is especially true for studies requiring in-person contact, such as studies collecting biofluids. Since COVID-19 is likely to remain a threat for an extended period,...
alzheimer's disease;covid-19;biofluids;biomarkers;safety
Letter
Schindler, Suzanne E;Jicha, Gregory A;Nelson, Peter T;Keene, C Dirk;Blennow, Kaj;Molinuevo, Jose Luis;Masters, Colin L;Hansson, Oskar;Teunissen, Charlotte E;Galasko, Douglas;Shaw, Leslie M;Levey, Allan I;Silverberg, Nina
10.3233/JAD-200684
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic led to an abrupt halt of many Alzheimer's disease (AD) research studies at sites spanning the world. This is especially true for studies requirin...
32,646,911
Microbiol Resour Announc
Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Early Manifestations of COVID-19 in Israel.
We announce the genome sequences of two strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated in Israel, one imported by a traveler who returned from Japan and the second strain collected from a patient infected by a traveler returning from Italy. The sequences obtained are valuable as early ...
Journal Article
Cohen-Gihon, Inbar;Israeli, Ofir;Shifman, Ohad;Stein, Dana;Achdout, Hagit;Weiss, Shay;Mandelboim, Michal;Erster, Oran;Regev-Yochay, Gili;Segal, Gad;Yitzhaki, Shmuel;Shapira, Shmuel C;Beth-Din, Adi;Zvi, Anat
10.1128/MRA.00677-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Early Manifestations of COVID-19 in Israel. [Abstract]: We announce the genome sequences of two strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated in Israel, one imported by a traveler who returned from Japan and the...
32,837,672
Radiol Case Rep
COVID-19-associated encephalopathy with fulminant cerebral vasoconstriction: CT and MRI findings.
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) can cause various mild to severe neurologic symptoms, leading to significant morbidity and mortality. We hereby present a fatal case of a 50-year-old male health care provider, admitted due to altered mental status due to encephalopathy, cerebral edema, and f...
covid19;encephalopathy;pandemic;sars-cov-2;vasoconstriction
Case Reports
Sirous, Reza;Taghvaei, Reheleh;Hellinger, Jeffery C;Krauthamer, Alan V;Mirfendereski, Sam
10.1016/j.radcr.2020.08.024
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19-associated encephalopathy with fulminant cerebral vasoconstriction: CT and MRI findings. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) can cause various mild to severe neurologic symptoms, leading to significant morbidity and mortality. We hereby present a fatal case of a 50...
32,849,913
Ther Adv Urol
Urinary stone management during the COVID-19 pandemic: a suggested approach and review of literature.
COVID-19 is now the major health concern of the century in many countries. Prolonged homestay has various undesirable consequences for people, such as physical inactivity and weight gain, which potentially could put people at risk of urinary stone formation. With regard to the prevention and treatment strategy for urin...
covid-19;nephrolithiasis;urinary calculi
Journal Article;Review
Fakhr Yasseri, Alimohammad;Aghamir, Seyed Mohammad Kazem
10.1177/1756287220939513
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Urinary stone management during the COVID-19 pandemic: a suggested approach and review of literature. [Abstract]: COVID-19 is now the major health concern of the century in many countries. Prolonged homestay has various undesirable consequences for people, such as physical inactivity and weight gain, which pot...
33,011,717
Am J Nephrol
Acute Kidney Injury in COVID-19 Patients: An Inner City Hospital Experience and Policy Implications.
BACKGROUND: Although diffuse alveolar damage and respiratory failure are the key features of coronavirus disease 2019 (COVID-19), the involvement of other organs such as the kidney has also been reported. The reports of the incidence of acute kidney injury (AKI) in COVID-19 patients vary widely. In this study, we repor...
acute kidney injury;acute respiratory distress syndrome;coronavirus disease 19;in-hospital mortality
Journal Article
Zahid, Umar;Ramachandran, Preethi;Spitalewitz, Samuel;Alasadi, Lutfi;Chakraborti, Abhishek;Azhar, Muhammad;Mikhalina, Galina;Sherazi, Andleeb;Narh, Joshua Tetteh;Khattar, Pallavi;Bedi, Puneet
10.1159/000511160
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Acute Kidney Injury in COVID-19 Patients: An Inner City Hospital Experience and Policy Implications. [Abstract]: BACKGROUND: Although diffuse alveolar damage and respiratory failure are the key features of coronavirus disease 2019 (COVID-19), the involvement of other organs such as the kidney has also been rep...
32,576,712
Aging (Albany NY)
ADL-dependency, D-Dimers, LDH and absence of anticoagulation are independently associated with one-month mortality in older inpatients with Covid-19.
BACKGROUND: To assess factors associated with one-month mortality among older inpatients with Covid-19. RESULTS: The mean age was 78 +/- 7.8 years, 55.5% were men, CT scan lung damage was observed in 76% of the patients (mild 23%, moderate 38%, extensive 22%, and severe 7%). The mortality rate was 26%. Dependency/Activ...
covid-19;anticoagulation;geriatric assessment;mortality;predictive biomarkers
Journal Article
Bousquet, Guilhem;Falgarone, Geraldine;Deutsch, David;Derolez, Sophie;Lopez-Sublet, Marilucy;Goudot, Francois-Xavier;Amari, Khadaoudj;Uzunhan, Yurdagul;Bouchaud, Olivier;Pamoukdjian, Frederic
10.18632/aging.103583
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: ADL-dependency, D-Dimers, LDH and absence of anticoagulation are independently associated with one-month mortality in older inpatients with Covid-19. [Abstract]: BACKGROUND: To assess factors associated with one-month mortality among older inpatients with Covid-19. RESULTS: The mean age was 78 +/- 7.8 years, 5...
33,023,910
J Clin Microbiol
When Should Asymptomatic Persons Be Tested for COVID-19?
On 24 August 2020, the Centers for Disease Control and Prevention (CDC) updated its website to highlight that asymptomatic individuals, even those with exposure to a COVID-19-positive contact, do not necessarily need to be tested unless they have medical conditions associated with increased risk of severe illness from ...
covid-19;sars-cov-2;asymptomatic testing;contact tracing;surveillance
Editorial
Schuetz, Audrey N;Hemarajata, Peera;Mehta, Ninad;Campbell, Sheldon;Mitchell, Stephanie;Palavecino, Elizabeth;Butler-Wu, Susan;Miller, Melissa B
10.1128/JCM.02563-20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: When Should Asymptomatic Persons Be Tested for COVID-19? [Abstract]: On 24 August 2020, the Centers for Disease Control and Prevention (CDC) updated its website to highlight that asymptomatic individuals, even those with exposure to a COVID-19-positive contact, do not necessarily need to be tested unless they ...
32,790,664
MMWR Morb Mortal Wkly Rep
Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1-July 25, 2020.
Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1-July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19-Associated Hospitalizat...
Journal Article
Kim, Lindsay;Whitaker, Michael;O'Halloran, Alissa;Kambhampati, Anita;Chai, Shua J;Reingold, Arthur;Armistead, Isaac;Kawasaki, Breanna;Meek, James;Yousey-Hindes, Kimberly;Anderson, Evan J;Openo, Kyle P;Weigel, Andy;Ryan, Patricia;Monroe, Maya L;Fox, Kimberly;Kim, Sue;Lynfield, Ruth;Bye, Erica;Shrum Davis, Sarah;Smelser,...
10.15585/mmwr.mm6932e3
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1-July 25, 2020. [Abstract]: Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is kn...
32,471,829
mBio
Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis of SARS-CoV-2-Related Viruses.
A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was recently identified as the causative agent for the coronavirus disease 2019 (COVID-19) outbreak that has generated a global health crisis. We use a combination of genomic analysis and sensitive profile-based sequence and structure an...
covid-19;orf8;sars;coronavirus;evolution;immune evasion;immunoglobulin;pathogenesis
Comparative Study;Journal Article;Research Support, N.I.H., Intramural;Research Support, Non-U.S. Gov't
Tan, Yongjun;Schneider, Theresa;Leong, Matthew;Aravind, L;Zhang, Dapeng
10.1128/mBio.00760-20
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis of SARS-CoV-2-Related Viruses. [Abstract]: A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was recently identified as the causative agent for the coronavirus disease 2019 (COVID-19) outbreak...
32,656,172
Front Pediatr
Children Infected With SARS-CoV-2 From Family Clusters.
Background: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is ongoing globally. Limited data are available for children with SARS-CoV-2 infection. Methods: A retrospective case study was conducted in one designated hospital for children with SARS-CoV-2 infection in Wuhan. Results: Out of t...
covid-19;sars-cov-2;children;family clusters;viral pneumonia
Journal Article
Sun, Dan;Zhu, Feng;Wang, Cheng;Wu, Jing;Liu, Jie;Chen, Xue;Liu, Zhisheng;Wu, Zubo;Lu, Xiaoxia;Ma, Jiehui;Peng, Hua;Xiao, Han
10.3389/fped.2020.00386
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Children Infected With SARS-CoV-2 From Family Clusters. [Abstract]: Background: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is ongoing globally. Limited data are available for children with SARS-CoV-2 infection. Methods: A retrospective case study was conducted in one designate...
32,129,581
Zhonghua Liu Xing Bing Xue Za Zhi
[Prediction modeling with data fusion and prevention strategy analysis for the COVID-19 outbreak].
Since December 2019, the outbreak of COVID-19 in Wuhan has spread rapidly due to population movement during the Spring Festival holidays. Since January 23rd, 2020, the strategies of containment and contact tracing followed by quarantine and isolation has been implemented extensively in mainland China, and the rates of ...
covid-19;dynamical model;reproductive number
Journal Article
Tang, S Y;Xiao, Y N;Peng, Z H;Shen, H B
10.3760/cma.j.cn112338-20200216-00107
[ 0, 0, 1, 0, 1, 1, 0 ]
[Title]: [Prediction modeling with data fusion and prevention strategy analysis for the COVID-19 outbreak]. [Abstract]: Since December 2019, the outbreak of COVID-19 in Wuhan has spread rapidly due to population movement during the Spring Festival holidays. Since January 23rd, 2020, the strategies of containment and co...
32,257,554
Aging Dis
Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia.
A new study published by the journal Aging & Disease reported that intravenous administration of clinical-grade human mesenchymal stem cells (MSCs) into patients with coronavirus disease 2019 (COVID-19) resulted in improved functional outcomes (Leng et al., Aging Dis, 11:216-228, 2020). This study demonstrated that int...
Editorial
Shetty, Ashok K
10.14336/AD.2020.0301
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia. [Abstract]: A new study published by the journal Aging & Disease reported that intravenous administration of clinical-grade human mesenchymal stem cells (MSCs) into patients with coronavirus disease 2019 (COVI...
33,070,781
BMC Cardiovasc Disord
Cardiology on the cutting edge: updates from the European Society of Cardiology (ESC) Congress 2020.
The 2020 annual Congress of the European Society of Cardiology (ESC) was the first ever to be held virtually. Under the spotlight of 'the cutting edge of cardiology', exciting and ground-breaking cardiovascular (CV) science was presented both in basic and clinical research. This commentary summarizes essential updates ...
atrial fibrillation;covid-19;esc congress;esc guidelines;heart failure;hypertension;myocardial infarction;pulmonary embolism
Editorial
Gallego-Colon, Enrique;Bonaventura, Aldo;Vecchie, Alessandra;Cannata, Antonio;Fitzpatrick, Ciaran Martin
10.1186/s12872-020-01734-4
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Cardiology on the cutting edge: updates from the European Society of Cardiology (ESC) Congress 2020. [Abstract]: The 2020 annual Congress of the European Society of Cardiology (ESC) was the first ever to be held virtually. Under the spotlight of 'the cutting edge of cardiology', exciting and ground-breaking ca...
33,070,544
Rev Cardiovasc Med
Cardiovascular system and COVID-19: manifestations and therapeutics.
The world is currently in the midst of a daunting global pandemic due to SARS-CoV-2 viral infection and associated COVID-19 disease. Healthcare professionals are tasked with the challenge of managing diverse multisystem clinical manifestations of this infection. Although acute hypoxic respiratory failure is the hallmar...
covid-19;coronavirus;arrhythmia;cardiac injury;cardiac therapy;cardiovascular system;heart failure;myocardial infarction;myocarditis;thrombosis
Journal Article;Systematic Review
Mahenthiran, Ajay K;Mahenthiran, Ashorne K;Mahenthiran, Jo
10.31083/j.rcm.2020.03.124
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Cardiovascular system and COVID-19: manifestations and therapeutics. [Abstract]: The world is currently in the midst of a daunting global pandemic due to SARS-CoV-2 viral infection and associated COVID-19 disease. Healthcare professionals are tasked with the challenge of managing diverse multisystem clinical m...
32,715,932
J Biol Dyn
Effects of age-targeted sequestration for COVID-19.
We model the extent to which age-targeted protective sequestration can be used to reduce ICU admissions caused by novel coronavirus COVID-19. Using demographic data from New Zealand, we demonstrate that lowering the age threshold to 50 years of age reduces ICU admissions drastically and show that for sufficiently stric...
covid-19;sir model;age;epidemics;structured population
Journal Article;Research Support, Non-U.S. Gov't
Jamieson-Lane, Alastair;Cytrynbaum, Eric
10.1080/17513758.2020.1795285
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Effects of age-targeted sequestration for COVID-19. [Abstract]: We model the extent to which age-targeted protective sequestration can be used to reduce ICU admissions caused by novel coronavirus COVID-19. Using demographic data from New Zealand, we demonstrate that lowering the age threshold to 50 years of ag...
33,044,091
Curr Med Res Opin
Knowledge of COVID-19 and its prevention among residents of the Gedeo zone, South Ethiopia. Sources of information as a factor.
BACKGROUND: COVID-19 was declared as a pandemic in March 2020. After confirming the first case, the Ethiopian government has been working a lot to prevent transmission. Most of the reported cases were identified from traveling abroad. Effective prevention and control practices depend on awareness and compliance among t...
covid-19;ethiopia;information;knowledge;prevention
Journal Article;Research Support, Non-U.S. Gov't
Aweke, Zemedu;Jemal, Bedru;Mola, Simeneh;Hussen, Robel
10.1080/03007995.2020.1835854
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge of COVID-19 and its prevention among residents of the Gedeo zone, South Ethiopia. Sources of information as a factor. [Abstract]: BACKGROUND: COVID-19 was declared as a pandemic in March 2020. After confirming the first case, the Ethiopian government has been working a lot to prevent transmission. Mo...
32,503,819
In Vivo
Coronavirus Disease (COVID-19): A Machine Learning Bibliometric Analysis.
BACKGROUND/AIM: To evaluate the research trends in coronavirus disease (COVID-19). MATERIALS AND METHODS: A bibliometric analysis was performed using a machine learning bibliometric methodology. Information regarding publication outputs, countries, institutions, journals, keywords, funding and citation counts was retri...
covid-19;bibliometric analysis;coronavirus;machine learning;management
Journal Article;Review
DE Felice, Francesca;Polimeni, Antonella
10.21873/invivo.11951
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease (COVID-19): A Machine Learning Bibliometric Analysis. [Abstract]: BACKGROUND/AIM: To evaluate the research trends in coronavirus disease (COVID-19). MATERIALS AND METHODS: A bibliometric analysis was performed using a machine learning bibliometric methodology. Information regarding publicat...
32,348,711
Palliat Med
Response and role of palliative care during the COVID-19 pandemic: A national telephone survey of hospices in Italy.
BACKGROUND: Palliative care is an important component of health care in pandemics, contributing to symptom control, psychological support, and supporting triage and complex decision making. AIM: To examine preparedness for, and impact of, the COVID-19 pandemic on hospices in Italy to inform the response in other countr...
covid-19;epidemics;health care surveys;hospice care;hospices;palliative care end-of-life care;pandemics;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, Non-U.S. Gov't
Costantini, Massimo;Sleeman, Katherine E;Peruselli, Carlo;Higginson, Irene J
10.1177/0269216320920780
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Response and role of palliative care during the COVID-19 pandemic: A national telephone survey of hospices in Italy. [Abstract]: BACKGROUND: Palliative care is an important component of health care in pandemics, contributing to symptom control, psychological support, and supporting triage and complex decision ...
32,827,582
Biochim Biophys Acta Rev Cancer
COVID-19 and cancer: A guide with suggested COVID-19 rule-out criteria to support clinical decision-making.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious zoonotic pathogen that has exacted heavy public health, social and economic tolls. In February 2020, the World Health Organization acronymed the disease caused by SARS-CoV-2 as COVID-19, for coronavirus disease 2019. The number of confi...
covid-19;cancer;sars-cov-2
Journal Article;Review
Larson, Christopher;Oronsky, Bryan;Goyal, Sharad;Ray, Carolyn;Hedjran, Farah;Hammond, Terese C;Kesari, Santosh;Caroen, Scott;Lybeck, Michelle;Dobalian, Vaughn E;Oronsky, Arnold;Reid, Tony
10.1016/j.bbcan.2020.188412
[ 1, 1, 0, 1, 1, 0, 0 ]
[Title]: COVID-19 and cancer: A guide with suggested COVID-19 rule-out criteria to support clinical decision-making. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious zoonotic pathogen that has exacted heavy public health, social and economic tolls. In February 2020, the Wo...
32,364,920
Heart Surg Forum
A Case of Postoperative Covid-19 Infection After Cardiac Surgery: Lessons Learned.
While the focus of the medical community is on the management of COVID-19 and its associated complex presentations, it is critical to recognize that patients will continue to present with other medical problems that require urgent therapeutic interventions. There is growing concern that such interventions might have an...
covid-19;cardiac surgery policies;scoring system
Journal Article
Rescigno, Giuseppe;Firstenberg, Michael;Rudez, Igor;Uddin, Mauin;Nagarajan, Kumar;Nikolaidis, Nicholas
10.1532/hsf.3011
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of Postoperative Covid-19 Infection After Cardiac Surgery: Lessons Learned. [Abstract]: While the focus of the medical community is on the management of COVID-19 and its associated complex presentations, it is critical to recognize that patients will continue to present with other medical problems that ...
32,294,229
Aust N Z J Obstet Gynaecol
COVID-19 vaginal delivery - A case report.
The novel coronavirus termed SARS-CoV-2 (COVID-19) is a major public health challenge. Many maternity units around the country are currently considering management protocols for these patients. We report a case from a tertiary Australian hospital describing an uncomplicated vaginal birth in a COVID-19 positive mother. ...
covid-19;breastfeeding;coronavirus;neonatal;vaginal delivery
Case Reports;Journal Article
Lowe, Belinda;Bopp, Benjamin
10.1111/ajo.13173
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 vaginal delivery - A case report. [Abstract]: The novel coronavirus termed SARS-CoV-2 (COVID-19) is a major public health challenge. Many maternity units around the country are currently considering management protocols for these patients. We report a case from a tertiary Australian hospital describin...
32,371,558
Cleve Clin J Med
Hydroxychloroquine use in the COVID-19 patient.
Hydroxychloroquine (HCQ) has multiple potential antiviral mechanisms of action that differ according to the pathogen studied (eg, Chikungunya, Dengue virus, human immunodeficiency virus, poliovirus, Zika virus). Data on HCQ for treatment of COVID-19 are rapidly evolving. To date, there is no evidence from randomized co...
Journal Article
Littlejohn, Emily
10.3949/ccjm.87a.ccc011
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine use in the COVID-19 patient. [Abstract]: Hydroxychloroquine (HCQ) has multiple potential antiviral mechanisms of action that differ according to the pathogen studied (eg, Chikungunya, Dengue virus, human immunodeficiency virus, poliovirus, Zika virus). Data on HCQ for treatment of COVID-19 a...
32,580,792
Epidemiol Infect
Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration.
The clinical characteristics of patients with COVID-19 were analysed to determine the factors influencing the prognosis and virus shedding time to facilitate early detection of disease progression. Logistic regression analysis was used to explore the relationships among prognosis, clinical characteristics and laborator...
covid-19;clinical characteristics;duration of viral shedding;influencing factor;prognosis of disease
Journal Article
Han, Jing;Shi, Li-Xia;Xie, Yi;Zhang, Yong-Jin;Huang, Shu-Ping;Li, Jian-Guo;Wang, He-Rong;Shao, Shi-Feng
10.1017/S0950268820001399
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration. [Abstract]: The clinical characteristics of patients with COVID-19 were analysed to determine the factors influencing the prognosis and virus shedding time to facilitate early detection of disease progression. Logisti...
32,930,089
Am J Trop Med Hyg
Stability of SARS-CoV-2 on Produce following a Low-Dose Aerosol Exposure.
We modeled the stability of SARS-CoV-2 on apples, tomatoes, and jalapeno peppers at two temperatures following a low-dose aerosol exposure designed to simulate an airborne transmission event involving droplet nuclei. Infectious virus was not recovered postexposure.
Journal Article
Haddow, Andrew D;Watt, Taylor R;Bloomfield, Holly A;Shamblin, Joshua D;Dyer, David N;Harbourt, David E
10.4269/ajtmh.20-1033
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Stability of SARS-CoV-2 on Produce following a Low-Dose Aerosol Exposure. [Abstract]: We modeled the stability of SARS-CoV-2 on apples, tomatoes, and jalapeno peppers at two temperatures following a low-dose aerosol exposure designed to simulate an airborne transmission event involving droplet nuclei. Infectio...
33,017,479
Headache
Headache in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Narrative Review.
OBJECTIVE: To summarize available literature regarding headache as a manifestation of coronaviruses and to describe potential underlying mechanisms. REVIEW METHODS: References for this review were identified by searches within PubMed without any date restrictions. The search terms used were coronavirus disease 2019 (CO...
coronavirus disease 2019;headache;migraine;severe acute respiratory syndrome coronavirus 2
Journal Article;Review
Tolebeyan, Amir Soheil;Zhang, Niushen;Cooper, Vanessa;Kuruvilla, Deena E
10.1111/head.13980
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Headache in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Narrative Review. [Abstract]: OBJECTIVE: To summarize available literature regarding headache as a manifestation of coronaviruses and to describe potential underlying mechanisms. REVIEW METHODS: References for this review we...
32,591,704
Br Dent J
COVID-19 pandemic: the first wave - an audit and guidance for paediatric dentistry.
With the use of newly issued guidelines, King's College Hospital has developed new standard operating procedures specifically for the COVID-19 pandemic. Given the unprecedented nature of the current global pandemic, this paper highlights how paediatric dental emergencies can be managed safely and efficiently, as well a...
Journal Article
Ilyas, Nabeel;Agel, Mona;Mitchell, Julie;Sood, Sanjeev
10.1038/s41415-020-1702-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic: the first wave - an audit and guidance for paediatric dentistry. [Abstract]: With the use of newly issued guidelines, King's College Hospital has developed new standard operating procedures specifically for the COVID-19 pandemic. Given the unprecedented nature of the current global pandemic,...
32,307,653
Stem Cell Rev Rep
CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement.
The expressive number of deaths and confirmed cases of SARS-CoV-2 call for an urgent demand of effective and available drugs for COVID-19 treatment. CD147, a receptor on host cells, is a novel route for SARS-CoV-2 invasion. Thus, drugs that interfere in the spike protein/CD147 interaction or CD147 expression may inhibi...
anti-viral responses;asthma;basigin;cellular therapy;coronavirus;diabetes mellitus;emmprin;invasion;lung stem cells;sars-cov-2
Journal Article;Review
Ulrich, Henning;Pillat, Micheli M
10.1007/s12015-020-09976-7
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement. [Abstract]: The expressive number of deaths and confirmed cases of SARS-CoV-2 call for an urgent demand of effective and available drugs for COVID-19 treatment. CD147, a receptor on host cells, is a novel rout...
32,736,486
Palliat Med
Learning a palliative care approach during the COVID-19 pandemic: A case study in an Infectious Diseases Unit.
BACKGROUND: Hospital palliative care is an essential part of the COVID-19 response, but relevant data are lacking. The recent literature underscores the need to implement protocols for symptom control and the training of non-specialists by palliative care teams. AIM: The aim of the study was to describe a palliative ca...
coronavirus;case report;education;palliative care;qualitative research
Journal Article
Tanzi, S;Alquati, S;Martucci, G;De Panfilis, L
10.1177/0269216320947289
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Learning a palliative care approach during the COVID-19 pandemic: A case study in an Infectious Diseases Unit. [Abstract]: BACKGROUND: Hospital palliative care is an essential part of the COVID-19 response, but relevant data are lacking. The recent literature underscores the need to implement protocols for sym...
32,436,445
Ther Adv Respir Dis
Potential specific therapies in COVID-19.
COVID-19 has grown into a global pandemic that has strained healthcare throughout the world. There is a sense of urgency in finding a cure for this deadly virus. In this study, we reviewed the empiric options used in common practice for COVID-19, based on the literature available online, with an emphasis on human exper...
il-6;mers;sars-cov-1;convalescent blood products;coronavirus;corticosteroids convalescent sera;favipiravir;interferons;lopinavir-ritonavir;novel virus;remdesivir;ribavirin;tocilizumab
Journal Article;Review
Gul, Muhammad Hamdan;Htun, Zin Mar;Shaukat, Nauman;Imran, Muhammad;Khan, Ahmad
10.1177/1753466620926853
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Potential specific therapies in COVID-19. [Abstract]: COVID-19 has grown into a global pandemic that has strained healthcare throughout the world. There is a sense of urgency in finding a cure for this deadly virus. In this study, we reviewed the empiric options used in common practice for COVID-19, based on t...
32,816,925
BMJ Case Rep
Acute pericarditis as a primary presentation of COVID-19.
The COVID-19 pandemic is a highly contagious viral illness which conventionally manifests primarily with respiratory symptoms. We report a case whose first manifestation of COVID-19 was pericarditis, in the absence of respiratory symptoms, without any serious complications. Cardiac involvement in various forms is possi...
global health;pericardial disease
Case Reports;Journal Article
Kumar, Rajesh;Kumar, Jathinder;Daly, Caroline;Edroos, Sadat Ali
10.1136/bcr-2020-237617
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Acute pericarditis as a primary presentation of COVID-19. [Abstract]: The COVID-19 pandemic is a highly contagious viral illness which conventionally manifests primarily with respiratory symptoms. We report a case whose first manifestation of COVID-19 was pericarditis, in the absence of respiratory symptoms, w...
32,904,501
World Dev
The ABCs of Covid-19 prevention in Malawi: Authority, benefits, and costs of compliance.
A wide array of authorities-from religious leaders to government ministers-call upon citizens to take preventative measures against Covid-19. Which authorities can most effectively gain public compliance, and which measures will the public take up? Moreover, do people comply with authorities out of respect for their le...
authority;compliance;covid-19;health behavior;malawi;sub-saharan africa
Journal Article
Kao, Kristen;Lust, Ellen;Dulani, Boniface;Ferree, Karen E;Harris, Adam S;Metheney, Erica
10.1016/j.worlddev.2020.105167
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The ABCs of Covid-19 prevention in Malawi: Authority, benefits, and costs of compliance. [Abstract]: A wide array of authorities-from religious leaders to government ministers-call upon citizens to take preventative measures against Covid-19. Which authorities can most effectively gain public compliance, and w...
32,779,164
Ginekol Pol
The Polish Society of Gynecologists and Obstetricians statement on surgery in gynecology during the COVID-19 pandemic.
The publication presents recommendations on the performance of surgical procedures in gynecology during the COVID- 19 pandemic. The recommendations were prepared by the Polish Society of Gynecologists and Obstetricians, based on current knowledge of SARS CoV-2. These recommendations contain the latest guidelines of sci...
covid-19;sars-cov-2;gynecology;surgery
Journal Article
Stojko, Rafal;Staniczek, Jakub;Olejek, Anita;Rechberger, Tomasz;Malinowski, Andrzej;Pomorski, Michal;Zimmer, Mariusz
10.5603/GP.a2020.0101
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Polish Society of Gynecologists and Obstetricians statement on surgery in gynecology during the COVID-19 pandemic. [Abstract]: The publication presents recommendations on the performance of surgical procedures in gynecology during the COVID- 19 pandemic. The recommendations were prepared by the Polish Soci...
32,840,109
ACS Chem Neurosci
iPSCs-Derived Platform: A Feasible Tool for Probing the Neurotropism of SARS-CoV-2.
Coronavirus Disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a severe public health problem with a high rate of morbidity and mortality. A mounting number of clinical investigations illustrate that COVID-19 patients suffer from neurologic conditions in ...
sars-cov-2;brain infection;human neural progenitor cell;ipscs;neurosphere;organoid
Journal Article;Research Support, Non-U.S. Gov't;Review
Mao, Xiao-Yuan;Jin, Wei-Lin
10.1021/acschemneuro.0c00512
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: iPSCs-Derived Platform: A Feasible Tool for Probing the Neurotropism of SARS-CoV-2. [Abstract]: Coronavirus Disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a severe public health problem with a high rate of morbidity and mortality. A mounting ...
32,100,877
J Med Virol
Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.
From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) crossed the species barriers to infect humans, causing thousands of infections and hundreds of deaths, respectively. Currently, a novel coronavirus (SARS-CoV-2), which has ...
coronavirus disease 2019 (covid-19);sars-cov-2;sars-cov-2 spike protein (s);angiotensin-converting enzyme 2 (ace2);receptor-binding domain (rbd) of coronavirus
Journal Article;Research Support, Non-U.S. Gov't
Liu, Zhixin;Xiao, Xiao;Wei, Xiuli;Li, Jian;Yang, Jing;Tan, Huabing;Zhu, Jianyong;Zhang, Qiwei;Wu, Jianguo;Liu, Long
10.1002/jmv.25726
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2. [Abstract]: From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) crossed the specie...
32,757,558
Aust J Gen Pract
One medical school's experience of sustaining general practice teaching in the time of COVID-19.
Challenges have been encountered in maintaining the Western Sydney University general practice program but effective strategies have been adopted to manage the impact of COVID-19.
Journal Article
Reath, Jennifer;Tan, Lawrence;Brooks, Miriam;Burges, Jane;Lindsay, Natalie;Lo, Winston;Shakur, Shakif;Trankle, Steven A;Wong, Kam Cheong
10.31128/AJGP-COVID-29
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: One medical school's experience of sustaining general practice teaching in the time of COVID-19. [Abstract]: Challenges have been encountered in maintaining the Western Sydney University general practice program but effective strategies have been adopted to manage the impact of COVID-19. [Keywords]:
32,926,868
J Oral Maxillofac Surg
Masks or N95 Respirators During COVID-19 Pandemic-Which One Should I Wear?
PURPOSE: Coronavirus Disease 2019 (COVID-19) has caused suffering and death around the world. Careful selection of facial protection is paramount for preventing virus spread among healthcare workers and preserving mask and N95 respirator supplies. METHODS: This paper is a comprehensive review of literature written in E...
Journal Article;Review
Zhang, Mingzhu;Emery, Andrew Robert;Tannyhill, R John 3rd;Zheng, Hui;Wang, Jingping
10.1016/j.joms.2020.08.024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Masks or N95 Respirators During COVID-19 Pandemic-Which One Should I Wear? [Abstract]: PURPOSE: Coronavirus Disease 2019 (COVID-19) has caused suffering and death around the world. Careful selection of facial protection is paramount for preventing virus spread among healthcare workers and preserving mask and N...
32,805,623
Thromb Res
Anti Xa activity after high dose LMWH thrombosis prophylaxis in covid 19 patients at the intensive care unit.
INTRODUCTION: Coagulopathy in Coronavirus disease 2019 (covid-19) has been demonstrated by an increase in D-dimer, prothrombin time (PT), fibrinogen and factor VIII. Venous thromboembolic events are a common abnormality in patients with covid-19. We evaluate the results of intensive care unit (ICU) thrombosis prophylax...
anti xa activity;covid-19;thrombosis prophylaxis management;viscoelastic coagulation tests
Letter;Comment
Vlot, E A;Van den Dool, E J;Hackeng, C M;Sohne, M;Noordzij, P G;Van Dongen, E P A
10.1016/j.thromres.2020.07.035
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Anti Xa activity after high dose LMWH thrombosis prophylaxis in covid 19 patients at the intensive care unit. [Abstract]: INTRODUCTION: Coagulopathy in Coronavirus disease 2019 (covid-19) has been demonstrated by an increase in D-dimer, prothrombin time (PT), fibrinogen and factor VIII. Venous thromboembolic e...
32,788,164
BMJ Evid Based Med
Is there a smoker's paradox in COVID-19?
Although it is well established that cigarette smoking is associated with morbidity and mortality in several respiratory infections, data from recent studies suggest that active smokers are underrepresented among patients with COVID-19. This has led to claims that a 'smoker's paradox' may exist in COVID-19, wherein smo...
covid-19;coronavirus disease 2019;nicotine;outcomes;smoking;tobacco
Journal Article
Usman, Muhammad Shariq;Siddiqi, Tariq Jamal;Khan, Muhammad Shahzeb;Patel, Urvish K;Shahid, Izza;Ahmed, Jawad;Kalra, Ankur;Michos, Erin D
10.1136/bmjebm-2020-111492
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Is there a smoker's paradox in COVID-19? [Abstract]: Although it is well established that cigarette smoking is associated with morbidity and mortality in several respiratory infections, data from recent studies suggest that active smokers are underrepresented among patients with COVID-19. This has led to claim...
32,851,910
J Biomol Struct Dyn
Insights into the structural and dynamical changes of spike glycoprotein mutations associated with SARS-CoV-2 host receptor binding.
Novel Coronavirus or SARS-CoV-2 has received worldwide attention due to the COVID-19 pandemic, which originated in Wuhan, China leading to thousands of deaths to date. The SARS-CoV-2 Spike glycoprotein protein is one of the main focus of COVID-19 related research as it is a structural protein that facilitates its attac...
covid-19;md simulations;rbd and hr1 domain;sars-cov-2 spike glycoprotein;deleterious mutations
Journal Article
Ahamad, Shahzaib;Kanipakam, Hema;Gupta, Dinesh
10.1080/07391102.2020.1811774
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Insights into the structural and dynamical changes of spike glycoprotein mutations associated with SARS-CoV-2 host receptor binding. [Abstract]: Novel Coronavirus or SARS-CoV-2 has received worldwide attention due to the COVID-19 pandemic, which originated in Wuhan, China leading to thousands of deaths to date...
32,762,516
Hum Vaccin Immunother
Are BCG-induced non-specific effects adequate to provide protection against COVID-19?
The world is experiencing a pandemic of Coronavirus Disease (COVID-19) caused by type-2 Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Vaccination is the only option to prevent future surges of the disease. Efforts for developing an effective vaccine are underway, but the timeline for the widespread availa...
bacillus calmette-guerin (bcg) vaccine;coronavirus disease;sars-cov-2;nonspecific effects;trained innate immunity
Journal Article
Vashishtha, Vipin M
10.1080/21645515.2020.1794219
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Are BCG-induced non-specific effects adequate to provide protection against COVID-19? [Abstract]: The world is experiencing a pandemic of Coronavirus Disease (COVID-19) caused by type-2 Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Vaccination is the only option to prevent future surges of the di...
32,295,658
Disaster Med Public Health Prep
Shelter Hospital: Glimmers of Hope in Treating Coronavirus 2019.
Since the first report of the 2019 novel coronavirus disease (COVID-19) in December 2019 in Wuhan, China, the outbreak of the disease has been continuously evolving. Until March 17, 2020, 185, 178 cases had been confirmed, including 81,134 cases in China and 104,044 cases outside of China. In this comment, we report th...
covid-19;infection control;shelter hospital
Journal Article
Zhou, Feng;Gao, Xuan;Li, Mengwei;Zhang, Ying
10.1017/dmp.2020.105
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Shelter Hospital: Glimmers of Hope in Treating Coronavirus 2019. [Abstract]: Since the first report of the 2019 novel coronavirus disease (COVID-19) in December 2019 in Wuhan, China, the outbreak of the disease has been continuously evolving. Until March 17, 2020, 185, 178 cases had been confirmed, including 8...
32,802,589
Innov Clin Neurosci
Telepsychiatry in Psychotherapy Practice.
Psychiatry is one of the first medical specialties to move to the practice of telehealth. Social distancing in the time of COVID-19 has prompted many face-to-face practices, including psychotherapy, to transition to virtual formats. Patients and physicians may have reservations about the change in approach and may have...
coronavirus psychotherapy;telehealth;telepsychiatry for psychotherapy
Journal Article;Review
Cowan, Allison;Johnson, Racheal;Close, Henrik
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telepsychiatry in Psychotherapy Practice. [Abstract]: Psychiatry is one of the first medical specialties to move to the practice of telehealth. Social distancing in the time of COVID-19 has prompted many face-to-face practices, including psychotherapy, to transition to virtual formats. Patients and physicians ...
32,527,802
Sci Immunol
The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that first emerged in late 2019 is responsible for a pandemic of severe respiratory illness. People infected with this highly contagious virus can present with clinically inapparent, mild, or severe disease. Currently, the virus infection in individuals a...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Premkumar, Lakshmanane;Segovia-Chumbez, Bruno;Jadi, Ramesh;Martinez, David R;Raut, Rajendra;Markmann, Alena;Cornaby, Caleb;Bartelt, Luther;Weiss, Susan;Park, Yara;Edwards, Caitlin E;Weimer, Eric;Scherer, Erin M;Rouphael, Nadine;Edupuganti, Srilatha;Weiskopf, Daniela;Tse, Longping V;Hou, Yixuan J;Margolis, David;Sette, ...
10.1126/sciimmunol.abc8413
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that first emerged in late 2019 is responsible for a pandemic of severe respiratory illness. ...
33,076,856
BMC Infect Dis
Continuous thrombocytopenia after SARS-CoV-2 nucleic acid negative in a non-severe COVID-19 patient for several months.
BACKGROUND: Thrombocytopenia was common in the coronavirus disease (Covid-19) patients during the infection, especially in severe COVID-19 patients, but was less in the non-severe Covid-19 patients. However, the platelet count would be restored after antivirus treatment. In this paper, we report continuous thrombocytop...
continuous thrombocytopenia;non-severe covid-19;sars-cov-2
Case Reports;Journal Article
Wu, Xia;Luo, Dongxia;Liu, Yaling;Zeng, Yilan;Gong, Yuping
10.1186/s12879-020-05495-5
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Continuous thrombocytopenia after SARS-CoV-2 nucleic acid negative in a non-severe COVID-19 patient for several months. [Abstract]: BACKGROUND: Thrombocytopenia was common in the coronavirus disease (Covid-19) patients during the infection, especially in severe COVID-19 patients, but was less in the non-severe...
33,019,935
Curr Rheumatol Rev
COVID-19: a Great Mime or a Trigger Event of Autoimmune Manifestations?
Viruses can induce autoimmune diseases, in addition to genetic predisposition and environmental factors. Particularly, coronaviruses are mentioned among the viruses implicated in autoimmunity. Today, the world's greatest threat derives from the pandemic of a new human coronavirus, called "severe acute respiratory syndr...
covid-19;antiphospholipid antibodies;autoimmune manifestations;endothelium;pathogenesis;regulatory t cells;thrombosis;vasculitis.
Journal Article
Fatone, Maria Celeste
10.2174/1573397116666201005122603
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19: a Great Mime or a Trigger Event of Autoimmune Manifestations? [Abstract]: Viruses can induce autoimmune diseases, in addition to genetic predisposition and environmental factors. Particularly, coronaviruses are mentioned among the viruses implicated in autoimmunity. Today, the world's greatest threat...
32,652,521
J Pediatric Infect Dis Soc
Clinical Characteristics and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italian Pediatric Oncology Patients: A Study From the Infectious Diseases Working Group of the Associazione Italiana di Oncologia e Ematologia Pediatrica.
BACKGROUND: Little is known as yet about the outcome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children being treated for cancer. METHODS: We collected information on the clinical characteristics and outcomes of a cohort of 29 children (16 female and 13 male; median age, 7 years [rang...
covid-19 epidemic;sars-cov-2 infection;outcome;pediatric malignancy
Journal Article
Bisogno, Gianni;Provenzi, Massimo;Zama, Daniele;Tondo, Annalisa;Meazza, Cristina;Colombini, Antonella;Galaverna, Federica;Compagno, Francesca;Carraro, Francesca;De Santis, Raffaela;Meneghello, Linda;Baretta, Valentina;Cesaro, Simone
10.1093/jpids/piaa088
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italian Pediatric Oncology Patients: A Study From the Infectious Diseases Working Group of the Associazione Italiana di Oncologia e Ematologia Pediatrica. [Abstract]: BACKGROUND: Little is known as yet about th...
32,516,204
Am J Gastroenterol
Gastrointestinal Bleeding in Patients with Severe SARS-CoV-2.
Gastrointestinal symptoms are common and frequently reported in Coronavirus Disease-2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is unclear if SARS-CoV-2 is associated with increased risk of gastrointestinal bleeding (GIB). Nevertheless, GIB in COVID-19 patients p...
Case Reports;Journal Article
Gadiparthi, Chiranjeevi;Perisetti, Abhilash;Sayana, Hari;Tharian, Benjamin;Inamdar, Sumant;Korman, Andrew
10.14309/ajg.0000000000000719
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Gastrointestinal Bleeding in Patients with Severe SARS-CoV-2. [Abstract]: Gastrointestinal symptoms are common and frequently reported in Coronavirus Disease-2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is unclear if SARS-CoV-2 is associated with increase...
32,473,905
Diabetes Metab Syndr
Challenges of diabetes care management in developing countries with a high incidence of COVID-19: A brief report.
BACKGROUND AND AIMS: Diabetes mellitus (DM) is one of the most critical risk factors for complications and death in COVID-19 patients. The present study aims to highlight challenges in the management of diabetic patients during the COVID-19 outbreak in developing countries. METHODS: We reviewed the literature to obtain...
covid-19;challenges;developing countries;diabetes care;management
Journal Article;Review
Nouhjah, Sedigheh;Jahanfar, Shayesteh
10.1016/j.dsx.2020.05.012
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Challenges of diabetes care management in developing countries with a high incidence of COVID-19: A brief report. [Abstract]: BACKGROUND AND AIMS: Diabetes mellitus (DM) is one of the most critical risk factors for complications and death in COVID-19 patients. The present study aims to highlight challenges in ...
32,716,618
Strengthening health systems resilience: Key concepts and strategies
Strengthening health systems resilience: Key concepts and strategies
Health system resilience is key to coping with catastrophic events, such as the economic crisis and the coronavirus (COVID-19) pandemic, but there is much confusion about what resilience means, how to strengthen it and how to assess it. For operational and assessment purposes, and to foster a more consistent understand...
efficiency, organizational - economics;health management and planning;health policy;health systems plans - organization and administration;strategic planning
Review;Book
Thomas, Steve;Sagan, Anna;Larkin, James;Cylus, Jonathan;Figueras, Josep;Karanikolos, Marina
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Strengthening health systems resilience: Key concepts and strategies [Abstract]: Health system resilience is key to coping with catastrophic events, such as the economic crisis and the coronavirus (COVID-19) pandemic, but there is much confusion about what resilience means, how to strengthen it and how to asse...
32,882,666
J Clin Virol
SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients.
BACKGROUND: The involvement of SARS-CoV-2 antibodies in mediating immunopathogenetic events in COVID-19 patients has been suggested. By using several experimental approaches, we investigated the potential association between SARS-CoV-2 IgGs recognizing the spike (S) protein receptor-binding domain (RBD), neutralizing a...
covid-19;inflammatory biomarkers;neutralizing antibodies;sars-cov-2
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Gozalbo-Rovira, Roberto;Gimenez, Estela;Latorre, Victor;Frances-Gomez, Clara;Albert, Eliseo;Buesa, Javier;Marina, Alberto;Blasco, Maria Luisa;Signes-Costa, Jaime;Rodriguez-Diaz, Jesus;Geller, Ron;Navarro, David
10.1016/j.jcv.2020.104611
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients. [Abstract]: BACKGROUND: The involvement of SARS-CoV-2 antibodies in mediating immunopathogenetic events in COVID-19 patients has been suggested. By using several experimental approaches, we investigate...
32,989,425
Contemp Clin Trials Commun
Health Outcome Predictive Evaluation for COVID 19 international registry (HOPE COVID-19), rationale and design.
The disease produced by the new coronavirus known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), named COVID-19 (Coronavirus Disease-2019) has recently been classified as a pandemic by the World Health Organization (WHO). However, scarce clinical data is available and generally limited to the Chinese ...
covid-19;mortality;prognosis;registry;score
Journal Article
Nunez-Gil, Ivan J;Estrada, Vicente;Fernandez-Perez, Cristina;Feltes, Gisela;Vedia, Oscar;Vergara-Uzcategui, Carlos E;Moreno-Menguia, Victor H;Cerrato, Enrico;D'Ascenzo, Fabrizio;Raposeiras-Roubin, Sergio;Martin-Sanchez, F Javier;Alfonso-Rodriguez, Emilio;Huang, Jia;Ramakrishna, Harish;Gil-Higes, Emma;Fernandez-Ortiz, A...
10.1016/j.conctc.2020.100654
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Health Outcome Predictive Evaluation for COVID 19 international registry (HOPE COVID-19), rationale and design. [Abstract]: The disease produced by the new coronavirus known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), named COVID-19 (Coronavirus Disease-2019) has recently been classified a...
32,574,304
Front Public Health
Health and Economy in COVID-19 Era: A Plan for Reconstituting Long-Term Economic Security.
COVID-19 is a rapidly evolving pandemic, which represents a multifaceted global threat. Given the economic consequences, most researchers agree that social distancing measures are an effective strategy relative to the cost. Previous studies indicate that community size as well as viral population risk groups should be ...
covid-19;economy;health;immunity;pandemic
Journal Article
Allen, Mary Beth;Mirsaeidi, Mehdi
10.3389/fpubh.2020.00235
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Health and Economy in COVID-19 Era: A Plan for Reconstituting Long-Term Economic Security. [Abstract]: COVID-19 is a rapidly evolving pandemic, which represents a multifaceted global threat. Given the economic consequences, most researchers agree that social distancing measures are an effective strategy relati...
32,650,523
Cancers (Basel)
Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe.
We describe the outcomes in cancer patients during the initial outbreak of the COVID-19 in Europe from the retrospective, multi-center observational OnCovid study. We identified 204 cancer patients from eight centers in the United Kingdom, Italy, and Spain aged > 18 (mean = 69) and diagnosed with COVID-19 between Febru...
covid-19;sars-cov-2;cancer;coronavirus;mortality;outcomes;survival
Journal Article
Pinato, David J;Lee, Alvin J X;Biello, Federica;Segui, Elia;Aguilar-Company, Juan;Carbo, Anna;Bruna, Riccardo;Bower, Mark;Rizzo, Gianpiero;Benafif, Sarah;Carmona, Carme;Chopra, Neha;Cruz, Claudia Andrea;D'Avanzo, Francesca;Evans, Joanne S;Galazi, Myria;Garcia-Fructuoso, Isabel;Dalla Pria, Alessia;Newsom-Davis, Thomas;O...
10.3390/cancers12071841
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe. [Abstract]: We describe the outcomes in cancer patients during the initial outbreak of the COVID-19 in Europe from the retrospective, multi-center observational OnCo...
32,725,449
Neurol Sci
Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients.
Respiratory viruses are opportunistic pathogens that infect the upper respiratory tract in humans and cause severe illnesses, especially in vulnerable populations. Some viruses have neuroinvasive properties and activate the immune response in the brain. These immune events may be neuroprotective or they may cause long-...
acute and chronic neurological diseases;cns infection;covid-19;encephalitis;encephalopathy;human coronavirus;human respiratory virus;neuroinvasion;respiratory viral infection
Journal Article;Review
Yachou, Yassine;El Idrissi, Abdeslem;Belapasov, Vladimir;Ait Benali, Said
10.1007/s10072-020-04575-3
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients. [Abstract]: Respiratory viruses are opportunistic pathogens that infect the upper respiratory tract in humans and cause severe illnesses, especially in vulnerable populati...
32,909,955
JMIR Public Health Surveill
An Online Influenza Surveillance System for Primary Care Workers in Switzerland: Observational Prospective Pilot Study.
BACKGROUND: A better understanding of the influenza epidemiology among primary care workers could guide future recommendations to prevent transmission in primary care practices. Therefore, we designed a pilot study to assess the feasibility of using a work-based online influenza surveillance system among primary care w...
influenza;nosocomial;online;primary care;surveillance system;transmission
Journal Article;Observational Study
Martin, Sebastien;Maeder, Muriel Nirina;Goncalves, Ana Rita;Pedrazzini, Baptiste;Perdrix, Jean;Rochat, Carine;Senn, Nicolas;Mueller, Yolanda
10.2196/17242
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: An Online Influenza Surveillance System for Primary Care Workers in Switzerland: Observational Prospective Pilot Study. [Abstract]: BACKGROUND: A better understanding of the influenza epidemiology among primary care workers could guide future recommendations to prevent transmission in primary care practices. T...
32,890,313
Shock
Critically ILL COVID-19 Patients With Acute Kidney Injury Have Reduced Renal Blood Flow and Perfusion Despite Preserved Cardiac Function; A Case-Control Study Using Contrast Enhanced Ultrasound.
BACKGROUND: Acute Kidney Injury (AKI) is a common complication of COVID-19 critical illness but the pathophysiology is uncertain. Some evidence has indicated that a vascular aetiology may be implicated. We used contrast enhanced ultrasound (CEUS) and echocardiography to study renal perfusion and global blood flow and c...
Journal Article;Research Support, Non-U.S. Gov't
Watchorn, James;Huang, Dean Y;Joslin, Jennifer;Bramham, Kate;Hutchings, Sam D
10.1097/SHK.0000000000001659
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Critically ILL COVID-19 Patients With Acute Kidney Injury Have Reduced Renal Blood Flow and Perfusion Despite Preserved Cardiac Function; A Case-Control Study Using Contrast Enhanced Ultrasound. [Abstract]: BACKGROUND: Acute Kidney Injury (AKI) is a common complication of COVID-19 critical illness but the path...
32,947,047
Contemp Clin Trials
Semiparametric Bayesian inference for the transmission dynamics of COVID-19 with a state-space model.
The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and the effects of mitigation policies. We develop a novel Bayesian approach to such ...
effective reproduction number;forecasting;gaussian process;infectious disease;parallel tempering;sir model
Journal Article
Zhou, Tianjian;Ji, Yuan
10.1016/j.cct.2020.106146
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Semiparametric Bayesian inference for the transmission dynamics of COVID-19 with a state-space model. [Abstract]: The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insi...
32,191,588
Radiology
Using Artificial Intelligence to Detect COVID-19 and Community-acquired Pneumonia Based on Pulmonary CT: Evaluation of the Diagnostic Accuracy.
Background Coronavirus disease 2019 (COVID-19) has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and accurate detection of COVID-19 using chest CT. Purpose To develop a fully automatic framework to detect COVID-19 using chest CT and evaluate its performance. Material...
Evaluation Study;Journal Article;Multicenter Study
Li, Lin;Qin, Lixin;Xu, Zeguo;Yin, Youbing;Wang, Xin;Kong, Bin;Bai, Junjie;Lu, Yi;Fang, Zhenghan;Song, Qi;Cao, Kunlin;Liu, Daliang;Wang, Guisheng;Xu, Qizhong;Fang, Xisheng;Zhang, Shiqin;Xia, Juan;Xia, Jun
10.1148/radiol.2020200905
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Using Artificial Intelligence to Detect COVID-19 and Community-acquired Pneumonia Based on Pulmonary CT: Evaluation of the Diagnostic Accuracy. [Abstract]: Background Coronavirus disease 2019 (COVID-19) has widely spread all over the world since the beginning of 2020. It is desirable to develop automatic and a...
33,007,143
Br J Health Psychol
Reasoned action approach and compliance with recommended behaviours to prevent the transmission of the SARS-CoV-2 virus in the UK.
OBJECTIVES: To examine associations between demographics, people's beliefs, and compliance with behaviours recommended by the UK government to prevent the transmission of the SARS-CoV-2 virus that causes COVID-19. DESIGN: A two-wave online survey conducted one week apart during the national lockdown (April, 2020). MEAS...
covid-19;behaviour;compliance;coronavirus;prevention;reasoned action approach;theory of planned behaviour
Journal Article;Research Support, Non-U.S. Gov't
Norman, Paul;Wilding, Sarah;Conner, Mark
10.1111/bjhp.12474
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reasoned action approach and compliance with recommended behaviours to prevent the transmission of the SARS-CoV-2 virus in the UK. [Abstract]: OBJECTIVES: To examine associations between demographics, people's beliefs, and compliance with behaviours recommended by the UK government to prevent the transmission ...
32,441,548
J Am Heart Assoc
Unpredictable Fall of Severe Emergent Cardiovascular Diseases Hospital Admissions During the COVID-19 Pandemic: Experience of a Single Large Center in Northern Italy.
Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS-CoV 2 pandemic related is largely unknown. The aim of this study was to analyze the e...
covid-19;acute coronary syndromes;cardiology;emergent cardiovascular diseases;pacemaker
Comparative Study;Journal Article
Toniolo, Mauro;Negri, Francesco;Antonutti, Marco;Mase, Marco;Facchin, Domenico
10.1161/JAHA.120.017122
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Unpredictable Fall of Severe Emergent Cardiovascular Diseases Hospital Admissions During the COVID-19 Pandemic: Experience of a Single Large Center in Northern Italy. [Abstract]: Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europ...
32,653,662
Clin Microbiol Infect
Virus shedding dynamics in asymptomatic and mildly symptomatic patients infected with SARS-CoV-2.
OBJECTIVES: Asymptomatic patients, together with those with mild symptoms of coronavirus disease 2019 (COVID-19), may play an important role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. However, the dynamics of virus shedding during the various phases of the clinical course of COVID-19 ...
antibodies;asymptomatic infections;convalescence;sars-cov-2;virus shedding
Journal Article
Li, W;Su, Y-Y;Zhi, S-S;Huang, J;Zhuang, C-L;Bai, W-Z;Wan, Y;Meng, X-R;Zhang, L;Zhou, Y-B;Luo, Y-Y;Ge, S-X;Chen, Y-K;Ma, Y
10.1016/j.cmi.2020.07.008
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Virus shedding dynamics in asymptomatic and mildly symptomatic patients infected with SARS-CoV-2. [Abstract]: OBJECTIVES: Asymptomatic patients, together with those with mild symptoms of coronavirus disease 2019 (COVID-19), may play an important role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
32,862,137
Pract Neurol
Video consultations in ordinary and extraordinary times.
Tele-neurology is a neurological consultation at a distance, or not in person, using various technologies to achieve connectivity, including the telephone and the internet. The telephone is ubiquitous and is a standard part of how we manage patients. Video consulting has been used for a long time in some centres, parti...
clinical neurology;headache
Journal Article
Duncan, Callum;Macleod, Angus D
10.1136/practneurol-2020-002579
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Video consultations in ordinary and extraordinary times. [Abstract]: Tele-neurology is a neurological consultation at a distance, or not in person, using various technologies to achieve connectivity, including the telephone and the internet. The telephone is ubiquitous and is a standard part of how we manage p...
32,641,296
Antimicrob Agents Chemother
Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations.
Coronavirus disease 2019 (COVID-19) leads to inflammatory cytokine release, which can downregulate the expression of metabolizing enzymes. This cascade affects drug concentrations in the plasma. We investigated the association between lopinavir (LPV) and hydroxychloroquine (HCQ) plasma concentrations and the levels of ...
covid-19;hydroxychloroquine;inflammation;levels;lopinavir-ritonavir
Journal Article;Research Support, Non-U.S. Gov't
Marzolini, Catia;Stader, Felix;Stoeckle, Marcel;Franzeck, Fabian;Egli, Adrian;Bassetti, Stefano;Hollinger, Alexa;Osthoff, Michael;Weisser, Maja;Gebhard, Caroline E;Baettig, Veronika;Geenen, Julia;Khanna, Nina;Tschudin-Sutter, Sarah;Mueller, Daniel;Hirsch, Hans H;Battegay, Manuel;Sendi, Parham
10.1128/AAC.01177-20
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations. [Abstract]: Coronavirus disease 2019 (COVID-19) leads to inflammatory cytokine release, which can downregulate the expression of metabolizing enzymes. This cascade affects drug concentrations in th...
32,426,001
Reumatol Clin
[Colchicine: a potential therapeutic tool against COVID-19. Experience of 5 patients].
COVID-19 is a newly emerged disease that has become a global public health challenge. Due to a lack of knowledge about the virus, a significant number of potential targets for using a particular drug have been proposed. Five cases with a clinical history of biopolymers in the gluteal region that developed iatrogenic al...
ards;covid-19;colchicine;inflammasome;sars-cov-2
English Abstract;Journal Article
Montealegre-Gomez, Giovanni;Garavito, Edgar;Gomez-Lopez, Arley;Rojas-Villarraga, Adriana;Parra-Medina, Rafael
10.1016/j.reuma.2020.05.001
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Colchicine: a potential therapeutic tool against COVID-19. Experience of 5 patients]. [Abstract]: COVID-19 is a newly emerged disease that has become a global public health challenge. Due to a lack of knowledge about the virus, a significant number of potential targets for using a particular drug have been pr...
32,410,412
Korean J Radiol
Association between Initial Chest CT or Clinical Features and Clinical Course in Patients with Coronavirus Disease 2019 Pneumonia.
OBJECTIVE: To identify the initial chest computed tomography (CT) findings and clinical characteristics associated with the course of coronavirus disease 2019 (COVID-19) pneumonia. MATERIALS AND METHODS: Baseline CT scans and clinical and laboratory data of 72 patients admitted with COVID-19 pneumonia (39 men, 46.2 +/-...
2019-ncov;admission;covid-19;ct;clinical course;computed tomography;coronavirus;discharge;hospital stay;hospitalization;outcome;pneumonia;prediction;prognosis;recovery
Journal Article;Research Support, Non-U.S. Gov't
Liu, Zhe;Jin, Chao;Wu, Carol C;Liang, Ting;Zhao, Huifang;Wang, Yan;Wang, Zekun;Li, Fen;Zhou, Jie;Cai, Shubo;Zeng, Lingxia;Yang, Jian
10.3348/kjr.2020.0171
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Association between Initial Chest CT or Clinical Features and Clinical Course in Patients with Coronavirus Disease 2019 Pneumonia. [Abstract]: OBJECTIVE: To identify the initial chest computed tomography (CT) findings and clinical characteristics associated with the course of coronavirus disease 2019 (COVID-19...
32,461,326
CMAJ
Baseline characteristics and outcomes of patients with COVID-19 admitted to intensive care units in Vancouver, Canada: a case series.
BACKGROUND: Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with high intensive care unit (ICU) mortality. We aimed to describe the clinical characteristics and outcomes of critically ill patients with coronavirus disease 2019 (COVID-19) in a Canadian setting. METHODS: We conducted a...
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Mitra, Anish R;Fergusson, Nicholas A;Lloyd-Smith, Elisa;Wormsbecker, Andrew;Foster, Denise;Karpov, Andrei;Crowe, Sarah;Haljan, Greg;Chittock, Dean R;Kanji, Hussein D;Sekhon, Mypinder S;Griesdale, Donald E G
10.1503/cmaj.200794
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Baseline characteristics and outcomes of patients with COVID-19 admitted to intensive care units in Vancouver, Canada: a case series. [Abstract]: BACKGROUND: Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with high intensive care unit (ICU) mortality. We aimed to describe t...
32,741,085
Clin Otolaryngol
Is loss of sense of smell a diagnostic marker in COVID-19: A systematic review and meta-analysis.
AIMS: To systematically review the currently available evidence investigating the association between olfactory dysfunction (OD) and the novel coronavirus (COVID-19). To analyse the prevalence of OD in patients who have tested positive on polymerase chain reaction (PCR) for COVID-19. To perform a meta-analysis of patie...
2019 novel coronavirus disease;anosmia;covid-19;sars coronavirus;sars virus;olfaction disorders;smell
Journal Article;Meta-Analysis;Systematic Review
Rocke, John;Hopkins, Claire;Philpott, Carl;Kumar, Nirmal
10.1111/coa.13620
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Is loss of sense of smell a diagnostic marker in COVID-19: A systematic review and meta-analysis. [Abstract]: AIMS: To systematically review the currently available evidence investigating the association between olfactory dysfunction (OD) and the novel coronavirus (COVID-19). To analyse the prevalence of OD in...
32,624,494
BMJ Open Respir Res
Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with COVID-19: retrospective analysis from a UK teaching hospital.
Since the outbreak of COVID-19 in China in December 2019, a pandemic has rapidly developed on a scale that has overwhelmed health services in a number of countries. COVID-19 has the potential to lead to severe hypoxia; this is usually the cause of death if it occurs. In a substantial number of patients, adequate arteri...
assisted ventilation;lung physiology;non invasive ventilation;respiratory infection;viral infection
Journal Article
Burns, Graham P;Lane, Nicholas D;Tedd, Hilary M;Deutsch, Elizabeth;Douglas, Florence;West, Sophie D;Macfarlane, Jim G;Wiscombe, Sarah;Funston, Wendy
10.1136/bmjresp-2020-000621
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with COVID-19: retrospective analysis from a UK teaching hospital. [Abstract]: Since the outbreak of COVID-19 in China in December 2019, a pandemic has rapidly developed on a scale that has ove...