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33,024,705 | Interdiscip Neurosurg | Changes in stroke presentation in neo-Covid patients: A case study. | A 35 year old male had a generalized seizure a week after symptoms of daily fever, rigors, and throat discomfort. He was hospitalized. Magnetic resonance imaging brain showed multiple bilateral scattered infarcts. COVID-19 swab test came positive. An elaborate panel of tests for young strokes, cardiac work-up was norma... | covid-19;cytokine storm;scattered brain infarcts;seizure;stroke | Case Reports | Kohli, Anoop;Gupta, Charchit;Dutta, Shvet;Madaan, Chirag | 10.1016/j.inat.2020.100949 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Changes in stroke presentation in neo-Covid patients: A case study. [Abstract]: A 35 year old male had a generalized seizure a week after symptoms of daily fever, rigors, and throat discomfort. He was hospitalized. Magnetic resonance imaging brain showed multiple bilateral scattered infarcts. COVID-19 swab tes... |
32,395,850 | Drug Alcohol Rev | Assessing the validity of the Australian Treatment Outcomes Profile for telephone administration in drug health treatment populations. | INTRODUCTION AND AIMS: The Australian Treatment Outcomes Profile (ATOP) is a brief clinical tool measuring recent substance use, health and wellbeing among clients attending alcohol and other drug (AOD) treatment services. It has previously been assessed for concurrent validity and inter-rater reliability. In this stud... | health care;outcome assessment;psychometric;substance-related disorder;telemedicine | Journal Article;Research Support, Non-U.S. Gov't;Validation Study | Deacon, Rachel M;Mammen, Kristie;Holmes, Jennifer;Dunlop, Adrian;Bruno, Raimondo;Mills, Llewellyn;Graham, Robert;Lintzeris, Nicholas | 10.1111/dar.13088 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Assessing the validity of the Australian Treatment Outcomes Profile for telephone administration in drug health treatment populations. [Abstract]: INTRODUCTION AND AIMS: The Australian Treatment Outcomes Profile (ATOP) is a brief clinical tool measuring recent substance use, health and wellbeing among clients ... |
32,912,359 | Disaster Med Public Health Prep | Deployment and Operation of Outdoor Treatment Tents During the COVID-19 Pandemic. | The coronavirus disease 2019 (COVID-19) pandemic spread throughout the globe, with an alarming amount of new cases daily. To prepare for the inevitable patient surge, 1 hospital set up outdoor triage tents to assist with increased volume. Using the paradigm of space, staff, and stuff, an outdoor treatment area was desi... | covid-19;emergency preparedness;pandemic;surge capacity;triage tent | Journal Article | Peterson, Keith H J;Muckey, Erin Joy Cavin | 10.1017/dmp.2020.355 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Deployment and Operation of Outdoor Treatment Tents During the COVID-19 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic spread throughout the globe, with an alarming amount of new cases daily. To prepare for the inevitable patient surge, 1 hospital set up outdoor triage tents to assist w... |
32,671,601 | Cardiovasc Drugs Ther | Cardiovascular Complications of COVID-19: Pharmacotherapy Perspective. | Coronavirus disease of 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly the world over. The disease was declared "pandemic" by the World Health Organization. An approved therapy for patients with COVID-19 has yet to emerge; however, there are some me... | covid-19;cardiovascular;drug-drug interactions;pharmacotherapy;sars-cov2;venous thromboembolism | Journal Article;Review | Talasaz, Azita Hajhossein;Kakavand, Hessam;Van Tassell, Benjamin;Aghakouchakzadeh, Maryam;Sadeghipour, Parham;Dunn, Steven;Geraiely, Babak | 10.1007/s10557-020-07037-2 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Cardiovascular Complications of COVID-19: Pharmacotherapy Perspective. [Abstract]: Coronavirus disease of 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly the world over. The disease was declared "pandemic" by the World Health Organization. ... |
32,125,362 | JAMA | Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. | Importance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019 and has spread globally with sustained human-to-human transmission outside China. Objective: To report the initial experience in Singapore with the epidemiologic investigation of this outbreak, clinical fe... | Journal Article;Research Support, Non-U.S. Gov't | Young, Barnaby Edward;Ong, Sean Wei Xiang;Kalimuddin, Shirin;Low, Jenny G;Tan, Seow Yen;Loh, Jiashen;Ng, Oon-Tek;Marimuthu, Kalisvar;Ang, Li Wei;Mak, Tze Minn;Lau, Sok Kiang;Anderson, Danielle E;Chan, Kian Sing;Tan, Thean Yen;Ng, Tong Yong;Cui, Lin;Said, Zubaidah;Kurupatham, Lalitha;Chen, Mark I-Cheng;Chan, Monica;Vaso... | 10.1001/jama.2020.3204 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. [Abstract]: Importance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019 and has spread globally with sustained human-to-human transmission outside China. Objectiv... | |
32,291,112 | Trends Pharmacol Sci | Ongoing Clinical Trials for the Management of the COVID-19 Pandemic. | COVID-19 has rapidly developed into a worldwide pandemic with a significant health and economic burden. There are currently no approved treatments or preventative therapeutic strategies. Hundreds of clinical studies have been registered with the intention of discovering effective treatments. Here, we review currently r... | 2019-ncov;covid-19;sars-cov-2;coronavirus;pandemic | Journal Article;Review | Lythgoe, Mark P;Middleton, Paul | 10.1016/j.tips.2020.03.006 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Ongoing Clinical Trials for the Management of the COVID-19 Pandemic. [Abstract]: COVID-19 has rapidly developed into a worldwide pandemic with a significant health and economic burden. There are currently no approved treatments or preventative therapeutic strategies. Hundreds of clinical studies have been regi... |
32,858,475 | Diabetes Metab Syndr | Self- management of diabetes mellitus during the Covid-19 pandemic: Recommendations for a resource limited setting. | BACKGROUND AND AIMS: The COVID-19 pandemic has challenged both institutional and self-management of diabetes. The ongoing social distancing and lock downs have negatively impacted to access to care and self-management. METHODS: This is a narrative review of diabetes management in a resource limited setting during the o... | diabetes;diabetes-care;diabetes-management;diabetes-self-management;sars-cov-2-virus | Journal Article;Review | Mukona, Doreen Macherera;Zvinavashe, Mathilda | 10.1016/j.dsx.2020.08.022 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Self- management of diabetes mellitus during the Covid-19 pandemic: Recommendations for a resource limited setting. [Abstract]: BACKGROUND AND AIMS: The COVID-19 pandemic has challenged both institutional and self-management of diabetes. The ongoing social distancing and lock downs have negatively impacted to ... |
32,588,589 | Ann Agric Environ Med | Preliminary information on prevention of infections caused by SARS-COV-2 virus in endoscopic laboratories. | INTRODUCTION: On 11 March 2020, the Director-General of the World Health Organization (WHO) announced COVID-19 (Coronavirus Disease 2019) as a global pandemic Currently, no vaccines are available and there is little evidence of the efficacy of potential therapeutic agents. Furthermore, there is presumably no pre-existi... | covid-19;sars-cov-2 infection;endoscopic laboratory | Journal Article;Review | Gruszecka, Jolanta;Filip, Rafal | 10.26444/aaem/122137 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Preliminary information on prevention of infections caused by SARS-COV-2 virus in endoscopic laboratories. [Abstract]: INTRODUCTION: On 11 March 2020, the Director-General of the World Health Organization (WHO) announced COVID-19 (Coronavirus Disease 2019) as a global pandemic Currently, no vaccines are availa... |
32,601,704 | J Infect Dis | Clinical outcomes and immunologic characteristics of Covid-19 in people with HIV. | We performed a retrospective study of Covid-19 in people with HIV (PWH). PWH with Covid-19 demonstrated severe lymphopenia and decreased CD4+ T cell counts. Levels of inflammatory markers, including C-reactive protein, fibrinogen, D-dimer, interleukin-6, interleukin-8, and TNF-alpha were commonly elevated. In all, 19/7... | covid-19;hiv;sars-cov-2;coronavirus;inflammation;people living with hiv | Journal Article;Research Support, N.I.H., Extramural | Ho, Hsi-En;Peluso, Michael J;Margus, Colton;Matias Lopes, Joao Pedro;He, Chen;Gaisa, Michael M;Osorio, Georgina;Aberg, Judith A;Mullen, Michael P | 10.1093/infdis/jiaa380 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical outcomes and immunologic characteristics of Covid-19 in people with HIV. [Abstract]: We performed a retrospective study of Covid-19 in people with HIV (PWH). PWH with Covid-19 demonstrated severe lymphopenia and decreased CD4+ T cell counts. Levels of inflammatory markers, including C-reactive protein... |
32,827,728 | J Allergy Clin Immunol Pract | Pediatric Asthma Health Care Utilization, Viral Testing, and Air Pollution Changes During the COVID-19 Pandemic. | BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic caused dramatic changes in daily routines and health care utilization and delivery patterns in the United States. Understanding the influence of these changes and associated public health interventions on asthma care is important to determine effects on patie... | asthma;covid-19;pollution;respiratory virus;telemedicine | Journal Article;Research Support, N.I.H., Extramural | Taquechel, Kiara;Diwadkar, Avantika R;Sayed, Samir;Dudley, Jesse W;Grundmeier, Robert W;Kenyon, Chen C;Henrickson, Sarah E;Himes, Blanca E;Hill, David A | 10.1016/j.jaip.2020.07.057 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Pediatric Asthma Health Care Utilization, Viral Testing, and Air Pollution Changes During the COVID-19 Pandemic. [Abstract]: BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic caused dramatic changes in daily routines and health care utilization and delivery patterns in the United States. Understandi... |
32,894,364 | Ann Intensive Care | Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICU. | BACKGROUND: Data on the prevalence of bacterial and viral co-infections among patients admitted to the ICU for acute respiratory failure related to SARS-CoV-2 pneumonia are lacking. We aimed to assess the rate of bacterial and viral co-infections, as well as to report the most common micro-organisms involved in patient... | bacteria;covid-19;co-infection;haemophilus influenzae;sars-cov-2;staphylococcus aureus;streptococcus pneumoniae | Journal Article | Contou, Damien;Claudinon, Aurore;Pajot, Olivier;Micaelo, Maite;Longuet Flandre, Pascale;Dubert, Marie;Cally, Radj;Logre, Elsa;Fraisse, Megan;Mentec, Herve;Plantefeve, Gaetan | 10.1186/s13613-020-00736-x | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICU. [Abstract]: BACKGROUND: Data on the prevalence of bacterial and viral co-infections among patients admitted to the ICU for acute respiratory failure related to SARS-CoV-2 pneumonia are lacking. We aimed to ... |
32,609,167 | Cad Saude Publica | Forecasting the rate of cumulative cases of COVID-19 infection in Northeast Brazil: a Boltzmann function-based modeling study. | The COVID-19 death rate in Northeast Brazil is much higher when compared to the national average, demanding a study into the prognosis of the region for planning control measures and preventing the collapse of the health care system. We estimated the potential total cumulative cases of COVID-19 in the region for the ne... | Journal Article | Melo, Gessyca Cavalcante de;Araujo Neto, Renato Americo de;Araujo, Karina Conceicao Gomes Machado de | 10.1590/0102-311X00105720 | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: Forecasting the rate of cumulative cases of COVID-19 infection in Northeast Brazil: a Boltzmann function-based modeling study. [Abstract]: The COVID-19 death rate in Northeast Brazil is much higher when compared to the national average, demanding a study into the prognosis of the region for planning control me... | |
32,425,701 | Dev Cell | Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. | The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show that cigarette smoke causes a dose-dependent upregulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 receptor, in rodent and human lungs. Using single-cell sequencing data, we demonstrate that ACE2 is expressed in a su... | ace2;covid-19;coronavirus;sars-cov-2;inflammation;interferon;lung development;smoking | Journal Article;Research Support, N.I.H., Extramural | Smith, Joan C;Sausville, Erin L;Girish, Vishruth;Yuan, Monet Lou;Vasudevan, Anand;John, Kristen M;Sheltzer, Jason M | 10.1016/j.devcel.2020.05.012 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. [Abstract]: The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show that cigarette smoke causes a dose-dependent upregulation of angiotensin conve... |
32,924,401 | Arch Argent Pediatr | Critically-ill pediatric patients with COVID-19. An update. | The COVID-19 pandemic has grabbed worldwide attention. The different national governments are making an effort to optimize resources and provide effective treatments inasmuch as they are supported by the evidence, at a rate of production in line with the pressing needs. In the field of pediatrics, COVID-19 has a low se... | covid-19;sars-cov-2;critical disease;pediatrics;severe acute respiratory syndrome | Journal Article;Review | Taffarel, Pedro;Jorro Baron, Facundo | 10.5546/aap.2020.eng.e454 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Critically-ill pediatric patients with COVID-19. An update. [Abstract]: The COVID-19 pandemic has grabbed worldwide attention. The different national governments are making an effort to optimize resources and provide effective treatments inasmuch as they are supported by the evidence, at a rate of production i... |
32,750,131 | J Antimicrob Chemother | Drug interactions: a review of the unseen danger of experimental COVID-19 therapies. | As global health services respond to the coronavirus pandemic, many prescribers are turning to experimental drugs. This review aims to assess the risk of drug-drug interactions in the severely ill COVID-19 patient. Experimental therapies were identified by searching ClinicalTrials.gov for 'COVID-19', '2019-nCoV', '2019... | Journal Article;Research Support, Non-U.S. Gov't;Review | Hodge, Catherine;Marra, Fiona;Marzolini, Catia;Boyle, Alison;Gibbons, Sara;Siccardi, Marco;Burger, David;Back, David;Khoo, Saye | 10.1093/jac/dkaa340 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Drug interactions: a review of the unseen danger of experimental COVID-19 therapies. [Abstract]: As global health services respond to the coronavirus pandemic, many prescribers are turning to experimental drugs. This review aims to assess the risk of drug-drug interactions in the severely ill COVID-19 patient.... | |
32,834,596 | Chaos Solitons Fractals | Stationary distribution and extinction of stochastic coronavirus (COVID-19) epidemic model. | Similar to other epidemics, the novel coronavirus (COVID-19) spread very fast and infected almost two hundreds countries around the globe since December 2019. The unique characteristics of the COVID-19 include its ability of faster expansion through freely existed viruses or air molecules in the atmosphere. Assuming th... | covid-19;global stability;real data;stationary distribution;stochastic epidemic model;threshold value | Journal Article | Din, Anwarud;Khan, Amir;Baleanu, Dumitru | 10.1016/j.chaos.2020.110036 | [
0,
0,
1,
0,
1,
1,
0
] | [Title]: Stationary distribution and extinction of stochastic coronavirus (COVID-19) epidemic model. [Abstract]: Similar to other epidemics, the novel coronavirus (COVID-19) spread very fast and infected almost two hundreds countries around the globe since December 2019. The unique characteristics of the COVID-19 inclu... |
32,900,753 | BMJ Case Rep | An unusual course of disease in two patients with COVID-19: pulmonary cavitation. | Two 59-year-old male patients with COVID-19 pneumonia developed pulmonary cavitation with air-fluid level, accompanied by right-sided chest pain several weeks after first onset of symptoms. Considering a possible bacterial abscess formation, both patients were started on antibiotics. No microbiological pathogen was det... | pneumonia (infectious disease);pneumonia (respiratory medicine);radiology | Case Reports;Journal Article | Muheim, Michael;Weber, Fabio Jose;Muggensturm, Patrick;Seiler, Eva | 10.1136/bcr-2020-237967 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: An unusual course of disease in two patients with COVID-19: pulmonary cavitation. [Abstract]: Two 59-year-old male patients with COVID-19 pneumonia developed pulmonary cavitation with air-fluid level, accompanied by right-sided chest pain several weeks after first onset of symptoms. Considering a possible bact... |
32,778,857 | Quintessence Int | Delivering dental care as we emerge from the initial phase of the COVID-19 pandemic: teledentistry and face-to-face consultations in a new clinical world. | At a time when access to health care and services for the global population is a concern due to the COVID-19 pandemic, health professionals and their teams are struggling to find a way to adapt their practices. Dental professional organizations and decision-makers are required to provide guidance in a rapidly evolving ... | crisis management;dental trauma;emergency;evidence-based practice;telehealth | Journal Article | Talla, Pascaline Kengne;Levin, Liran;Glogauer, Michael;Cable, Cheryl;Allison, Paul J | 10.3290/j.qi.a44920 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Delivering dental care as we emerge from the initial phase of the COVID-19 pandemic: teledentistry and face-to-face consultations in a new clinical world. [Abstract]: At a time when access to health care and services for the global population is a concern due to the COVID-19 pandemic, health professionals and ... |
32,349,045 | Crit Pathw Cardiol | Coronovirus Disease-2019 (COVID-19) Pandemic and Cardiac Electrophysiology: Guidance Protocol From a UK Tertiary Cardiac Center. | Since December 2019, the coronovirus disease-2019 (COVID-19) pandemic has resulted in more than 2,160,000 positive cases and more than 145,000 deaths until April 18, 2020. The pressure to the health services worldwide has been unprecedented. The redeployment of staff and resources to treat more efficiently COVID-19 cas... | Journal Article | Katsaras, Dimitrios;Chalil, Shajil;Abozguia, Khalid | 10.1097/HPC.0000000000000226 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Coronovirus Disease-2019 (COVID-19) Pandemic and Cardiac Electrophysiology: Guidance Protocol From a UK Tertiary Cardiac Center. [Abstract]: Since December 2019, the coronovirus disease-2019 (COVID-19) pandemic has resulted in more than 2,160,000 positive cases and more than 145,000 deaths until April 18, 2020... | |
32,507,692 | Dig Liver Dis | Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases. | Objective: To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms. Methods: The clinical data of 164 COVID-19 patients with gastrointestinal symptoms were extracted and analysed retrospectively. Results: In total, 505 COVID-19 patients were divided into two gro... | covid-19;gastrointestinal symptoms;novel coronavirus;novel coronavirus pneumonia;sars-cov-2 | Journal Article;Research Support, Non-U.S. Gov't | Zhang, Hu;Liao, Yu-Sheng;Gong, Jing;Liu, Jing;Xia, Xi;Zhang, Heng | 10.1016/j.dld.2020.04.034 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases. [Abstract]: Objective: To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms. Methods: The clinical data of 164 COVID-19 patient... |
32,456,404 | Panminerva Med | The vaccine journey for COVID-19: a comprehensive systematic review of current clinical trials in humans. | INTRODUCTION: Since December 2019, there has been an outbreak of a novel beta-coronavirus (SARS-CoV-2) in Wuhan, China. On March the 11th the World Health Organization (WHO) declared COVID-19 as a pandemic, with over 118,000 cases in more than 110 countries around the world. In response to the global coronavirus diseas... | Journal Article | Checcucci, Enrico;Piramide, Federico;Pecoraro, Angela;Amparore, Daniele;Campi, Riccardo;Fiori, Cristian;Elhage, Oussama;Kotecha, Pinky;Vyakarnam, Annapurna;Serni, Sergio;Dasgupta, Prokar;Porpiglia, Francesco | 10.23736/S0031-0808.20.03958-0 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: The vaccine journey for COVID-19: a comprehensive systematic review of current clinical trials in humans. [Abstract]: INTRODUCTION: Since December 2019, there has been an outbreak of a novel beta-coronavirus (SARS-CoV-2) in Wuhan, China. On March the 11th the World Health Organization (WHO) declared COVID-19 a... | |
32,522,407 | Encephale | [How do children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) experience lockdown during the COVID-19 outbreak?] | OBJECTIVES: During the COVID-19 pandemic, the French government has decided a general lockdown. This unprecedented situation has raised concerns about children's and adolescent's mental health. Children and adolescents diagnosed with attention deficit hyperactivity disorder (ADHD) may find this context of restrained ac... | adhd;bien-etre;children;confinement;enfants;famille;family;lockdown;school;tdah;well-being;ecole | Journal Article | Bobo, E;Lin, L;Acquaviva, E;Caci, H;Franc, N;Gamon, L;Picot, M-C;Pupier, F;Speranza, M;Falissard, B;Purper-Ouakil, D | 10.1016/j.encep.2020.05.011 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [How do children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) experience lockdown during the COVID-19 outbreak?] [Abstract]: OBJECTIVES: During the COVID-19 pandemic, the French government has decided a general lockdown. This unprecedented situation has raised concerns about children's ... |
32,836,818 | Nonlinear Dyn | COVID-19: data-driven dynamics, statistical and distributed delay models, and observations. | COVID-19 was declared as a pandemic by the World Health Organization on March 11, 2020. Here, the dynamics of this epidemic is studied by using a generalized logistic function model and extended compartmental models with and without delays. For a chosen population, it is shown as to how forecasting may be done on the s... | delay integral equations;dynamics and control of epidemics;generalized logistic function;seiqr model;system identification | Journal Article | Liu, Xianbo;Zheng, Xie;Balachandran, Balakumar | 10.1007/s11071-020-05863-5 | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: COVID-19: data-driven dynamics, statistical and distributed delay models, and observations. [Abstract]: COVID-19 was declared as a pandemic by the World Health Organization on March 11, 2020. Here, the dynamics of this epidemic is studied by using a generalized logistic function model and extended compartmenta... |
32,528,774 | Cureus | Coronavirus Disease 2019 (COVID-19) in a Renal Transplant Patient. | Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality worldwide. Transplant patients are particularly at a higher risk of contracting COVID-19 because of their immunosuppressed state, and they have the propensity to develop opportunistic infections. The pre-immunosuppressed state, alon... | acute respiratory distress syndrome;coronavirus;covid-19;renal transplant | Case Reports | Chenna, Avantika;Konala, Venu Madhav;Gayam, Vijay;Naramala, Srikanth;Adapa, Sreedhar | 10.7759/cureus.8038 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Coronavirus Disease 2019 (COVID-19) in a Renal Transplant Patient. [Abstract]: Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality worldwide. Transplant patients are particularly at a higher risk of contracting COVID-19 because of their immunosuppressed state, and they have ... |
33,026,314 | Acta Med Port | [COVID-19 and Seasonal Flu During the Autumn-Winter of 2020/2021 and the Challenges Lying Ahead for Hospitals]. | The possibility of a second wave of the COVID-19 pandemic coexisting with a simultaneous epidemic of influenza and the co-circulation of other seasonal respiratory viruses sets the stage for a perfect storm. Preparing for the Autumn-Winter of 2020/2021 is complex, requiring centralized guidance but local and regional s... | covid-19;emergency service, hospital;influenza, human;seasons | Journal Article | Campos, Luis;Mansinho, Kamal;Telles de Freitas, Paulo;Ramos, Victor;Sakellarides, Constantino | 10.20344/amp.14818 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [COVID-19 and Seasonal Flu During the Autumn-Winter of 2020/2021 and the Challenges Lying Ahead for Hospitals]. [Abstract]: The possibility of a second wave of the COVID-19 pandemic coexisting with a simultaneous epidemic of influenza and the co-circulation of other seasonal respiratory viruses sets the stage ... |
32,748,336 | Am J Cardiovasc Drugs | Current Overview on Hypercoagulability in COVID-19. | The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboembolic complications,... | Journal Article;Review | Singhania, Namrata;Bansal, Saurabh;Nimmatoori, Divya P;Ejaz, Abutaleb A;McCullough, Peter A;Singhania, Girish | 10.1007/s40256-020-00431-z | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Current Overview on Hypercoagulability in COVID-19. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-asso... | |
32,924,827 | J Biomol Struct Dyn | Potential protease inhibitors and their combinations to block SARS-CoV-2. | COVID-19, which has emerged recently as a pandemic viral infection caused by SARS-coronavirus 2 has spread rapidly around the world, creating a public health emergency. The current situation demands an effective therapeutic strategy to control the disease using drugs that are approved, or by inventing new ones. The pre... | covid-19;tmprss2;main protease;molecular docking;spike protein | Journal Article | Abhinand, Chandran S;Nair, Achuthsankar S;Krishnamurthy, Anand;Oommen, Oommen V;Sudhakaran, Perumana R | 10.1080/07391102.2020.1819881 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Potential protease inhibitors and their combinations to block SARS-CoV-2. [Abstract]: COVID-19, which has emerged recently as a pandemic viral infection caused by SARS-coronavirus 2 has spread rapidly around the world, creating a public health emergency. The current situation demands an effective therapeutic s... |
32,909,541 | Clin Nephrol | An auspicious triumph of recovery from dialysis-requiring acute kidney injury in COVID-19 in a patient with chronic kidney disease, alpha-1 antitrypsin deficiency, and liver transplant: A case report. | We report a unique case of an immunosuppressed 67-year-old female with homozygous Z-allele mutation A1AT deficiency and liver transplant with baseline chronic kidney disease (CKD) stage IIIa with creatinine of 1 mg/dL and glomerular filtration rate (GFR) of 49 mL/min/1.73m(2) ~ 6 months before the presentation. She pre... | Case Reports;Journal Article | De Souza, Luisa;Nwanji, Valerie;Kaur, Gurwant | 10.5414/CN110294 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: An auspicious triumph of recovery from dialysis-requiring acute kidney injury in COVID-19 in a patient with chronic kidney disease, alpha-1 antitrypsin deficiency, and liver transplant: A case report. [Abstract]: We report a unique case of an immunosuppressed 67-year-old female with homozygous Z-allele mutatio... | |
32,186,277 | Euro Surveill | Rapidly increasing cumulative incidence of coronavirus disease (COVID-19) in the European Union/European Economic Area and the United Kingdom, 1 January to 15 March 2020. | The cumulative incidence of coronavirus disease (COVID-19) cases is showing similar trends in European Union/European Economic Area countries and the United Kingdom confirming that, while at a different stage depending on the country, the COVID-19 pandemic is progressing rapidly in all countries. Based on the experienc... | sars-cov-2, covid-19, coronavirus disease;coronavirus, eu/eea, united kingdom, europe | Journal Article | Kinross, Pete;Suetens, Carl;Gomes Dias, Joana;Alexakis, Leonidas;Wijermans, Ariana;Colzani, Edoardo;Monnet, Dominique L | 10.2807/1560-7917.ES.2020.25.11.2000285 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Rapidly increasing cumulative incidence of coronavirus disease (COVID-19) in the European Union/European Economic Area and the United Kingdom, 1 January to 15 March 2020. [Abstract]: The cumulative incidence of coronavirus disease (COVID-19) cases is showing similar trends in European Union/European Economic A... |
32,838,241 | EClinicalMedicine | Prevalence and prognostic value of Delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study. | Background: Delirium may be one of the presenting symptoms of COVID-19, complicating diagnosis and care of elderly patients with dementia. We aim to identify the prevalence and prognostic significance of delirium as the sole onset manifestation of COVID-19. Methods: This is a retrospective single-centre study based on ... | Journal Article | Poloni, Tino Emanuele;Carlos, Arenn Faye;Cairati, Marco;Cutaia, Chiara;Medici, Valentina;Marelli, Eleonora;Ferrari, Danila;Galli, Alberto;Bognetti, Paola;Davin, Annalisa;Cirrincione, Alice;Ceretti, Arcangelo;Cereda, Cristina;Ceroni, Mauro;Tronconi, Livio;Vitali, Silvia;Guaita, Antonio | 10.1016/j.eclinm.2020.100490 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Prevalence and prognostic value of Delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study. [Abstract]: Background: Delirium may be one of the presenting symptoms of COVID-19, complicating diagnosis and care of elderly patients with dementia. We aim to iden... | |
33,042,545 | Clin Case Rep | Spontaneous pneumothorax as a complication in COVID-19 male patient: A case report. | Coronavirus disease 2019 infection may be later complicated with pneumothorax after primarily symptoms. We must be aware about pneumothorax, which may be increased in cases of COVID-19. | cardiothoracic surgery;critical care medicine;infectious diseases;respiratory medicine;vascular surgery | Case Reports | Fahad, Ahmed Muhi;Mohammad, Ayam Ali;Al-Khalidi, Hasanain A;Alshewered, Ahmed Salih | 10.1002/ccr3.3378 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Spontaneous pneumothorax as a complication in COVID-19 male patient: A case report. [Abstract]: Coronavirus disease 2019 infection may be later complicated with pneumothorax after primarily symptoms. We must be aware about pneumothorax, which may be increased in cases of COVID-19. [Keywords]: cardiothoracic su... |
32,507,697 | J Surg Educ | How Has COVID-19 Affected the Costs of the Surgical Fellowship Interview Process? | OBJECTIVE: To evaluate the effect of COVID-19 on the costs of the surgical fellowship interview process. DESIGN: A literature review of the historical costs of surgical fellowship interviews and a summary of how the shift to virtual interviews has unintended positive and negative effects on costs for applicants and tra... | cost;fellowship;interview;match;recruitment;residency | Journal Article;Review | Tseng, Jennifer | 10.1016/j.jsurg.2020.05.018 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: How Has COVID-19 Affected the Costs of the Surgical Fellowship Interview Process? [Abstract]: OBJECTIVE: To evaluate the effect of COVID-19 on the costs of the surgical fellowship interview process. DESIGN: A literature review of the historical costs of surgical fellowship interviews and a summary of how the s... |
32,343,244 | Int Perspect Sex Reprod Health | Estimates of the Potential Impact of the COVID-19 Pandemic on Sexual and Reproductive Health In Low- and Middle-Income Countries. | The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the disease a global pandemic on March 11, 2020. Governments around the world have had to quickly adapt and respond to curb transmission of the virus and to prov... | Journal Article;Research Support, Non-U.S. Gov't | Riley, Taylor;Sully, Elizabeth;Ahmed, Zara;Biddlecom, Ann | 10.1363/46e9020 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Estimates of the Potential Impact of the COVID-19 Pandemic on Sexual and Reproductive Health In Low- and Middle-Income Countries. [Abstract]: The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the diseas... | |
32,665,942 | Eur J Case Rep Intern Med | Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia. | Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient with rapid worsening of COVID-19 pneumonia and its dramatic improv... | covid-19;computed tomography;coronavirus;corticosteroids;cytokine storm syndrome | Journal Article | Ruch, Yvon;Kaeuffer, Charlotte;Guffroy, Aurelien;Lefebvre, Nicolas;Hansmann, Yves;Danion, Francois | 10.12890/2020_001822 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia. [Abstract]: Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case ... |
32,023,681 | Zhonghua Nei Ke Za Zhi | [Diagnosis and clinical management of 2019 novel coronavirus infection: an operational recommendation of Peking Union Medical College Hospital (V2.0)]. | Since December 2019, China has been experiencing an outbreak of new infectious disease caused by 2019 novel coronavirus (2019-nCoV). The clinical features include fever, coughing, shortness of breath, and inflammatory pulmonary infiltration revealed by X ray. China rapidly identified 2019-nCoV-related pneumonia a statu... | diagnosis;management;novel coronavirus;pneumonia | English Abstract;Journal Article | 10.3760/cma.j.issn.0578-1426.2020.03.003 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: [Diagnosis and clinical management of 2019 novel coronavirus infection: an operational recommendation of Peking Union Medical College Hospital (V2.0)]. [Abstract]: Since December 2019, China has been experiencing an outbreak of new infectious disease caused by 2019 novel coronavirus (2019-nCoV). The clinical f... | |
32,947,271 | Physiol Meas | Remote health diagnosis and monitoring in the time of COVID-19. | Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. The clinical spectrum of SARS-CoV-2 pneumonia requires early detection and monitoring, within a clinical environment for critical cases and remotely for mild cases, with a l... | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Behar, Joachim A;Liu, Chengyu;Kotzen, Kevin;Tsutsui, Kenta;Corino, Valentina D A;Singh, Janmajay;Pimentel, Marco A F;Warrick, Philip;Zaunseder, Sebastian;Andreotti, Fernando;Sebag, David;Kopanitsa, Georgy;McSharry, Patrick E;Karlen, Walter;Karmakar, Chandan;Clifford, Gari D | 10.1088/1361-6579/abba0a | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Remote health diagnosis and monitoring in the time of COVID-19. [Abstract]: Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. The clinical spectrum of SARS-CoV-2 pneumonia requires early detection and monitoring, w... | |
32,767,652 | Catheter Cardiovasc Interv | Impact of COVID-19 pandemic on STEMI care: An expanded analysis from the United States. | OBJECTIVE: To evaluate the impact of COVID-19 pandemic migitation measures on of ST-elevation myocardial infarction (STEMI) care. BACKGROUND: We previously reported a 38% decline in cardiac catheterization activations during the early phase of the COVID-19 pandemic mitigation measures. This study extends our early obse... | covid-19;st-elevation myocardial infarction;stemi | Journal Article | Garcia, Santiago;Stanberry, Larissa;Schmidt, Christian;Sharkey, Scott;Megaly, Michael;Albaghdadi, Mazen S;Meraj, Perwaiz M;Garberich, Ross;Jaffer, Farouc A;Stefanescu Schmidt, Ada C;Dixon, Simon R;Rade, Jeffrey J;Smith, Timothy;Tannenbaum, Mark;Chambers, Jenny;Aguirre, Frank;Huang, Paul P;Kumbhani, Dharam J;Koshy, Thom... | 10.1002/ccd.29154 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Impact of COVID-19 pandemic on STEMI care: An expanded analysis from the United States. [Abstract]: OBJECTIVE: To evaluate the impact of COVID-19 pandemic migitation measures on of ST-elevation myocardial infarction (STEMI) care. BACKGROUND: We previously reported a 38% decline in cardiac catheterization activ... |
32,271,461 | Eur Rev Med Pharmacol Sci | COVID-19: emerging protective measures. | The COVID-19 (Coronavirus disease 2019) spreads primarily through droplets of saliva or discharge from the nose. COVID-19 is predominantly considered as an unavoidable pandemic, and scientists are very curious about how to provide the best protection to the public before a vaccine can be made available. There is an urg... | Journal Article | Balachandar, V;Mahalaxmi, I;Kaavya, J;Vivekanandhan, G;Ajithkumar, S;Arul, N;Singaravelu, G;Senthil Kumar, N;Mohana Dev, S | 10.26355/eurrev_202003_20713 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19: emerging protective measures. [Abstract]: The COVID-19 (Coronavirus disease 2019) spreads primarily through droplets of saliva or discharge from the nose. COVID-19 is predominantly considered as an unavoidable pandemic, and scientists are very curious about how to provide the best protection to the p... | |
32,571,647 | J Infect Chemother | A case report of SARS-CoV-2 confirmed in saliva specimens up to 37 days after onset: Proposal of saliva specimens for COVID-19 diagnosis and virus monitoring. | We present the case of a 71-year-old man who, despite becoming asymptomatic after having some mild symptoms of COVID-19, had SARS-CoV-2 RNA detected for 37 days after onset, from his concentrated and purified saliva specimens using sugar chain-immobilized gold nanoparticles. It was suggested that the early morning sali... | covid-19;rt-pcr;sars-cov-2;saliva;sugar chain-immobilized magnetic gold nanoparticle;virus shedding | Case Reports | Tajima, Yasuhisa;Suda, Yasuo;Yano, Kunio | 10.1016/j.jiac.2020.06.011 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: A case report of SARS-CoV-2 confirmed in saliva specimens up to 37 days after onset: Proposal of saliva specimens for COVID-19 diagnosis and virus monitoring. [Abstract]: We present the case of a 71-year-old man who, despite becoming asymptomatic after having some mild symptoms of COVID-19, had SARS-CoV-2 RNA ... |
32,878,518 | J Asthma | Risk factors of non-adherence to guidelines for the prevention of COVID-19 among young adults with asthma in a region with a high risk of a COVID-19 outbreak. | OBJECTIVE: SARS-CoV-2 disease 2019 (COVID-19) is highly contagious and spreads rapidly. The application of preventive measures has proven to be the best strategy to minimize the number of patients and the dissemination of and deaths from COVID-19. The objective of this study was to determine the risk factors that limit... | covid-19 outbreak;adherence;asthma;education;to prevent | Journal Article | Vazquez-Nava, Francisco;Vazquez-Rodriguez, Eliza M;Vazquez-Rodriguez, Carlos F;Betancourt, Nancy V Ortega;Ruiz, Octelina Castillo;Rodriguez-Castillejos, Guadalupe C | 10.1080/02770903.2020.1818774 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Risk factors of non-adherence to guidelines for the prevention of COVID-19 among young adults with asthma in a region with a high risk of a COVID-19 outbreak. [Abstract]: OBJECTIVE: SARS-CoV-2 disease 2019 (COVID-19) is highly contagious and spreads rapidly. The application of preventive measures has proven to... |
32,543,892 | SAR QSAR Environ Res | Development of a simple, interpretable and easily transferable QSAR model for quick screening antiviral databases in search of novel 3C-like protease (3CLpro) enzyme inhibitors against SARS-CoV diseases. | In the context of recently emerged pandemic of COVID-19, we have performed two-dimensional quantitative structure-activity relationship (2D-QSAR) modelling using SARS-CoV-3CLpro enzyme inhibitors for the development of a multiple linear regression (MLR) based model. We have used 2D descriptors with an aim to develop an... | 2d-qsar;3clpro enzyme;covid-19;mlr;sars-cov-2;docking and virtual screening | Journal Article | Kumar, V;Roy, K | 10.1080/1062936X.2020.1776388 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Development of a simple, interpretable and easily transferable QSAR model for quick screening antiviral databases in search of novel 3C-like protease (3CLpro) enzyme inhibitors against SARS-CoV diseases. [Abstract]: In the context of recently emerged pandemic of COVID-19, we have performed two-dimensional quan... |
32,836,476 | Soc Sci Q | Analysis of Youths' Perspective in India On and During the Pandemic of COVID-19. | Objective: In this COVID-19 pandemic, there are not many sound studies focusing on the extensive socioeconomic impact ushered in with this disaster. This work aims to understand the thought of the youth, their opinions and understanding of various aspects of the COVID-19 pandemic. Methodology: Using a combined qualitat... | Journal Article | Basu, Aman;Roy, Ajishnu;Hazra, Amit Kumar;Pramanick, Kousik | 10.1111/ssqu.12839 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Analysis of Youths' Perspective in India On and During the Pandemic of COVID-19. [Abstract]: Objective: In this COVID-19 pandemic, there are not many sound studies focusing on the extensive socioeconomic impact ushered in with this disaster. This work aims to understand the thought of the youth, their opinions... | |
32,589,264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | BACKGROUND: Initial evidence from China suggests that most vulnerable subjects to COVID-19 infection suffer from pre-existing illness, including metabolic abnormalities. The pandemic characteristics and high-lethality rate of COVID-19 infection have raised concerns about interactions between virus pathobiology and comp... | sars-cov-2;fatty liver;mitochondria;nitrosative stress;oxidative stress | Journal Article;Review | Portincasa, Piero;Krawczyk, Marcin;Smyk, Wiktor;Lammert, Frank;Di Ciaula, Agostino | 10.1111/eci.13338 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. [Abstract]: BACKGROUND: Initial evidence from China suggests that most vulnerable subjects to COVID-19 infection suffer from pre-existing illness, including metabolic abnormalities. The pandemic characteristics and high-lethality rate ... |
32,671,537 | Matern Child Health J | Using Prenatal Blood Samples to Evaluate COVID-19 Rapid Serologic Tests Specificity. | INTRODUCTION: Background cross-reactivity with other coronaviruses may reduce the specificity of COVID-19 rapid serologic tests. The vast majority of women attend prenatal care, which is a unique source of population-based blood samples appropriate for validation studies. We used stored 2018 serum samples from an exist... | covid-19 diagnostic testing;pregnancy;prenatal care;serologic tests | Journal Article | Alger, Jackeline;Cafferata, Maria Luisa;Alvarado, Tito;Ciganda, Alvaro;Corrales, Arturo;Desale, Hans;Drouin, Arnaud;Fusco, Dahlene;Garcia, Jorge;Gibbons, Luz;Harville, Emily;Lopez, Wendy;Lorenzana, Ivette;Munoz-Lara, Fausto;Palou, Elsa;Retes, Eduardo;Sierra, Manuel;Stella, Candela;Xiong, Xu;Zambrano, Lysien I;Buekens, ... | 10.1007/s10995-020-02981-9 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Using Prenatal Blood Samples to Evaluate COVID-19 Rapid Serologic Tests Specificity. [Abstract]: INTRODUCTION: Background cross-reactivity with other coronaviruses may reduce the specificity of COVID-19 rapid serologic tests. The vast majority of women attend prenatal care, which is a unique source of populati... |
32,882,627 | Epilepsy Behav | An accelerated shift in the use of remote systems in epilepsy due to the COVID-19 pandemic. | PURPOSE: The purpose of the study was to describe epileptologists' opinion on the increased use of remote systems implemented during the COVID-19 pandemic across clinics, education, and scientific meetings activities. METHODS: Between April and May 2020, we conducted a cross-sectional, electronic survey on remote syste... | e-health;e-learning;remote work system;teleconsultations;telemedicine;virtual meeting | Journal Article | Kuchenbuch, Mathieu;D'Onofrio, Gianluca;Wirrell, Elaine;Jiang, Yuwu;Dupont, Sophie;Grinspan, Zachary M;Auvin, Stephane;Wilmshurst, Jo M;Arzimanoglou, Alexis;Cross, J Helen;Specchio, Nicola;Nabbout, Rima | 10.1016/j.yebeh.2020.107376 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: An accelerated shift in the use of remote systems in epilepsy due to the COVID-19 pandemic. [Abstract]: PURPOSE: The purpose of the study was to describe epileptologists' opinion on the increased use of remote systems implemented during the COVID-19 pandemic across clinics, education, and scientific meetings a... |
32,451,533 | Am J Clin Pathol | Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases. | OBJECTIVES: To report methods and findings of 2 autopsies with molecular evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals. METHODS: Postmortem examination was completed following Centers for Disease Control and Prevention public guidelines. Numerous formalin-fixed paraffin... | autopsy;covid-19;ffpe;molecular testing;sars-cov-2; coronavirus;viral sequencing;ncov-19 | Case Reports;Journal Article | Sekulic, Miroslav;Harper, Holly;Nezami, Behtash G;Shen, Daniel L;Sekulic, Simona Pichler;Koeth, Aaron T;Harding, Clifford V;Gilmore, Hannah;Sadri, Navid | 10.1093/ajcp/aqaa091 | [
0,
1,
0,
1,
0,
0,
0
] | [Title]: Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases. [Abstract]: OBJECTIVES: To report methods and findings of 2 autopsies with molecular evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals. METHODS: Post... |
32,786,258 | ACS Chem Biol | Chemical Probes for Blocking of Influenza A M2 Wild-type and S31N Channels. | We report on using the synthetic aminoadamantane-CH2-aryl derivatives 1-6 as sensitive probes for blocking M2 S31N and influenza A virus (IAV) M2 wild-type (WT) channels as well as virus replication in cell culture. The binding kinetics measured using electrophysiology (EP) for M2 S31N channel are very dependent on the... | Journal Article;Research Support, Non-U.S. Gov't | Tzitzoglaki, Christina;McGuire, Kelly;Lagarias, Panagiotis;Konstantinidi, Athina;Hoffmann, Anja;Fokina, Natalie A;Ma, Chulong;Papanastasiou, Ioannis P;Schreiner, Peter R;Vazquez, Santiago;Schmidtke, Michaela;Wang, Jun;Busath, David D;Kolocouris, Antonios | 10.1021/acschembio.0c00553 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Chemical Probes for Blocking of Influenza A M2 Wild-type and S31N Channels. [Abstract]: We report on using the synthetic aminoadamantane-CH2-aryl derivatives 1-6 as sensitive probes for blocking M2 S31N and influenza A virus (IAV) M2 wild-type (WT) channels as well as virus replication in cell culture. The bin... | |
32,869,005 | Heliyon | A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2. | The -1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces the survival of the virus. This study aimed to successfully develop a toolkit for screening antiviral ... | -1 ribosomal frameshifting;biomedical engineering;drug screen;microbial biotechnology;molecular biology;peptides;protein engineering;sars-cov-2;virology | Journal Article | Chen, Yanqiong;Tao, Huan;Shen, Silan;Miao, Zhiyong;Li, Lili;Jia, Yongqian;Zhang, Hu;Bai, Xiufeng;Fu, Xinyuan | 10.1016/j.heliyon.2020.e04793 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2. [Abstract]: The -1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces t... |
33,074,904 | Ann Surg | Stereotactic Body Radiotherapy Versus Delayed Surgery for Early-stage Non-small-cell Lung Cancer. | OBJECTIVE: To evaluate the overall survival of patients with operable stage IA non-small-cell lung cancer (NSCLC) who undergo "early" SBRT (within 0-30 days after diagnosis) versus "delayed" surgery (90-120 days after diagnosis). SUMMARY OF BACKGROUND DATA: During the COVID-19 pandemic, national guidelines have recomme... | Comparative Study;Journal Article | Mayne, Nicholas R;Lin, Belle K;Darling, Alice J;Raman, Vignesh;Patel, Deven C;Liou, Douglas Z;D'Amico, Thomas A;Yang, Chi-Fu Jeffrey | 10.1097/SLA.0000000000004363 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Stereotactic Body Radiotherapy Versus Delayed Surgery for Early-stage Non-small-cell Lung Cancer. [Abstract]: OBJECTIVE: To evaluate the overall survival of patients with operable stage IA non-small-cell lung cancer (NSCLC) who undergo "early" SBRT (within 0-30 days after diagnosis) versus "delayed" surgery (9... | |
32,409,443 | Cleve Clin J Med | Respiratory failure in patients infected with SARS-CoV-2. | The management of patients with COVID-19-induced acute respiratory distress syndrome focuses on identifying the causes for respiratory failure and on following best practices for supportive care with oxygen supplementation and mechanical ventilation. In this patient population, appropriate measures need to be taken to ... | Journal Article | Vashisht, Rishik;Duggal, Abhijit | 10.3949/ccjm.87a.ccc025 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Respiratory failure in patients infected with SARS-CoV-2. [Abstract]: The management of patients with COVID-19-induced acute respiratory distress syndrome focuses on identifying the causes for respiratory failure and on following best practices for supportive care with oxygen supplementation and mechanical ven... | |
33,048,119 | Jpn J Clin Oncol | Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan. | BACKGROUND: The purpose of this study was to determine whether a uniform infection screening protocol could be used to safely perform head and neck cancer surgery during the coronavirus disease 2019 pandemic and clarify how surgical treatment changed compared with the pre-pandemic period. MATERIALS AND METHODS: During ... | covid-19;sars-cov-2;head and neck surgery;infection screening;pandemic | Journal Article | Ito, Akiko;Kobayashi, Kenya;Shiotsuka, Mika;Sato, Tetsufumi;Omura, Go;Matsumoto, Yoshifumi;Ikeda, Atsuo;Sakai, Azusa;Eguchi, Kohtaro;Takano, Tomonari;Matsumoto, Fumihiko;Kobayashi, Osamu;Iwata, Satoshi;Yoshimoto, Seiichi | 10.1093/jjco/hyaa195 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan. [Abstract]: BACKGROUND: The purpose of this study was to determine whether a uniform infection screening protocol could be used to safely perform head and neck cancer surgery during the coronav... |
33,017,826 | Blood Purif | Peritoneal Dialysis Is an Option for Acute Kidney Injury Management in Patients with COVID-19. | In December 2019, cases of acute respiratory illness of unknown origin were reported in Wuhan, China. The disease is caused by "severe acute respiratory syndrome coronavirus 2". After identifying severe lung damage, injury to other organs, such as the kidney, has been identified. Peritoneal dialysis is a renal replacem... | acute kidney injury;covid-19 disease;peritoneal dialysis | Journal Article;Review | Rodriguez-Chagolla, Jose M;Vasquez Jimenez, Enzo;Herrera Arellano, Leticia;Villa Torres, Alberto;Acosta Garcia, Nayeli;Aleman Quimbiulco, Dolores;Armeaga Aguilar, Sergio;Madero, Magdalena | 10.1159/000511390 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Peritoneal Dialysis Is an Option for Acute Kidney Injury Management in Patients with COVID-19. [Abstract]: In December 2019, cases of acute respiratory illness of unknown origin were reported in Wuhan, China. The disease is caused by "severe acute respiratory syndrome coronavirus 2". After identifying severe l... |
32,883,670 | AJNR Am J Neuroradiol | MRI Brain Findings in 126 Patients with COVID-19: Initial Observations from a Descriptive Literature Review. | BACKGROUND AND PURPOSE: Recently, numerous investigational studies, case series, and case reports have been published describing various MR imaging brain findings in patients with COVID-19. The purpose of this literature review was to compile and analyze brain MR imaging findings in patients with COVID-19-related illne... | Journal Article;Review | Gulko, E;Oleksk, M L;Gomes, W;Ali, S;Mehta, H;Overby, P;Al-Mufti, F;Rozenshtein, A | 10.3174/ajnr.A6805 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: MRI Brain Findings in 126 Patients with COVID-19: Initial Observations from a Descriptive Literature Review. [Abstract]: BACKGROUND AND PURPOSE: Recently, numerous investigational studies, case series, and case reports have been published describing various MR imaging brain findings in patients with COVID-19. ... | |
32,741,731 | J Infect Public Health | Coronaviruses disease 2019 (COVID-19): Causative agent, mental health concerns, and potential management options. | Coronavirus disease-2019 (COVID-19) pandemic started from Wuhan, China has infected more than 6.7 million individuals and killed more than 390,000 individuals globally. Due to the higher transmissibility and infectiousness, asymptomatic infection, and lack of effective treatment options and vaccine, fatalities and morb... | covid-19;coronaviruses;infectiousness;transmission | Journal Article;Review | Khan, Suliman;Siddique, Rabeea;Bai, Qian;Shabana;Liu, Yang;Xue, Mengzhou;Nabi, Ghulam;Liu, Jianbo | 10.1016/j.jiph.2020.07.010 | [
1,
0,
1,
0,
1,
0,
0
] | [Title]: Coronaviruses disease 2019 (COVID-19): Causative agent, mental health concerns, and potential management options. [Abstract]: Coronavirus disease-2019 (COVID-19) pandemic started from Wuhan, China has infected more than 6.7 million individuals and killed more than 390,000 individuals globally. Due to the highe... |
32,638,632 | Am J Hosp Palliat Care | Palliative Care Team Involvement in Patients With COVID-19 in New York City. | BACKGROUND: With the highest number of cases in the world as of April 13, 2020, New York City (NYC) became the epicenter of the global coronavirus disease 2019 (COVID-19) pandemic. The data regarding palliative team involvement in patients with COVID-19, however, remains scarce. We aimed to investigate outcomes of pall... | covid-19;new york;cardiopulmonary resuscitation;palliative care | Journal Article | Obata, Reiichiro;Maeda, Tetsuro;Rizk, Dahlia;Kuno, Toshiki | 10.1177/1049909120940986 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Palliative Care Team Involvement in Patients With COVID-19 in New York City. [Abstract]: BACKGROUND: With the highest number of cases in the world as of April 13, 2020, New York City (NYC) became the epicenter of the global coronavirus disease 2019 (COVID-19) pandemic. The data regarding palliative team involv... |
32,493,734 | Cleve Clin J Med | New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response. | In April 2020, data began emerging on Kawasaki-like syndrome and hyperinflammatory response in children with COVID-19. Since then, much has been published on the presentation of COVID-19 in pediatric patients, including its association with Kawasaki disease and the multisystem inflammatory syndrome in children (MIS-C).... | Journal Article | Panupattanapong, Sirada;Brooks, Elizabeth B | 10.3949/ccjm.87a.ccc039 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response. [Abstract]: In April 2020, data began emerging on Kawasaki-like syndrome and hyperinflammatory response in children with COVID-19. Since then, much has been published on the presentation of COVID-19 in p... | |
32,730,211 | IEEE Trans Med Imaging | Accurate Screening of COVID-19 Using Attention-Based Deep 3D Multiple Instance Learning. | Automated Screening of COVID-19 from chest CT is of emergency and importance during the outbreak of SARS-CoV-2 worldwide in 2020. However, accurate screening of COVID-19 is still a massive challenge due to the spatial complexity of 3D volumes, the labeling difficulty of infection areas, and the slight discrepancy betwe... | Journal Article | Han, Zhongyi;Wei, Benzheng;Hong, Yanfei;Li, Tianyang;Cong, Jinyu;Zhu, Xue;Wei, Haifeng;Zhang, Wei | 10.1109/TMI.2020.2996256 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Accurate Screening of COVID-19 Using Attention-Based Deep 3D Multiple Instance Learning. [Abstract]: Automated Screening of COVID-19 from chest CT is of emergency and importance during the outbreak of SARS-CoV-2 worldwide in 2020. However, accurate screening of COVID-19 is still a massive challenge due to the ... | |
32,665,963 | Mol Ther Methods Clin Dev | Characteristics of the Coronavirus Disease 2019 and related Therapeutic Options. | The coronavirus disease 2019 (COVID-19) is a new type of pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. COVID-19 is affecting millions of patients, and the infected number keeps increasing. SARS-CoV-2 is highly infectious, has a long incubation period, and causes a relativel... | Journal Article;Review | Huang, Boxuan;Ling, Rongsong;Cheng, Yifan;Wen, Jieqi;Dai, Yarong;Huang, Wenjie;Zhang, Siyan;Lu, Xifeng;Luo, Yifeng;Jiang, Yi-Zhou | 10.1016/j.omtm.2020.06.013 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Characteristics of the Coronavirus Disease 2019 and related Therapeutic Options. [Abstract]: The coronavirus disease 2019 (COVID-19) is a new type of pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. COVID-19 is affecting millions of patients, and the infected number k... | |
32,893,293 | Rheumatology (Oxford) | Telemedicine in rheumatology: a reliable approach beyond the pandemic. | OBJECTIVES: The SARS-CoV-2 outbreak has imposed considerable restrictions on people's mobility, which affects the referral of chronically ill patients to health care structures. The emerging need for alternative ways to follow these patients up is leading to a wide adoption of telemedicine. We aimed to evaluate the fea... | covid-19;sars-cov-2;connective tissue diseases;idiopathic inflammatory myopathies;systemic lupus erythematosus;systemic sclerosis;tele-rheumatology;telemedicine | Journal Article | Cavagna, Lorenzo;Zanframundo, Giovanni;Codullo, Veronica;Pisu, Maria Grazia;Caporali, Roberto;Montecucco, Carlomaurizio | 10.1093/rheumatology/keaa554 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Telemedicine in rheumatology: a reliable approach beyond the pandemic. [Abstract]: OBJECTIVES: The SARS-CoV-2 outbreak has imposed considerable restrictions on people's mobility, which affects the referral of chronically ill patients to health care structures. The emerging need for alternative ways to follow t... |
32,445,083 | Target Oncol | Impact of the COVID-19 Outbreak on the Management of Patients with Cancer. | The coronavirus SARS-CoV-2 (COVID-19) outbreak is having a profound impact on the management of patients with cancer. In this review, we comprehensively investigate the various aspects of cancer care during the pandemic, taking advantage of data generated in Asia and Europe at the frontline of the COVID-19 pandemic spr... | Journal Article;Review | Raymond, Eric;Thieblemont, Catherine;Alran, Severine;Faivre, Sandrine | 10.1007/s11523-020-00721-1 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Impact of the COVID-19 Outbreak on the Management of Patients with Cancer. [Abstract]: The coronavirus SARS-CoV-2 (COVID-19) outbreak is having a profound impact on the management of patients with cancer. In this review, we comprehensively investigate the various aspects of cancer care during the pandemic, tak... | |
32,376,589 | Nan Fang Yi Ke Da Xue Xue Bao | [Chest CT findings and their dynamic changes in patients with COVID-19]. | ObjectiveTo define chest CT findings and their dynamic changes in patients with coronavirus disease 2019 (COVID-19) from disease onset to the cure.MethodWe analyzed the clinical and chest CT data of 6 patients with RT-PCR-confirmed COVID-19. According to the time from the disease onset to the cure or from the onset to ... | coronavirus disease 2019;dynamic change;tomography, x-ray computed | Journal Article | Xiang, Ying;Yang, Quanxin;Sun, Honghong;Qin, Xingru;Li, Xiaohui;Zhang, Qiujuan | 10.12122/j.issn.1673-4254.2020.03.05 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: [Chest CT findings and their dynamic changes in patients with COVID-19]. [Abstract]: ObjectiveTo define chest CT findings and their dynamic changes in patients with coronavirus disease 2019 (COVID-19) from disease onset to the cure.MethodWe analyzed the clinical and chest CT data of 6 patients with RT-PCR-conf... |
32,553,061 | Euro Surveill | Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications. | We reviewed the diagnostic accuracy of SARS-CoV-2 serological tests. Random-effects models yielded a summary sensitivity of 82% for IgM, and 85% for IgG and total antibodies. For specificity, the pooled estimate were 98% for IgM and 99% for IgG and total antibodies. In populations with </= 5% of seroconverted individua... | sars-cov-2;meta-analysis;predictive values;sensitivity;serological tests;specificity;systematic review | Journal Article;Meta-Analysis | Caini, Saverio;Bellerba, Federica;Corso, Federica;Diaz-Basabe, Angelica;Natoli, Gioacchino;Paget, John;Facciotti, Federica;De Angelis, Simone Pietro;Raimondi, Sara;Palli, Domenico;Mazzarella, Luca;Pelicci, Pier Giuseppe;Vineis, Paolo;Gandini, Sara | 10.2807/1560-7917.ES.2020.25.23.2000980 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications. [Abstract]: We reviewed the diagnostic accuracy of SARS-CoV-2 serological tests. Random-effects models yielded a summary sensitivity of 82% for IgM, and 85% for IgG and tot... |
32,926,664 | Telemed J E Health | Rapid Increase in Telemental Health Within the Department of Veterans Affairs During the COVID-19 Pandemic. | Background: The use of telemental health via videoconferencing (TMH-V) became critical during the Coronavirus disease 2019 (COVID-19) pandemic due to restriction of non-urgent in-person appointments. The current brief report demonstrates the rapid growth in TMH-V appointments in the weeks following the pandemic declara... | behavioral health;psychiatry;psychology;telehealth;telemedicine;telepsychiatry | Journal Article | Connolly, Samantha L;Stolzmann, Kelly L;Heyworth, Leonie;Weaver, Kendra R;Bauer, Mark S;Miller, Christopher J | 10.1089/tmj.2020.0233 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Rapid Increase in Telemental Health Within the Department of Veterans Affairs During the COVID-19 Pandemic. [Abstract]: Background: The use of telemental health via videoconferencing (TMH-V) became critical during the Coronavirus disease 2019 (COVID-19) pandemic due to restriction of non-urgent in-person appoi... |
32,344,304 | Med Hypotheses | May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications? | COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females. Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly... | Journal Article | Adamowicz, Jan;Juszczak, Kajetan;Drewa, Tomasz | 10.1016/j.mehy.2020.109751 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications? [Abstract]: COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison ... | |
32,352,421 | Med Lav | Occupational Medicine in the time of COVID-19. | Editorial. | Journal Article | Mutti, Antonio | 10.23749/mdl.v111i2.9546 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Occupational Medicine in the time of COVID-19. [Abstract]: Editorial. [Keywords]: | |
32,687,406 | Am J Physiol Cell Physiol | Inhibiting fusion with cellular membrane system: therapeutic options to prevent severe acute respiratory syndrome coronavirus-2 infection. | Severe acute respiratory syndrome coronavirus (SARS-CoV), an enveloped virus with a positive-sense single-stranded RNA genome, facilitates the host cell entry through intricate interactions with proteins and lipids of the cell membrane. The detailed molecular mechanism involves binding to the host cell receptor and fus... | ace2;sars-cov-2;endocytosis;receptor binding motif;serine protease inhibitors | Journal Article;Research Support, Non-U.S. Gov't;Review | Mitra, Prasenjit | 10.1152/ajpcell.00260.2020 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Inhibiting fusion with cellular membrane system: therapeutic options to prevent severe acute respiratory syndrome coronavirus-2 infection. [Abstract]: Severe acute respiratory syndrome coronavirus (SARS-CoV), an enveloped virus with a positive-sense single-stranded RNA genome, facilitates the host cell entry t... |
32,464,670 | Laryngorhinootologie | [Implementation of an operational concept in an ENT clinic in the context of the SARS-CoV-2 pandemic]. | The SARS-CoV-2 pandemic poses major challenges for the entire medical care system. Especially in university institutions as maximum care providers, a higher exposure to potentially infectious patients or actual COVID-19 patients is to be expected. In a short period of time, an operational concept had to be developed re... | Journal Article | Weiss, Roxanne;Loth, Andreas;Guderian, Daniela;Diensthuber, Marc;Kempf, Volkhard;Hack, Daniel;Wicker, Sabine;Ciesek, Sandra;Graf, Jurgen;Stover, Timo;Leinung, Martin | 10.1055/a-1174-0234 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [Implementation of an operational concept in an ENT clinic in the context of the SARS-CoV-2 pandemic]. [Abstract]: The SARS-CoV-2 pandemic poses major challenges for the entire medical care system. Especially in university institutions as maximum care providers, a higher exposure to potentially infectious pati... | |
32,913,866 | World J Clin Cases | Spontaneous pneumomediastinum in an elderly COVID-19 patient: A case report. | BACKGROUND: Spontaneous pneumomediastinum (SPM) is more common in young adults, usually caused by external factors like trauma. It causes symptoms such as chest pain or dyspnea, but it is rare to see elderly patients who develop SPM. Here we report the case of an elderly patient diagnosed with coronavirus disease 2019 ... | aging;covid-19;case report;sars;spontaneous pneumomediastinum | Case Reports | Kong, Ning;Gao, Chen;Xu, Mao-Sheng;Xie, Yuan-Liang;Zhou, Chang-Yu | 10.12998/wjcc.v8.i16.3573 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Spontaneous pneumomediastinum in an elderly COVID-19 patient: A case report. [Abstract]: BACKGROUND: Spontaneous pneumomediastinum (SPM) is more common in young adults, usually caused by external factors like trauma. It causes symptoms such as chest pain or dyspnea, but it is rare to see elderly patients who d... |
32,629,804 | Viruses | Repurposing Therapeutics for Potential Treatment of SARS-CoV-2: A Review. | The need for proven disease-specific treatments for the novel pandemic coronavirus SARS-CoV-2 necessitates a worldwide search for therapeutic options. Since the SARS-CoV-2 virus shares extensive homology with SARS-CoV and MERS-CoV, effective therapies for SARS-CoV and MERS-CoV may also have therapeutic potential for th... | covid-19;sars-cov-2;coronavirus;repositioning;repurposing;therapeutics;treatment | Journal Article;Research Support, Non-U.S. Gov't;Review | Santos, Jennifer;Brierley, Stephanie;Gandhi, Mohit J;Cohen, Michael A;Moschella, Phillip C;Declan, Arwen B L | 10.3390/v12070705 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Repurposing Therapeutics for Potential Treatment of SARS-CoV-2: A Review. [Abstract]: The need for proven disease-specific treatments for the novel pandemic coronavirus SARS-CoV-2 necessitates a worldwide search for therapeutic options. Since the SARS-CoV-2 virus shares extensive homology with SARS-CoV and MER... |
33,045,553 | J Affect Disord | Recommendations for the care of patients with bipolar disorder during the COVID-19 pandemic. | In recent months, there has been a rapid spread of coronavirus disease (COVID-19), being now regarded as a global pandemic. In this context, the governments of different countries have established strict containment measures, and subsequent deconfinement measures, with consequential alterations in the rhythms and livin... | bipolar disorder;covid-19;recommendations for clinicians | Journal Article;Review | Hernandez-Gomez, Alba;Andrade-Gonzalez, Nelson;Lahera, Guillermo;Vieta, Eduard | 10.1016/j.jad.2020.09.105 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Recommendations for the care of patients with bipolar disorder during the COVID-19 pandemic. [Abstract]: In recent months, there has been a rapid spread of coronavirus disease (COVID-19), being now regarded as a global pandemic. In this context, the governments of different countries have established strict co... |
32,799,852 | BMC Cardiovasc Disord | Implications of AB0 blood group in hypertensive patients with covid-19. | BACKGROUND: Hypertension is the most frequent co-morbidity in patients with covid-19 infection, and we might speculate that a specific blood group could play a key role in the clinical outcome of hypertensive patients with covid-19. METHODS: In this prospective study, we compared 0 vs. non-0 blood group in hypertensive... | coagulopathy;covid-19;hypertension | Comparative Study;Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Sardu, Celestino;Marfella, Raffaele;Maggi, Paolo;Messina, Vincenzo;Cirillo, Paolo;Codella, Vinicio;Gambardella, Jessica;Sardu, Antonio;Gatta, Gianluca;Santulli, Gaetano;Paolisso, Giuseppe | 10.1186/s12872-020-01658-z | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Implications of AB0 blood group in hypertensive patients with covid-19. [Abstract]: BACKGROUND: Hypertension is the most frequent co-morbidity in patients with covid-19 infection, and we might speculate that a specific blood group could play a key role in the clinical outcome of hypertensive patients with covi... |
32,968,798 | Brief Bioinform | Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade. | The novel coronavirus or COVID-19 has first been found in Wuhan, China, and became pandemic. Angiotensin-converting enzyme 2 (ACE2) plays a key role in the host cells as a receptor of Spike-I Glycoprotein of COVID-19 which causes final infection. ACE2 is highly expressed in the bladder, ileum, kidney and liver, compari... | Journal Article;Research Support, Non-U.S. Gov't | Dey, Ashmita;Sen, Sagnik;Maulik, Ujjwal | 10.1093/bib/bbaa214 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Unveiling COVID-19-associated organ-specific cell types and cell-specific pathway cascade. [Abstract]: The novel coronavirus or COVID-19 has first been found in Wuhan, China, and became pandemic. Angiotensin-converting enzyme 2 (ACE2) plays a key role in the host cells as a receptor of Spike-I Glycoprotein of ... | |
32,747,596 | BMJ Case Rep | Use of awake proning to avoid invasive ventilation in a patient with severe COVID-19 pneumonitis. | A 60-year-old man with swab-positive COVID-19 and extensive ground-glass change seen on CT imaging was successfully managed on our COVID-19 high-dependency unit with only low-flow oxygen and strict awake proning instructions. He was successfully weaned off oxygen entirely without any requirement for non-invasive or inv... | adult intensive care;mechanical ventilation;respiratory medicine | Case Reports;Journal Article | Whittemore, Paul;Macfarlane, Laura;Herbert, Anna;Farrant, John | 10.1136/bcr-2020-236586 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Use of awake proning to avoid invasive ventilation in a patient with severe COVID-19 pneumonitis. [Abstract]: A 60-year-old man with swab-positive COVID-19 and extensive ground-glass change seen on CT imaging was successfully managed on our COVID-19 high-dependency unit with only low-flow oxygen and strict awa... |
32,734,810 | J Pharm Pract | Hydroxychloroquine Alternatives for Chronic Disease: Response to a Growing Shortage Amid the Global COVID-19 Pandemic. | With the emergence of a novel severe acute respiratory syndrome coronavirus, investigators worldwide are scrambling to identify appropriate treatment modalities, develop accurate testing, and produce a vaccine. To date, effective treatment remains elusive. Chloroquine phosphate and hydroxychloroquine sulfate (HCQ), wel... | coronavirus disease 2019;distributive justice;hydroxychloroquine;nonmaleficence | Journal Article | Husayn, Sameeha S;Brown, Jeremy D;Presley, Colby L;Boghean, Kelsey;Waller, Jacquelyn D | 10.1177/0897190020942658 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: Hydroxychloroquine Alternatives for Chronic Disease: Response to a Growing Shortage Amid the Global COVID-19 Pandemic. [Abstract]: With the emergence of a novel severe acute respiratory syndrome coronavirus, investigators worldwide are scrambling to identify appropriate treatment modalities, develop accurate t... |
32,556,054 | An Acad Bras Cienc | COVID-19: therapeutic approaches description and discussion. | COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to t... | Journal Article;Review | Trindade, Guilherme G;Caxito, Samyra M C;Xavier, Alessandra Rejane E O;Xavier, Mauro A S;BrandAo, Fabiana | 10.1590/0001-3765202020200466 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: COVID-19: therapeutic approaches description and discussion. [Abstract]: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since th... | |
32,633,410 | Eur Rev Med Pharmacol Sci | COVID-19 with bronchogram - a potential indication of prolonged treatment. | Novel coronavirus disease-19 (COVID-19) has widely spread all over the world and seriously threatened people's health. This disease is currently diagnosed by clinical features, chest computed tomography (CT) scan, and nucleic acid test of severe acute respiratory syndrome coronavirus (SARS-CoV-2). Recently, some studie... | Case Reports;Journal Article | Qian, W-J;Li, L;Sun, L-Y;Shi, H-R;Liu, H;Jing, X | 10.26355/eurrev_202006_21709 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: COVID-19 with bronchogram - a potential indication of prolonged treatment. [Abstract]: Novel coronavirus disease-19 (COVID-19) has widely spread all over the world and seriously threatened people's health. This disease is currently diagnosed by clinical features, chest computed tomography (CT) scan, and nuclei... | |
32,854,562 | J Orthod | The effective use of an e-dentistry service during the COVID-19 crisis. | In 2020, we experienced the largest disruption to normal life recorded in recent years with the COVID-19 global pandemic. Creative thinking was required to ensure patient care was maintained. In this article, we share a service evaluation and experiences dealing with the crisis through using a virtual office approach w... | covid-19;coronavirus;e-dentistry;pandemic;teledentistry;video consultations;videoconferencing | Journal Article | Crawford, Elizabeth;Taylor, Nigel | 10.1177/1465312520949557 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The effective use of an e-dentistry service during the COVID-19 crisis. [Abstract]: In 2020, we experienced the largest disruption to normal life recorded in recent years with the COVID-19 global pandemic. Creative thinking was required to ensure patient care was maintained. In this article, we share a service... |
32,360,300 | Virus Res | Natural product-derived phytochemicals as potential agents against coronaviruses: A review. | Coronaviruses are responsible for a growing economic, social and mortality burden, as the causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), avian infectious bronchitis virus (IBV) and COVID-19. However, there is a lack of effective antiviral agents fo... | covid-19;coronaviridae;middle east respiratory syndrome (mers);sars-cov-2;severe acute respiratory syndrome (sars);traditional medicine | Journal Article;Review | Mani, Janice S;Johnson, Joel B;Steel, Jason C;Broszczak, Daniel A;Neilsen, Paul M;Walsh, Kerry B;Naiker, Mani | 10.1016/j.virusres.2020.197989 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Natural product-derived phytochemicals as potential agents against coronaviruses: A review. [Abstract]: Coronaviruses are responsible for a growing economic, social and mortality burden, as the causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS)... |
33,004,978 | Sci Rep | Designing a multi-epitope peptide based vaccine against SARS-CoV-2. | COVID-19 pandemic has resulted in 16,114,449 cases with 646,641 deaths from the 217 countries, or territories as on July 27th 2020. Due to multifaceted issues and challenges in the implementation of the safety and preventive measures, inconsistent coordination between societies-governments and most importantly lack of ... | Journal Article | Singh, Abhishek;Thakur, Mukesh;Sharma, Lalit Kumar;Chandra, Kailash | 10.1038/s41598-020-73371-y | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Designing a multi-epitope peptide based vaccine against SARS-CoV-2. [Abstract]: COVID-19 pandemic has resulted in 16,114,449 cases with 646,641 deaths from the 217 countries, or territories as on July 27th 2020. Due to multifaceted issues and challenges in the implementation of the safety and preventive measur... | |
32,785,570 | Clinics (Sao Paulo) | Diagnostic Characteristics of Serological-Based COVID-19 Testing: A Systematic Review and Meta-Analysis. | Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promises to assist in assessing exposure to and confirming the diagnosis of coronavirus disease 2019 (COVID-19), and to provide a roadmap for reopening countries worldwide. Considering this, a proper understanding of serologic-based diag... | Journal Article;Meta-Analysis;Systematic Review | Moura, Diogo Turiani Hourneaux de;McCarty, Thomas R;Ribeiro, Igor Braga;Funari, Mateus Pereira;Oliveira, Pedro Victor Aniz Gomes de;Miranda Neto, Antonio Afonso de;Monte Junior, Epifanio Silvino do;Tustumi, Francisco;Bernardo, Wanderley Marques;Moura, Eduardo Guimaraes Hourneaux de;Thompson, Christopher C | 10.6061/clinics/2020/e2212 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Diagnostic Characteristics of Serological-Based COVID-19 Testing: A Systematic Review and Meta-Analysis. [Abstract]: Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promises to assist in assessing exposure to and confirming the diagnosis of coronavirus disease 2019 (COVID-19)... | |
32,357,378 | Head Neck | Ethical surgical triage of patients with head and neck cancer during the COVID-19 pandemic. | BACKGROUND: Coronavirus has serially overtaken our metropolitan hospitals. At peak, patients with acute respiratory distress syndrome may outnumber mechanical ventilators. In our Miami Hospital System, COVID-19 cases have multiplied for 4 weeks and elective surgery has been suspended. METHODS: An Otolaryngologic Triage... | Journal Article;Review | Civantos, Francisco J;Leibowitz, Jason M;Arnold, David J;Stubbs, Vanessa C;Gross, Jennifer H;Thomas, Giovana R;Sargi, Zoukaa;Casiano, Roy R;Franzmann, Elizabeth J;Weed, Donald;Perez, Cesar;Samuels, Michael;Goodman, Kenneth W;Goodwin, W Jarrard | 10.1002/hed.26229 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Ethical surgical triage of patients with head and neck cancer during the COVID-19 pandemic. [Abstract]: BACKGROUND: Coronavirus has serially overtaken our metropolitan hospitals. At peak, patients with acute respiratory distress syndrome may outnumber mechanical ventilators. In our Miami Hospital System, COVID... | |
32,640,274 | Genomics | SARS-CoV2 envelope protein: non-synonymous mutations and its consequences. | In the NCBI database, as on June 6, 2020, total number of available complete genome sequences of SARS-CoV2 across the world is 3617. The envelope (E) protein of SARS-CoV2 possesses several non-synonymous mutations over the transmembrane and C-terminus domains in 15 (0.414%) genomes among 3617 SARS-CoV2 genomes, analyze... | covid-19;envelope protein;non-synonymous mutations;sars-cov2 | Journal Article | Hassan, Sk Sarif;Choudhury, Pabitra Pal;Roy, Bidyut | 10.1016/j.ygeno.2020.07.001 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: SARS-CoV2 envelope protein: non-synonymous mutations and its consequences. [Abstract]: In the NCBI database, as on June 6, 2020, total number of available complete genome sequences of SARS-CoV2 across the world is 3617. The envelope (E) protein of SARS-CoV2 possesses several non-synonymous mutations over the t... |
32,763,888 | JMIR Public Health Surveill | COVID-19 in India: Statewise Analysis and Prediction. | BACKGROUND: The highly infectious coronavirus disease (COVID-19) was first detected in Wuhan, China in December 2019 and subsequently spread to 212 countries and territories around the world, infecting millions of people. In India, a large country of about 1.3 billion people, the disease was first detected on January 3... | 30-day prediction;covid-19;sis model;daily infection rate;disease modeling;exponential model;logistic model | Journal Article | Ghosh, Palash;Ghosh, Rik;Chakraborty, Bibhas | 10.2196/20341 | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: COVID-19 in India: Statewise Analysis and Prediction. [Abstract]: BACKGROUND: The highly infectious coronavirus disease (COVID-19) was first detected in Wuhan, China in December 2019 and subsequently spread to 212 countries and territories around the world, infecting millions of people. In India, a large count... |
32,776,725 | J Korean Med Sci | Viral Load Kinetics of SARS-CoV-2 Infection in Saliva in Korean Patients: a Prospective Multi-center Comparative Study. | BACKGROUND: This study was performed to compare the viral load and kinetics of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in saliva with those in standard nasopharyngeal/oropharyngeal (NP/OP) swabs. METHODS: Fifteen patients with SARS-CoV-2 infection from four hospitals were prospectively enrolled and... | nasopharyngeal swab;oropharyngeal swab;sars-cov-2 pcr;saliva | Journal Article | Kim, Seong Eun;Lee, Ji Yeon;Lee, Ahrang;Kim, Soosung;Park, Kyung Hwa;Jung, Sook In;Kang, Seung Ji;Oh, Tae Hoon;Kim, Uh Jin;Lee, Seung Yeob;Kee, Seung Jung;Jang, Hee Chang | 10.3346/jkms.2020.35.e287 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Viral Load Kinetics of SARS-CoV-2 Infection in Saliva in Korean Patients: a Prospective Multi-center Comparative Study. [Abstract]: BACKGROUND: This study was performed to compare the viral load and kinetics of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in saliva with those in standard nasoph... |
32,711,871 | Gac Sanit | [Review of new evidence about the possible vertical transmission of coronavirus disease-2019]. | OBJECTIVE: To conduct a systematic review of original peer-reviewed studies, containing data on the identification of SARS-CoV-2 in clinical samples of amniotic fluid, placenta or membranes, umbilical cord blood, and human milk, from women with a clinically or confirmed diagnosis of COVID-19. These studies should have ... | sars-cov-2;transmision vertical;vertical transmission | English Abstract;Journal Article;Review | Sampieri, Clara Luz;Montero, Hilda | 10.1016/j.gaceta.2020.06.005 | [
0,
0,
0,
0,
1,
0,
0
] | [Title]: [Review of new evidence about the possible vertical transmission of coronavirus disease-2019]. [Abstract]: OBJECTIVE: To conduct a systematic review of original peer-reviewed studies, containing data on the identification of SARS-CoV-2 in clinical samples of amniotic fluid, placenta or membranes, umbilical cor... |
33,015,519 | Health Equity | COVID-19: The Additional Sentence for the Incarcerated. | Incarcerated people are one of the most vulnerable populations during the coronavirus pandemic. There are varying perspectives regarding how to address the health care barriers seen in this population. Some individuals and organizations advocate for a mandatory release of the incarcerated who are not deemed a risk to t... | covid;disparity;incarcerated;jail;prison | Journal Article | Otugo, Onyeka;Wages, Brooke | 10.1089/heq.2020.0017 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19: The Additional Sentence for the Incarcerated. [Abstract]: Incarcerated people are one of the most vulnerable populations during the coronavirus pandemic. There are varying perspectives regarding how to address the health care barriers seen in this population. Some individuals and organizations advoca... |
32,301,279 | EMBO Mol Med | The prospects for the SARS-CoV-2 pandemic in Africa. | On December 31, 2019, the Chinese government officially announced the identification of a new type of coronavirus (SARS-CoV-2) as the etiological cause of a severe acute respiratory syndrome in Wuhan city, Hubei Province. Over the next weeks, SARS-CoV-2 caused a global pandemic as officially declared by the WHO on Marc... | Journal Article | Quaresima, Virginia;Naldini, Matteo M;Cirillo, Daniela M | 10.15252/emmm.202012488 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The prospects for the SARS-CoV-2 pandemic in Africa. [Abstract]: On December 31, 2019, the Chinese government officially announced the identification of a new type of coronavirus (SARS-CoV-2) as the etiological cause of a severe acute respiratory syndrome in Wuhan city, Hubei Province. Over the next weeks, SAR... | |
33,052,873 | JMIR Public Health Surveill | Evaluating the Need for Routine COVID-19 Testing of Emergency Department Staff: Quantitative Analysis. | BACKGROUND: As the number of COVID-19 cases in the US continues to increase and hospitals experience shortage of personal protective equipment (PPE), health care workers have been disproportionately affected. However, since COVID-19 testing is now easily available, there is a need to evaluate whether routine testing sh... | covid-19;diseases;emergency medicine;health policy;healthcare;infectious;modeling;policy;screening tests;surveillance screening | Evaluation Study;Journal Article | Zhang, Yuemei;Cheng, Sheng-Ru | 10.2196/20260 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: Evaluating the Need for Routine COVID-19 Testing of Emergency Department Staff: Quantitative Analysis. [Abstract]: BACKGROUND: As the number of COVID-19 cases in the US continues to increase and hospitals experience shortage of personal protective equipment (PPE), health care workers have been disproportionate... |
32,968,776 | Eur Heart J | Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study. | AIMS: Coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been associated with cardiovascular features of myocardial involvement including elevated serum troponin levels and acute heart failure with reduced ejection fraction. The cardiac pathological changes in th... | autopsy;covid-19;heart;macrophages;myocarditis;myocardium;sars;sars-cov-2 | Journal Article;Multicenter Study | Basso, Cristina;Leone, Ornella;Rizzo, Stefania;De Gaspari, Monica;van der Wal, Allard C;Aubry, Marie-Christine;Bois, Melanie C;Lin, Peter T;Maleszewski, Joseph J;Stone, James R | 10.1093/eurheartj/ehaa664 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study. [Abstract]: AIMS: Coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been associated with cardiovascular features of myocardial involvement incl... |
32,698,693 | J Biomol Struct Dyn | Dual inhibitors of SARS-CoV-2 proteases: pharmacophore and molecular dynamics based drug repositioning and phytochemical leads. | SARS-related coronaviruses poses continual threat to humanity by rapidly mutating and emerging as severe pandemic outbreaks, including the current nCoV-19 pandemic. Hence a rapid drug repositioning and lead identification strategy are required to mitigate these outbreaks. We report a pharmacophore and molecular dynamic... | 3cl-protease;pl-protease;pharmacophore;sars-cov-2 inhibitors;anti-hiv drugs;molecular dynamics;natural products;protease inhibitors | Journal Article | Mitra, Kartik;Ghanta, Prasanth;Acharya, Sushank;Chakrapani, Gayathri;Ramaiah, Basavaraju;Doble, Mukesh | 10.1080/07391102.2020.1796802 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Dual inhibitors of SARS-CoV-2 proteases: pharmacophore and molecular dynamics based drug repositioning and phytochemical leads. [Abstract]: SARS-related coronaviruses poses continual threat to humanity by rapidly mutating and emerging as severe pandemic outbreaks, including the current nCoV-19 pandemic. Hence ... |
33,078,076 | J Intensive Care | Factors influencing liberation from mechanical ventilation in coronavirus disease 2019: multicenter observational study in fifteen Italian ICUs. | Background: A large proportion of patients with coronavirus disease 2019 (COVID-19) develop severe respiratory failure requiring admission to the intensive care unit (ICU) and about 80% of them need mechanical ventilation (MV). These patients show great complexity due to multiple organ involvement and a dynamic evoluti... | ards;coronavirus disease 2019;intensive care;mechanical ventilation;outcomes, mortality;respiration, artificial | Journal Article | Gamberini, Lorenzo;Tonetti, Tommaso;Spadaro, Savino;Zani, Gianluca;Mazzoli, Carlo Alberto;Capozzi, Chiara;Giampalma, Emanuela;Bacchi Reggiani, Maria Letizia;Bertellini, Elisabetta;Castelli, Andrea;Cavalli, Irene;Colombo, Davide;Crimaldi, Federico;Damiani, Federica;Fogagnolo, Alberto;Fusari, Maurizio;Gamberini, Emiliano... | 10.1186/s40560-020-00499-4 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Factors influencing liberation from mechanical ventilation in coronavirus disease 2019: multicenter observational study in fifteen Italian ICUs. [Abstract]: Background: A large proportion of patients with coronavirus disease 2019 (COVID-19) develop severe respiratory failure requiring admission to the intensiv... |
32,406,317 | J Biomol Struct Dyn | Potential anti-viral activity of approved repurposed drug against main protease of SARS-CoV-2: an in silico based approach. | The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan province of China, has become a deadly pandemic causing alarmingly high morbidity and mortality. In the absence of new targeted drugs and vaccines against SARS-CoV-2 at present, the choices for effective treatments are li... | covid-19;fda approved drugs;mpro;sars-cov-2;docking;molecular dynamics;viomycin | Letter | Mahanta, Saurov;Chowdhury, Purvita;Gogoi, Neelutpal;Goswami, Nabajyoti;Borah, Debajit;Kumar, Rupesh;Chetia, Dipak;Borah, Probodh;Buragohain, Alak K;Gogoi, Bhaskarjyoti | 10.1080/07391102.2020.1768902 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Potential anti-viral activity of approved repurposed drug against main protease of SARS-CoV-2: an in silico based approach. [Abstract]: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan province of China, has become a deadly pandemic causing alarmingly high morb... |
32,820,077 | Proc Natl Acad Sci U S A | Demographic perspectives on the mortality of COVID-19 and other epidemics. | To put estimates of COVID-19 mortality into perspective, we estimate age-specific mortality for an epidemic claiming for illustrative purposes 1 million US lives, with results approximately scalable over a broad range of deaths. We calculate the impact on period life expectancy (down 2.94 y) and remaining life years (1... | covid-19;demography;epidemic;life expectancy;mortality | Comparative Study;Historical Article;Journal Article;Research Support, N.I.H., Extramural | Goldstein, Joshua R;Lee, Ronald D | 10.1073/pnas.2006392117 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Demographic perspectives on the mortality of COVID-19 and other epidemics. [Abstract]: To put estimates of COVID-19 mortality into perspective, we estimate age-specific mortality for an epidemic claiming for illustrative purposes 1 million US lives, with results approximately scalable over a broad range of dea... |
32,054,787 | Proc Natl Acad Sci U S A | Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. | The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high case fatality rate stresses the need for the availability of effective antiviral treatments. Remdesivir (GS-5734) effectively inhibited MERS coronavirus (MERS-CoV) replication in vitro, and showed efficacy against Severe Acute Respirat... | mers-cov;animal model;antiviral;remdesivir;therapy | Journal Article;Research Support, N.I.H., Intramural | de Wit, Emmie;Feldmann, Friederike;Cronin, Jacqueline;Jordan, Robert;Okumura, Atsushi;Thomas, Tina;Scott, Dana;Cihlar, Tomas;Feldmann, Heinz | 10.1073/pnas.1922083117 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. [Abstract]: The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high case fatality rate stresses the need for the availability of effective antiviral treatments. Remdesivir... |
32,340,531 | J Prim Care Community Health | Increasing the Signal-to-Noise Ratio: COVID-19 Clinical Synopsis for Outpatient Providers. | The novel coronavirus (SARS-CoV-2), which is the cause of coronavirus disease (COVID-19 formally 2019-nCoV), has received widespread attention from the medical community. Despite the rapid publication of research on the virus and the disease it causes, there is a lack of concise and relevant material to help busy medic... | covid-19;outpatients;severe acute respiratory syndrome coronavirus 2 | Journal Article;Review | Sartor, Zach;Hess, Burritt | 10.1177/2150132720922957 | [
1,
1,
1,
1,
1,
0,
0
] | [Title]: Increasing the Signal-to-Noise Ratio: COVID-19 Clinical Synopsis for Outpatient Providers. [Abstract]: The novel coronavirus (SARS-CoV-2), which is the cause of coronavirus disease (COVID-19 formally 2019-nCoV), has received widespread attention from the medical community. Despite the rapid publication of rese... |
32,396,447 | Glob Public Health | Protecting health during COVID-19 and beyond: A global examination of paid sick leave design in 193 countries. | Well-designed paid sick leave is critical to ensure workers stay home when sick to prevent the spread of SARS-CoV-2 and other infectious pathogens, both when the economy is open and during an economic shutdown. To assess whether paid sick leave is available in countries around the world, we created and analysed a datab... | covid-19;global policy analysis;infectious disease spread;paid sick leave;workplace | Journal Article;Research Support, Non-U.S. Gov't;Video-Audio Media | Heymann, Jody;Raub, Amy;Waisath, Willetta;McCormack, Michael;Weistroffer, Ross;Moreno, Gonzalo;Wong, Elizabeth;Earle, Alison | 10.1080/17441692.2020.1764076 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Protecting health during COVID-19 and beyond: A global examination of paid sick leave design in 193 countries. [Abstract]: Well-designed paid sick leave is critical to ensure workers stay home when sick to prevent the spread of SARS-CoV-2 and other infectious pathogens, both when the economy is open and during... |
33,050,885 | BMC Anesthesiol | Anesthesia departments' readiness for the COVID-19 pandemic; a nationwide cross-sectional study in Israel. | BACKGROUND: The Coronavirus infectious disease 2019 (COVID-19) brings anesthesiologists and intensive care physicians to the mainstay of clinical workload and healthcare managements' focus. There are approximately 900 anesthesiologists in Israel, working in non-private hospitals. This nationwide cross-sectional study e... | anesthesia department;covid-19;crisis management;cross-sectional;israel | Journal Article | Cohen, Barak;Baar, Yuval;Fein, Shai;Matot, Idit | 10.1186/s12871-020-01173-w | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Anesthesia departments' readiness for the COVID-19 pandemic; a nationwide cross-sectional study in Israel. [Abstract]: BACKGROUND: The Coronavirus infectious disease 2019 (COVID-19) brings anesthesiologists and intensive care physicians to the mainstay of clinical workload and healthcare managements' focus. Th... |
32,980,489 | J Hosp Infect | Natural history of SARS-CoV-2 infection in healthcare workers in Northern Italy. | At present, the time-frame used for the quarantine of individuals with coronavirus disease 2019 (COVID-19) is the entire duration of symptoms plus 14 days after symptom recovery; however, no data have been reported specifically for healthcare workers (HCWs). In the study population of 142 HCWs with COVID-19, the mean t... | Journal Article | Bongiovanni, M;Marra, A M;De Lauretis, A;Bini, F;Di Carlo, D;Manes, G;Bodini, B D;Pellegrini, L;Schettino, M;Picascia, D;Bellini, A | 10.1016/j.jhin.2020.08.027 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Natural history of SARS-CoV-2 infection in healthcare workers in Northern Italy. [Abstract]: At present, the time-frame used for the quarantine of individuals with coronavirus disease 2019 (COVID-19) is the entire duration of symptoms plus 14 days after symptom recovery; however, no data have been reported spe... | |
32,989,044 | RNA | Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. | Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. In this study, we used mouse hepatitis virus (MHV)-infected bone marrow-derived macrophage (BMM) and cyclic phosphate cDNA sequencing to identify the RNA targets of EndoU. EndoU targeted viral R... | coronavirus;dsrna;endoribonuclease;innate immunity;mouse hepatitis virus | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Ancar, Rachel;Li, Yize;Kindler, Eveline;Cooper, Daphne A;Ransom, Monica;Thiel, Volker;Weiss, Susan R;Hesselberth, Jay R;Barton, David J | 10.1261/rna.076604.120 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. [Abstract]: Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. In this study, we used mouse hepatitis virus (MHV)-infected bone marrow-derived macrophage (BM... |
32,750,004 | J Med Internet Res | Influence of Social Media Platforms on Public Health Protection Against the COVID-19 Pandemic via the Mediating Effects of Public Health Awareness and Behavioral Changes: Integrated Model. | BACKGROUND: Despite the growing body of literature examining social media in health contexts, including public health communication, promotion, and surveillance, limited insight has been provided into how the utility of social media may vary depending on the particular public health objectives governing an intervention... | covid-19;interventions;jordan;awareness;behavior;behavioral change;coronavirus;pandemic;public health;public health protection;social media;social media platforms | Journal Article | Al-Dmour, Hani;Masa'deh, Ra'ed;Salman, Amer;Abuhashesh, Mohammad;Al-Dmour, Rand | 10.2196/19996 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Influence of Social Media Platforms on Public Health Protection Against the COVID-19 Pandemic via the Mediating Effects of Public Health Awareness and Behavioral Changes: Integrated Model. [Abstract]: BACKGROUND: Despite the growing body of literature examining social media in health contexts, including public... |
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