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32,433,389
J Public Health Manag Pract
American Indian Reservations and COVID-19: Correlates of Early Infection Rates in the Pandemic.
OBJECTIVE: To determine the household and community characteristics most closely associated with variation in COVID-19 incidence on American Indian reservations in the lower 48 states. DESIGN: Multivariate analysis with population weights. SETTING: Two hundred eighty-seven American Indian Reservations and tribal homela...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, P.H.S.
Rodriguez-Lonebear, Desi;Barcelo, Nicolas E;Akee, Randall;Carroll, Stephanie Russo
10.1097/PHH.0000000000001206
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: American Indian Reservations and COVID-19: Correlates of Early Infection Rates in the Pandemic. [Abstract]: OBJECTIVE: To determine the household and community characteristics most closely associated with variation in COVID-19 incidence on American Indian reservations in the lower 48 states. DESIGN: Multivaria...
32,845,720
Am J Physiol Cell Physiol
Rho GTPases and the emerging role of tunneling nanotubes in physiology and disease.
Tunneling nanotubes (TNTs) emerged as important specialized actin-rich membrane protrusions for cell-to-cell communication. These structures allow the intercellular exchange of material, such as ions, soluble proteins, receptors, vesicles and organelles, therefore exerting critical roles in normal cell function. Indeed...
rho gtpases;sars-cov-2;actin cytoskeleton;tunneling nanotubes;virus transmission
Journal Article;Research Support, N.I.H., Extramural
Zhang, Suli;Kazanietz, Marcelo G;Cooke, Mariana
10.1152/ajpcell.00351.2020
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Rho GTPases and the emerging role of tunneling nanotubes in physiology and disease. [Abstract]: Tunneling nanotubes (TNTs) emerged as important specialized actin-rich membrane protrusions for cell-to-cell communication. These structures allow the intercellular exchange of material, such as ions, soluble protei...
32,420,924
Acta Biomed
Impact of the COVID-19 epidemic on census, organization and activity of a large urban Emergency Department.
BACKGROUND: The spread of coronavirus disease 2019 (COVID-19) is overwhelming the response of many regional health services across Italy. This article aims to report and discuss the data of the first 8 weeks of COVID-19 epidemic in the emergency department (ED) of the University Hospital of Parma. METHODS: The ED visit...
Journal Article
Comelli, Ivan;Scioscioli, Francesco;Cervellin, Gianfranco
10.23750/abm.v91i2.9565
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of the COVID-19 epidemic on census, organization and activity of a large urban Emergency Department. [Abstract]: BACKGROUND: The spread of coronavirus disease 2019 (COVID-19) is overwhelming the response of many regional health services across Italy. This article aims to report and discuss the data of t...
32,682,084
Neural Netw
Towards explainable deep neural networks (xDNN).
In this paper, we propose an elegant solution that is directly addressing the bottlenecks of the traditional deep learning approaches and offers an explainable internal architecture that can outperform the existing methods, requires very little computational resources (no need for GPUs) and short training times (in the...
deep-learning;explainable ai;interpretability;prototype-based models
Journal Article
Angelov, Plamen;Soares, Eduardo
10.1016/j.neunet.2020.07.010
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Towards explainable deep neural networks (xDNN). [Abstract]: In this paper, we propose an elegant solution that is directly addressing the bottlenecks of the traditional deep learning approaches and offers an explainable internal architecture that can outperform the existing methods, requires very little compu...
32,984,405
Front Cardiovasc Med
The Dual Role of Echocardiography in the Diagnosis of Acute Cardiac Complications and Treatment Monitoring for Coronavirus Disease 2019 (COVID-19).
The Coronavirus Disease 2019 (COVID-19) pandemic, being caused by an easily and rapidly spreading novel betacoronavirus, has created a state of emergency for people, the scientific community, healthcare systems and states, while the global financial consequences are still unfolding. Cardiovascular complications have be...
coronavirus disease 2019;sars-cov 2;anti-inflammatory treatment;antiviral treatment;coronavirus;global longitudinal strain;transthoracic echo
Journal Article
Vrettou, Agathi-Rosa;Parissis, John;Ikonomidis, Ignatios
10.3389/fcvm.2020.00129
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The Dual Role of Echocardiography in the Diagnosis of Acute Cardiac Complications and Treatment Monitoring for Coronavirus Disease 2019 (COVID-19). [Abstract]: The Coronavirus Disease 2019 (COVID-19) pandemic, being caused by an easily and rapidly spreading novel betacoronavirus, has created a state of emergen...
32,924,960
JMIR Res Protoc
Peer-to-Peer Health Communication in Older Adults' Online Communities: Protocol for a Qualitative Netnographic Study and Co-Design Approach.
BACKGROUND: Online communities provide an environment in which people with similar health concerns can interact and access content that can support the self-management of long-term conditions (LTCs). Recently, the importance of online social networks as sources of health information and social support has been brought ...
covid-19;aged;chronic illness and disease;co-design;long-term conditions;netnography;online community;peer support;self-management;social media
Journal Article
Lawless, Michael Thomas;Archibald, Mandy;Pinero de Plaza, Maria Alejandra;Drioli-Phillips, Phoebe;Kitson, Alison
10.2196/19834
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Peer-to-Peer Health Communication in Older Adults' Online Communities: Protocol for a Qualitative Netnographic Study and Co-Design Approach. [Abstract]: BACKGROUND: Online communities provide an environment in which people with similar health concerns can interact and access content that can support the self-m...
32,397,688
Viruses
SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions.
The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic infections to mild respiratory symptoms to the lethal form of COVID-19 which is associated with severe pneumonia, acute respiratory distress, and fat...
covid-19;sars-cov-2;coronavirus;pandemic;viral genomics
Journal Article;Review
Uddin, Mohammed;Mustafa, Farah;Rizvi, Tahir A;Loney, Tom;Suwaidi, Hanan Al;Al-Marzouqi, Ahmed H Hassan;Eldin, Afaf Kamal;Alsabeeha, Nabeel;Adrian, Thomas E;Stefanini, Cesare;Nowotny, Norbert;Alsheikh-Ali, Alawi;Senok, Abiola C
10.3390/v12050526
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions. [Abstract]: The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic infections to mild respiratory sympt...
32,819,896
AJNR Am J Neuroradiol
COVID-19-Associated Carotid Atherothrombosis and Stroke.
We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COVID-associated carotid atherothrombosis.
Journal Article
Esenwa, C;Cheng, N T;Lipsitz, E;Hsu, K;Zampolin, R;Gersten, A;Antoniello, D;Soetanto, A;Kirchoff, K;Liberman, A;Mabie, P;Nisar, T;Rahimian, D;Brook, A;Lee, S-K;Haranhalli, N;Altschul, D;Labovitz, D
10.3174/ajnr.A6752
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19-Associated Carotid Atherothrombosis and Stroke. [Abstract]: We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COV...
32,791,552
Dtsch Med Wochenschr
[COVID-19 and the impact of cardiovascular comorbidities].
Since its outbreak, coronavirus disease 2019 (COVID-19) has rapidly resulted in a global pandemic. Underlying cardiovascular disease (CVD) is associated with severe COVID-19 infection and adverse clinical outcomes. While COVID-19 predominantly causes respiratory symptoms, a substantial number of patients eventually dev...
Journal Article
Seoudy, Hatim;Frey, Norbert
10.1055/a-1158-5996
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [COVID-19 and the impact of cardiovascular comorbidities]. [Abstract]: Since its outbreak, coronavirus disease 2019 (COVID-19) has rapidly resulted in a global pandemic. Underlying cardiovascular disease (CVD) is associated with severe COVID-19 infection and adverse clinical outcomes. While COVID-19 predominan...
32,384,004
J Palliat Med
Systems Barriers to Assessment and Treatment of COVID-19 Positive Patients at the End of Life.
The Novel Coronavirus SARS-CoV-2 (COVID-19) pandemic is changing how we deliver expert palliative care. We can expect many to die prematurely secondary to COVID-19 across the United States. We present a case of how several hospital systems-based interventions, intended to slow viral spread and to protect health care wo...
covid-19;palliative care;patient isolation;symptom assessment;symptom management;system barriers
Case Reports;Journal Article
Pahuja, Meera;Wojcikewych, Devon
10.1089/jpm.2020.0190
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Systems Barriers to Assessment and Treatment of COVID-19 Positive Patients at the End of Life. [Abstract]: The Novel Coronavirus SARS-CoV-2 (COVID-19) pandemic is changing how we deliver expert palliative care. We can expect many to die prematurely secondary to COVID-19 across the United States. We present a c...
32,787,822
BMC Med Res Methodol
Disease progression of cancer patients during COVID-19 pandemic: a comprehensive analytical strategy by time-dependent modelling.
BACKGROUND: As the whole world is experiencing the cascading effect of a new pandemic, almost every aspect of modern life has been disrupted. Because of health emergencies during this period, widespread fear has resulted in compromised patient safety, especially for patients with cancer. It is very challenging to treat...
accelerated failure time;auto-regression;bayesian;covid-19;proportional hazard model
Journal Article;Research Support, Non-U.S. Gov't
Bhattacharjee, Atanu;Vishwakarma, Gajendra K;Banerjee, Souvik;Shukla, Sharvari
10.1186/s12874-020-01090-z
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Disease progression of cancer patients during COVID-19 pandemic: a comprehensive analytical strategy by time-dependent modelling. [Abstract]: BACKGROUND: As the whole world is experiencing the cascading effect of a new pandemic, almost every aspect of modern life has been disrupted. Because of health emergenci...
32,407,062
Minerva Stomatol
COVID-19: how to decrease the risk of infection in dental practice?
A new pandemic classified by the World Health Organization and called COVID-19, is causing widespread respiratory infections and deaths in several countries on the five continents. Although it does not have a high lethality rate, this new virus can present rates of complications and hospitalizations in the intensive ca...
Journal Article;Review
da Hora Sale S, Pedro H;Lopes de Gusmao Sales, Priscila;da Hora Sales, Maria L
10.23736/S0026-4970.20.04372-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: how to decrease the risk of infection in dental practice? [Abstract]: A new pandemic classified by the World Health Organization and called COVID-19, is causing widespread respiratory infections and deaths in several countries on the five continents. Although it does not have a high lethality rate, t...
32,228,322
Am J Physiol Endocrinol Metab
COVID-19 pandemic, coronaviruses, and diabetes mellitus.
The pandemic of coronavirus disease (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID...
covid-19;coronavirus;diabetes mellitus
Journal Article;Research Support, N.I.H., Intramural
Muniyappa, Ranganath;Gubbi, Sriram
10.1152/ajpendo.00124.2020
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 pandemic, coronaviruses, and diabetes mellitus. [Abstract]: The pandemic of coronavirus disease (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and o...
32,670,091
Front Physiol
The Modulation of Mucosal Antiviral Immunity by Immunobiotics: Could They Offer Any Benefit in the SARS-CoV-2 Pandemic?
Viral respiratory infections are of major importance because of their capacity to cause of a high degree of morbidity and mortality in high-risk populations, and to rapidly spread between countries. Perhaps the best example of this global threat is the infectious disease caused by the new SARS-CoV-2 virus, which has in...
beneficial microbes;coronavirus;immunobiotics;inflammation;respiratory viral infections
Journal Article;Review
Villena, Julio;Kitazawa, Haruki
10.3389/fphys.2020.00699
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Modulation of Mucosal Antiviral Immunity by Immunobiotics: Could They Offer Any Benefit in the SARS-CoV-2 Pandemic? [Abstract]: Viral respiratory infections are of major importance because of their capacity to cause of a high degree of morbidity and mortality in high-risk populations, and to rapidly spread...
32,452,819
JMIR Public Health Surveill
Primary Health Care Facility Preparedness for Outpatient Service Provision During the COVID-19 Pandemic in India: Cross-Sectional Study.
BACKGROUND: Primary health centers (PHCs) represent the first tier of the Indian health care system, providing a range of essential outpatient services to people living in the rural, suburban, and hard-to-reach areas. Diversion of health care resources for containing the coronavirus disease (COVID-19) pandemic has sign...
covid-19;india;health systems;pandemic;primary health care
Journal Article
Garg, Suneela;Basu, Saurav;Rustagi, Ruchir;Borle, Amod
10.2196/19927
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Primary Health Care Facility Preparedness for Outpatient Service Provision During the COVID-19 Pandemic in India: Cross-Sectional Study. [Abstract]: BACKGROUND: Primary health centers (PHCs) represent the first tier of the Indian health care system, providing a range of essential outpatient services to people ...
32,825,295
Cancers (Basel)
Low Incidence of SARS-CoV-2 in Patients with Solid Tumours on Active Treatment: An Observational Study at a Tertiary Cancer Centre in Lombardy, Italy.
Background: The incidence and prognosis of SARS-CoV-2-positive cancer patients on active oncologic treatment remain unknown. Retrospective data from China reported higher incidence and poorer outcomes with respect to the general population. We aimed to describe the real-word incidence of SARS-CoV-2 in cancer patients a...
covid-19;sars-cov-2;cancer care;chemotherapy;immunotherapy;treatment safety
Journal Article
Bertuzzi, Alexia Francesca;Marrari, Andrea;Gennaro, Nicolo;Cariboni, Umberto;Ciccarelli, Michele;Giordano, Laura;Quagliuolo, Vittorio Lorenzo;Santoro, Armando
10.3390/cancers12092352
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Low Incidence of SARS-CoV-2 in Patients with Solid Tumours on Active Treatment: An Observational Study at a Tertiary Cancer Centre in Lombardy, Italy. [Abstract]: Background: The incidence and prognosis of SARS-CoV-2-positive cancer patients on active oncologic treatment remain unknown. Retrospective data from...
32,482,587
Res Social Adm Pharm
Time-trend analysis of medicine sales and shortages during COVID-19 outbreak: Data from community pharmacies.
BACKGROUND: COVID-19 is a worldwide public health concern. Disruptions in the drug market are expected and shortages might worsen. Community pharmacies can contribute to early identification and report of medicines' supply and demand issues. OBJECTIVE: The aim of this study is to characterize the impact of the COVID-19...
covid-19;demand;medicine;pharmacies;shortages
Journal Article
Romano, Sonia;Galante, Heloisa;Figueira, Debora;Mendes, Zilda;Rodrigues, Antonio Teixeira
10.1016/j.sapharm.2020.05.024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Time-trend analysis of medicine sales and shortages during COVID-19 outbreak: Data from community pharmacies. [Abstract]: BACKGROUND: COVID-19 is a worldwide public health concern. Disruptions in the drug market are expected and shortages might worsen. Community pharmacies can contribute to early identificatio...
32,887,660
Eur J Med Res
The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis.
BACKGROUND: Coronavirus is challenging the global health care system from time to time. The pregnant state, with alterations in hormone levels and decreased lung volumes due to a gravid uterus and slightly immunocompromised state may predispose patients to a more rapidly deteriorating clinical course and can get a grea...
coronavirus;infection;middle east respiratory syndrome;novel coronavirus-2019;pregnancy;severe acute respiratory syndrome;severe acute respiratory syndrome coronavirus-2;vertical transmission
Journal Article;Meta-Analysis;Systematic Review
Diriba, Kuma;Awulachew, Ephrem;Getu, Eyob
10.1186/s40001-020-00439-w
[ 1, 1, 0, 0, 1, 0, 0 ]
[Title]: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis. [Abstract]: BACKGROUND: Coronavirus is challenging the global health care system from time to time. The pregnant state, w...
32,950,975
Pharmacology
When Therapeutic IgA Antibodies Might Come of Age.
BACKGROUND: Extensive efforts have been made in optimizing monoclonal immunoglobulin (Ig)G antibodies for use in clinical practice. Accumulating evidence suggests that IgA or anti-FcalphaRI could also represent an exciting avenue toward novel therapeutic strategies. SUMMARY: Here, we underline that IgA is more effectiv...
bioengineering;immunoglobulin a;primary antibody deficiency;therapeutic antibody
Journal Article;Review
Sterlin, Delphine;Gorochov, Guy
10.1159/000510251
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: When Therapeutic IgA Antibodies Might Come of Age. [Abstract]: BACKGROUND: Extensive efforts have been made in optimizing monoclonal immunoglobulin (Ig)G antibodies for use in clinical practice. Accumulating evidence suggests that IgA or anti-FcalphaRI could also represent an exciting avenue toward novel thera...
32,531,948
Cancers (Basel)
A Guide for Oncologic Patient Management during Covid-19 Pandemic: The Initial Experience of an Italian Oncologic Hub with Exemplificative Focus on Uro-Oncologic Patients.
The recent exponential increase in the number of COVID-19 patients in Italy led to the adoption of specific extraordinary measures, such as the need to convey treatment of all non-deferrable cancer patients to specialized centres (hubs). We reported a comprehensive summary of guidelines to create and run an oncologic h...
covid-19;sars-cov-2;medical oncology;oncology service;surgical oncology
Journal Article
Mistretta, Francesco A;Luzzago, Stefano;Molendini, Luigi Orlando;Ferro, Matteo;Dossena, Enza;Mastrilli, Fabrizio;Musi, Gennaro;de Cobelli, Ottavio
10.3390/cancers12061513
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Guide for Oncologic Patient Management during Covid-19 Pandemic: The Initial Experience of an Italian Oncologic Hub with Exemplificative Focus on Uro-Oncologic Patients. [Abstract]: The recent exponential increase in the number of COVID-19 patients in Italy led to the adoption of specific extraordinary measu...
32,448,136
BMC Med Imaging
Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the new coronavirus. Previous studies have shown that the chest CT examination plays an important role in the diagnosis and monitoring of COVID-19. However, some patients with COVID-19 had low white blood cell counts and reduced ly...
covid-19;caredose 4d;image quality;radiation dose
Journal Article;Randomized Controlled Trial
Li, Jiawei;Wang, Xiao;Huang, Xiaolu;Chen, Fangxing;Zhang, Xuesong;Liu, Ying;Luo, Guangzuo;Xu, Xunhua
10.1186/s12880-020-00456-5
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the new coronavirus. Previous studies have shown that the chest CT examination play...
32,957,928
BMC Infect Dis
Epidemiological surveillance of common respiratory viruses in patients with suspected COVID-19 in Southwest China.
BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the peak season of common respiratory viral infections. However, the clinical symptoms of most SARS-CoV-2 infected patients are not significantly different from those o...
covid-19;respiratory viral pathogens;surveillance research
Journal Article
Si, Yanjun;Zhao, Zhenzhen;Chen, Rong;Zhong, Huiyu;Liu, Tangyuheng;Wang, Minjin;Song, Xingbo;Li, Weimin;Ying, Binwu
10.1186/s12879-020-05392-x
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Epidemiological surveillance of common respiratory viruses in patients with suspected COVID-19 in Southwest China. [Abstract]: BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the peak season of common respir...
33,076,875
BMC Public Health
Risk perception related to COVID-19 among the Iranian general population: an application of the extended parallel process model.
BACKGROUND: The novel coronavirus disease 2019 (COVID-19) has emerged as a major global public health challenge. This study aimed to investigate on how people perceive the COVID-19 outbreak using the components of the Extended Parallel Process Model (EPPM) and to find out how this might contribute to possible behaviora...
behavior response;coronavirus disease 2019;danger control;extended parallel process model;fear control
Journal Article
Jahangiry, Leila;Bakhtari, Fatemeh;Sohrabi, Zahara;Reihani, Parvin;Samei, Sirous;Ponnet, Koen;Montazeri, Ali
10.1186/s12889-020-09681-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Risk perception related to COVID-19 among the Iranian general population: an application of the extended parallel process model. [Abstract]: BACKGROUND: The novel coronavirus disease 2019 (COVID-19) has emerged as a major global public health challenge. This study aimed to investigate on how people perceive th...
32,165,541
Proc Natl Acad Sci U S A
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently spreading across many countries globally. Here, we show that a TMPRSS2-expressing VeroE6 cell line is highly susceptible to SARS-CoV-2 infection...
sars-cov-2;tmprss2;veroe6;coronavirus;outbreak
Journal Article;Research Support, Non-U.S. Gov't
Matsuyama, Shutoku;Nao, Naganori;Shirato, Kazuya;Kawase, Miyuki;Saito, Shinji;Takayama, Ikuyo;Nagata, Noriyo;Sekizuka, Tsuyoshi;Katoh, Hiroshi;Kato, Fumihiro;Sakata, Masafumi;Tahara, Maino;Kutsuna, Satoshi;Ohmagari, Norio;Kuroda, Makoto;Suzuki, Tadaki;Kageyama, Tsutomu;Takeda, Makoto
10.1073/pnas.2002589117
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells. [Abstract]: A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently spreading across many countries globally. Here, we show that ...
32,340,912
Radiography (Lond)
Management of patients with suspected or confirmed COVID-19, in the radiology department.
OBJECTIVES: From December 2019, a novel coronavirus disease named COVID-19 was reported in China. Within 3 months, the World Health Organization defined COVID-19 as a pandemic, with more than 370,000 cases and 16,000 deaths worldwide. In consideration of the crucial role of diagnostic testing during COVID-19, the aim o...
covid-19;coronavirus;infection control;radiography;tomography, x-ray computed
Journal Article;Review
Zanardo, M;Martini, C;Monti, C B;Cattaneo, F;Ciaralli, C;Cornacchione, P;Durante, S
10.1016/j.radi.2020.04.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of patients with suspected or confirmed COVID-19, in the radiology department. [Abstract]: OBJECTIVES: From December 2019, a novel coronavirus disease named COVID-19 was reported in China. Within 3 months, the World Health Organization defined COVID-19 as a pandemic, with more than 370,000 cases and...
33,071,304
Int Rev Educ
On the fly: Adapting quickly to emergency remote instruction in a family literacy programme.
The COVID-19 pandemic has led to extraordinary changes in family literacy instruction, forcing face-to-face programmes to shift rapidly (or "on the fly") to online, remote instruction. This study is one of the few on online teaching and learning in family literacy and, to the knowledge of the authors, the first on emer...
adult basic education;covid-19 pandemic;distance education;emergency remote instruction;emergency remote teaching;family literacy
Journal Article
Kaiper-Marquez, Anna;Wolfe, Emily;Clymer, Carol;Lee, Jungeun;McLean, Elisabeth Grinder;Prins, Esther;Stickel, Tabitha
10.1007/s11159-020-09861-y
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: On the fly: Adapting quickly to emergency remote instruction in a family literacy programme. [Abstract]: The COVID-19 pandemic has led to extraordinary changes in family literacy instruction, forcing face-to-face programmes to shift rapidly (or "on the fly") to online, remote instruction. This study is one of ...
32,615,871
United European Gastroenterol J
Endoscopy works during the pandemic of coronavirus COVID-19: recommendations by the Chinese Society of Digestive Endoscopy.
Since December 2019, a novel coronavirus disease, COVID-19, has occurred in China and has spread around the world rapidly. As an acute respiratory infectious disease, COVID-19 has been included in type B infectious diseases and managed according to the standard of type A infectious disease in China. Given the high risk...
endoscopy;colonoscopy;endoscopic ultrasound;epidemiology;surgery
Journal Article
Chai, Ningli;Mei, Zhechuan;Zhang, Wengang;Du, Chen;Wang, Xiangyao;Li, Longsong;Ma, Yan;Zou, Jiale;Tang, Xiaowei;Wang, Nanjun;Feng, Jiancong;Linghu, Enqiang
10.1177/2050640620930632
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Endoscopy works during the pandemic of coronavirus COVID-19: recommendations by the Chinese Society of Digestive Endoscopy. [Abstract]: Since December 2019, a novel coronavirus disease, COVID-19, has occurred in China and has spread around the world rapidly. As an acute respiratory infectious disease, COVID-19...
32,363,750
Mol Inform
A Chemographic Audit of anti-Coronavirus Structure-activity Information from Public Databases (ChEMBL).
Discovery of drugs against newly emerged pathogenic agents like the SARS-CoV-2 coronavirus (CoV) must be based on previous research against related species. Scientists need to get acquainted with and develop a global oversight over so-far tested molecules. Chemography (herein used Generative Topographic Mapping, in par...
antivirals;generative topographic mapping;sars;structure-activity relationships;chemography;coronavirus
Journal Article;Research Support, Non-U.S. Gov't
Horvath, Dragos;Orlov, Alexey;Osolodkin, Dmitry I;Ishmukhametov, Aydar A;Marcou, Gilles;Varnek, Alexandre
10.1002/minf.202000080
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Chemographic Audit of anti-Coronavirus Structure-activity Information from Public Databases (ChEMBL). [Abstract]: Discovery of drugs against newly emerged pathogenic agents like the SARS-CoV-2 coronavirus (CoV) must be based on previous research against related species. Scientists need to get acquainted with...
32,277,022
J Clin Microbiol
Clinical Evaluation of the cobas SARS-CoV-2 Test and a Diagnostic Platform Switch during 48 Hours in the Midst of the COVID-19 Pandemic.
Laboratories are currently witnessing extraordinary demand globally for sampling devices, reagents, consumables, and diagnostic instruments needed for timely diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. To meet diagnostic needs as the pandemic grows, the U.S. Food and Drug Admini...
covid-19;sars-cov-2;cobas;cobas 6800
Evaluation Study;Journal Article;Research Support, Non-U.S. Gov't
Poljak, Mario;Korva, Misa;Knap Gasper, Natasa;Fujs Komlos, Kristina;Sagadin, Martin;Ursic, Tina;Avsic Zupanc, Tatjana;Petrovec, Miroslav
10.1128/JCM.00599-20
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Evaluation of the cobas SARS-CoV-2 Test and a Diagnostic Platform Switch during 48 Hours in the Midst of the COVID-19 Pandemic. [Abstract]: Laboratories are currently witnessing extraordinary demand globally for sampling devices, reagents, consumables, and diagnostic instruments needed for timely diag...
33,033,429
Tob Use Insights
YES it's the Perfect Time to Quit: Fueling Tobacco Cessation in India during COVID-19 Pandemic.
Entire world is battling the Novel Coronavirus Disease (COVID-19) pandemic. India too, has undertaken stringent containment measures to combat this disease. The country is in a state of national lockdown, which has inadvertently led more than a quarter of the Indian population to not use tobacco. This paper discusses t...
tobacco cessation;pandemic;smokeless tobacco;smoking
Journal Article
Grover, Shekhar;Mohanty, Vikrant;Jain, Swati;Anand, Tanu;Aghi, Mira B
10.1177/1179173X20960447
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: YES it's the Perfect Time to Quit: Fueling Tobacco Cessation in India during COVID-19 Pandemic. [Abstract]: Entire world is battling the Novel Coronavirus Disease (COVID-19) pandemic. India too, has undertaken stringent containment measures to combat this disease. The country is in a state of national lockdown...
32,222,812
Intensive Care Med
Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).
BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people around the world. Urgent guidance for clinicians caring for the sickest of these patients is needed. METHODS: We formed a pan...
covid-19;clinical practice guidelines;coronavirus;critical illness;sars cov-2
Journal Article;Practice Guideline
Alhazzani, Waleed;Moller, Morten Hylander;Arabi, Yaseen M;Loeb, Mark;Gong, Michelle Ng;Fan, Eddy;Oczkowski, Simon;Levy, Mitchell M;Derde, Lennie;Dzierba, Amy;Du, Bin;Aboodi, Michael;Wunsch, Hannah;Cecconi, Maurizio;Koh, Younsuck;Chertow, Daniel S;Maitland, Kathryn;Alshamsi, Fayez;Belley-Cote, Emilie;Greco, Massimiliano...
10.1007/s00134-020-06022-5
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19). [Abstract]: BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting t...
32,793,973
Inflamm Bowel Dis
Worldwide Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: An International Survey.
BACKGROUND AND AIMS: Persons with inflammatory bowel disease (IBD) may be particularly vulnerable to COVID-19 either because of their underlying disease or its management. Guidance has been presented on the management of persons with IBD in the time of this pandemic by different groups. We aimed to determine how gastro...
covid-9;immunomodulatory therapy;inflammatory bowel disease;management;pandemic
Journal Article
Bernstein, Charles N;Ng, Siew C;Banerjee, Rupa;Steinwurz, Flavio;Shen, Bo;Carbonnel, Franck;Hamid, Saeed;Sood, Ajit;Yamamoto-Furusho, Jesus K;Griffiths, Anne;Benchimol, Eric I;Travis, Simon;Lopes, Susana;Rubin, David T;Kaplan, Gilaad G;Armstrong, David;Gearry, Richard
10.1093/ibd/izaa202
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Worldwide Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: An International Survey. [Abstract]: BACKGROUND AND AIMS: Persons with inflammatory bowel disease (IBD) may be particularly vulnerable to COVID-19 either because of their underlying disease or its management. Guidance has been pre...
33,058,800
Am J Cardiol
Usefulness of Elevated Troponin to Predict Death in Patients With COVID-19 and Myocardial Injury.
Elevations in troponin levels have been shown to predict mortality in patients with coronavirus disease 2019 (COVID-19). The role of inflammation in myocardial injury remains unclear. We sought to determine the association of elevated troponin with mortality in a large, ethnically diverse population of patients hospita...
Journal Article;Observational Study
Majure, David T;Gruberg, Luis;Saba, Shahryar G;Kvasnovsky, Charlotte;Hirsch, Jamie S;Jauhar, Rajiv
10.1016/j.amjcard.2020.09.060
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Usefulness of Elevated Troponin to Predict Death in Patients With COVID-19 and Myocardial Injury. [Abstract]: Elevations in troponin levels have been shown to predict mortality in patients with coronavirus disease 2019 (COVID-19). The role of inflammation in myocardial injury remains unclear. We sought to dete...
32,376,581
Nan Fang Yi Ke Da Xue Xue Bao
[An increased neutrophil/lymphocyte ratio is an early warning signal of severe COVID-19].
OBJECTIVE: To identify the biomarkers as early warning signals for severe COVID-19. METHODS: We retrospectively analyzed the clinical data of 63 patients with COVID- 19 from Hubei Provincial Hospital of Integrated Chinese and Western Medicine, including 32 moderate cases and 31 severe cases. The demographic data, under...
covid-19;neutrophil/lymphocyte ratio;warning signal
Journal Article
Xia, Xintian;Wen, Minyong;Zhan, Shaofeng;He, Jing;Chen, Weitao
10.12122/j.issn.1673-4254.2020.03.06
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [An increased neutrophil/lymphocyte ratio is an early warning signal of severe COVID-19]. [Abstract]: OBJECTIVE: To identify the biomarkers as early warning signals for severe COVID-19. METHODS: We retrospectively analyzed the clinical data of 63 patients with COVID- 19 from Hubei Provincial Hospital of Integr...
32,509,310
New Microbes New Infect
Severe acute respiratory syndrome coronavirus 2: virus mutations in specific European populations.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is being intensively studied, particularly its evolution, in the increasingly available sequences between countries/continents with classical phylogenetic tree representation. More recently, certain protein mutations have been correlated with specific functio...
amino acid replacements;g- s- and v-clades;co-evolved mutations;coronavirus disease 2019;european countries
Journal Article
Coppee, F;Lechien, J R;Decleves, A-E;Tafforeau, L;Saussez, S
10.1016/j.nmni.2020.100696
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Severe acute respiratory syndrome coronavirus 2: virus mutations in specific European populations. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is being intensively studied, particularly its evolution, in the increasingly available sequences between countries/continents with classic...
32,830,894
Clin Cardiol
Canakinumab to reduce deterioration of cardiac and respiratory function in SARS-CoV-2 associated myocardial injury with heightened inflammation (canakinumab in Covid-19 cardiac injury: The three C study).
BACKGROUND: In patients with Covid-19, myocardial injury and increased inflammation are associated with morbidity and mortality. We designed a proof-of-concept randomized controlled trial to evaluate whether treatment with canakinumab prevents progressive respiratory failure and worsening cardiac dysfunction in patient...
covid-19;sars-cov-2;canakinumab;myocardial injury
Clinical Trial Protocol;Journal Article
Sheng, Calvin C;Sahoo, Debasis;Dugar, Siddharth;Prada, Robier Aguillon;Wang, Tom Kai Ming;Abou Hassan, Ossama K;Brennan, Danielle;Culver, Daniel A;Rajendram, Prabalini;Duggal, Abhijit;Lincoff, A Michael;Nissen, Steven E;Menon, Venu;Cremer, Paul C
10.1002/clc.23451
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Canakinumab to reduce deterioration of cardiac and respiratory function in SARS-CoV-2 associated myocardial injury with heightened inflammation (canakinumab in Covid-19 cardiac injury: The three C study). [Abstract]: BACKGROUND: In patients with Covid-19, myocardial injury and increased inflammation are associ...
32,594,627
Dermatol Ther
Evaluation of the effects of COVID-19 pandemic on hair diseases through a web-based questionnaire.
AIM: Current quarantine conditions are a difficult process for individuals and can worsen the psychological state. Increased psychosocial stress can affect the course of many common "stress-sensitive" skin conditions. This study examined the possible effects of coronavirus disease 2019 (COVID-19) on hair and scalp dise...
covid-19;alopecia areata;hair diseases;seborrheic dermatitis;telogen effluvium
Journal Article;Observational Study
Turkmen, Dursun;Altunisik, Nihal;Sener, Serpil;Colak, Cemil
10.1111/dth.13923
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Evaluation of the effects of COVID-19 pandemic on hair diseases through a web-based questionnaire. [Abstract]: AIM: Current quarantine conditions are a difficult process for individuals and can worsen the psychological state. Increased psychosocial stress can affect the course of many common "stress-sensitive"...
32,691,014
Infect Dis Model
Bidirectional impact of imperfect mask use on reproduction number of COVID-19: A next generation matrix approach.
The use of masks as a means of reducing transmission of COVID-19 outside healthcare settings has proved controversial. Masks are thought to have two modes of effect: they prevent infection with COVID-19 in wearers; and prevent transmission by individuals with subclinical infection. We used a simple next-generation matr...
assortative;covid-19;epidemics;epidemiology;masks;mixing;next generation matrix;sars-cov-2
Journal Article
Fisman, David N;Greer, Amy L;Tuite, Ashleigh R
10.1016/j.idm.2020.06.004
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Bidirectional impact of imperfect mask use on reproduction number of COVID-19: A next generation matrix approach. [Abstract]: The use of masks as a means of reducing transmission of COVID-19 outside healthcare settings has proved controversial. Masks are thought to have two modes of effect: they prevent infect...
32,864,341
IDCases
Adenovirus and novel coronavirus (SARS-Cov2) coinfection: A case report.
SARS-Cov2 coinfection with other respiratory viruses is very rare. Adenovirus coinfection is even more unusual. We report the case of a patient with poorly controlled diabetes, and he was admitted to the emergency department because of severe COVID-19 infection. He had unfavorable prognostic factors such as moderate ox...
adenovirus infections;case report;coinfection;pneumonia;severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Case Reports
Motta, Juan Camilo;Gomez, Carmen Cecilia
10.1016/j.idcr.2020.e00936
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Adenovirus and novel coronavirus (SARS-Cov2) coinfection: A case report. [Abstract]: SARS-Cov2 coinfection with other respiratory viruses is very rare. Adenovirus coinfection is even more unusual. We report the case of a patient with poorly controlled diabetes, and he was admitted to the emergency department b...
32,534,186
Int J Antimicrob Agents
Procalcitonin levels in COVID-19 patients.
Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a pandemic. This study analysed 95 SARS-CoV-2-infected patients, including 62 moderate COVID-19 patients, 21 severe COVID-19 patients and 12 critical COVID-19 patients (6 patient...
covid-19;coronavirus;procalcitonin;prognosis;sars-cov-2;severity
Journal Article
Hu, Rui;Han, Chaofei;Pei, Shiyao;Yin, Mingzhu;Chen, Xiang
10.1016/j.ijantimicag.2020.106051
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Procalcitonin levels in COVID-19 patients. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a pandemic. This study analysed 95 SARS-CoV-2-infected patients, including 62 moderate COVID-19 patients, 21 sever...
32,278,147
Infect Genet Evol
Mathematical model of infection kinetics and its analysis for COVID-19, SARS and MERS.
The purpose of this paper is to reveal the spread rules of the three pneumonia: COVID-19, SARS and MERS. We compare the new spread characteristics of COVID-19 with those of SARS and MERS. By considering the growth rate and inhibition constant of infectious diseases, their propagation growth model is established. The pa...
2008 msc: r181.2;covid-19;coronavirus;infectious kinetics;mers;sars
Journal Article;Research Support, Non-U.S. Gov't
Liang, Kaihao
10.1016/j.meegid.2020.104306
[ 0, 0, 0, 0, 1, 1, 0 ]
[Title]: Mathematical model of infection kinetics and its analysis for COVID-19, SARS and MERS. [Abstract]: The purpose of this paper is to reveal the spread rules of the three pneumonia: COVID-19, SARS and MERS. We compare the new spread characteristics of COVID-19 with those of SARS and MERS. By considering the growt...
32,952,488
Vacunas
[Epidemic trends of COVID-19 in ten countries compared with Turkey].
INTRODUCTION: The outbreak rapidly spread to more than 200 countries and led to millions of confirmed cases as well as thousands of deaths worldwide. This makes a serious threat to the world in terms of public health. The present study aimed to compare the COVID-19 epidemic parameters in Turkey with the top ten countri...
covid-19;turkey;coronavirus;epidemiology
Journal Article
Durmus, Veli
10.1016/j.vacun.2020.08.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Epidemic trends of COVID-19 in ten countries compared with Turkey]. [Abstract]: INTRODUCTION: The outbreak rapidly spread to more than 200 countries and led to millions of confirmed cases as well as thousands of deaths worldwide. This makes a serious threat to the world in terms of public health. The present ...
32,522,666
Immunol Lett
How nicotine can inhibit cytokine storm in the lungs and prevent or lessen the severity of COVID-19 infection?
Statistical surveys of COVID-19 patients indicate, against all common logic, that people who smoke are less prone to the infection and/or exhibit less severe respiratory symptoms than non-smokers. This suggests that nicotine may have some preventive or modulatory effect on the inflammatory response in the lungs. Becaus...
acute respiratory distress syndrome - ards;covid-19;cytokine storm;cytokines;inflammation;lungs;macrophages;nicotine;sars-cov-2;alpha4/alpha7 nicotinic ach receptors - nachrs
Letter
Kloc, Malgorzata;Ghobrial, Rafik M;Kubiak, Jacek Z
10.1016/j.imlet.2020.06.002
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: How nicotine can inhibit cytokine storm in the lungs and prevent or lessen the severity of COVID-19 infection? [Abstract]: Statistical surveys of COVID-19 patients indicate, against all common logic, that people who smoke are less prone to the infection and/or exhibit less severe respiratory symptoms than non-...
32,711,898
J Natl Med Assoc
On Answering the Call to Action for COVID-19: Continuing a Bold Legacy of Health Advocacy.
The indelible impacts on our nation from the Coronavirus pandemic along with high fatality rates that disproportionately burden racial and ethnic minorities necessitate long-term coordinated federal, state and local action to improve critical determinants of population health, specifically important health and public h...
coronavirus pandemic;emergency and disaster preparedness;health and public health infrastructures;racial and ethnic health disparities;structural and social determinants of health
Journal Article
Morgan, Randall C Jr;Reid, Tiffany N
10.1016/j.jnma.2020.06.011
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: On Answering the Call to Action for COVID-19: Continuing a Bold Legacy of Health Advocacy. [Abstract]: The indelible impacts on our nation from the Coronavirus pandemic along with high fatality rates that disproportionately burden racial and ethnic minorities necessitate long-term coordinated federal, state an...
32,666,912
J Man Manip Ther
COVID 19 and manual therapy: international lessons and perspectives on current and future clinical practice and education.
BACKGROUND: The COVID-19 pandemic has altered clinical practice and education in manual therapy globally. Social distancing has limited in-person care and changed health-care provision. Education in manual therapy has moved to online platforms with in-person instruction restricted. The global impact on the clinical pra...
covid-19;clinical practice;education;manual therapy;pandemic
Journal Article
MacDonald, C W;Lonnemann, E;Petersen, S M;Rivett, Darren A;Osmotherly, P G;Brismee, J M
10.1080/10669817.2020.1782059
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID 19 and manual therapy: international lessons and perspectives on current and future clinical practice and education. [Abstract]: BACKGROUND: The COVID-19 pandemic has altered clinical practice and education in manual therapy globally. Social distancing has limited in-person care and changed health-care p...
33,005,518
Cureus
A Novel Case of Hypoparathyroidism Secondary to SARS-CoV-2 Infection.
Hypoparathyroidism is usually caused by postsurgical or autoimmune damage to the parathyroid gland. We present the case of a 46-year-old Hispanic male with no significant past medical history who was admitted to the hospital with hypoxic respiratory failure due to coronavirus disease 2019 (COVID-19) infection and had a...
hyperphosphatemia;hypoparathyroidism
Case Reports
Elkattawy, Sherif;Alyacoub, Ramez;Ayad, Sarah;Pandya, Manthan;Eckman, Ari
10.7759/cureus.10097
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Novel Case of Hypoparathyroidism Secondary to SARS-CoV-2 Infection. [Abstract]: Hypoparathyroidism is usually caused by postsurgical or autoimmune damage to the parathyroid gland. We present the case of a 46-year-old Hispanic male with no significant past medical history who was admitted to the hospital with...
32,662,084
J Surg Oncol
Bone sarcoma surgery in times of COVID-19 pandemic lockdown-early experience from a tertiary centre in India.
BACKGROUND AND OBJECTIVES: Coronavirus disease 2019 (COVID-19) lockdown has presented a unique challenge for sarcoma care. The purpose of this study is to evaluate the early results and feasibility of surgeries for bone sarcomas during the COVID-19 lockdown. METHODS: Our prospectively collected orthopaedic oncological ...
covid-19;bone tumour surgery;lockdown;orthopaedic oncology;safety;sarcoma treatment
Journal Article
Kumar, Venkatesan Sampath;Banjara, Roshan;Thapa, Sushma;Majeed, Abdul;Kapoor, Love;Janardhanan, Ritvik;Bakhshi, Sameer;Kumar, Vijay;Malhotra, Rajesh;Khan, Shah Alam
10.1002/jso.26112
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Bone sarcoma surgery in times of COVID-19 pandemic lockdown-early experience from a tertiary centre in India. [Abstract]: BACKGROUND AND OBJECTIVES: Coronavirus disease 2019 (COVID-19) lockdown has presented a unique challenge for sarcoma care. The purpose of this study is to evaluate the early results and fea...
32,917,746
Clin Med (Lond)
The clinical sensitivity of a single SARS-CoV-2 upper respiratory tract RT-PCR test for diagnosing COVID-19 using convalescent antibody as a comparator.
The clinical false negative rate of reverse transcriptase polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 on a single upper respiratory tract sample was calculated using convalescent antibody testing as a comparator. The sensitivity in symptomatic individuals was 86.2% (25/29). Of the missed cases, one (3.5%)...
covid-19;covid-19 antibody;sars-cov-2 rt-pcr;clinical sensitivity
Journal Article
Holborow, Abigail;Asad, Hibo;Porter, Lavinia;Tidswell, Poppy;Johnston, Claire;Blyth, Ian;Bone, Alice;Healy, Brendan
10.7861/clinmed.2020-0555
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The clinical sensitivity of a single SARS-CoV-2 upper respiratory tract RT-PCR test for diagnosing COVID-19 using convalescent antibody as a comparator. [Abstract]: The clinical false negative rate of reverse transcriptase polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 on a single upper respiratory ...
32,879,697
J Grad Med Educ
From Medical School to Residency: Transitions During the COVID-19 Pandemic.
Background: The start of a new academic year in graduate medical education will mark a transition for postgraduate year 1 (PGY-1) residents from medical school into residency. The relocation of individuals has significant implications given the COVID-19 pandemic and variability of the outbreak across the United States,...
News
Byrne, Lauren M;Holmboe, Eric S;Combes, John R;Nasca, Thomas J
10.4300/JGME-D-20-00627.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: From Medical School to Residency: Transitions During the COVID-19 Pandemic. [Abstract]: Background: The start of a new academic year in graduate medical education will mark a transition for postgraduate year 1 (PGY-1) residents from medical school into residency. The relocation of individuals has significant i...
32,397,558
J Clin Med
Impact of COVID-19 on the Cardiovascular System: A Review.
The recent outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has been declared a public health emergency of international concern. COVID-19 may present as acute respiratory distress syndrome in severe cases, and patients with pre-existing cardiovascular comorbidit...
covid-19;cardiovascular disease;myocardial injury
Journal Article;Review
Matsushita, Kensuke;Marchandot, Benjamin;Jesel, Laurence;Ohlmann, Patrick;Morel, Olivier
10.3390/jcm9051407
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on the Cardiovascular System: A Review. [Abstract]: The recent outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has been declared a public health emergency of international concern. COVID-19 may present as acute respiratory distress sy...
32,685,170
Basic Clin Androl
COVID-19 and andrology: Recommendations of the French-speaking society of andrology (Societe d'Andrologie de langue Francaise SALF).
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) metamorphosed our medical practice. In early June 2020, more than 6,400,000 COVID-19 (coronavirus-19 disease) cases were diagnosed across the world and more than 380,000 deaths were linked to COVID-19. Many medical symptoms of COVID-19 were reported. We will ...
andrological care;assisted reproductive technologies;covid-19;fever;male;orchitis;sars-cov-2;semen;testis;testosterone
Journal Article
Hamdi, S;Bendayan, M;Huyghe, E;Soufir, J-C;Amar, E;El Osta, R;Plotton, I;Delalande, C;Perrin, J;Leroy, C;Bouker, A;Pons, H;Lejeune, H;Robin, G;Boitrelle, F
10.1186/s12610-020-00106-4
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and andrology: Recommendations of the French-speaking society of andrology (Societe d'Andrologie de langue Francaise SALF). [Abstract]: SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) metamorphosed our medical practice. In early June 2020, more than 6,400,000 COVID-19 (coronavirus-19 dise...
32,886,678
PLoS Negl Trop Dis
Knowledge, attitudes, practices of/towards COVID 19 preventive measures and symptoms: A cross-sectional study during the exponential rise of the outbreak in Cameroon.
Severe Acute Respiratory Syndrome Coronavirus 2 (COVID 19) has plagued the world with about 7,8 million confirmed cases and over 430,000 deaths as of June 13th, 2020. The knowledge, attitude, and practices (KAP) people hold towards this new disease could play a major role in the way they accept measures put in place to...
Journal Article
Ngwewondo, Adela;Nkengazong, Lucia;Ambe, Lum Abienwi;Ebogo, Jean Thierry;Mba, Fabrice Medou;Goni, Hamadama Oumarou;Nyunai, Nyemb;Ngonde, Marie Chantal;Oyono, Jean-Louis Essame
10.1371/journal.pntd.0008700
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge, attitudes, practices of/towards COVID 19 preventive measures and symptoms: A cross-sectional study during the exponential rise of the outbreak in Cameroon. [Abstract]: Severe Acute Respiratory Syndrome Coronavirus 2 (COVID 19) has plagued the world with about 7,8 million confirmed cases and over 430...
32,504,360
World J Pediatr
SARS-CoV-2 infection in infants under 1 year of age in Wuhan City, China.
BACKGROUND: The clinical characteristics and outcome of COVID-19 in children are different from those in adults. We aimed to describe the characteristics of infants under 1 year of age (excluding newborns) with COVID-19. METHODS: We retrospectively retrieved data of 36 infants with SARS-CoV-2 infection in Wuhan Childre...
covid-19;coronavirus infant infection;sars-cov-2
Journal Article
Sun, Dan;Chen, Xue;Li, Hui;Lu, Xiao-Xia;Xiao, Han;Zhang, Fu-Rong;Liu, Zhi-Sheng
10.1007/s12519-020-00368-y
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection in infants under 1 year of age in Wuhan City, China. [Abstract]: BACKGROUND: The clinical characteristics and outcome of COVID-19 in children are different from those in adults. We aimed to describe the characteristics of infants under 1 year of age (excluding newborns) with COVID-19. METH...
32,755,198
AJR Am J Roentgenol
Lung Ultrasound Findings in Patients With Coronavirus Disease (COVID-19).
OBJECTIVE. Although chest CT is the standard imaging modality in early diagnosis and management of coronavirus disease (COVID-19), the use of lung ultrasound (US) presents some advantages over the use of chest CT and may play a complementary role in the workup of COVID-19. The objective of our study was to investigate ...
covid-19;us;coronavirus disease;sonography;ultrasound
Journal Article
Zhang, Yao;Xue, Heng;Wang, Mixue;He, Nan;Lv, Zhibin;Cui, Ligang
10.2214/AJR.20.23513
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung Ultrasound Findings in Patients With Coronavirus Disease (COVID-19). [Abstract]: OBJECTIVE. Although chest CT is the standard imaging modality in early diagnosis and management of coronavirus disease (COVID-19), the use of lung ultrasound (US) presents some advantages over the use of chest CT and may play...
32,936,770
J Med Internet Res
Identification of Risk Factors and Symptoms of COVID-19: Analysis of Biomedical Literature and Social Media Data.
BACKGROUND: In December 2019, the COVID-19 outbreak started in China and rapidly spread around the world. Lack of a vaccine or optimized intervention raised the importance of characterizing risk factors and symptoms for the early identification and successful treatment of patients with COVID-19. OBJECTIVE: This study a...
covid-19;sars-cov-2;twitter;biomedical literature;diagnosis;risk factor;social media;symptom;treatment;tweets
Journal Article;Meta-Analysis
Jeon, Jouhyun;Baruah, Gaurav;Sarabadani, Sarah;Palanica, Adam
10.2196/20509
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Identification of Risk Factors and Symptoms of COVID-19: Analysis of Biomedical Literature and Social Media Data. [Abstract]: BACKGROUND: In December 2019, the COVID-19 outbreak started in China and rapidly spread around the world. Lack of a vaccine or optimized intervention raised the importance of characteri...
32,496,723
Pediatr Emerg Med Pract
COVID-19: The impact on pediatric emergency care
Although there is still much that is not understood, experience with previous coronavirus outbreaks and available data on COVID-19 indicate a reduced propensity to affect children. Nonetheless, serious complications-although rare-are being seen in pediatric patients. This review, written with the emergency medicine cli...
Journal Article;Review
Walker, David M;Tolentino, Victorio R
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: The impact on pediatric emergency care [Abstract]: Although there is still much that is not understood, experience with previous coronavirus outbreaks and available data on COVID-19 indicate a reduced propensity to affect children. Nonetheless, serious complications-although rare-are being seen in pe...
32,297,796
Circulation
Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome.
Coronavirus disease 2019 (COVID-19) is a rapidly expanding global pandemic caused by severe acute respiratory syndrome coronavirus 2, resulting in significant morbidity and mortality. A substantial minority of patients hospitalized develop an acute COVID-19 cardiovascular syndrome, which can manifest with a variety of ...
covid-19;sars-cov-2;cardiomyopathies;heart failure;myocarditis
Journal Article;Review
Hendren, Nicholas S;Drazner, Mark H;Bozkurt, Biykem;Cooper, Leslie T Jr
10.1161/CIRCULATIONAHA.120.047349
[ 1, 1, 1, 1, 0, 0, 0 ]
[Title]: Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome. [Abstract]: Coronavirus disease 2019 (COVID-19) is a rapidly expanding global pandemic caused by severe acute respiratory syndrome coronavirus 2, resulting in significant morbidity and mortality. A substantial minority of patien...
32,595,355
Turk J Biol
Virtual drug repurposing study against SARS-CoV-2 TMPRSS2 target.
Currently, the world suffers from a new coronavirus SARS-CoV-2 that causes COVID-19. Therefore, there is a need for the urgent development of novel drugs and vaccines for COVID-19. Since it can take years to develop new drugs against this disease, here we used a hybrid combined molecular modeling approach in virtual dr...
covid19;drug repurposing;sars-cov-2;tmprss2
Journal Article
DurdaGi, Serdar
10.3906/biy-2005-112
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Virtual drug repurposing study against SARS-CoV-2 TMPRSS2 target. [Abstract]: Currently, the world suffers from a new coronavirus SARS-CoV-2 that causes COVID-19. Therefore, there is a need for the urgent development of novel drugs and vaccines for COVID-19. Since it can take years to develop new drugs against...
32,865,152
J Prim Care Community Health
A Retrospective Analysis and Comparison of Prisoners and Community-Based Patients with COVID-19 Requiring Intensive Care During the First Phase of the Pandemic in West Texas.
BACKGROUND: COVID-19 is a highly infectious disease which usually presents with respiratory symptoms. This virus is disseminated through respiratory droplets, and, therefore, individuals residing in close quarters are at a higher risk for the acquisition of infection. The prison population is at a significantly increas...
covid-19;west texas;hospitalization;intensive care;outcomes;prisoners
Comparative Study;Journal Article
Ali, Kiran;Rao, Sanjana;Berdine, Gilbert;Test, Victor;Nugent, Kenneth
10.1177/2150132720954687
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Retrospective Analysis and Comparison of Prisoners and Community-Based Patients with COVID-19 Requiring Intensive Care During the First Phase of the Pandemic in West Texas. [Abstract]: BACKGROUND: COVID-19 is a highly infectious disease which usually presents with respiratory symptoms. This virus is dissemin...
32,402,186
ACS Comb Sci
Targeting the Dimerization of the Main Protease of Coronaviruses: A Potential Broad-Spectrum Therapeutic Strategy.
A new coronavirus (CoV) caused a pandemic named COVID-19, which has become a global health care emergency in the present time. The virus is referred to as SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) and has a genome similar ( approximately 82%) to that of the previously known SARS-CoV (SARS coronavirus...
3clpro;covid-19;sars-cov;sars-cov-2;broad-spectrum antiviral agents;coronavirus;dimerization;homodimer;main protease (mpro);mutation
Journal Article;Review
Goyal, Bhupesh;Goyal, Deepti
10.1021/acscombsci.0c00058
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Targeting the Dimerization of the Main Protease of Coronaviruses: A Potential Broad-Spectrum Therapeutic Strategy. [Abstract]: A new coronavirus (CoV) caused a pandemic named COVID-19, which has become a global health care emergency in the present time. The virus is referred to as SARS-CoV-2 (severe acute resp...
32,839,665
Food Secur
10 recommendations for African governments to ensure food security for poor and vulnerable populations during COVID-19.
In addressing COVID-19, African governments should not forget the livelihoods as well as the food and nutrition security of their citizens. With over 70% of the workforce in the informal sector without any social protection and health insurance, the pandemic could have a devastating impact on income and livelihoods as ...
coronavirus;food security;nutrition;sub-saharan africa
Journal Article
Lawson-Lartego, Late;Cohen, Marc J
10.1007/s12571-020-01062-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: 10 recommendations for African governments to ensure food security for poor and vulnerable populations during COVID-19. [Abstract]: In addressing COVID-19, African governments should not forget the livelihoods as well as the food and nutrition security of their citizens. With over 70% of the workforce in the i...
32,836,520
Braz J Anesthesiol
Recommendations for Cardiopulmonary Resuscitation (CPR) of patients with suspected or confirmed COVID-19.
The care for patients suffering from cardiopulmonary arrest in a context of a COVID-19 pandemic has particularities that should be highlighted. The following recommendations from the Brazilian Association of Emergency Medicine (ABRAMEDE), the Brazilian Society of Cardiology (SBC) and the Brazilian Association of Intens...
advanced cardiac life support;arrest, cardiopulmonary;cardiopulmonary resuscitation;heart arrest
Journal Article;Review
Timerman, Sergio;Guimaraes, Helio Penna;Rodrigues, Roseny Dos Reis;Correa, Thiago Domingos;Schubert, Daniel Ujakow Correa;Freitas, Ana Paula;Neto, Alvaro Rea;Polastri, Thatiane Facholi;Vane, Matheus Fachini;Couto, Thomaz Bittencourt;Brandao, Antonio Carlos Aguiar;Giannetti, Natali Schiavo;Carmona, Maria Jose Carvalho;T...
10.1016/j.bjane.2020.06.007
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for Cardiopulmonary Resuscitation (CPR) of patients with suspected or confirmed COVID-19. [Abstract]: The care for patients suffering from cardiopulmonary arrest in a context of a COVID-19 pandemic has particularities that should be highlighted. The following recommendations from the Brazilian ...
33,001,967
PLoS Med
Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study.
BACKGROUND: Loss of smell and taste are commonly reported symptoms associated with coronavirus disease 2019 (COVID-19); however, the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in people with acute loss of smell and/or taste is unknown. The study aimed to determine the sero...
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Makaronidis, Janine;Mok, Jessica;Balogun, Nyaladzi;Magee, Cormac G;Omar, Rumana Z;Carnemolla, Alisia;Batterham, Rachel L
10.1371/journal.pmed.1003358
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study. [Abstract]: BACKGROUND: Loss of smell and taste are commonly reported symptoms associated with coronavirus disease 2019 (COVID-...
32,801,803
Infect Drug Resist
The Coronavirus Disease 2019 (COVID-19) in Children: A Study in an Iranian Children's Referral Hospital.
Background: Despite the worldwide spread of the coronavirus disease 2019 (COVID-19), the epidemiological and clinical patterns of the COVID-19 infection remain largely unclear, particularly among children. In this study, we explored the epidemiological characteristics, clinical patterns, and laboratory and imaging find...
covid-19;iran;children;severe pneumonia
Journal Article
Mahmoudi, Shima;Mehdizadeh, Mehrzad;Shervin Badv, Reza;Navaeian, Amene;Pourakbari, Babak;Rostamyan, Maryam;Sharifzadeh Ekbatani, Meisam;Eshaghi, Hamid;Abdolsalehi, Mohammad Reza;Alimadadi, Hosein;Movahedi, Zahra;Mamishi, Setareh
10.2147/IDR.S259064
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Coronavirus Disease 2019 (COVID-19) in Children: A Study in an Iranian Children's Referral Hospital. [Abstract]: Background: Despite the worldwide spread of the coronavirus disease 2019 (COVID-19), the epidemiological and clinical patterns of the COVID-19 infection remain largely unclear, particularly amon...
32,951,933
J Emerg Med
Emergency Department Management of the Sexual Assault Victim in the COVID Era: A Model SAFET-I Guideline From San Diego County.
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has contributed to an increase in intimate partner violence (IPV), posing challenges to health care providers who must protect themselves and others during sexual assault examinations. Victims of sexual assault encountered in prehospital and emergency departm...
covid-19;coronavirus;domestic violence;forensics;intimate partner violence;sexual assault;sexual assault examination;sexual assault guidelines;trauma-informed care
Journal Article
Koenig, Kristi L;Benjamin, Stephanie B;Bey, Christian K;Dickinson, Sue;Shores, Michelle
10.1016/j.jemermed.2020.07.047
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency Department Management of the Sexual Assault Victim in the COVID Era: A Model SAFET-I Guideline From San Diego County. [Abstract]: BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has contributed to an increase in intimate partner violence (IPV), posing challenges to health care providers ...
33,068,757
Clin Microbiol Infect
Specificity and positive predictive value of SARS-CoV-2 nucleic acid amplification testing in a low-prevalence setting.
OBJECTIVES: When the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is low, many positive test results are false positives. Confirmatory testing reduces overdiagnosis and nosocomial infection and enables real-world estimates of test specificity and positive predictive value. This study estim...
covid-19 diagnostic testing;covid-19 pandemic;nucleic acid amplification techniques;sars-cov-2;sensitivity and specificity
Journal Article
Skittrall, Jordan P;Wilson, Michael;Smielewska, Anna A;Parmar, Surendra;Fortune, Mary D;Sparkes, Dominic;Curran, Martin D;Zhang, Hongyi;Jalal, Hamid
10.1016/j.cmi.2020.10.003
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Specificity and positive predictive value of SARS-CoV-2 nucleic acid amplification testing in a low-prevalence setting. [Abstract]: OBJECTIVES: When the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is low, many positive test results are false positives. Confirmatory testing reduce...
32,845,301
J Gerontol A Biol Sci Med Sci
Clinical Characteristics and Outcomes of 821 Older Patients With SARS-Cov-2 Infection Admitted to Acute Care Geriatric Wards.
BACKGROUND: There is limited information describing the characteristics and outcomes of hospitalized older patients with confirmed coronavirus disease 2019 (COVID-19). METHOD: We conducted a multicentric retrospective cohort study in 13 acute COVID-19 geriatric wards, from March 13 to April 15, 2020, in Paris area. All...
covid-19;geriatrics;in-hospital mortality
Journal Article
Zerah, Lorene;Baudouin, Edouard;Pepin, Marion;Mary, Morgane;Krypciak, Sebastien;Bianco, Celine;Roux, Swasti;Gross, Ariane;Tomeo, Charlotte;Lemarie, Nadege;Dureau, Antoine;Bastiani, Sophie;Ketz, Flora;Boully, Clemence;de Villelongue, Cedric;Romdhani, Mouna;Desoutter, Marie-Astrid;Duron, Emmanuelle;David, Jean-Philippe;T...
10.1093/gerona/glaa210
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics and Outcomes of 821 Older Patients With SARS-Cov-2 Infection Admitted to Acute Care Geriatric Wards. [Abstract]: BACKGROUND: There is limited information describing the characteristics and outcomes of hospitalized older patients with confirmed coronavirus disease 2019 (COVID-19). METHO...
32,868,967
Chaos Solitons Fractals
A Bayesian approach for monitoring epidemics in presence of undetected cases.
One of the key indicators used in tracking the evolution of an infectious disease is the reproduction number. This quantity is usually computed using the reported number of cases, but ignoring that many more individuals may be infected (e.g. asymptomatic carriers). We develop a Bayesian procedure to quantify the impact...
bayesian inference;covid-19;computational epidemiology;stochastic process
Journal Article
De Simone, Andrea;Piangerelli, Marco
10.1016/j.chaos.2020.110167
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: A Bayesian approach for monitoring epidemics in presence of undetected cases. [Abstract]: One of the key indicators used in tracking the evolution of an infectious disease is the reproduction number. This quantity is usually computed using the reported number of cases, but ignoring that many more individuals m...
32,880,277
S Afr Med J
The effect of COVID-19 on essential surgical admissions in South Africa: A retrospective observational analysis of admissions before and during lockdown at a tertiary healthcare complex.
BACKGROUND: With COVID-19 having spread across the globe, it has become standard to implement infection control strategies (colloquially known as lockdown) with the intention of reducing the magnitude and delaying the peak of the epidemiological curve. Personal infection mitigation strategies coupled with lockdown have...
Journal Article;Observational Study
Moustakis, J;Piperidis, A A;Ogunrombi, A B
10.7196/SAMJ.2020.v110i9.15025
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The effect of COVID-19 on essential surgical admissions in South Africa: A retrospective observational analysis of admissions before and during lockdown at a tertiary healthcare complex. [Abstract]: BACKGROUND: With COVID-19 having spread across the globe, it has become standard to implement infection control ...
32,434,963
J Contemp Dent Pract
2019 Novel Coronavirus Outbreak: SOS Alert for Dentists.
On January 31, 2020, novel coronavirus (nCoV), a zoonotic virus yet to be identified into the taxonomy, created a powerful ripple through mankind that the World Health Organization has declared a global health emergency.(1) This is definitely not the first time that an alarm has been rung by this family of viruses. Epi...
Journal Article
Vidya, G S;Patil, Shankargouda;Raj, A Thirumal
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: 2019 Novel Coronavirus Outbreak: SOS Alert for Dentists. [Abstract]: On January 31, 2020, novel coronavirus (nCoV), a zoonotic virus yet to be identified into the taxonomy, created a powerful ripple through mankind that the World Health Organization has declared a global health emergency.(1) This is definitely...
33,039,714
EBioMedicine
A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19.
BACKGROUND: Prognostic tools are required to guide clinical decision-making in COVID-19. METHODS: We studied the relationship between the ratio of interleukin (IL)-6 to IL-10 and clinical outcome in 80 patients hospitalized for COVID-19, and created a simple 5-point linear score predictor of clinical outcome, the Dubli...
covid-19;clinical outcome;cytokines;inflammation;interleukin-10;interleukin-6;prognostic score
Journal Article
McElvaney, Oliver J;Hobbs, Brian D;Qiao, Dandi;McElvaney, Oisin F;Moll, Matthew;McEvoy, Natalie L;Clarke, Jennifer;O'Connor, Eoin;Walsh, Sean;Cho, Michael H;Curley, Gerard F;McElvaney, Noel G
10.1016/j.ebiom.2020.103026
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19. [Abstract]: BACKGROUND: Prognostic tools are required to guide clinical decision-making in COVID-19. METHODS: We studied the relationship between the ratio of interleukin (IL)-6 to IL-10 and clinical ...
32,886,893
Acta Clin Belg
The influence of COVID-19 on routine hematological parameters of hospitalized patients.
OBJECTIVES: Coronavirus disease 2019 (COVID-19) was first discovered in Wuhan, China, in December 2019, and soon spread around the entire world. As no effective treatment is known, prediction of disease severity is very important in order to estimate a patients outcome. Aim of this study was to evaluate routine hematol...
covid-19;sars-cov-2;coronavirus disease;hematology parameters;lymphocyte count
Journal Article
Blomme, S;Smets, L;Van Ranst, M;Boeckx, N;Van Laer, C
10.1080/17843286.2020.1814649
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The influence of COVID-19 on routine hematological parameters of hospitalized patients. [Abstract]: OBJECTIVES: Coronavirus disease 2019 (COVID-19) was first discovered in Wuhan, China, in December 2019, and soon spread around the entire world. As no effective treatment is known, prediction of disease severity...
32,317,220
J Autoimmun
The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19.
The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has posed the world at a pandemic risk. Coronavirus-19 disease (COVID-19) is an infectious disease caused by SARS-CoV-2, which causes pneumonia, requires intensive care unit hospitalization in about 10% of cases and can lead to a...
autoimmunity;biologics;covid-19;coronavirus;dmards;il-6;immunosuppressant. il-1;infection;rheumatic;sars-cov-2;tdmards
Journal Article;Review
Perricone, Carlo;Triggianese, Paola;Bartoloni, Elena;Cafaro, Giacomo;Bonifacio, Angelo F;Bursi, Roberto;Perricone, Roberto;Gerli, Roberto
10.1016/j.jaut.2020.102468
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19. [Abstract]: The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has posed the world at a pandemic risk. Coronavirus-19 disease (COVID-19) is an infectious disease caused by SARS-CoV-2, which causes pneum...
32,226,285
Int J Biol Sci
SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat.
An ongoing outbreak of pneumonia caused by a novel coronavirus, currently designated as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was reported recently. However, as SARS-CoV-2 is an emerging virus, we know little about it. In this review, we summarize the key events occurred during the early sta...
covid-19;coronavirus;novel coronavirus;sars-cov-2;pneumonia
Journal Article;Research Support, Non-U.S. Gov't;Review
Zheng, Jun
10.7150/ijbs.45053
[ 1, 1, 0, 1, 1, 0, 0 ]
[Title]: SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat. [Abstract]: An ongoing outbreak of pneumonia caused by a novel coronavirus, currently designated as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was reported recently. However, as SARS-CoV-2 is an emerging virus, we know litt...
32,798,445
Cell Host Microbe
Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of human infections, and an effective vaccine is critical to mitigate coronavirus-induced disease 2019 (COVID-19). Previously, we developed a replication-competent vesicular stomatitis virus (VSV) expressing a modified form of the SARS-CoV...
covid-19;sars-cov-2;correlates;humoral immunity;immunity;neutralizing antibodies;vaccine;vesicular stomatitis virus
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Case, James Brett;Rothlauf, Paul W;Chen, Rita E;Kafai, Natasha M;Fox, Julie M;Smith, Brittany K;Shrihari, Swathi;McCune, Broc T;Harvey, Ian B;Keeler, Shamus P;Bloyet, Louis-Marie;Zhao, Haiyan;Ma, Meisheng;Adams, Lucas J;Winkler, Emma S;Holtzman, Michael J;Fremont, Daved H;Whelan, Sean P J;Diamond, Michael S
10.1016/j.chom.2020.07.018
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of human infections, and an effective vaccine is critical to mitigate coronavirus-induced disea...
32,720,698
J Rehabil Med
Rehabilitative of COVID-19 patients with acute lower extremity Ischemia and amputation.
OBJECTIVE: To evaluate the clinical characteristics and rehabilitation management of patients who undergo amputation for COVID-19-associated coagulopathy. METHODS: Clinical and laboratory data for 3 patients were analysed and their rehabilitative management discussed. RESULTS: The medical records of 3 patients who had ...
covid-19;covid-19 coagulopathy;sars-cov-2;amputation;ischaemia;rehabilitation
Case Reports;Journal Article
Brugliera, Luigia;Spina, Alfio;Castellazzi, Paola;Cimino, Paolo;Arcuri, Pietro;Deriu, Maria Grazia;Zanetta, Chiara;Angelone, Sara Monica;Capitanio, Jody Filippo;Alemanno, Federica;Meloni, Carlo;D'Angelo, Giuseppe;Houdayer, Elise;Abutalebi, Jubin;Mortini, Pietro;Iannaccone, Sandro
10.2340/16501977-2714
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Rehabilitative of COVID-19 patients with acute lower extremity Ischemia and amputation. [Abstract]: OBJECTIVE: To evaluate the clinical characteristics and rehabilitation management of patients who undergo amputation for COVID-19-associated coagulopathy. METHODS: Clinical and laboratory data for 3 patients wer...
32,467,443
Crit Care Med
Coagulopathy of Coronavirus Disease 2019.
OBJECTIVES: Recent studies have reported a high prevalence of thrombotic events in coronavirus disease 2019. However, the significance of thromboembolic complications has not been widely appreciated. The purpose of this review is to provide current knowledge of this serious problem. DESIGN: Narrative review. DATA SOURC...
Journal Article;Review
Iba, Toshiaki;Levy, Jerrold H;Levi, Marcel;Connors, Jean Marie;Thachil, Jecko
10.1097/CCM.0000000000004458
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coagulopathy of Coronavirus Disease 2019. [Abstract]: OBJECTIVES: Recent studies have reported a high prevalence of thrombotic events in coronavirus disease 2019. However, the significance of thromboembolic complications has not been widely appreciated. The purpose of this review is to provide current knowledg...
33,080,002
JAMA Intern Med
Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.
Importance: Therapies that improve survival in critically ill patients with coronavirus disease 2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 receptor, may counteract the inflammatory cytokine release syndrome in patients with severe COVID-19 illness. Objective: To test whethe...
Journal Article;Research Support, N.I.H., Extramural
Gupta, Shruti;Wang, Wei;Hayek, Salim S;Chan, Lili;Mathews, Kusum S;Melamed, Michal L;Brenner, Samantha K;Leonberg-Yoo, Amanda;Schenck, Edward J;Radbel, Jared;Reiser, Jochen;Bansal, Anip;Srivastava, Anand;Zhou, Yan;Finkel, Diana;Green, Adam;Mallappallil, Mary;Faugno, Anthony J;Zhang, Jingjing;Velez, Juan Carlos Q;Shaefi...
10.1001/jamainternmed.2020.6252
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19. [Abstract]: Importance: Therapies that improve survival in critically ill patients with coronavirus disease 2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 re...
32,678,542
Zh Nevrol Psikhiatr Im S S Korsakova
[Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care].
Novel coronavirus SARS-CoV-2 and COVID-19, besides affecting the respiratory system, may lead to central and peripheral nervous system disorders and also cause muscular symptoms. The authors review the literature and own clinical case with respect to nervous system involvement in COVID-19 patients. There is a correlati...
covid-19;guillen-barre syndrome;sars-cov-2;acute necrotizing encephalopathy;coronaviruses;multiple sclerosis;muscular system;nervous system;stroke
Journal Article;Review
Gusev, E I;Martynov, M Yu;Boyko, A N;Voznyuk, I A;Latsh, N Yu;Sivertseva, S A;Spirin, N N;Shamalov, N A
10.17116/jnevro20201200617
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: [Novel coronavirus infection (COVID-19) and nervous system involvement: pathogenesis, clinical manifestations, organization of neurological care]. [Abstract]: Novel coronavirus SARS-CoV-2 and COVID-19, besides affecting the respiratory system, may lead to central and peripheral nervous system disorders and als...
32,838,103
Hepatol Commun
Liver Transplantation in the Time of COVID19: Barriers and Ethical considerations for Management and Next Steps.
The recent outbreak of the novel virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) which causes COVID19 disease has spread globally affecting millions of people. This pandemic has taxed our healthcare system and disrupted normal operations, even of lifesaving procedures like liver transplants. During t...
Journal Article;Review
Jaffe, Ariel;Schilsky, Michael L;Deshpande, Ranjit;Batra, Ramesh
10.1002/hep4.1568
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Liver Transplantation in the Time of COVID19: Barriers and Ethical considerations for Management and Next Steps. [Abstract]: The recent outbreak of the novel virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) which causes COVID19 disease has spread globally affecting millions of people. This pa...
32,973,590
Front Psychiatry
COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review.
Background: In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvemen...
corona virus disease 2019;cognitive;neurological;neurotropic;scoping review
Journal Article;Review
Wenting, Angela;Gruters, Angelique;van Os, Yindee;Verstraeten, Sonja;Valentijn, Susanne;Ponds, Rudolf;de Vugt, Marjolein
10.3389/fpsyt.2020.00860
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review. [Abstract]: Background: In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summa...
32,445,105
Neurocrit Care
Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale.
BACKGROUND: As the COVID-19 pandemic developed, reports of neurological dysfunctions spanning the central and peripheral nervous systems have emerged. The spectrum of acute neurological dysfunctions may implicate direct viral invasion, para-infectious complications, neurological manifestations of systemic diseases, or ...
covid-19;coronavirus;neurological manifestations;neurological symptoms;sars-cov-2
Journal Article;Research Support, N.I.H., Extramural
Frontera, Jennifer;Mainali, Shraddha;Fink, Ericka L;Robertson, Courtney L;Schober, Michelle;Ziai, Wendy;Menon, David;Kochanek, Patrick M;Suarez, Jose I;Helbok, Raimund;McNett, Molly;Chou, Sherry H-Y
10.1007/s12028-020-00995-3
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale. [Abstract]: BACKGROUND: As the COVID-19 pandemic developed, reports of neurological dysfunctions spanning the central and peripheral nervous systems have emerged. The spectrum of acute neurological dys...
32,552,595
J Biomol Struct Dyn
Natural compounds from Clerodendrum spp. as possible therapeutic candidates against SARS-CoV-2: An in silico investigation.
The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has rattled global public health, with researchers struggling to find specific therapeutic solutions. In this context, the present study employed an in silico approach to assess the inhibitory potential of the phytochemicals obtained from GC-MS analysis o...
clerodendrum spp;mm-gbsa;sars-cov-2;drug-likeness;molecular docking;molecular dynamics simulations;taraxerol
Journal Article
Kar, Pallab;Sharma, Neeta Raj;Singh, Bhupender;Sen, Arnab;Roy, Ayan
10.1080/07391102.2020.1780947
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Natural compounds from Clerodendrum spp. as possible therapeutic candidates against SARS-CoV-2: An in silico investigation. [Abstract]: The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has rattled global public health, with researchers struggling to find specific therapeutic solutions. In this ...
32,439,646
AJNR Am J Neuroradiol
Hemorrhagic Posterior Reversible Encephalopathy Syndrome as a Manifestation of COVID-19 Infection.
We describe 2 hospitalized patients with confirmed coronavirus 19 (COVID-19) infection in whom brain imaging showed hemorrhagic posterior reversible encephalopathy syndrome, and we discuss the possible reasons for these findings and their relationship to the infection.
Case Reports;Journal Article
Franceschi, A M;Ahmed, O;Giliberto, L;Castillo, M
10.3174/ajnr.A6595
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Hemorrhagic Posterior Reversible Encephalopathy Syndrome as a Manifestation of COVID-19 Infection. [Abstract]: We describe 2 hospitalized patients with confirmed coronavirus 19 (COVID-19) infection in whom brain imaging showed hemorrhagic posterior reversible encephalopathy syndrome, and we discuss the possibl...
32,271,861
Ann Intern Med
Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey.
BACKGROUND: The evolving outbreak of coronavirus disease 2019 (COVID-19) is requiring social distancing and other measures to protect public health. However, messaging has been inconsistent and unclear. OBJECTIVE: To determine COVID-19 awareness, knowledge, attitudes, and related behaviors among U.S. adults who are mor...
Journal Article;Multicenter Study;Research Support, N.I.H., Extramural
Wolf, Michael S;Serper, Marina;Opsasnick, Lauren;O'Conor, Rachel M;Curtis, Laura;Benavente, Julia Yoshino;Wismer, Guisselle;Batio, Stephanie;Eifler, Morgan;Zheng, Pauline;Russell, Andrea;Arvanitis, Marina;Ladner, Daniela;Kwasny, Mary;Persell, Stephen D;Rowe, Theresa;Linder, Jeffrey A;Bailey, Stacy C
10.7326/M20-1239
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey. [Abstract]: BACKGROUND: The evolving outbreak of coronavirus disease 2019 (COVID-19) is requiring social distancing and other measures to protect public health...
32,985,709
J Card Surg
COVID-19: A perspective from Iran.
The coronavirus disease 2019 (COVID-19) pandemic has presented unique challenges to healthcare systems the world over. The management of the current pandemic places a huge strain on healthcare sectors and demands new strategies on a global level. We herein review the latest epidemiologic data on the COVID-19 pandemic, ...
covid-19;iran;cardiac surgery impact;coronavirus
Journal Article;Review
Ahmadi, Zargham H;Mousavizadeh, Mostafa;Nikpajouh, Akbar;Bahsir, Mohamad;Hosseini, Saeid
10.1111/jocs.15054
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: A perspective from Iran. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has presented unique challenges to healthcare systems the world over. The management of the current pandemic places a huge strain on healthcare sectors and demands new strategies on a global level. We herein review ...
32,418,556
Disaster Med Public Health Prep
Predicted Effects of Stopping COVID-19 Lockdown on Italian Hospital Demand.
OBJECTIVES: Italy has been one of the first countries to implement mitigation measures to curb the coronavirus disease 2019 (COVID-19) pandemic. There is currently a debate on when and how such measures should be loosened. To forecast the demand for hospital intensive care unit (ICU) and non-ICU beds for COVID-19 patie...
covid-19;intensive care;pandemic;surge capacity
Journal Article
Bollon, Jordy;Paganini, Matteo;Nava, Consuelo Rubina;De Vita, Nello;Vaschetto, Rosanna;Ragazzoni, Luca;Della Corte, Francesco;Barone-Adesi, Francesco
10.1017/dmp.2020.157
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Predicted Effects of Stopping COVID-19 Lockdown on Italian Hospital Demand. [Abstract]: OBJECTIVES: Italy has been one of the first countries to implement mitigation measures to curb the coronavirus disease 2019 (COVID-19) pandemic. There is currently a debate on when and how such measures should be loosened. ...
32,491,178
J Infect Dis
The Issue of Recurrently Positive Patients Who Recovered From COVID-19 According to the Current Discharge Criteria: Investigation of Patients from Multiple Medical Institutions in Wuhan, China.
The current discharge criteria for COVID-19 require that patients have 2 consecutive negative results for reverse transcription polymerase chain reaction (RT-PCR) detection. Here, we observed that recurrent positive RT-PCR test results in patients with 3 consecutive negative results (5.4%) were significantly decreased ...
covid-19 pneumonia;rt-pcr detection;sars-cov-2 virus;recurrently positive
Journal Article;Research Support, Non-U.S. Gov't
Zou, You;Wang, Bin-Ru;Sun, Liu;Xu, Shan;Kong, Yong-Gang;Shen, Li-Jun;Liang, Geng-Tian;Chen, Shi-Ming
10.1093/infdis/jiaa301
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Issue of Recurrently Positive Patients Who Recovered From COVID-19 According to the Current Discharge Criteria: Investigation of Patients from Multiple Medical Institutions in Wuhan, China. [Abstract]: The current discharge criteria for COVID-19 require that patients have 2 consecutive negative results for...
32,210,741
EXCLI J
Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target.
Direct-acting antivirals are effective tools to control viral infections. SARS-CoV-2 is a coronavirus associated with the epidemiological outbreak in late 2019. Previous reports showed that HIV-1 protease inhibitors could block SARS-CoV main protease. Based on that and using an in silico approach, we evaluated SARS-CoV...
coronavirus;hiv;sars-cov-2;protease;treatment
Journal Article
Ortega, Joseph Thomas;Serrano, Maria Luisa;Pujol, Flor Helene;Rangel, Hector Rafael
10.17179/excli2020-1189
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target. [Abstract]: Direct-acting antivirals are effective tools to control viral infections. SARS-CoV-2 is a coronavirus associated with the epidemiological outbreak in late 2019. Previ...
32,319,956
JMIR Public Health Surveill
Surveillance of COVID-19 in the General Population Using an Online Questionnaire: Report From 18,161 Respondents in China.
BACKGROUND: The recent outbreak of the coronavirus disease (COVID-19) has become an international pandemic. So far, little is known about the role of an internet approach in COVID-19 participatory surveillance. OBJECTIVE: The aim of this study is to investigate whether an online survey can provide population-level info...
covid-19;wuhan;coronavirus;online questionnaire;participatory surveillance;surveillance;syndromic surveillance
Journal Article;Research Support, Non-U.S. Gov't
Luo, Hongxing;Lie, Yongchan;Prinzen, Frits W
10.2196/18576
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surveillance of COVID-19 in the General Population Using an Online Questionnaire: Report From 18,161 Respondents in China. [Abstract]: BACKGROUND: The recent outbreak of the coronavirus disease (COVID-19) has become an international pandemic. So far, little is known about the role of an internet approach in CO...
32,636,755
Front Pharmacol
Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19.
Tocilizumab has been proposed as a means of opposing hyperinflammatory responses in intensive care patients with COVID-19. Here, we briefly discuss the potentially multiple, synergistic mechanisms whereby tocilizumab might exert therapeutic activity, mostly focusing on the production of tryptophan-derived catabolites t...
covid-19;ido1;cytokine storm syndrome;tocilizumab;tryptophan catabolism
Journal Article;Review
Belladonna, Maria Laura;Orabona, Ciriana
10.3389/fphar.2020.00959
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19. [Abstract]: Tocilizumab has been proposed as a means of opposing hyperinflammatory responses in intensive care patients with COVID-19. Here, we briefly discuss the potentially multiple, synergistic mechanisms whereby tocili...
32,539,282
A A Pract
Use of Anesthesia Machines in a Critical Care Setting During the Coronavirus Disease 2019 Pandemic.
The coronavirus disease 2019 (COVID-19) pandemic created an unprecedented need for mechanical ventilation in critically ill patients. To meet this increased demand, some facilities were forced to use anesthesia gas machines (AGMs) as intensive care unit (ICU) ventilators. While an off-label use, AGM manufacturers, the ...
Journal Article
Haina, Kent M K Jr
10.1213/XAA.0000000000001243
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Use of Anesthesia Machines in a Critical Care Setting During the Coronavirus Disease 2019 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic created an unprecedented need for mechanical ventilation in critically ill patients. To meet this increased demand, some facilities were forced to use...
32,340,021
Blood Purif
Early Leukapheresis Depletion in an Ex-Premature with Severe Acute Respiratory Distress Syndrome Due to Bordetella Pertussis and Coronavirus Infection.
We describe a 2 weeks corrected gestational age infant admitted in pediatric intensive care unit (PICU) for severe acute respiratory distress syndrome (ARDS) associated to Bordetella pertussis and Coronavirus infection. He developed leukocytosis as soon as ARDS required intubation and aggressive mechanical ventilation:...
acute respiratory distress syndrome;bordetella pertussis;hyperleukocytosis;infant;intensive care;leukapheresis;pediatric;pulmonary hypertension
Case Reports
Rossetti, Emanuele;Appierto, Linda;Meschini, Antonella;Leone, Giovanna;Lazzaro, Stefania;Del Principe, Giovanna;Bianchi, Roberto;Picardo, Sergio
10.1159/000507873
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Early Leukapheresis Depletion in an Ex-Premature with Severe Acute Respiratory Distress Syndrome Due to Bordetella Pertussis and Coronavirus Infection. [Abstract]: We describe a 2 weeks corrected gestational age infant admitted in pediatric intensive care unit (PICU) for severe acute respiratory distress syndr...
33,004,164
Best Pract Res Clin Anaesthesiol
Impact of COVID-19 pandemic on chronic pain management: Looking for the best way to deliver care.
Although pain treatment has been described as a fundamental human right, the Coronavirus disease 2019 (COVID-19) pandemic forced healthcare systems worldwide to redistribute healthcare resources toward intensive care units and other COVID-19 dedicated sites. As most chronic pain services were subsequently deemed non-ur...
covid-19;chronic pain;interventional pain;telemedicine
Journal Article;Review
Puntillo, Filomena;Giglio, Mariateresa;Brienza, Nicola;Viswanath, Omar;Urits, Ivan;Kaye, Alan D;Pergolizzi, Joseph;Paladini, Antonella;Varrassi, Giustino
10.1016/j.bpa.2020.07.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 pandemic on chronic pain management: Looking for the best way to deliver care. [Abstract]: Although pain treatment has been described as a fundamental human right, the Coronavirus disease 2019 (COVID-19) pandemic forced healthcare systems worldwide to redistribute healthcare resources toward...
32,377,932
J Mol Evol
Animal-to-Human Viral Transitions: Is SARS-CoV-2 an Evolutionarily Successful One?
Transmission of viruses from one species to another is not unusual in nature. Despite this, evolutionarily successful transmissions are rare. Such events can cause pandemics and are followed by host-virus coevolution procedures that can increase the fitness potential of viruses. In this perspective article, I recognize...
covid-19;epidemic;gene;infection;molecular evolution;mutation;natural selection
Letter
Voskarides, Konstantinos
10.1007/s00239-020-09947-z
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Animal-to-Human Viral Transitions: Is SARS-CoV-2 an Evolutionarily Successful One? [Abstract]: Transmission of viruses from one species to another is not unusual in nature. Despite this, evolutionarily successful transmissions are rare. Such events can cause pandemics and are followed by host-virus coevolution...
32,878,977
Genome Res
Mapping genome variation of SARS-CoV-2 worldwide highlights the impact of COVID-19 super-spreaders.
The human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the major pandemic of the twenty-first century. We analyzed more than 4700 SARS-CoV-2 genomes and associated metadata retrieved from public repositories. SARS-CoV-2 sequences have a high sequence identity (>99.9%), which ...
Journal Article;Research Support, Non-U.S. Gov't
Gomez-Carballa, Alberto;Bello, Xabier;Pardo-Seco, Jacobo;Martinon-Torres, Federico;Salas, Antonio
10.1101/gr.266221.120
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Mapping genome variation of SARS-CoV-2 worldwide highlights the impact of COVID-19 super-spreaders. [Abstract]: The human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the major pandemic of the twenty-first century. We analyzed more than 4700 SARS-CoV-2 genomes and as...
32,899,333
Diagnostics (Basel)
Sensitivity, Specificity and Predictive Values of Molecular and Serological Tests for COVID-19: A Longitudinal Study in Emergency Room.
BACKGROUND: We assessed the sensitivity, specificity and positive and negative predictive value (PPV and NPV) of molecular and serological tests for the diagnosis of SARS-CoV-2 infection. METHODS: A total of 346 patients were enrolled in the emergency room. We evaluated three Reverse Transcriptase-real time PCRs (RT-PC...
rt-pcr;sars-cov-2;accuracy;diagnosis;serology
Journal Article
Bisoffi, Zeno;Pomari, Elena;Deiana, Michela;Piubelli, Chiara;Ronzoni, Niccolo;Beltrame, Anna;Bertoli, Giulia;Riccardi, Niccolo;Perandin, Francesca;Formenti, Fabio;Gobbi, Federico;Buonfrate, Dora;Silva, Ronaldo
10.3390/diagnostics10090669
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Sensitivity, Specificity and Predictive Values of Molecular and Serological Tests for COVID-19: A Longitudinal Study in Emergency Room. [Abstract]: BACKGROUND: We assessed the sensitivity, specificity and positive and negative predictive value (PPV and NPV) of molecular and serological tests for the diagnosis ...
32,760,579
F1000Res
Impact of COVID-19 on the access to hearing health care services for children with cochlear implants: a survey of parents.
Background: The COVID-19 pandemic has affected the world in an unprecedented manner. It has aggravated psychological distress in parents of children with cochlear implants. Continuous use of a speech sound processor is critical for auditory stimulation in children with cochlear implants. However, movement restrictions ...
cochlear implants;hearing health services;parental reactions;pediatric hearing loss
Journal Article
Ayas, Mohammed;Ali Al Amadi, Ahmad Mohd Haider;Khaled, Duaa;Alwaa, Ahmad Munzer
10.12688/f1000research.24915.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on the access to hearing health care services for children with cochlear implants: a survey of parents. [Abstract]: Background: The COVID-19 pandemic has affected the world in an unprecedented manner. It has aggravated psychological distress in parents of children with cochlear implants. Con...
32,992,323
Obes Facts
A Time Frame for Testing Negative for SARS-COV2 in People with Obesity.
OBJECTIVE: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. METHODS: We followed 34 patients with laboratory-confirmed COVID-19 in...
obesity;overweight;sars-cov2
Journal Article
Dicker, Dror;Lev, Shaul;Gottesman, Tamar;Kournos, Tatiana;Dotan, Maya;Ashorov, Nina;Marcoviciu, Dana;Golan, Rachel
10.1159/000511738
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A Time Frame for Testing Negative for SARS-COV2 in People with Obesity. [Abstract]: OBJECTIVE: Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of...
32,920,452
Diagn Microbiol Infect Dis
COVID-19: Is there a role for Western blots and skin testing for determining immunity and development of a vaccine?
Infection with the virus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) stimulates an immune response which can serve as a marker for current or past exposure to this pathogen, and possibly for resistance to re-infection. This response to COVID-19 can be monitored based on the production of antibodies, a...
covid-19;delayed-type hypersensitivity;sars-cov-2;serology;vaccine development;western blots
Editorial
Pavia, Charles S;Wormser, Gary P
10.1016/j.diagmicrobio.2020.115148
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Is there a role for Western blots and skin testing for determining immunity and development of a vaccine? [Abstract]: Infection with the virus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) stimulates an immune response which can serve as a marker for current or past exposure to this p...