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32,765,270
Front Pharmacol
The Folate Concentration and/or Folic Acid Metabolites in Plasma as Factor for COVID-19 Infection.
Pregnant women appear to be more susceptible to infectious diseases than women in reproductive age. According to the California Department of Public Health pregnant women were 9.6-folds more likely to be hospitalized during the 2009 influenza outbreak when compared to non-pregnant women in reproductive age. In contrast...
sars-cov-2;ace2;folic acid;furin;viral infection
Journal Article
Acosta-Elias, Jesus;Espinosa-Tanguma, Ricardo
10.3389/fphar.2020.01062
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Folate Concentration and/or Folic Acid Metabolites in Plasma as Factor for COVID-19 Infection. [Abstract]: Pregnant women appear to be more susceptible to infectious diseases than women in reproductive age. According to the California Department of Public Health pregnant women were 9.6-folds more likely to...
32,467,007
Transfus Apher Sci
Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19) using convalescent plasma.
BACKGROUND: Because treatment options for coronavirus disease 2019 (COVID-19) are very limited, the use of convalescent plasma has bee explored. CASE PRESENTATION AND TREATMENT: A male centenarian with cough and dyspnea for 2 months was diagnosed with COVID-19. Without effective treatments and with the increased risks ...
coronavirus disease 2019;convalescent plasma;transfusion
Case Reports;Journal Article
Kong, Yujie;Cai, Chen;Ling, Li;Zeng, Li;Wu, Meihong;Wu, Yanyun;Zhang, Wei;Liu, Zhong
10.1016/j.transci.2020.102820
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19) using convalescent plasma. [Abstract]: BACKGROUND: Because treatment options for coronavirus disease 2019 (COVID-19) are very limited, the use of convalescent plasma has bee explored. CASE PRESENTATION AND TREATMENT: A male centenar...
32,775,377
World J Clin Cases
Clinical characteristics of patients with COVID-19 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series.
BACKGROUND: A large number of pneumonia cases due to coronavirus disease 2019 (COVID-19) have been first reported in China. Meanwhile, the virus is sweeping all around the world and has infected millions of people. Fever and pulmonary symptoms have been noticed as major and early signs of infection, whereas gastrointes...
covid-19;gastrointestinal symptoms;hospitalization;initial symptoms;viral transmission
Journal Article
Yang, Tuo-Yun;Li, Yuan-Chao;Wang, Si-Cong;Dai, Qing-Qing;Jiang, Xue-Song;Zuo, Shu;Jia, Liu;Zheng, Jun-Bo;Wang, Hong-Liang
10.12998/wjcc.v8.i14.2950
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics of patients with COVID-19 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series. [Abstract]: BACKGROUND: A large number of pneumonia cases due to coronavirus disease 2019 (COVID-19) have been first reported in China. Meanwhile, the virus is sweeping a...
32,833,773
Crit Care Nurs Q
Supportive Management and Interventions for Respiratory Failure Due to SARS-CoV-2.
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can vary from asymptomatic to severe symptoms. It can lead to respiratory failure and acute respiratory distress syndrome requiring intubation and mechanical ventilation. Triaging patients is key to prevent spread, conserving medical resources, and ...
Journal Article;Review
Baltaji, Stephanie;Ledgerwood, Chelsea;Finoli, Lauren;Lyons, Caitlin;Cheema, Tariq
10.1097/CNQ.0000000000000322
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Supportive Management and Interventions for Respiratory Failure Due to SARS-CoV-2. [Abstract]: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can vary from asymptomatic to severe symptoms. It can lead to respiratory failure and acute respiratory distress syndrome requiring intubation an...
32,708,449
Healthcare (Basel)
Advance Care Planning (ACP) vs. Advance Serious Illness Preparations and Planning (ASIPP).
COVID-19 has highlighted the reality of an impending serious illness for many, particularly for older persons. Those faced with severe COVID-19 infection or other serious illness will be faced with decisions regarding admission to intensive care and use of mechanical ventilation. Past research has documented substantia...
advance care planning;communication and decision-making;critical care;end of life;serious illness
Journal Article
Heyland, Daren K
10.3390/healthcare8030218
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Advance Care Planning (ACP) vs. Advance Serious Illness Preparations and Planning (ASIPP). [Abstract]: COVID-19 has highlighted the reality of an impending serious illness for many, particularly for older persons. Those faced with severe COVID-19 infection or other serious illness will be faced with decisions ...
32,657,272
Soc Sci Med
Changes in population movement make COVID-19 spread differently from SARS.
This comment discusses the contribution of population movement to the spread of COVID-19, with a reference to the spread of SARS 17 years ago. We argue that the changing geography of migration, the diversification of jobs taken by migrants, the rapid growth of tourism and business trips, and the longer distance taken b...
covid-19;china;population movement;sars;spread
Journal Article;Research Support, Non-U.S. Gov't
Shi, Qiujie;Dorling, Danny;Cao, Guangzhong;Liu, Tao
10.1016/j.socscimed.2020.113036
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Changes in population movement make COVID-19 spread differently from SARS. [Abstract]: This comment discusses the contribution of population movement to the spread of COVID-19, with a reference to the spread of SARS 17 years ago. We argue that the changing geography of migration, the diversification of jobs ta...
32,901,940
J Cell Physiol
ACE2: Its potential role and regulation in severe acute respiratory syndrome and COVID-19.
COVID-19, a new disease caused by the 2019-novel coronavirus (SARS-CoV-2), has swept the world and challenged its culture, economy, and health infrastructure. Forced emergence to find an effective vaccine to immunize people has led scientists to design and examine vaccine candidates all over the world. Until a vaccine ...
ace2;ards;covid-19;sars-cov-2;angiotensin-converting enzyme 2;mirna
Journal Article;Review
Rezaei, Mitrasadat;Ziai, Seyed Ali;Fakhri, Sajad;Pouriran, Ramin
10.1002/jcp.30041
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: ACE2: Its potential role and regulation in severe acute respiratory syndrome and COVID-19. [Abstract]: COVID-19, a new disease caused by the 2019-novel coronavirus (SARS-CoV-2), has swept the world and challenged its culture, economy, and health infrastructure. Forced emergence to find an effective vaccine to ...
33,014,283
J Radiat Oncol
Early detection of SARS-CoV-2 from staging PET-CT.
Objective: SARS-CoV-2 infection may manifest with minimal or no clinical symptoms. However, signs of infection may appear on routine imaging obtained in the care of patients with cancer. The management of patients planned for chemoradiation with asymptomatic or mildly symptomatic SARS-CoV-2 infection is uncertain. Meth...
anal cancer;covid-19;cancer staging;chemoradiation;coronavirus
Journal Article;Review
Khattab, Mohamed H;Sherry, Alexander D;Jessop, Aaron C;Ciombor, Kristen K;Chakravarthy, Bapsi
10.1007/s13566-020-00436-w
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Early detection of SARS-CoV-2 from staging PET-CT. [Abstract]: Objective: SARS-CoV-2 infection may manifest with minimal or no clinical symptoms. However, signs of infection may appear on routine imaging obtained in the care of patients with cancer. The management of patients planned for chemoradiation with as...
32,682,192
Am J Otolaryngol
Subjective smell and taste changes during the COVID-19 pandemic: Short term recovery.
Since the COVID-19 pandemic began, many individuals have reported acute loss of smell and taste. In order to better characterize all patients with these symptoms, a longitudinal national survey was created. Since April 10, 2020, 549 completed the initial survey, with 295 completing 14-day, and 202 completing 1-month fo...
covid-19;coronavirus;epidemiology;recovery;smell;taste
Journal Article
Reiter, Evan R;Coelho, Daniel H;Kons, Zachary A;Costanzo, Richard M
10.1016/j.amjoto.2020.102639
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Subjective smell and taste changes during the COVID-19 pandemic: Short term recovery. [Abstract]: Since the COVID-19 pandemic began, many individuals have reported acute loss of smell and taste. In order to better characterize all patients with these symptoms, a longitudinal national survey was created. Since ...
32,999,356
Sci Rep
Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy.
SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Here, we investigated the interaction of this new coronavirus with Vero cells using high resolution scanning electron microscopy. Surface morphology, the interior of infected cells and the distribution of viral particles in both environments were observed 2 and ...
Journal Article;Research Support, Non-U.S. Gov't
Caldas, Lucio Ayres;Carneiro, Fabiana Avila;Higa, Luiza Mendonca;Monteiro, Fabio Luiz;da Silva, Gustavo Peixoto;da Costa, Luciana Jesus;Durigon, Edison Luiz;Tanuri, Amilcar;de Souza, Wanderley
10.1038/s41598-020-73162-5
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy. [Abstract]: SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Here, we investigated the interaction of this new coronavirus with Vero cells using high resolution scanning electron mi...
32,395,423
Med Mycol Case Rep
Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report.
It is not yet known, if critically ill COVID-19 patients are prone to fungal infections. We report a 69-year-old patient without typical risk factors for invasive pulmonary aspergillosis (IPA), who developed IPA two weeks after onset of symptoms. Our report shows that IPA may occur in critically ill COVID-19 patients.
aspergillosis;covid-19;icu
Case Reports
Prattes, Juergen;Valentin, Thomas;Hoenigl, Martin;Talakic, Emina;Reisinger, Alexander C;Eller, Philipp
10.1016/j.mmcr.2020.05.001
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report. [Abstract]: It is not yet known, if critically ill COVID-19 patients are prone to fungal infections. We report a 69-year-old patient without typical risk factors for invasive pulmonary aspergillosis (IPA), who developed IPA two ...
32,947,171
Respir Med
Pulmonary artery thrombi are co-located with opacifications in SARS-CoV2 induced ARDS.
PURPOSE: Patients hospitalized for infection with SARS-CoV-2 typically present with pneumonia. The respiratory failure is frequently complicated by pulmonary embolism in segmental pulmonary arteries. The distribution of pulmonary embolism in regard to lung parenchymal opacifications has not been investigated yet. METHO...
covid19;ct-scan;ctpa;pulmonary artery thrombosis;pulmonary embolism;sars-cov2
Journal Article;Research Support, Non-U.S. Gov't
Mueller-Peltzer, Katharina;Krauss, Tobias;Benndorf, Matthias;Lang, Corinna N;Bamberg, Fabian;Bode, Christoph;Duerschmied, Daniel;Staudacher, Dawid L;Zotzmann, Viviane
10.1016/j.rmed.2020.106135
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Pulmonary artery thrombi are co-located with opacifications in SARS-CoV2 induced ARDS. [Abstract]: PURPOSE: Patients hospitalized for infection with SARS-CoV-2 typically present with pneumonia. The respiratory failure is frequently complicated by pulmonary embolism in segmental pulmonary arteries. The distribu...
32,575,825
Int J Environ Res Public Health
Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality.
This study aims to underline the clinical characteristics of patients who died after testing positive for SARS-CoV-2 infection in one region of Italian and to evaluate the influence of underlying health conditions on the fatal outcome. A matched case-control study was designed by analyzing the data regarding positive s...
covid-19;italy;sars-cov-2;lethality;underlying health conditions
Journal Article
Deiana, Giovanna;Azara, Antonio;Dettori, Marco;Delogu, Fiorenzo;Vargiu, Gavino;Gessa, Isabella;Stroscio, Filippo;Tidore, Marcello;Steri, Giorgio;Castiglia, Paolo
10.3390/ijerph17124450
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality. [Abstract]: This study aims to underline the clinical characteristics of patients who died after testing positive for SARS-CoV-2 infection in one region of Italian and to evaluate the influence of under...
32,604,462
Biochem Mol Biol Educ
Virtual laboratory lessons in enzymology.
The recent COVID-19 pandemic has led to widespread lock-down strategies that force universities to perform all educational activities remotely. In this context, laboratory lessons pose a significant challenge. Here, I present an on-line tool that simulates the kinetics of chemical reactions. Enzymatic mechanisms can be...
computers in research and teaching;enzymes and catalysis;laboratory exercises
Journal Article;Research Support, Non-U.S. Gov't
Quesada, Victor
10.1002/bmb.21394
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Virtual laboratory lessons in enzymology. [Abstract]: The recent COVID-19 pandemic has led to widespread lock-down strategies that force universities to perform all educational activities remotely. In this context, laboratory lessons pose a significant challenge. Here, I present an on-line tool that simulates ...
32,401,680
Stroke
Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic.
The coronavirus disease 2019 (COVID-19) pandemic has broad implications on stroke patient triage. Emergency medical services providers have to ensure timely transfer of patients while minimizing the risk of infectious exposure for themselves, their co-workers, and other patients. This statement paper provides a concept...
covid-19;emergencies;pandemics;stroke;triage
Journal Article
Goyal, Mayank;Ospel, Johanna M;Southerland, Andrew M;Wira, Charles;Amin-Hanjani, Sepideh;Fraser, Justin F;Panagos, Peter
10.1161/STROKEAHA.120.030340
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has broad implications on stroke patient triage. Emergency medical services providers have to ensure timely transfer of patients while minimizing the risk of infectious exposur...
32,519,035
Virchows Arch
Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital.
With the continuous spreading of SARS-CoV-2 and increasing number of deaths worldwide, the need and appropriateness for autopsy in patients with COVID-19 became a matter of discussion. In fact, in the COVID-19 era protection of healthcare workers is a priority besides patient management. No evidence is currently availa...
autopsy;biosafety;covid-19;hazard group;infectious disease protocols
Journal Article
Basso, Cristina;Calabrese, Fiorella;Sbaraglia, Marta;Del Vecchio, Claudia;Carretta, Giovanni;Saieva, Annamaria;Donato, Daniele;Flor, Luciano;Crisanti, Andrea;Dei Tos, Angelo Paolo
10.1007/s00428-020-02861-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital. [Abstract]: With the continuous spreading of SARS-CoV-2 and increasing number of deaths worldwide, the need and appropriateness for autopsy in patients with COVID-19 became a matter o...
32,287,083
Acad Med
Five Questions for Residency Leadership in the Time of COVID-19: Reflections of Chief Medical Residents From an Internal Medicine Program.
The COVID-19 pandemic has drastically affected the traditional methods residency programs use to train their residents. Chief residents serve a unique role as part of the residency leadership to foster the education and development of the residents. Given the rapid shift in demands on physicians in the face of the pand...
Journal Article
Rakowsky, Shana;Flashner, Bess M;Doolin, Jim;Reese, Zachary;Shpilsky, Jason;Yang, Shu;Smith, C Christopher;Graham, Kelly
10.1097/ACM.0000000000003419
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Five Questions for Residency Leadership in the Time of COVID-19: Reflections of Chief Medical Residents From an Internal Medicine Program. [Abstract]: The COVID-19 pandemic has drastically affected the traditional methods residency programs use to train their residents. Chief residents serve a unique role as p...
32,509,415
AJP Rep
Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19.
Our understanding of COVID-19 in pregnant and postpartum women is rapidly evolving. We present a case from March 2020 of a 25-year-old G2P2002 whose delivery was complicated by preeclampsia with severe features who presented to the emergency department 9 days after cesarean delivery with chest tightness and dyspnea on ...
covid-19;heart failure with preserved ejection fraction;hypertensive emergency;preeclampsia
Case Reports
Sinkey, Rachel G;Rajapreyar, Indranee;Robbins, Lindsay S;Dionne-Odom, Jodie;Pogwizd, Steven M;Casey, Brian M;Tita, Alan T N
10.1055/s-0040-1712926
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19. [Abstract]: Our understanding of COVID-19 in pregnant and postpartum women is rapidly evolving. We present a case from March 2020 of a 25-year-old G2P2002 whose delivery was complicated by preecl...
32,385,052
Sci Immunol
HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19.
JAK kinase inhibitors are being investigated as a way of managing cytokine storm in severe COVID-19 patients.
Journal Article
Spinelli, Francesca Romana;Conti, Fabrizio;Gadina, Massimo
10.1126/sciimmunol.abc5367
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19. [Abstract]: JAK kinase inhibitors are being investigated as a way of managing cytokine storm in severe COVID-19 patients. [Keywords]:
33,065,291
Acad Pediatr
Rapid-cycle community assessment of health-related social needs of children and families during COVID-19.
OBJECTIVE: To identify unmet health and social resource needs during a county-wide COVID-19 stay-at-home order and phased re-opening in Western Pennsylvania. METHODS: With public health, social service, and community partners connected through an ongoing academic-community collaborative, we developed and fielded a week...
covid-19;children;coronavirus;health-related social needs
Journal Article
Ray, Kristin N;Ettinger, Anna K;Dwarakanath, Namita;Mistry, Sejal V;Bey, Jamil;Chaves-Gnecco, Diego;Alston, Kaila A;Ripper, Lisa;Lavage, Daniel R;Landsittel, Douglas P;Miller, Elizabeth
10.1016/j.acap.2020.10.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rapid-cycle community assessment of health-related social needs of children and families during COVID-19. [Abstract]: OBJECTIVE: To identify unmet health and social resource needs during a county-wide COVID-19 stay-at-home order and phased re-opening in Western Pennsylvania. METHODS: With public health, social...
32,436,005
Urolithiasis
How does the COVID-19 pandemic affect the preoperative evaluation and anesthesia applied for urinary stones? EULIS eCORE-IAU multicenter collaborative cohort study.
Stone disease is a unique condition that requires appropriate management in a timely manner as it can result in both emergent conditions and long term effects on kidney functions. In this study it is aimed to identify the up-to-date practice patterns related to preoperative evaluation and anesthesia for stone disease i...
anesthesia;covid-19;kidney stones;nephrolithiasis;pandemic;sars-cov-2;urolithiasis
Journal Article;Multicenter Study
Gokce, Mehmet Ilker;Yin, Shanfeng;Sonmez, Mehmet Giray;Eryildirim, Bilal;Kallidonis, Panagiotis;Petkova, Kremena;Guven, Selcuk;Kiremit, Murat Can;de Lorenzis, Elisa;Tefik, Tzevat;Villa, Luca;Zeng, Guohua;Sarica, Kemal
10.1007/s00240-020-01193-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: How does the COVID-19 pandemic affect the preoperative evaluation and anesthesia applied for urinary stones? EULIS eCORE-IAU multicenter collaborative cohort study. [Abstract]: Stone disease is a unique condition that requires appropriate management in a timely manner as it can result in both emergent conditio...
32,614,817
PLoS Comput Biol
Estimation of country-level basic reproductive ratios for novel Coronavirus (SARS-CoV-2/COVID-19) using synthetic contact matrices.
The 2019-2020 pandemic of atypical pneumonia (COVID-19) caused by the virus SARS-CoV-2 has spread globally and has the potential to infect large numbers of people in every country. Estimating the country-specific basic reproductive ratio is a vital first step in public-health planning. The basic reproductive ratio (R0)...
Journal Article;Research Support, Non-U.S. Gov't
Hilton, Joe;Keeling, Matt J
10.1371/journal.pcbi.1008031
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Estimation of country-level basic reproductive ratios for novel Coronavirus (SARS-CoV-2/COVID-19) using synthetic contact matrices. [Abstract]: The 2019-2020 pandemic of atypical pneumonia (COVID-19) caused by the virus SARS-CoV-2 has spread globally and has the potential to infect large numbers of people in e...
32,769,038
Cancer Treat Rev
Metronomic chemotherapy for patients with metastatic breast cancer: Review of effectiveness and potential use during pandemics.
Metronomic chemotherapy (M-CT) is defined as dose dense administration of chemotherapy at lower doses than maximum tolerated dose but at shorter free intervals, to obtain a near continuous exposure of cancer cells to those potentially effective drugs. M-CT is a useful strategy to obtain response, overcome resistance an...
anti-angiogenic effect;covid-19;cytostatic effect;cytotoxic effect;metastatic breast cancer;metronomic chemotherapy;t- regulatory cells
Journal Article;Review
Fares, Johny E;El Tomb, Paul;Khalil, Lana E;Atwani, Rula W;Moukadem, Hiba A;Awada, Ahmad;El Saghir, Nagi S
10.1016/j.ctrv.2020.102066
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Metronomic chemotherapy for patients with metastatic breast cancer: Review of effectiveness and potential use during pandemics. [Abstract]: Metronomic chemotherapy (M-CT) is defined as dose dense administration of chemotherapy at lower doses than maximum tolerated dose but at shorter free intervals, to obtain ...
33,047,100
Am J Obstet Gynecol MFM
Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population.
Background: Older age and medical comorbidities are identified risk factors for developing severe coronavirus disease 2019. However, there are limited data on risk stratification, clinical and laboratory course, and optimal management of coronavirus disease 2019 in pregnancy. Objective: Our study aimed to describe the ...
hispanic ethnicity;coronavirus;coronavirus disease 2019;pregnancy;severe acute respiratory syndrome coronavirus 2
Journal Article
Grechukhina, Olga;Greenberg, Victoria;Lundsberg, Lisbet S;Deshmukh, Uma;Cate, Jennifer;Lipkind, Heather S;Campbell, Katherine H;Pettker, Christian M;Kohari, Katherine S;Reddy, Uma M
10.1016/j.ajogmf.2020.100246
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population. [Abstract]: Background: Older age and medical comorbidities are identified risk factors for developing severe coronavirus disease 2019. However, there are limited data on risk stratification, clinical and laboratory co...
32,925,789
Medicine (Baltimore)
Plum-blossom needle for coronavirus disease 2019-related headache: A protocol for systematic review and meta-analysis.
BACKGROUND: Assessing the effectiveness and safety of plum-blossom needle for (COVID-19) related headache is the main purpose of this systematic review protocol. METHODS: We will search the following sources for the identification of trials: The Cochrane Library, PubMed, EMBASE, Chinese Biomedical Literature Database (...
Journal Article
Gao, Wei;Li, Jingfei;Huang, Guoxiang
10.1097/MD.0000000000022179
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Plum-blossom needle for coronavirus disease 2019-related headache: A protocol for systematic review and meta-analysis. [Abstract]: BACKGROUND: Assessing the effectiveness and safety of plum-blossom needle for (COVID-19) related headache is the main purpose of this systematic review protocol. METHODS: We will s...
32,842,655
Int J Environ Res Public Health
Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators.
In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are often stretched beyond capacity. There are widespread reports of dwindling supplies of personal protective equipment (PPE), particularly N95-type filtering facepiece respirators (FFRs), which are paramount to protect frontline medical/nursing staff, and to mi...
covid-19;n95;sars-cov-1;sars-cov-2;uvc;coronavirus;decontamination;disinfection;filtering facepiece respirators;heat;personal protective equipment;reuse;temperature;ultraviolet light;viability
Journal Article;Review
Derraik, Jose G B;Anderson, William A;Connelly, Elizabeth A;Anderson, Yvonne C
10.3390/ijerph17176117
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators. [Abstract]: In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are often stretched beyond capacity. There are widespread reports of dwindl...
32,402,088
Age Ageing
Commentary: COVID in care homes-challenges and dilemmas in healthcare delivery.
The COVID-19 pandemic has disproportionately affected care home residents internationally, with 19-72% of COVID-19 deaths occurring in care homes. COVID-19 presents atypically in care home residents and up to 56% of residents may test positive whilst pre-symptomatic. In this article, we provide a commentary on challeng...
covid-19; nursing homes; older people; pandemic
Journal Article
Gordon, Adam L;Goodman, Claire;Achterberg, Wilco;Barker, Robert O;Burns, Eileen;Hanratty, Barbara;Martin, Finbarr C;Meyer, Julienne;O'Neill, Desmond;Schols, Jos;Spilsbury, Karen
10.1093/ageing/afaa113
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Commentary: COVID in care homes-challenges and dilemmas in healthcare delivery. [Abstract]: The COVID-19 pandemic has disproportionately affected care home residents internationally, with 19-72% of COVID-19 deaths occurring in care homes. COVID-19 presents atypically in care home residents and up to 56% of res...
32,536,978
Eur Cardiol
Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?
Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible mechanisms of myocardial injury in COVID-19 include ischaemia due to circulatory and respiratory failure, epicardial or intramyocardial s...
covid-19;sars-cov-2;cardiomyopathy;heart failure;myocardial injury;myocarditis;troponin
Journal Article;Review
Komiyama, Maki;Hasegawa, Koji;Matsumori, Akira
10.15420/ecr.2020.17
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early? [Abstract]: Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible me...
32,621,628
Dermatol Ther
Treatment concerns for bullous pemphigoid in the COVID-19 pandemic era.
Bullous pemphigoid (BP) is the most common autoimmune blistering disease with subepidermal involvement, typically affecting the elderly. It has spontaneous remissions and exacerbations with significant morbidity. A novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for ...
covid-19;dermatologic therapy;autoimmune bullous disease
Journal Article;Review
Azimi, Seyyede Zeinab;Firooz, Alireza;Murrell, Dedee F;Daneshpazhooh, Maryam
10.1111/dth.13956
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Treatment concerns for bullous pemphigoid in the COVID-19 pandemic era. [Abstract]: Bullous pemphigoid (BP) is the most common autoimmune blistering disease with subepidermal involvement, typically affecting the elderly. It has spontaneous remissions and exacerbations with significant morbidity. A novel corona...
32,271,603
Arch Iran Med
Dynamic Chest CT Evaluation in Three Cases of 2019 Novel Coronavirus Pneumonia.
A recent outbreak of pneumonia in Wuhan, China, was caused by the 2019 novel coronavirus (2019-nCoV). There have been some reports of imaging findings regarding the disease's characteristic features. Here, we report three cases of coronavirus disease 2019 (COVID-19) with dynamic pulmonary CT evaluation. The CT scan sho...
2019-novel coronavirus pneumonia;chest computed tomography;clinical characteristics;coronavirus disease 2019;dynamic evaluation
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Chen, Xing;Liu, Shuying;Zhang, Chunyi;Pu, Guimei;Sun, Jian;Shen, Juxin;Chen, Yefeng
10.34172/aim.2020.11
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Dynamic Chest CT Evaluation in Three Cases of 2019 Novel Coronavirus Pneumonia. [Abstract]: A recent outbreak of pneumonia in Wuhan, China, was caused by the 2019 novel coronavirus (2019-nCoV). There have been some reports of imaging findings regarding the disease's characteristic features. Here, we report thr...
32,526,763
Nephron
COVID-19 Experience in Hemodialysis Patients: A Cue for Therapeutic Heparin-Based Strategies?
In our opinion, the use of heparin could play a crucial role in these patients. In fact, recent studies have shown that heparin, the most commonly used anticoagulant during HD procedures, had anti-inflammatory properties and a direct antiviral action, due to its ability to prevent SARS-CoV-2 pseudovirus entry into host...
coronavirus disease 2019;hemodialysis;heparin
Journal Article
Pisani, Antonio;Rizzo, Manuela;Angelucci, Valentina;Riccio, Eleonora
10.1159/000508638
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 Experience in Hemodialysis Patients: A Cue for Therapeutic Heparin-Based Strategies? [Abstract]: In our opinion, the use of heparin could play a crucial role in these patients. In fact, recent studies have shown that heparin, the most commonly used anticoagulant during HD procedures, had anti-inflamma...
32,859,452
J Cardiol
Knowledge, perception, and level of confidence regarding COVID-19 care among healthcare workers involved in cardiovascular medicine: a web-based cross-sectional survey in Japan.
BACKGROUND: The pandemic of coronavirus disease 2019 (COVID-19) has a significant impact on daily practice in cardiovascular medicine. The preparedness of healthcare workers (HCWs) can affect the spread of infection and the maintenance of the healthcare system. This study aimed to investigate the knowledge, perception,...
covid-19;coronavirus;healthcare workers;preparedness
Journal Article
Kadoya, Yoshito;Zen, Kan;Wakana, Noriyuki;Yanishi, Kenji;Senoo, Keitaro;Nakanishi, Naohiko;Yamano, Tetsuhiro;Nakamura, Takeshi;Matoba, Satoaki
10.1016/j.jjcc.2020.07.029
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Knowledge, perception, and level of confidence regarding COVID-19 care among healthcare workers involved in cardiovascular medicine: a web-based cross-sectional survey in Japan. [Abstract]: BACKGROUND: The pandemic of coronavirus disease 2019 (COVID-19) has a significant impact on daily practice in cardiovascu...
32,535,142
Heart Rhythm
Behavior of the PR interval with increasing heart rate in patients with COVID-19.
BACKGROUND: Myriad manifestations of cardiovascular involvement have been described in patients with coronavirus disease 2019 (COVID-19), but there have been no reports of COVID-19 affecting the cardiac conduction system. The PR interval on the electrocardiogram (ECG) normally shortens with increasing heart rate (HR). ...
covid-19;coronavirus;electrocardiogram;pr interval;sars-cov-2
Journal Article
Pavri, Behzad B;Kloo, Juergen;Farzad, Darius;Riley, Joshua M
10.1016/j.hrthm.2020.06.009
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Behavior of the PR interval with increasing heart rate in patients with COVID-19. [Abstract]: BACKGROUND: Myriad manifestations of cardiovascular involvement have been described in patients with coronavirus disease 2019 (COVID-19), but there have been no reports of COVID-19 affecting the cardiac conduction sys...
32,412,418
JMIR Public Health Surveill
Global Sentiments Surrounding the COVID-19 Pandemic on Twitter: Analysis of Twitter Trends.
BACKGROUND: With the World Health Organization's pandemic declaration and government-initiated actions against coronavirus disease (COVID-19), sentiments surrounding COVID-19 have evolved rapidly. OBJECTIVE: This study aimed to examine worldwide trends of four emotions-fear, anger, sadness, and joy-and the narratives u...
covid-19;twitter;emotions;infodemic;pandemic;social sentiments
Journal Article;Research Support, Non-U.S. Gov't
Lwin, May Oo;Lu, Jiahui;Sheldenkar, Anita;Schulz, Peter Johannes;Shin, Wonsun;Gupta, Raj;Yang, Yinping
10.2196/19447
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Global Sentiments Surrounding the COVID-19 Pandemic on Twitter: Analysis of Twitter Trends. [Abstract]: BACKGROUND: With the World Health Organization's pandemic declaration and government-initiated actions against coronavirus disease (COVID-19), sentiments surrounding COVID-19 have evolved rapidly. OBJECTIVE:...
32,358,890
Dermatol Ther
Cutaneous side-effects of the potential COVID-19 drugs.
COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and other potential drugs have been studied for COVID19 treatment. We reviewed th...
covid-19;dermatology;side-effects;skin
Journal Article;Review
Tursen, Umit;Tursen, Belma;Lotti, Torello
10.1111/dth.13476
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Cutaneous side-effects of the potential COVID-19 drugs. [Abstract]: COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and ...
32,554,734
Cleve Clin J Med
Gastrointestinal manifestations of COVID-19.
Gastrointestinal (GI) symptoms are seen in patients with COVID-19. The prevalence could be as high as 50%, but most studies show ranges from 16% to 33%. Presenting with GI symptoms increases the risk of testing positive for SARs-CoV-2. Approximately 50% of patients with COVID-19 have detectable virus in their stool. Ha...
Journal Article
Ouali, Sara El;Achkar, Jean-Paul;Lashner, Bret;Regueiro, Miguel
10.3949/ccjm.87a.ccc049
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Gastrointestinal manifestations of COVID-19. [Abstract]: Gastrointestinal (GI) symptoms are seen in patients with COVID-19. The prevalence could be as high as 50%, but most studies show ranges from 16% to 33%. Presenting with GI symptoms increases the risk of testing positive for SARs-CoV-2. Approximately 50% ...
32,664,179
Medicine (Baltimore)
An uncommon manifestation of COVID-19 pneumonia on CT scan with small cavities in the lungs: A case report.
RATIONALE: Chest computed tomography (CT) scans play a key role in diagnosing and managing of COVID-19 pneumonia. The typical manifestations of COVID-19 pneumonia on a chest CT scan are ground glass opacities, consolidation, nodules, and linear opacities. It can be accompanied by a "crazy-paving" pattern, air bronchogr...
Case Reports;Journal Article
Chen, Jinqing;Peng, Song;Zhang, Bangjun;Liu, Zhifeng;Liu, Lang;Zhang, Wendy
10.1097/MD.0000000000021240
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: An uncommon manifestation of COVID-19 pneumonia on CT scan with small cavities in the lungs: A case report. [Abstract]: RATIONALE: Chest computed tomography (CT) scans play a key role in diagnosing and managing of COVID-19 pneumonia. The typical manifestations of COVID-19 pneumonia on a chest CT scan are groun...
32,487,856
Surg Laparosc Endosc Percutan Tech
Cost-Effective Filtrating Suction to Evacuate Surgical Smoke in Laparoscopic and Robotic Surgery During the COVID-19 Pandemic.
The wide and fast spread of COVID-19 around the world has led to a dramatic increase in the need for protection products both for carers and for populations. Surgical team protection includes a systematic screening of patients, wearing protection devices by all the operating staff, and adequate management of aerosols. ...
Journal Article;Technical Report
Ouzzane, Adil;Colin, Pierre
10.1097/SLE.0000000000000811
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cost-Effective Filtrating Suction to Evacuate Surgical Smoke in Laparoscopic and Robotic Surgery During the COVID-19 Pandemic. [Abstract]: The wide and fast spread of COVID-19 around the world has led to a dramatic increase in the need for protection products both for carers and for populations. Surgical team ...
32,449,333
Pol Arch Intern Med
Ability of the immune system to fight viruses highlighted by cytometry and T-cell receptor clonotype assessment: lessons taken before the coronavirus disease 2019 pandemic outbreak.
The intriguing aspects of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) are the high rate of spread and rapid progression of pneumonitis. Confronted with thousands of deaths daily worldwide, we have to quickly build the rationale behind the treatment, taking advantage of past analogues. When a new virus st...
Journal Article
Jaskula, Emilia;Lange, Andrzej
10.20452/pamw.15388
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Ability of the immune system to fight viruses highlighted by cytometry and T-cell receptor clonotype assessment: lessons taken before the coronavirus disease 2019 pandemic outbreak. [Abstract]: The intriguing aspects of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) are the high rate of spread and ...
32,984,400
Front Nutr
Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral M(pro) Protease Target Host Selenoproteins and Glutathione Synthesis?
Glutathione peroxidases (GPX), a family of antioxidant selenoenzymes, functionally link selenium and glutathione, which both show correlations with clinical outcomes in COVID-19. Thus, it is highly significant that cytosolic GPX1 has been shown to interact with an inactive C145A mutant of M(pro), the main cysteine prot...
covid-19;coronavirus;glutathione;glutathione peroxidase 1;protease;selenium;selenoprotein;thioredoxin reductase
Journal Article
Taylor, Ethan Will;Radding, Wilson
10.3389/fnut.2020.00143
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral M(pro) Protease Target Host Selenoproteins and Glutathione Synthesis? [Abstract]: Glutathione peroxidases (GPX), a family of antioxidant selenoenzymes, functionally link selenium and glutathione, which both show correlation...
32,679,348
J Allergy Clin Immunol Pract
The Challenges and Opportunities for Shared Decision Making Highlighted by COVID-19.
Shared decision making (SDM) is a management paradigm that empowers patients as partners in their own care in a bidirectional exchange of information and values, and optimize the decision-making process. During the current coronavirus disease 2019 pandemic, there is a greater need to encourage participation in the SDM ...
covid-19;decision aid;decisional conflict;sars-cov-2;shared decision making
Journal Article;Research Support, U.S. Gov't, P.H.S.;Review
Abrams, Elissa M;Shaker, Marcus;Oppenheimer, John;Davis, Ray S;Bukstein, Don A;Greenhawt, Matthew
10.1016/j.jaip.2020.07.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Challenges and Opportunities for Shared Decision Making Highlighted by COVID-19. [Abstract]: Shared decision making (SDM) is a management paradigm that empowers patients as partners in their own care in a bidirectional exchange of information and values, and optimize the decision-making process. During the...
33,075,530
Int J Infect Dis
COVID toes: where do we stand with the current evidence?
BACKGROUND: Numerous of cases of chilblains have been observed, mainly in young subjects with no or mild symptoms compatible with COVID-19. The pathophysiology of these lesions is still widely debated and an association with SARS-CoV-2 infection remains unconfirmed. OBJECTIVES: This paper focus on the unresolved issues...
covid toes;covid-19;rt-pcr;sars-cov-2;acral lesions;chilblains;pandemic;serology tests
Journal Article
Baeck, Marie;Herman, Anne
10.1016/j.ijid.2020.10.021
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: COVID toes: where do we stand with the current evidence? [Abstract]: BACKGROUND: Numerous of cases of chilblains have been observed, mainly in young subjects with no or mild symptoms compatible with COVID-19. The pathophysiology of these lesions is still widely debated and an association with SARS-CoV-2 infect...
32,795,997
J Med Internet Res
Rapid Implementation and Innovative Applications of a Virtual Intensive Care Unit During the COVID-19 Pandemic: Case Study.
BACKGROUND: The COVID-19 pandemic has necessitated a rapid increase of space in highly infectious disease intensive care units (ICUs). At Houston Methodist Hospital (HMH), a virtual intensive care unit (vICU) was used amid the COVID-19 outbreak. OBJECTIVE: The aim of this paper was to detail the novel adaptations and r...
covid-19;sars-cov-2;critical care;infection control;intensive care units;pandemics;telemedicine
Case Reports;Journal Article
Dhala, Atiya;Sasangohar, Farzan;Kash, Bita;Ahmadi, Nima;Masud, Faisal
10.2196/20143
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rapid Implementation and Innovative Applications of a Virtual Intensive Care Unit During the COVID-19 Pandemic: Case Study. [Abstract]: BACKGROUND: The COVID-19 pandemic has necessitated a rapid increase of space in highly infectious disease intensive care units (ICUs). At Houston Methodist Hospital (HMH), a v...
32,879,902
Glob Health Res Policy
The impact of air pollution on the incidence and mortality of COVID-19.
Air pollution is the most significant environmental risk factor for all-cause mortality, and it has caused substantial disability-adjusted life-years and economic loss. Air pollution intensified the mortality during past pandemics, Spanish flu in 1918 and SARS-CoV-1 in 2003. It increases host susceptibility and virulen...
air pollution;covid-19;household air pollution;particulate matter;sars-cov 2
Journal Article
Karan, Abhinav;Ali, Kabeer;Teelucksingh, Surujpal;Sakhamuri, Sateesh
10.1186/s41256-020-00167-y
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of air pollution on the incidence and mortality of COVID-19. [Abstract]: Air pollution is the most significant environmental risk factor for all-cause mortality, and it has caused substantial disability-adjusted life-years and economic loss. Air pollution intensified the mortality during past pandem...
33,072,657
Front Pediatr
Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19.
Objectives: The aim of this study was to assess the impact of the COVID-19 pandemic and population lockdown on pediatric ED consultations. Methods: A cross-sectional study on pediatric emergency department consultations before and during the current COVID-19 pandemic (March-May 2019 vs. March-May 2020) was performed in...
covid-19;appropriateness;children;emergency department;lockdown;overcrowding
Journal Article
Valitutti, Francesco;Zenzeri, Letizia;Mauro, Angela;Pacifico, Rosario;Borrelli, Micaela;Muzzica, Stefania;Boccia, Giovanni;Tipo, Vincenzo;Vajro, Pietro
10.3389/fped.2020.00521
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19. [Abstract]: Objectives: The aim of this study was to assess the impact of the COVID-19 pandemic and population lockdown on pediatric ED consultations. Methods: A cross-sectional study on pediatric emergency department con...
32,918,324
Diabetes Metab Res Rev
Reduction of hypoglycaemia, lifestyle modifications and psychological distress during lockdown following SARS-CoV-2 outbreak in type 1 diabetes.
AIMS: To assess changes in glucose metrics and their association with psychological distress and lifestyle changes in patients with type 1 diabetes (T1D) using flash glucose monitoring (FGM) during lockdown following severe acute respiratory syndrome coronavirus 2 outbreak. MATERIALS AND METHODS: Single-centre, observa...
covid-19;fgm;hypoglycaemia;lifestyle;lockdown;type 1 diabetes
Journal Article
Caruso, Irene;Di Molfetta, Sergio;Guarini, Francesca;Giordano, Fiorella;Cignarelli, Angelo;Natalicchio, Annalisa;Perrini, Sebastio;Leonardini, Anna;Giorgino, Francesco;Laviola, Luigi
10.1002/dmrr.3404
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reduction of hypoglycaemia, lifestyle modifications and psychological distress during lockdown following SARS-CoV-2 outbreak in type 1 diabetes. [Abstract]: AIMS: To assess changes in glucose metrics and their association with psychological distress and lifestyle changes in patients with type 1 diabetes (T1D) ...
32,781,471
Endoscopy
COVID-19 and endoscopic management of superficial gastrointestinal neoplastic lesions: a multinational cross-sectional survey.
INTRODUCTION: We aimed to report the impact of the pandemic lockdown period on the treatment and prognosis of superficial gastrointestinal neoplastic lesions. METHODS: A survey was completed by 11 centers from four continents regarding postponements during the early lockdown period of the pandemic, and the same period ...
Journal Article;Multicenter Study
Rodriguez-Carrasco, Marta;Albeniz, Eduardo;Bhandari, Pradeep;Beyna, Torsten;Bourke, Michael J;Min, Ahyeon;Chiu, Philip W Y;Chu, Simon;Yip, Hon Chi;Deprez, Pierre H;Emura, Fabian;Repici, Alessandro;Suzuki, Noriko;Yahagi, Naohisa;Kubosawa, Yoko;Hassan, Cesare;Dinis-Ribeiro, Mario
10.1055/a-1237-5221
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and endoscopic management of superficial gastrointestinal neoplastic lesions: a multinational cross-sectional survey. [Abstract]: INTRODUCTION: We aimed to report the impact of the pandemic lockdown period on the treatment and prognosis of superficial gastrointestinal neoplastic lesions. METHODS: A su...
32,499,157
Acad Radiol
Disposable Isolation Device to Reduce COVID-19 Contamination During CT Scanning.
RATIONALE AND OBJECTIVES: The use of chest computed tomography (CT) in the era of the COVID-19 pandemic raises concern regarding the transmission risks to patients and staff caused by CT room contamination. Meanwhile the Center for Disease Control guidance for air exchange in between patients may heavily impact workflo...
computed tomography;infection control / standards;patient isolation / instrumentation
Journal Article;Research Support, N.I.H., Extramural
Amalou, Amel;Turkbey, Baris;Xu, Sheng;Turkbey, Evrim;An, Peng;Carrafiello, Gianpaolo;Ierardi, Anna Maria;Suh, Robert;Amalou, Hayet;Wood, Bradford J
10.1016/j.acra.2020.05.017
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Disposable Isolation Device to Reduce COVID-19 Contamination During CT Scanning. [Abstract]: RATIONALE AND OBJECTIVES: The use of chest computed tomography (CT) in the era of the COVID-19 pandemic raises concern regarding the transmission risks to patients and staff caused by CT room contamination. Meanwhile t...
32,605,788
Injury
Development of an enhanced acute care surgery service in response to the COVID-19 global pandemic.
BACKGROUND: As the COVID-19 pandemic sweeps across the world, healthcare departments must adapt to meet the challenges of service provision and staff/patient protection. Unlike elective surgery, acute care surgery (ACS) workloads cannot be artificially reduced providing a unique challenge for administrators to balance ...
acute care surgery;covid-19;trauma
Journal Article
Mathur, Sachin;Jeremy Ng, Chung Fai;Koh, Fangju;Cai, Mingzhe;Palaniappan, Gautham;Linn, Yun Le;Lim, Huiling Linda;Lakshman, Ramu;Ling, Xiao Shuang;Chin, Sock Teng;Tan, Hiang Khoon
10.1016/j.injury.2020.06.040
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Development of an enhanced acute care surgery service in response to the COVID-19 global pandemic. [Abstract]: BACKGROUND: As the COVID-19 pandemic sweeps across the world, healthcare departments must adapt to meet the challenges of service provision and staff/patient protection. Unlike elective surgery, acute...
32,713,118
J Dig Dis
Liver damage at admission is an independent prognostic factor for COVID-19.
OBJECTIVE: Abnormal liver function is a common form of extra-pulmonary organ damage in patients with coronavirus disease 2019 (COVID-19). Patients with severe COVID-19 have a higher probability and progression of liver injury than those without severe disease. We aimed to evaluate the prognosis of liver injury in patie...
covid-19;liver injury;prognosis
Journal Article
Chen, Liu Ying;Chu, Hui Kuan;Bai, Tao;Tu, Sheng Jin;Wei, Yuan;Li, Zhong Lin;Hu, Li Lin;Zhu, Rui;Zhang, Lei;Han, Chao Qun;Xiao, Li;He, Qi;Song, Jun;Liu, Wei Hua;Zhu, Qing Jing;Chen, Hua;Yang, Ling;Hou, Xiao Hua
10.1111/1751-2980.12925
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Liver damage at admission is an independent prognostic factor for COVID-19. [Abstract]: OBJECTIVE: Abnormal liver function is a common form of extra-pulmonary organ damage in patients with coronavirus disease 2019 (COVID-19). Patients with severe COVID-19 have a higher probability and progression of liver inju...
32,360,444
Clin Microbiol Infect
Balancing evidence and frontline experience in the early phases of the COVID-19 pandemic: current position of the Italian Society of Anti-infective Therapy (SITA) and the Italian Society of Pulmonology (SIP).
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become epidemic in Italy and other European countries. The disease spectrum ranges from asymptomatic/mildly symptomatic presentations to acute respiratory failure. At...
covid-19;coronavirus;pneumonia;sars-cov-2;therapy
Journal Article;Review
Bassetti, M;Giacobbe, D R;Aliberti, S;Barisione, E;Centanni, S;De Rosa, F G;Di Marco, F;Gori, A;Granata, G;Mikulska, M;Petrosillo, N;Richeldi, L;Santus, P;Tascini, C;Vena, A;Viale, P;Blasi, F
10.1016/j.cmi.2020.04.031
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Balancing evidence and frontline experience in the early phases of the COVID-19 pandemic: current position of the Italian Society of Anti-infective Therapy (SITA) and the Italian Society of Pulmonology (SIP). [Abstract]: BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative ...
32,525,549
JAMA Netw Open
Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis.
Importance: Coronavirus disease 2019 (COVID-19) is a global pandemic and can involve the gastrointestinal (GI) tract, including symptoms like diarrhea and shedding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in feces. Objective: To provide a pooled estimate of GI symptoms, liver enzyme levels ou...
Journal Article;Meta-Analysis;Systematic Review
Parasa, Sravanthi;Desai, Madhav;Thoguluva Chandrasekar, Viveksandeep;Patel, Harsh K;Kennedy, Kevin F;Roesch, Thomas;Spadaccini, Marco;Colombo, Matteo;Gabbiadini, Roberto;Artifon, Everson L A;Repici, Alessandro;Sharma, Prateek
10.1001/jamanetworkopen.2020.11335
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis. [Abstract]: Importance: Coronavirus disease 2019 (COVID-19) is a global pandemic and can involve the gastrointestinal (GI) tract, including symptoms like diarrhea a...
32,448,879
Recenti Prog Med
[CoViD-19 in Italy: homeless population needs protection.]
Italy is one of the most affected countries by the new coronavirus (CoViD-19) pandemic. In the country, there are an estimated 49,000-52,000 homeless people. People experiencing homelessness are among the potentially most vulnerable groups to the CoViD-19. Despite this, in Italy there is a worrying delay in implementat...
Editorial
Barbieri, Alberto
10.1701/3366.33410
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [CoViD-19 in Italy: homeless population needs protection.] [Abstract]: Italy is one of the most affected countries by the new coronavirus (CoViD-19) pandemic. In the country, there are an estimated 49,000-52,000 homeless people. People experiencing homelessness are among the potentially most vulnerable groups ...
32,458,370
Am J Cardiovasc Drugs
Management of Outpatient Warfarin Therapy amid COVID-19 Pandemic: A Practical Guide.
Many healthcare resources have been and continue to be allocated to the management of patients with COVID-19. Therefore, the ongoing care of patients receiving oral anticoagulation with warfarin is likely to be compromised amid this unprecedented crisis. This article discusses a stepwise algorithm for the management of...
Journal Article;Review
Kow, Chia Siang;Sunter, Wendy;Bain, Amie;Zaidi, Syed Tabish Razi;Hasan, Syed Shahzad
10.1007/s40256-020-00415-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of Outpatient Warfarin Therapy amid COVID-19 Pandemic: A Practical Guide. [Abstract]: Many healthcare resources have been and continue to be allocated to the management of patients with COVID-19. Therefore, the ongoing care of patients receiving oral anticoagulation with warfarin is likely to be com...
32,731,913
BMB Rep
Immunomodulatory effect of mesenchymal stem cells and mesenchymal stem-cell-derived exosomes for COVID-19 treatment.
The world has witnessed unimaginable damage from the coronavirus disease-19 (COVID-19) pandemic. Because the pandemic is growing rapidly, it is important to consider diverse treatment options to effectively treat people worldwide. Since the immune system is at the hub of the infection, it is essential to regulate the d...
Journal Article;Review
Jayaramayya, Kaavya;Mahalaxmi, Iyer;Subramaniam, Mohana Devi;Raj, Neethu;Dayem, Ahmed Abdal;Lim, Kyung Min;Kim, Se Jong;An, Jong Yub;Lee, Yoonjoo;Choi, Yujin;Raj, Arthi;Cho, Ssang-Goo;Vellingiri, Balachandar
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Immunomodulatory effect of mesenchymal stem cells and mesenchymal stem-cell-derived exosomes for COVID-19 treatment. [Abstract]: The world has witnessed unimaginable damage from the coronavirus disease-19 (COVID-19) pandemic. Because the pandemic is growing rapidly, it is important to consider diverse treatmen...
32,717,195
J Theor Biol
Optimal strategies for vaccination and social distancing in a game-theoretic epidemiologic model.
For various infectious diseases, vaccination has become a major intervention strategy. However, the importance of social distancing has recently been highlighted during the ongoing COVID-19 pandemic. In the absence of vaccination, or when vaccine efficacy is poor, social distancing may help to curb the spread of new vi...
game theory;infectious disease;nash;social-distancing;vaccine
Journal Article;Research Support, Non-U.S. Gov't
Choi, Wongyeong;Shim, Eunha
10.1016/j.jtbi.2020.110422
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Optimal strategies for vaccination and social distancing in a game-theoretic epidemiologic model. [Abstract]: For various infectious diseases, vaccination has become a major intervention strategy. However, the importance of social distancing has recently been highlighted during the ongoing COVID-19 pandemic. I...
32,405,544
Eur Urol Focus
Changes in Urology After the First Wave of the COVID-19 Pandemic.
The COVID-19 pandemic has changed the world. Urology needs to overcome these challenges. Our duty is to provide care under any circumstances and our privilege is to re-examine and advance our field. The use of novel communication and health technologies will ensure safety while maintaining high-quality care.
Editorial
Margel, David;Ber, Yaara
10.1016/j.euf.2020.05.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Changes in Urology After the First Wave of the COVID-19 Pandemic. [Abstract]: The COVID-19 pandemic has changed the world. Urology needs to overcome these challenges. Our duty is to provide care under any circumstances and our privilege is to re-examine and advance our field. The use of novel communication and...
32,500,409
Rheumatol Int
Implications of COVID-19 in pediatric rheumatology.
COVID-19 (coronavirus disease 2019) pandemic caused by SARS-CoV-2, is a global public health issue threatening millions of lives worldwide. Although the infection is mild in most of the affected individuals, it may cause severe clinical manifestations such as acute respiratory distress syndrome or cytokine storm leadin...
covid-19;covid-19 virus;familial mediterranean fever;rheumatic disease;sars-cov-2;systemic lupus erythematosus
Journal Article;Review
Batu, Ezgi Deniz;Ozen, Seza
10.1007/s00296-020-04612-6
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Implications of COVID-19 in pediatric rheumatology. [Abstract]: COVID-19 (coronavirus disease 2019) pandemic caused by SARS-CoV-2, is a global public health issue threatening millions of lives worldwide. Although the infection is mild in most of the affected individuals, it may cause severe clinical manifestat...
32,296,168
Nat Med
Temporal dynamics in viral shedding and transmissibility of COVID-19.
We report temporal patterns of viral shedding in 94 patients with laboratory-confirmed COVID-19 and modeled COVID-19 infectiousness profiles from a separate sample of 77 infector-infectee transmission pairs. We observed the highest viral load in throat swabs at the time of symptom onset, and inferred that infectiousnes...
Journal Article;Research Support, Non-U.S. Gov't
He, Xi;Lau, Eric H Y;Wu, Peng;Deng, Xilong;Wang, Jian;Hao, Xinxin;Lau, Yiu Chung;Wong, Jessica Y;Guan, Yujuan;Tan, Xinghua;Mo, Xiaoneng;Chen, Yanqing;Liao, Baolin;Chen, Weilie;Hu, Fengyu;Zhang, Qing;Zhong, Mingqiu;Wu, Yanrong;Zhao, Lingzhai;Zhang, Fuchun;Cowling, Benjamin J;Li, Fang;Leung, Gabriel M
10.1038/s41591-020-0869-5
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Temporal dynamics in viral shedding and transmissibility of COVID-19. [Abstract]: We report temporal patterns of viral shedding in 94 patients with laboratory-confirmed COVID-19 and modeled COVID-19 infectiousness profiles from a separate sample of 77 infector-infectee transmission pairs. We observed the highe...
32,618,917
J Bone Joint Surg Am
Mortality Rates of Patients with Proximal Femoral Fracture in a Worldwide Pandemic: Preliminary Results of the Spanish HIP-COVID Observational Study.
BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), in December 2019 in Wuhan, People's Republic of China, has developed into an unprecedented pandemic with enormous pressure on health-care providers around the world. A higher mortalit...
Journal Article;Multicenter Study;Observational Study
Munoz Vives, Josep Maria;Jornet-Gibert, Montsant;Camara-Cabrera, J;Esteban, Pedro L;Brunet, Laia;Delgado-Flores, Luis;Camacho-Carrasco, P;Torner, P;Marcano-Fernandez, Francesc
10.2106/JBJS.20.00686
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Mortality Rates of Patients with Proximal Femoral Fracture in a Worldwide Pandemic: Preliminary Results of the Spanish HIP-COVID Observational Study. [Abstract]: BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), in December ...
32,415,888
Eur J Neurol
Ischaemic stroke in the time of coronavirus disease 2019.
BACKGROUND AND PURPOSE: Stroke assistance is facing changes and new challenges since COVID-19 became pandemic. A variation on the patient influx might be one of the greater concerns, due to fewer people coming to emergency departments or coming too late. However, no data quantifying this have been published until now. ...
covid-19;stroke
Journal Article
Tejada Meza, H;Lambea Gil, A;Sancho Saldana, A;Villar Yus, C;Pardinas Baron, B;Sagarra Mur, D;Marta Moreno, J
10.1111/ene.14327
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Ischaemic stroke in the time of coronavirus disease 2019. [Abstract]: BACKGROUND AND PURPOSE: Stroke assistance is facing changes and new challenges since COVID-19 became pandemic. A variation on the patient influx might be one of the greater concerns, due to fewer people coming to emergency departments or com...
32,512,349
J Crit Care
Clinically significant anticardiolipin antibodies associated with COVID-19.
The novel coronavirus strain known as SARS-CoV-2 has rapidly spread around the world creating distinct challenges to the healthcare workforce. Coagulopathy contributing to significant morbidity in critically ill patients with SARS-CoV-2 has now been well documented. We discuss two cases selected from patients requiring...
anticardiolipin;antiphospholipid syndrome;coagulopathy;coronarvirus;covid-19;critical care;icu;infarct;peripheral arterial disease;sars-cov-2;stroke
Case Reports
Hossri, Sami;Shadi, Mahmoud;Hamarsha, Zaid;Schneider, Rick;El-Sayegh, Dany
10.1016/j.jcrc.2020.05.017
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Clinically significant anticardiolipin antibodies associated with COVID-19. [Abstract]: The novel coronavirus strain known as SARS-CoV-2 has rapidly spread around the world creating distinct challenges to the healthcare workforce. Coagulopathy contributing to significant morbidity in critically ill patients wi...
32,938,602
BMJ Open
Support for mobilising medical students to join the COVID-19 pandemic emergency healthcare workforce: a cross-sectional questionnaire survey.
OBJECTIVE: To identify what motivates medical students to join a pandemic emergency healthcare workforce. DESIGN: Cross-sectional study. SETTING: Aalborg University, Denmark. PARTICIPANTS: All medical students. MAIN OUTCOME MEASURES: Motivational points as perceived by the students to be important. Demographic characte...
health policy;health services administration & management;medical education & training
Journal Article
Astorp, Mike Saederup;Sorensen, Gustav Valentin Blichfeldt;Rasmussen, Sten;Emmersen, Jeppe;Erbs, Alexander Wolfhagen;Andersen, Stig
10.1136/bmjopen-2020-039082
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Support for mobilising medical students to join the COVID-19 pandemic emergency healthcare workforce: a cross-sectional questionnaire survey. [Abstract]: OBJECTIVE: To identify what motivates medical students to join a pandemic emergency healthcare workforce. DESIGN: Cross-sectional study. SETTING: Aalborg Uni...
32,423,553
Vascul Pharmacol
Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection.
Angiotensin-converting enzyme (ACE) and its homologue, ACE2, have been mostly associated with hypertensive disorder. However, recent pandemia of SARS-CoV-2 has put these proteins at the center of attention, as this virus has been shown to exploit ACE2 protein to enter cells. Clear difference in the response of affected...
ace;angiotensin-converting enzyme;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Review
Ghafouri-Fard, Soudeh;Noroozi, Rezvan;Omrani, Mir Davood;Branicki, Wojciech;Pospiech, Ewelina;Sayad, Arezou;Pyrc, Krzysztof;Labaj, Pawel P;Vafaee, Reza;Taheri, Mohammad;Sanak, Marek
10.1016/j.vph.2020.106680
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection. [Abstract]: Angiotensin-converting enzyme (ACE) and its homologue, ACE2, have been mostly associated with hypertensive disorder. However, recent pandemia of SARS-Co...
32,288,415
J Shanghai Jiaotong Univ Sci
Prediction of COVID-19 Outbreak in China and Optimal Return Date for University Students Based on Propagation Dynamics.
On 12 December 2019, a novel coronavirus disease, named COVID-19, began to spread around the world from Wuhan, China. It is useful and urgent to consider the future trend of this outbreak. We establish the 4+1 penta-group model to predict the development of the COVID-19 outbreak. In this model, we use the collected dat...
analytic hierarchy process (ahp);epidemic dynamics model, nonlinear least squares;technique for order preference by similarity to an ideal solution (topsis)
Journal Article
Huang, Ganyu;Pan, Qiaoyi;Zhao, Shuangying;Gao, Yucen;Gao, Xiaofeng
10.1007/s12204-020-2167-2
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Prediction of COVID-19 Outbreak in China and Optimal Return Date for University Students Based on Propagation Dynamics. [Abstract]: On 12 December 2019, a novel coronavirus disease, named COVID-19, began to spread around the world from Wuhan, China. It is useful and urgent to consider the future trend of this ...
32,707,160
Food Chem Toxicol
An overview of the safety assessment of medicines currently used in the COVID-19 disease treatment.
On 11(th) March 2020, the pandemic of the new coronavirus was declared by the World Health Organization. At the moment, there are no new registered medicines that can effectively treat the coronavirus infection. However, a number of ongoing clinical trials are investigating the efficacy and safety of the medicines whic...
covid-19;medicines;sars-cov-2;therapy;toxicity
Journal Article;Review
Javorac, Dragana;Grahovac, Lazar;Manic, Luka;Stojilkovic, Nikola;Andelkovic, Milena;Bulat, Zorica;Dukic-Cosic, Danijela;Curcic, Marijana;Djordjevic, Aleksandra Buha
10.1016/j.fct.2020.111639
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: An overview of the safety assessment of medicines currently used in the COVID-19 disease treatment. [Abstract]: On 11(th) March 2020, the pandemic of the new coronavirus was declared by the World Health Organization. At the moment, there are no new registered medicines that can effectively treat the coronaviru...
33,004,206
Injury
Rethinking Trauma Hospital Services in one of Spain's Largest University Hospitals during the COVID-19 pandemic. How can we organize and help? Our experience.
INTRODUCTION: The severe disruptions caused by the SARS-CoV-2 coronavirus have necessitated a redistribution of resources to meet hospitals' current service needs during this pandemic. The aim is to share our experiences and outcomes during the first month of the Covid-19 pandemic, based on the strategies recommended a...
covid-19;organization;orthopaedic;pandemic;trauma
Journal Article
Nunez, Jorge H;Porcel, Juan Antonio;Pijoan, Joan;Batalla, Lledo;Teixidor, Jordi;Guerra-Farfan, Ernesto;Minguell, Joan
10.1016/j.injury.2020.09.055
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rethinking Trauma Hospital Services in one of Spain's Largest University Hospitals during the COVID-19 pandemic. How can we organize and help? Our experience. [Abstract]: INTRODUCTION: The severe disruptions caused by the SARS-CoV-2 coronavirus have necessitated a redistribution of resources to meet hospitals'...
32,849,073
Front Psychol
Social Distancing and Stigma: Association Between Compliance With Behavioral Recommendations, Risk Perception, and Stigmatizing Attitudes During the COVID-19 Outbreak.
Introduction: Following behavioral recommendations is key to successful containment of the COVID-19 pandemic. Therefore, it is important to identify causes and patterns of non-compliance in the population to further optimize risk and health communication. Methods: A total of 157 participants [80% female; mean age = 27....
covid-19;cross-sectional;infection prevention;latent class analysis;public health;risk communication;stigma
Journal Article
Tomczyk, Samuel;Rahn, Maxi;Schmidt, Silke
10.3389/fpsyg.2020.01821
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Social Distancing and Stigma: Association Between Compliance With Behavioral Recommendations, Risk Perception, and Stigmatizing Attitudes During the COVID-19 Outbreak. [Abstract]: Introduction: Following behavioral recommendations is key to successful containment of the COVID-19 pandemic. Therefore, it is impo...
32,639,236
Anesthesiology
Differential Ventilation Using Flow Control Valves as a Potential Bridge to Full Ventilatory Support during the COVID-19 Crisis.
BACKGROUND: During the COVID-19 pandemic, ventilator sharing was suggested to increase availability of mechanical ventilation. The safety and feasibility of ventilator sharing is unknown. METHODS: A single ventilator in pressure control mode was used with flow control valves to simultaneously ventilate two patients wit...
Journal Article
Levin, Matthew A;Shah, Anjan;Shah, Ronak;Kane, Erica;Zhou, George;Eisenkraft, James B;Chen, Martin D
10.1097/ALN.0000000000003473
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Differential Ventilation Using Flow Control Valves as a Potential Bridge to Full Ventilatory Support during the COVID-19 Crisis. [Abstract]: BACKGROUND: During the COVID-19 pandemic, ventilator sharing was suggested to increase availability of mechanical ventilation. The safety and feasibility of ventilator sh...
32,985,317
J Intensive Care Med
Ocular Complications in the Prone Position in the Critical Care Setting: The COVID-19 Pandemic.
PURPOSE: Ocular complications are common in the critical care setting but are frequently missed due to the focus on life-saving organ support. The SARS-CoV-2 (COVID-19) pandemic has led to a surge in critical care capacity and prone positioning practices which may increase the risk of ocular complications. This article...
covid-19;critical care;eye care;eye disorders;ocular complications;prone positioning
Journal Article;Review
Sanghi, Priyanka;Malik, Mohsan;Hossain, Ibtesham T;Manzouri, Bita
10.1177/0885066620959031
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Ocular Complications in the Prone Position in the Critical Care Setting: The COVID-19 Pandemic. [Abstract]: PURPOSE: Ocular complications are common in the critical care setting but are frequently missed due to the focus on life-saving organ support. The SARS-CoV-2 (COVID-19) pandemic has led to a surge in cri...
32,856,034
Clin Infect Dis
Patient Characteristics and Outcomes of 11,721 Patients with COVID19 Hospitalized Across the United States.
BACKGROUND: As COVID-19 disseminates throughout the US, a better understanding of patient characteristics associated with hospitalization, morbidity and mortality in diverse geographic regions is essential. METHODS: Hospital chargemaster data on adult patients with COVID-19 admitted to 245 hospitals across 38 states be...
covid-19;sars-cov-2;hydroxychloroquine;observational study;remdesivir
Journal Article
Fried, Michael W;Crawford, Julie M;Mospan, Andrea R;Watkins, Stephanie E;Munoz Hernandez, Breda;Zink, Richard C;Elliott, Sherry;Burleson, Kyle;Landis, Charles;Reddy, K Rajender;Brown, Robert S
10.1093/cid/ciaa1268
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Patient Characteristics and Outcomes of 11,721 Patients with COVID19 Hospitalized Across the United States. [Abstract]: BACKGROUND: As COVID-19 disseminates throughout the US, a better understanding of patient characteristics associated with hospitalization, morbidity and mortality in diverse geographic region...
32,758,712
Virology
A reverse-transcription recombinase-aided amplification assay for the rapid detection of N gene of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).
The current outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in China firstly. A rapid, highly sensitive, specific, and simple operational method was needed for the detection of SARS-CoV-2. Here, we established a real-time reverse-trans...
nucleocapsid protein;real-time rt-pcr;real-time rt-raa;sars-cov-2
Comparative Study;Evaluation Study;Journal Article;Research Support, Non-U.S. Gov't
Wu, Tao;Ge, Yiyue;Zhao, Kangchen;Zhu, Xiaojuan;Chen, Yin;Wu, Bin;Zhu, Fengcai;Zhu, Baoli;Cui, Lunbiao
10.1016/j.virol.2020.07.006
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A reverse-transcription recombinase-aided amplification assay for the rapid detection of N gene of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). [Abstract]: The current outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was rep...
32,649,538
J Craniofac Surg
Gustatory Dysfunction as an Early Symptom in COVID-19 Screening.
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from Wuhan, China in December 2019 leads to the present coronavirus disease 2019 (COVID-19) pandemic. The various symptoms identified for COVID-19 are fever, dry cough, sore throat, dyspnea, fatigue, myalgia, and headache. Olfactory and gustat...
Journal Article
Harikrishnan, Pandurangan
10.1097/SCS.0000000000006797
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Gustatory Dysfunction as an Early Symptom in COVID-19 Screening. [Abstract]: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from Wuhan, China in December 2019 leads to the present coronavirus disease 2019 (COVID-19) pandemic. The various symptoms identified for COVID-19 are fever,...
32,998,840
Radiography (Lond)
Typical CT findings of COVID-19 pneumonia in patients presenting with repetitive negative RT-PCR.
Multiple polymerase chain reaction (RT-PCR) is considered the gold standard diagnostic investigation for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19). However, false negative multiple polymerase chain reaction (RT-PCR) results can be diagnostically challen...
covid-19;chest ct;repeated negative rt-pcr;sars-cov-2;serological platforms
Case Reports
Brogna, B;Bignardi, E;Brogna, C;Alberigo, M;Grappone, M;Megliola, A;Salvatore, P;Fontanella, G;Mazza, E M;Musto, L
10.1016/j.radi.2020.09.012
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Typical CT findings of COVID-19 pneumonia in patients presenting with repetitive negative RT-PCR. [Abstract]: Multiple polymerase chain reaction (RT-PCR) is considered the gold standard diagnostic investigation for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 201...
32,583,171
Infection
Utility of CT scan in patients with initial negative PCR for SARS-CoV2: a report of three cases.
PCR-based viral RNA to confirm the diagnosis of SARS-CoV-2 infection has a sensitivity of around 70%. We report three cases of patients with negative initial PCR and CT scan lesions that led us to suspect COVID-19, but which one(s) are really COVID-19?
covid-19;ct scan;coronavirus;mycoplasma pneumoniae;sars-cov2
Case Reports;Journal Article
Bouiller, Kevin;Humbert, Sebastien;Payet-Revest, Camille;Brunel, Anne-Sophie;Mareshal, Adrien;Lepiller, Quentin;Grillet, Franck;Chirouze, Catherine
10.1007/s15010-020-01467-8
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Utility of CT scan in patients with initial negative PCR for SARS-CoV2: a report of three cases. [Abstract]: PCR-based viral RNA to confirm the diagnosis of SARS-CoV-2 infection has a sensitivity of around 70%. We report three cases of patients with negative initial PCR and CT scan lesions that led us to suspe...
32,319,442
Recenti Prog Med
[Clinical ethics recommendations for the allocation of intensive care treatments, in exceptional, resource-limited circumstances.]
On February 21st, 2020 the first case of severe acute respiratory syndrome due to the coronavirus 2 (SARS-CoV-2) causing the CoViD-19 disease, was identified in Italy. In the following days, despite the restrictive public health measures aimed to avoid the infection's spread, the number of cases increased. As of March ...
Journal Article
Riccioni, Luigi;Bertolini, Guido;Giannini, Alberto;Vergano, Marco;Gristina, Giuseppe;Livigni, Sergio;Mistraletti, Giovanni;Petrini Gruppo di Lavoro Siaarti-Societa Italiana di Anestesia Analgesia Rianimazione E Terapia Intensiva, Flavia
10.1701/3347.33183
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Clinical ethics recommendations for the allocation of intensive care treatments, in exceptional, resource-limited circumstances.] [Abstract]: On February 21st, 2020 the first case of severe acute respiratory syndrome due to the coronavirus 2 (SARS-CoV-2) causing the CoViD-19 disease, was identified in Italy. ...
32,857,878
Am J Hematol
Thrombosis in COVID-19.
Thrombotic complications are frequent in COVID-19 and contribute significantly to mortality and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be upregulated in COVID-19. These include immune-mediated thrombotic mechanisms, complement activation, macrophage activation syndrome, antipho...
Journal Article;Research Support, N.I.H., Extramural;Review
Hanff, Thomas C;Mohareb, Amir M;Giri, Jay;Cohen, Jordana B;Chirinos, Julio A
10.1002/ajh.25982
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Thrombosis in COVID-19. [Abstract]: Thrombotic complications are frequent in COVID-19 and contribute significantly to mortality and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be upregulated in COVID-19. These include immune-mediated thrombotic mechanisms, complement activa...
32,603,205
OMICS
Post-Coronavirus Disease 2019 Health Care and University: From Efficiency to Resilience.
After the initial emergency responses deployed to control the coronavirus disease 2019 (COVID-19) pandemic in the first half of 2020, we should now start thinking about long-term strategies and concepts for pandemic and disaster governance such as resilience. In this context, COVID-19 health care and education are espe...
covid-19;disaster and crisis governance;ecology;health care;higher education;resilience
Journal Article
Akar, Ismail
10.1089/omi.2020.0111
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Post-Coronavirus Disease 2019 Health Care and University: From Efficiency to Resilience. [Abstract]: After the initial emergency responses deployed to control the coronavirus disease 2019 (COVID-19) pandemic in the first half of 2020, we should now start thinking about long-term strategies and concepts for pan...
32,576,346
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
[Value of neutrophil-to-lymphocyte ratio in the classification diagnosis of coronavirus disease 2019].
OBJECTIVE: To investigate the clinical significance of neutrophil-to-lymphocyte ratio (NLR) in classification of patients with coronavirus disease 2019 (COVID-19). METHODS: A retrospective analysis was performed on 72 patients with COVID-19 admitted to the critical ward of Cancer Center of Union Hospital Affiliated to ...
Journal Article
Fei, Mingming;Tong, Fei;Tao, Xiaogen;Wang, Jinquan
10.3760/cma.j.cn121430-20200413-00506
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [Value of neutrophil-to-lymphocyte ratio in the classification diagnosis of coronavirus disease 2019]. [Abstract]: OBJECTIVE: To investigate the clinical significance of neutrophil-to-lymphocyte ratio (NLR) in classification of patients with coronavirus disease 2019 (COVID-19). METHODS: A retrospective analysi...
32,760,127
PLoS One
COVID-19-related perceptions, context and attitudes of adults with chronic conditions: Results from a cross-sectional survey nested in the ComPaRe e-cohort.
BACKGROUND: To avoid a surge of demand on the healthcare system due to the COVID-19 pandemic, we must reduce transmission to individuals with chronic conditions who are at risk of severe illness with COVID-19. We aimed at understanding the perceptions, context and attitudes of individuals with chronic conditions during...
Journal Article;Research Support, Non-U.S. Gov't
Tran, Viet-Thi;Ravaud, Philippe
10.1371/journal.pone.0237296
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19-related perceptions, context and attitudes of adults with chronic conditions: Results from a cross-sectional survey nested in the ComPaRe e-cohort. [Abstract]: BACKGROUND: To avoid a surge of demand on the healthcare system due to the COVID-19 pandemic, we must reduce transmission to individuals with ...
33,039,212
Am J Emerg Med
Development and validation of a knowledge-driven risk calculator for critical illness in COVID-19 patients.
Facing the novel coronavirus disease (COVID-19) pandemic, evidence to inform decision-making at all care levels is essential. Based on the results of a study by Petrilli et al., we have developed a calculator using patient data at admission to predict critical illness (intensive care, mechanical ventilation, hospice ca...
Journal Article;Validation Study
Cahan, Amos;Gottesman, Tamar;Katz, Michal Tzuchman;Masad, Roee;Azulay, Gal;Dicker, Dror;Zeidman, Aliza;Berkov, Evgeny;Tadmor, Boaz;Lev, Shaul
10.1016/j.ajem.2020.09.051
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Development and validation of a knowledge-driven risk calculator for critical illness in COVID-19 patients. [Abstract]: Facing the novel coronavirus disease (COVID-19) pandemic, evidence to inform decision-making at all care levels is essential. Based on the results of a study by Petrilli et al., we have devel...
32,345,566
J Arthroplasty
Economic Recovery After the COVID-19 Pandemic: Resuming Elective Orthopedic Surgery and Total Joint Arthroplasty.
BACKGROUND: The economic effects of the COVID-19 crisis are not like anything the U.S. health care system has ever experienced. METHODS: As we begin to emerge from the peak of the COVID-19 pandemic, we need to plan the sustainable resumption of elective procedures. We must first ensure the safety of our patients and su...
covid-19;econonomics;elective orthopaedic surgery;patient demand;technology and innovation;volume
Journal Article
O'Connor, Casey M;Anoushiravani, Afshin A;DiCaprio, Matthew R;Healy, William L;Iorio, Richard
10.1016/j.arth.2020.04.038
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Economic Recovery After the COVID-19 Pandemic: Resuming Elective Orthopedic Surgery and Total Joint Arthroplasty. [Abstract]: BACKGROUND: The economic effects of the COVID-19 crisis are not like anything the U.S. health care system has ever experienced. METHODS: As we begin to emerge from the peak of the COVID...
32,510,978
Arterioscler Thromb Vasc Biol
Overcoming Barriers: The Endothelium As a Linchpin of Coronavirus Disease 2019 Pathogenesis?
OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a global pandemic involving >5 500 000 cases worldwide as of May 26, 2020. The culprit is the severe acute respiratory syndrome coronavirus-2, which invades cells by binding to ACE2 (angiotensin-converting enzyme 2). While the majority of patients mount an appropriate a...
biomarkers;cardiac injury;coronavirus;endothelium;pandemic
Journal Article;Research Support, Non-U.S. Gov't;Review
Gustafson, Dakota;Raju, Sneha;Wu, Ruilin;Ching, Crizza;Veitch, Shawn;Rathnakumar, Kumaragurubaran;Boudreau, Emilie;Howe, Kathryn L;Fish, Jason E
10.1161/ATVBAHA.120.314558
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Overcoming Barriers: The Endothelium As a Linchpin of Coronavirus Disease 2019 Pathogenesis? [Abstract]: OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a global pandemic involving >5 500 000 cases worldwide as of May 26, 2020. The culprit is the severe acute respiratory syndrome coronavirus-2, which invades...
32,611,687
J Immunother Cancer
On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19.
The present review summarizes up-to-date evidence addressing the frequently discussed clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer patients with viral infections, including AIDS, hepatitis B and C, progressive multifocal leukoencephalopathy, influenza, and COVID-19. In detai...
t-lymphocytes;immune evation;review;tumor escape;vaccination
Journal Article;Review
Gambichler, Thilo;Reuther, Judith;Scheel, Christina H;Becker, Jurgen Christian
10.1136/jitc-2020-001145
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19. [Abstract]: The present review summarizes up-to-date evidence addressing the frequently discussed clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer patients with viral infect...
32,773,727
Korean J Anesthesiol
Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry. Two case reports.
Background: COVID-19-associated coagulopathy is most often characterized by elevated D-dimer, interleukin-6 and plasma fibrinogen concentration as well as hypercoagulability in thromboelastometry with increase clot firmness in EXTEM, INTEM and FIBTEM. Clinically, it strikes with a very high incidence of thrombosis, in ...
anticoagulation;covid-19;coagulopathy;hypercoagulability;thromboelastometry;thrombosis
Journal Article
Kong, Robert;Hutchinson, Nevil;Gorlinger, Klaus
10.4097/kja.20327
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Hyper- and hypocoagulability in COVID-19 as assessed by thromboelastometry. Two case reports. [Abstract]: Background: COVID-19-associated coagulopathy is most often characterized by elevated D-dimer, interleukin-6 and plasma fibrinogen concentration as well as hypercoagulability in thromboelastometry with incr...
32,837,592
Rheuma Plus
[The Gastein Healing Gallery and a Potential Risk of Viral Infections in the Treatment Area].
The SARS-CoV2 has infected millions of humans worldwide in the past few months and hundreds of thousands have died as a result of an infection. The end of the pandemic is not in sight and many people are anxious of becoming infected in different settings. The Gastein Healing Gallery (GHG) is a unique outpatient facilit...
covid-19;climatic factors;immune system;low dose radon hyperthermia;virus transmission
English Abstract;Journal Article
Offenbacher, M;Holzl, B;Gaisberger, M;Untner, H;Wurzner, R
10.1007/s12688-020-00350-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [The Gastein Healing Gallery and a Potential Risk of Viral Infections in the Treatment Area]. [Abstract]: The SARS-CoV2 has infected millions of humans worldwide in the past few months and hundreds of thousands have died as a result of an infection. The end of the pandemic is not in sight and many people are a...
33,051,827
Infect Dis Ther
Early Treatment of COVID-19 Disease: A Missed Opportunity.
Antivirals have demonstrated efficacy in treating other infectious diseases in early stages of disease, reducing morbidity, mortality, and the likelihood of onward transmission. At the time of writing, more than 1900 clinical trials are registered globally to assess the efficacy and safety of candidate therapeutics for...
covid-19;clinical trials;early treatment;treatment as prevention
Journal Article
Forrest, Jamie I;Rayner, Craig R;Park, Jay J H;Mills, Edward J
10.1007/s40121-020-00349-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Early Treatment of COVID-19 Disease: A Missed Opportunity. [Abstract]: Antivirals have demonstrated efficacy in treating other infectious diseases in early stages of disease, reducing morbidity, mortality, and the likelihood of onward transmission. At the time of writing, more than 1900 clinical trials are reg...
32,443,430
Int J Environ Res Public Health
How to Influence Rural Tourism Intention by Risk Knowledge during COVID-19 Containment in China: Mediating Role of Risk Perception and Attitude.
With both cost and safety taken into account in the context of the life-threatening COVID-19 pandemic globally, rural tourism is expected to be the top choice for Chinese residents for relaxation and enhancing parent-child relationships. In this paper, a structural equation (SEM) model was proposed to compare risk know...
knowledge-attitude-behavior (kab);risk aversion attitude;risk knowledge;rural tourism;tourism risk perception
Journal Article;Research Support, Non-U.S. Gov't
Zhu, Hui;Deng, Fumin
10.3390/ijerph17103514
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: How to Influence Rural Tourism Intention by Risk Knowledge during COVID-19 Containment in China: Mediating Role of Risk Perception and Attitude. [Abstract]: With both cost and safety taken into account in the context of the life-threatening COVID-19 pandemic globally, rural tourism is expected to be the top ch...
32,653,736
Med Hypotheses
Surfactant-based prophylaxis and therapy against COVID-19: A possibility.
Hand hygiene by washing with soap and water is recommended for the prevention of COVID-19 spread. Soaps and detergents are explained to act by damaging viral spike glycoproteins (peplomers) or by washing out the virus through entrapment in the micelles. Technically, soaps come under a functional category of molecules k...
covid-19;peplomer;sars-cov-2;spike glycoprotein;surfactants
Journal Article
Pramod, K;Kotta, Sabna;Jijith, U S;Aravind, A;Abu Tahir, M;Manju, C S;Gangadharappa, H V
10.1016/j.mehy.2020.110081
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Surfactant-based prophylaxis and therapy against COVID-19: A possibility. [Abstract]: Hand hygiene by washing with soap and water is recommended for the prevention of COVID-19 spread. Soaps and detergents are explained to act by damaging viral spike glycoproteins (peplomers) or by washing out the virus through...
33,052,276
Cureus
Bilateral Hemopneumothorax in COVID-19.
A 50-year-old previously healthy male presented with fever and cough for seven days, positive for COVID-19, and was admitted to Hazm Meberik General Hospital and treated as a case of severe COVID-19 pneumonia. After improvement, he was transferred to a quarantine facility, and he later developed bilateral hemopneumotho...
covid 19;pneumothorax
Case Reports
Salah, Omer;Faisal, Mohannad;Alshahwani, Israa;Elhiday, Abdelhaleem
10.7759/cureus.10314
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Bilateral Hemopneumothorax in COVID-19. [Abstract]: A 50-year-old previously healthy male presented with fever and cough for seven days, positive for COVID-19, and was admitted to Hazm Meberik General Hospital and treated as a case of severe COVID-19 pneumonia. After improvement, he was transferred to a quaran...
32,714,873
Front Oncol
Cancer Care During COVID-19 Era: The Quality of Life of Patients With Thyroid Malignancies.
Background: The Covid-19 pandemic's potential psychological impact has been widely discussed on the basis of expert opinion and previous experience with emergencies of this type. We conducted a survey of cancer patients to explore more objectively the outbreak's impact on their emotional well-being and quality of life....
covid-19;cancer care;emotional outbreak;outcomes;quality of life
Journal Article
Falcone, Rosa;Grani, Giorgio;Ramundo, Valeria;Melcarne, Rossella;Giacomelli, Laura;Filetti, Sebastiano;Durante, Cosimo
10.3389/fonc.2020.01128
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cancer Care During COVID-19 Era: The Quality of Life of Patients With Thyroid Malignancies. [Abstract]: Background: The Covid-19 pandemic's potential psychological impact has been widely discussed on the basis of expert opinion and previous experience with emergencies of this type. We conducted a survey of can...
32,818,434
Lancet Infect Dis
COVID-19 and multisystem inflammatory syndrome in children and adolescents.
As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from Europe, North America, Asia, and Latin America describing children and adolescents with COVID-19-associated multisystem inflammatory conditions. However, the association between multisystem inflamma...
Journal Article;Review
Jiang, Li;Tang, Kun;Levin, Mike;Irfan, Omar;Morris, Shaun K;Wilson, Karen;Klein, Jonathan D;Bhutta, Zulfiqar A
10.1016/S1473-3099(20)30651-4
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 and multisystem inflammatory syndrome in children and adolescents. [Abstract]: As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from Europe, North America, Asia, and Latin America describing children and adolescents with COVID-19-asso...
32,850,149
Crit Care Res Pract
The Development of Critical Care Medicine in China: From SARS to COVID-19 Pandemic.
Background: Critical care medicine is a branch of medical science that deals with the characteristics and regularity of life-threatening processes initiated by any injury or disease and, accordingly, relevant treatment for patients with critical illness. Conceptions of critical care medicine in China stemmed in the ear...
Journal Article;Review
Yin, Haiyan;Wang, Shan;Zhu, Youfeng;Zhang, Rui;Ye, Xiaoling;Wei, Jianrui;Hou, Peter C
10.1155/2020/3956732
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Development of Critical Care Medicine in China: From SARS to COVID-19 Pandemic. [Abstract]: Background: Critical care medicine is a branch of medical science that deals with the characteristics and regularity of life-threatening processes initiated by any injury or disease and, accordingly, relevant treatm...
32,164,401
Zhonghua Liu Xing Bing Xue Za Zhi
[COVID-19 pandemic: global epidemiological trends and China's subsequent preparedness and responses].
The outbreak of COVID-19 has spread quickly across 114 countries/territories/areas in six continents worldwide and has been announced as a pandemic by WHO. This study analyzed global COVID-19 epidemiological trends, examined impact of the pandemic on global health security, diplomacy, and social environment in China, a...
covid-19;china's preparedness and responses;pandemic
Journal Article
Guo, Y;Huang, Y M;Huang, J;Jin, Y Z;Jiang, W;Liu, P L;Liu, F J;Ma, J X;Ma, J Y;Wang, Y;Xie, Z;Yin, H;Zhao, C S;Zhou, S D;Zhang, J;Zheng, Z J
10.3760/cma.j.cn112338-20200301-00222
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19 pandemic: global epidemiological trends and China's subsequent preparedness and responses]. [Abstract]: The outbreak of COVID-19 has spread quickly across 114 countries/territories/areas in six continents worldwide and has been announced as a pandemic by WHO. This study analyzed global COVID-19 epide...
33,014,317
Avicenna J Med Biotechnol
Effective Anti-SARS-CoV-2 RNA Dependent RNA Polymerase Drugs Based on Docking Methods: The Case of Milbemycin, Ivermectin, and Baloxavir Marboxil.
Background: Severe Acute Respiratory Syndrome-coronavirus 2 (SARS-CoV-2) is a new virus with a global pandemic. Yet, no vaccine or efficient treatments are found against the disease. The viral RNA dependent RNA Polymerase (RdRP) is a suitable target for developing antiviral agents. SARS-CoV-2 RdRP was employed to test ...
baloxavir;covid-19;ivermectin;tadalafil
Journal Article
Daghir Janabi, Ali Hassan
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Effective Anti-SARS-CoV-2 RNA Dependent RNA Polymerase Drugs Based on Docking Methods: The Case of Milbemycin, Ivermectin, and Baloxavir Marboxil. [Abstract]: Background: Severe Acute Respiratory Syndrome-coronavirus 2 (SARS-CoV-2) is a new virus with a global pandemic. Yet, no vaccine or efficient treatments ...
32,410,141
Mol Biol Rep
Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19.
The ACE2 gene is a receptor of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) for COVID-19 (coronavirus disease 2019). To analyze the expression profiles and clinical significances for this gene in humans, RNA-seq data representing 27 different tissues were analyzed using NCBI; total RNA was extracted fro...
ace2 gene;covid-19;cancer;immunohistochemistry (ihc);rna-sequencing;sars-cov-2;testis
Journal Article
Fu, Jiewen;Zhou, Baixu;Zhang, Lianmei;Balaji, Kyathegowdanadoddi Srinivasa;Wei, Chunli;Liu, Xiaoyan;Chen, Hanchun;Peng, Jiangzhou;Fu, Junjiang
10.1007/s11033-020-05478-4
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19. [Abstract]: The ACE2 gene is a receptor of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) for COVID-19 (coronavirus disease 2019). To analyze the expression profiles and clinical si...
32,632,667
J Clin Monit Comput
First, do no harm: bilateral radial artery occlusion in a COVID-19 patient.
OBJECTIVE: Objective of this case report is to draw attention to a less known thrombotic complication associated with COVID-19, i.e., thrombosis of both radial arteries, with possible (long-term) consequences. THE CASE: In our COVID-19 ICU a 49-year-old male patient was admitted, with past medical history of obesity, s...
artery;covid-19;occlusion;radial;thrombosis
Letter
Bouwhuis, Anne;Schober, Patrick;Heunks, Leo M A;Schwarte, Lothar A
10.1007/s10877-020-00555-2
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: First, do no harm: bilateral radial artery occlusion in a COVID-19 patient. [Abstract]: OBJECTIVE: Objective of this case report is to draw attention to a less known thrombotic complication associated with COVID-19, i.e., thrombosis of both radial arteries, with possible (long-term) consequences. THE CASE: In ...
32,933,150
Viruses
Coronavirus Infections in Companion Animals: Virology, Epidemiology, Clinical and Pathologic Features.
Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The host range and tissue tropism are largely determined by the coronaviral spike protein, which initiates cellular infection by...
covid-19;sars virus;canine;coronavirus;feline infectious peritonitis;ferrets;spike glycoproteins;zoonoses
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Haake, Christine;Cook, Sarah;Pusterla, Nicola;Murphy, Brian
10.3390/v12091023
[ 0, 1, 0, 1, 1, 0, 0 ]
[Title]: Coronavirus Infections in Companion Animals: Virology, Epidemiology, Clinical and Pathologic Features. [Abstract]: Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The ...
33,067,361
Br J Ophthalmol
Retinal findings in hospitalised patients with severe COVID-19.
AIM: To identify retinal findings using dilated eye examination, which are possibly related to SARS-CoV-2 infection in hospitalised patients with confirmed severe COVID-19. METHODS: In this cross-sectional study, hospitalised patients with confirmed severe COVID-19 in a single referral centre for the treatment of COVID...
imaging;infection;retina
Journal Article
Pereira, Leonardo Amarante;Soares, Larissa Caroline Mansano;Nascimento, Priscila Alves;Cirillo, Luciano Rabello Netto;Sakuma, Hebert Toshiaki;Veiga, Glaucia Luciano da;Fonseca, Fernando Luiz Afonso;Lima, Vagner Loduca;Abucham-Neto, Julio Zaki
10.1136/bjophthalmol-2020-317576
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Retinal findings in hospitalised patients with severe COVID-19. [Abstract]: AIM: To identify retinal findings using dilated eye examination, which are possibly related to SARS-CoV-2 infection in hospitalised patients with confirmed severe COVID-19. METHODS: In this cross-sectional study, hospitalised patients ...
33,026,669
J Med Virol
Minimize glycemic fluctuation decrease the risk of severe illness and death in patients with COVID-19.
The recent coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been spreading rapidly throughout the continents. The insights in how this viral disease affects general population is thus urgently needed. Diabetes mellitus is one of the leading threats for mor...
coronavirus < virus classification;sars coronavirus < virus classification;social networks < biostatistics & bioinformatics
Letter
Leng, Yan;Chen, Ming;Dai, Mengyuan;Wu, Yang;Lei, Shao-Qing;Yan, Kuo;Shao, Ning-Yi;Xia, Zhongyuan;Liu, Miao
10.1002/jmv.26584
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Minimize glycemic fluctuation decrease the risk of severe illness and death in patients with COVID-19. [Abstract]: The recent coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been spreading rapidly throughout the continents. The insights in how th...