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32,525,485
JMIR Ment Health
Pediatric Telebehavioral Health: A Transformational Shift in Care Delivery in the Era of COVID-19.
The use of telebehavioral health has been expanding in the past decade to improve access to psychiatric care and address critical shortages in the psychiatric workforce. The coronavirus (COVID-19) pandemic forced a sudden shift from traditional in-person visits to alternative modalities. There are key factors associate...
covid-19;child and adolescent psychiatry;telebehavioral health;telepsychiatry
Journal Article
Ramtekkar, Ujjwal;Bridge, Jeffrey A;Thomas, Glenn;Butter, Eric;Reese, Jennifer;Logan, Erica;Lin, Simon;Axelson, David
10.2196/20157
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pediatric Telebehavioral Health: A Transformational Shift in Care Delivery in the Era of COVID-19. [Abstract]: The use of telebehavioral health has been expanding in the past decade to improve access to psychiatric care and address critical shortages in the psychiatric workforce. The coronavirus (COVID-19) pan...
32,363,205
ERJ Open Res
Epidemiological features and medical care-seeking process of patients with COVID-19 in Wuhan, China.
Background: We aimed to investigate the epidemiological and clinical features, and medical care-seeking process of patients with the 2019 coronavirus disease (COVID-19) in Wuhan, China, to provide useful information to contain COVID-19 in other places with similar outbreaks of the virus. Methods: We collected epidemiol...
Journal Article
Hua, Jing;Chen, Rongzhang;Zhao, Liming;Wu, Xiaodong;Guo, Qian;He, Chunfeng;Li, Tian;Ren, Xiaoyu;Liu, Zhongmin;Li, Qiang;Wang, Feilong
10.1183/23120541.00142-2020
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Epidemiological features and medical care-seeking process of patients with COVID-19 in Wuhan, China. [Abstract]: Background: We aimed to investigate the epidemiological and clinical features, and medical care-seeking process of patients with the 2019 coronavirus disease (COVID-19) in Wuhan, China, to provide u...
32,516,161
Eur J Emerg Med
COVID-19 epidemic in the Seine-Saint-Denis Department of Greater Paris: one month and three waves for a tsunami.
INTRODUCTION: Worldwide, the COVID-19 epidemic has put health systems to the test. The excess mortality is partly due to the influx of patients requiring hospitalization and intensive care. We propose that the chronology of epidemic spread gives a window of time in which hospitals can act to prevent reaching capacity. ...
Journal Article
Lapostolle, Frederic;Goix, Laurent;Vianu, Isabelle;Chanzy, Erick;De Stefano, Carla;Gorlicki, Judith;Petrovic, Tomislav;Adnet, Frederic
10.1097/MEJ.0000000000000723
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 epidemic in the Seine-Saint-Denis Department of Greater Paris: one month and three waves for a tsunami. [Abstract]: INTRODUCTION: Worldwide, the COVID-19 epidemic has put health systems to the test. The excess mortality is partly due to the influx of patients requiring hospitalization and intensive ca...
32,568,413
J Med Virol
Diagnostic efficacy of anti-SARS-CoV-2 IgG/IgM test for COVID-19: A meta-analysis.
The serological testing of anti-SARS-CoV-2 immunoglobulin G (IgG) and/or IgM is widely used in the diagnosis of COVID-19. However, its diagnostic efficacy remains unclear. In this study, we searched for diagnostic studies from the Web of Science, PubMed, Embase, CNKI, and Wanfang databases to calculate the pooled diagn...
covid-2019;sars-cov-2;antibody;diagnostic efficacy
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't
Zhang, Zu-Li;Hou, Yu-Lei;Li, De-Tao;Li, Feng-Zeng
10.1002/jmv.26211
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnostic efficacy of anti-SARS-CoV-2 IgG/IgM test for COVID-19: A meta-analysis. [Abstract]: The serological testing of anti-SARS-CoV-2 immunoglobulin G (IgG) and/or IgM is widely used in the diagnosis of COVID-19. However, its diagnostic efficacy remains unclear. In this study, we searched for diagnostic st...
32,916,352
World Neurosurg
Deployment of Neurosurgeons at the Warfront Against Coronavirus Disease of 2019 (COVID-19).
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has taken the world by storm, especially the health care system. Medical practitioners of all specialties are being assigned to treat patients of COVID-19. In this article, two authors (T.V. and N.G.) from the Department of Neurosurgery who were deployed in t...
covid-19 testing;coronavirus disease of 2019 (covid-19);neurosurgeons;pandemic
Journal Article;Observational Study
Venkataram, Tejas;Goyal, Nishant;Kalita, Deepjyoti;Bahurupi, Yogesh;Gangotri;Sadhasivam, Saravanan;Sharma, Suresh K
10.1016/j.wneu.2020.09.009
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Deployment of Neurosurgeons at the Warfront Against Coronavirus Disease of 2019 (COVID-19). [Abstract]: BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has taken the world by storm, especially the health care system. Medical practitioners of all specialties are being assigned to treat patients of ...
32,100,876
J Med Virol
Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection.
OBJECTIVE: This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients. METHODS: A prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital ...
coronavirus;horizontal transmission;infection
Journal Article
Xia, Jianhua;Tong, Jianping;Liu, Mengyun;Shen, Ye;Guo, Dongyu
10.1002/jmv.25725
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. [Abstract]: OBJECTIVE: This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients. METHODS: A prospective interventional case series study...
32,173,256
Trends Immunol
SARS Coronavirus Redux.
As an atypical pneumonia began to appear in December 2019, Zhou et al. worked with remarkable speed to identify the associated virus, determine its relationship to animal viruses, and evaluate factors conferring infection susceptibility and resistance. These foundational results are being advanced to control the curren...
Journal Article;Research Support, N.I.H., Extramural;Comment
Qing, Enya;Gallagher, Tom
10.1016/j.it.2020.02.007
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS Coronavirus Redux. [Abstract]: As an atypical pneumonia began to appear in December 2019, Zhou et al. worked with remarkable speed to identify the associated virus, determine its relationship to animal viruses, and evaluate factors conferring infection susceptibility and resistance. These foundational res...
32,725,597
Infection
Pulmonary function in patients surviving to COVID-19 pneumonia.
PURPOSE: The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. METHODS: Our case series consisted of 13 patients with COVID-19 pneumonia. RESULTS: At the time of clinical recovery, FEV1 (2.07 +/- 0.72 L) and FVC ...
covid-19;pneumonia;spirometry
Case Reports;Journal Article
Fumagalli, Alessia;Misuraca, Clementina;Bianchi, Achille;Borsa, Noemi;Limonta, Simone;Maggiolini, Sveva;Bonardi, Daniela Rita;Corsonello, Andrea;Di Rosa, Mirko;Soraci, Luca;Lattanzio, Fabrizia;Colombo, Daniele
10.1007/s15010-020-01474-9
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Pulmonary function in patients surviving to COVID-19 pneumonia. [Abstract]: PURPOSE: The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. METHODS: Our case series consisted of 13 patients with COVID-19 ...
32,405,152
Am J Orthod Dentofacial Orthop
Precautions and recommendations for orthodontic settings during the COVID-19 outbreak: A review.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). It emerged as a global pandemic in early 2020, affecting more than 200 countries and territories. The infection is highly contagious, with disease transmission reported from as...
Journal Article;Review
Turkistani, Khadijah A
10.1016/j.ajodo.2020.04.016
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Precautions and recommendations for orthodontic settings during the COVID-19 outbreak: A review. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). It emerged as a global pandemic in early 2020, affecting m...
32,908,072
Drug Discov Ther
Review of current clinical management guidelines for COVID-19 with special reference to India.
The healthcare sector has been overwhelmed by the global rise in the number of COVID-19 cases. The primary care physicians at the forefront of this pandemic are being provided with multiple guidelines (state, national, international). The aim of this review was to examine the existing guidelines for congruence and crit...
coronavirus disease 19;convalescent plasma;dexamethasone;hydroxychloroquine;remdesivir;tocilizumab
Journal Article;Review
Kumar, Rohit;Vinod, Kutty Sharada;Mittal, Ankit;Adhikari, Shreya Das;Gupta, Nitin
10.5582/ddt.2020.03059
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Review of current clinical management guidelines for COVID-19 with special reference to India. [Abstract]: The healthcare sector has been overwhelmed by the global rise in the number of COVID-19 cases. The primary care physicians at the forefront of this pandemic are being provided with multiple guidelines (st...
32,497,810
Int J Infect Dis
Human coronavirus data from four clinical trials of masks and respirators.
There are few published data on the efficacy of masks or respirators against coronavirus infections. This is an important research question to inform the response to the COVID-19 epidemic. The transmission modes of human coronaviruses are similar, thought to be by droplet, contact, and sometimes airborne routes. There ...
Journal Article;Review
MacIntyre, C Raina;Chughtai, Abrar A;Seale, Holly;Dwyer, Dominic E;Quanyi, Wang
10.1016/j.ijid.2020.05.092
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Human coronavirus data from four clinical trials of masks and respirators. [Abstract]: There are few published data on the efficacy of masks or respirators against coronavirus infections. This is an important research question to inform the response to the COVID-19 epidemic. The transmission modes of human cor...
32,755,456
Stroke
Cerebral Microbleeds and Leukoencephalopathy in Critically Ill Patients With COVID-19.
BACKGROUND AND PURPOSE: We conducted this study to investigate the prevalence and distribution of cerebral microbleeds and leukoencephalopathy in hospitalized patients with coronavirus disease 2019 (COVID-19) and correlate with clinical, laboratory, and functional outcomes. METHODS: We performed a retrospective chart r...
covid-19;coronavirus;critical illness;leukoencephalopathy;microbleeds
Journal Article
Agarwal, Shashank;Jain, Rajan;Dogra, Siddhant;Krieger, Penina;Lewis, Ariane;Nguyen, Vinh;Melmed, Kara;Galetta, Steven
10.1161/STROKEAHA.120.030940
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cerebral Microbleeds and Leukoencephalopathy in Critically Ill Patients With COVID-19. [Abstract]: BACKGROUND AND PURPOSE: We conducted this study to investigate the prevalence and distribution of cerebral microbleeds and leukoencephalopathy in hospitalized patients with coronavirus disease 2019 (COVID-19) and...
32,298,139
Arch Pathol Lab Med
Geospatial Hotspots Need Point-of-Care Strategies to Stop Highly Infectious Outbreaks.
CONTEXT.-: Point-of-care testing (POCT), diagnostic testing at or near the site of patient care, is inherently spatial, that is, performed at points of need, and also intrinsically temporal, because it produces fast actionable results. Outbreaks generate geospatial "hotspots." POC strategies help control hotspots, dete...
Journal Article;Review
Kost, Gerald J
10.5858/arpa.2020-0172-RA
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Geospatial Hotspots Need Point-of-Care Strategies to Stop Highly Infectious Outbreaks. [Abstract]: CONTEXT.-: Point-of-care testing (POCT), diagnostic testing at or near the site of patient care, is inherently spatial, that is, performed at points of need, and also intrinsically temporal, because it produces f...
32,895,640
SN Compr Clin Med
COVID-19 and Multiple Sclerosis: Predisposition and Precautions in Treatment.
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to Coronavirus disease 2019 (COVID-19), is not always confined to the respiratory tract, while patients with can develop neurological manifestations. The patients with multiple sclerosis (MS) pose challenges in this pandemic situation,...
covid-19;multiple sclerosis;nervous system;neurological symptoms;sars-cov-2
Journal Article;Review
Sadeghmousavi, Shaghayegh;Rezaei, Nima
10.1007/s42399-020-00504-9
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 and Multiple Sclerosis: Predisposition and Precautions in Treatment. [Abstract]: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to Coronavirus disease 2019 (COVID-19), is not always confined to the respiratory tract, while patients with can develop neurological ma...
32,872,337
Healthcare (Basel)
The First 100 Days: Establishment and Effectiveness of Campus Protection Measures at a College during the COVID-19 Pandemic.
To prevent transmission of the coronavirus, we established the campus protection measures for coronavirus disease 2019 (COVID-19) (CPMCV-19) and analyzed the effectiveness and cost in practice. This project was set in Taiwan. We organized an anti-epidemic task force team from multidisciplinary co-workers to establish t...
covid-19;campus protection measures;college;coronavirus;effectiveness;pandemic
Journal Article
Chang, Tsan-Chang;Lin, Mei-Ying;Huang, Jui-Chi;Yen, Cheng-Tung;Li, Ching-Hui;Jan, Woan-Ching;Huang, Huei-Ying;Liu, Chien-Liang;Chen, Yu-Jen
10.3390/healthcare8030308
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The First 100 Days: Establishment and Effectiveness of Campus Protection Measures at a College during the COVID-19 Pandemic. [Abstract]: To prevent transmission of the coronavirus, we established the campus protection measures for coronavirus disease 2019 (COVID-19) (CPMCV-19) and analyzed the effectiveness an...
32,411,652
Front Public Health
Gender Differences in Patients With COVID-19: Focus on Severity and Mortality.
Objective: The recent outbreak of Novel Coronavirus Disease (COVID-19) is reminiscent of the SARS outbreak in 2003. We aim to compare the severity and mortality between male and female patients with COVID-19 or SARS. Study Design and Setting: We extracted the data from: (1) a case series of 43 hospitalized patients we ...
covid-19;sars;sars-cov-2;female;gender;male;morbidity;mortality
Journal Article;Research Support, Non-U.S. Gov't
Jin, Jian-Min;Bai, Peng;He, Wei;Wu, Fei;Liu, Xiao-Fang;Han, De-Min;Liu, Shi;Yang, Jin-Kui
10.3389/fpubh.2020.00152
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Gender Differences in Patients With COVID-19: Focus on Severity and Mortality. [Abstract]: Objective: The recent outbreak of Novel Coronavirus Disease (COVID-19) is reminiscent of the SARS outbreak in 2003. We aim to compare the severity and mortality between male and female patients with COVID-19 or SARS. Stu...
32,537,527
Infect Dis Model
A novel IDEA: The impact of serial interval on a modified-Incidence Decay and Exponential Adjustment (m-IDEA) model for projections of daily COVID-19 cases.
The SARS-CoV-2 virus causes the disease COVID-19, and has caused high morbidity and mortality worldwide. Empirical models are useful tools to predict future trends of disease progression such as COVID-19 over the near-term. A modified Incidence Decay and Exponential Adjustment (m-IDEA) model was developed to predict th...
covid-19;communicable diseases/epidemiology;forecasting/methods;models;sars coronavirus-2;statistical
Journal Article
Smith, Ben A
10.1016/j.idm.2020.05.003
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A novel IDEA: The impact of serial interval on a modified-Incidence Decay and Exponential Adjustment (m-IDEA) model for projections of daily COVID-19 cases. [Abstract]: The SARS-CoV-2 virus causes the disease COVID-19, and has caused high morbidity and mortality worldwide. Empirical models are useful tools to ...
32,107,909
Zhonghua Wai Ke Za Zhi
[Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease].
Objective: To explore the proper protective measures for pancreatic diseases treatment during the outbreak of 2019 coronavirus disease(COVID-19). Methods: Clinical data of four cases of patients that suffered COVID-19 from February 2(nd) to February 9(th), 2020 at Department of Pancreatic Surgery, Union Hospital, Tongj...
2019 coronavirus disease;coronavirus infections;nosocomial infection;novel coronavirus pneumonia;pancreatic disease;prevention of infection
Case Reports;Journal Article
Gou, S M;Yin, T;Xiong, J X;Peng, T;Li, Y;Wu, H S
10.3760/cma.j.cn112139-20200224-00123
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Treatment of pancreatic diseases and prevention of infection during outbreak of 2019 coronavirus disease]. [Abstract]: Objective: To explore the proper protective measures for pancreatic diseases treatment during the outbreak of 2019 coronavirus disease(COVID-19). Methods: Clinical data of four cases of patie...
32,949,175
J Med Virol
Multiple Organ Injury on Admission Predicts In-Hospital Mortality in Patients with COVID -19.
BACKGROUND: Multiorgan injury has been implicated in patients with coronavirus disease 2019 (COVID-19). We aim to assess the impact of organ injury (OI) on prognosis according to the number of affected organs at admission. METHODS: This is a retrospective cohort study of patients with confirmed COVID-19 in Wuhan Third ...
covid-19;mortality;organ injury;risk factor;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't
Yan, He;Lu, Shanshan;Chen, Liangpei;Wang, Yufang;Liu, Qiaomei;Li, Dongsheng;Yan, Xisheng;Yan, Jie
10.1002/jmv.26534
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Multiple Organ Injury on Admission Predicts In-Hospital Mortality in Patients with COVID -19. [Abstract]: BACKGROUND: Multiorgan injury has been implicated in patients with coronavirus disease 2019 (COVID-19). We aim to assess the impact of organ injury (OI) on prognosis according to the number of affected org...
32,953,249
Comput Mol Biosci
Similarity Studies of Corona Viruses through Chaos Game Representation.
The novel coronavirus (SARS-COV-2) is generally referred to as Covid-19 virus has spread to 213 countries with nearly 7 million confirmed cases and nearly 400,000 deaths. Such major outbreaks demand classification and origin of the virus genomic sequence, for planning, containment, and treatment. Motivated by the above...
chaos game representation;covid-19;deoxyribonucleic acid;phylogenetic analysis;shannon entropy
Journal Article
Sengupta, Dipendra C;Hill, Matthew D;Benton, Kevin R;Banerjee, Hirendra N
10.4236/cmb.2020.103004
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Similarity Studies of Corona Viruses through Chaos Game Representation. [Abstract]: The novel coronavirus (SARS-COV-2) is generally referred to as Covid-19 virus has spread to 213 countries with nearly 7 million confirmed cases and nearly 400,000 deaths. Such major outbreaks demand classification and origin of...
32,790,253
Vopr Pitan
[COVID-19: new challenges for medical science and practical health].
Currently, due to the wide spread of the new coronavirus infection COVID-19 and the need for anti-epidemic measures, medical science should integrate all efforts to ensure, on the one hand, at the global level - the fight against the spread of infection, on the other hand, at the individual level - increasing the adapt...
covid-19;coronavirus;food safety;optimal nutrition;reprofiling
Journal Article
Tutelyan, V A;Nikityuk, D B;Burlyaeva, E A;Khotimchenko, S A;Baturin, A K;Starodubova, A V;Kambarov, A O;Sheveleva, S A;Zhilinskaya, N V
10.24411/0042-8833-2020-10024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19: new challenges for medical science and practical health]. [Abstract]: Currently, due to the wide spread of the new coronavirus infection COVID-19 and the need for anti-epidemic measures, medical science should integrate all efforts to ensure, on the one hand, at the global level - the fight against ...
32,451,906
Ophthalmol Ther
Video Conferencing in the Intravitreal Injection Clinic in Response to the COVID-19 Pandemic.
PURPOSE: To share a useful intervention to minimize risk of COVID-19 infection to both healthcare workers and patients in the eye clinic. METHODS: We present our experience of virtual, within-clinic remote visual acuity assessment to reduce the risk of infection with COVID-19. RESULTS: Along with standard recommendatio...
covid-19;tele-ophthalmology;visual acuity
Journal Article
Saedon, Habiba;Gould, Gemma;Begum, Minara;Aslam, Tariq M
10.1007/s40123-020-00262-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Video Conferencing in the Intravitreal Injection Clinic in Response to the COVID-19 Pandemic. [Abstract]: PURPOSE: To share a useful intervention to minimize risk of COVID-19 infection to both healthcare workers and patients in the eye clinic. METHODS: We present our experience of virtual, within-clinic remote...
32,861,215
J Gerontol B Psychol Sci Soc Sci
Nursing Home Social Workers Perceptions of Preparedness and Coping for COVID-19.
OBJECTIVES: Social work has a long history of responding to the needs of vulnerable populations during times of crisis and disaster. Social workers are working at the front lines responding to the current COVID-19 pandemic in a variety of health care practice settings, including nursing homes, however it is unclear how...
covid-19;health care;long-term care;social workers
Journal Article
Miller, Vivian J;Fields, Noelle L;Anderson, Keith A;Kusmaul, Nancy;Maxwell, Christy
10.1093/geronb/gbaa143
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Nursing Home Social Workers Perceptions of Preparedness and Coping for COVID-19. [Abstract]: OBJECTIVES: Social work has a long history of responding to the needs of vulnerable populations during times of crisis and disaster. Social workers are working at the front lines responding to the current COVID-19 pand...
32,434,946
Science
SARS-CoV-2 infection protects against rechallenge in rhesus macaques.
An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies aimed at ending the global coronavirus disease 2019 (COVID-19) pandemic. A key unanswered question is whether infection with SARS-CoV-2 results in protective immun...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Chandrashekar, Abishek;Liu, Jinyan;Martinot, Amanda J;McMahan, Katherine;Mercado, Noe B;Peter, Lauren;Tostanoski, Lisa H;Yu, Jingyou;Maliga, Zoltan;Nekorchuk, Michael;Busman-Sahay, Kathleen;Terry, Margaret;Wrijil, Linda M;Ducat, Sarah;Martinez, David R;Atyeo, Caroline;Fischinger, Stephanie;Burke, John S;Slein, Matthew ...
10.1126/science.abc4776
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection protects against rechallenge in rhesus macaques. [Abstract]: An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies aimed at ending the global coronavirus disease 2019 (COVID-19) pandemic....
32,669,878
Clin Epidemiol
Trend Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission in 16 Cities of Hubei Province, China.
Objective: A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detected by researchers from a patient in Wuhan, Hubei province, China, in December 2019, and broke out in January 2020. Then, the pandemic was detected in countries around the world. Therefore, precise estimates of its current and future tre...
china;sars-cov-2;wuhan;cities;death;trends
Journal Article
Fawad, Muhammad;Mubarik, Sumaira;Malik, Saima Shakil;Hao, Yangyang;Yu, Chuanhua;Ren, Jingli
10.2147/CLEP.S254806
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Trend Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission in 16 Cities of Hubei Province, China. [Abstract]: Objective: A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detected by researchers from a patient in Wuhan, Hubei province, China, in December 2019, ...
32,823,148
Mult Scler Relat Disord
Mild or no COVID-19 symptoms in cladribine-treated multiple sclerosis: Two cases and implications for clinical practice.
BACKGROUND: The use of disease-modifying therapies (DMTs) in multiple sclerosis (MS) could affect COVID-19 outcomes by modulating the immune response, which, in turn, might favor viral replication and/or confer protection from COVID-19 induced inflammatory response CASE REPORT: We report on two MS patients treated with...
covid-19;cladribine;lymphocytes;multiple sclerosis
Case Reports;Letter
De Angelis, Marcello;Petracca, Maria;Lanzillo, Roberta;Brescia Morra, Vincenzo;Moccia, Marcello
10.1016/j.msard.2020.102452
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Mild or no COVID-19 symptoms in cladribine-treated multiple sclerosis: Two cases and implications for clinical practice. [Abstract]: BACKGROUND: The use of disease-modifying therapies (DMTs) in multiple sclerosis (MS) could affect COVID-19 outcomes by modulating the immune response, which, in turn, might favor...
32,883,593
Transfus Apher Sci
SARS-CoV-2 serology and virology trends in donors and recipients of convalescent plasma.
SARS-CoV-2 has infected millions worldwide. The virus is novel, and currently there is no approved treatment. Convalescent plasma may offer a treatment option. We evaluated trends of IgM/IgG antibodies/plasma viral load in donors and recipients of convalescent plasma. 114/139 (82 %) donors had positive IgG antibodies. ...
adults;antigens;blood transfusion;covid-19;covid-19 serotherapy;coronavirus;coronavirus infections;humans;immunoglobulin g;immunoglobulin m;plasma;sars virus;severe acute respiratory syndrome;severe acute respiratory syndrome coronavirus 2;viral;viral load
Clinical Trial, Phase II;Journal Article
Dulipsingh, Latha;Ibrahim, Danyal;Schaefer, Ernst J;Crowell, Rebecca;Diffenderfer, Margaret R;Williams, Kendra;Lima, Colleen;McKenzie, Jessica;Cook, Lisa;Puff, Jennifer;Onoroski, Mary;Wakefield, Dorothy B;Eadie, Reginald J;Kleiboeker, Steven B;Nabors, Patricia;Hussain, Syed A
10.1016/j.transci.2020.102922
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 serology and virology trends in donors and recipients of convalescent plasma. [Abstract]: SARS-CoV-2 has infected millions worldwide. The virus is novel, and currently there is no approved treatment. Convalescent plasma may offer a treatment option. We evaluated trends of IgM/IgG antibodies/plasma v...
32,969,768
Emerg Microbes Infect
Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cells.
Studies on patients with the coronavirus disease-2019 (COVID-19) have implicated that the gastrointestinal (GI) tract is a major site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We established a human GI tract cell line model highly permissive to SARS-CoV-2. These cells, C2BBe1 intestinal...
ace2;covid-19;sars-cov-2;coronavirus;persistent
Journal Article
Lee, Sunhee;Yoon, Gun Young;Myoung, Jinjong;Kim, Seong-Jun;Ahn, Dae-Gyun
10.1080/22221751.2020.1827985
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cells. [Abstract]: Studies on patients with the coronavirus disease-2019 (COVID-19) have implicated that the gastrointestinal (GI) tract is a major site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inf...
33,078,035
Appl Clay Sci
Modeling of the adsorption of a protein-fragment on kaolinite with potential antiviral activity.
This work aimed at studying the potentiality of interactions between kaolinite surfaces and a protein-fragment (350-370 amino acid units) extracted from the glycoprotein E1 in the transmembrane domain (TMD) of hepatitis C virus capsid. A computational work was performed for locating the potential electrostatic interact...
adsorption;glycoprotein e1;hepatitis c virus;hydration;kaolinite;molecular dynamics;transmembrane domain;virus sorption on minerals
Journal Article
Awad, Mahmoud E;Borrego-Sanchez, Ana;Escamilla-Roa, Elizabeth;Hernandez-Laguna, Alfonso;Sainz-Diaz, C Ignacio
10.1016/j.clay.2020.105865
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Modeling of the adsorption of a protein-fragment on kaolinite with potential antiviral activity. [Abstract]: This work aimed at studying the potentiality of interactions between kaolinite surfaces and a protein-fragment (350-370 amino acid units) extracted from the glycoprotein E1 in the transmembrane domain (...
33,040,198
Mol Genet Genomics
SARS-CoV-2 has the advantage of competing the iMet-tRNAs with human hosts to allow efficient translation.
To better understand the interaction between SARS-CoV-2 and human host and find potential ways to block the pandemic, one of the unresolved questions is that how the virus economically utilizes the resources of the hosts. Particularly, the tRNA pool has been adapted to the host genes. If the virus intends to translate ...
methionine (met);sars-cov-2;translation initiation;trna
Journal Article
Wang, Yan;Gai, Yanhong;Li, Yuefan;Li, Chunxiao;Li, Ziliang;Wang, Xuekun
10.1007/s00438-020-01731-4
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 has the advantage of competing the iMet-tRNAs with human hosts to allow efficient translation. [Abstract]: To better understand the interaction between SARS-CoV-2 and human host and find potential ways to block the pandemic, one of the unresolved questions is that how the virus economically utilizes...
32,585,417
Clin Imaging
Bringing radiology to patient's home using mobile equipment: A weapon to fight COVID-19 pandemic.
Because of coronavirus disease 2019 (COVID-19) high contagiousness, it is crucial to identify and promptly isolate COVID-19 patients. In this context, chest imaging examinations, in particular chest x-ray (CXR), can play a pivotal role in different settings, to triage in case of unavailability, delay of or first negati...
covid-19;covid-19 diagnostic testing;infection control;mobile radiography;radiography
Journal Article
Zanardo, Moreno;Schiaffino, Simone;Sardanelli, Francesco
10.1016/j.clinimag.2020.06.031
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Bringing radiology to patient's home using mobile equipment: A weapon to fight COVID-19 pandemic. [Abstract]: Because of coronavirus disease 2019 (COVID-19) high contagiousness, it is crucial to identify and promptly isolate COVID-19 patients. In this context, chest imaging examinations, in particular chest x-...
32,713,715
Acad Radiol
Semiquantitative lung ultrasound scores in the evaluation and follow-up of critically ill patients with COVID-19: a single-center study.
RATIONALE AND OBJECTIVES: Chest CT is not suitable for critically ill patients with COVID-19 and lung ultrasound (LUS) may play an important role for these patients. In this study, we summarized the findings of LUS and explore the value of semiquantitative LUS scores in evaluation and follow-up of COVID-19 pneumonia. M...
covid-19;evaluation;lung ultrasound;pneumonia
Journal Article;Research Support, Non-U.S. Gov't
Deng, Qing;Zhang, Yao;Wang, Hao;Chen, Liao;Yang, Zhaohui;Peng, Zhoufeng;Liu, Ya;Feng, Chuangli;Huang, Xin;Jiang, Nan;Wang, Yijia;Guo, Juan;Sun, Bin;Zhou, Qing
10.1016/j.acra.2020.07.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Semiquantitative lung ultrasound scores in the evaluation and follow-up of critically ill patients with COVID-19: a single-center study. [Abstract]: RATIONALE AND OBJECTIVES: Chest CT is not suitable for critically ill patients with COVID-19 and lung ultrasound (LUS) may play an important role for these patien...
32,717,854
Vaccines (Basel)
Immunogenic SARS-CoV-2 Epitopes: In Silico Study Towards Better Understanding of COVID-19 Disease-Paving the Way for Vaccine Development.
The emergence of the COVID-19 outbreak at the end of 2019, caused by the novel coronavirus SARS-CoV-2, has, to date, led to over 13.6 million infections and nearly 600,000 deaths. Consequently, there is an urgent need to better understand the molecular factors triggering immune defense against the virus and to develop ...
covid-19;hla;mhc class i epitopes;sars-cov;sars-cov-2;antigen presentation;homology modeling;immunoinformatics;in silico analysis;molecular dynamics simulations;structural biology;vaccine development;viral peptides
Journal Article
Ranga, Vipin;Niemela, Erik;Tamirat, Mahlet Z;Eriksson, John E;Airenne, Tomi T;Johnson, Mark S
10.3390/vaccines8030408
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immunogenic SARS-CoV-2 Epitopes: In Silico Study Towards Better Understanding of COVID-19 Disease-Paving the Way for Vaccine Development. [Abstract]: The emergence of the COVID-19 outbreak at the end of 2019, caused by the novel coronavirus SARS-CoV-2, has, to date, led to over 13.6 million infections and near...
32,759,918
MMWR Morb Mortal Wkly Rep
Characteristics and Outcomes of Contacts of COVID-19 Patients Monitored Using an Automated Symptom Monitoring Tool - Maine, May-June 2020.
SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is spread from person to person (1-3). Quarantine of exposed persons (contacts) for 14 days following their exposure reduces transmission (4-7). Contact tracing provides an opportunity to identify contacts, inform them of quarantine recommendations,...
Journal Article
Krueger, Anna;Gunn, Jayleen K L;Watson, Joanna;Smith, Andrew E;Lincoln, Rebecca;Huston, Sara L;Dirlikov, Emilio;Robinson, Sara
10.15585/mmwr.mm6931e2
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Characteristics and Outcomes of Contacts of COVID-19 Patients Monitored Using an Automated Symptom Monitoring Tool - Maine, May-June 2020. [Abstract]: SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is spread from person to person (1-3). Quarantine of exposed persons (contacts) for 14 da...
32,629,642
Medicine (Baltimore)
Acupuncture for breathlessness in COVID-19: A protocol for systematic review and meta-analysis.
BACKGROUND: At present, accumulative attention has been paid to coronavirus disease 2019 (COVID-19) due to its global prevalence. Acupuncture may play a beneficial role in patients with breathlessness in COVID-19. This study is designed to determine the efficacy and safety of acupuncture for breathlessness in COVID-19....
Journal Article
Zhang, Baozhen;Zhang, Kai;Tang, Qilin;Sun, Kaihang;Han, Zhenzhen
10.1097/MD.0000000000020701
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Acupuncture for breathlessness in COVID-19: A protocol for systematic review and meta-analysis. [Abstract]: BACKGROUND: At present, accumulative attention has been paid to coronavirus disease 2019 (COVID-19) due to its global prevalence. Acupuncture may play a beneficial role in patients with breathlessness in...
32,754,609
Front Med (Lausanne)
Immune Thrombocytopenia in a Very Elderly Patient With Covid-19.
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (...
covid-19;corticosteroids;immune thrombocytopenia;intravenous immunoglobulin;very old age
Case Reports
Hindilerden, Fehmi;Yonal-Hindilerden, Ipek;Sevtap, Senoglu;Kart-Yasar, Kadriye
10.3389/fmed.2020.00404
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Immune Thrombocytopenia in a Very Elderly Patient With Covid-19. [Abstract]: Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodefici...
32,850,746
Front Bioeng Biotechnol
Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 2019.
Objectives: Coronavirus disease 2019 (COVID-19) is sweeping the globe and has resulted in infections in millions of people. Patients with COVID-19 face a high fatality risk once symptoms worsen; therefore, early identification of severely ill patients can enable early intervention, prevent disease progression, and help...
covid-19;computed tomography;deep learning;disease severity;multiple instance learning
Journal Article
Xiao, Lu-Shan;Li, Pu;Sun, Fenglong;Zhang, Yanpei;Xu, Chenghai;Zhu, Hongbo;Cai, Feng-Qin;He, Yu-Lin;Zhang, Wen-Feng;Ma, Si-Cong;Hu, Chenyi;Gong, Mengchun;Liu, Li;Shi, Wenzhao;Zhu, Hong
10.3389/fbioe.2020.00898
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 2019. [Abstract]: Objectives: Coronavirus disease 2019 (COVID-19) is sweeping the globe and has resulted in infections in millions of people. Patients with COVID-19...
32,791,258
Am J Infect Control
Direct COVID-19 infection of enterocytes: The role of hypochlorhydria.
COVD-19 disease is characteristically respiratory in nature; however, some patients have gastrointestinal symptoms. These include changes in taste, nausea/vomiting, abdominal pain, and diarrhea. A report has been published of a young patient who repeatedly tested positive in stool samples while nasopharyngeal tests rem...
asymptomatic transmission;fecal-oral transmission;proton pump inhibitors
Journal Article
Dibner, Julia J
10.1016/j.ajic.2020.08.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Direct COVID-19 infection of enterocytes: The role of hypochlorhydria. [Abstract]: COVD-19 disease is characteristically respiratory in nature; however, some patients have gastrointestinal symptoms. These include changes in taste, nausea/vomiting, abdominal pain, and diarrhea. A report has been published of a ...
33,030,102
J Biomol Struct Dyn
Finding potent inhibitors for COVID-19 main protease (M(pro)): an in silico approach using SARS-CoV-3CL protease inhibitors for combating CORONA.
SARS-CoV-2 is liable for the worldwide coronavirus disease (COVID-19) exigency. This pandemic created the need for all viable treatment strategies available in the market. In this scenario, computer-aided drug design techniques can be efficiently applied for the quick identification of promising drug repurposing candid...
covid-19;coronavirus;sars-cov-2;main protease (mpro);molecular dynamics simulation;molecular modeling;virtual screening
Journal Article
Motiwale, Mohit;Yadav, Neetu Singh;Kumar, Sushil;Kushwaha, Tushar;Choudhir, Gourav;Sharma, Supriya;Singour, Pradeep Kumar
10.1080/07391102.2020.1829501
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Finding potent inhibitors for COVID-19 main protease (M(pro)): an in silico approach using SARS-CoV-3CL protease inhibitors for combating CORONA. [Abstract]: SARS-CoV-2 is liable for the worldwide coronavirus disease (COVID-19) exigency. This pandemic created the need for all viable treatment strategies availa...
32,253,888
J Biol Regul Homeost Agents
Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection.
CoV-19/SARS-CoV-2 is a highly pathogenic virus that causes coronavirus-19 disease (COVID-19) an acute respiratory distress syndrome which provokes serious problems for global health. Studies suggest that there are many differences between men and women in the immune response to CoV-19 infection and inflammatory disease...
cov-19;coronavirus 19;gender;immunity cytokine;virus
Editorial
Conti, P;Younes, A
10.23812/Editorial-Conti-3
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection. [Abstract]: CoV-19/SARS-CoV-2 is a highly pathogenic virus that causes coronavirus-19 disease (COVID-19) an acute respiratory distress syndrome which provokes serious problems for global health. Studies suggest tha...
32,290,293
Int J Mol Sci
A Review of SARS-CoV-2 and the Ongoing Clinical Trials.
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, affecting not only the healthcare system, but also the global economy. Although our understanding ...
ace2;covid-19;sars-cov-2;clinical trials;immunotherapy;pneumonia;replicase;vaccine
Journal Article;Review
Tu, Yung-Fang;Chien, Chian-Shiu;Yarmishyn, Aliaksandr A;Lin, Yi-Ying;Luo, Yung-Hung;Lin, Yi-Tsung;Lai, Wei-Yi;Yang, De-Ming;Chou, Shih-Jie;Yang, Yi-Ping;Wang, Mong-Lien;Chiou, Shih-Hwa
10.3390/ijms21072657
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Review of SARS-CoV-2 and the Ongoing Clinical Trials. [Abstract]: The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, affecting not only th...
32,989,072
J Am Board Fam Med
A Practice-Based Research Network (PBRN) Roadmap for Evaluating COVID-19 in Community Health Centers: A Report From the OCHIN PBRN.
BACKGROUND: Primary care practice-based research networks (PBRNs) are critical laboratories for generating evidence from real-world settings, including studying natural experiments. Primary care's response to the novel coronavirus-19 (COVID-19) pandemic is arguably the most impactful natural experiment in our lifetime....
covid-19;community health centers;coronavirus;decision making;delivery of health care;evidence-based medicine;evidence-based practice;implementation science;information dissemination;organizational innovation;pandemics;practice-based research;primary health care
Evaluation Study;Journal Article
DeVoe, Jennifer E;Likumahuwa-Ackman, Sonja M;Angier, Heather E;Huguet, Nathalie;Cohen, Deborah J;Flocke, Susan A;Marino, Miguel;Gold, Rachel
10.3122/jabfm.2020.05.200053
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Practice-Based Research Network (PBRN) Roadmap for Evaluating COVID-19 in Community Health Centers: A Report From the OCHIN PBRN. [Abstract]: BACKGROUND: Primary care practice-based research networks (PBRNs) are critical laboratories for generating evidence from real-world settings, including studying natura...
32,366,611
Pediatrics
Severe Pediatric COVID-19 Presenting With Respiratory Failure and Severe Thrombocytopenia.
The novel severe acute respiratory syndrome coronavirus 2 is a worldwide pandemic. The severe morbidity and mortality associated with coronavirus disease 2019 has mostly affected the elderly or those with underlying medical conditions. We present a case of a 12-year-old girl with no past medical history who presented w...
Case Reports;Journal Article;Research Support, N.I.H., Extramural
Patel, Pratik A;Chandrakasan, Shanmuganathan;Mickells, Geoffrey E;Yildirim, Inci;Kao, Carol M;Bennett, Carolyn M
10.1542/peds.2020-1437
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe Pediatric COVID-19 Presenting With Respiratory Failure and Severe Thrombocytopenia. [Abstract]: The novel severe acute respiratory syndrome coronavirus 2 is a worldwide pandemic. The severe morbidity and mortality associated with coronavirus disease 2019 has mostly affected the elderly or those with und...
32,300,496
Cureus
Coronavirus Disease: A Review of a New Threat to Public Health.
In December 2019, several patients from Wuhan, China were admitted to hospitals with symptoms of pneumonia. As the number of patients presenting with similar symptoms started to rise, the causative agent was eventually isolated from samples. It was initially called the 2019 novel coronavirus (2019-nCoV) and has been re...
coronavirus disease;covid-19;sars-cov-2;severe acute respiratory syndrome coronavirus 2;wuhan
Journal Article;Review
Ramphul, Kamleshun;Mejias, Stephanie G
10.7759/cureus.7276
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease: A Review of a New Threat to Public Health. [Abstract]: In December 2019, several patients from Wuhan, China were admitted to hospitals with symptoms of pneumonia. As the number of patients presenting with similar symptoms started to rise, the causative agent was eventually isolated from sa...
32,807,047
Comb Chem High Throughput Screen
Potential Leads from Liquorice against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies.
AIM AND OBJECTIVE: At present, the world is facing a global pandemic threat of SARS-CoV-2 or COVID-19 and till date, there are no clinically approved vaccines or antiviral drugs available for the treatment of coronavirus infections. Studies conducted in China recommended the use of liquorice (Glycyrrhiza species), an i...
1-methoxyphaseollidin.;covid-19;glyasperin;glycyrrhizic acid;isoliquiritin apioside;liquiritin
Journal Article;Research Support, Non-U.S. Gov't
Sinha, Saurabh K;Prasad, Satyendra K;Islam, Md Ataul;Chaudhary, Sushil K;Singh, Shashikant;Shakya, Anshul
10.2174/1386207323999200817103148
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential Leads from Liquorice against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. [Abstract]: AIM AND OBJECTIVE: At present, the world is facing a global pandemic threat of SARS-CoV-2 or COVID-19 and till date, there are no clinically approved vaccines or antiviral drugs available for...
32,834,586
Chaos Solitons Fractals
A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies.
We employ deep learning to propose an Artificial Neural Network (ANN) based and data stream guided real-time incremental learning algorithm for parameter estimation of a non-intrusive, intelligent, adaptive and online analytical model of Covid-19 disease. Modeling and simulation of such problems pose an additional chal...
covid-19;deep learning;immunization;incremental learning;policy making
Journal Article
Farooq, Junaid;Bazaz, Mohammad Abid
10.1016/j.chaos.2020.110148
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies. [Abstract]: We employ deep learning to propose an Artificial Neural Network (ANN) based and data stream guided real-time incremental learning algorithm for parameter estimation of a non-intrusive, intelligent, adapti...
32,517,835
Infect Control Hosp Epidemiol
Delayed Recognition of Community Transmission of COVID-19 Resulting in Healthcare Worker Infections.
We describe a case of delayed COVID-19 diagnosis due to unrecognized community transmission in Atlanta, Georgia in mid-February 2020. This case resulted in transmission of COVID-19 to three of the four healthcare workers present during a diagnostic bronchoscopy procedure where only procedural masks were worn.
covid-19;coronavirus;sars-cov-2;healthcare-associated
Journal Article
Dantes, Raymund B;Jones, Tait T;Neujahr, David C
10.1017/ice.2020.285
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Delayed Recognition of Community Transmission of COVID-19 Resulting in Healthcare Worker Infections. [Abstract]: We describe a case of delayed COVID-19 diagnosis due to unrecognized community transmission in Atlanta, Georgia in mid-February 2020. This case resulted in transmission of COVID-19 to three of the f...
33,071,103
Am J Emerg Med
The role of Chinese medicine in COVID-19 pneumonia: A systematic review and meta-analysis.
INTRODUCTION: Chinese medicine (CM) has been used to treat Novel Coronavirus 2019 (COVID-19) pneumonia in China. This meta-analysis was conducted to evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia. METHODS: Randomized controlled trials (RCTs) involving CM in the treatment of COVID...
covid-19 pneumonia;chinese medicine;meta-analysis
Journal Article;Meta-Analysis;Research Support, Non-U.S. Gov't;Systematic Review
Sun, Chun-Yang;Sun, Ya-Lei;Li, Xin-Min
10.1016/j.ajem.2020.06.069
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The role of Chinese medicine in COVID-19 pneumonia: A systematic review and meta-analysis. [Abstract]: INTRODUCTION: Chinese medicine (CM) has been used to treat Novel Coronavirus 2019 (COVID-19) pneumonia in China. This meta-analysis was conducted to evaluate the clinical efficacy and safety of CM in the trea...
32,925,136
Work
Rising incidence of musculoskeletal discomfort in the wake of the COVID-19 crisis.
The COVID-19 pandemic has led to the shutdown of much of the world's economic and social operations. Given shutdown of exercise facilities, there has been a sharp uptick in a sedentary lifestyle. As people have lost their normal daily activity patterns, it is reasonable to assume that musculoskeletal pain-related syndr...
covid-19;musculoskeletal discomforts;pain;pandemic
Journal Article
Memari, Amirhossein;Shariat, Ardalan;Anastasio, Albert Thomas
10.3233/WOR-203221
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rising incidence of musculoskeletal discomfort in the wake of the COVID-19 crisis. [Abstract]: The COVID-19 pandemic has led to the shutdown of much of the world's economic and social operations. Given shutdown of exercise facilities, there has been a sharp uptick in a sedentary lifestyle. As people have lost ...
32,733,842
Front Public Health
Progress in the Research and Development of Anti-COVID-19 Drugs.
The outbreaks of COVID-19 due to SARS-CoV-2 has caused serious physical and psychological damage to global human health. COVID-19 spread rapidly around the world in a short time. Confronted with such a highly infectious respiratory disease, the research and development of anti-COVID-19 drugs became an urgent work due t...
covid-19;sars-cov-2;anti-covid-19 drugs;chloroquine;glucocorticoid;lopinavir/ritonavir;plasma therapy;remdesivir
Journal Article;Review
Huang, Lianzhou;Chen, Yuanqiu;Xiao, Ji;Luo, Weisheng;Li, Feng;Wang, Yuan;Wang, Yiliang;Wang, Yifei
10.3389/fpubh.2020.00365
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Progress in the Research and Development of Anti-COVID-19 Drugs. [Abstract]: The outbreaks of COVID-19 due to SARS-CoV-2 has caused serious physical and psychological damage to global human health. COVID-19 spread rapidly around the world in a short time. Confronted with such a highly infectious respiratory di...
32,628,040
Arterioscler Thromb Vasc Biol
Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients.
OBJECTIVE: The objectives were to investigate and compare the risks and incidences of venous thromboembolism (VTE) between the 2 groups of patients with coronavirus disease 2019 (COVID-19) pneumonia and community-acquired pneumonia (CAP). Approach and Results: Medical records of 616 pneumonia patients who were admitted...
critical illness;hospital mortality;incidence;pneumonia;venous thromboembolism
Comparative Study;Journal Article
Mei, Fei;Fan, Jiawei;Yuan, Jinhua;Liang, Zhenzhen;Wang, Kewei;Sun, Jianfeng;Guan, Wenfei;Huang, Mingkui;Li, Yu;Zhang, Wayne W
10.1161/ATVBAHA.120.314779
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients. [Abstract]: OBJECTIVE: The objectives were to investigate and compare the risks and incidences of venous thromboembolism (VTE) between the 2 groups of patients with coronavirus disease 2019 (COVID-1...
32,563,180
J Clin Virol
Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation.
There is an urgent need for reliable high-throughput serological assays for the management of the ongoing COVID-19 pandemic. Preferably, the performance of serological tests for a novel virus should be determined with clinical specimens against a gold standard, i.e. virus neutralisation. We compared the performance of ...
covid-19;iga;igg;neutralisation;sars-cov-2;serology
Comparative Study;Evaluation Study;Journal Article;Research Support, Non-U.S. Gov't
Jaaskelainen, A J;Kuivanen, S;Kekalainen, E;Ahava, M J;Loginov, R;Kallio-Kokko, H;Vapalahti, O;Jarva, H;Kurkela, S;Lappalainen, M
10.1016/j.jcv.2020.104512
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Performance of six SARS-CoV-2 immunoassays in comparison with microneutralisation. [Abstract]: There is an urgent need for reliable high-throughput serological assays for the management of the ongoing COVID-19 pandemic. Preferably, the performance of serological tests for a novel virus should be determined wit...
32,323,016
Surg Endosc
SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic.
The unprecedented pandemic of COVID-19 has impacted many lives and affects the whole healthcare systems globally. In addition to the considerable workload challenges, surgeons are faced with a number of uncertainties regarding their own safety, practice, and overall patient care. This guide has been drafted at short no...
covid-19;laparoscopy;surgery
Journal Article;Practice Guideline
Francis, Nader;Dort, Jonathan;Cho, Eugene;Feldman, Liane;Keller, Deborah;Lim, Rob;Mikami, Dean;Phillips, Edward;Spaniolas, Konstantinos;Tsuda, Shawn;Wasco, Kevin;Arulampalam, Tan;Sheraz, Markar;Morales, Salvador;Pietrabissa, Andrea;Asbun, Horacio;Pryor, Aurora
10.1007/s00464-020-07565-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic. [Abstract]: The unprecedented pandemic of COVID-19 has impacted many lives and affects the whole healthcare systems globally. In addition to the considerable workload challenges, surgeons are faced with a number of uncertai...
32,729,463
Elife
Neuropathogenesis of SARS-CoV-2 infection.
The COVID-19 pandemic caused by the SARS-CoV-2 has recently emerged as a serious jolt to human life and economy. Initial knowledge established pulmonary complications as the chief symptom, however, the neurological aspect of the disease is also becoming increasingly evident. Emerging reports of encephalopathies and sim...
covid-19;sars-cov-2;brain;epidemiology;global health;human;neurological disorder;neuroscience;neurotropic behaviour;stroke
Journal Article;Research Support, Non-U.S. Gov't;Review
Khan, Shumayila;Gomes, James
10.7554/eLife.59136
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Neuropathogenesis of SARS-CoV-2 infection. [Abstract]: The COVID-19 pandemic caused by the SARS-CoV-2 has recently emerged as a serious jolt to human life and economy. Initial knowledge established pulmonary complications as the chief symptom, however, the neurological aspect of the disease is also becoming in...
32,556,323
Phys Ther
Recommendations for Hospital-Based Physical Therapists Managing Patients With COVID-19.
OBJECTIVE: The COVID-19 pandemic is rapidly evolving and has led to increased numbers of hospitalizations worldwide. Hospitalized patients with COVID-19 experience a variety of symptoms, including fever, muscle pain, tiredness, cough, and difficulty breathing. Elderly people and those with underlying health conditions ...
Journal Article
Felten-Barentsz, Karin M;van Oorsouw, Roel;Klooster, Emily;Koenders, Niek;Driehuis, Femke;Hulzebos, Erik H J;van der Schaaf, Marike;Hoogeboom, Thomas J;van der Wees, Philip J
10.1093/ptj/pzaa114
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for Hospital-Based Physical Therapists Managing Patients With COVID-19. [Abstract]: OBJECTIVE: The COVID-19 pandemic is rapidly evolving and has led to increased numbers of hospitalizations worldwide. Hospitalized patients with COVID-19 experience a variety of symptoms, including fever, muscle ...
32,526,092
J Thromb Haemost
Thromboprophylaxis in a patient with COVID-19 and severe hemophilia A on emicizumab prophylaxis.
COVID-19 can be associated with coagulopathy (CAC, COVID-19-associated coagulopathy) with a high prothrombotic risk based on an intense inflammatory response to viral infection leading to immunothrombosis through different procoagulant pathways. Emerging evidence suggests that the use of heparin in these patients could...
covid-19;emicizumab;hemophilia;thromboprophylaxis;thrombosis
Case Reports;Research Support, Non-U.S. Gov't
Rivas-Pollmar, Maria Isabel;Alvarez-Roman, Maria Teresa;Butta-Coll, Nora V;Martin Salces, Monica;Garcia-Barcenilla, Sara;Jimenez-Yuste, Victor
10.1111/jth.14954
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Thromboprophylaxis in a patient with COVID-19 and severe hemophilia A on emicizumab prophylaxis. [Abstract]: COVID-19 can be associated with coagulopathy (CAC, COVID-19-associated coagulopathy) with a high prothrombotic risk based on an intense inflammatory response to viral infection leading to immunothrombos...
32,618,358
Clin Cardiol
ACC.20: Impact of social media at the virtual scientific sessions during the COVID-19 pandemic.
BACKGROUND: The COVID-19 pandemic led to the American College of Cardiology (ACC) Annual Scientific Session 2020 (ACC.20) being held as a virtual event. HYPOTHESIS: Social media activity around a virtual event might be quite different to that of a physical meeting. The goal of this study was to assess impact of ACC.20 ...
acc20;covid-19;virtual acc scientific sessions;impact of social media
Journal Article
Mackenzie, Graham;Gulati, Martha
10.1002/clc.23387
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: ACC.20: Impact of social media at the virtual scientific sessions during the COVID-19 pandemic. [Abstract]: BACKGROUND: The COVID-19 pandemic led to the American College of Cardiology (ACC) Annual Scientific Session 2020 (ACC.20) being held as a virtual event. HYPOTHESIS: Social media activity around a virtual...
32,651,212
Sci Immunol
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19.
Although most SARS-CoV-2-infected individuals experience mild coronavirus disease 2019 (COVID-19), some patients suffer from severe COVID-19, which is accompanied by acute respiratory distress syndrome and systemic inflammation. To identify factors driving severe progression of COVID-19, we performed single-cell RNA-se...
Journal Article
Lee, Jeong Seok;Park, Seongwan;Jeong, Hye Won;Ahn, Jin Young;Choi, Seong Jin;Lee, Hoyoung;Choi, Baekgyu;Nam, Su Kyung;Sa, Moa;Kwon, Ji-Soo;Jeong, Su Jin;Lee, Heung Kyu;Park, Sung Ho;Park, Su-Hyung;Choi, Jun Yong;Kim, Sung-Han;Jung, Inkyung;Shin, Eui-Cheol
10.1126/sciimmunol.abd1554
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19. [Abstract]: Although most SARS-CoV-2-infected individuals experience mild coronavirus disease 2019 (COVID-19), some patients suffer from severe COVID-19, which is accompanied by acute respir...
32,495,913
Eur Rev Med Pharmacol Sci
Severe acute dried gangrene in COVID-19 infection: a case report.
OBJECTIVE: Coronavirus disease 2019 (COVID-19) related coagulopathy may be the first clinical manifestation even in non-vasculopathic patients and is often associated with worse clinical outcomes. CASE PRESENTATION: A 78 years old woman was admitted to the Emergency Unit with respiratory symptoms, confusion and cyanosi...
Case Reports;Journal Article
Novara, E;Molinaro, E;Benedetti, I;Bonometti, R;Lauritano, E C;Boverio, R
10.26355/eurrev_202005_21369
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe acute dried gangrene in COVID-19 infection: a case report. [Abstract]: OBJECTIVE: Coronavirus disease 2019 (COVID-19) related coagulopathy may be the first clinical manifestation even in non-vasculopathic patients and is often associated with worse clinical outcomes. CASE PRESENTATION: A 78 years old wo...
32,980,956
Dig Dis Sci
Hepatic Steatosis Is Associated with Increased Disease Severity and Liver Injury in Coronavirus Disease-19.
BACKGROUND: Coronavirus disease-2019 (COVID-19) is a global pandemic. Obesity has been associated with increased disease severity in COVID-19, and obesity is strongly associated with hepatic steatosis (HS). However, how HS alters the natural history of COVID-19 is not well characterized, especially in Western populatio...
acute liver injury;nafld;outcomes;sars-cov-2
Journal Article
Chen, Vincent L;Hawa, Fadi;Berinstein, Jeffrey A;Reddy, Chanakyaram A;Kassab, Ihab;Platt, Kevin D;Hsu, Chia-Yang;Steiner, Calen A;Louissaint, Jeremy;Gunaratnam, Naresh T;Sharma, Pratima
10.1007/s10620-020-06618-3
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Hepatic Steatosis Is Associated with Increased Disease Severity and Liver Injury in Coronavirus Disease-19. [Abstract]: BACKGROUND: Coronavirus disease-2019 (COVID-19) is a global pandemic. Obesity has been associated with increased disease severity in COVID-19, and obesity is strongly associated with hepatic ...
32,663,117
Glob Public Health
Governing COVID-19 without government in Brazil: Ignorance, neoliberal authoritarianism, and the collapse of public health leadership.
Brazil's governance of the COVID-19 pandemic has been described as nothing short of tragic by several commentators. President Jair Bolsonaro's dangerous brew of neoliberal authoritarianism, science denialism and ableism has plunged this country into catastrophe. In this article we argue that this form (or lack) of publ...
bolsonaro;brazil;covid-19;neoliberal authoritarianism;strategic ignorance
Journal Article;Video-Audio Media
Ortega, Francisco;Orsini, Michael
10.1080/17441692.2020.1795223
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Governing COVID-19 without government in Brazil: Ignorance, neoliberal authoritarianism, and the collapse of public health leadership. [Abstract]: Brazil's governance of the COVID-19 pandemic has been described as nothing short of tragic by several commentators. President Jair Bolsonaro's dangerous brew of neo...
33,045,467
EBioMedicine
A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection.
BACKGROUND: Real-time reverse transcription-PCR (rRT-PCR) has been the most effective and widely implemented diagnostic technology since the beginning of the COVID-19 pandemic. However, fuzzy rRT-PCR readouts with high Ct values are frequently encountered, resulting in uncertainty in diagnosis. METHODS: A Specific Enha...
covid-19;crispr diagnosis;cas12a;sars-cov-2;sena;rrt-pcr
Journal Article
Huang, Weiren;Yu, Lei;Wen, Donghua;Wei, Dong;Sun, Yangyang;Zhao, Huailong;Ye, Yu;Chen, Wei;Zhu, Yongqiang;Wang, Lijun;Wang, Li;Wu, Wenjuan;Zhao, Qianqian;Xu, Yong;Gu, Dayong;Nie, Guohui;Zhu, Dongyi;Guo, Zhongliang;Ma, Xiaoling;Niu, Liman;Huang, Yikun;Liu, Yuchen;Peng, Bo;Zhang, Renli;Zhang, Xiuming;Li, Dechang;Liu, Yan...
10.1016/j.ebiom.2020.103036
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection. [Abstract]: BACKGROUND: Real-time reverse transcription-PCR (rRT-PCR) has been the most effective and widely implemented diagnostic technology since the beginning of the COVID-19 pandemic. However, fuzzy rRT-PCR reado...
32,475,036
Dermatol Ther
Clinical efficacy, speed of improvement and safety of apremilast for the treatment of adult Psoriasis during COVID-19 pandemic.
Time to improvement is a crucial characteristic for effective treatments of chronic inflammatory conditions, such as psoriasis. Apremilast is a recently approved drug, belonging to the small molecule phosphodiesterase 4 inhibitors, whose optimal safety and efficacy profile is somewhat affected by slow activity rate in ...
covid-19;apremilast;efficacy;psoriasis;safety
Journal Article
Melis, Daniele;Mugheddu, Cristina;Sanna, Silvia;Atzori, Laura;Rongioletti, Franco
10.1111/dth.13722
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical efficacy, speed of improvement and safety of apremilast for the treatment of adult Psoriasis during COVID-19 pandemic. [Abstract]: Time to improvement is a crucial characteristic for effective treatments of chronic inflammatory conditions, such as psoriasis. Apremilast is a recently approved drug, bel...
32,916,067
Am Surg
The American College of Surgeons Response to the COVID-19 Pandemic (Part I): Cancer Care, COVID-19 Registry, Surgeon Wellness.
From the onset of the COVID-19 global pandemic of 2020, the American College of Surgeons has been a leader in disseminating reliable information on the nature of the crisis and assuring quality of surgical care during the enforced lockdown of inpatient and outpatient care.
american college of surgeons;covid-19;cancer;pandemic;surgeon;surgery;wellness
Journal Article
Wexner, Steven D;Nelson, Heidi;Stain, Steven C;Turner, Patricia L;Cortes-Guiral, Delia
10.1177/0003134820940771
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The American College of Surgeons Response to the COVID-19 Pandemic (Part I): Cancer Care, COVID-19 Registry, Surgeon Wellness. [Abstract]: From the onset of the COVID-19 global pandemic of 2020, the American College of Surgeons has been a leader in disseminating reliable information on the nature of the crisis...
32,472,745
Matern Child Nutr
SARS-CoV-2 and human milk: What is the evidence?
The novel coronavirus SARS-CoV-2 has emerged as one of the most compelling and concerning public health challenges of our time. To address the myriad issues generated by this pandemic, an interdisciplinary breadth of research, clinical and public health communities has rapidly engaged to collectively find answers and s...
covid-19;sars-cov-2;breast milk;breastfeeding;coronavirus;human milk;infectious disease
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Lackey, Kimberly A;Pace, Ryan M;Williams, Janet E;Bode, Lars;Donovan, Sharon M;Jarvinen, Kirsi M;Seppo, Antti E;Raiten, Daniel J;Meehan, Courtney L;McGuire, Mark A;McGuire, Michelle K
10.1111/mcn.13032
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: SARS-CoV-2 and human milk: What is the evidence? [Abstract]: The novel coronavirus SARS-CoV-2 has emerged as one of the most compelling and concerning public health challenges of our time. To address the myriad issues generated by this pandemic, an interdisciplinary breadth of research, clinical and public hea...
32,534,909
Chest
First Detection of SARS-CoV-2 by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Assay in Pleural Fluid.
Coronavirus disease 2019 (COVID-19) is a pandemic infection due to the spread of a novel coronavirus (severe acute respiratory syndrome coronavirus 2), resulting in a wide range of clinical features, from asymptomatic carriers to ARDS. The gold standard for diagnosis is nucleic acid detection by real-time reverse trans...
ct-guided biopsy;diagnostic yield;meta-analysis;pleural lesions;safety;ultrasound-guided biopsy
Case Reports;Journal Article
Mei, Federico;Bonifazi, Martina;Menzo, Stefano;Di Marco Berardino, Alessandro;Sediari, Michele;Paolini, Luca;Re, Antonina;Gonnelli, Francesca;Duranti, Claudia;Grilli, Martina;Vennarucci, Giacomo Spurio;Latini, Maria Agnese;Zuccatosta, Lina;Gasparini, Stefano
10.1016/j.chest.2020.05.583
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: First Detection of SARS-CoV-2 by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Assay in Pleural Fluid. [Abstract]: Coronavirus disease 2019 (COVID-19) is a pandemic infection due to the spread of a novel coronavirus (severe acute respiratory syndrome coronavirus 2), resulting in a wide range of cli...
32,779,342
J Obstet Gynaecol Res
Covid-19 pandemic and pregnancy.
At the end of 2019, a new coronavirus disease, COVID-19, emerged and quickly spread around the world. Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), the causative virus of this disease, belongs to the beta-coronavirus family, together with SARS and middle east respiratory syndrome, and has similar biolog...
covid-19;sars-cov-2;pregnancy
Journal Article
Hayakawa, Satoshi;Komine-Aizawa, Shihoko;Mor, Gil G
10.1111/jog.14384
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Covid-19 pandemic and pregnancy. [Abstract]: At the end of 2019, a new coronavirus disease, COVID-19, emerged and quickly spread around the world. Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), the causative virus of this disease, belongs to the beta-coronavirus family, together with SARS and mi...
32,634,126
J Clin Invest
SARS-CoV-2 viral load and antibody responses: the case for convalescent plasma therapy.
Most patients with COVID-19 lack antibody to SARS-CoV-2 in the first 10 days of illness while the virus drives disease pathogenesis. SARS-CoV-2 antibody deficiency in the setting of a tissue viral burden suggests that using an antibody as a therapeutic agent would augment the antiviral immune response. In this issue of...
Journal Article;Research Support, N.I.H., Extramural;Comment
Casadevall, Arturo;Joyner, Michael J;Pirofski, Liise-Anne
10.1172/JCI139760
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 viral load and antibody responses: the case for convalescent plasma therapy. [Abstract]: Most patients with COVID-19 lack antibody to SARS-CoV-2 in the first 10 days of illness while the virus drives disease pathogenesis. SARS-CoV-2 antibody deficiency in the setting of a tissue viral burden suggest...
32,534,912
J Am Pharm Assoc (2003)
The pivotal role of pharmacists during the 2019 coronavirus pandemic.
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected over 3 million people worldwide with an estimated mortality rate of 5%. Owing to the diversity of training and the variety of positions within the pharmacy department, pharmacists are uni...
Journal Article
Li, Matthew;Razaki, Hamid;Mui, Victoria;Rao, Premprakash;Brocavich, Sheila
10.1016/j.japh.2020.05.017
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The pivotal role of pharmacists during the 2019 coronavirus pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected over 3 million people worldwide with an estimated mortality rate of 5%. Owing to the diversity o...
32,584,103
Psychol Trauma
A culturally-competent approach to emergency management: What lessons can we learn from the COVID-19?
The COVID-19 pandemic, like other disasters, is exposing and exacerbating social, economic, and health care inequalities. Although the ethical and clinical imperative of providing culturally-competent health care has long been recognized, the influence of culturally-competent interventions within emergency management h...
Journal Article
Slobodin, Ortal;Cohen, Odeya
10.1037/tra0000790
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A culturally-competent approach to emergency management: What lessons can we learn from the COVID-19? [Abstract]: The COVID-19 pandemic, like other disasters, is exposing and exacerbating social, economic, and health care inequalities. Although the ethical and clinical imperative of providing culturally-compet...
32,759,267
Antimicrob Agents Chemother
Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is already responsible for far more deaths than previous pathogenic coronaviruses (CoVs) from 2002 and 2012. The identification of clinically approved drugs to be repurposed to combat 2019 CoV disease (COVID-19) would allow the rapid implementation of potenti...
covid-19;sars-cov-2;antiviral;atazanavir;coronavirus
Journal Article;Research Support, Non-U.S. Gov't
Fintelman-Rodrigues, Natalia;Sacramento, Carolina Q;Ribeiro Lima, Carlyle;Souza da Silva, Franklin;Ferreira, Andre C;Mattos, Mayara;de Freitas, Caroline S;Cardoso Soares, Vinicius;da Silva Gomes Dias, Suelen;Temerozo, Jairo R;Miranda, Milene D;Matos, Aline R;Bozza, Fernando A;Carels, Nicolas;Alves, Carlos Roberto;Sique...
10.1128/AAC.00825-20
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is already responsible for far more deaths than previous pathogenic coronaviruses (CoVs) from 2002 and 2012. The ...
32,508,311
Endocr Relat Cancer
COVID-19 and androgen-targeted therapy for prostate cancer patients.
The current pandemic (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health challenge with active development of antiviral drugs and vaccines seeking to reduce its significant disease burden. Early reports have confirmed that transmembrane serine protease 2 (TMPRSS2) and an...
ace2;covid-19;sars-cov-2;tmprss2;androgen signaling;prostate cancer
Journal Article;Review
Bhowmick, Neil A;Oft, Jillian;Dorff, Tanya;Pal, Sumanta;Agarwal, Neeraj;Figlin, Robert A;Posadas, Edwin M;Freedland, Stephen J;Gong, Jun
10.1530/ERC-20-0165
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 and androgen-targeted therapy for prostate cancer patients. [Abstract]: The current pandemic (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health challenge with active development of antiviral drugs and vaccines seeking to reduce its significant disease ...
32,794,949
Phys Rev E
Self-isolation or borders closing: What prevents the spread of the epidemic better?
Pandemic propagation of COVID-19 motivated us to discuss the impact of the human network clustering on epidemic spreading. Today, there are two clustering mechanisms which prevent of uncontrolled disease propagation in a connected network: an "internal" clustering, which mimics self-isolation (SI) in local naturally ar...
Journal Article
Valba, O;Avetisov, V;Gorsky, A;Nechaev, S
10.1103/PhysRevE.102.010401
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Self-isolation or borders closing: What prevents the spread of the epidemic better? [Abstract]: Pandemic propagation of COVID-19 motivated us to discuss the impact of the human network clustering on epidemic spreading. Today, there are two clustering mechanisms which prevent of uncontrolled disease propagation...
32,347,991
Head Neck
Health workers' safety during tracheostomy in COVID-19 patients: Homemade protective screen.
As an aerosol and droplets generating procedure, tracheostomy increases contamination risks for health workers in the coronavirus disease context. To preserve the health care system capacity and to limit virus cross-transmission, protecting caregivers against coronavirus infection is of critical importance. We report t...
covid-19;caregivers;safety;tracheostomy;transmission
Journal Article;Review
Cordier, Pierre-Yves;De La Villeon, Bruno;Martin, Edouard;Goudard, Yvain;Haen, Pierre
10.1002/hed.26222
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Health workers' safety during tracheostomy in COVID-19 patients: Homemade protective screen. [Abstract]: As an aerosol and droplets generating procedure, tracheostomy increases contamination risks for health workers in the coronavirus disease context. To preserve the health care system capacity and to limit vi...
33,050,499
Diagnostics (Basel)
Invasive Pulmonary Aspergillosis in Patients with SARS-CoV-2 Infection: A Systematic Review of the Literature.
In this systematic review, we investigate the epidemiology, pathogenesis, risk factors, clinical manifestations, diagnosis and treatment of COVID-19-associated pulmonary aspergillosis (CAPA). We identified 85 cases from 22 studies. The frequency of CAPA is currently unknown but ranges between <5% to >30% in different c...
capa;covid-19;sars-cov-2;aspergillosis;aspergillus
Journal Article;Review
Apostolopoulou, Anna;Esquer Garrigos, Zerelda;Vijayvargiya, Prakhar;Lerner, Alexis Hope;Farmakiotis, Dimitrios
10.3390/diagnostics10100807
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Invasive Pulmonary Aspergillosis in Patients with SARS-CoV-2 Infection: A Systematic Review of the Literature. [Abstract]: In this systematic review, we investigate the epidemiology, pathogenesis, risk factors, clinical manifestations, diagnosis and treatment of COVID-19-associated pulmonary aspergillosis (CAP...
32,979,938
Cell Rep
Evasion of Type I Interferon by SARS-CoV-2.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating viral evasion of immune response are lacking. Here, we use unbiased screening to identify SARS-CoV-2 proteins that antagonize type I interferon (IFN-I) ...
covid-19;sars-cov-2;coronavirus disease 2019;immune evasion;interferon;replicon;severe acute respiratory syndrome coronavirus 2
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Xia, Hongjie;Cao, Zengguo;Xie, Xuping;Zhang, Xianwen;Chen, John Yun-Chung;Wang, Hualei;Menachery, Vineet D;Rajsbaum, Ricardo;Shi, Pei-Yong
10.1016/j.celrep.2020.108234
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Evasion of Type I Interferon by SARS-CoV-2. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating viral evasion of immune response are lacking. Here, we use unbiased screening to identi...
33,031,948
Clin Microbiol Infect
Follow-up of adults with noncritical COVID-19 two months after symptom onset.
OBJECTIVES: To describe the clinical evolution and predictors of symptom persistence during 2 months' follow-up in adults with noncritical coronavirus disease 2019 (COVID-19). METHODS: We performed descriptive clinical follow-up (day (D) 7, D30 and D60) of 150 patients with noncritical COVID-19 confirmed by real-time r...
description;follow-up;mild covid-19;moderate covid-19;noncritical covid-19;outcomes;persisting symptoms
Journal Article
Carvalho-Schneider, Claudia;Laurent, Emeline;Lemaignen, Adrien;Beaufils, Emilie;Bourbao-Tournois, Celine;Laribi, Said;Flament, Thomas;Ferreira-Maldent, Nicole;Bruyere, Franck;Stefic, Karl;Gaudy-Graffin, Catherine;Grammatico-Guillon, Leslie;Bernard, Louis
10.1016/j.cmi.2020.09.052
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Follow-up of adults with noncritical COVID-19 two months after symptom onset. [Abstract]: OBJECTIVES: To describe the clinical evolution and predictors of symptom persistence during 2 months' follow-up in adults with noncritical coronavirus disease 2019 (COVID-19). METHODS: We performed descriptive clinical fo...
33,063,792
IUCrJ
Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy.
Dexamethasone, a widely used corticosteroid, has recently been reported as the first drug to increase the survival chances of patients with severe COVID-19. Therapeutic agents, including dexamethasone, are mostly transported through the body by binding to serum albumin. Here, the first structure of serum albumin in com...
covid-19;sars-cov-2;albumin;coronavirus;dexamethasone;drug transport
Journal Article
Shabalin, Ivan G;Czub, Mateusz P;Majorek, Karolina A;Brzezinski, Dariusz;Grabowski, Marek;Cooper, David R;Panasiuk, Mateusz;Chruszcz, Maksymilian;Minor, Wladek
10.1107/S2052252520012944
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy. [Abstract]: Dexamethasone, a widely used corticosteroid, has recently been reported as the first drug to increase the survival chances of patients with severe COVID-19. Therapeutic agents, including dexamethasone, are mostly tra...
32,925,755
Medicine (Baltimore)
Effect of respiratory rehabilitation training on elderly patients with COVID-19: A protocol for systematic review and meta-analysis.
BACKGROUND: Patients with the Corona Virus Disease 2019 (COVID-19) often see their respiratory, physical, and psychological functions impaired to varying degrees, especially for the elderly patients. Timely respiratory rehabilitation intervention for such patients may improve their prognoses. However, its relative effe...
Journal Article
Yan, Huan;Ouyang, Yonghong;Wang, Lang;Luo, Xiangjun;Zhan, Qian
10.1097/MD.0000000000022109
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effect of respiratory rehabilitation training on elderly patients with COVID-19: A protocol for systematic review and meta-analysis. [Abstract]: BACKGROUND: Patients with the Corona Virus Disease 2019 (COVID-19) often see their respiratory, physical, and psychological functions impaired to varying degrees, esp...
32,771,272
Transfus Med Rev
A Scoping Review of Registered Clinical Trials of Convalescent Plasma for COVID-19 and a Framework for Accelerated Synthesis of Trial Evidence (FAST Evidence).
Many parallel studies of convalescent plasma with modest enrolment projections have been launched for the treatment of COVID-19. By pooling data from multiple parallel studies that are similar, we can increase the effective sample size and achieve enough statistical power to determine effectiveness more quickly through...
acute respiratory distress syndrome;covid-19;clinical trials;convalescent plasma;systematic review
Journal Article;Review;Systematic Review
Zheng, Katina;Liao, Gary;Lalu, Manoj M;Tinmouth, Alan;Fergusson, Dean A;Allan, David S
10.1016/j.tmrv.2020.06.005
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Scoping Review of Registered Clinical Trials of Convalescent Plasma for COVID-19 and a Framework for Accelerated Synthesis of Trial Evidence (FAST Evidence). [Abstract]: Many parallel studies of convalescent plasma with modest enrolment projections have been launched for the treatment of COVID-19. By pooling...
32,840,002
Transfusion
Persistence of SARS-CoV-2 nasopharyngeal swab PCR positivity in COVID-19 convalescent plasma donors.
BACKGROUND: Nucleic acid persists after symptom resolution and infectivity for many viral infections via delayed clearance of nucleic acid fragments, non-infectious particles, or transmissible virus. For Coronavirus Disease 2019 (COVID-19), the relationship between nasopharyngeal (NP) swab positivity, the development o...
Journal Article;Research Support, Non-U.S. Gov't
Ikegami, Sachie;Benirschke, Robert;Flanagan, Tara;Tanna, Nicole;Klein, Tovah;Elue, Rita;Debosz, Patricia;Mallek, Jessica;Wright, Gregory;Guariglia, Perry;Kang, Jason;Gniadek, Thomas J
10.1111/trf.16015
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Persistence of SARS-CoV-2 nasopharyngeal swab PCR positivity in COVID-19 convalescent plasma donors. [Abstract]: BACKGROUND: Nucleic acid persists after symptom resolution and infectivity for many viral infections via delayed clearance of nucleic acid fragments, non-infectious particles, or transmissible virus...
33,004,167
Best Pract Res Clin Anaesthesiol
The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology.
Coronavirus disease 2019 (COVID-19) is a new disease with different phases that can be catastrophic for subpopulations of patients with cardiovascular and pulmonary disease states at baseline. Appreciation for these different phases and treatment modalities, including manipulation of ventilatory settings and therapeuti...
ards;peep;cardiovascular disease;lung physiology
Journal Article;Review
Perchiazzi, Gaetano;Pellegrini, Mariangela;Chiodaroli, Elena;Urits, Ivan;Kaye, Alan D;Viswanath, Omar;Varrassi, Giustino;Puntillo, Filomena
10.1016/j.bpa.2020.07.007
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology. [Abstract]: Coronavirus disease 2019 (COVID-19) is a new disease with different phases that can be catastrophic for subpopulations of patients with cardiovascular and...
32,333,929
Chest
Practical Considerations for the Diagnosis and Treatment of Fibrotic Interstitial Lung Disease During the Coronavirus Disease 2019 Pandemic.
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has affected virtually all aspects of patient care. Health-care systems around the world are trying simultaneously to treat patients with COVID-19, prepare for its long-term impacts, and treat patients with othe...
coronavirus disease;diagnosis;interstitial lung disease;treatment
Journal Article;Research Support, Non-U.S. Gov't;Review
Wong, Alyson W;Fidler, Lee;Marcoux, Veronica;Johannson, Kerri A;Assayag, Deborah;Fisher, Jolene H;Hambly, Nathan;Kolb, Martin;Morisset, Julie;Shapera, Shane;Ryerson, Christopher J
10.1016/j.chest.2020.04.019
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Practical Considerations for the Diagnosis and Treatment of Fibrotic Interstitial Lung Disease During the Coronavirus Disease 2019 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has affected virtually all aspects of patient car...
32,717,211
Lancet Respir Med
Particle sizes of infectious aerosols: implications for infection control.
The global pandemic of COVID-19 has been associated with infections and deaths among health-care workers. This Viewpoint of infectious aerosols is intended to inform appropriate infection control measures to protect health-care workers. Studies of cough aerosols and of exhaled breath from patients with various respirat...
Journal Article;Research Support, N.I.H., Intramural;Review
Fennelly, Kevin P
10.1016/S2213-2600(20)30323-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Particle sizes of infectious aerosols: implications for infection control. [Abstract]: The global pandemic of COVID-19 has been associated with infections and deaths among health-care workers. This Viewpoint of infectious aerosols is intended to inform appropriate infection control measures to protect health-c...
32,710,937
Clin Immunol
Micronutrients as immunomodulatory tools for COVID-19 management.
COVID-19 rapidly turned to a global pandemic posing lethal threats to overwhelming health care capabilities, despite its relatively low mortality rate. The clinical respiratory symptoms include dry cough, fever, anosmia, breathing difficulties, and subsequent respiratory failure. No known cure is available for COVID-19...
covid-19;immunomodulation;nutrients;sars-cov-2;trace elements;vitamins
Journal Article;Review
Gasmi, Amin;Tippairote, Torsak;Mujawdiya, Pavan Kumar;Peana, Massimiliano;Menzel, Alain;Dadar, Maryam;Gasmi Benahmed, Asma;Bjorklund, Geir
10.1016/j.clim.2020.108545
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Micronutrients as immunomodulatory tools for COVID-19 management. [Abstract]: COVID-19 rapidly turned to a global pandemic posing lethal threats to overwhelming health care capabilities, despite its relatively low mortality rate. The clinical respiratory symptoms include dry cough, fever, anosmia, breathing di...
33,052,078
Bosn J Basic Med Sci
Increasing the efficiency of mechanical ventilators during pandemics through additive manufacturing.
COVID-19 pandemic tested medical facilities readiness in terms of number of available mechanical ventilators. Most countries raced to stock up on ventilators, which created a surge in demand and short in supply. Other means of coping with the demand were proposed, such as using additive manufacturing. This paper is to ...
Journal Article
Alwasel, Abdullatif;Zaky, Jean;Alhussaini, Khalid;Alossimi, Bandr;Alharbi, Turki
10.17305/bjbms.2020.5165
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Increasing the efficiency of mechanical ventilators during pandemics through additive manufacturing. [Abstract]: COVID-19 pandemic tested medical facilities readiness in terms of number of available mechanical ventilators. Most countries raced to stock up on ventilators, which created a surge in demand and sho...
33,047,335
Anaesthesia
The impact of protocol-based high-intensity pharmacological thromboprophylaxis on thrombotic events in critically ill COVID-19 patients.
The reported incidence rate of venous and arterial thrombotic events in critically ill patients with COVID-19 infections is high, ranging from 20% to 60%. We adopted a patient-tailored thromboprophylaxis protocol based on clinical and laboratory presentations for these patients in our institution. We hypothesised that ...
covid-19;d-dimer;deep venous thrombosis;pulmonary embolism;thromboembolic events
Journal Article
Atallah, B;Sadik, Z G;Salem, N;El Nekidy, W S;Almahmeed, W;Park, W M;Cherfan, A;Hamed, F;Mallat, J
10.1111/anae.15300
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The impact of protocol-based high-intensity pharmacological thromboprophylaxis on thrombotic events in critically ill COVID-19 patients. [Abstract]: The reported incidence rate of venous and arterial thrombotic events in critically ill patients with COVID-19 infections is high, ranging from 20% to 60%. We adop...
32,387,156
J Hand Surg Am
The Impact of Coronavirus Disease 2019 (COVID-19) on the Practice of Hand Surgery in Singapore.
The coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving. Tan Tock Seng Hospital and the National Centre for Infectious Disease see the majority of confirmed and suspected cases in Singapore. This article describes the impact of COVID-19 on the practice of hand and reconstructive microsurgery (HRM) in our i...
covid-19;coronavirus;hand;microsurgery;surgery
Journal Article;Review
Hwee, Jolie;Chiew, Jean;Sechachalam, Sreedharan
10.1016/j.jhsa.2020.04.023
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Impact of Coronavirus Disease 2019 (COVID-19) on the Practice of Hand Surgery in Singapore. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving. Tan Tock Seng Hospital and the National Centre for Infectious Disease see the majority of confirmed and suspected cases in Singapore....
32,566,564
Ann Transl Med
Effectiveness and safety of glucocorticoids to treat COVID-19: a rapid review and meta-analysis.
Background: Glucocorticoids are widely used in the treatment of various pulmonary inflammatory diseases, but they are also often accompanied by significant adverse reactions. Published guidelines point out that low dose and short duration systemic glucocorticoid therapy may be considered for patients with rapidly progr...
coronavirus disease 2019 (covid-19);glucocorticoids;meta-analysis;rapid review
Journal Article
Lu, Shuya;Zhou, Qi;Huang, Liping;Shi, Qianling;Zhao, Siya;Wang, Zijun;Li, Weiguo;Tang, Yuyi;Ma, Yanfang;Luo, Xufei;Fukuoka, Toshio;Ahn, Hyeong Sik;Lee, Myeong Soo;Luo, Zhengxiu;Liu, Enmei;Chen, Yaolong;Zhou, Chenyan;Peng, Donghong
10.21037/atm-20-3307
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effectiveness and safety of glucocorticoids to treat COVID-19: a rapid review and meta-analysis. [Abstract]: Background: Glucocorticoids are widely used in the treatment of various pulmonary inflammatory diseases, but they are also often accompanied by significant adverse reactions. Published guidelines point ...
32,943,630
Nat Commun
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood.
Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific antibodies in different populations has remained unclear. Here, we report very low SARS-CoV-2 seroprevalence in two San Francisco Bay Area populations. Seroreactivity was 0.26% in 387 hospitalized patients admitted ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Ng, Dianna L;Goldgof, Gregory M;Shy, Brian R;Levine, Andrew G;Balcerek, Joanna;Bapat, Sagar P;Prostko, John;Rodgers, Mary;Coller, Kelly;Pearce, Sandra;Franz, Sergej;Du, Li;Stone, Mars;Pillai, Satish K;Sotomayor-Gonzalez, Alicia;Servellita, Venice;Martin, Claudia Sanchez San;Granados, Andrea;Glasner, Dustin R;Han, Lucy ...
10.1038/s41467-020-18468-8
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood. [Abstract]: Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific antibodies in different populations has remained unclear. Here, we report very low SARS-CoV-2 seroprevalence in tw...
32,974,227
Med J Islam Repub Iran
Attitudinal, regional and sex related vulnerabilities to COVID-19: Considerations for early flattening of curve in Nigeria.
Background: In Nigeria, the policies and interventions due to the COVID-19 pandemic are majorly directed at businesses and relief. There are no clear plans to identify individuals with comorbidities associated with high morbidity and fatality rates. This paper identifies comorbidities associated with high morbidity and...
covid-19;cancer;cardiac injury;comorbidities;fatality
Journal Article
Okoye, Jude Ogechukwu
10.34171/mjiri.34.61
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Attitudinal, regional and sex related vulnerabilities to COVID-19: Considerations for early flattening of curve in Nigeria. [Abstract]: Background: In Nigeria, the policies and interventions due to the COVID-19 pandemic are majorly directed at businesses and relief. There are no clear plans to identify individ...
32,712,775
Eur J Trauma Emerg Surg
Novel coronavirus and trauma surgery: successful infection control from a level I trauma centre.
PURPOSE: In the absence of effective treatment options, the recent SARS-CoV2 pandemic poses a great challenge to the health and social sectors worldwide. Hereby, we would like to share our proposals in the hope that it will prove helpful for our colleagues in this difficult time. METHODS: The present recommendations ar...
covid-19;pandemic;patient care protocol;sars-cov2;trauma
Journal Article
Javor, Peter;Varga, Endre;Fekete, Karoly;Toth, Ferenc;Hartmann, Petra
10.1007/s00068-020-01435-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Novel coronavirus and trauma surgery: successful infection control from a level I trauma centre. [Abstract]: PURPOSE: In the absence of effective treatment options, the recent SARS-CoV2 pandemic poses a great challenge to the health and social sectors worldwide. Hereby, we would like to share our proposals in ...
32,901,399
Neurol Sci
Fulminant encephalitis as a sole manifestation of COVID-19.
Novel coronavirus (SARS-CoV-2) occurred in December 2019 in Wuhan, China, and has become a global health emergency. Coronavirus primarily is a respiratory virus, but it has been detected in the brain and cerebrospinal fluid of infected individuals. The present report describes a case of fulminant encephalitis in a pati...
covid-19;encephalitis;fulminant;sole presentation
Case Reports;Journal Article
Etemadifar, Masoud;Salari, Mehri;Murgai, Aditya Ashok;Hajiahmadi, Somayeh
10.1007/s10072-020-04712-y
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Fulminant encephalitis as a sole manifestation of COVID-19. [Abstract]: Novel coronavirus (SARS-CoV-2) occurred in December 2019 in Wuhan, China, and has become a global health emergency. Coronavirus primarily is a respiratory virus, but it has been detected in the brain and cerebrospinal fluid of infected ind...
32,365,180
Mol Hum Reprod
Potential influence of COVID-19/ACE2 on the female reproductive system.
The 2019 novel coronavirus (2019-nCoV) appeared in December 2019 and then spread throughout the world rapidly. The virus invades the target cell by binding to angiotensin-converting enzyme (ACE) 2 and modulates the expression of ACE2 in host cells. ACE2, a pivotal component of the renin-angiotensin system, exerts its p...
2019-ncov;ang-(1-7);covid-19;angiotensin ii;angiotensin-converting enzyme 2;breastfeeding;coronavirus;female reproductive system;pregnancy
Journal Article;Research Support, Non-U.S. Gov't;Review
Jing, Yan;Run-Qian, Li;Hao-Ran, Wang;Hao-Ran, Chen;Ya-Bin, Liu;Yang, Gao;Fei, Chen
10.1093/molehr/gaaa030
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Potential influence of COVID-19/ACE2 on the female reproductive system. [Abstract]: The 2019 novel coronavirus (2019-nCoV) appeared in December 2019 and then spread throughout the world rapidly. The virus invades the target cell by binding to angiotensin-converting enzyme (ACE) 2 and modulates the expression o...
33,078,425
J Surg Oncol
Impact of the COVID-19 pandemic during Spain's state of emergency on the diagnosis of colorectal cancer.
INTRODUCTION: We evaluate the impact of COVID-epidemic in colorectal cancer (CRC) diagnosis during Spain's state of emergency. METHODS: We compared newly diagnosed patients with patients diagnosed in the same period of 2019. RESULTS: A new diagnosis of CRC decreased 48% with a higher rate of patients diagnosed in the e...
covid-19;colorectal cancer;colorectal cancer diagnosis;multidisciplinary team
Journal Article;Review
Suarez, Javier;Mata, Elena;Guerra, Ana;Jimenez, Gloria;Montes, Marta;Arias, Fernando;Ciga, Miguel A;Ursua, Eugenia;Ederra, Maria;Arin, Benat;Laiglesia, Matilde;Sanz, Asuncion;Vera, Ruth
10.1002/jso.26263
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of the COVID-19 pandemic during Spain's state of emergency on the diagnosis of colorectal cancer. [Abstract]: INTRODUCTION: We evaluate the impact of COVID-epidemic in colorectal cancer (CRC) diagnosis during Spain's state of emergency. METHODS: We compared newly diagnosed patients with patients diagnos...
32,714,844
Case Rep Womens Health
Obstetric and intensive-care strategies in a high-risk pregnancy with critical respiratory failure due to COVID-19: A case report.
Background: With the disease burden increasing daily, there is a lack of evidence regarding the impact of COVID-19 in pregnancy. Healthy pregnant women are still not regarded as a susceptible group despite physiological changes that make pregnant women more vulnerable to severe infection. However, high-risk pregnancies...
covid-19;coronavirus;intubation;pregnancy;sars-cov-2
Case Reports
Kolkova, Zuzana;Bjurstrom, Martin F;Lansberg, John-Kalle;Svedas, Eimantas;Hamer, Maria Andrada;Hansson, Stefan R;Herbst, Andreas;Zaigham, Mehreen
10.1016/j.crwh.2020.e00240
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Obstetric and intensive-care strategies in a high-risk pregnancy with critical respiratory failure due to COVID-19: A case report. [Abstract]: Background: With the disease burden increasing daily, there is a lack of evidence regarding the impact of COVID-19 in pregnancy. Healthy pregnant women are still not re...
32,922,024
J Multidiscip Healthc
Evaluation of Knowledge and Preparedness Among Indian Dentists During the Current COVID-19 Pandemic: A Cross-Sectional Study.
Purpose: The current scenario of the COVID-19 pandemic has forced dentists to prepare themselves by updating their knowledge and receive training to face the present and after effects of COVID-19. The present survey was thus conducted to assess the knowledge, risk perception, attitude, and preparedness of the dentists ...
asian;awareness;corona virus;dentistry;healthcare workers
Journal Article
Arora, Suraj;Abullais Saquib, Shahabe;Attar, Nilofar;Pimpale, Sandeep;Saifullah Zafar, Khwaja;Saluja, Priyanka;M Abdulla, Anshad;Shamsuddin, Shaheen
10.2147/JMDH.S268891
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Evaluation of Knowledge and Preparedness Among Indian Dentists During the Current COVID-19 Pandemic: A Cross-Sectional Study. [Abstract]: Purpose: The current scenario of the COVID-19 pandemic has forced dentists to prepare themselves by updating their knowledge and receive training to face the present and aft...
32,444,569
J Neonatal Perinatal Med
Management of the mother-infant dyad with suspected or confirmed SARS-CoV-2 infection in a highly epidemic context.
In the context of SARS-CoV-2 pandemic, the hospital management of mother-infant pairs poses to obstetricians and neonatologists previously unmet challenges. In Lombardy, Northern Italy, 59 maternity wards networked to organise the medical assistance of mothers and neonates with suspected or confirmed SARS-CoV-2 infecti...
covid-19;nicu;sars-cov-2;breastfeeding;coronavirus;delivery room;neonate;rooming-in
Journal Article
Pietrasanta, C;Pugni, L;Ronchi, A;Schena, F;Davanzo, R;Gargantini, G;Ferrazzi, E;Mosca, F
10.3233/NPM-200478
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of the mother-infant dyad with suspected or confirmed SARS-CoV-2 infection in a highly epidemic context. [Abstract]: In the context of SARS-CoV-2 pandemic, the hospital management of mother-infant pairs poses to obstetricians and neonatologists previously unmet challenges. In Lombardy, Northern Ital...
32,850,218
Cureus
Covid-19 Presenting as Acute Limb Ischemia.
Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and represents a potentially fatal disease. COVID-19 is associated with a hypercoagulable state leading to increased incidence of venous thromboembolism. Arterial thrombosis has been reported, but the prevalenc...
acute limb ischemia;arterial thrombosis;covid-19;sars-cov-2 (severe acute respiratory syndrome coronavirus 2;thrombosis
Case Reports
Singh, Balraj;Kaur, Parminder;Ajdir, Nora;Gupta, Sachin;Maroules, Michael
10.7759/cureus.9344
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Covid-19 Presenting as Acute Limb Ischemia. [Abstract]: Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and represents a potentially fatal disease. COVID-19 is associated with a hypercoagulable state leading to increased incidence of venous thromboe...
32,360,420
Cytokine Growth Factor Rev
Cytokine storm intervention in the early stages of COVID-19 pneumonia.
Clinical intervention in patients with corona virus disease 2019 (COVID-19) has demonstrated a strong upregulation of cytokine production in patients who are critically ill with SARS-CoV2-induced pneumonia. In a retrospective study of 41 patients with COVID-19, most patients with SARS-CoV-2 infection developed mild sym...
covid-19;cytokine storm;inflammation;lung damage;sars-cov2
Journal Article;Review
Sun, Xinjuan;Wang, Tianyuan;Cai, Dayong;Hu, Zhiwei;Chen, Jin'an;Liao, Hui;Zhi, Liming;Wei, Hongxia;Zhang, Zhihong;Qiu, Yuying;Wang, Jing;Wang, Aiping
10.1016/j.cytogfr.2020.04.002
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Cytokine storm intervention in the early stages of COVID-19 pneumonia. [Abstract]: Clinical intervention in patients with corona virus disease 2019 (COVID-19) has demonstrated a strong upregulation of cytokine production in patients who are critically ill with SARS-CoV2-induced pneumonia. In a retrospective st...