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https://openalex.org/W3179839637
https://iris.uniroma1.it/bitstream/11573/1562347/3/Pascarella_SARS%e2%80%90CoV%e2%80%902%20B.1.617_2021.pdf
English
null
SARS‐CoV‐2 B.1.617 Indian variants: Are electrostatic potential changes responsible for a higher transmission rate?
Journal of medical virology
2,021
cc-by
4,179
J M d Vi l 2021 1 6 il li lib /j l/j | 1 This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2021 The Authors. Journal of Medical Virology Published by Wiley Periodical...
https://openalex.org/W4389731129
http://j.uniyar.ac.ru/index.php/vyrgu/article/download/1462/1239
Russian
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Historical trends in the study of the phenomenon of wisdom in psychological science
Vestnik Âroslavskogo gosudarstvennogo universiteta imeni P.G. Demidova. Seriâ, Gumanitarnye nauki/Vestnik Âroslavskogo gosudarstvennogo universiteta im. P. G. Demidova. Seriâ, Gumanitarnye nauki
2,023
cc-by
4,152
Historical trends in the study of the phenomenon of wisdom in psychological science N. N. Mekhtikhanova1 1P. G. Demidov Yaroslavl state University, 14 Sovetskaya str., Yaroslsvl 150003, Russian Federation DOI: 10.18255/1996-5648-2023-4-620-630 Research article Full text in Russian © Yaroslavl State University, 2023 ...
https://openalex.org/W2090933140
https://europepmc.org/articles/pmc3733502?pdf=render
English
null
Joint action on monitoring injuries in Europe (JAMIE)
Archives of public health
2,012
cc-by
4,441
Rogmans Archives of Public Health 2012, 70:19 http://www.archpublichealth.com/content/70/1/19 Rogmans Archives of Public Health 2012, 70:19 http://www.archpublichealth.com/content/70/1/19 ARCHIVES OF PUBLIC HEALTH Open Access RESEARCH © 2012 Rogmans; licensee BioMed Central Ltd. This is an Open Access article distribu...
https://openalex.org/W1994948141
https://www.nature.com/articles/srep09974.pdf
English
null
Effects of substrate conductivity on cell morphogenesis and proliferation using tailored, atomic layer deposition-grown ZnO thin films
Scientific reports
2,015
cc-by
10,034
OPEN SUBJECT AREAS: FOCAL ADHESION MECHANOTRANSDUCTION SYNTHESIS AND PROCESSING Won Jin Choi1*, Jongjin Jung2*, Sujin Lee3*, Yoon Jang Chung1, Cheol-Soo Yang1, Young Kuk Lee1, You-Seop Lee4, Joung Kyu Park2, Hyuk Wan Ko3 & Jeong-O Lee1 Received 28 October 2014 Accepted 24 March 2015 Published 21 April 2015 1Advanced...
https://openalex.org/W4381684233
https://jurnaldrpm.budiluhur.ac.id/index.php/Kresna/article/download/65/110
Malay
null
Peningkatan Keterampilan Microsoft Word dan Powerpoint Untuk Staf Administrasi Pada Gereja Orthodox Indonesia
Kresna
2,023
cc-by-sa
3,421
Abstrak Kebutuhan lembaga atau organisasi masyarakat di era informasi saat ini adalah bagaimana mampu membuat laporan dalam bentuk digital dan juga mampu menampilkannya dalam bentuk digital. Sayangnya, kebutuhan tersebut masih belum dirasakan oleh masyarakat luas. Mitra pengabdian kepada masyarakat (PKM) saat ini ada...
https://openalex.org/W2275096063
https://pubs.rsc.org/en/content/articlepdf/2016/ra/c6ra90016j
English
null
Correction: Phase transformation-controlled synthesis of CuO nanostructures and their application as an improved material in a carbon-based modified electrode
RSC advances
2,016
cc-by
467
aKey Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou, 730070, China. E-mail: xuezh@nwnu.edu.cn; luxq@nwnu.edu.cn; Fax: +86 9317971323; Tel: +86 9317975276 bLanzhou City University, Lanzhou, 730070, China RSC ...
https://openalex.org/W3041513180
https://hal.archives-ouvertes.fr/hal-03353129/document
English
null
Performance of Notched Connectors for CLT-Concrete Composite Floors
Buildings
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cc-by
15,725
To cite this version: Minh-Van Thai, Sylvain Menard, Sidi Mohammed Elachachi, Philippe Galimard. Performance of Notched Connectors for CLT-Concrete Composite Floors. Buildings, 2020, 10 (7), pp.122. ￿10.3390/buildings10070122￿. ￿hal-03353129￿ Distributed under a Creative Commons Attribution 4.0 International License Re...
W4385953024.txt
https://cjme.springeropen.com/counter/pdf/10.1186/s10033-023-00905-6
en
NuBot: A Magnetic Adhesion Robot with Passive Suspension to Inspect the Steel Lining
Chinese journal of mechanical engineering/Chinese Journal of Mechanical Engineering
2,023
cc-by
10,620
Xu et al. Chinese Journal of Mechanical Engineering (2023) 36:90 https://doi.org/10.1186/s10033-023-00905-6 Chinese Journal of Mechanical Engineering Open Access ORIGINAL ARTICLE NuBot: A Magnetic Adhesion Robot with Passive Suspension to Inspect the Steel Lining Hao Xu1, Youcheng Han1, Mingda He1, Yinghui Li1 and ...
W4287889745.txt
https://aclanthology.org/2022.naacl-main.46.pdf
en
User-Centric Gender Rewriting
Proceedings of the 2022 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies
2,022
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9,093
User-Centric Gender Rewriting Bashar Alhafni, Nizar Habash, Houda Bouamor† Computational Approaches to Modeling Language Lab New York University Abu Dhabi † Carnegie Mellon University in Qatar {alhafni,nizar.habash}@nyu.edu, hbouamor@qatar.cmu.edu Abstract output, NLP systems should be designed to produce outputs tha...
https://openalex.org/W4393443557
https://jurnal.unmer.ac.id/index.php/jpkm/article/download/12128/pdf
English
null
Training hotel staff in early emergency management to enhance tourist comfort at Ubud Raya Resort area
Abdimas
2,024
cc-by-sa
5,305
ABDIMAS: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol.9(1) February 2024, 56-64 p-ISSN: 2721-138X e-ISSN: 2548-7159 http://jurnal.unmer.ac.id/index.php/jpkm LPPM UNMER MALANG ABDIMAS: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol.9(1) February 2024, 56-64 p-ISSN: 2721-138X e-ISSN: 2548-7...
https://openalex.org/W4285306231
https://www.e3s-conferences.org/10.1051/e3sconf/202235201077/pdf
English
null
Numerical simulation of polymer flooding in water flooding reservoir
E3S web of conferences
2,022
cc-by
1,997
Numerical simulation of polymer flooding in water flooding reservoir Xiaofei Sun*, Qingquan Zhang, Zhiyi Teng, Xueqian Wang, and Jiaming Cai etroleum Engineering, China University of Petroleum (East China), Qingdao, China Abstract. Different influencing factors in the process of polymer flooding have different degrees...
https://openalex.org/W2101444245
https://www.bio-conferences.org/articles/bioconf/pdf/2011/01/bioconf_skills_00029.pdf
English
null
Design Guidelines for the Development of Virtual Reality and Augmented Reality Training Systems for Maintenance and Assembly Tasks
Bio web of conferences/BIO web of conferences
2,011
cc-by
2,790
Abstract The current work describes design guidelines for the development of Virtual Reality (VR) and Augmented Reality (AR) platforms to train technicians on maintenance and assembly tasks of industrial machineries. The main skill involved in this kind of tasks is the procedural skill. Based on past literature a...
https://openalex.org/W4206602327
https://www.scielo.br/j/pci/a/T795Mfh4PLsBdxWvbMVRswj/?lang=pt&format=pdf
Portuguese
null
Do ocaso à revelação: uma breve análise do quadro de arranjo e dos instrumentos de pesquisa da Divisão de Censura de Diversões Públicas à luz da Arquivologia
Perspectivas em Ciência da Informação
2,021
cc-by
8,587
Do ocaso à revelação: uma breve análise do quadro de arranjo e dos instrumentos de pesquisa da Divisão de Censura de Diversões Públicas à Luz da Arquivologia Do ocaso à revelação: uma breve análise do quadro de arranjo e dos instrumentos de pesquisa da Divisão de Censura de Diversões Públicas à Luz da Arquivologia ...
https://openalex.org/W4249990614
https://ojs.unud.ac.id/index.php/beta/article/download/42466/26057
Indonesian
null
Analisis Teknis Penggunaan Sumber Daya Air Tanah Untuk Irigasi Tanaman Padi di Kabupaten Jembrana
BETA (Biosistem dan Teknik Pertanian)
2,018
cc-by
5,282
JURNAL BETA (BIOSISTEM DAN TEKNIK PERTANIAN Program Studi Teknik Pertanian, Fakultas Teknologi Pertanian Universitas Udayana http://ojs.unud.ac.id/index.php/beta Volume 6, Nomor 2, September 2018 JURNAL BETA (BIOSISTEM DAN TEKNIK PERTANIAN Program Studi Teknik Pertanian, Fakultas Teknologi Pertanian Universitas U...
https://openalex.org/W2899452182
https://europepmc.org/articles/pmc6211681?pdf=render
English
null
Measuring health of highway network configuration against dynamic Origin-Destination demand network using weighted complex network analysis
PloS one
2,018
cc-by
9,819
RESEARCH ARTICLE OPEN ACCESS Citation: Tak S, Kim S, Byon Y-J, Lee D, Yeo H (2018) Measuring health of highway network configuration against dynamic Origin-Destination demand network using weighted complex network analysis. PLoS ONE 13(11): e0206538. https://doi. org/10.1371/journal.pone.0206538 Editor: Sergio Go´mez, ...
https://openalex.org/W3165972032
https://link.springer.com/content/pdf/10.1007/s40619-021-00893-6.pdf
Italian
null
Approccio terapeutico non chirurgico al paziente con oftalmopatia basedowiana
˜L'œEndocrinologo
2,021
cc-by
1,794
L’Endocrinologo (2021) 22:103–105 https://doi.org/10.1007/s40619-021-00893-6 L’Endocrinologo (2021) 22:103–105 https://doi.org/10.1007/s40619-021-00893-6 TIROIDE TIROIDE  R. Le Moli lemoli.rosario@tiscali.it Introduzione L’OB si può prevenire controllando alcuni fattori di rischio [1]: L’oftalmopatia basedowiana (OB...
W2044282129.txt
https://wwwnc.cdc.gov/eid/article/9/12/pdfs/03-0270.pdf
en
Noninvasive Method for Monitoring<i>Pneumocystis carinii</i>Pneumonia
Emerging infectious diseases
2,003
cc-by
2,516
DISPATCHES Noninvasive Method for Monitoring Pneumocystis carinii Pneumonia Michael J. Linke,* Sandy Rebholz,† Margaret Collins,† Reiko Tanaka,† and Melanie T. Cushion*† The progression of Pneumocystis carinii pneumonia was temporally monitored and quantified by real-time polymerase chain reaction of P. carinii–specif...
https://openalex.org/W1932411203
https://revistacomsoc.pt/index.php/revistacomsoc/article/download/1135/1116
Portuguese
null
A liberdade académica e os seus inimigos
Comunicação e sociedade
2,015
cc-by
8,529
1 Já em 1989, Boaventura Sousa Santos (1994: 163-201) se referia à crise por que passava então a universidade e acentuava três aspetos: tratava-se de uma crise de hegemonia, de uma crise de legitimidade e de uma crise institucional. Porque a universidade não promovia já suficientemente a desejada mobilidade social, r...
https://openalex.org/W4388543076
https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/79/e3sconf_isffs2023_02038.pdf
English
null
New emerging viral disease on Giant Gourami (<i>Osphronemus goramy</i> Lac.) in Java, Indonesia
E3S web of conferences
2,023
cc-by
4,412
* Corresponding author: tauk001@brin.go.id © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/). New emerging viral disease on Giant Gourami (Osphronemus goramy Lac.) in Java,...
https://openalex.org/W4383557805
https://www.frontiersin.org/articles/10.3389/fphar.2023.1157229/pdf
English
null
Editorial: Herbal medicines for gastrointestinal and hepatic diseases - novel pharmacological and toxicological approaches, Volume I
Frontiers in pharmacology
2,023
cc-by
2,148
TYPE Editorial PUBLISHED 07 July 2023 DOI 10.3389/fphar.2023.1157229 TYPE Editorial PUBLISHED 07 July 2023 DOI 10.3389/fphar.2023.1157229 TYPE Editorial PUBLISHED 07 July 2023 DOI 10.3389/fphar.2023.1157229 Front. Pharmacol. 14:1157229. doi: 10.3389/fphar.2023.1157229 Front. Pharmacol. 14:1157229. doi: 10.3389/fphar.20...
https://openalex.org/W2941022421
https://www.journals.vu.lt/nonlinear-analysis/article/download/12885/11729
English
null
A new eigenvalue problem for the difference operator with nonlocal conditions
Nonlinear analysis
2,019
cc-by
10,259
eISSN: 2335-8963 ISSN: 1392-5113 eISSN: 2335-8963 ISSN: 1392-5113 https://doi.org/10.15388/NA.2019.3.9 Nonlinear Analysis: Modelling and Control, 2019, Vol. 24, No. 3, 462–484 Received: November 11, 2018 / Revised: March 7, 2019 / Published online: April 19, 2019 Abstract. In the paper, the spectrum structure of one-di...
https://openalex.org/W4376629786
https://www.nature.com/articles/s41598-023-34746-z.pdf
English
null
Transcutaneous auricular vagus nerve stimulation as a potential novel treatment for polycystic ovary syndrome
Scientific reports
2,023
cc-by
10,987
Transcutaneous auricular vagus nerve stimulation as a potential novel treatment for polycystic ovary syndrome Shike Zhang 1,2, Hui He 3*, Yu Wang 4, Xiao Wang 3 & Xiaofang Liu 5 OPEN Shike Zhang 1,2, Hui He 3*, Yu Wang 4, Xiao Wang 3 & Xiaofang Liu 5 Polycystic ovary syndrome (PCOS) is a common endocrine disorder in...
https://openalex.org/W2084203472
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000914&type=printable
English
null
Metagenomics of the Deep Mediterranean, a Warm Bathypelagic Habitat
PloS one
2,007
cc-by
12,149
INTRODUCTION microbes, thus sidestepping the need for culturing or isolation [5– 7]. Except for a few small-scale analyses of genome fragments from archaea and bacteria from mesopelagic waters [8–10], metage- nomic studies in the ocean have been also primarily devoted to surface waters (e.g. [11,12], including recent l...
https://openalex.org/W2744101564
http://www.scielo.br/pdf/sa/v74n6/0103-9016-sa-74-06-0469.pdf
English
null
Use of the software Seed Vigor Imaging System (SVIS®) for assessing vigor of carrot seeds
Scientia Agrícola
2,017
cc-by
4,214
469 469 Scientia Agricola Scientia Agricola http://dx.doi.org/10.1590/1678-992X-2016-0220 Scientia Agricola Introduction were conducted using this technique and successfully evaluated seed vigor, for crops such as soybean seeds (Hoffmaster et al., 2003), corn (Hoffmaster et al., 2005), melon (Marcos-Filho et al., 20...
https://openalex.org/W4396545456
https://link.springer.com/content/pdf/10.1007/s40544-023-0840-9.pdf
English
null
Core-rim structured MXene@SiO2 composites as oil-based additives for enhanced tribological properties
Friction
2,024
cc-by
7,908
Core-rim structured MXene@SiO2 composites as oil-based additives for enhanced tribological properties Yuhong CUI1, Shenghua XUE1, Tiantian WANG1, Shujuan LIU1, Qian YE1,*, Feng ZHOU1,2,*, Weimin LIU1,2 1 State Key Laboratory of Solidification Processing, Center of Advanced Lubrication and Seal Materials, School of Ma...
https://openalex.org/W3011698992
https://www.mdpi.com/2071-1050/12/6/2244/pdf
English
null
Consumers’ Perceptions and Attitudes toward Products Preventing Microfiber Pollution in Aquatic Environments as a Result of the Domestic Washing of Synthetic Clothes
Sustainability
2,020
cc-by
9,742
Article Article Received: 30 January 2020; Accepted: 11 March 2020; Published: 13 March 2020 Abstract: Microfibers released by synthetic clothes have a significant negative effect on the environment. Several solutions have been proposed and evaluated for their effectiveness, but studies have failed to address the human-cen...
https://openalex.org/W4236898557
https://www.qeios.com/read/CF6VXA/pdf
English
null
Congenital Spondylolysis, Lumbosacral Region
Definitions
2,020
cc-by
71
Open Peer Review on Qeios Open Peer Review on Qeios Congenital Spondylolysis, Lumbosacral R i National Cancer Institute National Cancer Institute Qeios ID: CF6VXA · https://doi.org/10.32388/CF6VXA Qeios · Definition, February 7, 2020 Source National Cancer Institute. Congenital Spondylolysis, Lumbosacral Region...
https://openalex.org/W3107582253
https://www.nature.com/articles/s41467-020-19771-0.pdf
English
null
High-resolution combinatorial patterning of functional nanoparticles
Nature communications
2,020
cc-by
8,347
ARTICLE Results Electric field-assisted patterning of NPs. The EFASP process is schematically illustrated in Fig. 1a. A charged nanopattern is first written on a fluorine polymer substrate (electret) by applying a localized high voltage (-40 to -90 V) using a conductive atomic force microscope (AFM) tip. Here, the localiz...
https://openalex.org/W2864095105
https://europepmc.org/articles/pmc6334715?pdf=render
English
null
A Web-Based Interactive Tool to Reduce Childhood Obesity Risk in Urban Minority Youth: Usability Testing Study
JMIR formative research
2,018
cc-by
15,438
A Web-Based Interactive Tool to Reduce Childhood Obesity Risk in Urban Minority Youth: Usability Testing Study Sandra Verdaguer1,2, MPH, MSc; Katrina F Mateo1,2, MPH; Katarzyna Wyka2, PhD; Tracy A Dennis-Tiwary3,4, PhD; May May Leung1, PhD, RDN 1School of Urban Public Health, Hunter College, The City University of New ...
W3020504136.txt
https://publications.muet.edu.pk/index.php/muetrj/article/download/1601/425
en
Estimating Sectoral Water Demand for Sindh Province of Pakistan
Mehran University research journal of engineering and technology
2,020
cc-by
5,063
Mehran University Research Journal of Engineering and Technology Vol. 39, No. 2, 398 - 406, April 2020 p-ISSN: 0254-7821, e-ISSN: 2413-7219 DOI: 10.22581/muet1982.2002.16 Estimating Sectoral Water Demand for Sindh Province of Pakistan Heman Das Lohano1 and Fateh Muhammad Marri2 RECEIVED ON 24.02.2019, ACCEPTED ON 30....
https://openalex.org/W1976416008
https://bmcneurosci.biomedcentral.com/counter/pdf/10.1186/1471-2202-10-105
English
null
Preliminary evidence that both blue and red light can induce alertness at night
BMC neuroscience
2,009
cc-by
9,300
BioMed Central BioMed Central Open Research article Preliminary evidence that both blue and red light can induce alertness at night Mariana G Figueiro*, Andrew Bierman, Barbara Plitnick and Mark S Rea * Corresponding author Received: 30 December 2008 Accepted: 27 August 2009 © 2009 Figueiro et al; licensee BioMed Cent...
W4391192875.txt
https://www.degruyter.com/document/doi/10.1515/9783839469125-034/pdf
de
8.3. Trutz: »[F]ür die Ewigkeit fixiert, festgehalten bis zum Tod«?
transcript Verlag eBooks
2,024
cc-by
18,417
232 Richard Slipp: Gedächtnis und Erzählen 8.3. Trutz: »[F]ür die Ewigkeit fixiert, festgehalten bis zum Tod«? »In much metafiction the reader is left with the impression that, since all fiction is a kind of parody of life, no matter how verisimilar it pretends to be, the most authentic and honest fiction might well ...
https://openalex.org/W2038737929
https://bmcneurosci.biomedcentral.com/counter/pdf/10.1186/1471-2202-14-S1-P360
English
null
Plasticity of network dynamics as observed experimentally requires heterogeneity of the network connectivity pattern
BMC neuroscience
2,013
cc-by
1,217
POSTER PRESENTATION POSTER PRESENTATION Huertas et al. BMC Neuroscience 2013, 14(Suppl 1):P360 http://www.biomedcentral.com/1471-2202/14/S1/P360 Open Access Open Access Plasticity of network dynamics as observed experimentally requires heterogeneity of the network connectivity pattern Marco A Huertas1, Marshall Hussa...
https://openalex.org/W3036525653
https://europepmc.org/articles/pmc7299996?pdf=render
English
null
Simulating dissolved 90Sr concentrations within a small catchment in the Chernobyl Exclusion Zone using a parametric hydrochemical model
Scientific reports
2,020
cc-by
6,554
Simulating dissolved 90Sr concentrations within a small catchment in the Chernobyl Exclusion Zone using a parametric hydrochemical model PEN Yasunori Igarashi   1 ✉, Yuichi Onda   2, Jim Smith   3, Sergey Obrizan4, Serhii Kirieiev5, Volodymyr Demianovych5, Gennady Laptev6, Dmitri Bugai7, Hlib Lisovyi6, Alexei Kono...
https://openalex.org/W4245575342
https://www.frontiersin.org/articles/10.3389/fped.2018.00421/pdf
English
null
Childhood Vasculitis
Frontiers in pediatrics
2,019
cc-by
8,375
Anja Schnabel 1* and Christian M. Hedrich 1,2,3* 1 Pädiatrische Rheumatologie, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Germany, 2 Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool...
https://openalex.org/W2917587079
https://europepmc.org/articles/pmc6387974?pdf=render
English
null
Live Single-Cell Metabolomics With Matrix-Free Laser/Desorption Ionization Mass Spectrometry to Address Microalgal Physiology
Frontiers in plant science
2,019
cc-by
7,077
ORIGINAL RESEARCH published: 18 February 2019 doi: 10.3389/fpls.2019.00172 Keywords: microalgae, single-cell metabolomics, live single cell mass spectrometry, matrix-free laser desorption/ionization-mass spectrometry, multivariate statistics, diatoms Coscinodiscus (Bacillariophyceae), chlorophyceae Haematococcus pluvia...
https://openalex.org/W2179235000
https://zenodo.org/records/899577/files/CheckList_article_17709.pdf
English
null
Reptilia, Squamata, Teiidae, Tupinambis longilineus: distribution extension
Check list
2,008
cc-by
1,123
Check List 4(3): 240–243, 2008. ISSN: 1809-127X Check List 4(3): 240–243, 2008. ISSN: 1809-127X Reptilia, Squamata, Teiidae, Tupinambis longilineus: Distribution extension. Ana Caroline de Lima Flávio Eduardo Pimenta Universidade Federal do Rio de Janeiro, Museu Nacional, Departamento de Vertebrados. Quinta da Boa Vi...
https://openalex.org/W3027355984
https://www.research-collection.ethz.ch/bitstream/20.500.11850/492418/2/chemistry-02-00030.pdf
English
null
On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C
Chemistry
2,020
cc-by
11,439
ETH Library Author(s): ( ) Edenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan; Díaz, José F.; Altmann, Karl-Heinz Received: 18 April 2020; Accepted: 21 May 2020; Published: 23 May 2020 p p y y Ab t t D hil C hi h i hi h Abstract: Deaza-epothilone C, which incorporates a thiophene moiety i...
https://openalex.org/W2485554478
https://research-information.bris.ac.uk/files/145380589/Full_text_PDF_final_published_version_.pdf
English
null
Is there a role for <scp>IGF</scp>‐1 in the development of second primary cancers?
Cancer medicine
2,016
cc-by
12,300
Shanmugalingam, T., Bosco, C., Ridley, A. J., & Van Hemelrijck, M. (2016). Is there a role for IGF-1 in the development of second primary cancers? Cancer Medicine, 5(11), 3353-3367. https://doi.org/10.1002/cam4.871 Publisher's PDF, also known as Version of record License (if available): CC BY Link to published version ...
https://openalex.org/W4294267611
https://www.nature.com/articles/s41598-022-17607-z.pdf
English
null
Phase-based fast 3D high-resolution quantitative T2 MRI in 7 T human brain imaging
Scientific reports
2,022
cc-by
12,233
OPEN Amir Seginer1 & Rita Schmidt  2,3* Magnetic resonance imaging (MRI) is a powerful and versatile technique that offers a range of physiological, diagnostic, structural, and functional measurements. One of the most widely used basic contrasts in MRI diagnostics is transverse relaxation time ­(T2)-weighted imaging,...
https://openalex.org/W2095216640
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032631&type=printable
English
null
Metabolic Control by S6 Kinases Depends on Dietary Lipids
PloS one
2,012
cc-by
8,506
Abstract Targeted deletion of S6 kinase (S6K) 1 in mice leads to higher energy expenditure and improved glucose metabolism. However, the molecular mechanisms controlling these effects remain to be fully elucidated. Here, we analyze the potential role of dietary lipids in regulating the mTORC1/S6K system. Analysis of S6...
https://openalex.org/W3114384164
https://europepmc.org/articles/pmc7823496?pdf=render
English
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Molecular Dynamics of Chloroplast Membranes Isolated from Wild-Type Barley and a Brassinosteroid-Deficient Mutant Acclimated to Low and High Temperatures
Biomolecules
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13,678
biomolecules   Received: 26 November 2020 Accepted: 23 December 2020 Published: 29 December 2020 Publisher’s Note: MDPI stays neu- tral with regard to jurisdictional clai- ms in published maps and institutio- nal affiliations. Keywords: brassinosteroids; chloroplast membranes; temperature stress; barley...
https://openalex.org/W2965910820
https://www.econstor.eu/bitstream/10419/196468/1/Article_2788.pdf
English
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Economic Modeling in the Management of Transition to Bioeconomy
Amfiteatru economic
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8,084
Provided in Cooperation with: The Bucharest University of Economic Studies Suggested Citation: Busu, Cristian; Busu, Mihail (2019) : Economic modeling in the management of transition to bioeconomy, Amfiteatru Economic Journal, ISSN 2247-9104, The Bucharest University of Economic Studies, Bucharest, Vol. 21, Iss. 50, pp...
https://openalex.org/W3201138321
https://europepmc.org/articles/pmc8448608?pdf=render
English
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Fabrication and Characterization of a Nanofast Cement for Dental Restorations
BioMed research international
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8,764
Research Article Fabrication and Characterization of a Nanofast Cement for Dental Restorations Kh. Yousefi,1 H. Danesh Manesh ,1 A. R. Khalifeh ,1 and A. Gholami 2 1Department of Materials Science and Engineering, School of Engineering, Shiraz University, 71348-51154 Shiraz, Iran 2Department of Pharmaceutical Biotechno...
https://openalex.org/W1988532023
https://nottingham-repository.worktribe.com/preview/1006596/Dawn-Marie_Walker--Classrom_Assessment.pdf
English
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Classroom Assessment Techniques: An Assessment and Student Evaluation Method
Creative education
2,012
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5,067
Creative Education 2012. Vol.3, Special Issue, 903-907 Published Online October 2012 in SciRes (http://www.SciRP.org/journal/ce) Creative Education 2012. Vol.3, Special Issue, 903-907 Published Online October 2012 in SciRes (http://www.SciRP.org/journal/ce) http://dx.doi.org/10.4236/ce.2012.326136 http://dx.doi.org...
https://openalex.org/W2511710684
https://orca.cardiff.ac.uk/id/eprint/89879/1/360SP.PDF
English
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International Ocean Discovery Program Expedition 360 Scientific Prospectus Southwest Indian Ridge Lower Crust and MohoThe nature of the lower crust and Moho at slower spreading ridges (SloMo-Leg 1)
Scientific prospectus
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International Ocean Discovery Program Expedition 360 Scientific Prospectus Southwest Indian Ridge Lower Crust and Moho The nature of the lower crust and Moho at slower spreading ridges (SloMo-Leg 1) Published by International Ocean Discovery Program Published by l O i Published by y International Ocean Discovery Progr...
https://openalex.org/W2053906245
https://scielo.isciii.es/pdf/azoo/v58n221/art5.pdf
Portuguese
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Influência da queima e aditivos químicos e bacterianos na composição química de silagens de cana-de-açúcar
Archivos de zootecnia
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cc-by-sa
6,813
Siqueira, G.R.1,2, R.A. Reis2, R.P. Schocken-Iturrino2, T.F. Bernardes2, A.J.V. Pires3, M.T.P. Roth2 e R.C. Amaral2 1Agência Paulista de Tecnologia dos Agronegócios (APTA). Pólo Regional de Desenvolvimento dos Agronegócios da Alta Mogiana. Av. Rui Barbosa, s/n. C.P. 35. CEP 14770-000 Colina-SP. Brasil. siqueiragr@aptar...
https://openalex.org/W3115845394
https://strathprints.strath.ac.uk/79271/7/Kolln_etal_JCS_2022_training_a_neural_network_to_selectively_restore_cellular_structures.pdf
English
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Label2label: Training a neural network to selectively restore cellular structures in fluorescence microscopy
bioRxiv (Cold Spring Harbor Laboratory)
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19,071
ABSTRACT Fluorescence microscopy is a commonly used technique in cell biology for determining the spatial distribution and abundance of target proteins in cells. It relies on the use of highly specific labels to visualise the cellular components of interest. Fluorescent labels can be chemical stains, antibody labelling...
https://openalex.org/W2138106523
https://atheneadigital.net/article/download/n18-flores-pons/720-pdf-ca
Catalan; Valencian
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Review of IC-Investigación Cualitativa blog
Athenea digital
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gemmaflorespons@gmail.com La producció i publicació de materials que fan referència a la metodologia qualitativa ha anat incrementant de forma inseparable a la seva consolidació com a metodologia de recerca en ciències socials. Internet ha tingut un paper rellevant en aquest sentit, ja que ha multiplica...
W4292566412.txt
https://www.frontiersin.org/articles/10.3389/fphy.2022.925523/pdf
en
Label-free observation of morphological alteration of irradiated-urothelial bladder carcinoma cells through digital holographic microscopy
Frontiers in physics
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5,281
Original Research 22 August 2022 10.3389/fphy.2022.925523 TYPE PUBLISHED DOI OPEN ACCESS EDITED BY Liangcai Cao, Tsinghua University, China REVIEWED BY Jun Ma, Nanjing University of Science and Technology, China Zhe Wang, Università degli Studi di Napoli Federico II, Italy *CORRESPONDENCE Hao Wang, wanghaobysy@bj...
https://openalex.org/W3127463742
https://www.granthaalayahpublication.org/journals/index.php/granthaalayah/article/download/IJRG15_S09_58/3023
English
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NEED OF GREEN GROWTH IN INDIA
International journal of research - granthaalayah
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985
NEED OF GREEN GROWTH IN INDIA Nancy Chauhan Govt. Girls P.G. College, Ujjain, (M.P.) The Economy of India is the seventh largest in the world by nominal GDP and the third largest by purchasing power parity with approximately 7% average growth rate for the last two decades. Although the years 2012-13 and 2013-14 have ...
W4224300629.txt
https://www.degruyter.com/document/doi/10.1515/bfp-2021-0093/pdf
de
Worüber schreiben LIS-Studierende ihre Abschlussarbeiten? Eine empirische Untersuchung der Jahre 2010–2019
Bibliothek
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BIBLIOTHEK – Forschung und Praxis 2022; 46(1): 216–226 Christiane Strauß* und Ulla Wimmer Worüber schreiben LIS-Studierende ihre Abschlussarbeiten? Eine empirische Untersuchung der Jahre 2010–2019 https://doi.org/10.1515/bfp-2021-0093 Zusammenfassung: Dieser Beitrag zur Themenwahl studentischer Abschlussarbeiten der...
https://openalex.org/W2040228980
https://www.scielo.br/j/spmj/a/HXnysWcyZtczznfYqcBSnwx/?lang=en&format=pdf
English
null
Twenty-first century: the beginning of the replacement parts era?
São Paulo medical journal
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1,185
Twenty-first century: the beginning of the replacement parts era? Século XXI: o início da era das peças de reposição? Alessandro Wasum MarianiI, Paulo Manuel Pêgo-FernandesII For many years, science fiction explored the idea of treating diseases by means of using artificial devices. References to replacement of human...
https://openalex.org/W2098060429
https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-015-0441-0
English
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Induction of tumor inhibitory anti-angiogenic response through immunization with interferon Gamma primed placental endothelial cells: ValloVax™
Journal of translational medicine
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8,192
* Correspondence: thomas.ichim@gmail.com †Equal contributors 1Batu Biologics Inc, San Diego, 9255 Towne Centre Drive, Suite 450, San Diego, CA 92121, USA Full list of author information is available at the end of the article RESEARCH Open Access Open Access Ichim et al. Journal of Translational Medicine (2015) 13:90 ...
https://openalex.org/W2950810015
https://zenodo.org/records/3257794/files/32608__1_203181_LE_311678.pdf
English
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A citation-based map of concepts in invasion biology
NeoBiota
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Martin Enders1,2,3, Frank Havemann4, Jonathan M. Jeschke1,2,3 1 Freie Universität Berlin, Department of Biology, Chemistry, Pharmacy, Institute of Biology, Königin-Luise- Str. 1–3, 14195 Berlin, Germany 2 Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB), Müggelseedamm 310, 12587 Berlin, Germany 3 Ber...
https://openalex.org/W3082251670
https://durham-repository.worktribe.com/preview/1258580/31654.pdf
English
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Control of Porphyrin Planarity and Aggregation by Covalent Capping: Bissilyloxy Porphyrin Silanes
Inorganic chemistry
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24,940
doi.org/10.26434/chemrxiv.12195084.v1 Control of Porphyrin Planarity and Aggregation by Covalent Capping: Bissilyloxy Porphyrin Silanes File list (2) download file view on ChemRxiv PorSil paper final.pdf (2.97 MiB) download file view on ChemRxiv PorSil SI final.pdf (18.18 MiB) Control of Porphyrin Planarity and Aggrega...
https://openalex.org/W4393604549
https://revistaincasciences.ingemmet.gob.pe/index.php/incasciences/article/download/32/28
es
Evidencias de tectónica transpresiva en la cordillera occidental del Centro del Perú (11° - 12°30’ S)
Deleted Journal
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3,494
Mamani & Jacay / Incasciences 1 (2): 34 - 44, 2023 doi:10.47347/incasciences.v1i2.32 Articulo Original Recibido: octubre 2023 Aceptado: noviembre 2023 INCASCIENCES Geociencias para el mundo Evidencias de tectónica transpresiva en la cordillera occidental del Centro del Perú (11° - 12°30’ S) Evidence of Transpressio...
W4392630179.txt
https://hal.science/hal-00632016/document
en
FERO: Finding extreme relativistic objects. I. Statistics of relativistic Fe K<SUB>alpha</SUB> lines in radio-quiet Type 1 AGN
null
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FERO: Finding extreme relativistic objects. I. Statistics of relativistic Fe Kalpha lines in radio-quiet Type 1 AGN I. de La Calle Pérez, A. L. Longinotti, M. Guainazzi, S. Bianchi, M. Dovciak, M. Cappi, G. Matt, G. Miniutti, P. O. Petrucci, E. Piconcelli, et al. To cite this version: I. de La Calle Pérez, A. L. Longi...
https://openalex.org/W2976775529
https://www.biorxiv.org/content/biorxiv/early/2019/09/30/787820.full.pdf
English
null
A secreted LysM effector protects fungal hyphae through chitin-dependent homodimer polymerization
bioRxiv (Cold Spring Harbor Laboratory)
2,019
cc-by
19,044
. CC-BY 4.0 International license available under a was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made The copyright holder for this preprint (which this version posted September 30, 2019. ; https://doi.org/10.1101/787820 doi: ...
https://openalex.org/W3122330867
https://scholarship.law.duke.edu/cgi/viewcontent.cgi?article=1552&context=faculty_scholarship
English
null
Foucault in Cyberspace: Surveillance, Sovereignty, and Hardwired Censors
Routledge eBooks
2,017
public-domain
18,170
* Copyright 1997 James Boyle, Professor of Law, Washington College of Law, American University. My remarks at the Symposium dealt more specifically with the law and policy of proposed changes to copyright on the Interet. However, I have already outlined some of those views in print, and at some length. S&eJAMES BOYLE, ...
https://openalex.org/W2803791743
http://periodicos.ufc.br/rene/article/download/32483/pdf/
English
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Social representations of imprisoned women on Acquired Immunodeficiency Syndrome
Rev Rene
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cc-by
4,786
1Universidade Federal da Paraíba. João Pessoa, PB, Brazil. DOI: 10.15253/2175-6783.2018193280 www.revistarene.ufc.br Original Article DOI: 10.15253/2175-6783.2018193280 www.revistarene.ufc.br Corresponding author: Tatyana Ataíde Melo de Pinho Corresponding author: Tatyana Ataíde Melo de Pinho Rua Hercílio Alves de Sou...
https://openalex.org/W2118619151
https://bmcmedicine.biomedcentral.com/counter/pdf/10.1186/1741-7015-7-66
English
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Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease
BMC medicine
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12,437
BioMed Central BioMed Central Open Acc Research article Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease Alessandra Pani1, Antonella Mandas2, Giacomo Diaz1, Claudia Abete1, Pier Luigi Cocco1, Fabrizio Angius...
https://openalex.org/W4376603037
https://www.revista.ueg.br/index.php/revelli/article/view/12961/9146
Portuguese
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O USO VARIÁVEL DO /R/ EM CODA EXTERNA
Revelli
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6,449
O USO VARIÁVEL DO /R/ EM CODA EXTERNA: CONTRIBUIÇÕES DA SOCIOLINGUÍSTICA APLICADA AO ENSINO THE VARIABLE USE OF THE /R/ IN EXTERNAL CODA: CONTRIBUTIONS OF APPLIED SOCIOLINGUISTICS TO TEACHING FREITAS, Rosely Lopes de FERREIRA, Jannaina Reis VIEIRA, Marília Resumo: O presente artigo, ancorado em uma perspectiva d...
https://openalex.org/W1904015299
https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/download/18219/pdf
English
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&lt;b&gt;Morphology and expression of genes related to skeletal muscle growth in juveniles of pirarucu (&lt;i&gt;Arapaima gigas&lt;/i&gt;, Arapaimatidae, Teleostei)&lt;/b&gt; - doi: 10.4025/actascianimsci.v35i3.18219
Acta Scientiarum. Animal Sciences
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Fernanda Regina Carani*, Bruno Oliveira Da Silva Duran, Tassiana Gutierrez De Paula, Warlen Pereira Piedade and Maeli Dal-Pai-Silva Fernanda Regina Carani*, Bruno Oliveira Da Silva Duran, Tassiana Gutierrez De Paula, Warlen Pereira Piedade and Maeli Dal-Pai-Silva Departamento de Morfologia, Instituto de Biociências, ...
https://openalex.org/W2143595798
https://www.frontiersin.org/articles/10.3389/fpsyg.2014.01581/pdf
English
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Collective screening tools for early identification of dyslexia
Frontiers in psychology
2,015
cc-by
15,174
INTRODUCTION has shown that inattention symptoms are associated with weak- nesses in naming speed and working memory (Shanahan et al., 2006; Lui and Tannock, 2007; Marzocchi et al., 2008; Arnett et al., 2012), especially working memory tasks requiring manipulation of information with a higher demand on the central exec...
https://openalex.org/W2096779532
https://www.e3s-conferences.org/10.1051/e3sconf/20130125006/pdf
English
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New low cost sorbents for Cr(VI) – batch and column experiments
E3S web of conferences
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cc-by
1,652
H. Šillerová1 and M. Komárek1 H. Šillerová1 and M. Komárek1 1 Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, 165 21, Prague 6, Czech Republic, sillerovah@fzp.czu.cz 1 Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, 165 21, Prague 6...
https://openalex.org/W3212363500
https://ph.pollub.pl/index.php/bia/article/download/817/2499
English
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Forgotten shelters of Kłodzko Land. On architecture inspired by the local building tradition
Budownictwo i Architektura
2,021
cc-by
6,687
Budownictwo i Architektura 20(3) 2021, 119-133 DOI: 10.35784/bud-arch.817 Received: 04.12.2019; Revised: 02.01.2020; Accepted: 20.10.2021; Available online: 29.10.2021 Orginal Article © 2021 Budownictwo i Architektura This is an open-access article distributed under the terms of the CC-BY-SA 4.0 Budownictwo i Archit...
https://openalex.org/W4361003748
https://www.scielo.br/j/mr/a/dJWG6wmhFWXqxcJ6FcJNjjg/?lang=en&format=pdf
English
null
Wear Behavior of Brass Based Composite Reinforced with SiC and Produced by Stir Casting Process
Materials research
2,023
cc-by
4,931
DOI: https://doi.org/10.1590/1980-5373-MR-2022-0196 Materials Research. 2023; 26: e20220196 Received: April 13, 2022; Revised: February 16, 2023; Accepted: March 01, 2023 The current investigation presents the wear-worn surface analysis of a silicon carbide-reinforced brass-based composite synthesized by stir casting....
https://openalex.org/W1538830058
https://pure.aber.ac.uk/portal/files/5947611/Duller_et_al_2015_JHE_85_111_125.pdf
English
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New investigations at Kalambo Falls, Zambia: Luminescence chronology, site formation, and archaeological significance
Journal of Human Evolution/Journal of human evolution
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cc-by
16,199
Aberystwyth University New investigations at Kalambo Falls, Zambia Duller, G. A. T.; Tooth, Stephen; Barham, Lawrence; Tsukamoto, Sumiko Citation for published version (APA): Duller, G. A. T., Tooth, S., Barham, L., & Tsukamoto, S. (2015). New investigations at Kalambo Falls, Zambia: Luminescence chronology, site forma...
https://openalex.org/W4390591206
https://www.intechopen.com/citation-pdf-url/88850
English
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Current Perspective on the Treatment of <i>Helicobacter pylori</i> Infection
IntechOpen eBooks
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6,496
Chapter Current Perspective on the Treatment of Helicobacter pylori Infection Malika Taufiq and Maliha Taufiq Abstract Helicobacter pylori (H. pylori) is a gram-negative aerobic bacteria that infects humans and is responsible for causing more than 80% of cases of chronic gastritis, peptic ulcer disease, and non-car...
https://openalex.org/W2327809899
https://eprints.glos.ac.uk/4565/1/Facet%20Theory%20and%20the%20mapping%20sentence.pdf
English
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Facet Theory and the Mapping Sentence As Hermeneutically Consistent Structured Meta-Ontology and Structured Meta-Mereology
Frontiers in psychology
2,016
cc-by
4,719
This is a peer-reviewed, final published version of the following document and is licensed under Creative Commons: Attribution 4.0 license: This is a peer-reviewed, final published version of the following document and is licensed under Creative Commons: Attribution 4.0 license: Hackett, Paul M ORCID: 0000-0002-9365-80...
https://openalex.org/W3094703244
https://opus.lib.uts.edu.au/bitstream/10453/145027/2/energies-13-05713-v2.pdf
English
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A Review of Energy Management Assessment Models for Industrial Energy Efficiency
Energies
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13,360
Received: 25 September 2020; Accepted: 29 October 2020; Published: 1 November 2020 Abstract: The necessity to ensure energy efficiency in the industries is of significant importance to attain reduction of energy consumption and greenhouse gases emissions. Energy management is one of the effective features that ensure energ...
https://openalex.org/W2956803025
http://ejournal.iba.ac.id/index.php/jemasi/article/download/11/11
Indonesian
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ANALISIS UKURAN PERUSAHAAN DAN PERTUMBUHAN ASET TERHADAP STRUKTUR MODAL PERBANKAN UMUM PEMERINTAH DI BURSA EFEK INDONESIA
Jemasi
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4,332
JEMASI Vol.13 No.2, Jul-Des 2017, hal. 182-196 JEMASI Vol.13 No.2, Jul-Des 2017, hal. 182-196 ABSTRACK This study aims to determine the effect of firms and asset growth on capital structure government general banking in Indonesia Stock Exchange. The problem in this research how to influence firm size and asset growth...
https://openalex.org/W2969469667
https://www.redalyc.org/journal/5606/560662202001/560662202001.pdf
English
null
Leadership Discourses of Keyae in Islamic Boarding School
Research, Society and Development
2,019
cc-by
7,306
Research, Society and Development ISSN: 2525-3409 ISSN: 2525-3409 rsd.articles@gmail.com Universidade Federal de Itajubá Brasil Research, Society and Development ISSN: 2525-3409 ISSN: 2525-3409 rsd.articles@gmail.com Universidade Federal de Itajubá Brasil Research, Society and Development ISSN: 2525-3409 ISSN: 2525-340...
https://openalex.org/W3154241601
https://www.frontiersin.org/articles/10.3389/fmicb.2021.647164/pdf
English
null
Rapidly Improving High Light and High Temperature Tolerances of Cyanobacterial Cell Factories Through the Convenient Introduction of an AtpA-C252F Mutation
Frontiers in microbiology
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cc-by
6,576
ORIGINAL RESEARCH published: 08 April 2021 doi: 10.3389/fmicb.2021.647164 Specialty section: Specialty section: This article was submitted to Microbiotechnology, a section of the journal Frontiers in Microbiology Keywords: cyanobacteria, Synechococcus elongatus PCC 7942, ATP synthase, sucrose, high temperature and high...
https://openalex.org/W4296953383
https://link.springer.com/content/pdf/10.1007/s10549-022-06726-w.pdf
English
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Clinical significance of the neutrophil-to-lymphocyte ratio in oligometastatic breast cancer
Breast cancer research and treatment
2,022
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5,976
Abstract Purpose  This study investigated the clinical impact of pretreatment neutrophil-to-lymphocyte ratio (NLR) on survival in patients with oligometastatic breast cancer. Patients and methods  We collected data from 397 patients who underwent primary breast surgery from 2004 to 2015 and developed recurrence durin...
https://openalex.org/W4253036086
https://refubium.fu-berlin.de/bitstream/fub188/38379/1/2021_Iqbal_etal.pdf
English
null
Predictors of parental mediation in teenagers’ internet use: A cross-sectional study of female caregivers in Lahore, Pakistan
Research Square (Research Square)
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cc-by
9,250
Open Access Predictors of parental mediation in teenagers’ internet use: a cross-sectional study of female caregivers in Lahore, Pakistan Sarosh Iqbal1, Rubeena Zakar2 and Florian Fischer3,4* Sarosh Iqbal1, Rubeena Zakar2 and Florian Fischer3,4* Abstract Background: The internet has become the most widely used medium a...
https://openalex.org/W4385550962
https://zenodo.org/records/8216917/files/BDJ_article_109082.pdf
English
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Vascular plant taxa occurrences in exotic woodland and in natural and production forests on the Islands of São Miguel, Terceira and Pico (Azores)
Biodiversity data jurnal
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cc-by
14,042
Biodiversity Data Journal 11: e109082 doi: 10.3897/BDJ.11.e109082 Data Paper Biodiversity Data Journal 11: e109082 doi: 10.3897/BDJ.11.e109082 Data Paper Biodiversity Data Journal 11: e109082 doi: 10.3897/BDJ.11.e109082 Data Paper Data Paper Vascular plant taxa occurrences in exotic woodland and in natural and prod...
https://openalex.org/W4241637694
https://clok.uclan.ac.uk/25922/1/25922%20Tyrer%20H%202014%20A%20murine%20Parasit%20Vectors.pdf
English
null
A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis
Parasites & vectors
2,014
cc-by
13,479
RESEARCH Open Access © 2014 Halliday et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the origin...
https://openalex.org/W3031138232
https://pure.bond.edu.au/ws/files/108337381/Partnering_ethics_and_chemistry.pdf
English
null
Partnering Ethics and Chemistry in Secondary and University STEM Education via an Innovatively Designed Periodic Table of Chemical Elements
Acta bioethica
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cc-by
3,264
Bond University Research Repository Partnering Ethics and Chemistry in Secondary and University STEM Education via an Innovatively Designed Periodic Table of Chemical Elements Bramstedt, Karina Published in: Acta Bioethica DOI: 10.4067/S1726-569X2020000100101 Licence: CC BY Link to output in Bond University research re...
https://openalex.org/W2167734792
https://www.cifor.org/publications/pdf_files/Articles/ACapistrano0601.pdf
English
null
Forest governance and institutional structure: an ignored dimension of community based forest management in the Philippines
International forestry review
2,006
cc-by
11,879
Gestion des forêts et structure institutionelle: une dimension peu connue de la gestion forestière communautaire aux Philippines Gestion des forêts et structure institutionelle: une dimension peu connue de la gestion forestière communautaire aux Philippines G. R. DAHAL et D. CAPISTRANO Cet article identifie les faibl...
https://openalex.org/W1224277973
https://zenodo.org/records/5553821/files/IJCHNV4N3A7-Domi%CC%81nguez.pdf
English
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Impact of School-Based Interventions on Children’s Healthful Nutritional Outcomes (2009-2013): Implications for Future Research
International journal of child health and nutrition
2,015
cc-by
10,798
*Address correspondence to this author at the Department of Psychology and Anthropology, Faculty of Nursing and Ocuppational Therapy, University of Extremadura Avda. de la Universidad s/n, 10003 Cáceres, Spain; Tel: 927257000/Ext. 51241; E-mail: prohlfsdomnguez@yahoo.es International Journal of Child Health and Nu...
https://openalex.org/W4391783390
https://link.springer.com/content/pdf/10.1007/s11356-024-32028-3.pdf
English
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Experimental strategy for the preparation of adsorbent materials from torrefied palm kernel shell oriented to CO2 capture
Environmental science and pollution research international
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cc-by
14,883
* Marlon Cordoba‑Ramirez mfcordoba@uniguajira.edu.co Abstract In this study, an experimental strategy to obtain biochar and activated carbon from torrefied palm kernel shell as an efficient material for ­CO2 removal was evaluated. Biochar was obtained by slow pyrolysis of palm kernel shell at different tempera- tu...
https://openalex.org/W4313830786
https://www.researchsquare.com/article/rs-1885399/latest.pdf
English
null
High Dose Intravenous Anakinra Treatment is Safe and Effective in Severe and Critical COVID-19 Patients: A Propensity Score Matched Study in a Single Center
Research Square (Research Square)
2,023
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High Dose Intravenous Anakinra Treatment is Safe and Effective in Severe and Critical COVID-19 Patients: A Propensity Score Matched Study in a Single Center High Dose Intravenous Anakinra Treatment is Safe and Effective in Severe and Critical COVID-19 Patients: A Propensity Score Matched Study in a Single Center MURAT ...
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Small satellite TT&amp;C allocations below 1 GHz: outcome of ITU WRC-19
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Abstract As hundreds of new small satellites are being launched each year, the RF spectrum for satellite communication becomes increasingly occupied. The International Telecommunication Union recognized this problem at World Radiocommunica- tion Conference 2015 (WRC-15) and invited study groups to investigate the util...
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https://lipidworld.biomedcentral.com/counter/pdf/10.1186/1476-511X-10-73
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Effects of n-3 PUFAs on breast cancer cells through their incorporation in plasma membrane
Lipids in health and disease
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© 2011 Corsetto et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ci...
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http://www.bioinformation.net/004/009800042010.pdf
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Classification of DNA sequences based on thermal melting profiles
Bioinformation
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Methodology: The first exon of the β -globin gene is often used as a standard example in many DNA-based graphing methods [32] is used as the first example. The gene family of β -globin varies between 86-105 bases and has a significant biological role in oxygen transport. β - globin gene across the 11 species is list...
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D2.1: Supply Chain Analysis and Requirements
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952690. D2.1 – Supply Chain Analysis and Requirements 952690 CYRENE PROJECT PARTNERS 4 31/05/2021 Table of Contents List of Tables .....................................................
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https://journalsojs3.fe.up.pt/index.php/jim/article/download/2183-0606_005.001_0005/270
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Efforts to build a culture of innovation in the Brazilian energy sector
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Journal of Innovation Management Cândido, Magro, Roczanski, Jamil JIM 5, 1 (2017) 40-57 HANDLE: http://hdl.handle.net/10216/103566 SM: Dec/2015 AM: Dec/ 2016 Efforts to build a culture of innovation in the Brazilian energy sector Ana Clara Cândido Professor at Federal University of Santa Catarina; Associated Re...
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Squamous cell carcinoma antigens (SCCAs) are sensitive biomarkers for atopic dermatitis in children and adolescents: a cross-sectional study
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Squamous cell carcinoma antigens (SCCAs) are sensitive biomarkers for atopic dermatitis in children and adolescents: a cross-sectional study Junya Hirayama  Mie University School of Medicine Takao Fujisawa  (  eosinophilosophy@gmail.com ) National Hospital Organization Mie National Hospital https://orcid.org/0000-000...
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Meta-analytical methods to identify who benefits most from treatments: daft, deluded, or deft approach?
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Meta-analytical methods to identify who benefits most from treatments: daft, deluded, or deft approach? These complications are often overlooked by reviewers. The issues are independent of other aspects of meta-analysis, such as the choice of one stage or two stage model fitting, or whether aggre- gate data or indi...
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The productive vocabulary of multimodal and unimodal English as a Foreign Language learners
Porta linguarum
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The productive vocabulary of multimodal and unimodal English as a foreign language learners Alejandra Montero-SaizAja Universidad de La Rioja Received: 30 May / Accepted: 7 January DOI: 10.30827/portalin.vi.21389 ISSN paper edition: 1697-7467, ISSN digital edition: 2695-8244 Received: 30 May / Accepted: 7 January D...
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https://www.rbciamb.com.br/Publicacoes_RBCIAMB/article/download/146/113
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Políticas públicas relacionadas ao transporte individual e coletivo e seus impactos sobre indicadores de saúde e ambiente em Uberlândia, Minas Gerais
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Endereço para correspondência: Endereço para correspondência: Boscolli Barbosa Pereira – Avenida João Naves de Ávila, 2121, Bloco 3E, Laboratório de Vigilância em Saúde Ambiental – Santa Mônica – 38400‑902 – Uberlândia (MG), Brasil – E‑mail: boscolli@ufu.br DOI: 10.5327/Z2176-947820160027 DOI: 10.5327/Z2176-94782...
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https://advancesindifferenceequations.springeropen.com/counter/pdf/10.1186/s13662-021-03429-2
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An accurate approach based on the orthonormal shifted discrete Legendre polynomials for variable-order fractional Sobolev equation
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© The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Co...
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Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution
PloS one
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Abstract Background: Polyamine biosynthetic pathway is a validated therapeutic target for large number of infectious diseases including cancer, giardiasis and African sleeping sickness, etc. a-Difluoromethylornithine (DFMO), a potent drug used for the treatment of African sleeping sickness is an irreversible inhibitor ...
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Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes
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Abstract Background: Excessive fat deposition is one of the largest problems faced by salmon aquaculture industries, leading to production losses due to high volume of adipose tissue offal. In addition, increased lipid accumulation may impose considerable stress on adipocytes leading to adipocyte activation and product...
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Treatment with pCramoll Alone and in Combination with Fluconazole Provides Therapeutic Benefits in C. gattii Infected Mice
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Treatment with pCramoll Alone and in Combination with Fluconazole Provides Therapeutic Benefits in C. gattii Infected Mice Jannyson J. Jandú 1, Marliete C. Costa 2, Julliana R. A. Santos 3, Fernanda M. Andrade 1, Thais F. Magalhães 2, Márcia V. Silva 1, Maria C. A. B. Castro 4, 5, Luanna C. B. B. Coelho 1, Aline G. Gome...
https://openalex.org/W1982566777
http://hal.in2p3.fr/in2p3-01093962/document
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Single-neutron orbits near 78 Ni: Spectroscopy of the<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>49</mml:mn></mml:math>isotope 79 Zn
Physics letters. B
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Single-neutron orbits near 78Ni: Spectroscopy of the N = 49 isotope 79Zn Box 35, FIN-40014 Jyväskylä, Finland q Institut für Kernphysik, Technische Universität Darmstadt, D-64289 Darmstadt, Germany r AB Department, CERN 1211, Geneva 23, Switzerland s IPHC, CNRS/IN2P3, Université de Strasbourg, F-67037 Strasbourg, Franc...
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https://www.scielo.br/j/jatm/a/NCrnkt8mCLszRwpLnmVh57r/?lang=en&format=pdf
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Modeling Resilience of Air Traffic Management Systems Based on Complex Networks
Journal of Aerospace Technology and Management
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ERROR: type should be string, got "https://doi.org/10.1590/jatm.v14.1273\nTHEMATIC SECTION | AVIATION SAFETY AND CONTINU https://doi.org/10.1590/jatm.v14.1273\nTHEMATIC SECTION | AVIATION SAFETY AND CONTINU ABSTRACT The air transport market has a strategic character, promotes economic and social development, and has a strong correlation \nwith the level of economic activity. The Air Traffic Management (ATM) system plays an essential role in air transportation and \ncan be characterized as a sociotechnical system that is too complex to research through classical approaches such as systems \nengineering. In this sense, the application of Complex Network Theory (CNT) analysis and modeling paradigms is driven by the \nneed to accommodate the growth of air traffic within an already saturated ATM infrastructure. The present work describes \nthe development of a resilience evaluation model of ATM systems based on CNT, its metrics and analysis tools. The model was \napplied to the Brazilian ATM system, demonstrating its usefulness in identifying the air traffic control (ATC) agencies that have the \ngreatest influence on the network. The results also showed that the Brazilian ATM network is resilient to random failures; however, \nit is particularly vulnerable to targeted attacks to the ATC agencies with the highest centrality. The research findings can be applied \nto prioritize the deployment of systems and equipment that enhance the resilience and operability of the Brazilian ATM system. Keywords: Air traffic management; ATM; Complex networks; CNT; Resilience. Modeling Resilience of Air Traffic \nManagement Systems Based on \nComplex Networks Gomes Sampaio1,* \n, Raimundo Nogueira Costa Filho2 \n, Marcelo Xavier Guterres1 Francisco Claudio Gomes Sampaio1,* \n, Raimundo Nogueira Costa Filho2 \n, Marcelo 1.Departamento de Ciência e Tecnologia Aeroespacial \n – Instituto Tecnológico de Aeronáutica – Divisão de Transporte Aéreo e \nAeroportos – São José dos Campos/SP, Brazil.2.Universidade Federal do Ceará \n – Departamento de Física – Fortaleza/CE, Brazil. *Correspondence author: claudiofcgs@hotmail.com J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 This is an open access article distributed under the terms of the Creative Commons license. Received: May 17, 2022 | Accepted: Aug 16, 2022\nPeer Review History: Single-Blind Peer Review.\nSection editor: Donizeti de Andrade INTRODUCTION In this line of reasoning, the characterization of the ATM as a complex system highlights the relevance of the application \nf C\nl\nN t\nk Th\n(CNT)\ni l b\nit\nid\nd li\nt\nl\nd\nl\ni t\nh i\nth t ll\ndi\ni This management strategy combines, in a strongly integrated way, the work of people with technical subsystems and operational \nprocedures in a complex system characterized by numerous simultaneous interactions between its various components, not being \npossible to fully understand through the study of its components individually, then adding its characteristics (Cook et al. 2015). h\ng\ngy\n,\ng y\ng\ny,\np\np\ny\np\nprocedures in a complex system characterized by numerous simultaneous interactions between its various components, not being \npossible to fully understand through the study of its components individually, then adding its characteristics (Cook et al. 2015). In this line of reasoning, the characterization of the ATM as a complex system highlights the relevance of the application \nof Complex Network Theory (CNT), mainly because it provides modeling tools and analysis techniques that allow discovering \nfundamental properties and suggest design guidelines to support high-performance nonlinear systems (Strogatz 2001).hfi In this line of reasoning, the characterization of the ATM as a complex system highlights the relevance of the application \nof Complex Network Theory (CNT), mainly because it provides modeling tools and analysis techniques that allow discovering \nfundamental properties and suggest design guidelines to support high-performance nonlinear systems (Strogatz 2001). Thus, questions arise that instigate critical thinking on the subject: Why is it relevant to model an air traffic system? How to \nmodel? How does a system react to eventual or intentional disturbances? How to measure the resilience of an ATM system? To help reflect on these issues, the present work can be characterized as an investigative approach to the CNT and the process \nof modeling ATM systems, more specifically as a study on the systematic application of a set of metrics of the CNT to measure \nthe resilience of an ATM system. Assuming that an air traffic system can be modeled and has its resilience measured based on the CNT, this work has the main \nobjective to develop a model for evaluating the resilience of ATM systems based on the concepts, metrics and analysis techniques \nof CNT applied to the Brazilian ATM network. INTRODUCTION This analysis model, in essence, is a major contribution of this research. The studies on the subject found in the literature are mainly directed to the structural analysis of the implemented airport \nnetwork (Zanin and Lillo 2013). The annual reports published by the National Civil Aviation Secretariat, for example, portray the \nreality of the Brazilian air transport with a reference centered on the volume of passengers and the cargo handled at the airports. The research is, therefore, limited to the analysis of interactions between flight operations and the ATM system, due to the \nlevel of complexity of air operations and the volumes of data to be processed to produce the appropriate results. The studies on the subject found in the literature are mainly directed to the structural analysis of the implemented airport \nnetwork (Zanin and Lillo 2013). The annual reports published by the National Civil Aviation Secretariat, for example, portray the \nreality of the Brazilian air transport with a reference centered on the volume of passengers and the cargo handled at the airports.hl reality of the Brazilian air transport with a reference centered on the volume of passengers and the cargo handled at the airports. The research is, therefore, limited to the analysis of interactions between flight operations and the ATM system, due to the \nlevel of complexity of air operations and the volumes of data to be processed to produce the appropriate results.fii The research is, therefore, limited to the analysis of interactions between flight operations and the ATM system, due to the \nlevel of complexity of air operations and the volumes of data to be processed to produce the appropriate results.fii For the Academy, air traffic modeling according to CNT metrics fills a gap in this area of knowledge. It is expected that the \nanalysis of air traffic networks, based on the air traffic control (ATC) agencies responsible for conducting air operations, will allow \nthe identification of the most important and central of the network, as well as the robustness, the reliability and resilience of the \nentire ATM system. The establishment of an analysis model also makes it possible to compare the characteristics and structural \nproperties of air traffic systems in different countries. INTRODUCTION The air transport market has a strategic character for countries, promotes economic and social development and is correlated \nwith the level of economic activity. With regard to passenger traffic, demand for air transport continues at its own pace, with \npositive growth rates. International travel and tourism, in particular, remain unstoppable and supported by the dynamics of the \nindustry, according to the prospective analysis of the Airports Council International. In the Brazilian market, government actions—such as the airport concessions program, the release of 100% of foreign capital \nparticipation in Brazilian companies, tax incentives aimed at reducing costs with aviation kerosene and positive signs for the \napproval of the open skies policy—implemented a project a favorable prospective scenario. In the view of Stefan et al. (2012), to understand an air transport system it is necessary to examine the interactions between the components \nthat make it up, including airlines, airports and, with special attention, Air Traffic Management (ATM), that comprises a sociotechnical system \nthat is too complex to be researched and improved through the use of classical approaches such as systems engineering and human factors. Received: May 17, 2022 | Accepted: Aug 16, 2022\nPeer Review History: Single-Blind Peer Review. Section editor: Donizeti de Andrade J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX\n2 Sampaio FCG, Costa Filho RN, Guterres MX The application of complexity science paradigms to the analysis and modeling of future operations is driven by the need to \naccommodate long-term air traffic growth within an already saturated ATM infrastructure (Blom and Bouarfa 2016).h The application of complexity science paradigms to the analysis and modeling of future operations is driven by the need to \naccommodate long-term air traffic growth within an already saturated ATM infrastructure (Blom and Bouarfa 2016).h This management strategy combines, in a strongly integrated way, the work of people with technical subsystems and operational \nprocedures in a complex system characterized by numerous simultaneous interactions between its various components, not being \npossible to fully understand through the study of its components individually, then adding its characteristics (Cook et al. 2015). INTRODUCTION The research results can be applied, eventually, in the prioritization process for the implementation of systems and equipment \nthat expand the operability of the ATC agencies, which would result, for example, in the expansion of the flight control capacity \nin the same portion of airspace; in the case of installation of radars; or increasing the probability of aircraft landing at an airport, \nby installing precision aids for aircraft approaches in adverse weather conditions. ATM RESILIENCE AND CNT This part of the work provides the technical basis, theoretical foundation, and a reflection on resilience in air traffic systems, \nall of them necessary to understand ATM systems, the CNT philosophy, and the real possibility of mapping non-linear systems \nthrough CNT metrics and their analysis techniques. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Air Traffic Management For Stefan et al. (2012), in a typical air transport system, air operations result from the dynamic interaction between airlines, \nairport operations and the ATM system, of which operational concept, according to the International Civil Aviation Organization \n(ICAO 2019), involves the dynamic and integrated management of traffic and airspace, including air traffic services (ATS), strategic \nmanagement of airspace and air traffic flow—with order, safety, regularity, economy and efficiency—by through the provision of \nfacilities and continuous services, involving air and ground facilities. In Brazil, activities involving the management and control of airspace are treated with strategic relevance and national security \ninterest, thus being entrusted to the Brazilian Air Force, with the Department of Airspace Control (DECEA) as the central J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks 3 organization of the Brazilian Airspace Control System. The Brazilian management model integrates civil ATC and military air \ndefense operations, which results in the rationalization of human and material resources, and optimizes the decision-making \ncycle in processes involving operational safety matters (DECEA 2019a). Airspaces can be understood as complex partitioned systems, primarily for purposes of organization, control, adequacy of \noperational capacity and protection against saturation of available ATC means. The classical ordering of airspace, according to the \nICAO (2005), involves the concept of Flight Information Region (FIR), which can be defined as a continuous volume of airspace, \ndelimited by duly established lateral and vertical limits, where ATS are provided. The FIRs are arranged contiguously and cover \nthe entire national territory. The Brazilian airspace is structured based on five FIRs associated with the respective control centers responsible for each of the \nregions (Fig. 1d). From this organization, it follows that the Amazonian (ACC-AZ), Recife (ACCRE), Brasília (ACC-BS), Curitiba \n(ACC-CW) and Atlantic (ACC-AO) control centers are responsible for the respective FIRs that bear their names: Amazonian FIR \n(SBAZ); Recife FIR (SBRE); Brasília FIR (SBBS); Curitiba FIR (SBCW); and, finally, the Atlantic FIR (SBAO).h The Brazilian airspace is structured based on five FIRs associated with the respective control centers responsible for each of the \nregions (Fig. 1d). Air Traffic Management From this organization, it follows that the Amazonian (ACC-AZ), Recife (ACCRE), Brasília (ACC-BS), Curitiba \n(ACC-CW) and Atlantic (ACC-AO) control centers are responsible for the respective FIRs that bear their names: Amazonian FIR \n(SBAZ); Recife FIR (SBRE); Brasília FIR (SBBS); Curitiba FIR (SBCW); and, finally, the Atlantic FIR (SBAO).h The airspace of an FIR is normally divided into smaller fractions called a sector, with the aim of facilitating management and \nexpanding its occupancy capacity for a greater number of flights. There are also other portions of airspace—smaller than an FIR \nand larger than a sector—destined for specific purposes and managed by specialized ATC agencies. Among these areas, some in \nwhich ATC services are provided are detailed below, characterizing them as controlled air spaces (DECEA 2013):fifi The airspace of an FIR is normally divided into smaller fractions called a sector, with the aim of facilitating management and \nexpanding its occupancy capacity for a greater number of flights. There are also other portions of airspace—smaller than an FIR \nand larger than a sector—destined for specific purposes and managed by specialized ATC agencies. Among these areas, some in \nwhich ATC services are provided are detailed below, characterizing them as controlled air spaces (DECEA 2013):fifi •\t ATZ – Aerodrome Traffic Zone (Fig. 1a) is an airspace established around an aerodrome for the protection of local air traffic \nof aircraft under visual flight rules. The Control Tower (TWR) is the ATC agency responsible for this type of airspace;tl •\t CTR – Control Zone (Fig. 1b) is a controlled airspace that aims to protect the trajectories of aircraft under instrument flight \nrules in departure or arrival procedures at one or more nearby aerodromes. The Approach Control (APP) is the ATC agency \nresponsible for this type of airspace; •\t TMA – Terminal Control Area (Fig. 1c) is a controlled airspace to which the air routes to the aerodromes contained in \nthis TMA converge. A TMA can be formed by several CTRs and ATZs, thus protecting the trajectory of the aircraft \nin procedures of arrival or departure from the aerodromes inserted in it. Air Traffic Management APP is also the agency responsible for this type \nof controlled airspace; •\t CTA – Control Area is a controlled airspace that contains the lower airways and the TMAs inserted in it, with the Area \nControl Center (ACC) as the control agency responsible for this type of airspace; •\t UTA – Superior Control Area is a controlled airspace similar to the CTA, differing in that it contains the superior airways and \nother parts of the superior airspace, defined as superior control areas. The ACC is the ATC agency responsible for this type \nof airspace. •\t UTA – Superior Control Area is a controlled airspace similar to the CTA, differing in that it contains the superior airways and \nother parts of the superior airspace, defined as superior control areas. The ACC is the ATC agency responsible for this type \nof airspace. Source: Adapted from DECEA (2019a) and Bastos and Baum (2009). Figure 1. Airspaces and ATC agencies: (a) Aerodrome Traffic Zone (ATZ); (b) Control Zone (CTR); (c) Terminal \nControl Area (TMA); and (d) Flight Information Regions (FIRs) and their respectively Area Control Centers (ACCs). Source: Adapted from DECEA (2019a) and Bastos and Baum (2009). Source: Adapted from DECEA (2019a) and Bastos and Baum (2009). Figure 1. Airspaces and ATC agencies: (a) Aerodrome Traffic Zone (ATZ); (b) Control Zone (CTR); (c) Terminal \nControl Area (TMA); and (d) Flight Information Regions (FIRs) and their respectively Area Control Centers (ACCs). J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX\n4 Sampaio FCG, Costa Filho RN, Guterres MX Complementing the set of ATC/ATS agencies, there is the Aerodrome Flight Information Service (AFIS), which is an air traffic \nservice provided to all aircraft operating in the movement area and in flight in the lower airspace, within a radius of 27 nm (50 km), \naround approved aerodromes that do not have a TWR. AFIS is carried out by an aeronautical telecommunications station, which \nprovides meteorological and coordination information for the safety and efficiency of air operations. Complex Network Theory The origins of the CNT, according to Anderson (1972), are related to studies in the field of statistical physics, the dynamics of \nnonlinear systems and information theory, and can be conceptualized as the multidisciplinary study of complex systems. In this \nsense, air transport, in general, and ATM can be analyzed and studied through these powerful tools available (Cook et al. 2015). Using CNT, a network can be modeled and represented by a set of nodes, connected to each other by a set of links. The connections \nbetween the nodes can also be defined as directed, nondirected, with nodes of the same type or of different types, weighted and, \nstill, of dynamic behavior, when there is variation of the structural elements of the network, nodes, and links, in time function \n(Zanin and Lillo 2013). As a practical example of this modeling system (that can be seen in Fig. 2), an air transport network can be formed by airports \n(nodes), linked by flights from one node to another (directed connection) and weighted based on the number of passengers. If the \nflights have information about the proposed departure time and duration, the network can be dynamically analyzed with respect \nto time. Another example of structuring could be observed in a representative network of airspace sectors or navigation points \nsuch as nodes, connected by flights (edges) that cross those sectors or fly over these navigation points. These types of network organization facilitate ATC modeling (Cai et al. 2012) and, by analyzing centrality metrics, allow \nidentifying potential traffic bottlenecks. The detection of communities in these types of networks has proved to be an effective \ninstrument to rationalize airspace restructuring based on traffic analysis (Gurtner et al. 2014). Source: Adapted from Newman (2003). Figure 2. Examples of complex networks: (a) network formed by 8 nodes and 10 edges; (b) directed network, \ni\nhi h\nh d\nh\nifi di\ni\n( )\ndi\nd\nk\ni h\nl\nd\nd Source: Adapted from Newman (2003). re 2. Examples of complex networks: (a) network formed by 8 nodes and 10 edges; (b) directed network\ni\nhi h\nh d\nh\nifi di\nti\n( )\ndi\nt d\nt\nk\nith\nl\nd t\nd Figure 2. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Complex Network Theory Examples of complex networks: (a) network formed by 8 nodes and 10 edges; (b) directed network, edge has a specific direction; (c) nondirected network with only one \none edge type; and (d) network with weighted nodes and edges. In the understanding of Cook et al. (2015) and Sallan and Lordan (2020), metrics are measured with properly established \ncalculation systems that allow understanding or characterizing a network; identify its organization; its critical nodes; and the \nbehaviors that emerge from the dynamic relationships and interactions between its components. A summary of the CNT metrics that characterize the structure of a network is detailed below, based on the works of Albert \nand Barabási (2002) and Newman (2003). J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks The shortest path between two nodes l (m, n) is defined as the path with the fewest intermediate nodes between the origin \nand the destination. Since L is the set of shortest paths and |L| is the number of shortest paths in the network, the average shortest \npath in the network R, l(R) can be defined through Eq. 1. \b\n(1) \b (1) (1) According to Freeman (1979), betweenness centrality represents the control capacity that intermediate nodes have over \nother nodes that locally depend on this intermediary to connect, that is, it is the relationship between the shortest paths that pass \nthrough the node n and the shortest paths between all pairs of nodes. Let N be the set of network nodes, σ(m,o) be the number of \nshortest paths between nodes m and o, and σ(m,o) (n) the number of these paths that cross the node n, the betweenness centrality \nof a node n, β(n), can be calculated by Eq. 2. This metric makes it possible to assess the proportion of a given node of a network \nas a necessary link between different groups belonging to the same network, based on the shortest possible path. \b\n(2) (2) Proximity centrality represents how close a node is to the other nodes in the network that it can reach. Being π(m, n) the length \nof the shortest path between a node m and any other reachable node n, the proximity centrality γ(m) can be defined by means \nof Eq. 3. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Complex Network Theory Broadly speaking, the analysis of this metric makes it possible to understand how a node is perceived as the center of \nthe network; to what extent does it employ the help of intermediate nodes to reach more distant ones; and how it positions itself \n(dependent/independent) regarding the structure of the network. \b\n(3) (3) The clustering coefficient can be conceptualized as the degree to which the nodes of a network tend to cluster. In practical \nterms, it represents a measure of the density of edges between the neighbors of a node, that is, if the neighbors are directly \nconnected—number of triangles in the network. It is also known as the network transitivity measure. Equation 4 proposes the \nformula for calculating the clustering coefficient C of a network N. Here, emo represents the edges that connect neighboring nodes \nto node n; vm and vo represent the vertices neighboring to node n; Rn defines the neighboring graph to node n; and kn represents \nthe number of neighbors of vertex n. \b\n(4) (4) Equation 5 defines the density D of a network as the ratio between the number of edges |ϵ| and the total number of possible \nedges of the complete network, where |ν| is the number of the nodes. The analysis of this metric allows an understanding of the \ncohesion of a network, because the higher the density, the more cohesive it will be (Nooy et al. 2005). Equation 5 defines the density D of a network as the ratio between the number of edges |ϵ| and the total number of possible \nedges of the complete network, where |ν| is the number of the nodes. The analysis of this metric allows an understanding of the \ncohesion of a network, because the higher the density, the more cohesive it will be (Nooy et al. 2005). \b\n(5) (5) The diameter d of a network R can be defined as the longest shortest path between any pair of nodes in the network and can \nbe calculated by Eq. 6. The analysis of this metric allows the understanding of the dispersion of the network. \b\n(6) (6) The degree of a node corresponds to the total number of links connected to it and can be divided into in-degree and out-\ndegree. The in-degree of a node n, kin(n), represents the total number of links that arrive at this node. The out-degree, kout(n), J. Aerosp. Complex Network Theory Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX describes the total number of connections that leave the node. Thus, the degree of a node n is equivalent to the total number of \nlinks that arrive or leave the node: k(n) = kin(n) + kout(n). In this reasoning, the average degree k of a network R (Eq. 7) is the result \nof the relation between the sum of the degrees of nodes in the network and the total number of nodes |N|, where N is the set of \nnodes in the network. In the case of weighted networks, the strength of a node is defined as the sum of the weights of the node \nconnections, whether input or output. describes the total number of connections that leave the node. Thus, the degree of a node n is equivalent to the total number of \nlinks that arrive or leave the node: k(n) = kin(n) + kout(n). In this reasoning, the average degree k of a network R (Eq. 7) is the result \nof the relation between the sum of the degrees of nodes in the network and the total number of nodes |N|, where N is the set of \nnodes in the network. In the case of weighted networks, the strength of a node is defined as the sum of the weights of the node \nconnections, whether input or output. \b\n(7) (7) (7) Based on several studies on this metric, Barabási (2009) identified a specific type of network that he conceptualized as \nscale-free network. This conception is mainly supported by studies by Barrat et al. (2004) and Guimerà et al. (2005), which \nshowed that the probability that the degree (or strength) of a node k is greater than x can be characterized by the power law \nP (k > x) = Nx−g e−ax, where 1 ≤ g ≤ 2 is the tail exponent, a is the parameter that controls the speed of exponential decay and \nN a normalization constant. As a network with random distribution increases in size, the relationship between nodes with \nhigh degrees and other nodes in the network decays. In a scale-free network, however, this relationship remains constant as a \nfunction of the size of the network. Resilience Air traffic management is an example of a complex sociotechnical system, which encompasses interactions between different \norganizations, technical systems, operational units, regulatory agencies, and consumers (DeLaurentis and Ayyalasomayajula 2009). In this extremely specialized field, technology plays a prominent role and the value of studying ATM resilience is perceived as \nrelevant due to the studies of several researchers, especially Hollnagel et al. (2006). Routinely, the air traffic network coexists with different types of internal and external disturbances, which daily test its resilience. These disturbances can interact with each other, enhancing their cascading effects, which can extend over different scales of time \nand space. According to Eurocontrol (2009), the management of disturbances in air traffic systems involves adjustments and \nadaptations in the processes of their subsystems, which result from their inherent complexities, enhanced by the finite human \nand material resources available in the operational control agencies. In the Brazilian ATM activities, minor disturbances are managed by control agencies distributed throughout the country, \nwhile disturbances that may have global reach in the network are handled by a collegiate decision-making process, with \nrepresentatives of airlines, airport administrators and ATM agencies. Flights are rerouted, or timed, to allow for more effective \naccommodation of system-wide disturbances. As an example, in the case of airspace congestion, supervisors of control agencies \ncan coordinate with airlines to redirect or adjust their flight schedules. In these cases, safety and fluidity are prioritized at \nthe expense of the economy, managing conflicting interests that need to be conveniently resolved without generating major \ninconveniences for passengers.fii Despite the coordinated work, there are times when the resilience of the air traffic system cannot contain significant delays in \nflights, which can even spread through the network and compromise several control areas and airports for an extended period. Effects caused by bad weather are classic examples of this type of behavior. In addition to more common cases with restricted \nconsequences, there are other atypical cases with very serious consequences. The two cases can be classified into two broad \ncategories, those that produce effects that strongly affect the performance of the system; and catastrophic accidents involving a \nsingle aircraft or a group of them. The examples described in the previous paragraphs highlight a wide range of events with profound consequences. However, due \nto the resilience of ATM systems, the vast majority of these potential disturbances generate effects that go unnoticed by the users \nof the system. Complex Network Theory The analysis of the average degree metric—strength for weighted networks—allows the identification of the most active and \ninfluential nodes in the network, since they have a higher number of links and, consequently, higher values of k(n). For weighted \nnetworks, the strength of a node can also be properly correlated with the number of flights and passengers passing through this \nnode (Barrat et al. 2004; Guimerà et al. 2005). J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Resilience Analysis Model We developed a model to assess the resilience of ATM systems based on complex networks, in which the system under analysis \nis represented by a directed graph G (A, F) with the ATC/ATS agencies (A, nodes) connected by fractions of the managed flights \n(F, links) in which ATM control and services are effectively performed. We simulated network operations under disturbances and assess resilience in direct and random attack scenarios, \nremoving nodes from the core and using a new metric created by us, the resilience index (Ire), which measures the level of \nresilience comparing interconnections between the ATC/ATS agencies of the initial ATM system and the resulting one after \nthe disturbance simulation. Resilience Index Real world networks represent systems that are constantly modified by the removal or addition of new components, involving \nthe establishment of new connections which are influenced by the degree distribution of the network nodes. In the case of the \nATC/ATS system, new agencies can be activated to support growing air activities in a region of operational interest, normally \nassociated with a significant increase in air movements or the entry into operation of a new airport. The resilience of a network is a property that is related to the distribution of degrees, to connectivity—the existence of \nlinks between vertices—and, mainly, to the removal of nodes from this network. Normally, the loss of nodes results in a \nprogressive reduction in the operational capacity of the network, so its resilience can be measured by removing its nodes, \nwith different criteria for the removal process, either randomly or directed to the nodes that have higher degree or centrality \n(Newman 2003). Considering that the coordination between ATC/ATS agencies for the management and transfer of flights control by adjacent \nagencies depends on the effective connection between them, then the vertices of the largest component formed after removing a \nnode n of the network still maintain, among themselves, a significant coordination capacity in relation to the original network.l In this line of thought, the resilience index reflects the reduction of the ATM network operational capacity with the unavailability \n(removal) of a specific ATC/ATS agency, that is, an index of 0.11 means the loss of 11% of the network’s operational capacity. In short, the lower the resilience index, the greater the resilience of the network. Resilience Despite this, according to Zanin and Lillo (2013), little effort has been devoted to understanding the relationships J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks between the topology of ATM networks and their vulnerabilities. As, in essence, complexity stems from the interaction between \nvarious subsystems, CNT modeling tools that focus on interactions are better suited to capture the phenomenon of resilience, \nwhich has greater adherence to the approach of sociotechnical systems rather than technical systems. The value of the CNT for investigating the impact of disturbances on a sociotechnical system, in general terms, can be \nestablished based on the capacities to absorb them, adapt to them, and restore its operational performance to pre-disturbance \nlevels (Francis and Bekera 2014).if Absorptive capacity is defined as the extent to which a system can absorb disturbances and minimize their effects. Incorporating \nan additional time in advance into the effective duration of flights is a proactive action to accommodate delays that increases \nabsorption capacity. The ability of a system to accommodate to disturbances by modifying its internal processes is defined as \nadaptive capacity, which differs from absorption capacity in that an adaptive system can change its reaction. Restorative capacity \nrefers to the power that a system has to recover from disturbances and restore or improve its operational capacity, based on the \nlevel of performance presented before the disturbing event. Based on these concepts, a system that has only the ability to absorb disturbances is characterized as robust, while a system that \nhas both absorption and restoration capabilities is said to be reliable. Therefore, resilience can be characterized as the attribute of \na system capable of absorbing, adapting, and recovering from disturbances. This highlights the need to prioritize the development \nof adaptive capacity to increase the resilience of a system. Resilience Analysis Model Thus, being N the set of nodes of an ATM network, we can define a resilience index, IRe(n), of the network in relation to the \nloss of a node, n, using the percentage number of nodes of the largest component that remains connected, that is the fraction \nbetween the number of vertices of the largest component of the network that remains connected after the removal of this node, \n|SN−{n}|, and the total number of vertices of the network before the start of the disturbance (|N|) (Eq. 8). Thus, J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX \b\n(8) (8) Model Development J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Model Development Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks SBEG)—will result in five transfers of control records in the ATM flights file: (TWR-FZ, APP-WZ); (APP-WZ, ACC-RE); (ACC-RE, \nACC-AZ); (ACC-AZ, APP-WN); (APP-WN, TWR-EG). For the network modeling (M2 process) the dataset formed by the two files generated in P 1.1 and P 1.2 is used. It starts with \nimporting the dataset into the Gephi workbench, with special attention to the type of graph to be selected (directed) and the \nmerge strategy for edges (sum), therefore, for flights with similar origin and destination, the system will create only one origin/\ndestination edge with weight equal to the sum of the occurrences of parallel edges in the ATM file. The following CNT metrics used in the model, along with the resilience index (Ire, Eq. 8) have their use justified by the \nability to characterize a network and identify its organization, robustness, reliability, and resilience: average shortest path (Eq. 1); \nbetweenness centrality (Eq. 2); proximity centrality (Eq. 3); clustering coefficient (Eq. 4); density (Eq. 5); diameter (Eq. 6); and \naverage degree (Eq. 7). For the statistical treatment and graphic visualization of the dataset that serves as the basis for the modeling of the complex \nstructured network, the interactive free software platform Gephi version 0.9.2 (Bastian et al. 2009) is used. Metric calculations \n(P 2.1 process) are performed using the tools available in the Statistics Tab, selecting each of the metrics of interest. Calculation results \nare automatically entered into fields in the graph nodes file. In order to measure the resilience of the network (module M3), the results obtained through the statistical calculations, summarized \nin the metrics file (A 2.1), are analyzed regarding the maintenance of the minimum operational capacity of the network, which \nincludes the verification of the operability of the system in terms of absorption, accommodation, and response to disturbances, \nthrough the evaluation of updated metrics generated at each iteration. This step is terminated when the minimum operational \ncapacity of the network is verified, which occurs when the number of vertices of the largest component of the network that remains \ninterconnected after the removal of a node is less than 50% of the number of nodes in the undisturbed network (|S| < 0.5). RESULTS AND DISCUSSION This section details the results and describes the discussions carried out with the application of the resilience analysis model \nto the Brazilian ATM system. The subsections that compose it are structured with a focus on the results achieved, specifying \nthe general characteristics of the network (General Analysis), deepening research on the resilience of the Brazilian ATM system \n(Resilience Analysis), identifying the communities present in the structure (Community Analysis), and evaluating the weekly \ndistribution of flights in relation to days and times (Dynamics Analysis). Model Development As long as the network remains operational, the most central ATC/ATS agencies are removed from the network (process P 3.1), \none at a time, and the calculation of the statistics is iteratively reworked, up to the point where the network loses its operational \ncapacity (|S| < 0.5), when then, the process is terminated. During this process, the metrics file (A 2.1) is indexed based on the \nbetweenness centrality and the most central node in the network—the ATC/ATS agency with the highest centrality value—has all \nits links excluded, that is, all flights referring to that node are eliminated from the graph. The flow is directed to a new statistical \ncalculation (P 2.1) with generation of a new set of metrics. The process of discussing the results (module M4) involves, in a generic way, the identification of the general characteristics of \nthe ATM network based on the calculated metrics; the assessment of established communities, which makes it possible to understand \nthe dependencies between control agencies; understanding of dynamic behavior over time; and the analysis of resilience, which \nultimately reflects the system’s ability to maintain its operability in situations of degradation. Model Development p\nThe flowchart shown in Fig. 3 consolidates the proposed resilience analysis model. The modules and processes used in the \nmodel, which appear in the flowchart, are detailed below. The flowchart shown in Fig. 3 consolidates the proposed resilience analysis model. The modules and processes used in the \nmodel, which appear in the flowchart, are detailed below. Source: Elaborated by the authors. Figure 3. Representative flowchart of the Resilience Analysis Model of ATM Systems Based on Complex Networks. Source: Elaborated by the authors. y\nFigure 3. Representative flowchart of the Resilience Analysis Model of ATM Systems Based on Complex Networks. y\nFigure 3. Representative flowchart of the Resilience Analysis Model of ATM Systems Based on Comp y\nFigure 3. Representative flowchart of the Resilience Analysis Model of ATM Systems Based on Complex Networks. presentative flowchart of the Resilience Analysis Model of ATM Systems Based on Complex Networks. The M1 module is responsible for generating the dataset of the analysis model, consisting of the processes that generate the ATC/\nATS file (P 1.1) and the ATM flight file that can be managed (P 1.2). Process P 1.1 generates the file of control and ATS agencies,\nbased on the information obtained through research carried out in the Internet Aisweb portal (DECEA 2019b) and in Chapter 5 of\nROTAER (DECEA 2019c). The P 1.2 process aims to create the ATM flights file, which correspond to the manageable fractions of the\noriginal flights file (ANAC 2019). For each of the records in the National Civil Aviation Agency (ANAC) flights file, the shortest route\nbetween the origin and destination airports is established, which makes it possible to identify, based on the analysis of this route in the\nrespective Aeronautical Route Chart (DECEA 2019b), all ATC/ATS agencies that will be responsible for managing the entire flight. As an example, during a flight from Fortaleza International Airport (SBFZ) to Manaus International Airport (SBEG), the aircraft \nreceives ATC service from six different ATC agencies, one at a time: Fortaleza Tower (TWR-FZ), Fortaleza Approach Control \n(APP-WZ), Recife Area Control Center (ACC-RE), Amazonian Area Control Center (ACC-AZ), Manaus Approach Control (APP-WN) \nand Eduardo Gomes Tower (TWR-EG). Transfers of control occur within the limits of operational responsibility between two \nadjacent ATC agencies. In this example, processing one single record in the file of active scheduled flights (ANAC 2019)—(SBFZ, J. Aerosp. Technol. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 General Analysis The Brazilian air traffic network was modeled having as nodes the ATC/ATS agencies (146), linked by fractions of flights \n(17,347) in which ATM, control and services are effectively performed. Figure 4 visually presents the weekly distribution of \nscheduled flights in Brazil, registered with ANAC on August 12, 2019, with a focus on the ATC and service agencies that exert \nthe greatest influence on the network Brazilian airline. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX 10 Source: Elaborated by the authors. Figure 4. Brazilian ATM network: weekly distribution of scheduled flights, highlight for the most \ninfluential ATC/ATS agencies classified by the volume of managed air movements. Source: Elaborated by the authors. Source: Elaborated by the authors. re 4. Brazilian ATM network: weekly distribution of scheduled flights, highlight for the most li yl\ng\ng\ng\ninfluential ATC/ATS agencies classified by the volume of managed air movements. yl\ng\ng\ng\ninfluential ATC/ATS agencies classified by the volume of managed air movements. Table 1 summarizes the global metrics of the network, where “Connected ATC/ATS agencies” represents the ability of an \nagency to connect to other agencies in the network, with values ranging from 0% (no connection possible) to 100% (all agencies \ncan connect to each other directly or via intermediary agencies); “Average clustering coefficient” represents a measure of the \ndensity of connections between adjacent agencies; “Average managed flights” expresses the average number of flights managed by \neach of the agencies in the network; “Average shortest path” translates the average of all paths connecting an origin agency to any \ndestination agency, with the fewest passes through other intermediary agencies; “Average degree” is the result of the ratio between \nthe sum of the degrees of all agencies (the total number of direct connections, links arriving or leaving each agency) and the total \nnumber of agencies in the network; “Diameter” is defined as the longest of the shortest paths between any pair of agencies in the \nnetwork; and finally “Density”, which is defined as the ratio of the number of flights transferred by all ATC agencies to the total \nnumber of possible transfers of flights across the entire network. Table 1. Brazilian ATM network: global metrics and parameters. Table 1. Brazilian ATM network: global metrics and parameters. In a comprehensive way, the degree of network nodes follows a power law, revealing the joint existence of a few operational \nATC agencies that manage many flights and many agencies that provide ATS to a few aircraft in flight. In this way, the \nBrazilian air traffic network can be characterized as a scale-free network. Far from being just an abstract classification, J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 General Analysis As for cohesion, that is, how close to having direct connections between all its vertices, the air traffic network has a low \ndensity (1.5%), reflecting the existing hierarchy in the Brazilian airspace control system with few direct connections between \nthe ATC/ATS agencies. Regarding the dispersion of the network—with reference to the definition of unitary distance as the one that separates two \ndirectly connected vertices—the flights that most need ATM involve the participation of seven ATC/ATS agencies with six transfers \nof control (network diameter). Regarding the dispersion of the network—with reference to the definition of unitary distance as the one that separates two \ndirectly connected vertices—the flights that most need ATM involve the participation of seven ATC/ATS agencies with six transfers \nof control (network diameter). The Brazilian network is also characterized by a low level of redundancy in the connections between the control agencies, since, \naccording to the metrics obtained, the average of clustering coefficients shows that each ATC/ATS unit has only 5.3% chance of \nbeing connected to a neighboring control on this network. In practice, however, this is not entirely correct to say, as the ACCs and some of the larger APPs (e.g., São Paulo and Rio de \nJaneiro) are subdivided into operational sectors, each operating as an independent ATC agency, that is, there is internal redundancy \nin these operational units, but it is not perceived by the calculated metrics due to the structuring of the dataset used in the modeling. It is also possible to connect the TWRs directly with the ACCs, in the event of an APP failure. The general characteristics of the Brazilian air traffic network, identified in this initial analysis, can be explained by the hierarchy \nof the structure of the control agencies in spatially restricted areas, since, in a situation of operational normality, the TWRs are \nconnected to the ACCs through the APPs. In situations of operational degradation of approach control, however, a TWR can \nbe linked directly to the ACC responsible for the FIR where it operates. Regarding the AFIS, the connection with the ACCs is \ncarried out directly. This differentiation is justified by the complexity of ATC compared to the flight information service provided by AFIS. Control agencies are responsible for controlled airspaces with a high volume of air traffic, while agencies that provide ATS are \nresponsible for uncontrolled airspaces, normally with low flight traffic. General Analysis Metric / Parameter\nValue\nATC/ATS agencies connected \n100%\nAverage clustering coefficient \n5.3%\nAverage managed flights \n407 managed flights\nAverage shortest path \n3.272 flight transfers\nAverage degree \n2.171 direct connections\nDiameter \n6 flight transfers\nDensity \n1.5%\nSource: Elaborated by the authors. Table 1. Brazilian ATM network: global metrics and parameters. Metric / Parameter\nValue\nATC/ATS agencies connected \n100%\nAverage clustering coefficient \n5.3%\nAverage managed flights \n407 managed flights\nAverage shortest path \n3.272 flight transfers\nAverage degree \n2.171 direct connections\nDiameter \n6 flight transfers\nDensity \n1.5%\nSource: Elaborated by the authors. Table 1. Brazilian ATM network: global metrics and parameters. In a comprehensive way, the degree of network nodes follows a power law, revealing the joint existence of a few operational \nATC agencies that manage many flights and many agencies that provide ATS to a few aircraft in flight. In this way, the \nBrazilian air traffic network can be characterized as a scale-free network. Far from being just an abstract classification, J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks identifying the type of network resulting from modeling a real air traffic system provides relevant information to rationalize \nit and mitigate its vulnerabilities. It is known from studies by Albert et al. (2000) that scale-free networks are intensely resilient to random failures, since \nthe vast majority of nodes have a small number of connections. Removing nodes of this type, therefore, would not affect \nthe overall functionality of the network too much. In the opposite direction, however, scale-free networks are particularly \nvulnerable to attacks targeting the most central and influential nodes in the network. Sun and Wandelt (2021) reinforce these \nideas by analyzing the different impacts of attacks, concluding that targeted attacks are more harmful to ATM systems than \nrandom failures. Regarding the connectivity of the Brazilian air traffic network, the graph generated by the modeling is fully connected, \nforming a single large component (Fig. 4), showing that it is possible to reach all operational ATC agencies from any of them. However, connectivity between control agencies is low, since each ATC/ATS agency is directly linked, on average, to 2.171 of \nthem, about 1.5% of the total operational agencies. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 General Analysis Turning to the quantitative analysis of the results, the Table 2 expresses the classification of Brazilian ATC/ATS agencies in \nrelation to relevance in the national network, based on the volume of air movements managed in a period of one week, betweenness \ncentrality and proximity centrality, respectively. While betweenness centrality allows assessing the ability of a given node to present \nitself as a necessary link for the connection between groups in the network, proximity centrality helps in the perception of which \nATC/ATS agencies are responsible for the initial management of flights with the lowest number of control transfers. The two \nmetrics together show the most relevant ATC agencies. The data presented show that the São Paulo approach control (APP-XP) concentrates the largest volume of managed air \nmovements (17,662), even surpassing all ACC. This result comes from the direct connection of this APP with three of the busiest \nTWRs in Brazil: Guarulhos (TWR-GR) with 4,336 movements; Congonhas (TWR-SP) with 2,964; and Campinas (TWR-KP) \nwith 1,514 weekly movements controlled. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX 12 Table 2. The 10 most relevant ATC/ATS agencies classified by number of flights managed \nduring a week of operation, betweenness centrality and proximity centrality. Rank \nFlights managed \nBetweenness centrality \nProximity centrality\n1\n17,662 APP São Paulo\n0.5499 ACC Curitiba\n0.52 ACC Curitiba\n2\n14,911 ACC Curitiba\n0.4538 ACC Amazonian\n0.49 ACC Amazonian\n3\n13,051 ACC Brasília\n0.3339 ACC Recife\n0.48 ACC Brasília\n4\n8,428 ACC Recife\n0.3030 ACC Brasília\n0.48 ACC Recife\n5\n6,236 APP Rio de Janeiro\n0.0680 APP São Paulo\n0.41 ACC Atlantic\n6\n4,336 TWR Guarulhos\n0.0410 APP Rio de Janeiro\n0.37 APP São Paulo\n7\n3,855 ACC Amazonian\n0.0275 APP Belo Horizonte\n0.35 APP Vitória\n8\n3,824 APP Brasília\n0.0275 APP Recife\n0.35 APP Rio de Janeiro\n9\n3,004 APP Belo Horizonte\n0.0275 APP Londrina\n0.34 APP Curitiba\n10\n2,964 TWR São Paulo\n0.0275 APP Bauru\n0.34 APP Florianópolis\nSource: Elaborated by the authors. Table 2. The 10 most relevant ATC/ATS agencies classified by number of flights managed \nduring a week of operation, betweenness centrality and proximity centrality. Table 2. The 10 most relevant ATC/ATS agencies classified by number of flights managed \nduring a week of operation, betweenness centrality and proximity centrality. General Analysis Likewise, the approach control of Rio de Janeiro (APP-WJ) ranks significantly in fifth place with 6,236 controlled flights, behind \nonly the approach control of São Paulo and the Curitiba, Brasília, and Recife ACCs. With an operational structure similar to that \nused in São Paulo, the APP-WJ manages the air flow of the TWRs at Santos Dumont (TWR-RJ) and Galeão (TWR-GL) airports. The establishment of these two regions of intense movement can be understood by the correlation of air traffic with economic \nactivity in the two largest Brazilian cities in terms of population and gross domestic product, resulting in the creation of the air \nbridge between Rio de Janeiro and São Paulo, one of the busiest routes around the world. Also noteworthy are the results of the approach control and the control tower in Brasília (APP-WR and TWRBR) with, \nrespectively, 3,824 and 1,917 movements, demonstrating the relevance of the federal capital in the Brazilian air network. Also noteworthy are the results of the approach control and the control tower in Brasília (APP-WR and TWRBR) with, \nrespectively, 3,824 and 1,917 movements, demonstrating the relevance of the federal capital in the Brazilian air network. Once again, the hierarchy of the ATC structure of the Brazilian network can be used to justify the results of centrality obtained, \nsince the ACCs are responsible for liaising with the APPs and with the AFIS at isolated aerodromes in their areas of operational \nresponsibility. The APPs act in the same way, intermediating the links between TWRs and ACCs. Once again, the hierarchy of the ATC structure of the Brazilian network can be used to justify the results of centrality obtained, \nsince the ACCs are responsible for liaising with the APPs and with the AFIS at isolated aerodromes in their areas of operational \nresponsibility. The APPs act in the same way, intermediating the links between TWRs and ACCs. Thus, the results presented are coherent, classifying the ACC in the first positions, followed by the APP. The TWR and AFIS, \nin the opposite direction, have the lowest centrality values, since they are positioned at the ends of the network. Thus, the results presented are coherent, classifying the ACC in the first positions, followed by the APP. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 General Analysis ATC/ATS agencies removed\n0\n1\n2\n3\n4\n5\n6\n7\n8\n9\n10\nATC/ATS agencies disconnected\n–\n106\n49\n118\n23\n18\n24\n15\n16\n10\n4\nFlights removed\n0\n20\n265\n12\n992\n1,504 916\n1,790 1,514 2,964 7,534\nFlights on the network (%)\n100.00 99.98 99.78 99.99 99.17 98.74 99.23 98.50 98.73 97.52 93,69\nLargest comp. – Qty of nodes connected (%)\n100.00 99.32 98.63 97.95 96.58 95.89 94.52 93.15 92.47 91.78 77,40\nConnec. ATC/ATS agencies groups\n1\n2\n3\n4\n6\n7\n9\n11\n12\n13\n28\nLargest connected ATC/ATS agency – comps. 146\n145\n144\n143\n141\n140\n138\n136\n135\n134\n113\nAverage managed flights\n407\n407\n407\n407\n400\n390\n383\n371\n361\n340\n289\nAverage degree\n2.171\n2.130 2.103 2.089 2.055 2.041 2.014 1.979 1.966 1.952 1.664\nDensity\n0.015\n0.015 0.015 0.014 0.014 0.014 0.014 0.014 0.014 0.014 0.011\nDiameter\n6\n6\n6\n6\n6\n6\n6\n6\n6\n6\n6\nAverage shortest ATC/ATS path\n3.272\n3.281 3.284 3.288 3.284 3.276 3.268 3.260 3.254 3.248 3.188\nSource: Elaborated by the authors. Table 3. Resilience analysis: random failures. In the opposite direction, however, the removal of a node with a high degree of distribution or centrality—targeted attack on a \ncritical node identified, according to Sun and Wandelt (2021)—usually has a devastating effect on the operational capacity of the \nnetwork, as can be seen in Table 4, which show the results obtained by the selective removal of ATC/ATS agencies with a higher \ndegree of betweenness centrality. The interdiction of the Curitiba ACC, the ATC agency with the highest degree of centrality in \nthe network, causes an immediate loss of 31% of network operability (IRe = 0.31). It is still possible to assess the resilience of the network in situations of simultaneous unavailability of ATC/ATS units. Checking the column corresponding to ACC-AZ in Table 4, it appears that the removal of ACC-CW and ACC-AZ together \nreduces the operational capacity of the network to 44.52%, that is, resilience index (IRe = 0.55). Finally, it is proved that the Brazilian ATM network presents a behavior similar to that of scale-free networks, being strongly resistant \nto random failures, but with a relevant loss of its operational capacity in situations of attacks directed at its most relevant ATC agencies. Table 4. Resilience analysis: targeted attacks. General Analysis The TWR and AFIS, \nin the opposite direction, have the lowest centrality values, since they are positioned at the ends of the network.ii Specifically in relation to the betweenness centrality, the classification of APPs is supported by direct connections with more \nthan one TWR/AFIS in their respective areas of operational responsibility and in the volume of managed flights. Resilience Analysis Specifically in relation to the betweenness centrality, the classification of APPs is supported by direct connections with more \nthan one TWR/AFIS in their respective areas of operational responsibility and in the volume of managed flights. Specifically in relation to the betweenness centrality, the classification of APPs is supported by direct connections with more \nthan one TWR/AFIS in their respective areas of operational responsibility and in the volume of managed flights. Resilience Analysis The resilience analysis of air traffic systems is relevant due to the need to know and understand the impacts caused on the functionality \nof the network in cases of unavailability of ATC agencies, especially the ACCs, which act as intermediaries in flights from different FIRs, \nlinking the APPs and connecting isolated AFIS. Air traffic systems have occasional failures in equipment and subsystems, but they \nrarely lead to loss of global network functionality. This stability is normally attributed to the redundant links present in its structure. In general, scale-free networks are little affected when their nodes are randomly removed, that is, this type of network has \nstrong resilience to undirected node loss. In the case of the Brazilian air traffic network, such behavior can be understood by the \npredominance of ATC/ATS agencies with a low number of managed flights, so the impact on the global operability of the network \nby the loss of this type of agency is not significant. The results recorded in Table 3 prove that the random removal of ATC/ATS agencies from the Brazilian network has a reduced \neffect on its operability, because even after the simultaneous unavailability (removal) of 10, the network resilience index remained \nat IRe = 1 − 77.40 / 100 = 0.226, where 77.40 is the is the percentage number of nodes connected in the largest component after \nthe random removal of 10 ATC/ATS agencies. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Modeling Resilience of Air Traffic Management Systems Based on Complex Networks Table 3. Resilience analysis: random failures. Metric / Parameter description\nValues\nN. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 General Analysis Metric / Parameter description \nValues\nATC/ATS agency removed\nComplete Network\nACC-CW\nACC-AZ\nACC-BS\nTotal number of ATC/ATS agencies removed\n0\n1\n2\n3\nFlights removed\n0\n14,911\n3,855\n13,051\nFlights on the network (%)\n100.00\n87.51\n84.28\n73.34\nLargest component – Qty of nodes connected (%)\n100.00\n69.18\n44.52\n20.55\nConnected ATC/ATS agencies groups\n1\n30\n58\n76\nLargest connected ATC/ATS agency – comps. 146\n101\n65\n30\nAverage managed flights\n407\n307\n279\n208\nAverage degree\n2.171\n1.644\n1.205\n0.945\nDensity\n0.015\n0.011\n0.008\n0.007\nDiameter\n6\n5\n5\n4\nAverage shortest ATC/ATS path\n3.272\n3.207\n3.115\n2.451\nSource: Elaborated by the authors. Table 4. Resilience analysis: targeted attacks. Table 4. Resilience analysis: targeted attacks. Table 4. Resilience analysis: targeted attacks. Sampaio FCG, Costa Filho RN, Guterres MX J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Community Analysish The analysis of communities allows the understanding of the relationships of dependence between air traffic agencies, whether \nstructural, organizational, or even economic, when carefully observing the areas of operational responsibility where these control \nagencies provide their specialized services. It is also possible to infer knowledge about the commercial interests of airlines, through \na critical look at the concentration of flights originating in or destined for a specific control area. Figure 5 depicts the Brazilian air \ntraffic network with the ATC/ATS agencies grouped into five identified communities, of which identification process was carried \nout using the Newman–Girvan algorithm. Source: Elaborated by the authors. Source: Elaborated by the authors. Figure 5. Brazilian ATM network: ATC/ATS agencies grouped into communities, by color, Figure 5. Brazilian ATM network: ATC/ATS agencies grouped into communities, by color, l Figure 5. Brazilian ATM network: ATC/ATS agencies grouped into communities, by color, \nwith the size of the nodes proportional to the volume of flights managed. with the size of the nodes proportional to the volume of flights managed. In general, these communities reflect the influence exerted by the ACC in their respective areas of operational responsibility, \nbeing approximately equivalent to the FIR in geographic terms. Thus, the region covered by the green community, for example, \nshows the Amazonian FIR; the light blue community reflects the distribution of FIR Recife’s control agencies; the orange one \ncovers the Brasília FIR; and the purple-colored community overlaps the Curitiba FIR. The exceptions are the dark blue community—which shows the influence of São Paulo APP, with Guarulhos, Congonhas, \nCampinas and São José dos Campos control towers—and the Atlantic ACC—located in the upper flights between Brazil and \nEurope, which has connections only with Amazonian, Recife, and Curitiba ACCs, absorbed by the Recife ACC community. CONCLUSION We developed a resilience analysis model of ATM systems based on complex networks and applied it to the Brazilian ATM \nnetwork. For that, we also gathered and integrated different data sources to build the complex network representation of the \nanalyzed system and, by using metrics and analysis techniques from CNT, evaluated the characteristics and resilience level of it. We developed a resilience analysis model of ATM systems based on complex networks and applied it to the Brazilian ATM \nnetwork. For that, we also gathered and integrated different data sources to build the complex network representation of the \nanalyzed system and, by using metrics and analysis techniques from CNT, evaluated the characteristics and resilience level of it. The Brazilian air traffic network is a scale-free network, that is, there are few control agencies that manage a large number \nof flights and many agencies that provide ATS to a few aircraft. Therefore, the Brazilian network is resilient to random failures; \nhowever, it is particularly vulnerable to targeted attacks to the nodes with the highest centrality.h The Brazilian air traffic network is a scale-free network, that is, there are few control agencies that manage a large number \nof flights and many agencies that provide ATS to a few aircraft. Therefore, the Brazilian network is resilient to random failures; \nhowever, it is particularly vulnerable to targeted attacks to the nodes with the highest centrality. The graph generated by the modeling is fully connected, demonstrating that it is possible to reach all operational ATC agencies \nfrom any of them. The network is also not very cohesive, with a low density (0.015), reflecting the existence of few direct links \nbetween the ATC/ATS agencies. The average shortest path is low (3.272), meaning that few transfers of control, three to four on \naverage, are required when managing flights in Brazilian airspace. The characteristics identified in the Brazilian air traffic network \ncan be explained by the hierarchy of the structure of control agencies in spatially restricted areas and justified by the complexity \nof the ATC system. From the quantitative analysis of the air movements managed by ATC/ATS agencies, the results prove that the area control \ncenters play a prominent role in the national context, however, the approach control of São Paulo (APPXP) concentrates the \nlargest volume of air movements (17,662), surpassing all area control centers in the country. Dynamics Analysis The results of the previous analysis are based on fixed information in relation to time, not reaching the effects caused by the \nduration of the flights, their distribution throughout the day or even on different days of the week. In this sense, in order to better \nunderstand these impacts on the Brazilian air traffic system, it is necessary to investigate the network metrics referenced in days \nand times when flights occur. Table 5 consolidates the information on the air movements of the Brazilian network, during the period of one week. The data \nis totaled by day of the week, divided into 4–6-h intervals. From the data analysis, it appears that the daily cycle of ATM has a \npractically constant volume of flights from Tuesday to Friday, regarding the daily total of movements. Mondays are the busiest \ndays of the week, as opposed to Saturdays and Sundays when air activity is reduced. With regard to the daily distribution of flights, \nTable 5 allows the inference that air activity is significantly intensified in the afternoon and at night on week-days. The movements, \nespecially the low air traffic on Saturday and Sunday, are not explained by the resilience analysis model, but may be related to \nexternal factors not evaluated in this study—whether financial or operational by the airlines - exceeding the scope of this research. Modeling Resilience of Air Traffic Management Systems Based on Complex Networks 15 Table 5. Brazilian ATM network: Dynamics analysis. Day of the week\n00–06 UTC\n06–12 UTC\n12–18 UTC\n18–00 UTC\nDaily subtotal\nSunday\n1,090\n2,169\n4,297\n4,994\n12,550\nMonday\n3,874\n4,332\n6,376\n6,545\n21,126\nTuesday\n3,194\n3,563\n5,249\n5,344\n17,349\nWednesday\n3,109\n3,891\n5,924\n6,071\n18,995\nThursday\n3,135\n3,768\n5,697\n5,979\n18,579\nFriday\n3,178\n3,858\n5,914\n5,800\n18,750\nSaturday\n3,146\n2,913\n3,224\n2,739\n12,023\nSource: Elaborated by the authors. Table 5. Brazilian ATM network: Dynamics analysis. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 CONCLUSION This expressive result comes from \nthe direct connection of this APP with three control towers with significant air movement in the country: Guarulhos (TWR-GR) \nwith 4,336 movements; Congonhas (TWR-SP) with 2,964; and Campinas (TWR-KP) with 1,514 controlled weekly movements. With an operational structure similar to the one used in São Paulo, the Rio de Janeiro approach control (APPWJ), which manages \nthe airflow from the control towers at Santos Dumont (TWR-RJ) and Galeão (TWR-GL) airports, it ranks significantly in fifth place \nwith 6,236 air movements, behind only the approach control of São Paulo and the control centers of Curitiba, Brasília, and Recife. The existence of these two regions of intense flight movement, established between the terminal control areas of São Paulo \nand Rio de Janeiro, can be understood by the correlation of air traffic with economic activity in the two largest Brazilian cities \nin population and economic terms, the which results in one of the busiest routes in the world, the Rio-São Paulo aerial bridge. The analysis of communities makes it possible to understand the dependency relationships between air traffic agencies. In general, the distribution of communities in the Brazilian air traffic network reflects the influence exerted by the control centers \nin their respective areas of operational responsibility, being approximately equivalent to the FIR in geographic terms. Thus, five \nlarge communities were identified with ATC/ATS agencies distributed, grouped, along the Amazonian, Recife, Brasília, and \nCuritiba FIRs, and a fifth highlighted community, which portrays the influence of the approach control of São Paulo and of its \nbusy control towers in Guarulhos, Congonhas and Campinas. J. Aerosp. Technol. Manag., São José dos Campos, v14, e2222, 2022 Sampaio FCG, Costa Filho RN, Guterres MX\n16 Sampaio FCG, Costa Filho RN, Guterres MX Regarding the dynamic analysis of data on the daily cycle of ATM, the results show that the volume of flights has a small \nvariation from Tuesday to Friday, regarding the daily movement total. Mondays are the days with the most air traffic during the \nweek—21,126 movements—as opposed to Saturdays and Sundays, when air activity is the least. As for the variation of movements \nduring the day, the air activity intensifies considerably in the afternoon and night periods, with the highest average movement \nclose to 6,000 in the night period from Monday to Friday. CONCLUSION The practical results that may come from the analysis of air traffic systems through modeling tools that employ the CNT showed \nhigh potential to identify bottlenecks in the networks, expand operational capabilities and raise the levels of operational safety of the air \noperations. Thus, there are great opportunities for future research in this area of knowledge, and some of the following can be glimpsed: \nto model and analyze an ATM system taking into account the sectorization of airspace under the responsibility of the ACC and APP, \ntreating each sector as an independent operational ATC agency; and to structure the network nodes based on the navigation points \nof the air routes, in order to identify bottlenecks in the airways, with the purpose of rationalizing the design of the airspace structure. Studies on complex networks have developed rapidly in recent years, as shown by the significant attention of scientists from \ndifferent areas to the field of complex systems, signaling the relevance of this knowledge area for the Academy and for society. 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Proposal for Integrated Management of Verticillium Wilt Disease in Avocado Cultivar Hass Crops
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agronomy Article Proposal for Integrated Management of Verticillium Wilt Disease in Avocado Cultivar Hass Crops Joaquín Guillermo Ramírez-Gil 1, * 1 2 *   Citation: Ramírez-Gil, J.G.; Morales-Osorio, J.G. Proposal for Integrated Management of Verticillium Wilt Disease in Avocado Cultivar Hass Crops...