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23247298 Chirality recognition of the protonated serine dimer and octamer by infrared multiphoton dissociation spectroscopy. Infrared multiphoton dissociation (IRMPD) spectroscopy has been used to record IR signatures of chirality recognition in the protonated serine dimer and octamer in the 3200-3800 cm(-1) region. Th... |
23247504 Sophorolipids-functionalized iron oxide nanoparticles. Functional iron oxide nanoparticles (NP) have been synthesized in a one and a two-step method using a natural functional glycolipid belonging to the family of sophorolipids (SL). These compounds, whose open acidic form is highly suitable for nanoparticle s... |
23247824 Nicotinic receptors in addiction pathways. Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that consist of pentameric combinations of α and β subunits. These receptors are widely distributed throughout the brain and are highly expressed in addiction circuitry. The role of nACh... |
23248173 TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation. Protection and restoration of a functional β-cell mass are fundamental strategies for prevention and treatment of diabetes. Consequently, knowledge of signals that determine the functional β-cell... |
23248191 Impact of restricted maternal weight gain on fetal growth and perinatal morbidity in obese women with type 2 diabetes. OBJECTIVE Since January 2008, obese women with type 2 diabetes were advised to gain 0-5 kg during pregnancy. The aim with this study was to evaluate fetal growth and perinatal morbidity in rel... |
23248196 Statins and Risk of Diabetes: An analysis of electronic medical records to evaluate possible bias due to differential survival. OBJECTIVE Two meta-analyses of randomized trials of statins found increased risk of type 2 diabetes. One possible explanation is bias due to differential survival when patients who ar... |
23248236 Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione. Increasing antibiotic resistance makes the identification of new antibacterial principles an urgent task. The thioredoxin system including thioredoxin reductase (TrxR), thioredoxin (Trx), and NADPH pl... |
23249181 Progress of pharmacological studies on alkaloids from Apocynaceae. Alkaloid was a kind of biological active ingredient. There were various types of alkaloids in Apocynaceae. This paper reviewed the progress on alkaloids from Apocynaceae, which contained origin, structure, and pharmacological activity. |
23249244 Multifaceted ultrafast intramolecular charge transfer dynamics of 4-(dimethylamino)benzonitrile (DMABN). Intramolecular charge transfer (ICT) of DMABN has been the subject of extensive investigations. Through the measurements of highly time-resolved fluorescence spectra (TRFS) over the whole emission region, w... |
23249338 Light-harvesting and ultrafast energy migration in porphyrin-based metal-organic frameworks. Given that energy (exciton) migration in natural photosynthesis primarily occurs in highly ordered porphyrin-like pigments (chlorophylls), equally highly ordered porphyrin-based metal-organic frameworks (MOFs) might be... |
23249341 Interaction of OH radicals with Arizona Test Dust: uptake and products. Kinetics and products of the interaction of OH radicals with solid films of Arizona Test Dust (ATD) were studied using a low pressure flow reactor (0.5-3 Torr) combined with a modulated molecular beam mass spectrometer for monitoring of th... |
23249525 Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit. This study investigated whether the serotonin 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) can induce compulsive checking in a large open fiel... |
23249745 Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation. In the absence of elongation factor EF-G, ribosomes undergo spontaneous, thermally driven fluctuation between the pre-translocation (classical) and intermediate (hybrid) states of translocation. These fluctuations... |
23249747 Circular RNAs are abundant, conserved, and associated with ALU repeats. Circular RNAs composed of exonic sequence have been described in a small number of genes. Thought to result from splicing errors, circular RNA species possess no known function. To delineate the universe of endogenous circular RNAs, we per... |
23250357 The effect of a bile acid sequestrant on glucose metabolism in subjects with type 2 diabetes. We designed an experiment to examine the effect of bile acid sequestration with Colesevelam on fasting and postprandial glucose metabolism in type 2 diabetes. To do so, we tested the hypothesis that Colesevelam increa... |
23250541 Comparison of tissue metal concentrations in Zucker lean, Zucker obese, and Zucker diabetic fatty rats and the effects of chromium supplementation on tissue metal concentrations. Diabetes results in several metabolic changes, including alterations in the transport, distribution, excretion, and accumulation of ... |
23250811 Curcumin improves TNBS-induced colitis in rats by inhibiting IL-27 expression via the TLR4/NF-κB signaling pathway. Curcumin is a widely used spice with anti-inflammatory and anticancer properties. It has been reported to have beneficial effects in experimental colitis. This study explored whether curcumin imp... |
23252421 Lightweight and strong cellulose materials made from aqueous foams stabilized by nanofibrillated cellulose. A lightweight and strong porous cellulose material has been prepared by drying aqueous foams stabilized with surface-modified nanofibrillated cellulose (NFC). This material differs from other dry, partic... |
23252481 Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: core redesign. The total synthesis of a systematic series of vinblastine analogues that contain deep-seated structural modifications to the core ring system of the lower... |
23252610 Analysis of 4-Hydroxy-1-(3-pyridyl)-1-butanone (HPB)-Releasing DNA Adducts in Human Exfoliated Oral Mucosa Cells by Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry. Quantitation of DNA adducts could provide critical information on the relationship between exposure to tobacco smoke and ca... |
23252823 Pyrenyl-linker-glucono gelators. Correlations of gel properties with gelator structures and characterization of solvent effects. A series of glucono-appended 1-pyrenesulfonyl derivatives containing α,ω-diaminoalkane spacers (Pn, where n, the number of methylene units separating the amino groups, is 2, 3, 4, 6,... |
23252848 Antiproliferative withanolides from Datura wrightii. A new withanolide, named withawrightolide (1), and four known withanolides (2-5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure ... |
23253127 Putative impact of RNA editing on drug discovery. Virtually all organisms use RNA editing as a powerful post-transcriptional mechanism to recode genomic information and to increase functional protein diversity. The enzymatic editing of pre-mRNA by ADARs and CDARs is known to change the functional properties of... |
23253441 The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease. In an attempt to further improve overall profiles of the oxadiazine series of GSMs, in particular the hERG activity, conformational modifications of the core structure resulted in the identification of fuse... |
23253856 Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling. Human WRN and BLM genes are members of the conserved RECQ helicase family. Mutations in these genes are associated with Werner and Bloom syndromes. WRN and BLM proteins are im... |
23254196 Phytoestrogen genistein protects against endothelial barrier dysfunction in vascular endothelial cells through PKA-mediated suppression of RhoA signaling. The soy-derived phytoestrogen genistein has received attention for its potential to improve vascular function, but its mechanism remains unclear. Here, we r... |
23255050 Intrinsically green iron oxide nanoparticles? From synthesis via (eco-)toxicology to scenario modelling. Iron oxide nanoparticles (IONP) are currently being studied as green magnet resonance imaging (MRI) contrast agents. They are also used in huge quantities for environmental remediation and water treatment p... |
23255073 Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer. Metastatic colorectal cancer (mCRC) is frequently characterized by the presence of mutations of the KRAS oncogene, which are generally associated with a poor r... |
23255284 Formation of RNA phosphodiester bond by histidine-containing dipeptides. A new scenario for prebiotic formation of nucleic acid oligomers is presented. Peptide catalysis is applied to achieve condensation of activated RNA monomers into short RNA chains. As catalysts, L-dipeptides containing a histidine residue... |
23255384 Structural and stereochemical studies of hydroxyanthraquinone derivatives from the endophytic fungus Coniothyrium sp. Four known hydroxyanthraquinones (1-4) together with four new derivatives having a tetralone moiety, namely coniothyrinones A-D (5-8), were isolated from the culture of Coniothyrium sp., an end... |
23255471 Tungsten carbide nanoparticles as efficient cocatalysts for photocatalytic overall water splitting. Tungsten carbide exhibits platinum-like behavior, which makes it an interesting potential substitute for noble metals in catalytic applications. Tungsten carbide nanocrystals (≈5 nm) are directly synthesized thr... |
23256442 Dandelion leaf extract protects against liver injury induced by methionine- and choline-deficient diet in mice. We investigated the hepatoprotective effects of the extract of dandelion leaves (EDL) on a murine model of methionine- and choline-deficient (MCD) diet-induced nonalcoholic steatohepatitis (NASH). C5... |
23256445 Trigonelline ameliorates oxidative stress in type 2 diabetic Goto-Kakizaki rats. Previously, we showed that trigonelline (TRG) exerts antidiabetic effects in type 2 diabetic Goto-Kakizaki (GK) rats and also lowers blood and liver thiobarbituric acid reactive substances and urinary 8-hydroxydeoxyguanosine when ... |
23256446 Metabolic effects of honey in type 1 diabetes mellitus: a randomized crossover pilot study. The aim of this study was to evaluate the metabolic effects of 12-week honey consumption on patients suffering from type 1 diabetes mellitus (DM). This was a randomized crossover clinical trial done in the National Inst... |
23256474 Fit-for-purpose bioanalytical cross-validation for LC-MS/MS assays in clinical studies. The paradigm shift of globalized research and conducting clinical studies at different geographic locations worldwide to access broader patient populations has resulted in increased need of correlating bioanalytical results... |
23256503 Ballistic InAs nanowire transistors. Ballistic transport of electrons at room temperature in top-gated InAs nanowire (NW) transistors is experimentally observed and theoretically examined. From length dependent studies, the low-field mean free path is directly extracted as ~150 nm. The mean free path is found ... |
23256510 Morphology-dependent trap formation in bulk heterojunction photodiodes. We show that local structural variation affects the rate of aging in nanostructured polymer solar cells by comparing time-resolved electrostatic force microscopy (trEFM) and conventional device measurements on model polymer blends. Specifi... |
23256609 First-principles prediction of the effects of temperature and solvent selection on the dimerization of benzoic acid. We introduce a procedure of quantum chemical calculations (B3P86/6-31G**) to study carboxylic acid dimerization and its correlation with temperature and properties of the solvent. Benzoic acid i... |
23256621 Universal concept for the implementation of a single cleavable unit at tunable position in functional poly(ethylene glycol)s. Poly(ethylene glycol) (PEG) with acid-sensitive moieties gained attention particularly for various biomedical applications, such as the covalent attachment of PEG (PEGylation) to protei... |
23256640 Enhancing biocompatibility of D-oligopeptide hydrogels by negative charges. Oligopeptide hydrogels are emerging as useful matrices for cell culture with commercial products on the market, but L-oligopeptides are labile to proteases. An obvious solution is to create D-oligopeptide hydrogels, which lack enzymati... |
23256643 Magnetostructural correlation for rational design of Mn(II) hybrid-spin complexes. The magnetic properties of a series of manganese(II) diacetylacetonate and dihexafluoroacetylacetonate hybrid-spin complexes with neutral pyridine-based organic radicals were characterized theoretically by DFT calculations. Thre... |
23256719 Antioxidants and mucolytics in COPD management: when (if ever) and in whom? Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Oxidative stress is an important mechanism in the pathogenesis of this disease. The oxidant/ antioxidant imbalance occurring in smokers... |
23256723 Effect of rehabilitative exercise training on peripheral muscle remodelling in patients with COPD: targeting beyond the lungs. Locomotor muscle dysfunction and weakness are frequently observed in patients with Chronic Obstructive Pulmonary Disease (COPD). In addition to intolerable sensations of dyspnoea which... |
23256724 Clonazepam for the treatment of panic disorder. Clonazepam was initially licensed as an anti-epileptic agent, but its use in a wide variety of psychiatric conditions, including panic disorder (PD) has now been well established. This overview evaluates the current role of clonazepam alone or in combination with... |
23256769 Effects of formation conditions on the physicochemical properties, aggregation, and phase transformation of iron oxide nanoparticles. In this work, hematite transformation from a precursor 6-line ferrihydrite phase was investigated by systematically altering the forced hydrolysis hematite synthesis. Specifical... |
23256816 The evolution of S100B inhibitors for the treatment of malignant melanoma. Malignant melanoma continues to be an extremely fatal cancer due to a lack of viable treatment options for patients. The calcium-binding protein S100B has long been used as a clinical biomarker, aiding in malignant melanoma staging and ... |
23256819 HR-MAS NMR Spectroscopy of Reconstructed Human Epidermis: Potential for the in Situ Investigation of the Chemical Interactions between Skin Allergens and Nucleophilic Amino Acids. High-resolution magic angle spinning (HR-MAS) is a nuclear magnetic resonance (NMR) technique that enables the characterization of ... |
23258537 The RNA polymerase of marine cyanophage Syn5. A single subunit DNA-dependent RNA polymerase was identified and purified to apparent homogeneity from cyanophage Syn5 that infects the marine cyanobacteria Synechococcus. Syn5 is homologous to bacteriophage T7 that infects Escherichia coli. Using the purified enzy... |
23258671 Super-stable ultrafine beta-tungsten nanocrystals with metastable phase and related magnetism. Ultrafine tungsten nanocrystals (average size of 3 nm) with a metastable phase (beta-tungsten with A15 structure, β-W) have been prepared by laser ablation of tungsten in liquid nitrogen. The as-prepared metastable n... |
23258708 The comprehensive epigenome map of piRNA clusters. PIWI-interacting RNA (piRNA) clusters act as anti-transposon/retrovirus centers. Integration of selfish jumping elements into piRNA clusters generates de novo piRNAs, which in turn exert trans-silencing activity against these elements in animal gonads. To date... |
23258742 A three-generational study of In ovo exposure to PBDE-99 in the zebra finch. Based on a literature review of avian data for polybrominated diphenyl ethers (PBDEs), ecologically relevant doses, low (10 ng/egg), medium (100 ng/egg), and high (1,000 ng/egg) of the 2,2',4,4',5-pentabromodiphenyl ether (BDE-99) con... |
23258773 Assessing ongoing sources of dissolved-phase polychlorinated biphenyls in a contaminated stream. Few studies assess the potential of ongoing sources of "fresh" polychlorinated biphenyls (PCBs) to aquatic systems when direct discharge to the environment has been eliminated. In the present study, the authors use... |
23259536 Photonic modulation of electron transfer with switchable phase inversion. Photochromes may be reversibly photoisomerized between two metastable states and their properties can influence, and be influenced by, other chromophores in the same molecule through energy or electron transfer. In the photochemically ac... |
23259666 Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface. Vancomycin represents the preferred ligand for bacteria-targeting nanosystems. However, it is inefficient for emerging vancomycin-resistant species because of its poor affinity to the reprogrammed cell wall ... |
23259742 Short-channel transistors constructed with solution-processed carbon nanotubes. We develop short-channel transistors using solution-processed single-walled carbon nanotubes (SWNTs) to evaluate the feasibility of those SWNTs for high-performance applications. Our results show that even though the intrinsic fiel... |
23259773 Freeze fracture approach to directly visualize wetting transitions on nanopatterned superhydrophobic silicon surfaces: more than a proof of principle. Freeze fracturing is applied to make the wetting behavior of artificially nanopatterned Si surfaces directly visible. For this purpose, almost hexagonally arran... |
23259865 Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1). Tyrosyl-DNA phosphodiesterase I (Tdp1) plays a key role in the repair of damaged DNA resulting from the topoisomerase I (Top1) inhibitor camptothecin and a variety of ... |
23259866 Morphologies of ABC triblock terpolymer melts containing poly(cyclohexadiene): effects of conformational asymmetry. We have synthesized linear ABC triblock terpolymers containing poly(1,3-cyclohexadiene), PCHD, as an end block and characterized their morphologies in the melt. Specifically, we have studied terp... |
23259985 Bioreducible polymers as a determining factor for polyplex decomplexation rate and transfection. Polyplex formation (complexation) and gene release from the polyplexes (decomplexation) are major events in polymeric gene delivery; however, the effect of the decomplexation rate on transfection has been rarely in... |
23260032 Exploring the Toxicity of a Bismuth-Asparagine Coordination Polymer on the Early Development of Zebrafish Embryos. Nanoparticles are widely used in nanomedicine, raising concerns about their toxicity. In this study, the toxicity of bismuth-asparagine coordination polymer spheres (BACP-2) was assessed in zebraf... |
23260347 Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5. Diphenylphosphinic amides and diphenylphosphine oxides have been synthesized and tested as inhibitors of the Kv1.5 potassium ion channel as a possible treatment for atrial fibrillation. In vitro structure... |
23260352 Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold. A novel series of anti-malarials, based on a hydroxy-ethyl-amine scaffold, initially identified as peptidomimetic protease inhibitors is described. Combination of the hydroxy-ethyl-amine anti-malarial phramacophore with the known Mann... |
23261524 Live-cell imaging of p53 interactions using a novel Venus-based bimolecular fluorescence complementation system. p53 plays an important role in regulating a wide variety of cellular processes, such as cell cycle arrest and/or apoptosis. Dysfunction of p53 is frequently associated with several pathologies, such... |
23261527 Emerging targets in lipid-based therapy. The use of prostaglandins and NSAIDS in the clinic has proven that lipid mediators and their associated pathways make attractive therapeutic targets. When contemplating therapies involving lipid pathways, several basic agents come to mind. There are the enzymes and acce... |
23261528 Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the intestine which involves overproduction of pro-infla... |
23261588 Short and long-term exposure of CNS cell lines to BPA-f a radiosensitizer for Boron Neutron Capture Therapy: safety dose evaluation by a battery of cytotoxicity tests. Despite the current clinical use of boronophenylalanine-fructose (BPA-f), as radiosensitizer, in BNCT application for brain tumors, still remai... |
23261590 Neoechinulin A suppresses amyloid-β oligomer-induced microglia activation and thereby protects PC-12 cells from inflammation-mediated toxicity. A pathological hallmark of Alzheimer's disease (AD), aggregation and deposition of amyloid-β peptides, has been recognized as a potent activator of microglia-mediated ... |
23261644 A comparative performance test of standard, medium- and high-throughput comet assays. A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the restriction on the number of samples that can be processed in one experiment, imposed by the size of the electrophoresis platform. ... |
23261645 The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity. Jaspamide (jasplakinolide; NSC-613009) is a cyclodepsipeptide that has antitumor activity. A narrow margin of safety was observed between doses required for efficacy in mouse tumor models and doses that caused severe acu... |
23261667 Long-term incubation of adult Nereis virens (Annelida: Polychaeta) in copper-spiked sediment: the effects on adult mortality, gametogenesis, spawning and embryo development. Late gametogenic Nereis virens were incubated for up to 2.5 months in environmentally relevant concentrations of copper-spiked sediment. ... |
23261676 (-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats. Cardiac mitochondrial damage plays an important role in the pathology of myocardial infarction. The protective effects... |
23261705 Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway. The present study examined the effect of insulin-mediated activation of the mammalian target of rapamycin complex 1 (MTORC1) signaling network on the proliferation of prim... |
23261715 Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents. Rabbit aldo-keto reductase (AKR) 1B19 is an ortholog of human aldose reductase-like protein (ARLP), AKR1B10, showing 86% amino acid sequence identity. AKR1B19 exhibits the... |
23261820 The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat. Triclosan (TCS), an antibacterial, has been shown to be an endocrine disruptor in the rat. We reported previously that TCS potentiated the estrogenic effect of ethinyl estradiol (EE) on uterine grow... |
23262162 Antioxidant cosmeto-textiles: Skin assessment. Resveratrol, a natural product, has been reported to have antioxidant activities such as the scavenging of free radicals. This compound could be used in the dermocosmetic field to protect the skin from oxidative stress. In this work, the percutaneous profile of re... |
23262203 Plasmonic photothermal therapy increases the tumor mass penetration of HPMA copolymers. Effective drug delivery to tumors requires both transport through the vasculature and tumor interstitium. Previously, it was shown that gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) is capable of increas... |
23262279 High-throughput identification and characterization of novel, species-selective GPR35 agonists. Drugs targeting the orphan receptor GPR35 have potential therapeutic application in a number of disease areas, including inflammation, metabolic disorders, nociception, and cardiovascular disease. Currently availabl... |
23262390 Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates. Aggregation of α-synuclein (α-syn) in the brain is a defining pathological feature of neurodegenerative disorders classified as synucleinopathies. They include Parkinson's disease (PD), dementia with Lewy bodies (DL... |
23263987 Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1. The prototypic second messenger cyclic AMP (cAMP) is essential for controlling cellular metabolism, including glucose and lipid homeostasis. In mammals, ... |
23264021 Molecular diversity of class 2 integrons in antibiotic-resistant gram-negative bacteria found in wastewater environments in China. The molecular architecture of class 2 integrons among gram-negative bacteria from wastewater environments was investigated in Jinan, China. Out of the 391 antibiotic-resistant bact... |
23264030 Effects of fluoxetine on the swimming and behavioural responses of the Arabian killifish. The selective serotonin reuptake inhibitor fluoxetine has frequently been detected in surface waters around the world. Fluoxetine modulates levels of serotonin, a neurotransmitter that regulates several important physiolo... |
23264615 Cortisol and interferon tau regulation of endometrial function and conceptus development in female sheep. During early pregnancy in sheep, the elongating conceptus secretes interferon-τ (IFNT) and the conceptus as well as endometrial epithelia produce prostaglandins (PG) via PG synthase 2 (PTGS2) and cortisol ... |
23265282 Streamlined expressed protein ligation using split inteins. Chemically modified proteins are invaluable tools for studying the molecular details of biological processes, and they also hold great potential as new therapeutic agents. Several methods have been developed for the site-specific modification of prote... |
23265296 Block copolymer modified surfaces for conjugation of biomacromolecules with control of quantity and activity. Polymer brush layers based on block copolymers of poly(oligo(ethylene glycol) methacrylate) (POEGMA) and poly(glycidyl methacrylate) (PGMA) were formed on silicon wafers by activators generated by elec... |
23265429 Electrodeposition of crystalline GaAs on liquid gallium electrodes in aqueous electrolytes. Crystalline GaAs (c-GaAs) has been prepared directly through electroreduction of As(2)O(3) dissolved in an alkaline aqueous solution at a liquid gallium (Ga(l)) electrode at modest temperatures (T ≥ 80 °C). Ga(l) pool e... |
23265452 The determination of phenolic profiles of Serbian unifloral honeys using ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry. Polyphenolic profiles of 44 unifloral Serbian honeys were analyzed using ultra-high-performance liquid chromatography (UHPLC) coupled with hybrid mas... |
23265456 Fast HPLC-DAD quantification of nine polyphenols in honey by using second-order calibration method based on trilinear decomposition algorithm. This paper describes the use of second-order calibration for development of HPLC-DAD method to quantify nine polyphenols in five kinds of honey samples. The sample trea... |
23265458 Defatted Jatropha curcas flour and protein isolate as materials for protein hydrolysates with biological activity. Jatropha curcas L. protein hydrolysates were produced by treatment of a non-toxic genotype with Alcalase as well as the digestive enzymes pepsin and pancreatin. The J. curcas protein hydrolysate p... |
23265462 Transepithelial transport of 6-O-caffeoylsophorose across Caco-2 cell monolayers. The aim of this study was to clarify the transport behaviour and mechanism of caffeic acid analogue bearing a sugar-moiety, 6-O-caffeoylsophorose (CS), in Caco-2 cells. The absorption of CS was investigated by its transport acros... |
23265467 Sugarcane bagasse treated with hydrous ferric oxide as a potential adsorbent for the removal of As(V) from aqueous solutions. The mechanism of As(V) removal from aqueous solutions by means of hydrated ferric oxide (HFO)-treated sugarcane bagasse (SCB-HFO) (Saccharum officinarum L.) was investigated. Effects of... |
23265469 Enzymatic synthesis of fructooligosaccharides by inulinases from Aspergillus niger and Kluyveromyces marxianus NRRL Y-7571 in aqueous-organic medium. This work is focused on the synthesis of the fructooligosaccharides (FOS) from sucrose and inulin, using free, immobilized and pre-treated immobilized inulinase ... |
23265483 Review: on published data and methods for selenium in mushrooms. Selected data published on selenium in several species of mushrooms are outlined and discussed in light of performance of analytical methods employed. Data was shown to be either dubious or concentrations too high to be credible and valid in some... |
23265488 Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-β activation to enhance protein degradation and attenuate nuclear translocation of β-catenin. The aim of our study was to investigate the mechanisms by which rhubarb regulates β-catenin as well as metastasis of hepatocellular carcinomas. Our r... |
23265491 Evaluation of biological activities of a groundnut (Apios americana Medik) extract containing a novel isoflavone. Groundnut (Apios americana Medik) contains a novel isoflavone, genistein-7-O-gentiobioside. In the present study, we examined the biological activities of an alcohol extract of groundnut containing... |
23265492 Three sulphated polysaccharides isolated from the mucilage of mud snail, Bullacta exarata philippi: characterization and antitumour activity. Three sulphated polysaccharides, coded as BEMPA, BEMPB(1), BEMPB(2), were extracted from the mucilage of mud snail of Bullacta exarata and purified by DEAE-cellulose ion... |
23265498 Development and validation of a real-time PCR method for the simultaneous detection of black mustard (Brassica nigra) and brown mustard (Brassica juncea) in food. The paper presents a real-time PCR method allowing the simultaneous detection of traces of black mustard (Brassica nigra) and brown mustard (Brassic... |
23265501 Physical attributes and chemical composition of organic strawberry fruit (Fragaria x ananassa Duch, Cv. Albion) at six stages of ripening. Organic strawberry fruits (Cv. 'Albion') were harvested at six different ripening stages and evaluated for physical and chemical parameters. Biometrical characteristics and... |
23265502 Ascorbic acid, nitrate, and nitrite concentration relationship to the 24hour light/dark cycle for spinach grown in different conditions. Nitrate, nitrite and ascorbic acid (vitamin C) concentrations were determined for spinach (Spinacia oleracea L.) over a 24 h period to determine if light intensity (including... |
23265504 Physico-chemical and antioxidant properties of four mango (Mangifera indica L.) cultivars in China. Four principal mango cultivars (Tainong No.1, Irwin, JinHwang and Keitt) grown in southern China were selected, and their physico-chemical and antioxidant properties were characterized and compared. Of all the f... |
23265506 EC50 estimation of antioxidant activity in DPPH· assay using several statistical programs. DPPH(·) assay is a reliable method to determine the antioxidant capacity of biological substrates. The DPPH(·) radical scavenging activity is generally quantified in terms of inhibition percentage of the pre-formed free ... |
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