license: mit
DMS-Fold2 Benchmark Dataset
This repository contains the benchmark datasets used to evaluate DMS-Fold2. The files are organized into two benchmark sets:
- CASP/CAMEO targets (
casp_cameo_targets/) - Mega-scale targets (
megascale_targets/)
Each target includes the sequence and experimental data required to reproduce the benchmark inputs.
Directory Structure
paper_benchmarks/
├── casp_cameo_targets/
│ ├── alignments.tar.gz
│ ├── fastas/
│ ├── pdbs/
│ ├── dm_csvs/
│ └── sm_csvs/
└── megascale_targets/
├── alignments.tar.gz
├── fastas/
├── pdbs/
├── dm_csvs/
└── sm_csvs/
Contents
alignments.tar.gz
Compressed archive containing one directory per protein target with precomputed multiple sequence alignments (MSAs).
fastas/
FASTA sequences for each benchmark protein.
pdbs/
PDB files for each benchmark protein.
dm_csvs/
Double-mutant deep mutational scanning (DMS) datasets used as input to DMS-Fold2.
sm_csvs/
Single-mutant deep mutational scanning (DMS) datasets used as input to DMS-Fold2.
Benchmark Sets
megascale_targets
Benchmark proteins selected from the Mega-scale DMS collection.
casp_cameo_targets
Benchmark proteins from CASP14, CASP15, and CAMEO.
Citation
If you use this dataset, please cite the accompanying DMS-Fold2 publication.
