LiteFold/DisProt · Datasets at Hugging Face

DP02302

Q15843

UPI00000009A5

NEDD8

Homo sapiens

9,606

81

0.160494

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-08-31T18:32:18.000Z

jpujols

UniRef100_Q15843

UniRef90_Q15843

UniRef50_Q15843

MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLRQ

3

[ "DP02302r001", "DP02302r002", "DP02302r003" ]

[ 69, 69, 69 ]

[ 81, 81, 81 ]

[ 13, 13, 13 ]

[ "disorder", "disorder to order", "protein binding" ]

[ "IDPO:0000002", "IDPO:0000011", "GO:0005515" ]

[ "Structural state", "Structural transition", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "14690597", "14690597", "14690597" ]

[ "pmid", "pmid", "pmid" ]

[ "András Hatos", "András Hatos", "András Hatos" ]

[ "PDB:1R4M" ]

[ "gene3D", "pfam" ]

[ "3.10.20.90", "PF00240" ]

[ "Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1", "Ubiquitin family" ]

2

[ "NEDD8" ]

[ 69 ]

[ 81 ]

[ "T" ]

1

DP02303

Q0JRZ9

UPI000019971A

F-BAR domain only protein 2

Homo sapiens

9,606

810

0.019753

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-08-31T18:40:14.000Z

baykac

UniRef100_Q0JRZ9

UniRef90_Q3UQN2

UniRef50_Q3UQN2

MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDE...

1

[ "DP02303r001" ]

[ 259 ]

[ 274 ]

[ 16 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "17540576" ]

[ "pmid" ]

[ "Burcu Aykac-Fas" ]

[ "PDB:2V0O" ]

[ "gene3D", "pfam", "pfam" ]

[ "1.20.1270.60", "PF10291", "PF22699" ]

[ "Arfaptin homology (AH) domain/BAR domain", "Muniscin C-terminal mu homology domain", "GEM-interacting protein-like, FCH domain" ]

3

[ "FCHO2" ]

[ 259 ]

[ 274 ]

[ "D" ]

7

DP02309

Q96RF0

UPI0000135B4F

Sorting nexin-18

Homo sapiens

9,606

628

0.264331

[ "Autophagy-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-08-31T20:07:08.000Z

vsagris

UniRef100_Q96RF0

UniRef90_Q96RF0

UniRef50_Q96RF0

MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQPPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLY...

7

[ "DP02309r003", "DP02309r004", "DP02309r005", "DP02309r006", "DP02309r007", "DP02309r008", "DP02309r009" ]

[ 154, 154, 154, 154, 154, 154, 59 ]

[ 158, 158, 158, 158, 158, 158, 224 ]

[ 5, 5, 5, 5, 5, 5, 166 ]

[ "protein binding", "protein binding", "selective autophagy", "selective autophagy", "protein binding", "protein binding", "disorder" ]

[ "GO:0005515", "GO:0005515", "GO:0061912", "GO:0061912", "GO:0005515", "GO:0005515", "IDPO:0000002" ]

[ "Molecular function", "Molecular function", "Biological process", "Biological process", "Molecular function", "Molecular function", "Structural state" ]

[ "ECO:0001245", "ECO:0000315", "ECO:0001245", "ECO:0000315", "ECO:0007689", "ECO:0000279", "ECO:0000302" ]

[ "23878278", "23878278", "23878278", "23878278", "23878278", "23878278", "29437695" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Vasileios Sagris", "Vasileios Sagris", "Vasileios Sagris", "Vasileios Sagris", "Vasileios Sagris", "Vasileios Sagris", "Victoria Nugnes" ]

[]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "3.30.1520.10", "1.20.1270.60", "2.30.30.40", "PF00787", "PF10456", "PF14604" ]

[ "Phox-like domain", "Arfaptin homology (AH) domain/BAR domain", "SH3 Domains", "PX domain", "WASP-binding domain of Sorting nexin protein", "Variant SH3 domain" ]

6

[ "SH3PXD3B", "SNX18" ]

[ 59 ]

[ 224 ]

[ "D" ]

1

DP02311

Q7DD77

UPI00000C4E86

PilP protein

Neisseria meningitidis serogroup B (strain MC58)

122,586

181

0.458564

[]

[ "Bacteria", "Proteobacteria", "Betaproteobacteria", "Neisseriales", "Neisseriaceae", "Neisseria" ]

2018_11

2018-08-31T20:33:12.000Z

thorvath

UniRef100_A0A0E1I940

UniRef90_A0A7U8ZGF4

UniRef50_E4ZF16

MKHYALLISFLALSACSQGSEDLNEWMAQTRREAKAEIIPFQAPTLPVAPVYSPPQLTGPNAFDFRRMETDKKGENAPDTKRIKETLEKFSLENMRYVGILKSGQKVSGFIEAEGYVYTVGVGNYLGQNYGRIESITDDSIVLNELIEDSTGNWVSRKAELLLNSSDKNTEQAAAPAAEQN

3

[ "DP02311r001", "DP02311r002", "DP02311r003" ]

[ 69, 20, 164 ]

[ 84, 69, 181 ]

[ 16, 50, 18 ]

[ "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006165", "ECO:0007691", "ECO:0006165" ]

[ "17007878", "17007878", "17007878" ]

[ "pmid", "pmid", "pmid" ]

[ "Edoardo Salladini", "Edoardo Salladini", "Edoardo Salladini" ]

[ "PDB:2IVW" ]

[ "gene3D", "pfam" ]

[ "2.30.30.830", "PF04351" ]

[ "2.30.30.830", "Pilus assembly protein, PilP" ]

2

[ "NMB1811", "pilP" ]

[ 20, 164 ]

[ 84, 181 ]

[ "D", "D" ]

2

DP02312

Q8T9B6

UPI000005E9F2

LDLR chaperone boca

Drosophila melanogaster

7,227

180

0.405556

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]

2018_11

2018-08-31T20:33:24.000Z

vpromp

UniRef100_Q8T9B6

UniRef90_Q8T9B6

UniRef50_Q8T9B6

MQTRLVLLLLALTPLVLAKKFKEEEKPAWAKKDIRDYSEADLERLLDQWEEDEEPLEDDELPEHLRPQPKLDLSNLDSKSPEDLLKVSKKGRTLMTFVSVTGNPTREESDTITKLWQTSLWNNHIQAERYMVDDNRAIFLFKDGTQAWDAKDFLIEQERCKGVTIENKEYPGVNAKKDEL

2

[ "DP02312r001", "DP02312r002" ]

[ 19, 31 ]

[ 91, 91 ]

[ 73, 61 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0007691", "ECO:0006165" ]

[ "21397184", "21397184" ]

[ "pmid", "pmid" ]

[ "Victoria Nugnes", "Victoria Nugnes" ]

[]

[ "gene3D", "gene3D", "pfam" ]

[ "3.30.70.260", "3.30.70.260", "PF10185" ]

[ "3.30.70.260", "3.30.70.260", "Chaperone for wingless signalling and trafficking of LDL receptor" ]

3

[ "CG30498", "boca" ]

[ 19 ]

[ 91 ]

[ "D" ]

8

DP02313

Q8IG33

UPI00000851E4

Boca/MESD chaperone for YWTD beta-propeller-EGF

Caenorhabditis elegans

6,239

186

0.38172

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Nematoda", "Chromadorea", "Rhabditida", "Rhabditina", "Rhabditomorpha", "Rhabditoidea", "Rhabditidae", "Peloderinae", "Caenorhabditis" ]

2018_11

2018-08-31T20:41:48.000Z

vpromp

UniRef100_Q8IG33

UniRef90_Q8IG33

UniRef50_Q8IG33

MKWRTVFIFLLAAHIGLANVKQKKKDLSSYTDAELEKLYEEWEENDEDELEEDEKPEHKRKPPQLDLESMKAKAKDPEDLLMMSKKGQTLMLFVGVVDPSQPDRSDIRPFTEKWTQIWQSQLYNNHVDLQVFVIDDNRAIFMFKNGEQAFEAKKFLLKQEFVSEVTIEGQSFDGPAKKFKTGKKEL

1

[ "DP02313r001" ]

[ 18 ]

[ 88 ]

[ 71 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0007691" ]

[ "21397184" ]

[ "pmid" ]

[ "Victoria Nugnes" ]

[]

[ "gene3D", "pfam" ]

[ "3.30.70.260", "PF10185" ]

[ "3.30.70.260", "Chaperone for wingless signalling and trafficking of LDL receptor" ]

2

[ "CELE_F09E5.17", "F09E5.17", "bmy-1" ]

[ 18 ]

[ 88 ]

[ "D" ]

6

DP02314

Q9ERE7

UPI000000410C

LRP chaperone MESD

Mus musculus

10,090

224

0.330357

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2018_11

2018-08-31T20:46:59.000Z

vpromp

UniRef100_Q9ERE7

UniRef90_Q9ERE7

UniRef50_Q9ERE7

MAASRWLRAVLLFLCASDLLLLPPPNAYAADTPGEATPPPRKKKDIRDYNDADMARLLEQWEKDDDIEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTVSGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVSQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKAKKKEGDPKPRASKEDNRAGSRREDL

2

[ "DP02314r001", "DP02314r002" ]

[ 30, 29 ]

[ 102, 92 ]

[ 73, 64 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0007691", "ECO:0007691" ]

[ "21397184", "17488095" ]

[ "pmid", "pmid" ]

[ "Victoria Nugnes", "Vasilis J Promponas" ]

[]

[ "gene3D", "gene3D", "pfam" ]

[ "3.30.70.260", "3.30.70.260", "PF10185" ]

[ "3.30.70.260", "3.30.70.260", "Chaperone for wingless signalling and trafficking of LDL receptor" ]

3

[ "Mesd", "Mesdc2" ]

[ 29 ]

[ 102 ]

[ "D" ]

5

DP02316

O43663

UPI00001A5ED8

Protein regulator of cytokinesis 1

Homo sapiens

9,606

620

0.274194

[ "Cancer-related proteins", "Condensates-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-08-31T23:03:05.000Z

vpromp

UniRef100_O43663

UniRef90_O43663

UniRef50_O43663

MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAP...

3

[ "DP02316r001", "DP02316r002", "DP02316r003" ]

[ 467, 467, 451 ]

[ 620, 620, 486 ]

[ 154, 154, 36 ]

[ "disorder", "protein binding", "disorder" ]

[ "IDPO:0000002", "GO:0005515", "IDPO:0000002" ]

[ "Structural state", "Molecular function", "Structural state" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "20691902", "20691902", "23870126" ]

[ "pmid", "pmid", "pmid" ]

[ "Vasilis J Promponas", "Vasilis J Promponas", "Vasilis J Promponas" ]

[ "PDB:3NRX", "PDB:3NRY", "PDB:4L3I" ]

[ "gene3D", "pfam" ]

[ "1.20.58.1520", "PF03999" ]

[ "1.20.58.1520", "Microtubule associated protein (MAP65/ASE1 family)" ]

2

[ "PRC1" ]

[ 451 ]

[ 620 ]

[ "D" ]

1

DP02317

Q03689

UPI0000168953

Heterokaryon incompatibility protein s

Podospora anserina

5,145

289

0.214533

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Pezizomycotina", "Sordariomycetes", "Sordariomycetidae", "Sordariales", "Chaetomiaceae", "Podospora" ]

2018_11

2018-09-01T00:24:39.000Z

vpromp

UniRef100_Q03689

UniRef90_Q03689

UniRef50_Q03689

MSEPFGIVAGALNVAGLFNNCVDCFEYVQLGRPFGRDYERCQLRLDIAKARLSRWGEAVKINDDPRFHSDAPTDKSVQLAKSIVEEILLLFESAQKTSKRYELVADQQDLVVFEDKDMKPIGRALHRRLNDLVSRRQKQTSLAKKTAWALYDGKSLEKIVDQVARFVDELEKAFPIEAVCHKLAEIEIEEVEDEASLTILKDAAGGIDAAMSDAAAQKIDAIVGRNSAKDIRTEERARVQLGNVVTAAALHGGIRISDQTTNSVETVVGKGESRVLIGNEYGGKGFWDN

1

[ "DP02317r001" ]

[ 228 ]

[ 289 ]

[ 62 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006165" ]

[ "20620958" ]

[ "pmid" ]

[ "Vasilis J Promponas" ]

[]

[ "gene3D", "pfam", "pfam" ]

[ "1.20.120.1020", "PF11558", "PF14479" ]

[ "Prion-inhibition and propagation, HeLo domain", "Het-s 218-289", "Prion-inhibition and propagation" ]

3

[ "het-s", "small s" ]

[ 228 ]

[ 289 ]

[ "D" ]

8

DP02318

O14672

UPI00001254C8

Disintegrin and metalloproteinase domain-containing protein 10

Homo sapiens

9,606

748

0.069519

[ "Extracellular matrix proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-09-01T00:25:57.000Z

jpujols

UniRef100_O14672

UniRef90_O14672

UniRef50_O14672

MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTD...

5

[ "DP02318r001", "DP02318r004", "DP02318r005", "DP02318r006", "DP02318r007" ]

[ 697, 697, 697, 697, 697 ]

[ 748, 748, 748, 748, 748 ]

[ 52, 52, 52, 52, 52 ]

[ "disorder", "order", "disorder to order", "protein homodimerization activity", "protein homodimerization activity" ]

[ "IDPO:0000002", "IDPO:0000006", "IDPO:0000011", "GO:0042803", "GO:0042803" ]

[ "Structural state", "Structural state", "Structural transition", "Molecular function", "Molecular function" ]

[ "ECO:0006204", "ECO:0006204", "ECO:0006204", "ECO:0001183", "ECO:0005636" ]

[ "25349418", "25349418", "25349418", "25349418", "25349418" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]

[]

[ "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "3.40.390.10", "4.10.70.10", "PF00200", "PF13574", "PF21299" ]

[ "Collagenase (Catalytic Domain)", "Disintegrin domain", "Disintegrin", "Metallo-peptidase family M12B Reprolysin-like", "ADAM10, cysteine-rich domain" ]

5

[ "ADAM10", "KUZ", "MADM" ]

[ 697 ]

[ 748 ]

[ "T" ]

6

DP02320

P0C8E0

UPI00017B8D56

Conantokin-Pr1

Conus parius

505,247

19

1

[]

[ "Eukaryota", "Metazoa", "Spiralia", "Lophotrochozoa", "Mollusca", "Gastropoda", "Caenogastropoda", "Neogastropoda", "Conoidea", "Conidae", "Conus", "Phasmoconus" ]

2018_11

2018-09-01T01:05:40.000Z

vpromp

UniRef100_P0C8E0

UniRef90_P0C8E0

UniRef50_P0C8E0

GEDEYAEGIREYQLIHGKI

1

[ "DP02320r001" ]

[ 1 ]

[ 19 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006204" ]

[ "17962189" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[]

0

[]

[ 1 ]

[ 19 ]

[ "D" ]

5

DP02321

P0C8E1

UPI00017B8D57

Conantokin-Pr2

Conus parius

505,247

19

1

[]

[ "Eukaryota", "Metazoa", "Spiralia", "Lophotrochozoa", "Mollusca", "Gastropoda", "Caenogastropoda", "Neogastropoda", "Conoidea", "Conidae", "Conus", "Phasmoconus" ]

2018_11

2018-09-01T01:13:52.000Z

vpromp

UniRef100_P0C8E1

UniRef90_P0C8E1

UniRef50_P0C8E1

DEPEYAEAIREYQLKYGKI

1

[ "DP02321r001" ]

[ 1 ]

[ 19 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006204" ]

[ "17962189" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[]

0

[]

[ 1 ]

[ 19 ]

[ "D" ]

8

DP02322

A0LU48

UPI00006BF0FF

Depupylase

Acidothermus cellulolyticus (strain ATCC 43068 / 11B)

351,607

503

0.089463

[]

[ "Bacteria", "Actinobacteria", "Acidothermales", "Acidothermaceae", "Acidothermus" ]

2018_11

2018-09-01T01:46:18.000Z

vpromp

UniRef100_A0LU48

UniRef90_A0LU48

UniRef50_A0LU48

MHRVMGIETEYGISVPHQPNANAMAASSQVVNAYAPIGAPAQRQARWDFEEENPLRDARGFEVAREAADPSQLTDEDLGLANVILTNGARLYVDHAHPEYSTPEVTNPRDAVLWDKAGERIMAEAARRAADLPMGWTIQLYKNNTDNKGASYGCHENYLMNRSTPFADIVRHLIPFFVTRQVFCGAGRVGIGADGRGEGFQLSQRADFFEVEVGLETTLKRPIINTRDEPHADPEKYRRLHVIIGDANMSEIATYLKLGTTALVLAMIEDGFLSQDFSVESPVGALRAVSHDPTLRYQLRLHDGRRLTAVQLQMEYLEQA...

1

[ "DP02322r001" ]

[ 36 ]

[ 80 ]

[ 45 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "22910360" ]

[ "pmid" ]

[ "Victoria Nugnes" ]

[ "PDB:4B0R" ]

[ "pfam" ]

[ "PF03136" ]

[ "Pup-ligase protein" ]

1

[ "Acel_1186", "dop" ]

[ 36 ]

[ 80 ]

[ "D" ]

8

DP02323

Q5L0X5

UPI0000496D3B

Cell division protein DivIB

Geobacillus kaustophilus (strain HTA426)

235,909

261

0.118774

[]

[ "Bacteria", "Firmicutes", "Bacilli", "Bacillales", "Bacillaceae", "Geobacillus", "Geobacillus thermoleovorans group" ]

2018_11

2018-09-01T03:00:05.000Z

vpromp

UniRef100_Q5L0X5

UniRef90_Q5L0X5

UniRef50_Q5L0X5

MEKGKVVVLEDRVPKLKERRRQKANRRLIAYLSFFFLFILCVLYFQSPLGAVGHVEVSGNRHLTAERIISLSGITKRTSFWKVNEQNVEKKLTRHPEIKEATVEKQLPNTIAIHVREWRRIAYVYDRQTFFPLLENGRLLKQEGTKTAPSDAPVLVGWKDGDAIAEMTGQLAELPAAVLGAMSEIHYKPTREYEDRVIVYMNDGYEVSATIRQFADKLSHYPAIAAALDRNVKGVIHLEVGSYFVPYSPPKKEDGDETTSP

1

[ "DP02323r002" ]

[ 231 ]

[ 261 ]

[ 31 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0007691" ]

[ "16618922" ]

[ "pmid" ]

[ "Victoria Nugnes" ]

[]

[ "gene3D", "gene3D", "pfam", "pfam" ]

[ "3.10.20.310", "3.40.50.10960", "PF03799", "PF08478" ]

[ "membrane protein fhac", "3.40.50.10960", "Cell division protein FtsQ/DivIB, C-terminal", "POTRA domain, FtsQ-type" ]

4

[ "GK1120", "divIB" ]

[ 231 ]

[ 261 ]

[ "D" ]

2

DP02324

P53865

UPI000013BBCA

Chaotic nuclear migration protein 67

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

581

0.017212

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2018_11

2018-09-01T12:24:14.000Z

jpujols

UniRef100_P53865

UniRef90_P53865

UniRef50_P53865

MTDFDLMNFPFHERLDSPVSENGEIKDGEPIPQNWLNENHVGKSILPLFVNPEDVINCNFSNARDSYEENKSPSMDQMNYARNTSYQESPGLQERPKNEKDKSPIGTDVHKKDVPNFIHSTPRENSSKHFTRANEQASAQPTDEHTSPDISIEDCNGAKIFLQNSLSKEDFRMLENVILGYQKKVIELGRDNLRQEERANSLQKELEAATKSNDKTLDNKKKIEEQTVLIENLTKDLSLNKEMLEKANDTIQTKHTALLSLTDSLRKAELFEIPIGILFFDLYDSEENSSKLDHILQEKYPNIKGFLCASQQEELSRISQ...

2

[ "DP02324r001", "DP02324r002" ]

[ 572, 572 ]

[ 581, 581 ]

[ 10, 10 ]

[ "disorder", "flexible C-terminal tail" ]

[ "IDPO:0000002", "IDPO:0000031" ]

[ "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "21454609", "21454609" ]

[ "pmid", "pmid" ]

[ "András Hatos", "András Hatos" ]

[]

[ "gene3D", "pfam" ]

[ "1.20.5.400", "PF11778" ]

[ "1.20.5.400", "Septation initiation" ]

2

[ "CNM67", "N1264", "YNL225C" ]

[ 572 ]

[ 581 ]

[ "D" ]

9

DP02325

O60200

UPI000013B6D1

Mitochondrial distribution and morphology protein 35

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

86

0.174419

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2018_11

2018-09-01T15:17:41.000Z

jpujols

UniRef100_Q05776

UniRef90_Q05776

UniRef50_Q05776

MGNIMSASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSKQWYAYTTCVNAALVKQGIKPALDEAREEAPFENGGKLKEVDK

1

[ "DP02325r001" ]

[ 67 ]

[ 81 ]

[ 15 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006198" ]

[ "26235513" ]

[ "pmid" ]

[ "Jordi Pujols Pujol" ]

[ "PDB:4YTV" ]

[ "pfam" ]

[ "PF05254" ]

[ "Uncharacterised protein family (UPF0203)" ]

1

[ "MDM35", "YKL053C-A" ]

[ 67 ]

[ 81 ]

[ "D" ]

8

DP02326

Q05776

UPI000006984C

Protein UPS1, mitochondrial

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

175

0.057143

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2018_11

2018-09-01T15:24:30.000Z

jpujols

UniRef100_Q05776

UniRef90_Q05776

UniRef50_Q05776

MVLLHKSTHIFPTDFASVSRAFFNRYPNPYSPHVLSIDTISRNVDQEGNLRTTRLLKKSGKLPTWVKPFLRGITETWIIEVSVVNPANSTMKTYTRNLDHTGIMKVEEYTTYQFDSATSSTIADSRVKFSSGFNMGIKSKVEDWSRTKFDENVKKSRMGMAFVIQKLEEARNPQF

3

[ "DP02326r001", "DP02326r002", "DP02326r003" ]

[ 62, 62, 62 ]

[ 71, 71, 71 ]

[ 10, 10, 10 ]

[ "disorder", "molecular function regulator", "lipid binding" ]

[ "IDPO:0000002", "GO:0098772", "GO:0008289" ]

[ "Structural state", "Molecular function", "Molecular function" ]

[ "ECO:0006165", "ECO:0006165", "ECO:0006165" ]

[ "26235513", "26235513", "26235513" ]

[ "pmid", "pmid", "pmid" ]

[ "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol" ]

[ "PDB:4YTW" ]

[ "pfam" ]

[ "PF04707" ]

[ "PRELI-like family" ]

1

[ "UPS1", "YLR193C" ]

[ 62 ]

[ 71 ]

[ "D" ]

5

DP02327

Q00169

UPI000000DAD0

Phosphatidylinositol transfer protein alpha isoform

Homo sapiens

9,606

270

0.451852

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-09-01T15:49:03.000Z

jpujols

UniRef100_Q00169

UniRef90_Q00169

UniRef50_Q00169

MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD

9

[ "DP02327r001", "DP02327r002", "DP02327r003", "DP02327r004", "DP02327r005", "DP02327r006", "DP02327r007", "DP02327r008", "DP02327r009" ]

[ 1, 119, 119, 119, 119, 119, 119, 233, 233 ]

[ 12, 190, 190, 190, 190, 190, 190, 270, 270 ]

[ 12, 72, 72, 72, 72, 72, 72, 38, 38 ]

[ "disorder", "disorder", "molecular recognition display site", "disorder", "protein binding", "lipid binding", "molecular function regulator", "disorder", "order to pre-molten globule" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000037", "IDPO:0000002", "GO:0005515", "GO:0008289", "GO:0098772", "IDPO:0000002", "IDPO:0000016" ]

[ "Structural state", "Structural state", "Disorder function", "Structural state", "Molecular function", "Molecular function", "Molecular function", "Structural state", "Structural transition" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "11104777", "11104777", "11104777", "14962392", "14962392", "14962392", "14962392", "11104777", "11104777" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol", "Jordi Pujols Pujol" ]

[ "PDB:1uw5" ]

[ "gene3D", "pfam" ]

[ "3.30.530.20", "PF02121" ]

[ "3.30.530.20", "Phosphatidylinositol transfer protein" ]

2

[ "PITPN", "PITPNA" ]

[ 1, 119, 233 ]

[ 12, 190, 270 ]

[ "D", "D", "T" ]

9

DP02328

P53779

UPI000002AE11

Mitogen-activated protein kinase 10

Homo sapiens

9,606

464

0.056034

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-09-03T08:12:46.000Z

baykac

UniRef100_P53779

UniRef90_P53779

UniRef50_P53779

MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPA...

1

[ "DP02328r001" ]

[ 206 ]

[ 231 ]

[ 26 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "9739089" ]

[ "pmid" ]

[ "Burcu Aykac-Fas" ]

[ "PDB:1JNK" ]

[ "gene3D", "gene3D", "pfam" ]

[ "3.30.200.20", "1.10.510.10", "PF00069" ]

[ "Phosphorylase Kinase; domain 1", "Transferase(Phosphotransferase) domain 1", "Protein kinase domain" ]

3

[ "JNK3", "JNK3A", "MAPK10", "PRKM10", "SAPK1B" ]

[ 206 ]

[ 231 ]

[ "D" ]

9

DP02330

C4PB33

UPI0001A45FCF

Vitellogenin

Bombus ignitus

130,704

1,772

0.019752

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Hymenoptera", "Apocrita", "Aculeata", "Apoidea", "Apidae", "Bombus", "Bombus" ]

2018_11

2018-09-05T15:57:56.000Z

ndavey

UniRef100_C4PB33

UniRef90_A0A6P3TLJ9

UniRef50_A0A6P3DVD4

MWLPLTVLLLAGIVSADYDHGWHVNNEYIYLVRSRTLVNLNELSDQHTGILMKALLTIQVKDPQMLTAKVSQSQYARILKSLPEGWDAEISDQMLELRDMPLSGKPFNIKLKHGVIRDIIVDRTIPTWEVNILKSIVSQLQVDSLGENAIRTSEMQIPTDEHPYGMFRAMEDSVGGKCEVLYDITPLPEQNVYVQPELVPVPDLKREGQYIDIRKSKNFNKCDQRMNYQFGITGNKYWEAGSNKNGKFFSQSAMSRIIISGTLKSYTIQSAVTTNIMYISPRFYDHEHGMVTSRMNLTLAAVKKITNPLPKPNSPESTGN...

1

[ "DP02330r001" ]

[ 361 ]

[ 395 ]

[ 35 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006204" ]

[ "22573762" ]

[ "pmid" ]

[ "Norman Davey" ]

[]

[ "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "2.30.230.10", "1.25.10.20", "PF00094", "PF01347", "PF09172" ]

[ "Lipovitellin; beta-sheet shell regions, chain A", "Vitellinogen, superhelical", "von Willebrand factor type D domain", "Lipoprotein amino terminal region", "Vitellinogen, open beta-sheet" ]

5

[]

[ 361 ]

[ 395 ]

[ "D" ]

7

DP02331

O17428

UPI000008083D

Vitellogenin

Pimpla nipponica

67,752

1,807

0.023243

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Hymenoptera", "Apocrita", "Parasitoida", "Ichneumonoidea", "Ichneumonidae", "Pimplinae", "Pimplini", "Pimpla" ]

2018_11

2018-09-05T15:58:53.000Z

ndavey

UniRef100_O17428

UniRef90_O17428

UniRef50_O17428

MWCPLFLVLLAGAATAEHLQAWKTDTEYQYAVRGRTLSALHDVADQYSGIIMRALLTIQPKSDGTLEAKVTKARYAQIHTKLPGGWNSEIPDHKLEMKQFPMSEKVFEIKMKHGVVRDLIVDKDVPTWEVNVLKSIVSQLQVDTQGENLMASKYNQEPEDEGVTAMFKTMEDTVGGRCEVLYDINPLPEFVLQKRPELVPMPDIRGDGEIIDIVKTKNYSNCEQRSGYHFGIPGTNKWEPSSGASGNFLSRSSVSRVIVTGNLKSFTIQSSVSTNKVILSPNFHENRKGMVSSRVNVTLVKIGAPSTGDWSTPANPESTG...

1

[ "DP02331r001" ]

[ 356 ]

[ 397 ]

[ 42 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006204" ]

[ "22573762" ]

[ "pmid" ]

[ "Norman Davey" ]

[]

[ "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "1.25.10.20", "2.30.230.10", "PF00094", "PF01347", "PF09172" ]

[ "Vitellinogen, superhelical", "Lipovitellin; beta-sheet shell regions, chain A", "von Willebrand factor type D domain", "Lipoprotein amino terminal region", "Vitellinogen, open beta-sheet" ]

5

[ "Vg" ]

[ 356 ]

[ 397 ]

[ "D" ]

5

DP02333

P13861

UPI000012DC0D

cAMP-dependent protein kinase type II-alpha regulatory subunit

Homo sapiens

9,606

404

0.116337

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2018_11

2018-09-05T16:43:27.000Z

ndavey

UniRef100_P13861

UniRef90_P13861

UniRef50_P13861

MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDG...

2

[ "DP02333r001", "DP02333r002" ]

[ 44, 44 ]

[ 90, 90 ]

[ 47, 47 ]

[ "disorder", "flexible linker" ]

[ "IDPO:0000002", "IDPO:0000033" ]

[ "Structural state", "Disorder function" ]

[ "ECO:0006224", "ECO:0006208" ]

[ "24192038", "24192038" ]

[ "pmid", "pmid" ]

[ "Norman Davey", "Norman Davey" ]

[]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "2.60.120.10", "2.60.120.10", "1.20.890.10", "PF00027", "PF00027", "PF02197" ]

[ "Jelly Rolls", "Jelly Rolls", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain", "Cyclic nucleotide-binding domain", "Cyclic nucleotide-binding domain", "Regulatory subunit of type II PKA R-subunit" ]

6

[ "PKR2", "PRKAR2", "PRKAR2A" ]

[ 44 ]

[ 90 ]

[ "D" ]

2

DP02334

Q98148

UPI0000039921

Kaposi's sarcoma-associated herpes-like virus ORF73 homolog

Human herpesvirus 8

37,296

1,162

0.378657

[ "Viral proteins" ]

[ "Viruses", "Duplodnaviria", "Heunggongvirae", "Peploviricota", "Herviviricetes", "Herpesvirales", "Herpesviridae", "Gammaherpesvirinae", "Rhadinovirus" ]

2018_11

2018-09-08T15:40:08.000Z

bmesza

UniRef100_Q98148

UniRef90_Q9QR71

UniRef50_Q9QR71

MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSIDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQ...

7

[ "DP02334r001", "DP02334r003", "DP02334r004", "DP02334r005", "DP02334r006", "DP02334r007", "DP02334r015" ]

[ 1110, 1133, 1133, 745, 620, 325, 1133 ]

[ 1162, 1144, 1144, 925, 723, 426, 1144 ]

[ 53, 12, 12, 181, 104, 102, 12 ]

[ "disorder", "disorder to order", "protein binding", "disorder", "disorder", "disorder", "viral life cycle" ]

[ "IDPO:0000002", "IDPO:0000011", "GO:0005515", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0019058" ]

[ "Structural state", "Structural transition", "Molecular function", "Structural state", "Structural state", "Structural state", "Biological process" ]

[ "ECO:0006165", "ECO:0006165", "ECO:0006165", "ECO:0007759", "ECO:0007759", "ECO:0007759", "ECO:0006165" ]

[ "27291650", "27291650", "27291650", "https://mobidb.org/Q98148", "https://mobidb.org/Q98148", "https://mobidb.org/Q98148", "27291650" ]

[ "pmid", "pmid", "pmid", "mobidb", "mobidb", "mobidb", "pmid" ]

[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Alex Monzon", "Alex Monzon", "Alex Monzon", "Victoria Nugnes" ]

[ "BMRB:26042", "PDB:2ND0" ]

[ "gene3D", "pfam" ]

[ "3.30.70.390", "PF21501" ]

[ "Epstein Barr virus nuclear antigen-1, DNA-binding domain", "Protein LANA1-like, DNA-binding domain" ]

2

[]

[ 325, 620, 745, 1110, 1133, 1145 ]

[ 426, 723, 925, 1132, 1144, 1162 ]

[ "D", "D", "D", "D", "T", "D" ]

1

DP02337

O46385

UPI0001A61553

Supervillin

Bos taurus

9,913

2,194

0.15588

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Laurasiatheria", "Artiodactyla", "Ruminantia", "Pecora", "Bovidae", "Bovinae", "Bos" ]

2019_09

2019-09-05T08:14:43.114Z

fquaglia

UniRef100_O46385

UniRef90_O46385

UniRef50_O95425-3

MKRKERIARRLEGIETDTQPILLQSCTGLVTHRLLEEDTPRYMRATDPASPHIGRSNEEEETSDSSLEKQTRSKQCTETSGIHADSPYSSGIMDTQSLESKAERIARYKAERRRQLAEKYGLTLDPEADSETPSRYSRSRKDPEAAEKRGVRSERSAESSRDAGSSYSRTELSGLRTCVAESKDYGLHRSDGVSDTEVLLNAENQRRGQEPSATGLARDLPLAGEVSSSFSFSGRDSALGEVPRSPKAVHSLPSPSPGQPASPSHSTSDLPLPAEARASIGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVREESAR...

4

[ "DP02337r002", "DP02337r003", "DP02337r004", "DP02337r005" ]

[ 1, 11, 11, 1 ]

[ 342, 174, 174, 342 ]

[ 342, 164, 164, 342 ]

[ "disorder", "protein binding", "protein binding", "molecular adaptor activity" ]

[ "IDPO:0000002", "GO:0005515", "GO:0005515", "GO:0060090" ]

[ "Structural state", "Molecular function", "Molecular function", "Molecular function" ]

[ "ECO:0006204", "ECO:0005805", "ECO:0001164", "ECO:0006323" ]

[ "23075227", "12917436", "12917436", "12917436" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Edoardo Salladini", "Edoardo Salladini", "Federica Quaglia" ]

[]

[ "gene3D", "gene3D", "gene3D", "gene3D", "gene3D", "gene3D", "pfam", "pfam" ]

[ "3.40.20.10", "3.40.20.10", "1.10.950.10", "3.40.20.10", "3.40.20.10", "3.40.20.10", "PF00626", "PF02209" ]

[ "Severin", "Severin", "Villin headpiece domain", "Severin", "Severin", "Severin", "Gelsolin repeat", "Villin headpiece domain" ]

8

[ "SVIL" ]

[ 1 ]

[ 342 ]

[ "D" ]

6

DP02338

O60701

UPI0000001075

UDP-glucose 6-dehydrogenase

Homo sapiens

9,606

494

0.060729

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2019_09

2019-09-05T15:36:17.486Z

fquaglia

UniRef100_O60701

UniRef90_O60701

UniRef50_O60701

MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIID...

2

[ "DP02338r002", "DP02338r003" ]

[ 465, 465 ]

[ 494, 494 ]

[ 30, 30 ]

[ "flexible C-terminal tail", "disorder" ]

[ "IDPO:0000031", "IDPO:0000002" ]

[ "Disorder function", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "30420606", "30420606" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Victoria Nugnes" ]

[ "PDB:5VR8" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "3.40.50.720", "3.40.50.720", "1.20.5.100", "PF00984", "PF03720", "PF03721" ]

[ "NAD(P)-binding Rossmann-like Domain", "NAD(P)-binding Rossmann-like Domain", "Cytochrome c1, transmembrane anchor, C-terminal", "UDP-glucose/GDP-mannose dehydrogenase family, central domain", "UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain", "UDP-glucose/GDP-mannose dehydrogenase family...

6

[ "UGDH" ]

[ 465 ]

[ 494 ]

[ "D" ]

3

DP02341

A0A178W0D3

UPI0007E24479

Plastid transcriptionally active 4

Arabidopsis thaliana

3,702

259

0.150579

[]

[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "eudicotyledons", "Gunneridae", "Pentapetalae", "rosids", "malvids", "Brassicales", "Brassicaceae", "Camelineae", "Arabidopsis" ]

2019_09

2019-09-09T16:26:28.510Z

ahatos

UniRef100_O80796

UniRef90_O80796

UniRef50_O80796

MNLFERFSRVVKSYANALISSFEDPEKILEQTVIEMNSDLTKMRQATAQVLASQKQLQNKYKAAQQSSDDWYKRAQLALAKGDEDLAREALKRRKSFADNATALKTQLDQQKGVVDNLVSNTRLLESKIQEAKAKKDTLLARARTAKTATKVQEMIGTVNTSGALSAFEKMEEKVMAMESEADALTQIGTDELEGKFQMLETSSVDDDLADLKKELSGSSKKGELPPGRSTVAASTRYPFKDSEIENELNELRRKANDF

3

[ "DP02341r001", "DP02341r002", "DP02341r003" ]

[ 221, 221, 221 ]

[ 259, 259, 259 ]

[ 39, 39, 39 ]

[ "disorder", "disorder", "protein folding chaperone" ]

[ "IDPO:0000002", "IDPO:0000002", "GO:0044183" ]

[ "Structural state", "Structural state", "Molecular function" ]

[ "ECO:0006204", "ECO:0006317", "ECO:0006317" ]

[ "27208228", "27208228", "27208228" ]

[ "pmid", "pmid", "pmid" ]

[ "Beata Szabo", "Beata Szabo", "Beata Szabo" ]

[]

[ "pfam" ]

[ "PF04012" ]

[ "PspA/IM30 family" ]

1

[ "At1g65260", "PTAC4", "T8F5.2", "T8F5_2", "VIPP1" ]

[ 221 ]

[ 259 ]

[ "D" ]

3

DP02342

P06837

UPI00000011D6

Neuromodulin

Mus musculus

10,090

227

1

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2023_12

2019-11-11T11:20:25.539Z

fquaglia

UniRef100_P06837

UniRef90_P07936

UniRef50_P07936

MLCCMRRTKQVEKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAPAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAATKAAQPPTETAESSQAEEEKDAVDEAKPKESARQDEGKEDPEADQEHA

7

[ "DP02342r003", "DP02342r006", "DP02342r007", "DP02342r009", "DP02342r010", "DP02342r011", "DP02342r013" ]

[ 1, 34, 34, 1, 34, 34, 34 ]

[ 227, 57, 57, 227, 57, 57, 57 ]

[ 227, 24, 24, 227, 24, 24, 24 ]

[ "pre-molten globule", "localization", "molecular function regulator", "pre-molten globule", "protein binding", "protein binding", "pre-molten globule to order" ]

[ "IDPO:0000004", "GO:0051179", "GO:0098772", "IDPO:0000004", "GO:0005515", "GO:0005515", "IDPO:0000013" ]

[ "Structural state", "Biological process", "Molecular function", "Structural state", "Molecular function", "Molecular function", "Structural transition" ]

[ "ECO:0006204", "ECO:0005647", "ECO:0005647", "ECO:0006165", "ECO:0005647", "ECO:0005670", "ECO:0005670" ]

[ "23462742", "23462742", "23462742", "23462742", "23462742", "23462742", "23462742" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Bálint Mészáros", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Bálint Mészáros", "Bálint Mészáros", "Bálint Mészáros" ]

[ "PDB:4E53" ]

[ "pfam", "pfam", "pfam" ]

[ "PF00612", "PF06614", "PF10580" ]

[ "IQ calmodulin-binding motif", "Neuromodulin", "Gap junction protein N-terminal region" ]

3

[ "Basp2", "Gap43" ]

[ 1, 34, 58 ]

[ 33, 57, 227 ]

[ "D", "T", "D" ]

7

DP02346

Q9BTL3

UPI00000467E0

RNA guanine-N7 methyltransferase activating subunit

Homo sapiens

9,606

118

0.372881

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-11-12T14:41:04.160Z

fquaglia

UniRef100_Q9BTL3

UniRef90_Q9BTL3

UniRef50_Q9BTL3

MTDTAEAVPKFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY

4

[ "DP02346r001", "DP02346r002", "DP02346r003", "DP02346r004" ]

[ 2, 2, 2, 2 ]

[ 45, 45, 45, 45 ]

[ 44, 44, 44, 44 ]

[ "disorder", "disorder to order", "protein binding", "molecular function activator activity" ]

[ "IDPO:0000002", "IDPO:0000011", "GO:0005515", "GO:0140677" ]

[ "Structural state", "Structural transition", "Molecular function", "Molecular function" ]

[ "ECO:0006165", "ECO:0006165", "ECO:0006165", "ECO:0006165" ]

[ "27422871", "27422871", "27422871", "27422871" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5E8J" ]

[ "pfam" ]

[ "PF15320" ]

[ "mRNA cap methylation, RNMT-activating mini protein" ]

1

[ "C15orf18", "FAM103A1", "RAMAC", "RAMMET" ]

[ 2 ]

[ 45 ]

[ "T" ]

8

DP02348

Q8N5F7

UPI000004A07B

NF-kappa-B-activating protein

Homo sapiens

9,606

415

0.927711

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_06

2019-11-13T09:55:32.480Z

fquaglia

UniRef100_Q8N5F7

UniRef90_Q8N5F7

UniRef50_Q8N5F7

MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAA...

5

[ "DP02348r007", "DP02348r008", "DP02348r009", "DP02348r010", "DP02348r011" ]

[ 1, 1, 359, 1, 359 ]

[ 328, 328, 415, 328, 415 ]

[ 328, 328, 57, 328, 57 ]

[ "disorder", "disorder", "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006224", "ECO:0006208", "ECO:0006208", "ECO:0006208", "ECO:0006208" ]

[ "36867703", "30705154", "30705154", "35705093", "35705093" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]

[ "EMDB:16452", "EMDB:32321", "EMDB:4525", "PDB:6QDV", "PDB:7W5B", "PDB:8C6J" ]

[ "pfam", "pfam" ]

[ "PF06047", "PF15692" ]

[ "NF-kappa-B-activating protein C-terminal domain", "NF-kappa-B-activating protein" ]

2

[ "NKAP" ]

[ 1, 359 ]

[ 328, 415 ]

[ "D", "D" ]

4

DP02349

P51825

UPI0000125658

AF4/FMR2 family member 1

Homo sapiens

9,606

1,210

0.019008

[ "Cancer-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2022_06

2019-11-13T15:16:15.476Z

fquaglia

UniRef100_P51825

UniRef90_P51825

UniRef50_P51825

MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQ...

1

[ "DP02349r002" ]

[ 738 ]

[ 760 ]

[ 23 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006204" ]

[ "23260655" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:2LM0" ]

[ "pfam", "pfam", "pfam" ]

[ "PF05110", "PF18875", "PF18876" ]

[ "AF-4 proto-oncoprotein N-terminal region", "AF4 interaction motif", "AFF4, C-terminal homology domain" ]

3

[ "AF4", "AFF1", "FEL", "MLLT2", "PBM1" ]

[ 738 ]

[ 760 ]

[ "D" ]

4

DP02353

P0DMV9

UPI0000000C40

Heat shock 70 kDa protein 1B

Homo sapiens

9,606

641

0.121685

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-11-13T16:52:59.413Z

fquaglia

UniRef100_P0DMV8

UniRef90_P0DMV8

UniRef50_P0DMV8

MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKA...

1

[ "DP02353r001" ]

[ 229 ]

[ 306 ]

[ 78 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "10216320" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[]

[ "gene3D", "gene3D", "pfam" ]

[ "G3DSA:2.60.34.10", "G3DSA:1.20.1270.10", "PF00012" ]

[ "Substrate Binding Domain Of DNAk; Chain A, domain 1", "G3DSA:1.20.1270.10", "Hsp70 protein" ]

3

[ "HSP72", "HSPA1B" ]

[ 229 ]

[ 306 ]

[ "D" ]

6

DP02356

P78794

UPI00001690EC

Pre-mRNA-splicing factor cwf15

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

284,812

265

0.660377

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Taphrinomycotina", "Schizosaccharomycetes", "Schizosaccharomycetales", "Schizosaccharomycetaceae", "Schizosaccharomyces" ]

2021_06

2019-11-14T16:58:41.199Z

fquaglia

UniRef100_P78794

UniRef90_P78794

UniRef50_P78794

MTTAHRPQFDPARGHSEMAPTRITSSRALPAHLKLKYRQESQGTEEEVRKQDLREALLRAEAAHFATQEHGASSEEVSQNSKLIEGFTSPSTDDKPNNDVEVDYQELLRQTLEADEDASDSDDSVDSSNKNSEVSIKRRKTESNSQESVDSSNSESSDEESDSEDETQQLLRELENIKQERKREQMLQEEKNRALEQEKREREIAFGNELLNKASSGSFQVKRRWDEDVVFRNTHKGVDDTPRPGFVNDMLRSEFHKKFLARFVD

2

[ "DP02356r001", "DP02356r002" ]

[ 1, 71 ]

[ 23, 222 ]

[ 23, 152 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006224", "ECO:0006224" ]

[ "26292707", "26292707" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3JB9" ]

[ "pfam" ]

[ "PF04889" ]

[ "Cwf15/Cwc15 cell cycle control protein" ]

1

[ "SPBC337.06c", "cwf15" ]

[ 1, 71 ]

[ 23, 222 ]

[ "D", "D" ]

7

DP02357

O14187

UPI000006A413

Pre-mRNA-splicing factor spp42

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

284,812

2,363

0.154888

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Taphrinomycotina", "Schizosaccharomycetes", "Schizosaccharomycetales", "Schizosaccharomycetaceae", "Schizosaccharomyces" ]

2020_12

2019-11-15T11:21:40.948Z

fquaglia

UniRef100_O14187

UniRef90_O14187

UniRef50_O14187

MASLPPGNPPPPPPPPGFEPPSQPPPPPPPGYVKKRKNKTPAQSGNLEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYKDEAPEMEDWNEFNDIYK...

2

[ "DP02357r001", "DP02357r002" ]

[ 1, 2044 ]

[ 46, 2363 ]

[ 46, 320 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0001232", "ECO:0001232" ]

[ "26292707", "26292707" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3JB9" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.20.58.1750", "G3DSA:3.30.420.230", "G3DSA:1.20.80.40", "PF01398", "PF08082", "PF08083", "PF08084", "PF10596", "PF10597", "PF10598", "PF12134" ]

[ "G3DSA:1.20.58.1750", "G3DSA:3.30.420.230", "G3DSA:1.20.80.40", "JAB1/Mov34/MPN/PAD-1 ubiquitin protease", "PRO8NT (NUC069), PrP8 N-terminal domain", "PROCN (NUC071) domain", "PROCT (NUC072) domain", "U6-snRNA interacting domain of PrP8", "U5-snRNA binding site 2 of PrP8", "RNA recognition motif o...

11

[ "SPAC4F8.12c", "cwf6", "spp42" ]

[ 1, 2044 ]

[ 46, 2363 ]

[ "D", "D" ]

1

DP02360

O14810

UPI0000127BB3

Complexin-1

Homo sapiens

9,606

134

0.074627

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-11-21T16:26:12.711Z

fquaglia

UniRef100_O14810

UniRef90_O14810

UniRef50_O14810

MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQDMLKK

1

[ "DP02360r001" ]

[ 74 ]

[ 83 ]

[ 10 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "21785414" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3RK3", "PDB:3RL0" ]

[ "pfam" ]

[ "PF05835" ]

[ "Synaphin protein" ]

1

[ "CPLX1" ]

[ 74 ]

[ 83 ]

[ "D" ]

1

DP02361

O95429

UPI0000126769

BAG family molecular chaperone regulator 4

Homo sapiens

9,606

457

0.043764

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-11-21T16:55:59.041Z

fquaglia

UniRef100_O95429

UniRef90_O95429

UniRef50_O95429

MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPLYPLRPEPPQPPISWRVRGGGPAETTWLGEGGGGDGYYPSGGAWPEPGRAGGSHQEQPPYPSYNSNYWNSTARSRAPYPSTYPVRPELQGQSLNSYTNGAYGPTYPPGPGANTASYSGAYYAPGYTQTSYSTEVPSTYRSSGNSPTPVSRWIYPQQDCQTEAPPLRGQVPGYPPSQNPGMTLPHYPYGDGNRSVPQSGPTVRPQEDAWASPGAYGMGGRYPWPSSAPSAPPGNLYMTESTSPWPSSGSPQSPPSPPVQQPKDSSYPYSQSDQSMNRHNFPCSVHQ...

1

[ "DP02361r001" ]

[ 357 ]

[ 376 ]

[ 20 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006165" ]

[ "14759524" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1M7K" ]

[ "gene3D", "pfam" ]

[ "G3DSA:1.20.58.120", "PF02179" ]

[ "BAG domain", "BAG domain" ]

2

[ "BAG4", "SODD" ]

[ 357 ]

[ 376 ]

[ "D" ]

5

DP02364

Q9H6Z4-3

UPI00002031A7

Isoform 3 of Ran-binding protein 3

Homo sapiens

9,606

499

0.03006

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-11-22T10:15:21.086Z

fquaglia

MADLANEEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEK...

1

[ "DP02364r001" ]

[ 31 ]

[ 45 ]

[ 15 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "28760339" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5XZX" ]

[]

0

[ "RANBP3" ]

[ 31 ]

[ 45 ]

[ "D" ]

4

DP02365

Q13464

UPI000006F0A4

Rho-associated protein kinase 1

Homo sapiens

9,606

1,354

0.014032

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-11-22T14:56:21.953Z

fquaglia

UniRef100_Q13464

UniRef90_Q13464

UniRef50_Q13464

MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDR...

1

[ "DP02365r001" ]

[ 895 ]

[ 913 ]

[ 19 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27758857" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5F5P" ]

[ "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:2.30.29.30", "PF00069", "PF08912", "PF25346" ]

[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "Protein kinase domain", "Rho Binding", "MRCK kinase PH domain" ]

4

[ "ROCK1" ]

[ 895 ]

[ 913 ]

[ "D" ]

2

DP02369

Q00780

UPI0000161D30

Collagen alpha-1(VIII) chain

Mus musculus

10,090

744

0.057796

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2020_12

2019-11-26T15:24:09.528Z

fquaglia

UniRef100_Q00780

UniRef90_P27658

UniRef50_P27658

MAVPPRPLQLLGILFIISLNSVRLIQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIPPVPRMGKEVVPKKGKGEVPLASLRGEQGPRGEPGPRGPPGPPGLPGHGMPGIKGKPGPQGYPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPGVGKPG...

1

[ "DP02369r001" ]

[ 570 ]

[ 612 ]

[ 43 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "12782141" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1O91" ]

[ "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:2.60.120.40", "PF00386", "PF01391", "PF01391" ]

[ "G3DSA:2.60.120.40", "C1q domain", "Collagen triple helix repeat (20 copies)", "Collagen triple helix repeat (20 copies)" ]

4

[ "Col8a1" ]

[ 570 ]

[ 612 ]

[ "D" ]

2

DP02373

Q92837

UPI0000527ED8

Proto-oncogene FRAT1

Homo sapiens

9,606

279

0.910394

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-11-27T14:51:08.260Z

fquaglia

UniRef100_Q92837

UniRef90_Q92837

UniRef50_Q92837

MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS

3

[ "DP02373r001", "DP02373r002", "DP02373r003" ]

[ 1, 224, 188 ]

[ 198, 279, 226 ]

[ 198, 56, 39 ]

[ "disorder", "disorder", "molecular function inhibitor activity" ]

[ "IDPO:0000002", "IDPO:0000002", "GO:0140678" ]

[ "Structural state", "Structural state", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0007689" ]

[ "29057057", "29057057", "10481074" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5OY4" ]

[ "pfam" ]

[ "PF05350" ]

[ "Glycogen synthase kinase-3 binding" ]

1

[ "FRAT1" ]

[ 1, 199, 224 ]

[ 198, 223, 279 ]

[ "D", "F", "D" ]

2

DP02375

Q96T58

UPI000006FF0C

Msx2-interacting protein

Homo sapiens

9,606

3,664

0.006823

[ "Cancer-related proteins", "NDDs-related proteins", "RNA-binding proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-11-27T16:05:24.273Z

fquaglia

UniRef100_Q96T58

UniRef90_Q96T58

UniRef50_Q96T58

MVRETRHLWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGSEGGVAAFVDFVDIKSAQKAHNSVNKMGDRDLRTDYNEPGTIPSAARGLDDTVSIASRSREVSGFRGGGGGPAYGPPPSLHAREGRYERRLDGASDNRERAYEHSAYGHHERGTGGFDRTRHYDQDYYRDPRERTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSDDSPARSVQSAAVPAPTS...

1

[ "DP02375r001" ]

[ 3470 ]

[ 3494 ]

[ 25 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "12897056" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1OW1" ]

[ "gene3D", "gene3D", "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:2.40.290.10", "PF00076", "PF00076", "PF00076", "PF00076", "PF07744", "PF20808", "PF20809", "PF20810" ]

[ "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:3.30.70.330", "G3DSA:2.40.290.10", "RNA recognition motif", "RNA recognition motif", "RNA recognition motif", "RNA recognition motif", "SPOC domain", "Msx2-interacting protein, RAM7 domain", "Msx2-interacting protein, MID do...

13

[ "KIAA0929", "MINT", "SHARP", "SPEN" ]

[ 3470 ]

[ 3494 ]

[ "D" ]

2

DP02376

Q4ACU6

UPI0001529A70

SH3 and multiple ankyrin repeat domains protein 3

Mus musculus

10,090

1,730

0.635838

[ "NDDs-related proteins", "Condensates-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2023_06

2019-11-27T16:14:39.228Z

fquaglia

UniRef100_Q4ACU6

UniRef90_Q4ACU6

UniRef50_Q4ACU6

MDGPGASAVVVRVGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAF...

5

[ "DP02376r001", "DP02376r002", "DP02376r003", "DP02376r004", "DP02376r005" ]

[ 588, 377, 666, 1324, 1427 ]

[ 600, 532, 1293, 1399, 1653 ]

[ 13, 156, 628, 76, 227 ]

[ "disorder", "disorder", "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0000302", "ECO:0000302", "ECO:0000302", "ECO:0000302" ]

[ "21626699", "33235361", "33235361", "33235361", "33235361" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]

[ "PDB:3O5N" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.10.150.50", "G3DSA:2.30.42.10", "G3DSA:1.25.40.20", "PF00536", "PF07653", "PF12796", "PF12796", "PF17820" ]

[ "Transcription Factor, Ets-1", "G3DSA:2.30.42.10", "Ankyrin repeat-containing domain", "SAM domain (Sterile alpha motif)", "Variant SH3 domain", "Ankyrin repeats (3 copies)", "Ankyrin repeats (3 copies)", "PDZ domain" ]

8

[ "Kiaa1650", "Prosap2", "Shank3" ]

[ 377, 588, 666, 1324, 1427 ]

[ 532, 600, 1293, 1399, 1653 ]

[ "D", "D", "D", "D", "D" ]

9

DP02377

Q9GRZ3

UPI00000612E3

Lysine-specific demethylase 9

Caenorhabditis elegans

6,239

1,641

0.035954

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Nematoda", "Chromadorea", "Rhabditida", "Rhabditina", "Rhabditomorpha", "Rhabditoidea", "Rhabditidae", "Peloderinae", "Caenorhabditis" ]

2023_12

2019-11-27T16:43:03.204Z

fquaglia

UniRef100_Q9GRZ3

UniRef90_Q9GRZ3

UniRef50_Q9GRZ3

MRSTTFDKNSGAPEEPRRPRGPRTPDGEPTEANERPCSSSSSLSNDSFVPAPQGPQNGHTSSSHDNDYSEYRPRRGPKTPPLPPPDEPVKQQQQQQPIVAPYSYYPTYGSSTGYPYPYPTMMMPQQGIPGPSQHPATPSYYIQHPPPPSMSNGAPYYPHMNPSPYYQPRPNYVTQPPAPIIPPPQPPVMTASAAAAAYRDRLPPPPPKPPMPDLRTKEPIGIRSWNGSGIPPPPILPPVACLSSTMSPGMLRSPVPRERFNSVESNGSFSLHPPPPVPPPAKKPLNMDVRELLNGAHQTTVESVKKDPPAPQPRPRPIPV...

2

[ "DP02377r001", "DP02377r002" ]

[ 1420, 1458 ]

[ 1441, 1494 ]

[ 22, 37 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "28867287", "28867287" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5UQD" ]

[]

0

[ "Y59A8B.1", "dpy-21" ]

[ 1420, 1458 ]

[ 1441, 1494 ]

[ "D", "D" ]

2

DP02378

Q09260

UPI000002AD0D

Protein lag-3

Caenorhabditis elegans

6,239

490

0.036735

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Nematoda", "Chromadorea", "Rhabditida", "Rhabditina", "Rhabditomorpha", "Rhabditoidea", "Rhabditidae", "Peloderinae", "Caenorhabditis" ]

2020_12

2019-11-27T16:54:26.655Z

fquaglia

UniRef100_Q09260

UniRef90_Q09260

UniRef50_Q09260

MDDLSEFFVIEEMFISEPSVAGMKPSTSKTTHSPPPEEPTAPFVNDNLPNPEDEPTIGDLNAFHSGEELHRQRSELARANYEKARPEMIANQRAVTAHLFNRYTEDEERKRVEQQKNKEAMNASTSAPTSSRNGGQSVENRKRRNDVVVAPPTSEEEWKRAQQQHWMGQQQPQMQFQMQQQYHSQQQQYIMMQQQHHHMTGMQQIHHQMPSTSSADSIRSVPTPASSMHQPSPAEMRNGCGMSRNATMDMTCSPMSGGQPIVDENNLAVPEGEWFDKLALAVAEQYNVDTILGPDTYDTFLAELDFSSSESPTKQSPMEM...

1

[ "DP02378r001" ]

[ 115 ]

[ 132 ]

[ 18 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "16530045" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:2FO1" ]

[ "pfam" ]

[ "PF11498" ]

[ "Transcriptional activator LAG-3" ]

1

[ "C32A3.1", "lag-3", "sel-8" ]

[ 115 ]

[ 132 ]

[ "D" ]

9

DP02380

O23661

UPI00000AADC5

Auxin response factor 3

Arabidopsis thaliana

3,702

608

0.340461

[]

[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "eudicotyledons", "Gunneridae", "Pentapetalae", "rosids", "malvids", "Brassicales", "Brassicaceae", "Camelineae", "Arabidopsis" ]

2021_06

2019-11-28T07:58:17.985Z

rpancsa

UniRef100_O23661

UniRef90_O23661

UniRef50_O23661

MGGLIDLNVMETEEDETQTQTPSSASGSVSPTSSSSASVSVVSSNSAGGGVCLELWHACAGPLISLPKRGSLVLYFPQGHLEQAPDFSAAIYGLPPHVFCRILDVKLHAETTTDEVYAQVSLLPESEDIERKVREGIIDVDGGEEDYEVLKRSNTPHMFCKTLTASDTSTHGGFSVPRRAAEDCFPPLDYSQPRPSQELLARDLHGLEWRFRHIYRGQPRRHLLTTGWSAFVNKKKLVSGDAVLFLRGDDGKLRLGVRRASQIEGTAALSAQYNQNMNHNNFSEVAHAISTHSVFSISYNPKASWSNFIIPAPKFLKVVD...

4

[ "DP02380r001", "DP02380r002", "DP02380r003", "DP02380r004" ]

[ 388, 388, 388, 388 ]

[ 594, 594, 594, 594 ]

[ 207, 207, 207, 207 ]

[ "disorder", "molecular function activator activity", "small molecule binding", "protein binding" ]

[ "IDPO:0000002", "GO:0140677", "GO:0036094", "GO:0005515" ]

[ "Structural state", "Molecular function", "Molecular function", "Molecular function" ]

[ "ECO:0006200", "ECO:0005805", "ECO:0000315", "ECO:0005805" ]

[ "30202032", "30202032", "30202032", "30202032" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Rita Pancsa", "Edoardo Salladini", "Edoardo Salladini", "Edoardo Salladini" ]

[]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:2.40.330.10", "PF02362", "PF06507" ]

[ "DNA-binding pseudobarrel domain", "B3 DNA binding domain", "Auxin response factor ancillary domain" ]

3

[ "ARF3", "At2g33860", "ETT", "T1B8.30" ]

[ 388 ]

[ 594 ]

[ "D" ]

8

DP02381

O60706-2

UPI000013D13F

Isoform SUR2B of ATP-binding cassette sub-family C member 9

Homo sapiens

9,606

1,549

0.03357

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-11-28T09:28:19.688Z

rpancsa

MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISG...

6

[ "DP02381r001", "DP02381r002", "DP02381r003", "DP02381r004", "DP02381r005", "DP02381r006" ]

[ 618, 618, 618, 618, 618, 618 ]

[ 669, 669, 669, 669, 669, 669 ]

[ 52, 52, 52, 52, 52, 52 ]

[ "disorder", "disorder", "disorder", "phosphorylation display site", "molecular function regulator", "protein binding" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000045", "GO:0098772", "GO:0005515" ]

[ "Structural state", "Structural state", "Structural state", "Disorder function", "Molecular function", "Molecular function" ]

[ "ECO:0006165", "ECO:0007680", "ECO:0006200", "ECO:0006165", "ECO:0006165", "ECO:0006165" ]

[ "30273482", "30273482", "30273482", "30273482", "30273482", "30273482" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa" ]

[]

0

[ "ABCC9", "SUR2" ]

[ 618 ]

[ 669 ]

[ "D" ]

7

DP02383

P08631

UPI000053F913

Tyrosine-protein kinase HCK

Homo sapiens

9,606

526

0.148289

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-11-28T11:41:21.870Z

rpancsa

UniRef100_P08631

UniRef90_P08631

UniRef50_P08631

MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIKPGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKL...

6

[ "DP02383r001", "DP02383r002", "DP02383r003", "DP02383r004", "DP02383r005", "DP02383r006" ]

[ 2, 2, 2, 2, 2, 2 ]

[ 79, 79, 6, 21, 79, 79 ]

[ 78, 78, 5, 20, 78, 78 ]

[ "disorder", "localization", "myristoylation display site", "localization", "localization", "lipid binding" ]

[ "IDPO:0000002", "GO:0051179", "IDPO:0000043", "GO:0051179", "GO:0051179", "GO:0008289" ]

[ "Structural state", "Biological process", "Disorder function", "Biological process", "Biological process", "Molecular function" ]

[ "ECO:0006165", "ECO:0006218", "ECO:0006218", "ECO:0006218", "ECO:0006165", "ECO:0006165" ]

[ "30284668", "30284668", "30284668", "30284668", "31877324", "31877324" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa", "Rita Pancsa" ]

[ "BMRB:27554" ]

[ "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:3.30.505.10", "PF00017", "PF00018", "PF07714" ]

[ "SH2 domain", "SH2 domain", "SH3 domain", "Protein tyrosine and serine/threonine kinase" ]

4

[ "HCK" ]

[ 2 ]

[ 79 ]

[ "D" ]

8

DP02384

P82804

UPI0000124769

Partner of Y14 and mago

Drosophila melanogaster

7,227

207

0.125604

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]

2020_12

2019-11-29T09:27:17.655Z

fquaglia

UniRef100_P82804

UniRef90_P82804

UniRef50_P82804

MSTYLQSSEGKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPLLAAESKKEREKQERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQQQQPSGSRDINSISKTLEDTLKLDAAQEVVDPAKQLKKLRKKIREIEQIESRIQAGEQKKLDKDQLDKVKKKSEILRQIKDLESTPRS

1

[ "DP02384r001" ]

[ 33 ]

[ 58 ]

[ 26 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "14968132" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1RK8" ]

[ "pfam" ]

[ "PF09282" ]

[ "Mago binding" ]

1

[ "CG30176", "Pym", "wibg" ]

[ 33 ]

[ 58 ]

[ "D" ]

8

DP02386

Q9NYB9

UPI0000071313

Abl interactor 2

Homo sapiens

9,606

513

0.697856

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_06

2019-11-29T10:00:53.364Z

fquaglia

UniRef100_Q9NYB9

UniRef90_Q9NYB9

UniRef50_Q9NYB9

MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPNAAA...

1

[ "DP02386r001" ]

[ 156 ]

[ 513 ]

[ 358 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "24439376" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:4N78" ]

[ "pfam", "pfam" ]

[ "PF00018", "PF07815" ]

[ "SH3 domain", "Abl-interactor HHR" ]

2

[ "ABI2", "ARGBPIA" ]

[ 156 ]

[ 513 ]

[ "D" ]

4

DP02387

P70429

UPI00000278C1

Ena/VASP-like protein

Mus musculus

10,090

414

0.041063

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2020_12

2019-11-29T10:16:28.950Z

fquaglia

UniRef100_P70429

UniRef90_P70429

UniRef50_Q9UI08

MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASTTLSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAG...

1

[ "DP02387r001" ]

[ 114 ]

[ 130 ]

[ 17 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "10404224" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1QC6" ]

[ "gene3D", "gene3D", "pfam", "pfam" ]

[ "G3DSA:2.30.29.30", "G3DSA:1.20.5.1160", "PF00568", "PF08776" ]

[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "Vasodilator-stimulated phosphoprotein", "WH1 domain", "VASP tetramerisation domain" ]

4

[ "Evl" ]

[ 114 ]

[ 130 ]

[ "D" ]

6

DP02389

Q96GD4

UPI0000136107

Aurora kinase B

Homo sapiens

9,606

344

0.046512

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-02T10:08:00.167Z

fquaglia

UniRef100_Q96GD4

UniRef90_Q96GD4

UniRef50_Q96GD4

MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQ...

5

[ "DP02389r001", "DP02389r002", "DP02389r003", "DP02389r004", "DP02389r006" ]

[ 221, 230, 230, 221, 221 ]

[ 236, 234, 234, 236, 236 ]

[ 16, 5, 5, 16, 16 ]

[ "disorder", "phosphorylation display site", "phosphorylation display site", "protein binding", "molecular function regulator" ]

[ "IDPO:0000002", "IDPO:0000045", "IDPO:0000045", "GO:0005515", "GO:0098772" ]

[ "Structural state", "Disorder function", "Disorder function", "Molecular function", "Molecular function" ]

[ "ECO:0006220", "ECO:0005670", "ECO:0007731", "ECO:0005670", "ECO:0005670" ]

[ "22920039", "22920039", "14722118", "22920039", "14722118" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:4AF3" ]

[ "pfam" ]

[ "PF00069" ]

[ "Protein kinase domain" ]

1

[ "AIK2", "AIM1", "AIRK2", "ARK2", "AURKB", "STK1", "STK12", "STK5" ]

[ 221 ]

[ 236 ]

[ "D" ]

1

DP02390

Q9NQS7

UPI000006D10F

Inner centromere protein

Homo sapiens

9,606

918

0.022876

[ "Condensates-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-02T10:37:43.374Z

fquaglia

UniRef100_Q9NQS7

UniRef90_Q9NQS7

UniRef50_Q9NQS7

MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQ...

4

[ "DP02390r001", "DP02390r002", "DP02390r003", "DP02390r004" ]

[ 883, 853, 892, 883 ]

[ 903, 903, 896, 903 ]

[ 21, 51, 5, 21 ]

[ "disorder", "protein binding", "phosphorylation display site", "molecular function activator activity" ]

[ "IDPO:0000002", "GO:0005515", "IDPO:0000045", "GO:0140677" ]

[ "Structural state", "Molecular function", "Disorder function", "Molecular function" ]

[ "ECO:0006220", "ECO:0005670", "ECO:0001230", "ECO:0006077" ]

[ "22920039", "22920039", "27332895", "27332895" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Edoardo Salladini" ]

[ "PDB:4AF3" ]

[ "pfam", "pfam" ]

[ "PF03941", "PF12178" ]

[ "Inner centromere protein, ARK binding region", "Chromosome passenger complex (CPC) protein INCENP N terminal" ]

2

[ "INCENP" ]

[ 853, 883 ]

[ 882, 903 ]

[ "F", "D" ]

6

DP02392

Q9ZVD0

UPI00000AC10E

Serrate RNA effector molecule

Arabidopsis thaliana

3,702

720

0.083333

[ "Condensates-related proteins", "RNA-binding proteins" ]

[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "eudicotyledons", "Gunneridae", "Pentapetalae", "rosids", "malvids", "Brassicales", "Brassicaceae", "Camelineae", "Arabidopsis" ]

2021_06

2019-12-02T11:41:01.347Z

fquaglia

UniRef100_Q9ZVD0

UniRef90_Q9ZVD0

UniRef50_Q9ZVD0

MADVNLPPSDSVDNRLPEKSTSSSPPPPPPSSSLPQQEQEQDQQQLPLRRERDSRERRDERDIERPPPNRRERDRSPLPPPRRDYKRRPSLSPPPPYRDRRHSPPQRRSPPQKRYRRDDNGYDGRRGSPRGGYGPPDRRFGYDHGGGYDREMGGRPGYGDERPHGRFMGRYQDWEGGRGGYGDASNSGNPQRDGLMSYKQFIQELEDDILPSEAERRYQEYKSEYITTQKRAFFNTHKEEDWLKNKYHPTNLLSVIERRNDLAQKVAKDFLLDLQSGTLDLGPAVTALNKSGRTSEPNSEDEAAGVGKRKRHGMGGAKEN...

3

[ "DP02392r001", "DP02392r005", "DP02392r006" ]

[ 290, 435, 366 ]

[ 324, 444, 380 ]

[ 35, 10, 15 ]

[ "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "21685453", "21685453", "21685453" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3AX1" ]

[ "pfam", "pfam" ]

[ "PF04959", "PF12066" ]

[ "Arsenite-resistance protein 2", "SERRATE/Ars2, N-terminal domain" ]

2

[ "At2g27100", "SE", "T20P8.15" ]

[ 290, 366, 435 ]

[ 324, 380, 444 ]

[ "D", "D", "D" ]

1

DP02393

Q8IZD2

UPI0000074133

Inactive histone-lysine N-methyltransferase 2E

Homo sapiens

9,606

1,858

0.00915

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_06

2019-12-02T13:46:57.968Z

fquaglia

UniRef100_Q8IZD2

UniRef90_Q8IZD2

UniRef50_Q8IZD2

MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLPYADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRKRENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREAQRIALRLGNGNDKKEMNKSD...

1

[ "DP02393r001" ]

[ 323 ]

[ 339 ]

[ 17 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27812132" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5HT6" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:3.30.40.10", "PF00856", "PF20826" ]

[ "Zinc/RING finger domain, C3HC4 (zinc finger)", "SET domain", "PhD finger domain" ]

3

[ "KMT2E", "MLL5" ]

[ 323 ]

[ 339 ]

[ "D" ]

9

DP02396

Q7RTP6

UPI0001823FDE

[F-actin]-monooxygenase MICAL3

Homo sapiens

9,606

2,002

0.054945

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-02T14:42:37.551Z

fquaglia

UniRef100_Q7RTP6

UniRef90_Q7RTP6

UniRef50_Q7RTP6

MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSLLDKGVILHDYAD...

4

[ "DP02396r001", "DP02396r002", "DP02396r003", "DP02396r004" ]

[ 1881, 1735, 1735, 1735 ]

[ 1990, 1918, 1918, 1918 ]

[ 110, 184, 184, 184 ]

[ "disorder", "protein binding", "localization", "molecular adaptor activity" ]

[ "IDPO:0000002", "GO:0005515", "GO:0051179", "GO:0060090" ]

[ "Structural state", "Molecular function", "Biological process", "Molecular function" ]

[ "ECO:0006220", "ECO:0007731", "ECO:0007731", "ECO:0007731" ]

[ "27552051", "27528609", "27528609", "27528609" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5SZG" ]

[ "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:3.50.50.60", "G3DSA:1.10.418.10", "PF00307", "PF00412", "PF01494", "PF12130", "PF25413" ]

[ "FAD/NAD(P)-binding domain", "Calponin-like domain", "Calponin homology (CH) domain", "LIM domain", "FAD binding domain", "Bivalent Mical/EHBP Rab binding domain", "Mical, Rossman domain" ]

7

[ "KIAA0819", "KIAA1364", "MICAL3" ]

[ 1735, 1881 ]

[ 1880, 1990 ]

[ "F", "D" ]

6

DP02397

P11746

UPI0000168C1C

Pheromone receptor transcription factor

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

286

0.055944

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2021_06

2019-12-02T15:12:08.161Z

fquaglia

UniRef100_P11746

UniRef90_P11746

UniRef50_P11746

MSDIEEGTPTNNGQQKERRKIEIKFIENKTRRHVTFSKRKHGIMKKAFELSVLTGTQVLLLVVSETGLVYTFSTPKFEPIVTQQEGRNLIQACLNAPDDEEEDEEEDGDDDDDDDDDGNDMQRQQPQQQQPQQQQQVLNAHANSLGHLNQDQVPAGALKQEVKSQLLGGANPNQNSMIQQQQHHTQNSQPQQQQQQQPQQQMSQQQMSQHPRPQQGIPHPQQSQPQQQQQQQQQLQQQQQQQQQQPLTGIHQPHQQAFANAASPYLNAEQNAAYQQYFQEPQQGQY

4

[ "DP02397r001", "DP02397r002", "DP02397r003", "DP02397r004" ]

[ 2, 2, 2, 2 ]

[ 17, 17, 17, 17 ]

[ 16, 16, 16, 16 ]

[ "disorder", "phosphorylation display site", "molecular sequestering activity", "phosphorylation display site" ]

[ "IDPO:0000002", "IDPO:0000045", "GO:0140313", "IDPO:0000045" ]

[ "Structural state", "Disorder function", "Molecular function", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "9490409", "9490409", "9490409", "9001236" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:1MNM" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.40.1810.10", "PF00319" ]

[ "Transcription factor, MADS-box", "SRF-type transcription factor (DNA-binding and dimerisation domain)" ]

2

[ "FUN80", "MCM1", "YM9532.08", "YMR043W" ]

[ 2 ]

[ 17 ]

[ "D" ]

2

DP02399

P06730

UPI00001782D7

Eukaryotic translation initiation factor 4E

Homo sapiens

9,606

217

0.16129

[ "NDDs-related proteins", "RNA-binding proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-02T16:17:08.948Z

vacs

UniRef100_P06730

UniRef90_P06730

UniRef50_P06730

MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

3

[ "DP02399r001", "DP02399r003", "DP02399r004" ]

[ 1, 2, 1 ]

[ 29, 35, 26 ]

[ 29, 34, 26 ]

[ "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006165", "ECO:0006220" ]

[ "27773676", "17036047", "11879179" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Veronika Ács", "Veronika Ács" ]

[ "PDB:1IPB", "PDB:1IPC", "PDB:2GPQ", "PDB:5T46" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.30.760.10", "PF01652" ]

[ "RNA Cap, Translation Initiation Factor Eif4e", "Eukaryotic initiation factor 4E" ]

2

[ "EIF4E", "EIF4EL1", "EIF4F" ]

[ 1 ]

[ 35 ]

[ "D" ]

2

DP02400

P48598

UPI0000124818

Eukaryotic translation initiation factor 4E1

Drosophila melanogaster

7,227

259

0.262548

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]

2021_06

2019-12-02T16:26:17.064Z

fquaglia

UniRef100_P48598

UniRef90_P48598

UniRef50_P48598

MQSDFHRMKNFANPKSMFKTSAPSTEQGRPEPPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL

1

[ "DP02400r001" ]

[ 1 ]

[ 68 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27773676" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5T47", "PDB:5T48" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.30.760.10", "PF01652" ]

[ "RNA Cap, Translation Initiation Factor Eif4e", "Eukaryotic initiation factor 4E" ]

2

[ "CG4035", "Eif4e", "eIF-4E", "eIF4E1" ]

[ 1 ]

[ 68 ]

[ "D" ]

1

DP02401

O61380

UPI00000077A8

Eukaryotic translation initiation factor 4G1, isoform A

Drosophila melanogaster

7,227

1,666

0.031212

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]

2023_12

2019-12-02T16:36:35.072Z

fquaglia

UniRef100_O61380

UniRef90_O61380

UniRef50_O61380

MQQAIPTLPTQSDIDKAMQPHSAQNMYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVS...

3

[ "DP02401r003", "DP02401r006", "DP02401r007" ]

[ 633, 578, 638 ]

[ 660, 601, 650 ]

[ 28, 24, 13 ]

[ "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "27773676", "25702871", "25702871" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes" ]

[ "PDB:4UEC", "PDB:5T48" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.25.40.180", "G3DSA:1.25.40.180", "G3DSA:1.25.40.180", "PF02020", "PF02847", "PF02854", "PF21140" ]

[ "G3DSA:1.25.40.180", "G3DSA:1.25.40.180", "G3DSA:1.25.40.180", "eIF4-gamma/eIF5/eIF2-epsilon", "MA3 domain", "MIF4G domain", "Translation initiation factor eIF4G-like, eIF4E-binding domain" ]

7

[ "CG10811", "Dmel\\CG10811", "Dmel_CG10811", "EIF4G", "Eif4G", "deIF4G", "eIF-4G", "eIF4G", "eIF4G-RA", "eIF4G1", "eIF4g", "p200" ]

[ 578, 633 ]

[ 601, 660 ]

[ "D", "D" ]

3

DP02404

Q96N21

UPI0000071221

AP-4 complex accessory subunit Tepsin

Homo sapiens

9,606

525

0.034286

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-02T17:15:00.157Z

fquaglia

UniRef100_Q96N21

UniRef90_Q96N21

UniRef50_Q96N21

MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIASLGSSDLLPQEHILL...

1

[ "DP02404r001" ]

[ 136 ]

[ 153 ]

[ 18 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "28691777" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5WF9" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:1.25.40.90", "PF01417", "PF25827" ]

[ "G3DSA:1.25.40.90", "ENTH domain", "Tepsin VHS/ENTH-like domain" ]

3

[ "C17orf56", "ENTHD2", "TEPSIN" ]

[ 136 ]

[ 153 ]

[ "D" ]

3

DP02405

Q8IYW5

UPI00000741D1

E3 ubiquitin-protein ligase RNF168

Homo sapiens

9,606

571

0.031524

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-03T10:44:05.710Z

fquaglia

UniRef100_Q8IYW5

UniRef90_Q8IYW5

UniRef50_Q8IYW5

MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPWLCACGAEWYHEGNVKTRPSN...

1

[ "DP02405r001" ]

[ 94 ]

[ 111 ]

[ 18 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "23255131" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:4GB0" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.30.40.10", "PF14447" ]

[ "Zinc/RING finger domain, C3HC4 (zinc finger)", "Prokaryotic RING finger family 4" ]

2

[ "RNF168" ]

[ 94 ]

[ 111 ]

[ "D" ]

9

DP02408

Q9P2K3-3

UPI00005AE45B

Isoform 3 of REST corepressor 3

Homo sapiens

9,606

553

0.759494

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_06

2019-12-03T11:29:29.206Z

fquaglia

MPGMMEKGPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDVGMRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQV...

2

[ "DP02408r001", "DP02408r002" ]

[ 1, 406 ]

[ 272, 553 ]

[ 272, 148 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "24820421", "24820421" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:4CZZ" ]

[]

0

[ "KIAA1343", "RCOR3" ]

[ 1, 406 ]

[ 272, 553 ]

[ "D", "D" ]

3

DP02410

P21952

UPI000002961F

POU domain, class 3, transcription factor 1

Mus musculus

10,090

449

0.053452

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2021_06

2019-12-03T14:18:13.467Z

fquaglia

UniRef100_P21952

UniRef90_P20267

UniRef50_P20267

MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGGTAHHLGPAMSPSPGAGGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDS...

2

[ "DP02410r001", "DP02410r002" ]

[ 319, 319 ]

[ 342, 342 ]

[ 24, 24 ]

[ "flexible linker", "disorder" ]

[ "IDPO:0000033", "IDPO:0000002" ]

[ "Disorder function", "Structural state" ]

[ "ECO:0006165", "ECO:0006165" ]

[ "21117060", "21117060" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:2XSD" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:1.10.260.40", "PF00046", "PF00157" ]

[ "lambda repressor-like DNA-binding domains", "Homeodomain", "Pou domain - N-terminal to homeobox domain" ]

3

[ "Oct6", "Otf-6", "Otf6", "Pou3f1", "Scip" ]

[ 319 ]

[ 342 ]

[ "D" ]

2

DP02411

Q08050

UPI000016AD75

Forkhead box protein M1

Homo sapiens

9,606

763

0.279161

[ "Condensates-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-03T14:37:04.644Z

smribeiro

UniRef100_Q08050

UniRef90_Q08050

UniRef50_Q08050

MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNSLSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTL...

7

[ "DP02411r001", "DP02411r002", "DP02411r005", "DP02411r006", "DP02411r007", "DP02411r008", "DP02411r009" ]

[ 222, 327, 1, 694, 694, 1, 1 ]

[ 231, 360, 114, 748, 748, 114, 114 ]

[ 10, 34, 114, 55, 55, 114, 114 ]

[ "disorder", "disorder", "disorder", "disorder", "protein binding", "disorder", "protein binding" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0005515", "IDPO:0000002", "GO:0005515" ]

[ "Structural state", "Structural state", "Structural state", "Structural state", "Molecular function", "Structural state", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006204", "ECO:0006204", "ECO:0005647", "ECO:0007680", "ECO:0005647" ]

[ "20360045", "20360045", "31134895", "31134895", "31134895", "31134895", "31134895" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Sandra Macedo-Ribeiro", "Sandra Macedo-Ribeiro", "Sandra Macedo-Ribeiro", "Sandra Macedo-Ribeiro", "Sandra Macedo-Ribeiro" ]

[ "PDB:3G73" ]

[ "gene3D", "pfam" ]

[ "G3DSA:1.10.10.10", "PF00250" ]

[ "Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain", "Forkhead domain" ]

2

[ "FKHL16", "FOXM1", "HFH11", "MPP2", "WIN" ]

[ 1, 222, 327, 694 ]

[ 114, 231, 360, 748 ]

[ "D", "D", "D", "D" ]

2

DP02412

O88513

UPI0000020FC1

Geminin

Mus musculus

10,090

206

0.053398

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2020_12

2019-12-03T15:01:07.832Z

fquaglia

UniRef100_O88513

UniRef90_O88513

UniRef50_O75496

MNLSMKQKQEGAQENVKNSPVPRRTLKMIQPSADGSLVGRENELPKGLFKRKLWDDQLASQTSSCGPEANENKDVGDLTQEAFDLISKENPSSQYWKEVAEQRRKALYEALKENEKLHKEIEQKDSEIARLRKENKDLAEVAEHVQYMAEVIERLSNEPLDNFESPDSQEFDSEEEAVEYSELEDSGAGTCAEETVSSSTDARPCT

4

[ "DP02412r001", "DP02412r002", "DP02412r003", "DP02412r005" ]

[ 79, 79, 79, 79 ]

[ 89, 89, 89, 89 ]

[ 11, 11, 11, 11 ]

[ "disorder", "disorder to order", "protein binding", "protein binding" ]

[ "IDPO:0000002", "IDPO:0000011", "GO:0005515", "GO:0005515" ]

[ "Structural state", "Structural transition", "Molecular function", "Molecular function" ]

[ "ECO:0006220", "ECO:0005670", "ECO:0005670", "ECO:0005647" ]

[ "15286659", "15286659", "15286659", "15286659" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:2ZXX" ]

[ "pfam" ]

[ "PF07412" ]

[ "Geminin" ]

1

[ "Gmnn" ]

[ 79 ]

[ 89 ]

[ "T" ]

7

DP02413

P04198

UPI00001732CE

N-myc proto-oncogene protein

Homo sapiens

9,606

464

0.071121

[ "Cancer-related proteins", "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2022_06

2019-12-03T16:48:39.750Z

fquaglia

UniRef100_P04198

UniRef90_P04198

UniRef50_P04198

MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELIL...

1

[ "DP02413r001" ]

[ 28 ]

[ 60 ]

[ 33 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27837025" ]

[ "pmid" ]

[ "Victoria Nugnes" ]

[ "PDB:5G1X" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:4.10.280.10", "PF00010", "PF01056" ]

[ "Helix-loop-helix DNA-binding domain", "Helix-loop-helix DNA-binding domain", "Myc amino-terminal region" ]

3

[ "BHLHE37", "MYCN", "NMYC" ]

[ 28 ]

[ 60 ]

[ "D" ]

9

DP02414

P14653

UPI000012CF4A

Homeobox protein Hox-B1

Homo sapiens

9,606

301

0.066445

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-04T10:02:53.466Z

fquaglia

UniRef100_P14653

UniRef90_P14653

UniRef50_P14653

MDYNRMNSFLEYPLCNRGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREEGRVPPAPPGCPKEAAGDASDQSTCTSPEASPSSVTS

2

[ "DP02414r001", "DP02414r002" ]

[ 187, 187 ]

[ 206, 206 ]

[ 20, 20 ]

[ "disorder", "flexible linker" ]

[ "IDPO:0000002", "IDPO:0000033" ]

[ "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "10052460", "10052460" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:1B72" ]

[ "pfam" ]

[ "PF00046" ]

[ "Homeodomain" ]

1

[ "HOX2I", "HOXB1" ]

[ 187 ]

[ 206 ]

[ "D" ]

7

DP02415

P54274

UPI0000001C9C

Telomeric repeat-binding factor 1

Homo sapiens

9,606

439

0.09795

[ "Condensates-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-04T11:11:38.930Z

fquaglia

UniRef100_P54274

UniRef90_P54274

UniRef50_P54274

MAEDVSSAAPSPRGCADGRDADPTEEQMAETERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDKQSAVTESSEGTVSLLRSHKN...

2

[ "DP02415r005", "DP02415r006" ]

[ 1, 23 ]

[ 10, 55 ]

[ 10, 33 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "27050267", "27050267" ]

[ "pmid", "pmid" ]

[ "Victoria Nugnes", "Victoria Nugnes" ]

[ "PDB:5HKP" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:1.25.40.210", "PF00249", "PF08558" ]

[ "Telomere repeat-binding factor, dimerisation domain", "Myb-like DNA-binding domain", "Telomere repeat binding factor (TRF)" ]

3

[ "PIN2", "TERF1", "TRBF1", "TRF", "TRF1" ]

[ 1, 23 ]

[ 10, 55 ]

[ "D", "D" ]

4

DP02417

P49765

UPI000002B6B4

Vascular endothelial growth factor B

Homo sapiens

9,606

207

0.333333

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-04T13:48:07.740Z

fquaglia

UniRef100_P49765

UniRef90_P49765

UniRef50_P49765

MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA

4

[ "DP02417r001", "DP02417r002", "DP02417r003", "DP02417r004" ]

[ 37, 37, 37, 130 ]

[ 46, 46, 46, 188 ]

[ 10, 10, 10, 59 ]

[ "disorder", "disorder to order", "protein binding", "disorder" ]

[ "IDPO:0000002", "IDPO:0000011", "GO:0005515", "IDPO:0000002" ]

[ "Structural state", "Structural transition", "Molecular function", "Structural state" ]

[ "ECO:0006220", "ECO:0005670", "ECO:0005670", "ECO:0006220" ]

[ "18930733", "18930733", "18930733", "18930733" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:2VWE" ]

[ "gene3D", "pfam" ]

[ "G3DSA:2.10.90.10", "PF00341" ]

[ "Cystine-knot cytokines", "PDGF/VEGF domain" ]

2

[ "VEGFB", "VRF" ]

[ 37, 130 ]

[ 46, 188 ]

[ "T", "D" ]

1

DP02418

P35568

UPI000003BB52

Insulin receptor substrate 1

Homo sapiens

9,606

1,242

0.034622

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-04T14:50:04.407Z

fquaglia

UniRef100_P35568

UniRef90_P35568

UniRef50_P35568

MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGK...

2

[ "DP02418r001", "DP02418r002" ]

[ 117, 117 ]

[ 159, 159 ]

[ 43, 43 ]

[ "disorder", "flexible linker" ]

[ "IDPO:0000002", "IDPO:0000033" ]

[ "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "10411883", "10411883" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:1QQG" ]

[ "gene3D", "gene3D", "pfam", "pfam" ]

[ "G3DSA:2.30.29.30", "G3DSA:2.30.29.30", "PF00169", "PF02174" ]

[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "PH domain", "PTB domain (IRS-1 type)" ]

4

[ "IRS1" ]

[ 117 ]

[ 159 ]

[ "D" ]

5

DP02419

Q5SQI0

UPI000014137B

Alpha-tubulin N-acetyltransferase 1

Homo sapiens

9,606

421

0.123515

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-04T15:45:11.063Z

fquaglia

UniRef100_Q5SQI0

UniRef90_Q5SQI0

UniRef50_Q5SQI0

MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRR...

3

[ "DP02419r001", "DP02419r002", "DP02419r003" ]

[ 26, 196, 231 ]

[ 36, 236, 235 ]

[ 11, 41, 5 ]

[ "disorder", "disorder", "acetylation display site" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000039" ]

[ "Structural state", "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0005801" ]

[ "23071314", "23071314", "23071314" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:4GS4" ]

[ "pfam" ]

[ "PF05301" ]

[ "GNAT acetyltransferase, Mec-17" ]

1

[ "ATAT1", "C6orf134", "MEC17", "Nbla00487" ]

[ 26, 196 ]

[ 36, 236 ]

[ "D", "D" ]

2

DP02420

Q86YV5

UPI0003EAF98F

Inactive tyrosine-protein kinase PRAG1

Homo sapiens

9,606

1,406

0.049787

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-04T16:12:29.334Z

fquaglia

UniRef100_Q86YV5

UniRef90_Q86YV5

UniRef50_D3ZMK9

MHQTLCLNPESLKMSACSDFVEHIWKPGSCKNCFCLRSDHQLVAGPPQPRAGSLPPPPRLPPRPENCRLEDEGVNSSPYSKPTIAVKPTMMSSEASDVWTEANLSAEVSQVIWRRAPGKLPLPKQEDAPVVYLGSFRGVQKPAGPSTSPDGNSRCPPAYTMVGLHNLEPRGERNIAFHPVSFPEEKAVHKEKPSFPYQDRPSTQESFRQKLAAFAGTTSGCHQGPGPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCCPGSPVAKAASQTAGSRGRHGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGPTAHP...

5

[ "DP02420r001", "DP02420r002", "DP02420r003", "DP02420r004", "DP02420r005" ]

[ 932, 1030, 1065, 1218, 1336 ]

[ 943, 1039, 1081, 1238, 1345 ]

[ 12, 10, 17, 21, 10 ]

[ "disorder", "disorder", "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "29079850", "29079850", "29079850", "29079850", "29079850" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5VE6" ]

[ "pfam" ]

[ "PF07714" ]

[ "Protein tyrosine and serine/threonine kinase" ]

1

[ "PRAG1", "SGK223" ]

[ 932, 1030, 1065, 1218, 1336 ]

[ 943, 1039, 1081, 1238, 1345 ]

[ "D", "D", "D", "D", "D" ]

4

DP02421

O94687

UPI000006B698

RNA-induced transcriptional silencing complex protein tas3

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

284,812

549

0.612022

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Taphrinomycotina", "Schizosaccharomycetes", "Schizosaccharomycetales", "Schizosaccharomycetaceae", "Schizosaccharomyces" ]

2023_12

2019-12-04T16:29:33.096Z

fquaglia

UniRef100_O94687

UniRef90_O94687

UniRef50_O94687

MEKGIKKYLPSLPFLACISDFPENHGTSRRSATVSLERVHELFTEHWLSNLKNRREKRQELAEEAVYCRSEMLSQRKLLAAVDFPQQLKNSPAKAKATHTSSGVTKEVRASKKYTSSNVEFPLVTDGKEKPVKSKQLRKNSVTEFEKPIETKKSKHRKSRNKFLDKSSGSMEIESWDNSTSDSIIESSSRLHESISLRENDIRSSDSKSVGWDDNSTGFRESSKSLDHTDTSMFMELDSNSDPQFRPKYQAKSSWFAPDDPEASWGNLDDGWGETNGSWSSTDDTKHYKNEWAESINLDNFNRPSQQEDYDKPKNTQVSR...

2

[ "DP02421r001", "DP02421r002" ]

[ 426, 117 ]

[ 436, 452 ]

[ 11, 336 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006216" ]

[ "19394293", "28608349" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Victoria Nugnes" ]

[ "PDB:3D1B", "PDB:3D1D" ]

[ "pfam", "pfam" ]

[ "PF21487", "PF22378" ]

[ "Tas3, C-terminal helical domains", "Tas3-like, N-terminal domain" ]

2

[ "SPBC83.03c", "tas3" ]

[ 117 ]

[ 452 ]

[ "D" ]

6

DP02422

O35254

UPI00000E6C57

Golgi reassembly-stacking protein 1

Rattus norvegicus

10,116

451

0.02439

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]

2021_06

2019-12-04T16:51:23.294Z

fquaglia

UniRef100_O35254

UniRef90_O35254

UniRef50_Q9BQQ3

MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLRPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQYKKPPSASSPGTPAKTPQPNAFPLGAPPPWPIPQDSSGPELGSRQSDYMEALPQVPGGFMEEQLPGPGSPGHGTADYGGCLHSMEIPLQPPPPVQRVMDPGFLDVSGMSLLD...

1

[ "DP02422r001" ]

[ 1 ]

[ 11 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "23940043" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:4KFV" ]

[ "gene3D", "pfam" ]

[ "G3DSA:2.30.42.10", "PF04495" ]

[ "G3DSA:2.30.42.10", "GRASP55/65 PDZ-like domain" ]

2

[ "Gorasp1", "Grasp65" ]

[ 1 ]

[ 11 ]

[ "D" ]

1

DP02423

Q5RJI5

UPI0000470E43

Serine/threonine-protein kinase BRSK1

Mus musculus

10,090

778

0.015424

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2021_06

2019-12-04T17:13:30.929Z

fquaglia

UniRef100_Q5RJI5

UniRef90_Q5RJI5

UniRef50_Q5RJI5

MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVL...

3

[ "DP02423r001", "DP02423r002", "DP02423r003" ]

[ 592, 592, 592 ]

[ 603, 603, 603 ]

[ 12, 12, 12 ]

[ "disorder", "self-inhibition", "molecular function inhibitor activity" ]

[ "IDPO:0000002", "IDPO:0000059", "GO:0140678" ]

[ "Structural state", "Disorder function", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "27251228", "27251228", "27251228" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5IRI" ]

[ "pfam", "pfam", "pfam" ]

[ "PF00069", "PF21115", "PF21122" ]

[ "Protein kinase domain", "BRSK1/2 UBA domain", "BRSK1/2 KA1 domain" ]

3

[ "Brsk1", "Gm1100", "Sadb" ]

[ 592 ]

[ 603 ]

[ "D" ]

1

DP02427

Q9BVI0

UPI000006E61B

PHD finger protein 20

Homo sapiens

9,606

1,012

0.01581

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-05T14:24:36.802Z

fquaglia

UniRef100_Q9BVI0

UniRef90_Q9BVI0

UniRef50_Q9BVI0

MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRGRPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTD...

1

[ "DP02427r001" ]

[ 70 ]

[ 85 ]

[ 16 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "22449972" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3Q1J", "PDB:3QII" ]

[ "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:3.30.40.10", "PF12618", "PF18115", "PF20826" ]

[ "Zinc/RING finger domain, C3HC4 (zinc finger)", "PHD finger protein 20, AT-hook", "DNA repair protein Crb2 Tudor domain", "PhD finger domain" ]

4

[ "C20orf104", "GLEA2", "HCA58", "NZF", "PHF20", "TZP" ]

[ 70 ]

[ 85 ]

[ "D" ]

6

DP02428

Q5T4W7

UPI000013C9E4

Artemin

Homo sapiens

9,606

220

0.059091

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-05T14:35:51.240Z

fquaglia

UniRef100_Q5T4W7

UniRef90_Q5T4W7

UniRef50_Q5T4W7

MELGLGGLSTLSHCPWPRQQPALWPTLAALALLSSVAEASLGSAPRSPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG

1

[ "DP02428r001" ]

[ 108 ]

[ 120 ]

[ 13 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "16734417" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:2ASK" ]

[ "gene3D", "pfam" ]

[ "G3DSA:2.10.90.10", "PF00019" ]

[ "Cystine-knot cytokines", "Transforming growth factor beta like domain" ]

2

[ "ARTN", "EVN" ]

[ 108 ]

[ 120 ]

[ "D" ]

3

DP02429

Q9WTY2

UPI00000E7B02

GTP-binding protein REM 2

Rattus norvegicus

10,116

341

0.076246

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]

2020_12

2019-12-05T16:15:24.133Z

fquaglia

UniRef100_Q9WTY2

UniRef90_Q9WTY2

UniRef50_Q9WTY2

MHTDLDTDMDADTETVALCSSSSRQASPSGTPTPEADTTLLKQKPEKLLAELDRGGPPPAPGVPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAALAQKDGVFKVMLLGESGVGKSTLAGTFGGLQGDNAHEMENSEDTYERRIMVDKEEVTLIVYDIWEQGDAGGWLQDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRGHAGGQRPEPSSPDGPAPPTRRESLTKKAKRFLANL...

2

[ "DP02429r001", "DP02429r002" ]

[ 137, 171 ]

[ 150, 182 ]

[ 14, 12 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "22684057", "22684057" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:4AII" ]

[ "pfam" ]

[ "PF00071" ]

[ "Ras family" ]

1

[ "Rem2" ]

[ 137, 171 ]

[ 150, 182 ]

[ "D", "D" ]

4

DP02431

P15391

UPI000016A560

B-lymphocyte antigen CD19

Homo sapiens

9,606

556

0.026978

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-06T09:36:06.634Z

fquaglia

UniRef100_P15391

UniRef90_P15391

UniRef50_P15391

MPPPRLLFFLLFLTPMEVRPEEPLVVKVEEGDNAVLQCLKGTSDGPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPPSEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWAKDRPEIWEGEPPCLPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVHPKGPKSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITARPVLWHWLLRTGGWKVSAVTLAYLIFCLCSLVGILHLQRALVLR...

1

[ "DP02431r001" ]

[ 138 ]

[ 152 ]

[ 15 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "29490423" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:6AL5" ]

[ "gene3D" ]

[ "G3DSA:2.60.40.10" ]

[ "Immunoglobulins" ]

1

[ "CD19" ]

[ 138 ]

[ 152 ]

[ "D" ]

4

DP02445

Q96RS0

UPI000006DC33

Trimethylguanosine synthase

Homo sapiens

9,606

853

0.018757

[ "RNA-binding proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-06T13:01:23.831Z

fquaglia

UniRef100_Q96RS0

UniRef90_Q96RS0

UniRef50_Q96RS0

MCCEKWSRVAEMFLFIEEREDCKILCLCSRAFVEDRKLYNLGLKGYYIRDSGNNSGDQATEEEEGGYSCGTAESHDSKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENTRTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWEAQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDG...

1

[ "DP02445r001" ]

[ 618 ]

[ 633 ]

[ 16 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "19386620" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3GDH" ]

[ "pfam" ]

[ "PF09445" ]

[ "RNA cap guanine-N2 methyltransferase" ]

1

[ "HCA137", "NCOA6IP", "PIMT", "TGS1" ]

[ 618 ]

[ 633 ]

[ "D" ]

4

DP02446

Q8IU57

UPI000004D3FC

Interferon lambda receptor 1

Homo sapiens

9,606

520

0.057692

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-06T13:56:20.291Z

fquaglia

UniRef100_Q8IU57

UniRef90_Q8IU57

UniRef50_Q8IU57

MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTRGVRPTPRVRAPATQQTRWKK...

1

[ "DP02446r001" ]

[ 270 ]

[ 299 ]

[ 30 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27133025" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5IXD", "PDB:5IXI" ]

[ "gene3D", "gene3D", "pfam" ]

[ "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "PF01108" ]

[ "Immunoglobulins", "Immunoglobulins", "Tissue factor" ]

3

[ "IFNLR1", "IL28RA", "LICR2" ]

[ 270 ]

[ 299 ]

[ "D" ]

8

DP02448

Q03707

UPI0000168A8A

Inner nuclear membrane protein SRC1

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

834

0.310552

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2023_12

2019-12-09T09:15:19.962Z

fquaglia

UniRef100_Q03707

UniRef90_Q03707

UniRef50_Q03707

MNSDLEYLEDGFDPNSMKVATLRRILVENNVDFPSNARKNALVGLFDEKVKPQIPQLRKMYLNVRPSDEGIVKMDRPSSSPSIASPRRSRRARREKSASPMAKQFKKNRILDDVSNDDDDDDDDDDDNDKKDDPLIVPSGTDTDEVDDEEDDVITSSSNKSDTNDFQQNSDTRKKRKDPDSDDWSESNSKENKIDNKHLNLLSSDSEIEQDYQKAKKRKTSDLNQEHGNGSAILGKLSVKTPIKNTNRKPVSMDNFNDSLTSSGTENDPFVPNIRHNPKELGTANGTGHSTPLSKLKVSASFADKLPQKEVPSTILVPEV...

4

[ "DP02448r001", "DP02448r005", "DP02448r006", "DP02448r007" ]

[ 196, 222, 222, 222 ]

[ 221, 454, 454, 454 ]

[ 26, 233, 233, 233 ]

[ "disorder", "disorder", "disorder", "flexible linker" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000033" ]

[ "Structural state", "Structural state", "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0000302", "ECO:0000302", "ECO:0000302" ]

[ "26051712", "23357007", "26051712", "26051712" ]

[ "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]

[ "PDB:4XZR" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:1.10.10.1180", "PF09402", "PF12949" ]

[ "G3DSA:1.10.10.1180", "Man1-Src1p-C-terminal domain", "HeH/LEM domain" ]

3

[ "HEH1", "SRC1", "YML033W", "YML034W" ]

[ 196 ]

[ 454 ]

[ "D" ]

7

DP02449

Q15583

UPI0000140386

Homeobox protein TGIF1

Homo sapiens

9,606

401

0.309227

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_06

2019-12-09T11:18:41.798Z

fquaglia

UniRef100_Q15583

UniRef90_Q15583

UniRef50_Q15583

MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYLPPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQS...

7

[ "DP02449r001", "DP02449r002", "DP02449r003", "DP02449r005", "DP02449r007", "DP02449r008", "DP02449r009" ]

[ 150, 235, 256, 256, 284, 289, 292 ]

[ 167, 248, 347, 347, 288, 293, 296 ]

[ 18, 14, 92, 92, 5, 5, 5 ]

[ "disorder", "disorder", "disorder", "protein binding", "phosphorylation display site", "phosphorylation display site", "phosphorylation display site" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0005515", "IDPO:0000045", "IDPO:0000045", "IDPO:0000045" ]

[ "Structural state", "Structural state", "Structural state", "Molecular function", "Disorder function", "Disorder function", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006165", "ECO:0006165", "ECO:0006165", "ECO:0006165", "ECO:0006165" ]

[ "30060237", "30060237", "30060237", "30060237", "30060237", "30060237", "30060237" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "BMRB:27461", "PDB:6FQP" ]

[ "pfam" ]

[ "PF05920" ]

[ "Homeobox KN domain" ]

1

[ "TGIF", "TGIF1" ]

[ 150, 235, 256 ]

[ 167, 248, 347 ]

[ "D", "D", "D" ]

2

DP02451

P46938

UPI00000E5DEC

Transcriptional coactivator YAP1

Mus musculus

10,090

488

0.061475

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2020_12

2019-12-09T12:51:12.922Z

fquaglia

UniRef100_P46938

UniRef90_P46938

UniRef50_P46937-6

MEPAQQPPPQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTASGVVSGPAAAPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPAPASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQELFRQAIRNINP...

1

[ "DP02451r001" ]

[ 35 ]

[ 64 ]

[ 30 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "20123908" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3JUA" ]

[ "pfam", "pfam", "pfam" ]

[ "PF00397", "PF00397", "PF15238" ]

[ "WW domain", "WW domain", "Omega loop, TEAD interacting region 3" ]

3

[ "Yap", "Yap1", "Yap65" ]

[ 35 ]

[ 64 ]

[ "D" ]

1

DP02452

Q8TEA8

UPI0000072859

D-aminoacyl-tRNA deacylase 1

Homo sapiens

9,606

209

0.277512

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-09T13:24:03.429Z

fquaglia

UniRef100_Q8TEA8

UniRef90_Q8TEA8

UniRef50_Q8TEA8

MKAVVQRVTRASVTVGGEQISAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKQYEILCVSQFTLQCVLKGNKPDFHLAMPTEQAEGFYNSFLEQLRKTYRPELIKDGKFGAYMQVHIQNDGPVTIELESPAPGTATSDPKQLSKLEKQQQRKEKTRAKGPSESSKERNTPRKEDRSASSGAEGDVSSEREP

3

[ "DP02452r001", "DP02452r002", "DP02452r003" ]

[ 152, 152, 152 ]

[ 209, 209, 209 ]

[ 58, 58, 58 ]

[ "disorder", "DNA binding", "disorder to order" ]

[ "IDPO:0000002", "GO:0003677", "IDPO:0000011" ]

[ "Structural state", "Molecular function", "Structural transition" ]

[ "ECO:0006220", "ECO:0005670", "ECO:0005670" ]

[ "17264083", "17264083", "17264083" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:2OKV" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.50.80.10", "PF02580" ]

[ "G3DSA:3.50.80.10", "D-Tyr-tRNA(Tyr) deacylase" ]

2

[ "C20orf88", "DTD1", "DUEB", "HARS2" ]

[ 152 ]

[ 209 ]

[ "T" ]

8

DP02455

Q9UKX7

UPI00001698D2

Nuclear pore complex protein Nup50

Homo sapiens

9,606

468

0.132479

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2020_12

2019-12-09T14:13:37.246Z

fquaglia

UniRef100_Q9UKX7

UniRef90_Q9UKX7

UniRef50_Q9UKX7

MAKRNAEKELTDRNWDQEDEAEEVGTFSMASEEVLKNRAIKKAKRRNVGFESDTGGAFKGFKGLVVPSGGGRFSGFGSGAGGKPLEGLSNGNNITSAPPFASAKAAADPKVAFGSLAANGPTTLVDKVSNPKTNGDSQQPSSSGLASSKACVGNAYHKQLAALNCSVRDWIVKHVNTNPLCDLTPIFKDYEKYLANIEQQHGNSGRNSESESNKVAAETQSPSLFGSTKLQQESTFLFHGNKTEDTPDKKMEVASEKKTDPSSLGATSASFNFGKKVDSSVLGSLSSVPLTGFSFSPGNSSLFGKDTTQSKPVSSPFPTK...

1

[ "DP02455r001" ]

[ 48 ]

[ 109 ]

[ 62 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "22130666" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3TJ3" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:2.30.29.30", "PF00638", "PF08911" ]

[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "RanBP1 domain", "NUP50 (Nucleoporin 50 kDa)" ]

3

[ "NPAP60L", "NUP50", "PRO1146" ]

[ 48 ]

[ 109 ]

[ "D" ]

8

DP02456

O35625

UPI0000151A74

Axin-1

Mus musculus

10,090

863

0.053302

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2020_12

2019-12-09T15:40:02.276Z

fquaglia

UniRef100_O35625

UniRef90_O35625

UniRef50_O35625

MNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSAND...

3

[ "DP02456r001", "DP02456r002", "DP02456r003" ]

[ 1, 31, 19 ]

[ 17, 59, 30 ]

[ 17, 29, 12 ]

[ "disorder", "disorder", "protein binding" ]

[ "IDPO:0000002", "IDPO:0000002", "GO:0005515" ]

[ "Structural state", "Structural state", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0005647" ]

[ "22307604", "22307604", "22307604" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3UTM" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.10.196.10", "G3DSA:1.10.196.10", "G3DSA:3.10.20.380", "PF00615", "PF00778", "PF08833", "PF16646" ]

[ "G3DSA:1.10.196.10", "G3DSA:1.10.196.10", "G3DSA:3.10.20.380", "Regulator of G protein signaling domain", "DIX domain", "Axin beta-catenin binding motif", "Axin-1 tankyrase binding domain" ]

7

[ "Axin", "Axin1", "Fu" ]

[ 1, 19, 31 ]

[ 17, 30, 59 ]

[ "D", "F", "D" ]

4

DP02457

O95400

UPI000006D625

CD2 antigen cytoplasmic tail-binding protein 2

Homo sapiens

9,606

341

0.073314

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-09T16:40:38.550Z

fquaglia

UniRef100_O95400

UniRef90_O95400

UniRef50_O95400

MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRERPPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGRKGPGQPSSPQRLDRLSGLADQMVARGNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCR...

1

[ "DP02457r001" ]

[ 256 ]

[ 280 ]

[ 25 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "17467737" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1SYX" ]

[ "gene3D", "pfam" ]

[ "G3DSA:3.30.1490.40", "PF02213" ]

[ "G3DSA:3.30.1490.40", "GYF domain" ]

2

[ "CD2BP2", "KIAA1178" ]

[ 256 ]

[ 280 ]

[ "D" ]

6

DP02458

P17181

UPI000002D51B

Interferon alpha/beta receptor 1

Homo sapiens

9,606

557

0.210054

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-10T10:44:04.872Z

fquaglia

UniRef100_P17181

UniRef90_P17181

UniRef50_P17181

MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSE...

2

[ "DP02458r001", "DP02458r002" ]

[ 49, 330 ]

[ 58, 436 ]

[ 10, 107 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "21854986", "21854986" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3S98", "PDB:3SE3", "PDB:3SE4" ]

[ "gene3D", "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "PF01108", "PF09294", "PF09294" ]

[ "Immunoglobulins", "Immunoglobulins", "Immunoglobulins", "Immunoglobulins", "Tissue factor", "Interferon-alpha/beta receptor, fibronectin type III", "Interferon-alpha/beta receptor, fibronectin type III" ]

7

[ "IFNAR", "IFNAR1" ]

[ 49, 330 ]

[ 58, 436 ]

[ "D", "D" ]

6

DP02460

Q23985

UPI000007A4B8

Protein deltex

Drosophila melanogaster

7,227

738

0.092141

[]

[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]

2020_12

2019-12-10T11:19:38.212Z

fquaglia

UniRef100_Q23985

UniRef90_Q23985

UniRef50_Q23985

MASSAGSAASGSVVPGGGGSAASSCATMALSTAGSGGPPVNHAHAVCVWEFESRGKWLPYSPAVSQHLERAHAKKLTRVMLSDADPSLEQYYVNVRTMTQESEAETAGSGLLTIGVRRMFYAPSSPAGKGTKWEWSGGSADSNNDWRPYNMHVQCIIEDAWARGEQTLDLCNTHIGLPYTINFCNLTQLRQPSGPMRSIRRTQQAPYPLVKLTPQQANQLKSNSASVSSQYNTLPKLGDTKSLHRVPMTRQQHPLPTSHQVQQQQHQHQHQQQQQQQHHHQHQQQQHQQQQQHQMQHHQIHHQTAPRKPPKKHSEISTTN...

2

[ "DP02460r001", "DP02460r002" ]

[ 26, 212 ]

[ 43, 261 ]

[ 18, 50 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "16271883", "16271883" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:2A90" ]

[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:3.30.40.10", "G3DSA:3.30.720.50", "G3DSA:3.30.390.130", "PF02825", "PF02825", "PF18102" ]

[ "Zinc/RING finger domain, C3HC4 (zinc finger)", "G3DSA:3.30.720.50", "G3DSA:3.30.390.130", "WWE domain", "WWE domain", "Deltex C-terminal domain" ]

6

[ "CG3929", "dx" ]

[ 26, 212 ]

[ 43, 261 ]

[ "D", "D" ]

2

DP02461

P17105

UPI00001679B7

Inositol-trisphosphate 3-kinase A

Rattus norvegicus

10,116

459

0.039216

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]

2021_06

2019-12-10T11:31:33.159Z

fquaglia

UniRef100_P17105

UniRef90_P17105

UniRef50_P17105

MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGI...

1

[ "DP02461r001" ]

[ 185 ]

[ 202 ]

[ 18 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "15350215" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1TZD" ]

[ "gene3D", "pfam" ]

[ "G3DSA:1.10.510.50", "PF03770" ]

[ "G3DSA:1.10.510.50", "Inositol polyphosphate kinase" ]

2

[ "Itpka" ]

[ 185 ]

[ 202 ]

[ "D" ]

3

DP02463

Q9NRR4

UPI0000163BD8

Ribonuclease 3

Homo sapiens

9,606

1,374

0.206696

[ "Cancer-related proteins", "RNA-binding proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-10T14:29:20.947Z

fquaglia

UniRef100_Q9NRR4

UniRef90_Q9NRR4

UniRef50_Q9NRR4

MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGL...

5

[ "DP02463r001", "DP02463r002", "DP02463r003", "DP02463r004", "DP02463r005" ]

[ 390, 459, 712, 930, 1333 ]

[ 411, 521, 849, 957, 1365 ]

[ 22, 63, 138, 28, 33 ]

[ "disorder", "disorder", "disorder", "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state", "Structural state", "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "26748718", "26748718", "26748718", "26748718", "26748718" ]

[ "pmid", "pmid", "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5B16" ]

[ "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.10.1520.10", "G3DSA:1.10.1520.10", "PF00035", "PF00636", "PF14622", "PF26050" ]

[ "Ribonuclease III domain", "Ribonuclease III domain", "Double-stranded RNA binding motif", "Ribonuclease III domain", "Ribonuclease-III-like", "Ribonuclease 3, central domain, two antiparallel helical region" ]

6

[ "DROSHA", "RN3", "RNASE3L", "RNASEN" ]

[ 390, 459, 712, 930, 1333 ]

[ 411, 521, 849, 957, 1365 ]

[ "D", "D", "D", "D", "D" ]

7

DP02464

Q12476

UPI00000530F6

Protein AIR2

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

344

0.037791

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2020_12

2019-12-10T15:03:09.956Z

fquaglia

UniRef100_Q12476

UniRef90_Q12476

UniRef50_Q12476

MEKNTAPFVVDTAPTTPPDKLVAPSIEEVNSNPNELRALRGQGRYFGVSDDDKDAIKEAAPKCNNCSQRGHLKKDCPHIICSYCGATDDHYSRHCPKAIQCSKCDEVGHYRSQCPHKWKKVQCTLCKSKKHSKERCPSIWRAYILVDDNEKAKPKVLPFHTIYCYNCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENEDYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGETLSLNNNISKNSRYQNTKVNVSSISENMYGSRYNPSTYVDNNSI...

3

[ "DP02464r001", "DP02464r002", "DP02464r003" ]

[ 147, 147, 147 ]

[ 159, 159, 159 ]

[ 13, 13, 13 ]

[ "disorder", "flexible linker", "molecular adaptor activity" ]

[ "IDPO:0000002", "IDPO:0000033", "GO:0060090" ]

[ "Structural state", "Disorder function", "Molecular function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]

[ "20696927", "20696927", "20696927" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:3NYB" ]

[ "pfam", "pfam", "pfam", "pfam" ]

[ "PF00098", "PF00098", "PF00098", "PF21759" ]

[ "Zinc knuckle", "Zinc knuckle", "Zinc knuckle", "AIR2-like, CCHC-type 1 zinc finger 4" ]

4

[ "AIR2", "YDL175C" ]

[ 147 ]

[ 159 ]

[ "D" ]

6

DP02465

P07199

UPI000016A6A2

Major centromere autoantigen B

Homo sapiens

9,606

599

0.028381

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_12

2019-12-10T15:16:03.696Z

fquaglia

UniRef100_P07199

UniRef90_P07199

UniRef50_P07199

MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPG...

1

[ "DP02465r001" ]

[ 583 ]

[ 599 ]

[ 17 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "14522975" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:1UFI" ]

[ "gene3D", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.10.287.1090", "PF03184", "PF03221", "PF04218", "PF09026" ]

[ "Dimerisation domain of CENP-B", "DDE superfamily endonuclease", "Tc5 transposase DNA-binding domain", "CENP-B N-terminal DNA-binding domain", "Centromere protein B dimerisation domain" ]

5

[ "CENPB" ]

[ 583 ]

[ 599 ]

[ "D" ]

7

DP02466

Q12432

UPI0000052F18

Chromatin modification-related protein EAF3

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

401

0.024938

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2021_06

2019-12-10T16:02:48.291Z

fquaglia

UniRef100_Q12432

UniRef90_Q12432

UniRef50_Q12432

MVDLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLANEAKEAKKSLLEQQKKKKLSTSLGGPSNGGKRKGDSRSNASISKSTSQSFLTSSVSGRKSGRSSANSLHPGSSLRSSSDQNGNDDRRRSSSLSPNMLHHIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVSQELESPGSQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLKKSSKDQKPL...

1

[ "DP02466r001" ]

[ 44 ]

[ 53 ]

[ 10 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "18984594" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:3E9F", "PDB:3E9G" ]

[ "gene3D", "pfam", "pfam" ]

[ "G3DSA:1.10.274.30", "PF05712", "PF22732" ]

[ "G3DSA:1.10.274.30", "MRG", "MSL3 chromodomain-like" ]

3

[ "EAF3", "YP9367.03C", "YPR023C" ]

[ 44 ]

[ 53 ]

[ "D" ]

3

DP02467

P51617

UPI0000146573

Interleukin-1 receptor-associated kinase 1

Homo sapiens

9,606

712

0.043539

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-10T17:05:12.262Z

fquaglia

UniRef100_P51617

UniRef90_P51617

UniRef50_P51617

MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILL...

3

[ "DP02467r001", "DP02467r002", "DP02467r003" ]

[ 449, 367, 367 ]

[ 463, 382, 382 ]

[ 15, 16, 16 ]

[ "disorder", "disorder", "phosphorylation display site" ]

[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000045" ]

[ "Structural state", "Structural state", "Disorder function" ]

[ "ECO:0006220", "ECO:0006220", "ECO:0005670" ]

[ "29208712", "29208712", "29208712" ]

[ "pmid", "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:6BFN" ]

[ "pfam", "pfam" ]

[ "PF00069", "PF00531" ]

[ "Protein kinase domain", "Death domain" ]

2

[ "IRAK", "IRAK1" ]

[ 367, 449 ]

[ 382, 463 ]

[ "D", "D" ]

6

DP02468

P17480

UPI000013797C

Nucleolar transcription factor 1

Homo sapiens

9,606

764

0.018325

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2023_06

2019-12-11T10:45:04.442Z

fquaglia

UniRef100_P17480

UniRef90_P17480

UniRef50_P17480

MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVP...

1

[ "DP02468r001" ]

[ 547 ]

[ 560 ]

[ 14 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006165" ]

[ "17505112" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:2HDZ" ]

[ "gene3D", "gene3D", "gene3D", "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.10.30.10", "G3DSA:1.10.30.10", "G3DSA:1.10.30.10", "G3DSA:1.10.30.10", "G3DSA:1.10.30.10", "G3DSA:1.10.30.10", "PF00505", "PF00505", "PF00505", "PF09011", "PF14887" ]

[ "High mobility group box domain", "High mobility group box domain", "High mobility group box domain", "High mobility group box domain", "High mobility group box domain", "High mobility group box domain", "HMG (high mobility group) box", "HMG (high mobility group) box", "HMG (high mobility group) box...

11

[ "UBF", "UBF1", "UBTF" ]

[ 547 ]

[ 560 ]

[ "D" ]

9

DP02470

Q12495

UPI0000126D75

Chromatin assembly factor 1 subunit p90

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

559,292

606

0.10396

[]

[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]

2023_12

2019-12-11T11:34:19.345Z

fquaglia

UniRef100_Q12495

UniRef90_Q12495

UniRef50_Q12495

MEQHLKSIPLQDDTKKKGILSFFQNTTTVKSNKFLTKEKDVITLDDPKEDVSGPMIETVKQETMKSINKECADEMKTTPKKANAEDKLLCYKNSPIQSTKYDRNTNKQVPNGNIIAIETKSRSSSPCSKRELSSSKKEEAKREKELKKQQRAEEKHRKELLRQEEKKKKELKVEEERQRRAELKKQKEEEKRRKEEARLEAKRRKEEERLKKEEEIRLKEEAKERAQSRIGNFFKKLSDSNTPVVEKSDYEKFFLPFYAKDGVRVSNKWKLTKVELEGSKRKIDDELLNSKDKTSSDDLLNWLQSRRLPRGHKIKRKAVD...

1

[ "DP02470r001" ]

[ 457 ]

[ 519 ]

[ 63 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "27690308" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:5JBM" ]

[ "pfam", "pfam", "pfam" ]

[ "PF11600", "PF12253", "PF21796" ]

[ "Chromatin assembly factor 1 complex p150 subunit, acidic region", "Chromatin assembly factor 1 subunit A dimerization domain", "Chromatin assembly factor 1 subunit Cac1, C-terminal domain" ]

3

[ "CAC1", "RLF2", "YP9531.12", "YPR018W" ]

[ 457 ]

[ 519 ]

[ "D" ]

9

DP02471

Q96G97

UPI0000070140

Seipin

Homo sapiens

9,606

398

0.59799

[ "NDDs-related proteins" ]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-11T11:51:08.373Z

fquaglia

UniRef100_Q96G97

UniRef90_Q96G97

UniRef50_Q96G97

MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGT...

2

[ "DP02471r001", "DP02471r002" ]

[ 2, 220 ]

[ 60, 398 ]

[ 59, 179 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006224", "ECO:0006224" ]

[ "30293840", "30293840" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:6DS5" ]

[ "pfam" ]

[ "PF06775" ]

[ "Putative adipose-regulatory protein (Seipin)" ]

1

[ "BSCL2" ]

[ 2, 220 ]

[ 60, 398 ]

[ "D", "D" ]

5

DP02472

Q3U182

UPI00005ACFD0

CREB-regulated transcription coactivator 2

Mus musculus

10,090

692

0.052023

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]

2023_12

2019-12-11T12:20:17.543Z

fquaglia

UniRef100_Q3U182

UniRef90_Q3U182

UniRef50_Q3U182

MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDARRMVSPLRRYPRHIDSSPYSPAYLSPPPESGWRRMMPWGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGGFLDGEMDAKVPAIEENVVDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGI...

2

[ "DP02472r001", "DP02472r002" ]

[ 1, 59 ]

[ 14, 80 ]

[ 14, 22 ]

[ "disorder", "disorder" ]

[ "IDPO:0000002", "IDPO:0000002" ]

[ "Structural state", "Structural state" ]

[ "ECO:0006220", "ECO:0006220" ]

[ "29733854", "29733854" ]

[ "pmid", "pmid" ]

[ "Federica Quaglia", "Federica Quaglia" ]

[ "PDB:5ZKO" ]

[ "pfam", "pfam", "pfam" ]

[ "PF12884", "PF12885", "PF12886" ]

[ "Transducer of regulated CREB activity, N terminus", "Transducer of regulated CREB activity middle domain", "Transducer of regulated CREB activity, C terminus" ]

3

[ "Crtc2", "Torc2" ]

[ 1, 59 ]

[ 14, 80 ]

[ "D", "D" ]

9

DP02473

Q15642

UPI000016B11F

Cdc42-interacting protein 4

Homo sapiens

9,606

601

0.024958

[]

[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]

2021_06

2019-12-11T12:36:26.255Z

fquaglia

UniRef100_Q15642

UniRef90_Q15642

UniRef50_Q15642

MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSLGTPSDGRPELRGPGRSRTKR...

1

[ "DP02473r001" ]

[ 289 ]

[ 303 ]

[ 15 ]

[ "disorder" ]

[ "IDPO:0000002" ]

[ "Structural state" ]

[ "ECO:0006220" ]

[ "17512409" ]

[ "pmid" ]

[ "Federica Quaglia" ]

[ "PDB:2EFK" ]

[ "gene3D", "pfam", "pfam", "pfam" ]

[ "G3DSA:1.20.1270.60", "PF00018", "PF00611", "PF25610" ]

[ "Arfaptin homology (AH) domain/BAR domain", "SH3 domain", "Fes/CIP4, and EFC/F-BAR homology domain", "TOCA family HR1 domain" ]

4

[ "CIP4", "STOT", "STP", "TRIP10" ]

[ 289 ]

[ 303 ]

[ "D" ]

7