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disprot_id
string
accession
string
uniparc
string
name
string
organism
string
ncbi_taxon_id
int64
length
int64
disorder_content
float64
dataset_labels
list
taxonomy
list
released
string
date
string
creator
string
uniref100
string
uniref90
string
uniref50
string
sequence
string
region_count
int64
region_ids
list
region_starts
list
region_ends
list
region_lengths
list
region_terms
list
region_term_ids
list
region_namespaces
list
evidence_codes
list
reference_ids
list
reference_sources
list
curator_names
list
cross_refs
list
feature_databases
list
feature_ids
list
feature_names
list
feature_count
int64
gene_names
list
consensus_starts
list
consensus_ends
list
consensus_types
list
split_bucket
int64
DP02707
P25891
UPI0000034B75
Ribosome-inactivating protein 3
Zea mays
4,577
300
0.056667
[]
[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "Liliopsida", "Poales", "Poaceae", "PACMAD clade", "Panicoideae", "Andropogonodae", "Andropogoneae", "Tripsacinae", "Zea" ]
2021_06
2020-03-24T19:29:20.854Z
fquaglia
UniRef100_P25891
UniRef90_P25891
UniRef50_P10593
MAEITLEPSDLMAQTNKRIVPKFTEIFPVEDANYPYSAFIASVRKDVIKHCTDHKGIFQPVLPPEKKVPELWLYTELKTRTSSITLAIRMDNLYLVGFRTPGGVWWEFGKDGDTHLLGDNPRWLGFGGRYQDLIGNKGLETVTMGRAEMTRAVNDLAKKKKMATLEEEEVQMQMQMPEAADLAAAAAADPQADTKSKLVKLVVMVCEGLRFNTVSRTVDAGFNSQHGVTLTVTQGKQVQKWDRISKAAFEWADHPTAVIPDMQKLGIKDKNEAARIVALVKNQTTACATAASADNDDDEA
2
[ "DP02707r001", "DP02707r002" ]
[ 163, 163 ]
[ 179, 179 ]
[ 17, 17 ]
[ "disorder", "molecular function regulator" ]
[ "IDPO:0000002", "GO:0098772" ]
[ "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "17855394", "17855394" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2PQG" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:3.40.420.10", "G3DSA:4.10.470.10", "PF00161" ]
[ "Ricin (A subunit), domain 1", "Ricin (A Subunit), domain 2", "Ribosome inactivating protein" ]
3
[ "CRIP3" ]
[ 163 ]
[ 179 ]
[ "D" ]
6
DP02709
P04035
UPI000012C9E2
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Homo sapiens
9,606
888
0.031532
[ "Age-related disorders proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-25T09:49:35.080Z
fquaglia
UniRef100_P04035
UniRef90_P04035
UniRef50_P04035
MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDI...
3
[ "DP02709r001", "DP02709r002", "DP02709r003" ]
[ 861, 861, 861 ]
[ 888, 888, 888 ]
[ 28, 28, 28 ]
[ "disorder", "flexible C-terminal tail", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000031", "GO:0098772" ]
[ "Structural state", "Disorder function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "11349148", "11349148", "11349148" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1HW8", "PDB:1HW9", "PDB:1HWI", "PDB:1HWJ", "PDB:1HWK", "PDB:1HWL" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.30.70.420", "G3DSA:3.90.770.10", "G3DSA:1.10.3270.10", "PF00368", "PF12349" ]
[ "G3DSA:3.30.70.420", "3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2", "HMGR, N-terminal domain", "Hydroxymethylglutaryl-coenzyme A reductase", "Sterol-sensing domain of SREBP cleavage-activation" ]
5
[ "HMGCR" ]
[ 861 ]
[ 888 ]
[ "D" ]
9
DP02711
Q9V6K1
UPI0000083289
Tripeptidyl-peptidase 2
Drosophila melanogaster
7,227
1,441
0.067314
[]
[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]
2021_06
2020-03-25T11:30:38.128Z
fquaglia
UniRef100_Q9V6K1
UniRef90_Q9V6K1
UniRef50_Q9V6K1
MFNRFRLVHKQLRLYKNFGLLGQKASVGLTLPIISLSRPYMAYMGTERSVVMITAPATKEFAESSERSNSSKKTTNKEQSDKSAESRMATSGIVESFPTGALVPKAETGVLNFLQKYPEYDGRDVTIAIFDSGVDPRATGLETLCDGKTVKVIERYDCSGCGDVDMKKKVTPDENGNIKGLSGNSLKLSPELMALNTDPEKAVRVGLKSFSDLLPSKVRNNIVAQAKLKHWDKPHKTATANASRKIVEFESQNPGEASKLPWDKKILKENLDFELEMLNSYEKVYGDIKTSYDCILFPTADGWLTIVDTTEQGDLDQALR...
3
[ "DP02711r001", "DP02711r002", "DP02711r003" ]
[ 408, 442, 1027 ]
[ 417, 456, 1098 ]
[ 10, 15, 72 ]
[ "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "20676100", "20676100", "20676100" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3LXU" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:3.40.50.200", "PF00082", "PF12580", "PF12583", "PF21223", "PF21316" ]
[ "Peptidase S8/S53 domain", "Subtilase family", "Tripeptidyl peptidase II", "Tripeptidyl peptidase II, C-terminal", "Tripeptidyl-peptidase II, first Ig-like domain", "TPPII, galactose-binding domain-like" ]
6
[ "CG3991", "TppII" ]
[ 408, 442, 1027 ]
[ 417, 456, 1098 ]
[ "D", "D", "D" ]
9
DP02712
Q9H3P2
UPI000006DE29
Negative elongation factor A
Homo sapiens
9,606
528
0.643939
[ "Condensates-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-25T13:50:33.018Z
fquaglia
UniRef100_Q9H3P2
UniRef90_Q9H3P2
UniRef50_Q9H3P2
MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHGLSSAVKLKLLLGTLHLPRRTVDEMKGALMEIIQLASLDSDPWVLMVADILKSFPDTGSLNLELEEQNPNVQDILGELREKVGECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTAPSVFSPTGNRTPIPPSRTLLRKERGVKLLDISELDMVGAGREAKRRRKTLDAEVVEKPAKEETVVENATPDYAAGLVSTQKLGSLNNEPALP...
6
[ "DP02712r001", "DP02712r002", "DP02712r003", "DP02712r004", "DP02712r005", "DP02712r006" ]
[ 189, 189, 189, 189, 189, 189 ]
[ 528, 528, 528, 528, 528, 528 ]
[ 340, 340, 340, 340, 340, 340 ]
[ "disorder", "protein binding", "molecular adaptor activity", "molecular adaptor activity", "molecular adaptor activity", "molecular adaptor activity" ]
[ "IDPO:0000002", "GO:0005515", "GO:0060090", "GO:0060090", "GO:0060090", "GO:0060090" ]
[ "Structural state", "Molecular function", "Molecular function", "Molecular function", "Molecular function", "Molecular function" ]
[ "ECO:0006224", "ECO:0006208", "ECO:0006208", "ECO:0001170", "ECO:0001170", "ECO:0006208" ]
[ "30135580", "30135580", "30135580", "30135580", "30135580", "30135580" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Edoardo Salladini", "Edoardo Salladini", "Federica Quaglia" ]
[ "PDB:6GML" ]
[ "pfam" ]
[ "PF23553" ]
[ "NELF-A N-terminal domain" ]
1
[ "NELFA", "P/OKcl.15", "WHSC2" ]
[ 189 ]
[ 528 ]
[ "D" ]
1
DP02713
P18615
UPI000016AF7C
Negative elongation factor E
Homo sapiens
9,606
380
0.592105
[ "Condensates-related proteins", "RNA-binding proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-03-25T15:42:42.186Z
fquaglia
UniRef100_P18615
UniRef90_P18615
UniRef50_P18615
MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQV...
1
[ "DP02713r001" ]
[ 139 ]
[ 363 ]
[ 225 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006224" ]
[ "30135580" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:6GML" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.30.70.330", "PF00076" ]
[ "G3DSA:3.30.70.330", "RNA recognition motif" ]
2
[ "NELFE", "RD", "RDBP" ]
[ 139 ]
[ 363 ]
[ "D" ]
2
DP02714
O60880
UPI0000000D0B
SH2 domain-containing protein 1A
Homo sapiens
9,606
128
0.203125
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-25T17:35:10.747Z
fquaglia
UniRef100_O60880
UniRef90_O60880
UniRef50_O60880
MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIREDPDVCLKAP
1
[ "DP02714r001" ]
[ 103 ]
[ 128 ]
[ 26 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006165" ]
[ "11823424" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1KA6", "PDB:1KA7" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.30.505.10", "PF00017" ]
[ "SH2 domain", "SH2 domain" ]
2
[ "DSHP", "SAP", "SH2D1A" ]
[ 103 ]
[ 128 ]
[ "D" ]
8
DP02715
P00452
UPI0000112BE0
Ribonucleoside-diphosphate reductase 1 subunit alpha
Escherichia coli (strain K12)
83,333
761
0.032852
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2021_06
2020-03-25T20:11:58.107Z
fquaglia
UniRef100_P00452
UniRef90_P00452
UniRef50_P00452
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLK...
2
[ "DP02715r001", "DP02715r002" ]
[ 737, 737 ]
[ 761, 761 ]
[ 25, 25 ]
[ "disorder", "protein folding chaperone" ]
[ "IDPO:0000002", "GO:0044183" ]
[ "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "8052308", "8052308" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1RLR" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00317", "PF02867", "PF03477" ]
[ "Ribonucleotide reductase, all-alpha domain", "Ribonucleotide reductase, barrel domain", "ATP cone domain" ]
3
[ "JW2228", "b2234", "dnaF", "nrdA" ]
[ 737 ]
[ 761 ]
[ "D" ]
7
DP02716
P0A873
UPI0000137412
tRNA (guanine-N(1)-)-methyltransferase
Escherichia coli (strain K12)
83,333
255
0.043137
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2021_06
2020-03-26T09:40:36.716Z
fquaglia
UniRef100_A7ZQ47
UniRef90_A4WDH2
UniRef50_Q7MBD6
MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
2
[ "DP02716r001", "DP02716r002" ]
[ 162, 162 ]
[ 172, 172 ]
[ 11, 11 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "14583191", "14583191" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1P9P" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:1.10.1270.20", "G3DSA:3.40.1280.10", "PF01746" ]
[ "tRNA(m1g37)methyltransferase, domain 2", "G3DSA:3.40.1280.10", "tRNA (Guanine-1)-methyltransferase TrmD" ]
3
[ "JW2588", "b2607", "trmD" ]
[ 162 ]
[ 172 ]
[ "D" ]
6
DP02717
O95071
UPI0000129BCB
E3 ubiquitin-protein ligase UBR5
Homo sapiens
9,606
2,799
0.003573
[ "Cancer-related proteins", "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2022_06
2020-03-26T10:01:16.045Z
xcastro
UniRef100_O95071
UniRef90_O95071
UniRef50_O95071
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSELLRERESVLRLRER...
1
[ "DP02717r001" ]
[ 2738 ]
[ 2747 ]
[ 10 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "23027739" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:3PT3" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.130.10.30", "PF00632", "PF00658", "PF11547" ]
[ "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II", "HECT-domain (ubiquitin-transferase)", "MLLE domain", "E3 ubiquitin ligase EDD" ]
4
[ "EDD", "EDD1", "HYD", "KIAA0896", "UBR5" ]
[ 2738 ]
[ 2747 ]
[ "D" ]
9
DP02718
Q8ST83
UPI000008014A
Polycomb protein PHO
Drosophila melanogaster
7,227
520
0.201923
[]
[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]
2023_12
2020-03-26T10:22:18.657Z
fquaglia
UniRef100_Q8ST83
UniRef90_Q8ST83
UniRef50_Q8ST83
MAYERFGIILQSEQYDEDIGNTKVNQKMNEGNHYDLHRKNAFDRIIHSESKKGDNVINYNIHENDKIKAADNIFSSKLKMNPNMSYEMNINCFKNIGYGENQETSKVLTNSLSNNDINTEESGVVDKNSPFLTLGTTILNSNGKSRRWEQKLVHIKTMEGEFSVTMWASGISDDEYSGSDQIVGASDLLKGKEEFGIDGFTSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQENNISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNHTGNTGDLHALPSSVPFRIGLHEGQVND...
3
[ "DP02718r001", "DP02718r002", "DP02718r003" ]
[ 116, 171, 171 ]
[ 144, 246, 246 ]
[ 29, 76, 76 ]
[ "disorder", "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "24186981", "24186981", "24186981" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4C5E", "PDB:4C5G", "PDB:4C5H" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00096", "PF00096", "PF00096" ]
[ "Zinc finger, C2H2 type", "Zinc finger, C2H2 type", "Zinc finger, C2H2 type" ]
3
[ "CG17743", "pho" ]
[ 116, 171 ]
[ 144, 246 ]
[ "D", "D" ]
5
DP02719
Q53FT3
UPI000050A8EF
Protein Hikeshi
Homo sapiens
9,606
197
0.096447
[ "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-26T11:40:46.719Z
fquaglia
UniRef100_Q53FT3
UniRef90_Q53FT3
UniRef50_Q53FT3
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYESINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTPSPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
1
[ "DP02719r001" ]
[ 88 ]
[ 106 ]
[ 19 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "25760597" ]
[ "pmid" ]
[ "Victoria Nugnes" ]
[ "PDB:3WW0" ]
[ "pfam", "pfam" ]
[ "PF05603", "PF21057" ]
[ "Hikeshi-like, N-terminal domain", "Hikeshi-like, C-terminal domain" ]
2
[ "C11orf73", "HIKESHI", "HSPC138", "HSPC179", "HSPC248" ]
[ 88 ]
[ 106 ]
[ "D" ]
1
DP02721
P32357
UPI0000053112
A1 cistron-splicing factor AAR2
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
355
0.053521
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-03-26T12:11:48.224Z
fquaglia
UniRef100_P32357
UniRef90_P32357
UniRef50_P32357
MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVIHFQHADNSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQMMVSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQENELLKSSLQKAGSKMEAKNEDDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNSSNYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEILYYQIKTLPEQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELLGKD...
2
[ "DP02721r001", "DP02721r002" ]
[ 153, 153 ]
[ 171, 171 ]
[ 19, 19 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "21764848", "21764848" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3SBS", "PDB:3SBT" ]
[ "gene3D", "gene3D", "pfam", "pfam" ]
[ "G3DSA:1.25.40.550", "G3DSA:2.60.34.20", "PF05282", "PF20981" ]
[ "G3DSA:1.25.40.550", "G3DSA:2.60.34.20", "AAR2 C-terminal repeat region", "AAR2 N-terminal domain" ]
4
[ "AAR2", "YBL06.06", "YBL0611", "YBL074C" ]
[ 153 ]
[ 171 ]
[ "D" ]
2
DP02723
Q8VDP3
UPI00000E6848
[F-actin]-monooxygenase MICAL1
Mus musculus
10,090
1,048
0.01813
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-03-26T12:42:40.873Z
fquaglia
UniRef100_Q8VDP3
UniRef90_Q8VDP3
UniRef50_Q8TDZ2-2
MASPASTNPAHDHFETFVQAQLCQDVLSSFQGLCRALGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQPVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVKFTGLQPPPRKGSGWRAQLQPNPPAQLASYEFDVLISAAGGKFVPEGFTIREMRGKLAIGITANFVNGRTVEETQVPEISGVARIYNQKFFQSLLKATGIDLENIVYYKDETHYFVMTAKKQCLLRLGVLRQDLSETDQLL...
2
[ "DP02723r001", "DP02723r002" ]
[ 487, 487 ]
[ 505, 505 ]
[ 19, 19 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "26935886", "26935886" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4TXI" ]
[ "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:3.50.50.60", "G3DSA:1.10.418.10", "PF00307", "PF01494", "PF12130", "PF25413" ]
[ "FAD/NAD(P)-binding domain", "Calponin-like domain", "Calponin homology (CH) domain", "FAD binding domain", "Bivalent Mical/EHBP Rab binding domain", "Mical, Rossman domain" ]
6
[ "Mical", "Mical1", "Nical" ]
[ 487 ]
[ 505 ]
[ "D" ]
3
DP02724
Q13838
UPI0000001D0B
Spliceosome RNA helicase DDX39B
Homo sapiens
9,606
428
0.025701
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-27T09:41:23.972Z
fquaglia
UniRef100_Q13838
UniRef90_Q13838
UniRef50_Q13838
MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRG...
2
[ "DP02724r001", "DP02724r002" ]
[ 34, 34 ]
[ 44, 44 ]
[ 11, 11 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0007691" ]
[ "15296731", "15296731" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1T6N" ]
[ "pfam", "pfam" ]
[ "PF00270", "PF00271" ]
[ "DEAD/DEAH box helicase", "Helicase conserved C-terminal domain" ]
2
[ "BAT1", "DDX39B", "UAP56" ]
[ 34 ]
[ 44 ]
[ "D" ]
5
DP02726
Q42521
UPI000016DA16
Glutamate decarboxylase 1
Arabidopsis thaliana
3,702
502
0.129482
[]
[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "eudicotyledons", "Gunneridae", "Pentapetalae", "rosids", "malvids", "Brassicales", "Brassicaceae", "Camelineae", "Arabidopsis" ]
2021_06
2020-03-27T10:20:40.723Z
fquaglia
UniRef100_Q42521
UniRef90_Q42521
UniRef50_Q42521
MVLSHAVSESDVSVHSTFASRYVRTSLPRFKMPENSIPKEAAYQIINDELMLDGNPRLNLASFVTTWMEPECDKLIMSSINKNYVDMDEYPVTTELQNRCVNMIAHLFNAPLEEAETAVGVGTVGSSEAIMLAGLAFKRKWQNKRKAEGKPVDKPNIVTGANVQVCWEKFARYFEVELKEVKLSEGYYVMDPQQAVDMVDENTICVAAILGSTLNGEFEDVKLLNDLLVEKNKETGWDTPIHVDAASGGFIAPFLYPELEWDFRLPLVKSINVSGHKYGLVYAGIGWVIWRNKEDLPEELIFHINYLGADQPTFTLNFSK...
7
[ "DP02726r001", "DP02726r002", "DP02726r003", "DP02726r004", "DP02726r005", "DP02726r006", "DP02726r007" ]
[ 1, 449, 449, 471, 471, 1, 471 ]
[ 11, 502, 470, 502, 502, 57, 502 ]
[ 11, 54, 22, 32, 32, 57, 32 ]
[ "disorder", "disorder", "flexible linker", "protein binding", "protein binding", "molecular adaptor activity", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033", "GO:0005515", "GO:0005515", "GO:0060090", "GO:0098772" ]
[ "Structural state", "Structural state", "Disorder function", "Molecular function", "Molecular function", "Molecular function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0007066", "ECO:0006210", "ECO:0006220", "ECO:0006218" ]
[ "19580813", "19580813", "19580813", "19580813", "19580813", "19580813", "19580813" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3HBX" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.40.640.10", "PF00282" ]
[ "Type I PLP-dependent aspartate aminotransferase-like (Major domain)", "Pyridoxal-dependent decarboxylase conserved domain" ]
2
[ "At5g17330", "GAD", "GAD1", "GDH1", "MKP11.30", "MKP11_18" ]
[ 1, 12, 449 ]
[ 11, 57, 502 ]
[ "D", "F", "D" ]
3
DP02728
P42166
UPI000013D709
Lamina-associated polypeptide 2, isoform alpha
Homo sapiens
9,606
694
0.086455
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-03-27T19:19:07.009Z
fquaglia
UniRef100_P42166
UniRef90_P42166
UniRef50_P42166
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNEEGKKKEHKKVKSTRDIVPFSELGTTPSGGGFFQGISFPEISTRPPLGSTELQAAKKVHTSKGDLPREPLVATNLPGRGQLQKLASERNLFISCKSSHDRCLEKSSSSSSQPEHSAMLVSTAASPSLIKETTTG...
2
[ "DP02728r001", "DP02728r002" ]
[ 51, 51 ]
[ 110, 110 ]
[ 60, 60 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006165", "ECO:0006165" ]
[ "11500367", "11500367" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1GJJ" ]
[ "gene3D", "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.720.40", "G3DSA:1.10.720.40", "PF03020", "PF08198", "PF11560" ]
[ "G3DSA:1.10.720.40", "G3DSA:1.10.720.40", "LEM domain", "Thymopoietin protein", "Lamina-associated polypeptide 2 alpha" ]
5
[ "LAP2", "TMPO" ]
[ 51 ]
[ 110 ]
[ "D" ]
3
DP02729
Q96EP1
UPI000006EA87
E3 ubiquitin-protein ligase CHFR
Homo sapiens
9,606
664
0.040663
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-31T08:43:38.476Z
fquaglia
UniRef100_Q96EP1
UniRef90_Q96EP1
UniRef50_Q96EP1
MERPEEGKQSPPPQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYESLSEKQGMTQESFEANKENVFHGTKDTSGAGAGRGADPRVPPSSPATQVCFEEPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC...
2
[ "DP02729r001", "DP02729r002" ]
[ 446, 446 ]
[ 472, 472 ]
[ 27, 27 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "20880844", "20880844" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2XOC", "PDB:2XOY", "PDB:2XOZ", "PDB:2XP0" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:3.30.40.10", "PF00498", "PF13923", "PF17979" ]
[ "Zinc/RING finger domain, C3HC4 (zinc finger)", "FHA domain", "Zinc finger, C3HC4 type (RING finger)", "Cysteine rich domain with multizinc binding regions" ]
4
[ "CHFR", "RNF196" ]
[ 446 ]
[ 472 ]
[ "D" ]
7
DP02730
Q6P1M3
UPI0000232A48
LLGL scribble cell polarity complex component 2
Homo sapiens
9,606
1,020
0.090196
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-31T09:42:19.759Z
fquaglia
UniRef100_Q6P1M3
UniRef90_Q6P1M3
UniRef50_Q6P1M3
MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHD...
5
[ "DP02730r001", "DP02730r002", "DP02730r003", "DP02730r004", "DP02730r005" ]
[ 471, 631, 631, 471, 631 ]
[ 484, 708, 708, 484, 708 ]
[ 14, 78, 78, 14, 78 ]
[ "disorder", "disorder", "flexible linker", "flexible linker", "phosphorylation display site" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033", "IDPO:0000033", "IDPO:0000045" ]
[ "Structural state", "Structural state", "Disorder function", "Disorder function", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0001230" ]
[ "31088962", "31088962", "31088962", "31088962", "31088962" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:6N8P", "PDB:6N8Q", "PDB:6N8R", "PDB:6N8S" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:2.130.10.10", "PF00400", "PF08366" ]
[ "YVTN repeat-like/Quinoprotein amine dehydrogenase", "WD domain, G-beta repeat", "LLGL2" ]
3
[ "LLGL2" ]
[ 471, 631 ]
[ 484, 708 ]
[ "D", "D" ]
9
DP02731
Q5U651
UPI000020283D
Ras-interacting protein 1
Homo sapiens
9,606
963
0.030114
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-03-31T14:00:21.803Z
fquaglia
UniRef100_Q5U651
UniRef90_Q5U651
UniRef50_Q5U651
MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAASVKSSSSDTGSRSSEPLPPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGTGTTGSSGAGGPGTPGGAQRWASEKKLPELAAGVAPEPPLATRATAPPGVLKIFGAGLASGANYKSVLATARSTARELVAEALERYGLAGSPGGGPGESSCVDAFALCDALGRPAAAGVGSGEWRAEHLRVLGDSERPLLVQELWRARPGWARRFELRGREEARRLEQEAFGAADSEGTGAPSWRPQKNRSRAASGGAALASPGPGTGSGAPAGSGGKERSEN...
4
[ "DP02731r001", "DP02731r002", "DP02731r003", "DP02731r004" ]
[ 187, 268, 268, 187 ]
[ 197, 285, 285, 197 ]
[ 11, 18, 18, 11 ]
[ "disorder", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006165", "ECO:0006165" ]
[ "27839947", "27839947", "27839947", "27839947" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5KHO", "PDB:5KHQ" ]
[ "pfam", "pfam" ]
[ "PF00788", "PF01843" ]
[ "Ras association (RalGDS/AF-6) domain", "DIL domain" ]
2
[ "RASIP1" ]
[ 187, 268 ]
[ 197, 285 ]
[ "D", "D" ]
3
DP02732
Q8IWJ2
UPI00000744D3
GRIP and coiled-coil domain-containing protein 2
Homo sapiens
9,606
1,684
0.013658
[ "Condensates-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2024_06
2020-03-31T14:39:42.684Z
fquaglia
UniRef100_Q8IWJ2
UniRef90_Q8IWJ2
UniRef50_Q8IWJ2
MEDLVQDGVASPATPGTGKSKLETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILL...
1
[ "DP02732r001" ]
[ 1547 ]
[ 1569 ]
[ 23 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "18243103" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:3BBP" ]
[ "pfam", "pfam" ]
[ "PF01465", "PF16704" ]
[ "GRIP domain", "Rab binding domain" ]
2
[ "GCC2", "KIAA0336", "RANBP2L4" ]
[ 1547 ]
[ 1569 ]
[ "D" ]
3
DP02733
P20340
UPI0000037BDB
Ras-related protein Rab-6A
Homo sapiens
9,606
208
0.153846
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-03-31T14:56:18.159Z
fquaglia
UniRef100_P20340
UniRef90_P20340
UniRef50_P20340
MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC
2
[ "DP02733r001", "DP02733r002" ]
[ 175, 175 ]
[ 206, 206 ]
[ 32, 32 ]
[ "disorder", "localization" ]
[ "IDPO:0000002", "GO:0051179" ]
[ "Structural state", "Biological process" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "18243103", "18243103" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3BBP" ]
[ "pfam" ]
[ "PF00071" ]
[ "Ras family" ]
1
[ "RAB6", "RAB6A" ]
[ 175 ]
[ 206 ]
[ "D" ]
2
DP02734
P21517
UPI000016F2CF
Maltodextrin glucosidase
Escherichia coli (strain K12)
83,333
604
0.236755
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2023_12
2020-03-31T15:36:32.668Z
fquaglia
UniRef100_P21517
UniRef90_P21517
UniRef50_P21517
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIV...
4
[ "DP02734r001", "DP02734r002", "DP02734r003", "DP02734r005" ]
[ 1, 1, 1, 419 ]
[ 131, 131, 131, 430 ]
[ 131, 131, 131, 12 ]
[ "disorder", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0007691", "ECO:0006200", "ECO:0006220" ]
[ "27317979", "27317979", "27317979", "27317979" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5BN7" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.40.1180", "PF00128", "PF00128", "PF02903" ]
[ "Golgi alpha-mannosidase II", "Alpha amylase, catalytic domain", "Alpha amylase, catalytic domain", "Alpha amylase, N-terminal ig-like domain" ]
4
[ "JW0393", "b0403", "malZ" ]
[ 1, 419 ]
[ 131, 430 ]
[ "D", "D" ]
6
DP02735
P07355
UPI0000125B76
Annexin A2
Homo sapiens
9,606
339
0.094395
[ "Extracellular matrix proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-03-31T16:49:43.108Z
fquaglia
UniRef100_P07355
UniRef90_P07355
UniRef50_P07355
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ...
8
[ "DP02735r001", "DP02735r002", "DP02735r004", "DP02735r005", "DP02735r006", "DP02735r007", "DP02735r008", "DP02735r009" ]
[ 2, 22, 2, 2, 2, 2, 2, 2 ]
[ 33, 26, 33, 33, 15, 33, 33, 33 ]
[ 32, 5, 32, 32, 14, 32, 32, 32 ]
[ "disorder", "phosphorylation display site", "disorder to order", "protein binding", "protein binding", "protein binding", "molecular function regulator", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000045", "IDPO:0000011", "GO:0005515", "GO:0005515", "GO:0005515", "GO:0098772", "GO:0098772" ]
[ "Structural state", "Disorder function", "Structural transition", "Molecular function", "Molecular function", "Molecular function", "Molecular function", "Molecular function" ]
[ "ECO:0006220", "ECO:0001230", "ECO:0005670", "ECO:0005670", "ECO:0006277", "ECO:0005647", "ECO:0006319", "ECO:0006317" ]
[ "28669632", "28669632", "28669632", "28669632", "28669632", "28669632", "28669632", "28669632" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5LPU", "PDB:5LPX", "PDB:5LQ0", "PDB:5LQ2" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.220.10", "PF00191", "PF00191", "PF00191", "PF00191" ]
[ "Annexin", "Annexin", "Annexin", "Annexin", "Annexin" ]
5
[ "ANX2", "ANX2L4", "ANXA2", "CAL1H", "LPC2D" ]
[ 2 ]
[ 33 ]
[ "T" ]
9
DP02736
Q04049
UPI000006B8F4
DNA polymerase eta
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
632
0.19462
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-03-31T17:42:38.259Z
fquaglia
UniRef100_Q04049
UniRef90_Q04049
UniRef50_Q04049
MSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKEDPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGKFEITSFWTLGGVLGKELIDVL...
3
[ "DP02736r001", "DP02736r002", "DP02736r003" ]
[ 510, 510, 510 ]
[ 528, 632, 632 ]
[ 19, 123, 123 ]
[ "disorder", "disorder", "molecular adaptor activity" ]
[ "IDPO:0000002", "IDPO:0000002", "GO:0060090" ]
[ "Structural state", "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006210", "ECO:0006218" ]
[ "29385534", "29385534", "29385534" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5VTP" ]
[ "gene3D", "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.30.1490.100", "G3DSA:3.30.70.270", "PF00817", "PF11799" ]
[ "DNA polymerase, Y-family, little finger domain", "G3DSA:3.30.70.270", "impB/mucB/samB family", "impB/mucB/samB family C-terminal domain" ]
4
[ "DBH1", "RAD30", "YDR419W" ]
[ 510 ]
[ 632 ]
[ "D" ]
6
DP02737
Q9NWW9
UPI000012CBE3
Phospholipase A and acyltransferase 2
Homo sapiens
9,606
162
0.074074
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-06T08:52:58.057Z
fquaglia
UniRef100_Q9NWW9
UniRef90_Q9NWW9
UniRef50_Q9NWW9
MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
2
[ "DP02737r001", "DP02737r002" ]
[ 40, 40 ]
[ 51, 51 ]
[ 12, 12 ]
[ "disorder", "localization" ]
[ "IDPO:0000002", "GO:0051179" ]
[ "Structural state", "Biological process" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "22605381", "22605381" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4DPZ" ]
[ "pfam" ]
[ "PF04970" ]
[ "Lecithin retinol acyltransferase" ]
1
[ "HRASLS2", "PLAAT2" ]
[ 40 ]
[ 51 ]
[ "D" ]
5
DP02738
P08581
UPI000016AD2F
Hepatocyte growth factor receptor
Homo sapiens
9,606
1,390
0.014388
[ "Cancer-related proteins", "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-06T09:51:31.068Z
fquaglia
UniRef100_P08581
UniRef90_P08581
UniRef50_P08581
MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAA...
4
[ "DP02738r001", "DP02738r002", "DP02738r003", "DP02738r004" ]
[ 1225, 1225, 1225, 1225 ]
[ 1244, 1239, 1244, 1244 ]
[ 20, 15, 20, 20 ]
[ "disorder", "order to disorder", "phosphorylation display site", "molecular function activator activity" ]
[ "IDPO:0000002", "IDPO:0000014", "IDPO:0000045", "GO:0140677" ]
[ "Structural state", "Structural transition", "Disorder function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005801", "ECO:0006220" ]
[ "21247903", "21247903", "21247903", "21247903" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:3Q6U", "PDB:3Q6W", "PDB:3R7O" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "G3DSA:2.130.10.10", "PF01403", "PF01437", "PF01833", "PF01833", "PF01833", "PF07714" ]
[ "Immunoglobulins", "Immunoglobulins", "YVTN repeat-like/Quinoprotein amine dehydrogenase", "Sema domain", "Plexin repeat", "IPT/TIG domain", "IPT/TIG domain", "IPT/TIG domain", "Protein tyrosine and serine/threonine kinase" ]
9
[ "MET" ]
[ 1225, 1240 ]
[ 1239, 1244 ]
[ "T", "D" ]
3
DP02739
P45352
UPI0000112C76
Thymidylate synthase
Rattus norvegicus
10,116
307
0.065147
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]
2020_12
2020-04-06T16:43:21.296Z
fquaglia
UniRef100_P45352
UniRef90_P04818-2
UniRef50_P04818-2
MLVEGSELQSGAQQPRTEAPQHGELQYLRQVEHIMRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGADYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV
1
[ "DP02739r001" ]
[ 1 ]
[ 20 ]
[ 20 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "9894005" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1RTS", "PDB:2TSR" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.30.572.10", "PF00303" ]
[ "Thymidylate synthase/dCMP hydroxymethylase domain", "Thymidylate synthase" ]
2
[ "Tyms" ]
[ 1 ]
[ 20 ]
[ "D" ]
1
DP02741
P09951
UPI000004368E
Synapsin-1
Rattus norvegicus
10,116
704
0.15625
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]
2021_06
2020-04-07T17:23:44.475Z
fquaglia
UniRef100_P09951
UniRef90_O88935
UniRef50_O88935
MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSAAASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIG...
4
[ "DP02741r001", "DP02741r002", "DP02741r004", "DP02741r005" ]
[ 2, 7, 53, 85 ]
[ 111, 11, 58, 89 ]
[ 110, 5, 6, 5 ]
[ "disorder", "phosphorylation display site", "glycosylation display site", "glycosylation display site" ]
[ "IDPO:0000002", "IDPO:0000045", "IDPO:0000041", "IDPO:0000041" ]
[ "Structural state", "Disorder function", "Disorder function", "Disorder function" ]
[ "ECO:0006220", "ECO:0007689", "ECO:0007680", "ECO:0007680" ]
[ "14688264", "10571231", "10386995", "10386995" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1PK8", "PDB:1PX2" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:3.30.1490.20", "PF02078", "PF02750", "PF10581" ]
[ "ATP-grasp fold, A domain", "Synapsin pre-ATP-grasp domain", "Synapsin, ATP binding domain", "Synapsin N-terminal domain" ]
4
[ "Syn1" ]
[ 2 ]
[ 111 ]
[ "D" ]
6
DP02742
P06756
UPI000013D12E
Integrin alpha-V
Homo sapiens
9,606
1,048
0.028626
[ "Cancer-related proteins", "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-07T18:18:20.167Z
fquaglia
UniRef100_P06756
UniRef90_P06756
UniRef50_P06756
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDY...
2
[ "DP02742r001", "DP02742r002" ]
[ 868, 868 ]
[ 897, 897 ]
[ 30, 30 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "23106217", "23106217" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4G1M" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.130.10.130", "PF00357", "PF01839", "PF01839", "PF01839", "PF08441", "PF20805", "PF20806" ]
[ "Integrin alpha, N-terminal", "Integrin alpha cytoplasmic region", "FG-GAP repeat", "FG-GAP repeat", "FG-GAP repeat", "Integrin alpha Ig-like domain 1", "Integrin alpha Ig-like domain 2", "Integrin alpha Ig-like domain 3" ]
8
[ "ITGAV", "MSK8", "VNRA", "VTNR" ]
[ 868 ]
[ 897 ]
[ "D" ]
5
DP02744
Q92574
UPI000016A7B6
Hamartin
Homo sapiens
9,606
1,164
0.012887
[ "Autophagy-related proteins", "Cancer-related proteins", "NDDs-related proteins", "Age-related disorders proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-08T23:08:07.447Z
fquaglia
UniRef100_Q92574
UniRef90_Q92574
UniRef50_Q92574
MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLL...
5
[ "DP02744r001", "DP02744r002", "DP02744r003", "DP02744r004", "DP02744r005" ]
[ 978, 939, 939, 939, 939 ]
[ 992, 992, 992, 992, 992 ]
[ 15, 54, 54, 54, 54 ]
[ "disorder", "protein binding", "protein binding", "protein binding", "TSC1-TSC2 complex" ]
[ "IDPO:0000002", "GO:0005515", "GO:0005515", "GO:0005515", "GO:0033596" ]
[ "Structural state", "Molecular function", "Molecular function", "Molecular function", "Cellular component" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005647", "ECO:0006077", "ECO:0005670" ]
[ "26893383", "26893383", "26893383", "26893383", "26893383" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Victoria Nugnes", "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:5EJC" ]
[ "pfam" ]
[ "PF04388" ]
[ "Hamartin protein" ]
1
[ "KIAA0243", "TSC", "TSC1" ]
[ 939, 978 ]
[ 977, 992 ]
[ "F", "D" ]
3
DP02745
P05231
UPI000002C4A6
Interleukin-6
Homo sapiens
9,606
212
0.089623
[ "Extracellular matrix proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-08T23:39:16.558Z
fquaglia
UniRef100_P05231
UniRef90_P05231
UniRef50_P05231
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
2
[ "DP02745r001", "DP02745r002" ]
[ 28, 28 ]
[ 46, 46 ]
[ 19, 19 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006165", "ECO:0006220" ]
[ "9159484", "9118960" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Edoardo Salladini" ]
[ "PDB:1ALU", "PDB:1IL6", "PDB:2IL6" ]
[ "pfam" ]
[ "PF00489" ]
[ "Interleukin-6/G-CSF/MGF family" ]
1
[ "IFNB2", "IL6" ]
[ 28 ]
[ 46 ]
[ "D" ]
5
DP02746
Q14565
UPI000016AAAD
Meiotic recombination protein DMC1/LIM15 homolog
Homo sapiens
9,606
340
0.297059
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-04-08T23:58:29.672Z
fquaglia
UniRef100_Q14565
UniRef90_Q14565
UniRef50_Q14565
MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPE...
3
[ "DP02746r001", "DP02746r002", "DP02746r003" ]
[ 271, 271, 1 ]
[ 289, 289, 82 ]
[ 19, 19, 82 ]
[ "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "23545642", "15125839", "15125839" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1V5W", "PDB:4HYY" ]
[ "pfam", "pfam" ]
[ "PF08423", "PF14520" ]
[ "Rad51", "Helix-hairpin-helix domain" ]
2
[ "DMC1", "DMC1H", "LIM15" ]
[ 1, 271 ]
[ 82, 289 ]
[ "D", "D" ]
7
DP02748
P36871
UPI0000131860
Phosphoglucomutase-1
Homo sapiens
9,606
562
0.021352
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-09T13:04:02.952Z
fquaglia
UniRef100_P36871
UniRef90_P36871
UniRef50_P36871
MVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSI...
1
[ "DP02748r001" ]
[ 256 ]
[ 267 ]
[ 12 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "26972339" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:5HSH" ]
[ "pfam", "pfam", "pfam", "pfam" ]
[ "PF02878", "PF02879", "PF02880", "PF24947" ]
[ "Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I", "Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II", "Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III", "Phosphoglucomutase-1, C-terminal domain" ]
4
[ "PGM1" ]
[ 256 ]
[ 267 ]
[ "D" ]
6
DP02749
P09041
UPI0000161CF4
Phosphoglycerate kinase 2
Mus musculus
10,090
417
0.035971
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-09T13:19:14.257Z
fquaglia
UniRef100_P09041
UniRef90_P09041
UniRef50_P09041
MALSAKLTLDKVDLKGKRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLMSHLGRPDGIPMPDKYSLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLENLRFHVEEEGKGKDSSGKKISADPAKVEAFQASLSKLGDVYVNDAFGTAHRAHSSTVGVNLPQKASGFLMKKELDYFSKALEKPERPFLAILGGAKVKDKIQLIKNMLDKVNFMIIGGGMAYTFLKELKNMQIGASLFDEEGATIVKEIMEKAEKNGVKIVFPVDFVTGDKFDENAKVGQATIESGIPSGWMGLDCGPES...
2
[ "DP02749r001", "DP02749r002" ]
[ 372, 372 ]
[ 386, 386 ]
[ 15, 15 ]
[ "disorder", "disorder to order" ]
[ "IDPO:0000002", "IDPO:0000011" ]
[ "Structural state", "Structural transition" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "18004764", "18004764" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2P9Q", "PDB:2PAA" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:3.40.50.1260", "G3DSA:3.40.50.1260", "PF00162" ]
[ "G3DSA:3.40.50.1260", "G3DSA:3.40.50.1260", "Phosphoglycerate kinase" ]
3
[ "Pgk-2", "Pgk2" ]
[ 372 ]
[ 386 ]
[ "T" ]
6
DP02750
P17109
UPI000016F2E6
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Escherichia coli (strain K12)
83,333
556
0.030576
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2021_06
2020-04-14T09:13:12.797Z
fquaglia
UniRef100_C4ZUA7
UniRef90_Q8XDX8
UniRef50_Q8XDX8
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAH...
3
[ "DP02750r001", "DP02750r002", "DP02750r003" ]
[ 472, 472, 472 ]
[ 488, 488, 488 ]
[ 17, 17, 17 ]
[ "disorder", "disorder to order", "disorder" ]
[ "IDPO:0000002", "IDPO:0000011", "IDPO:0000002" ]
[ "Structural state", "Structural transition", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "19703421", "19703421", "19338755" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3FLM", "PDB:3HWW", "PDB:3HWX" ]
[ "pfam", "pfam", "pfam" ]
[ "PF02775", "PF02776", "PF16582" ]
[ "Thiamine pyrophosphate enzyme, C-terminal TPP binding domain", "Thiamine pyrophosphate enzyme, N-terminal TPP binding domain", "Middle domain of thiamine pyrophosphate" ]
3
[ "JW5374", "b2264", "menD" ]
[ 472 ]
[ 488 ]
[ "T" ]
7
DP02751
Q03653
UPI000013B910
Protein EFR3
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
782
0.02046
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-14T09:54:46.472Z
fquaglia
UniRef100_Q03653
UniRef90_Q03653
UniRef50_Q03653
MQLSMRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVNSRRSKLEKVSTYLIKRSTSDLNHRRIGNIAVTLDLMNKIVLHCKENLNVFVKDFLYIMNKVLSNNNFNNDVSVVELIELAFSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSNPQLNHFVSKSVAYTISKFQERNPKFKTLSLEAALESNLGKRLSRTQTRTIGLDKAAEDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQSTPNKELLEFVCNGIPVQLRYIVILLLVRQLSDKDKNVNPIVSLK...
1
[ "DP02751r001" ]
[ 217 ]
[ 232 ]
[ 16 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "24360784" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:4N5A" ]
[ "pfam" ]
[ "PF21072" ]
[ "EFR3 protein" ]
1
[ "EFR3", "YM8261.06C", "YMR212C" ]
[ 217 ]
[ 232 ]
[ "D" ]
2
DP02753
Q13617
UPI0000154743
Cullin-2
Homo sapiens
9,606
745
0.05906
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-04-14T11:22:25.544Z
fquaglia
UniRef100_Q13617
UniRef90_Q13617
UniRef50_Q13617
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIH...
4
[ "DP02753r001", "DP02753r004", "DP02753r005", "DP02753r006" ]
[ 117, 117, 625, 645 ]
[ 134, 134, 634, 660 ]
[ 18, 18, 10, 16 ]
[ "disorder", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "25661653", "28591624", "28591624", "28591624" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Edoardo Salladini", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4WQO", "PDB:5N4W" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00888", "PF10557", "PF26557" ]
[ "Cullin alpha solenoid domain", "Cullin protein neddylation domain", "Cullin alpha+beta domain" ]
3
[ "CUL2" ]
[ 117, 625, 645 ]
[ 134, 634, 660 ]
[ "D", "D", "D" ]
6
DP02754
Q9S7B5
UPI0000048A1F
Threonine synthase 1, chloroplastic
Arabidopsis thaliana
3,702
526
0.032319
[]
[ "Eukaryota", "Viridiplantae", "Streptophyta", "Embryophyta", "Tracheophyta", "Spermatophyta", "Magnoliopsida", "eudicotyledons", "Gunneridae", "Pentapetalae", "rosids", "malvids", "Brassicales", "Brassicaceae", "Camelineae", "Arabidopsis" ]
2021_06
2020-04-14T11:52:14.482Z
fquaglia
UniRef100_Q9S7B5
UniRef90_Q9S7B5
UniRef50_Q9S7B5
MASSCLFNASVSSLNPKQDPIRRHRSTSLLRHRPVVISCTADGNNIKAPIETAVKPPHRTEDNIRDEARRNRSNAVNPFSAKYVPFNAAPGSTESYSLDEIVYRSRSGGLLDVEHDMEALKRFDGAYWRDLFDSRVGKSTWPYGSGVWSKKEWVLPEIDDDDIVSAFEGNSNLFWAERFGKQFLGMNDLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAGIPSIVFLPANKISMAQLVQPIANGAFVLSIDTDFDGCMKLIREITAELPIYLANSLNSLRLEGQKTAAIEILQ...
1
[ "DP02754r001" ]
[ 347 ]
[ 363 ]
[ 17 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "11344332" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1E5X" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.40.50.1100", "PF00291" ]
[ "G3DSA:3.40.50.1100", "Pyridoxal-phosphate dependent enzyme" ]
2
[ "At4g29840", "F27B13.80", "MTO2", "TS1" ]
[ 347 ]
[ 363 ]
[ "D" ]
6
DP02756
P21447
UPI000016CFAF
ATP-dependent translocase ABCB1
Mus musculus
10,090
1,276
0.047022
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-14T13:10:12.292Z
fquaglia
UniRef100_P21447
UniRef90_P21447
UniRef50_P21447
MELEEDLKGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISK...
4
[ "DP02756r001", "DP02756r002", "DP02756r003", "DP02756r004" ]
[ 627, 627, 627, 627 ]
[ 686, 686, 683, 683 ]
[ 60, 60, 57, 57 ]
[ "disorder", "flexible linker", "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "27864369", "27864369", "23901103", "23901103" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4KSB", "PDB:4KSC", "PDB:4KSD", "PDB:5KPI" ]
[ "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.20.1560.10", "G3DSA:1.20.1560.10", "PF00005", "PF00005", "PF00664", "PF00664" ]
[ "ABC transporter type 1, transmembrane domain", "ABC transporter type 1, transmembrane domain", "ABC transporter", "ABC transporter", "ABC transporter transmembrane region", "ABC transporter transmembrane region" ]
6
[ "Abcb1a", "Abcb4", "Mdr1a", "Mdr3", "Pgy-3", "Pgy3" ]
[ 627 ]
[ 686 ]
[ "D" ]
5
DP02757
Q9GZU1
UPI00000377A2
Mucolipin-1
Homo sapiens
9,606
580
0.212069
[ "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_06
2020-04-14T13:39:59.648Z
fquaglia
UniRef100_Q9GZU1
UniRef90_Q9GZU1
UniRef50_Q9GZU1
MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSL...
7
[ "DP02757r001", "DP02757r002", "DP02757r003", "DP02757r004", "DP02757r005", "DP02757r006", "DP02757r007" ]
[ 1, 206, 527, 206, 573, 564, 48 ]
[ 59, 215, 580, 215, 578, 568, 59 ]
[ 59, 10, 54, 10, 6, 5, 12 ]
[ "disorder", "disorder", "disorder", "flexible linker", "localization", "palmitoylation display site", "disorder to order" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000033", "GO:0051179", "IDPO:0000044", "IDPO:0000011" ]
[ "Structural state", "Structural state", "Structural state", "Disorder function", "Biological process", "Disorder function", "Structural transition" ]
[ "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006208", "ECO:0007719", "ECO:0005801", "ECO:0006208" ]
[ "29019983", "29019983", "29019983", "29019983", "16497227", "16497227", "29019983" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5WJ5", "PDB:5WJ9" ]
[ "pfam", "pfam" ]
[ "PF08016", "PF21381" ]
[ "Polycystin cation channel", "Mucolipin, extracytosolic domain" ]
2
[ "MCOLN1", "ML4", "MSTP080", "TRPML1" ]
[ 1, 48, 206, 527 ]
[ 47, 59, 215, 580 ]
[ "D", "T", "D", "D" ]
9
DP02758
Q13563
UPI0000131B69
Polycystin-2
Homo sapiens
9,606
968
0.028926
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-14T13:52:17.941Z
fquaglia
UniRef100_Q13563
UniRef90_Q13563
UniRef50_Q13563
MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIRQAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRPGSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPR...
2
[ "DP02758r001", "DP02758r002" ]
[ 198, 494 ]
[ 215, 503 ]
[ 18, 10 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006224", "ECO:0006224" ]
[ "27768895", "27768895" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5T4D" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.20.120.350", "PF08016", "PF18109", "PF20519" ]
[ "Voltage-gated potassium channels. Chain C", "Polycystin cation channel", "Ferredoxin I 4Fe-4S cluster domain", "Polycystin domain" ]
4
[ "PKD2", "TRPP2" ]
[ 198, 494 ]
[ 215, 503 ]
[ "D", "D" ]
4
DP02759
Q14181
UPI000012977B
DNA polymerase alpha subunit B
Homo sapiens
9,606
598
0.26087
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-04-14T20:58:17.251Z
lchemes
UniRef100_Q14181
UniRef90_Q14181
UniRef50_Q14181
MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSEILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAFTPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQVVIMEGINTTGRKLVATKLY...
2
[ "DP02759r001", "DP02759r002" ]
[ 1, 79 ]
[ 156, 156 ]
[ 156, 78 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "25847248", "25847248" ]
[ "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:4Y97" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.8.530", "PF04042", "PF08418", "PF22062" ]
[ "G3DSA:1.10.8.530", "DNA polymerase alpha/epsilon subunit B", "DNA polymerase alpha subunit B N-terminal", "DNA polymerase alpha subunit B, OB domain" ]
4
[ "POLA2" ]
[ 1 ]
[ 156 ]
[ "D" ]
9
DP02760
P76216
UPI000003EB36
N-succinylarginine dihydrolase
Escherichia coli (strain K12)
83,333
447
0.035794
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2021_06
2020-04-15T05:03:56.200Z
lchemes
UniRef100_C4ZZA1
UniRef90_Q32G87
UniRef50_Q32G87
MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLV...
3
[ "DP02760r001", "DP02760r002", "DP02760r004" ]
[ 19, 19, 19 ]
[ 34, 34, 34 ]
[ 16, 16, 16 ]
[ "disorder", "disorder to order", "order" ]
[ "IDPO:0000002", "IDPO:0000011", "IDPO:0000006" ]
[ "Structural state", "Structural transition", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005670" ]
[ "15703173", "15703173", "15703173" ]
[ "pmid", "pmid", "pmid" ]
[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:1YNF", "PDB:1YNH", "PDB:1YNI" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.75.10.20", "PF04996" ]
[ "Succinylarginine dihydrolase", "Succinylarginine dihydrolase" ]
2
[ "JW1734", "astB", "b1745", "ydjT" ]
[ 19 ]
[ 34 ]
[ "T" ]
8
DP02761
P25299
UPI0000052DDF
mRNA 3'-end-processing protein RNA15
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
296
0.358108
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-15T06:25:05.610Z
lchemes
UniRef100_P25299
UniRef90_P25299
UniRef50_P25299
MNRQSGVNAGVQNNPPSRVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYSSNSDISGVSQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPELPSGIDVNINMTTPAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLSFVTAELLLTNGICKVDDLIPLASRPQEEASATNNNSVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDDERMAIWDLKQKALRGEFGAF
5
[ "DP02761r001", "DP02761r002", "DP02761r003", "DP02761r004", "DP02761r005" ]
[ 127, 127, 127, 127, 127 ]
[ 232, 232, 232, 232, 232 ]
[ 106, 106, 106, 106, 106 ]
[ "disorder", "disorder", "disorder to order", "protein binding", "molecular adaptor activity" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000011", "GO:0005515", "GO:0060090" ]
[ "Structural state", "Structural state", "Structural transition", "Molecular function", "Molecular function" ]
[ "ECO:0006165", "ECO:0006204", "ECO:0006165", "ECO:0006165", "ECO:0006165" ]
[ "21481776", "21481776", "21481776", "21481776", "21481776" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:2L9B" ]
[ "gene3D", "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.30.70.330", "G3DSA:1.10.20.70", "PF00076", "PF14304" ]
[ "G3DSA:3.30.70.330", "G3DSA:1.10.20.70", "RNA recognition motif", "Transcription termination and cleavage factor C-terminal" ]
4
[ "RNA15", "YGL044C" ]
[ 127 ]
[ 232 ]
[ "T" ]
9
DP02763
Q9VI75
UPI000007F038
Phosphatidylinositol-binding clathrin assembly protein LAP
Drosophila melanogaster
7,227
468
0.038462
[]
[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]
2020_12
2020-04-15T09:14:17.201Z
fquaglia
UniRef100_Q9VI75
UniRef90_Q9VI75
UniRef50_Q9VI75
MTMAGQTINDRLLAARHSLAGQGLAKSVCKATTEECIGPKKKHLDYLVHCTNEPNVSIPHLANLLIERSQNANWVVVYKSLITTHHLMAYGNERFMQYLASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLRSMNAEKLLKTLPVLQAQLDALLEFDCQSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAENVGIDKGDIPDLTKAPSSLLDALEQHLATLEGRKVSAANTPTQSSSSAFGT...
1
[ "DP02763r001" ]
[ 4 ]
[ 21 ]
[ 18 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "11239400" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1HX8" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:1.25.40.90", "G3DSA:1.20.58.150", "PF07651" ]
[ "G3DSA:1.25.40.90", "G3DSA:1.20.58.150", "ANTH domain" ]
3
[ "CG2520", "lap" ]
[ 4 ]
[ 21 ]
[ "D" ]
3
DP02764
Q13162
UPI00001314E8
Peroxiredoxin-4
Homo sapiens
9,606
271
0.276753
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-15T10:52:12.261Z
fquaglia
UniRef100_Q13162
UniRef90_Q13162
UniRef50_Q13162
MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
3
[ "DP02764r001", "DP02764r002", "DP02764r003" ]
[ 1, 1, 1 ]
[ 75, 75, 271 ]
[ 75, 75, 271 ]
[ "molecular adaptor activity", "disorder", "molecular sequestering activity" ]
[ "GO:0060090", "IDPO:0000002", "GO:0140313" ]
[ "Molecular function", "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005801" ]
[ "21916849", "21916849", "21916849" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3TKP", "PDB:3TKQ", "PDB:3TKR", "PDB:3TKS" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.40.30.10", "PF00578", "PF10417" ]
[ "Glutaredoxin", "AhpC/TSA family", "C-terminal domain of 1-Cys peroxiredoxin" ]
3
[ "PRDX4" ]
[ 1, 76 ]
[ 75, 271 ]
[ "D", "F" ]
2
DP02765
Q14118
UPI000013EDAE
Dystroglycan
Homo sapiens
9,606
895
0.031285
[ "Extracellular matrix proteins", "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-04-15T11:44:05.074Z
fquaglia
UniRef100_Q14118
UniRef90_Q14118
UniRef50_Q14118
MRMSVGLSLLLPLSGRTFLLLLSVVMAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHEAVPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGLPLDTDKGVHYISVSATRLGANGSHIPQTSSVFSIEVYPEDHSELQSVRTASPDPGEVVSSACAADEPVTVLTVILDADLTKMTPKQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLNQNSVPDIHGVEAPAREGAMSAQLGYPVVGWHIANKKPPLPKRVRRQIHATPTP...
5
[ "DP02765r001", "DP02765r002", "DP02765r003", "DP02765r004", "DP02765r005" ]
[ 163, 163, 305, 163, 163 ]
[ 179, 179, 315, 179, 179 ]
[ 17, 17, 11, 17, 17 ]
[ "disorder", "flexible linker", "disorder", "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002", "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function", "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006210", "ECO:0006210" ]
[ "28781947", "28781947", "28781947", "28781947", "28781947" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5LLK" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "G3DSA:3.30.70.1040", "PF05345", "PF05454", "PF18424" ]
[ "Immunoglobulins", "Immunoglobulins", "Dystroglycan, domain 2", "Putative Ig domain", "Dystroglycan (Dystrophin-associated glycoprotein 1)", "Alpha-Dystroglycan N-terminal domain 2" ]
6
[ "DAG1" ]
[ 163, 305 ]
[ 179, 315 ]
[ "D", "D" ]
5
DP02767
P15442
UPI000012B2E6
eIF-2-alpha kinase GCN2
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
1,659
0.105485
[ "RNA-binding proteins" ]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2023_12
2020-04-15T13:25:38.939Z
fquaglia
UniRef100_P15442
UniRef90_P15442
UniRef50_P15442
MSLSHLTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKSSWDKQPQIIFEITLRSVDKEPVESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSFTQEKLDEFQNVVNTQSLEDDRLQRIKETKEQLEKEEREKQQETIKKRSDEQRRIDEIVQRELEKRQDDDDDLLFNRTTQLDLQPPSEWVASGEAIVFSKTIKAKLPNNSMFKFKAVVNPKPIKLTSDIFSFSKQFLVKPYIPPESPLADFLMSSEMMENFYYLLSEIELDNSYFNTSNGKKEIANLEKELETVLKAKHDN...
6
[ "DP02767r001", "DP02767r004", "DP02767r005", "DP02767r006", "DP02767r007", "DP02767r008" ]
[ 921, 861, 861, 1519, 1519, 665 ]
[ 951, 882, 882, 1537, 1537, 767 ]
[ 31, 22, 22, 19, 19, 103 ]
[ "disorder", "disorder", "phosphorylation display site", "disorder", "flexible linker", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000045", "IDPO:0000002", "IDPO:0000033", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Disorder function", "Structural state", "Disorder function", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0007687", "ECO:0006220", "ECO:0006220", "ECO:0001191" ]
[ "15964839", "15964839", "15964839", "24719324", "24719324", "15964839" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:1ZXE", "PDB:1ZY4", "PDB:1ZY5", "PDB:1ZYC", "PDB:1ZYD", "PDB:4OTM" ]
[ "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:3.10.110.10", "G3DSA:3.40.50.800", "PF00069", "PF00069", "PF00069", "PF05773", "PF12745", "PF13393" ]
[ "Ubiquitin Conjugating Enzyme", "Anticodon-binding domain", "Protein kinase domain", "Protein kinase domain", "Protein kinase domain", "RWD domain", "Anticodon binding domain of tRNAs", "Histidyl-tRNA synthetase" ]
8
[ "AAS1", "GCN2", "YDR283C" ]
[ 665, 861, 921, 1519 ]
[ 767, 882, 951, 1537 ]
[ "D", "D", "D", "D" ]
9
DP02768
P09950
UPI000012C441
5-aminolevulinate synthase, mitochondrial
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
548
0.120438
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-15T13:58:56.799Z
fquaglia
UniRef100_P09950
UniRef90_P09950
UniRef50_P09950
MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAAAANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGG...
7
[ "DP02768r001", "DP02768r002", "DP02768r003", "DP02768r004", "DP02768r005", "DP02768r006", "DP02768r007" ]
[ 58, 83, 83, 147, 147, 538, 538 ]
[ 71, 113, 113, 156, 156, 548, 548 ]
[ 14, 31, 31, 10, 10, 11, 11 ]
[ "disorder", "disorder", "disorder to order", "disorder to order", "disorder", "disorder", "disorder to order" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000011", "IDPO:0000011", "IDPO:0000002", "IDPO:0000002", "IDPO:0000011" ]
[ "Structural state", "Structural state", "Structural transition", "Structural transition", "Structural state", "Structural state", "Structural transition" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "29551290", "29551290", "29551290", "29551290", "29551290", "29551290", "29551290" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5TXR", "PDB:5TXT" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:3.40.640.10", "G3DSA:3.90.1150.10", "PF00155" ]
[ "Type I PLP-dependent aspartate aminotransferase-like (Major domain)", "Aspartate Aminotransferase, domain 1", "Aminotransferase class I and II" ]
3
[ "CYD1", "HEM1", "YD9934.16", "YDR232W" ]
[ 58, 83, 147, 538 ]
[ 71, 113, 156, 548 ]
[ "D", "T", "T", "T" ]
4
DP02769
P06782
UPI0000052F22
Carbon catabolite-derepressing protein kinase
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
633
0.028436
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-15T18:01:35.525Z
lchemes
UniRef100_P06782
UniRef90_P06782
UniRef50_P06782
MSSNNNTNTAPANANSSHHHHHHHHHHHHHGHGGSNSTLNNPKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLK...
3
[ "DP02769r001", "DP02769r002", "DP02769r003" ]
[ 200, 197, 197 ]
[ 214, 212, 212 ]
[ 15, 16, 16 ]
[ "disorder", "disorder", "molecular function activator activity" ]
[ "IDPO:0000002", "IDPO:0000002", "GO:0140677" ]
[ "Structural state", "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005670" ]
[ "16236260", "19474788", "20823513" ]
[ "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:3DAE", "PDB:3HYH", "PDB:3MN3" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00069", "PF08587", "PF16579" ]
[ "Protein kinase domain", "Ubiquitin associated domain (UBA)", "Adenylate sensor of SNF1-like protein kinase" ]
3
[ "CAT1", "CCR1", "D8035.20", "GLC2", "PAS14", "SNF1", "YDR477W" ]
[ 197 ]
[ 214 ]
[ "D" ]
7
DP02770
P01127
UPI000004110E
Platelet-derived growth factor subunit B
Homo sapiens
9,606
241
0.058091
[ "Cancer-related proteins", "Extracellular matrix proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-15T19:21:15.915Z
lchemes
UniRef100_P01127
UniRef90_P01127
UniRef50_P01127
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
3
[ "DP02770r001", "DP02770r002", "DP02770r003" ]
[ 106, 106, 106 ]
[ 119, 119, 119 ]
[ 14, 14, 14 ]
[ "disorder", "disorder to order", "platelet-derived growth factor receptor binding" ]
[ "IDPO:0000002", "IDPO:0000011", "GO:0005161" ]
[ "Structural state", "Structural transition", "Molecular function" ]
[ "ECO:0006220", "ECO:0005670", "ECO:0005670" ]
[ "1396586", "20534510", "20534510" ]
[ "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:1PDG", "PDB:3MJG" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:2.10.90.10", "PF00341", "PF04692" ]
[ "Cystine-knot cytokines", "PDGF/VEGF domain", "Platelet-derived growth factor, N terminal region" ]
3
[ "PDGF2", "PDGFB", "SIS" ]
[ 106 ]
[ 119 ]
[ "T" ]
2
DP02772
P0DTC2
UPI00131F240A
Spike glycoprotein
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
2,697,049
1,273
0.28044
[ "Viral proteins" ]
[ "Viruses", "Riboviria", "Orthornavirae", "Pisuviricota", "Pisoniviricetes", "Nidovirales", "Cornidovirineae", "Coronaviridae", "Orthocoronavirinae", "Betacoronavirus", "Sarbecovirus" ]
2020_06
2020-04-15T21:05:10.000Z
ahatos
UniRef100_P0DTC2
UniRef90_P0DTC2
UniRef50_P0DTC2
MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRV...
37
[ "DP02772r001", "DP02772r002", "DP02772r003", "DP02772r004", "DP02772r005", "DP02772r006", "DP02772r007", "DP02772r008", "DP02772r009", "DP02772r010", "DP02772r011", "DP02772r012", "DP02772r013", "DP02772r014", "DP02772r015", "DP02772r016", "DP02772r017", "DP02772r018", "DP02772r0...
[ 70, 144, 173, 246, 469, 621, 677, 828, 1148, 1, 67, 142, 246, 455, 621, 673, 829, 1147, 319, 527, 319, 527, 319, 319, 519, 680, 681, 437, 681, 16, 330, 73, 148, 1157, 1172, 1194, 319 ]
[ 79, 164, 185, 262, 488, 640, 687, 853, 1273, 26, 80, 154, 262, 490, 637, 686, 852, 1208, 332, 541, 332, 541, 541, 335, 541, 685, 686, 508, 686, 21, 335, 78, 153, 1162, 1177, 1198, 541 ]
[ 10, 21, 13, 17, 20, 20, 11, 26, 126, 26, 14, 13, 17, 36, 17, 14, 24, 62, 14, 15, 14, 15, 223, 17, 23, 6, 6, 72, 6, 6, 6, 6, 6, 6, 6, 5, 223 ]
[ "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "disorder", "protein...
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000...
[ "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Structu...
[ "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:0006224", "ECO:00062...
[ "32155444", "32155444", "32155444", "32155444", "32155444", "32155444", "32155444", "32155444", "32155444", "32075877", "32075877", "32075877", "32075877", "32075877", "32075877", "32075877", "32075877", "32075877", "32225176", "32225176", "32245784", "32245784", "3213218...
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid"...
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federic...
[ "EMDB:30039", "EMDB:30046", "PDB:6M0J", "PDB:6M17", "PDB:6VSB", "PDB:6VXX", "PDB:6VYB", "PDB:6W41" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.20.5.790", "PF01601", "PF09408", "PF16451", "PF19209" ]
[ "Single helix bin", "Coronavirus spike glycoprotein S2", "Betacoronavirus spike glycoprotein S1, receptor binding", "Betacoronavirus-like spike glycoprotein S1, N-terminal", "Coronavirus spike glycoprotein S1, C-terminal" ]
5
[ "2", "S" ]
[ 1, 67, 142, 173, 246, 319, 621, 673, 828, 1147 ]
[ 26, 80, 164, 185, 262, 541, 640, 687, 853, 1273 ]
[ "D", "D", "D", "D", "D", "T", "D", "D", "D", "D" ]
5
DP02782
Q9NPI8
UPI000012A4CA
Fanconi anemia group F protein
Homo sapiens
9,606
374
0.096257
[ "Cancer-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-16T16:47:46.556Z
fquaglia
UniRef100_Q9NPI8
UniRef90_Q9NPI8
UniRef50_Q9NPI8
MESLLQHLDRFSELLAVSSTTYVSTWDPATVRRALQWARYLRHIHRRFGRHGPIRTALERRLHNQWRQEGGFGRGPVPGLANFQALGHCDVLLSLRLLENRALGDAARYHLVQQLFPGPGVRDADEETLQESLARLARRRSAVHMLRFNGYRENPNLQEDSLMKTQAELLLERLQEVGKAEAERPARFLSSLWERLPQNNFLKVIAVALLQPPLSRRPQEELEPGIHKSPGEGSQVLVHWLLGNSEVFAAFCRALPAGLLTLVTSRHPALSPVYLGLLTDWGQRLHYDLQKGIWVGTESQDVPWEELHNRFQSLCQAPPP...
2
[ "DP02782r001", "DP02782r002" ]
[ 211, 177 ]
[ 234, 188 ]
[ 24, 12 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "17082180", "17082180" ]
[ "pmid", "pmid" ]
[ "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:2IQC" ]
[ "gene3D", "pfam" ]
[ "G3DSA:1.25.40.490", "PF11107" ]
[ "G3DSA:1.25.40.490", "Fanconi anemia group F protein (FANCF)" ]
2
[ "FANCF" ]
[ 177, 211 ]
[ 188, 234 ]
[ "D", "D" ]
2
DP02783
P49189
UPI000016A525
4-trimethylaminobutyraldehyde dehydrogenase
Homo sapiens
9,606
494
0.048583
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-16T17:20:42.844Z
fquaglia
UniRef100_P49189
UniRef90_P49189
UniRef50_P49189
MSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDP...
2
[ "DP02783r001", "DP02783r002" ]
[ 232, 232 ]
[ 255, 255 ]
[ 24, 24 ]
[ "disorder", "small molecule binding" ]
[ "IDPO:0000002", "GO:0036094" ]
[ "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "30914451", "30914451" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:6QAK", "PDB:6QAO", "PDB:6QAP" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:3.40.605.10", "G3DSA:3.40.309.10", "PF00171" ]
[ "Aldehyde Dehydrogenase; Chain A, domain 1", "Aldehyde Dehydrogenase; Chain A, domain 2", "Aldehyde dehydrogenase family" ]
3
[ "ALDH4", "ALDH7", "ALDH9", "ALDH9A1" ]
[ 232 ]
[ 255 ]
[ "D" ]
5
DP02784
P16892
UPI000012AD91
Mitogen-activated protein kinase FUS3
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
353
0.045326
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-16T17:47:46.360Z
fquaglia
UniRef100_P16892
UniRef90_P16892
UniRef50_P16892
MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPE...
1
[ "DP02784r001" ]
[ 164 ]
[ 179 ]
[ 16 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "16364919" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:2B9F", "PDB:2B9H", "PDB:2B9I", "PDB:2B9J" ]
[ "pfam" ]
[ "PF00069" ]
[ "Protein kinase domain" ]
1
[ "DAC2", "FUS3", "YBL016W", "YBL03.21", "YBL0303" ]
[ 164 ]
[ 179 ]
[ "D" ]
3
DP02785
P16278
UPI0000E9BBE7
Beta-galactosidase
Homo sapiens
9,606
677
0.064993
[ "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-16T18:10:18.978Z
fquaglia
UniRef100_P16278
UniRef90_P16278
UniRef50_P16278
MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGA...
3
[ "DP02785r001", "DP02785r002", "DP02785r003" ]
[ 531, 531, 648 ]
[ 544, 544, 677 ]
[ 14, 14, 30 ]
[ "disorder", "flexible linker", "disorder" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "22128166", "22128166", "22128166" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3THC", "PDB:3THD" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.120.260", "PF01301", "PF21317", "PF21467" ]
[ "Galactose-binding domain-like", "Glycosyl hydrolases family 35", "Beta-galactosidase, first all-beta domain", "Beta-galactosidase, galactose-binding domain" ]
4
[ "ELNR1", "GLB1" ]
[ 531, 648 ]
[ 544, 677 ]
[ "D", "D" ]
3
DP02786
Q9Y823
UPI000006C25C
Homocitrate synthase, mitochondrial
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
284,812
418
0.095694
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Taphrinomycotina", "Schizosaccharomycetes", "Schizosaccharomycetales", "Schizosaccharomycetaceae", "Schizosaccharomyces" ]
2021_06
2020-04-16T18:39:28.478Z
fquaglia
UniRef100_Q9Y823
UniRef90_Q9Y823
UniRef50_P48570
MSVSEANGTETIKPPMNGNPYGPNPSDFLSRVNNFSIIESTLREGEQFANAFFDTEKKIQIAKALDNFGVDYIELTSPVASEQSRQDCEAICKLGLKCKILTHIRCHMDDARVAVETGVDGVDVVIGTSQYLRKYSHGKDMTYIIDSATEVINFVKSKGIEVRFSSEDSFRSDLVDLLSLYKAVDKIGVNRVGIADTVGCATPRQVYDLIRTLRGVVSCDIECHFHNDTGMAIANAYCALEAGATHIDTSILGIGERNGITPLGALLARMYVTDREYITHKYKLNQLRELENLVADAVEVQIPFNNYITGMCAFTHKAGI...
6
[ "DP02786r001", "DP02786r002", "DP02786r003", "DP02786r004", "DP02786r005", "DP02786r006" ]
[ 406, 129, 129, 320, 320, 320 ]
[ 418, 141, 141, 333, 333, 333 ]
[ 13, 13, 13, 14, 14, 14 ]
[ "disorder", "disorder", "disorder to order", "disorder", "disorder to order", "entropic chain" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000011", "IDPO:0000002", "IDPO:0000011", "IDPO:0000030" ]
[ "Structural state", "Structural state", "Structural transition", "Structural state", "Structural transition", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "19776021", "19776021", "19776021", "19776021", "19776021", "19776021" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3IVS", "PDB:3IVT", "PDB:3IVU" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.20.20.70", "PF00682", "PF22617" ]
[ "Aldolase class I", "HMGL-like", "Homocitrate synthase post-HMGL domain-like" ]
3
[ "SPBC1105.02c", "lys4" ]
[ 129, 320, 406 ]
[ 141, 333, 418 ]
[ "T", "T", "D" ]
8
DP02787
P45523
UPI000012A826
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA
Escherichia coli (strain K12)
83,333
270
0.118519
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2021_06
2020-04-16T22:28:46.104Z
fquaglia
UniRef100_P45523
UniRef90_P45523
UniRef50_P45523
MKSLFKVTLLATTMAVALHAPITFAAEAAKPATAADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLVIPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK
4
[ "DP02787r001", "DP02787r002", "DP02787r003", "DP02787r004" ]
[ 26, 15, 253, 253 ]
[ 39, 114, 270, 270 ]
[ 14, 100, 18, 18 ]
[ "disorder", "protein folding chaperone", "disorder", "disorder to order" ]
[ "IDPO:0000002", "GO:0044183", "IDPO:0000002", "IDPO:0000011" ]
[ "Structural state", "Molecular function", "Structural state", "Structural transition" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "14672666", "14672666", "14672666", "14672666" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1Q6H", "PDB:1Q6I", "PDB:1Q6U" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:1.10.287.460", "PF00254", "PF01346" ]
[ "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain", "FKBP-type peptidyl-prolyl cis-trans isomerase", "Domain amino terminal to FKBP-type peptidyl-prolyl isomerase" ]
3
[ "JW3309", "b3347", "fkpA", "yzzS" ]
[ 15, 26, 40, 253 ]
[ 25, 39, 114, 270 ]
[ "F", "D", "F", "T" ]
3
DP02789
Q62902
UPI00000E5B96
Protein ERGIC-53
Rattus norvegicus
10,116
517
0.03675
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]
2020_12
2020-04-17T09:37:14.209Z
fquaglia
UniRef100_Q62902
UniRef90_Q62902
UniRef50_Q62902
MAVSRRRGPQAGAQSFFCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQGLDGPVFGSADMWNGVGIFFDSFDNDGKKNNPAIVVVGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHP...
1
[ "DP02789r001" ]
[ 31 ]
[ 49 ]
[ 19 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "11850423" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1GV9" ]
[ "pfam" ]
[ "PF03388" ]
[ "Legume-like lectin family" ]
1
[ "Ergic53", "Lman1" ]
[ 31 ]
[ 49 ]
[ "D" ]
9
DP02790
Q8BTI9
UPI00000EAB6E
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Mus musculus
10,090
1,064
0.069549
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-17T09:44:41.065Z
fquaglia
UniRef100_Q8BTI9
UniRef90_P42338
UniRef50_P42338
MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRVISHI...
5
[ "DP02790r001", "DP02790r002", "DP02790r003", "DP02790r004", "DP02790r005" ]
[ 1, 299, 402, 514, 299 ]
[ 12, 319, 431, 524, 319 ]
[ 12, 21, 30, 11, 21 ]
[ "disorder", "disorder", "disorder", "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Structural state", "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "21362552", "21362552", "21362552", "21362552", "21362552" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2Y3A" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.40.150", "G3DSA:1.10.1070.11", "G3DSA:1.25.40.70", "PF00454", "PF00613", "PF00792", "PF00794", "PF02192" ]
[ "C2 domain", "Phosphatidylinositol 3-/4-kinase, catalytic domain", "G3DSA:1.25.40.70", "Phosphatidylinositol 3- and 4-kinase", "Phosphoinositide 3-kinase family, accessory domain (PIK domain)", "Phosphoinositide 3-kinase C2", "PI3-kinase family, ras-binding domain", "PI3-kinase family, p85-binding dom...
8
[ "Pik3cb" ]
[ 1, 299, 402, 514 ]
[ 12, 319, 431, 524 ]
[ "D", "D", "D", "D" ]
9
DP02791
O08908
UPI000024DFD5
Phosphatidylinositol 3-kinase regulatory subunit beta
Mus musculus
10,090
722
0.069252
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2020_12
2020-04-17T10:14:01.780Z
fquaglia
UniRef100_O08908
UniRef90_O08908
UniRef50_O00459
MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGSSESGHILPDLAEQFSPPDPAPPILVKLVEAIEQAELDSECYSKPELPATRTDWSLSDLEQWDRTALYDAVKGFLLALPAAVVTPEAAAEAYRALREVAGPVGLVLEPPTLPLHQALTLRFLLQHLGRVARRAPSPDTAVHALASAFGPLLLRIPPSGGEGDGSEPVPDFPVLLLERLVQEHVEEQDAAPPALPPKPSKAKPAPTALANGGSPPSLQ...
5
[ "DP02791r001", "DP02791r002", "DP02791r003", "DP02791r004", "DP02791r005" ]
[ 423, 576, 423, 576, 576 ]
[ 440, 607, 440, 607, 607 ]
[ 18, 32, 18, 32, 32 ]
[ "disorder", "disorder", "flexible linker", "flexible linker", "phosphorylation display site" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033", "IDPO:0000033", "IDPO:0000045" ]
[ "Structural state", "Structural state", "Disorder function", "Disorder function", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "21362552", "21362552", "21362552", "21362552", "21362552" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2Y3A" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.555.10", "G3DSA:3.30.505.10", "G3DSA:3.30.505.10", "PF00017", "PF00017", "PF00620", "PF16454" ]
[ "Rho GTPase activation protein", "SH2 domain", "SH2 domain", "SH2 domain", "SH2 domain", "RhoGAP domain", "Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain" ]
7
[ "Pik3r2" ]
[ 423, 576 ]
[ 440, 607 ]
[ "D", "D" ]
3
DP02792
P42337
UPI0000027AB6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Mus musculus
10,090
1,068
0.035581
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_12
2020-04-17T11:27:28.950Z
fquaglia
UniRef100_P42337
UniRef90_P42336
UniRef50_P42336
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQLLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNG...
4
[ "DP02792r001", "DP02792r002", "DP02792r003", "DP02792r004" ]
[ 310, 310, 501, 501 ]
[ 322, 322, 525, 525 ]
[ 13, 13, 25, 25 ]
[ "disorder", "flexible linker", "flexible linker", "disorder" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000033", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Disorder function", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "22120714", "22120714", "22120714", "22120714" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4A55" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.1070.11", "PF00454", "PF00613", "PF00792", "PF00794", "PF02192" ]
[ "Phosphatidylinositol 3-/4-kinase, catalytic domain", "Phosphatidylinositol 3- and 4-kinase", "Phosphoinositide 3-kinase family, accessory domain (PIK domain)", "Phosphoinositide 3-kinase C2", "PI3-kinase family, ras-binding domain", "PI3-kinase family, p85-binding domain" ]
6
[ "Pik3ca" ]
[ 310, 501 ]
[ 322, 525 ]
[ "D", "D" ]
8
DP02793
Q63716
UPI00001314E2
Peroxiredoxin-1
Rattus norvegicus
10,116
199
0.120603
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Rattus" ]
2020_12
2020-04-17T14:58:24.048Z
fquaglia
UniRef100_Q63716
UniRef90_Q06830
UniRef50_Q06830
MSSGNAKIGHPAPSFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEILRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVNKSKEYFSKQK
1
[ "DP02793r001" ]
[ 176 ]
[ 199 ]
[ 24 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "10535922" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1QQ2" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.40.30.10", "PF00578", "PF10417" ]
[ "Glutaredoxin", "AhpC/TSA family", "C-terminal domain of 1-Cys peroxiredoxin" ]
3
[ "Prdx1", "Tdpx2" ]
[ 176 ]
[ 199 ]
[ "D" ]
5
DP02794
P22234
UPI000042AB67
Multifunctional protein ADE2
Homo sapiens
9,606
425
0.077647
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-17T15:35:10.416Z
fquaglia
UniRef100_P22234
UniRef90_P22234
UniRef50_P22234
MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDG...
2
[ "DP02794r001", "DP02794r002" ]
[ 37, 221 ]
[ 51, 238 ]
[ 15, 18 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "17224163", "17224163" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2H31" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.40.50.7700", "PF00731", "PF01259" ]
[ "PurE domain", "AIR carboxylase", "SAICAR synthetase" ]
3
[ "ADE2", "AIRC", "PAICS", "PAIS" ]
[ 37, 221 ]
[ 51, 238 ]
[ "D", "D" ]
1
DP02795
Q9NV23
UPI0000047465
S-acyl fatty acid synthase thioesterase, medium chain
Homo sapiens
9,606
265
0.158491
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-04-17T15:54:22.701Z
fquaglia
UniRef100_Q9NV23
UniRef90_Q9NV23
UniRef50_P08635
MERGDQPKRTRNENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLRLPGRESRVEEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF
3
[ "DP02795r001", "DP02795r002", "DP02795r003" ]
[ 1, 59, 59 ]
[ 24, 76, 76 ]
[ 24, 18, 18 ]
[ "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "26663084", "26663084", "26663084" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4XJV" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.40.50.1820", "PF00975" ]
[ "G3DSA:3.40.50.1820", "Thioesterase domain" ]
2
[ "OLAH", "THEDC1" ]
[ 1, 59 ]
[ 24, 76 ]
[ "D", "D" ]
2
DP02796
Q56026
UPI00000D0143
Cell invasion protein SipD
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
99,287
343
0.122449
[ "Bacterial virulence-related proteins" ]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Salmonella" ]
2025_06
2020-04-17T22:21:00.948Z
fquaglia
UniRef100_Q56026
UniRef90_Q56026
UniRef50_Q56026
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQTLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLLPGKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNLPNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEENMKTTLQTLTQKYSNANSLYD...
3
[ "DP02796r001", "DP02796r002", "DP02796r003" ]
[ 111, 1, 1 ]
[ 131, 21, 21 ]
[ 21, 21, 21 ]
[ "disorder", "disorder", "flexible N-terminal tail" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000032" ]
[ "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "21031487", "21829362", "21829362" ]
[ "pmid", "pmid", "pmid" ]
[ "Victoria Nugnes", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:3NZZ" ]
[ "gene3D", "pfam" ]
[ "G3DSA:1.20.1710.10", "PF06511" ]
[ "IpaD-like", "Type III secretion systems tip complex components" ]
2
[ "STM2883", "sipD", "sspD" ]
[ 1, 111 ]
[ 21, 131 ]
[ "D", "D" ]
7
DP02797
P20061
UPI0000136AE1
Transcobalamin-1
Homo sapiens
9,606
433
0.083141
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-04-17T22:55:15.736Z
fquaglia
UniRef100_P20061
UniRef90_P20061
UniRef50_P20061
MRQSHQLPLVGLLLFSFIPSQLCEICEVSEENYIRLKPLLNTMIQSNYNRGTSAVNVVLSLKLVGIQIQTLMQKMIQQIKYNVKSRLSDVSSGELALIILALGVCRNAEENLIYDYHLIDKLENKFQAEIENMEAHNGTPLTNYYQLSLDVLALCLFNGNYSTAEVVNHFTPENKNYYFGSQFSVDTGAMAVLALTCVKKSLINGQIKADEGSLKNISIYTKSLVEKILSEKKENGLIGNTFSTGEAMQALFVSSDYYNENDWNCQQTLNTVLTEISQGAFSNPNAAAQVLPALMGKTFLDINKDSSCVSASGNFNISAD...
3
[ "DP02797r001", "DP02797r002", "DP02797r003" ]
[ 318, 318, 1 ]
[ 330, 330, 23 ]
[ 13, 13, 23 ]
[ "disorder", "flexible linker", "disorder" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Structural state" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "23846701", "23846701", "23846701" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Victoria Nugnes" ]
[ "PDB:4KKI", "PDB:4KKJ" ]
[ "pfam", "pfam" ]
[ "PF01122", "PF14478" ]
[ "Eukaryotic cobalamin-binding protein", "Domain of unknown function (DUF4430)" ]
2
[ "TC1", "TCN1" ]
[ 1, 318 ]
[ 23, 330 ]
[ "D", "D" ]
5
DP02799
P34257
UPI0000136AB1
Transposable element Tc3 transposase
Caenorhabditis elegans
6,239
329
0.097264
[]
[ "Eukaryota", "Metazoa", "Ecdysozoa", "Nematoda", "Chromadorea", "Rhabditida", "Rhabditina", "Rhabditomorpha", "Rhabditoidea", "Rhabditidae", "Peloderinae", "Caenorhabditis" ]
2021_06
2020-04-20T09:42:37.732Z
fquaglia
UniRef100_P34257
UniRef90_P34257
UniRef50_P34257
MPRGSALSDTERAQLDVMKLLNVSLHEMSRKISRSRHCIREYLKDPVSYGTSKRAPRRKALSVRDERNVIRAASNSCKTARDIRNELQLSASKRTILNVIKRSGVIVRQKLRPAPLLSADHKLKRLEFAKNNMGTNWSKVVFSDEKKFNLDGPDGCRYYWRDLRKEPMVFSRRNFGGGTVMVWGAFTEKKKLEIQFVSSKMNSTDYQNVLELELSKYLRHYSRKDFRFQQDNATIHVSNSTRDYFKLKKINLLDWPARSPDLNPIENLWGILVRIVYAQNKTYPTVASLKQGILDAWKSIPDNQLKSLVRSMEDRLIEII...
2
[ "DP02799r001", "DP02799r002" ]
[ 104, 104 ]
[ 135, 135 ]
[ 32, 32 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "15304566", "15304566" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1U78" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.10.10.10", "PF11427", "PF13358", "PF21517" ]
[ "Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain", "Tc3 transposase", "DDE superfamily endonuclease", "Transposable element Tc3 transposase, HTH" ]
4
[ "B0303.5", "tc3a" ]
[ 104 ]
[ 135 ]
[ "D" ]
5
DP02800
P63028
UPI00000233A4
Translationally-controlled tumor protein
Mus musculus
10,090
172
0.162791
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2020_12
2020-04-20T10:06:21.550Z
fquaglia
UniRef100_P63028
UniRef90_P63028
UniRef50_P63028
MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDDSLIGGNASAEGPEGEGTESTVVTGVDIVMNHHLQETSFTKEAYKKYIKDYMKSLKGKLEEQKPERVKPFMTGAAEQIKHILANFNNYQFFIGENMNPDGMVALLDYREDGVTPFMIFFKDGLEMEKC
2
[ "DP02800r001", "DP02800r002" ]
[ 39, 39 ]
[ 66, 66 ]
[ 28, 28 ]
[ "disorder", "molecular function regulator" ]
[ "IDPO:0000002", "GO:0098772" ]
[ "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0005670" ]
[ "29216544", "29216544" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5O9K" ]
[ "gene3D", "pfam" ]
[ "G3DSA:2.170.150.10", "PF00838" ]
[ "Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A", "Translationally controlled tumour protein" ]
2
[ "Tpt1", "Trt" ]
[ 39 ]
[ 66 ]
[ "D" ]
3
DP02801
P05452
UPI0000174155
Tetranectin
Homo sapiens
9,606
202
0.123762
[ "Extracellular matrix proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-20T10:28:00.100Z
fquaglia
UniRef100_P05452
UniRef90_P05452
UniRef50_P05452
MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV
3
[ "DP02801r001", "DP02801r002", "DP02801r003" ]
[ 22, 1, 1 ]
[ 46, 49, 49 ]
[ 25, 49, 49 ]
[ "disorder", "protein binding", "localization" ]
[ "IDPO:0000002", "GO:0005515", "GO:0051179" ]
[ "Structural state", "Molecular function", "Biological process" ]
[ "ECO:0006220", "ECO:0006218", "ECO:0006218" ]
[ "9256258", "9256258", "9256258" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1HTN" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.10.100.10", "PF00059" ]
[ "Mannose-Binding Protein A, subunit A", "Lectin C-type domain" ]
2
[ "CLEC3B", "TNA" ]
[ 1, 22, 47 ]
[ 21, 46, 49 ]
[ "F", "D", "F" ]
9
DP02802
Q921Z5
UPI00000289AE
Tumor necrosis factor alpha-induced protein 8
Mus musculus
10,090
198
0.060606
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-20T10:58:22.473Z
fquaglia
UniRef100_Q921Z5
UniRef90_Q921Z5
UniRef50_Q8WVP5
MLSEAEEPREVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHEIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI
3
[ "DP02802r001", "DP02802r002", "DP02802r003" ]
[ 1, 1, 1 ]
[ 12, 12, 12 ]
[ 12, 12, 12 ]
[ "disorder", "small molecule binding", "molecular sequestering activity" ]
[ "IDPO:0000002", "GO:0036094", "GO:0140313" ]
[ "Structural state", "Molecular function", "Molecular function" ]
[ "ECO:0006220", "ECO:0007184", "ECO:0007184" ]
[ "28740220", "28740220", "28740220" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5JXD" ]
[ "gene3D", "pfam" ]
[ "G3DSA:1.20.1440.160", "PF05527" ]
[ "G3DSA:1.20.1440.160", "Tumor necrosis factor alpha-induced protein 8-like" ]
2
[ "Tnfaip8" ]
[ 1 ]
[ 12 ]
[ "D" ]
2
DP02803
Q96Q11
UPI000013CD08
CCA tRNA nucleotidyltransferase 1, mitochondrial
Homo sapiens
9,606
434
0.145161
[ "NDDs-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-20T11:35:18.857Z
fquaglia
UniRef100_Q96Q11
UniRef90_Q96Q11
UniRef50_Q96Q11
MLRCLYHWHRPVLNRRWSRLCLPKQYLFTMKLQSPEFQSLFTEGLKSLTELFVKENHELRIAGGAVRDLLNGVKPQDIDFATTATPTQMKEMFQSAGIRMINNRGEKHGTITARLHEENFEITTLRIDVTTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFNGYEDLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDPETLEAIAENAKGLAGISGERIWVELKKILVGNHVNHLIHLIYDLDVAPYIGLPANASLEEFDKVSKNVDGFSPKPVTLLASLFKVQDDVTKLDLRLKIAKEEK...
2
[ "DP02803r001", "DP02803r002" ]
[ 128, 384 ]
[ 139, 434 ]
[ 12, 51 ]
[ "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "12729736", "12729736" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1OU5" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.30.460.10", "PF01743", "PF12627" ]
[ "Beta Polymerase, domain 2", "Poly A polymerase head domain", "Probable RNA and SrmB- binding site of polymerase A" ]
3
[ "CGI-47", "TRNT1" ]
[ 128, 384 ]
[ 139, 434 ]
[ "D", "D" ]
8
DP02804
P61587
UPI0000003FE9
Rho-related GTP-binding protein RhoE
Homo sapiens
9,606
244
0.077869
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-20T22:14:46.016Z
fquaglia
UniRef100_P61587
UniRef90_P61587
UniRef50_P61587
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM
3
[ "DP02804r001", "DP02804r002", "DP02804r003" ]
[ 1, 1, 1 ]
[ 19, 19, 19 ]
[ 19, 19, 19 ]
[ "disorder", "phosphorylation display site", "protein binding" ]
[ "IDPO:0000002", "IDPO:0000045", "GO:0005515" ]
[ "Structural state", "Disorder function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "18946488", "18946488", "18946488" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2V55" ]
[ "pfam" ]
[ "PF00071" ]
[ "Ras family" ]
1
[ "ARHE", "RHO8", "RHOE", "RND3" ]
[ 1 ]
[ 19 ]
[ "D" ]
7
DP02806
P0CY08
UPI000012EBF8
Mating-type protein ALPHA2
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
210
0.242857
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-21T20:04:48.848Z
lchemes
UniRef100_P0CY09
UniRef90_P0CY09
UniRef50_P0CY09
MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
11
[ "DP02806r001", "DP02806r002", "DP02806r003", "DP02806r004", "DP02806r005", "DP02806r006", "DP02806r007", "DP02806r008", "DP02806r009", "DP02806r010", "DP02806r011" ]
[ 103, 113, 103, 110, 110, 114, 190, 193, 193, 190, 190 ]
[ 132, 132, 132, 128, 128, 121, 210, 203, 203, 205, 205 ]
[ 30, 20, 30, 19, 19, 8, 21, 11, 11, 16, 16 ]
[ "disorder", "disorder to order", "flexible linker", "protein binding", "molecular function regulator", "molecular function regulator", "disorder", "molecular function regulator", "disorder to order", "disorder to order", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000011", "IDPO:0000033", "GO:0005515", "GO:0098772", "GO:0098772", "IDPO:0000002", "GO:0098772", "IDPO:0000011", "IDPO:0000011", "GO:0098772" ]
[ "Structural state", "Structural transition", "Disorder function", "Molecular function", "Molecular function", "Molecular function", "Structural state", "Molecular function", "Structural transition", "Structural transition", "Molecular function" ]
[ "ECO:0007691", "ECO:0005670", "ECO:0007691", "ECO:0001807", "ECO:0001807", "ECO:0005670", "ECO:0006220", "ECO:0006165", "ECO:0006165", "ECO:0005670", "ECO:0005670" ]
[ "3061876", "9490409", "3061876", "8422672", "8422672", "9490409", "1682054", "8049230", "8049230", "7569974", "7569974" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Edoardo Salladini", "Edoardo Salladini", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:1APL", "PDB:1MNM", "PDB:1YRN" ]
[ "pfam" ]
[ "PF00046" ]
[ "Homeodomain" ]
1
[ "ALPHA-2", "MAT2A", "MATAL2", "MATALPHA2", "YCR039C", "YCR39C" ]
[ 103, 113, 190, 206 ]
[ 112, 132, 205, 210 ]
[ "D", "T", "T", "D" ]
6
DP02808
P53927
UPI0000053239
Ribosome biogenesis protein 15
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
220
0.586364
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-22T02:59:53.136Z
lchemes
UniRef100_P53927
UniRef90_P53927
UniRef50_P53927
MVKSTSKTSTKETVTKQPTEEKPIQEKEELALETSSSSSDEEDEKDEDEIEGLAASDDEQSGTHKIKRLNPKKQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVRVLPKGAKIEKLYKYKKRVLVEKGITKPVKQLKDNMKQKHEERIKKLAKSGIEFKW
9
[ "DP02808r001", "DP02808r002", "DP02808r003", "DP02808r004", "DP02808r005", "DP02808r006", "DP02808r007", "DP02808r008", "DP02808r009" ]
[ 179, 181, 181, 181, 181, 1, 181, 181, 1 ]
[ 191, 220, 220, 220, 220, 87, 220, 220, 80 ]
[ 13, 40, 40, 40, 40, 87, 40, 40, 80 ]
[ "disorder", "disorder", "disorder", "disorder to order", "disorder to order", "disorder", "molecular function regulator", "RNA binding", "RNA binding" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000011", "IDPO:0000011", "IDPO:0000002", "GO:0098772", "GO:0003723", "GO:0003723" ]
[ "Structural state", "Structural state", "Structural state", "Structural transition", "Structural transition", "Structural state", "Molecular function", "Molecular function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006165", "ECO:0006210", "ECO:0005670", "ECO:0006208", "ECO:0006224", "ECO:0000269", "ECO:0000269", "ECO:0000269" ]
[ "27789691", "27789691", "27789691", "27789691", "27251291", "27251291", "27789691", "27789691", "27789691" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:3JCT", "PDB:5T9P" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.30.70.330", "PF00076" ]
[ "G3DSA:3.30.70.330", "RNA recognition motif" ]
2
[ "N1954", "NOP15", "YNL110C" ]
[ 1, 179, 181 ]
[ 87, 180, 220 ]
[ "D", "D", "T" ]
6
DP02809
P53193
UPI000013B023
J-type co-chaperone JAC1, mitochondrial
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
184
0.130435
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-22T15:37:39.278Z
fquaglia
UniRef100_P53193
UniRef90_P53193
UniRef50_P53193
MLKYLVQRRFTSTFYELFPKTFPKKLPIWTIDQSRLRKEYRQLQAQHHPDMAQQGSEQSSTLNQAYHTLKDPLRRSQYMLKLLRNIDLTQEQTSNEVTTSDPQLLLKVLDIHDELSQMDDEAGVKLLEKQNKERIQDIEAQLGQCYNDKDYAAAVKLTVELKYWYNLAKAFKDWAPGKQLEMNH
3
[ "DP02809r001", "DP02809r002", "DP02809r003" ]
[ 47, 91, 91 ]
[ 60, 100, 100 ]
[ 14, 10, 10 ]
[ "disorder", "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005670" ]
[ "22306468", "22306468", "22306468" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3UO2", "PDB:3UO3" ]
[ "gene3D", "gene3D", "pfam", "pfam" ]
[ "G3DSA:1.20.1280.20", "G3DSA:1.10.287.110", "PF00226", "PF07743" ]
[ "HscB, C-terminal domain", "DnaJ domain", "DnaJ domain", "HSCB C-terminal oligomerisation domain" ]
4
[ "JAC1", "SEO2", "YGL018C" ]
[ 47, 91 ]
[ 60, 100 ]
[ "D", "D" ]
2
DP02810
P02469
UPI000016CE91
Laminin subunit beta-1
Mus musculus
10,090
1,786
0.026316
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2023_12
2020-04-22T16:18:04.528Z
fquaglia
UniRef100_P02469
UniRef90_P02469
UniRef50_P07942
MGLLQVFAFGVLALWGTRVCAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICDSRDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKAWGVYRYFAYDCESSFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGVNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLP...
1
[ "DP02810r002" ]
[ 494 ]
[ 540 ]
[ 47 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "22860131" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:4AQS" ]
[ "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.120.1490", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00053", "PF00055", "PF21199", "PF23219", "PF24973", "PF24973" ]
[ "G3DSA:2.60.120.1490", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin EGF domain", "Laminin N-terminal (Domain...
17
[ "Lamb-1", "Lamb1", "Lamb1-1" ]
[ 494 ]
[ 540 ]
[ "D" ]
4
DP02811
Q8K419
UPI00000E61A0
Galectin-4
Mus musculus
10,090
326
0.033742
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-22T16:35:31.341Z
fquaglia
UniRef100_Q8K419
UniRef90_Q8K419
UniRef50_P56470
MAYVPAPGYQPTYNPTLPYKRPIPGGLSVGMSVYIQGMAKENMRRFHVNFAVGQDDGADVAFHFNPRFDGWDKVVFNTMQSGQWGKEEKKKSMPFQKGKHFELVFMVMPEHYKVVVNGNSFYEYGHRLPVQMVTHLQVDGDLELQSINFLGGQPAAAPYPGAMTIPAYPAGSPGYNPPQMNTLPVMTGPPVFNPRVPYVGALQGGLTVRRTIIIKGYVLPTARNFVINFKVGSSGDIALHLNPRIGDSVVRNSFMNGSWGAEERKVAYNPFGPGQFFDLSIRCGMDRFKVFANGQHLFDFSHRFQAFQMVDTLEINGDIT...
1
[ "DP02811r001" ]
[ 2 ]
[ 12 ]
[ 11 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "21358051" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:3I8T" ]
[ "pfam", "pfam" ]
[ "PF00337", "PF00337" ]
[ "Galactoside-binding lectin", "Galactoside-binding lectin" ]
2
[ "Lgals4" ]
[ 2 ]
[ 12 ]
[ "D" ]
9
DP02812
A6NI73
UPI0000034C06
Leukocyte immunoglobulin-like receptor subfamily A member 5
Homo sapiens
9,606
299
0.036789
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-22T16:52:49.122Z
fquaglia
UniRef100_A6NI73
UniRef90_A6NI73
UniRef50_A6NI73
MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR
3
[ "DP02812r001", "DP02812r002", "DP02812r003" ]
[ 147, 147, 147 ]
[ 157, 157, 157 ]
[ 11, 11, 11 ]
[ "disorder", "disorder", "glycosylation display site" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000041" ]
[ "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0006220" ]
[ "16675463", "16675463", "16675463" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:2D3V" ]
[ "gene3D", "gene3D", "pfam" ]
[ "G3DSA:2.60.40.10", "G3DSA:2.60.40.10", "PF13895" ]
[ "Immunoglobulins", "Immunoglobulins", "Immunoglobulin domain" ]
3
[ "ILT11", "LILRA5", "LILRB7", "LIR9" ]
[ 147 ]
[ 157 ]
[ "D" ]
5
DP02815
P62330
UPI0000027915
ADP-ribosylation factor 6
Homo sapiens
9,606
175
0.131429
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-22T18:33:44.955Z
lchemes
UniRef100_P62330
UniRef90_P62330
UniRef50_P62330
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
5
[ "DP02815r001", "DP02815r002", "DP02815r003", "DP02815r004", "DP02815r005" ]
[ 34, 34, 34, 34, 34 ]
[ 56, 56, 56, 56, 56 ]
[ 23, 23, 23, 23, 23 ]
[ "disorder", "disorder", "disorder", "disorder to order", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000011", "GO:0098772" ]
[ "Structural state", "Structural state", "Structural state", "Structural transition", "Molecular function" ]
[ "ECO:0006220", "ECO:0006165", "ECO:0006210", "ECO:0005670", "ECO:0005670" ]
[ "20709080", "20709080", "20709080", "20709080", "20709080" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:3N5C" ]
[ "pfam" ]
[ "PF00025" ]
[ "ADP-ribosylation factor family" ]
1
[ "ARF6" ]
[ 34 ]
[ 56 ]
[ "T" ]
9
DP02816
P48740-3
UPI000020A983
Isoform 3 of Mannan-binding lectin serine protease 1
Homo sapiens
9,606
380
0.044737
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-22T18:34:19.507Z
fquaglia
MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYF...
1
[ "DP02816r001" ]
[ 364 ]
[ 380 ]
[ 17 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "22854970" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[]
[]
[]
[]
0
[ "CRARF", "CRARF1", "MASP1", "PRSS5" ]
[ 364 ]
[ 380 ]
[ "D" ]
3
DP02817
Q64373
UPI000002103C
Bcl-2-like protein 1
Mus musculus
10,090
233
0.23176
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-22T19:24:17.749Z
lchemes
UniRef100_Q64373
UniRef90_Q64373
UniRef50_Q64373
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEAERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
2
[ "DP02817r001", "DP02817r002" ]
[ 28, 28 ]
[ 81, 81 ]
[ 54, 54 ]
[ "disorder", "molecular recognition display site" ]
[ "IDPO:0000002", "IDPO:0000037" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0007719" ]
[ "20206602", "29694915" ]
[ "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:3IHC" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:1.10.437.10", "PF00452", "PF02180" ]
[ "Blc2-like", "Apoptosis regulator proteins, Bcl-2 family", "Bcl-2 homology region 4" ]
3
[ "Bcl2l", "Bcl2l1", "Bclx" ]
[ 28 ]
[ 81 ]
[ "D" ]
6
DP02818
Q07157
UPI000013C445
Tight junction protein ZO-1
Homo sapiens
9,606
1,748
0.597826
[ "Condensates-related proteins" ]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-04-23T14:21:04.297Z
fquaglia
UniRef100_Q07157
UniRef90_Q07157
UniRef50_Q07157
MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPDPEPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSGRSHDRPPRRSRSRSPDQRS...
5
[ "DP02818r001", "DP02818r002", "DP02818r003", "DP02818r004", "DP02818r005" ]
[ 589, 589, 675, 265, 795 ]
[ 627, 627, 687, 420, 1631 ]
[ 39, 39, 13, 156, 837 ]
[ "disorder", "flexible linker", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0005670", "ECO:0006220", "ECO:0000302", "ECO:0000302" ]
[ "22030391", "22030391", "22030391", "30354300", "33806674" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Victoria Nugnes", "Victoria Nugnes" ]
[ "PDB:3TSW", "PDB:3TSZ" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.30.42.10", "G3DSA:2.30.42.10", "G3DSA:2.30.42.10", "PF00595", "PF00595", "PF00595", "PF00625", "PF00791", "PF07653" ]
[ "G3DSA:2.30.42.10", "G3DSA:2.30.42.10", "G3DSA:2.30.42.10", "PDZ domain", "PDZ domain", "PDZ domain", "Guanylate kinase", "ZU5 domain", "Variant SH3 domain" ]
9
[ "TJP1", "ZO1" ]
[ 265, 589, 675, 795 ]
[ 420, 627, 687, 1631 ]
[ "D", "D", "D", "D" ]
3
DP02819
Q62420
UPI0000029023
Endophilin-A1
Mus musculus
10,090
352
0.130682
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-23T15:36:33.663Z
fquaglia
UniRef100_Q62420
UniRef90_O35179
UniRef50_O35179
MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFATGDSTQPNGGLSHTGTPKPPGVQMDQPCCRALYDFEPENEGELGFKEGDIITLT...
3
[ "DP02819r001", "DP02819r002", "DP02819r003" ]
[ 1, 67, 67 ]
[ 26, 86, 86 ]
[ 26, 20, 20 ]
[ "disorder", "disorder", "molecular function regulator" ]
[ "IDPO:0000002", "IDPO:0000002", "GO:0098772" ]
[ "Structural state", "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006220", "ECO:0005670" ]
[ "16023669", "16023669", "16023669" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1ZWW" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:1.20.1270.60", "PF00018", "PF03114" ]
[ "Arfaptin homology (AH) domain/BAR domain", "SH3 domain", "BAR domain" ]
3
[ "Een1", "Sh3d2a", "Sh3gl2" ]
[ 1, 67 ]
[ 26, 86 ]
[ "D", "D" ]
3
DP02820
Q62264
UPI00000040AA
Thyroid hormone-inducible hepatic protein
Mus musculus
10,090
150
0.186667
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2021_06
2020-04-23T16:06:02.862Z
fquaglia
UniRef100_Q62264
UniRef90_Q62264
UniRef50_Q62264
MQVLTKRYPKNCLLTVMDRYSAVVRNMEQVVMIPSLLRDVQLSGPGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPREEWQAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTGQVL
3
[ "DP02820r001", "DP02820r002", "DP02820r003" ]
[ 77, 1, 1 ]
[ 104, 150, 150 ]
[ 28, 150, 150 ]
[ "disorder", "protein binding", "molecular function inhibitor activity" ]
[ "IDPO:0000002", "GO:0005515", "GO:0140678" ]
[ "Structural state", "Molecular function", "Molecular function" ]
[ "ECO:0006220", "ECO:0006030", "ECO:0007689" ]
[ "20952656", "20952656", "20952656" ]
[ "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3ONT" ]
[ "pfam" ]
[ "PF07084" ]
[ "Thyroid hormone-inducible hepatic protein Spot 14" ]
1
[ "S14", "Thrsp" ]
[ 1, 77, 105 ]
[ 76, 104, 150 ]
[ "F", "D", "F" ]
7
DP02824
Q14019
UPI0000505468
Coactosin-like protein
Homo sapiens
9,606
142
0.077465
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-24T08:56:15.626Z
fquaglia
UniRef100_Q14019
UniRef90_Q14019
UniRef50_Q14019
MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKSELKKAGGANYDAQTE
2
[ "DP02824r001", "DP02824r002" ]
[ 132, 132 ]
[ 142, 142 ]
[ 11, 11 ]
[ "disorder", "molecular adaptor activity" ]
[ "IDPO:0000002", "GO:0060090" ]
[ "Structural state", "Molecular function" ]
[ "ECO:0006220", "ECO:0006218" ]
[ "15459340", "15459340" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1VFQ" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.40.20.10", "PF00241" ]
[ "Severin", "Cofilin/tropomyosin-type actin-binding protein" ]
2
[ "CLP", "COTL1" ]
[ 132 ]
[ 142 ]
[ "D" ]
5
DP02825
P31153
UPI0000000C32
S-adenosylmethionine synthase isoform type-2
Homo sapiens
9,606
395
0.035443
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-24T09:21:28.736Z
fquaglia
UniRef100_P31153
UniRef90_P31153
UniRef50_P31153
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSY...
5
[ "DP02825r001", "DP02825r002", "DP02825r003", "DP02825r004", "DP02825r005" ]
[ 116, 116, 116, 116, 117 ]
[ 126, 126, 126, 126, 129 ]
[ 11, 11, 11, 11, 13 ]
[ "disorder", "entropic chain", "small molecule binding", "disorder to order", "disorder" ]
[ "IDPO:0000002", "IDPO:0000030", "GO:0036094", "IDPO:0000011", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Molecular function", "Structural transition", "Structural state" ]
[ "ECO:0006220", "ECO:0005670", "ECO:0005670", "ECO:0005670", "ECO:0006220" ]
[ "26858410", "26858410", "26858410", "26858410", "28553945" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5A19", "PDB:5A1G", "PDB:5A1I", "PDB:5UGH" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00438", "PF02772", "PF02773" ]
[ "S-adenosylmethionine synthetase, N-terminal domain", "S-adenosylmethionine synthetase, central domain", "S-adenosylmethionine synthetase, C-terminal domain" ]
3
[ "AMS2", "MAT2A", "MATA2" ]
[ 116, 127 ]
[ 126, 129 ]
[ "T", "D" ]
7
DP02826
P40344
UPI0000052F5F
Autophagy-related protein 3
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
559,292
310
0.445161
[ "Autophagy-related proteins" ]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Saccharomycotina", "Saccharomycetes", "Saccharomycetales", "Saccharomycetaceae", "Saccharomyces" ]
2021_06
2020-04-24T10:57:25.089Z
vsagris
UniRef100_A6ZS81
UniRef90_A6ZS81
UniRef50_W0TEF9
MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDEDDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIKEEDENDDTEEFNAKGGLAKDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDDIDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW
15
[ "DP02826r001", "DP02826r002", "DP02826r003", "DP02826r004", "DP02826r005", "DP02826r006", "DP02826r008", "DP02826r009", "DP02826r010", "DP02826r011", "DP02826r012", "DP02826r014", "DP02826r015", "DP02826r016", "DP02826r017" ]
[ 1, 84, 143, 84, 84, 129, 1, 84, 142, 247, 270, 270, 82, 82, 82 ]
[ 20, 128, 162, 162, 162, 142, 20, 128, 162, 280, 273, 273, 165, 165, 165 ]
[ 20, 45, 20, 79, 79, 14, 20, 45, 21, 34, 4, 4, 84, 84, 84 ]
[ "disorder", "disorder", "disorder", "disorder", "protein binding", "molten globule", "disorder", "disorder", "disorder", "disorder", "protein binding", "selective autophagy", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0005515", "IDPO:0000003", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0005515", "GO:0061912", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Structural state", "Structural state", "Structural state", "Molecular function", "Structural state", "Structural state", "Structural state", "Structural state", "Structural state", "Molecular function", "Biological process", "Structural state", "Structural state", "S...
[ "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006165", "ECO:0006077", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0006165", "ECO:0006165", "ECO:0007064", "ECO:0006200", "ECO:0007689" ]
[ "17227760", "17227760", "17227760", "17227760", "17227760", "17227760", "23142976", "23142976", "23142976", "23142976", "20615880", "20615880", "24879155", "24879155", "24879155" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Edoardo Salladini", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Vasileios Sagris", "Vasileios Sagris", "Victoria Nugnes", "Victoria Nugnes", "Victoria...
[ "PDB:2DYT", "PDB:4GSL" ]
[ "pfam" ]
[ "PF03987" ]
[ "Autophagocytosis associated protein, active-site domain" ]
1
[ "APG3", "ATG3", "AUT1", "N2040", "YNR007C" ]
[ 1, 82, 247 ]
[ 20, 165, 280 ]
[ "D", "D", "D" ]
3
DP02827
P22523
UPI000016F30F
Chromosome partition protein MukB
Escherichia coli (strain K12)
83,333
1,486
0.012113
[]
[ "Bacteria", "Proteobacteria", "Gammaproteobacteria", "Enterobacterales", "Enterobacteriaceae", "Escherichia" ]
2023_12
2020-04-24T14:42:41.968Z
fquaglia
UniRef100_C4ZQ50
UniRef90_B5QZC8
UniRef50_Q935S7
MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHN...
1
[ "DP02827r001" ]
[ 59 ]
[ 76 ]
[ 18 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "10545328" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:1QHL" ]
[ "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:1.20.1060.30", "PF04310", "PF13558", "PF16330" ]
[ "G3DSA:1.20.1060.30", "MukB N-terminal", "SbcC/RAD50-like, Walker B motif", "MukB hinge domain" ]
4
[ "JW0907", "b0924", "mukB" ]
[ 59 ]
[ 76 ]
[ "D" ]
7
DP02829
P46379
UPI00001267A0
Large proline-rich protein BAG6
Homo sapiens
9,606
1,132
0.628092
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2023_12
2020-04-27T08:49:10.782Z
fquaglia
UniRef100_P46379
UniRef90_P46379
UniRef50_P46379
MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMETLPYLQCRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQ...
9
[ "DP02829r001", "DP02829r002", "DP02829r003", "DP02829r004", "DP02829r005", "DP02829r006", "DP02829r007", "DP02829r008", "DP02829r009" ]
[ 1057, 1048, 1048, 1048, 1048, 1048, 1048, 1048, 395 ]
[ 1112, 1123, 1123, 1123, 1123, 1123, 1123, 1123, 1029 ]
[ 56, 76, 76, 76, 76, 76, 76, 76, 635 ]
[ "disorder to order", "protein binding", "disorder", "disorder to order", "protein binding", "molecular function activator activity", "molecular adaptor activity", "protein binding", "disorder" ]
[ "IDPO:0000011", "GO:0005515", "IDPO:0000002", "IDPO:0000011", "GO:0005515", "GO:0140677", "GO:0060090", "GO:0005515", "IDPO:0000002" ]
[ "Structural transition", "Molecular function", "Structural state", "Structural transition", "Molecular function", "Molecular function", "Molecular function", "Molecular function", "Structural state" ]
[ "ECO:0005670", "ECO:0005670", "ECO:0006204", "ECO:0006204", "ECO:0006210", "ECO:0000279", "ECO:0005670", "ECO:0001269", "ECO:0000302" ]
[ "25713138", "25713138", "25713138", "25713138", "25713138", "25713138", "25713138", "25713138", "34523930" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Victoria Nugnes" ]
[ "PDB:4X86" ]
[ "pfam", "pfam", "pfam" ]
[ "PF00240", "PF12057", "PF20960" ]
[ "Ubiquitin family", "BCL2-associated athanogene 6", "Bag6, BAG-similar domain" ]
3
[ "BAG6", "BAT3", "G3" ]
[ 395, 1048 ]
[ 1029, 1123 ]
[ "D", "T" ]
5
DP02830
Q91YD9
UPI000002967C
Neural Wiskott-Aldrich syndrome protein
Mus musculus
10,090
501
0.01996
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2020_12
2020-04-27T09:25:32.363Z
fquaglia
UniRef100_Q91YD9
UniRef90_O08816
UniRef50_O00401
MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWAKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDAPNGPNLPMATVDIKNPEITTNRFYGSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPP...
2
[ "DP02830r001", "DP02830r002" ]
[ 419, 419 ]
[ 428, 428 ]
[ 10, 10 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0005670" ]
[ "20804767", "20804767" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:3M3N" ]
[ "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.30.29.30", "G3DSA:3.90.810.10", "G3DSA:3.90.810.10", "PF00568", "PF00786", "PF02205", "PF02205" ]
[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "CRIB domain", "CRIB domain", "WH1 domain", "P21-Rho-binding domain", "WH2 motif", "WH2 motif" ]
7
[ "Wasl" ]
[ 419 ]
[ 428 ]
[ "D" ]
2
DP02831
Q13164
UPI000012F179
Mitogen-activated protein kinase 7
Homo sapiens
9,606
816
0.056373
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2020_12
2020-04-27T09:39:19.253Z
fquaglia
UniRef100_Q13164
UniRef90_Q13164
UniRef50_Q13164
MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQA...
2
[ "DP02831r001", "DP02831r002" ]
[ 1, 1 ]
[ 46, 46 ]
[ 46, 46 ]
[ "disorder", "localization" ]
[ "IDPO:0000002", "GO:0051179" ]
[ "Structural state", "Biological process" ]
[ "ECO:0006220", "ECO:0006218" ]
[ "23656407", "23656407" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4B99" ]
[ "pfam" ]
[ "PF00069" ]
[ "Protein kinase domain" ]
1
[ "BMK1", "ERK5", "MAPK7", "PRKM7" ]
[ 1 ]
[ 46 ]
[ "D" ]
1
DP02832
Q7L2J0
UPI0000227DFA
7SK snRNA methylphosphate capping enzyme
Homo sapiens
9,606
689
0.11611
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-27T10:10:09.300Z
fquaglia
UniRef100_Q7L2J0
UniRef90_Q7L2J0
UniRef50_Q7L2J0
MIEMAAEKEPFLVPAPPPPLKDESGGGGGPTVPPHQEAASGELRGGTERGPGRCAPSAGSPAAAVGRESPGAAATSSSGPQAQQHRGGGPQAQSHGEARLSDPPGRAAPPDVGEERRGGGGTELGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGGGGGFKHPAFKRRRRVNSDCDSVLPSNFLLGGNIFDPLNLNSLLDEEVSRTLNAETPKSSPLPAKGRDPVEILIPKDITDPLSLNTCTDEGHVVLASPLKTGRKRHRHRGQHHQQQQAAGGSESHPVPPTAPLTPLLHGEGASQQPRHRGQNRDAPQPYELNT...
7
[ "DP02832r001", "DP02832r002", "DP02832r003", "DP02832r004", "DP02832r005", "DP02832r006", "DP02832r007" ]
[ 492, 400, 400, 418, 418, 665, 665 ]
[ 545, 689, 689, 431, 431, 676, 676 ]
[ 54, 290, 290, 14, 14, 12, 12 ]
[ "disorder", "RNA binding", "molecular function regulator", "disorder", "disorder to order", "disorder to order", "disorder" ]
[ "IDPO:0000002", "GO:0003723", "GO:0098772", "IDPO:0000002", "IDPO:0000011", "IDPO:0000011", "IDPO:0000002" ]
[ "Structural state", "Molecular function", "Molecular function", "Structural state", "Structural transition", "Structural transition", "Structural state" ]
[ "ECO:0006220", "ECO:0005647", "ECO:0005647", "ECO:0006220", "ECO:0005670", "ECO:0005670", "ECO:0006220" ]
[ "30559425", "30559425", "30559425", "30559425", "30559425", "30559425", "30559425" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Edoardo Salladini", "Edoardo Salladini", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:6DCB", "PDB:6DCC" ]
[ "pfam" ]
[ "PF06859" ]
[ "Bicoid-interacting protein 3 (Bin3)" ]
1
[ "BCDIN3", "MEPCE" ]
[ 400, 418, 432, 492, 546, 665, 677 ]
[ 417, 431, 491, 545, 664, 676, 689 ]
[ "F", "T", "F", "D", "F", "T", "F" ]
4
DP02833
Q9Y4F1
UPI000007052C
FERM, ARHGEF and pleckstrin domain-containing protein 1
Homo sapiens
9,606
1,045
0.045933
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-27T11:29:13.954Z
fquaglia
UniRef100_Q9Y4F1
UniRef90_Q9Y4F1
UniRef50_F1LYQ8
MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFE...
2
[ "DP02833r001", "DP02833r002" ]
[ 862, 862 ]
[ 909, 909 ]
[ 48, 48 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0005670" ]
[ "23375260", "23375260" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:4H6Y" ]
[ "gene3D", "gene3D", "gene3D", "gene3D", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.30.29.30", "G3DSA:2.30.29.30", "G3DSA:1.20.80.10", "G3DSA:1.20.900.10", "PF00169", "PF00169", "PF00373", "PF00621", "PF08736", "PF09379", "PF09380" ]
[ "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)", "G3DSA:1.20.80.10", "Dbl homology (DH) domain", "PH domain", "PH domain", "FERM central domain", "RhoGEF domain", "FERM adjacent (FA)", "FER...
11
[ "CDEP", "FARP1", "PLEKHC2" ]
[ 862 ]
[ 909 ]
[ "D" ]
2
DP02834
Q9Y2Z0
UPI00001CDFF4
Protein SGT1 homolog
Homo sapiens
9,606
365
0.041096
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-27T22:38:47.940Z
fquaglia
UniRef100_Q9Y2Z0
UniRef90_Q9Y2Z0
UniRef50_Q9Y2Z0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKYDWYQTESQVVITLMIKNVQKNDVNVEFSEKELSALVKLPSGEDYNLKLELLHPIIPEQSTFKVLSTKIEIKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWDKLVGEIKEEEKNEKLEGDAALNRLFQQIYSDG...
4
[ "DP02834r001", "DP02834r002", "DP02834r003", "DP02834r004" ]
[ 262, 262, 262, 262 ]
[ 276, 276, 276, 276 ]
[ 15, 15, 15, 15 ]
[ "disorder", "disorder", "flexible linker", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000033", "IDPO:0000033" ]
[ "Structural state", "Structural state", "Disorder function", "Disorder function" ]
[ "ECO:0006165", "ECO:0006220", "ECO:0005670", "ECO:0006165" ]
[ "14761955", "14761955", "14761955", "14761955" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:1RL1" ]
[ "gene3D", "gene3D", "pfam", "pfam", "pfam" ]
[ "G3DSA:2.60.40.790", "G3DSA:1.25.40.10", "PF04969", "PF05002", "PF13432" ]
[ "G3DSA:2.60.40.790", "G3DSA:1.25.40.10", "CS domain", "SGS domain", "Tetratricopeptide repeat" ]
5
[ "SUGT1" ]
[ 262 ]
[ 276 ]
[ "D" ]
3
DP02835
Q14849
UPI000012F1BC
StAR-related lipid transfer protein 3
Homo sapiens
9,606
445
0.033708
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-27T22:49:50.808Z
fquaglia
UniRef100_Q14849
UniRef90_Q14849
UniRef50_Q14849
MSKLPRELTRDLERSLPAVASLGSSLSHSQSLSSHLLPPPEKRRAISDVRRTFCLFVTFDLLFISLLWIIELNTNTGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLRLRHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQVAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQIL...
2
[ "DP02835r001", "DP02835r002" ]
[ 216, 216 ]
[ 230, 230 ]
[ 15, 15 ]
[ "disorder", "flexible linker" ]
[ "IDPO:0000002", "IDPO:0000033" ]
[ "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0006220" ]
[ "27487925", "27487925" ]
[ "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5I9J" ]
[ "gene3D", "pfam", "pfam" ]
[ "G3DSA:3.30.530.20", "PF01852", "PF10457" ]
[ "G3DSA:3.30.530.20", "START domain", "Cholesterol-capturing domain" ]
3
[ "CAB1", "MLN64", "STARD3" ]
[ 216 ]
[ 230 ]
[ "D" ]
4
DP02836
P24785
UPI000012F1F4
Dosage compensation regulator
Drosophila melanogaster
7,227
1,293
0.239753
[]
[ "Eukaryota", "Metazoa", "Ecdysozoa", "Arthropoda", "Hexapoda", "Insecta", "Pterygota", "Neoptera", "Endopterygota", "Diptera", "Brachycera", "Muscomorpha", "Ephydroidea", "Drosophilidae", "Drosophila", "Sophophora" ]
2021_06
2020-04-28T09:00:55.520Z
fquaglia
UniRef100_P24785
UniRef90_P24785
UniRef50_P24785
MDIKSFLYQFCAKSQIEPKFDIRQTGPKNRQRFLCEVRVEPNTYIGVGNSTNKKDAEKNACRDFVNYLVRVGKLNTNDVPADAGASGGGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLGEAYRPLNHDGGDGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHGNWTIENAKERLNIYKQTNNIRDDYKYTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVIEPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEVIKGLDLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKR...
6
[ "DP02836r001", "DP02836r002", "DP02836r003", "DP02836r004", "DP02836r005", "DP02836r006" ]
[ 81, 81, 1, 311, 1159, 1 ]
[ 164, 164, 142, 321, 1293, 104 ]
[ 84, 84, 142, 11, 135, 104 ]
[ "disorder", "flexible linker", "disorder", "disorder", "disorder", "disorder" ]
[ "IDPO:0000002", "IDPO:0000033", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000002" ]
[ "Structural state", "Disorder function", "Structural state", "Structural state", "Structural state", "Structural state" ]
[ "ECO:0006220", "ECO:0005670", "ECO:0006220", "ECO:0006220", "ECO:0006220", "ECO:0007691" ]
[ "30649456", "30649456", "26545078", "26545078", "26545078", "26545078" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia", "Federica Quaglia" ]
[ "PDB:5AOR", "PDB:5ZTM" ]
[ "pfam", "pfam", "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "PF00035", "PF00035", "PF00270", "PF00271", "PF04408", "PF07717", "PF21010" ]
[ "Double-stranded RNA binding motif", "Double-stranded RNA binding motif", "DEAD/DEAH box helicase", "Helicase conserved C-terminal domain", "Helicase associated domain (HA2), winged-helix", "Oligonucleotide/oligosaccharide-binding (OB)-fold", "Helicase associated domain (HA2), ratchet-like" ]
7
[ "CG11680", "mle", "nap" ]
[ 1, 311, 1159 ]
[ 164, 321, 1293 ]
[ "D", "D", "D" ]
9
DP02837
Q9QXN5
UPI0000029CB4
Inositol oxygenase
Mus musculus
10,090
285
0.098246
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Glires", "Rodentia", "Myomorpha", "Muroidea", "Muridae", "Murinae", "Mus", "Mus" ]
2023_12
2020-04-28T11:07:23.461Z
fquaglia
UniRef100_Q9QXN5
UniRef90_Q9QXN5
UniRef50_Q9QXN5
MKVDVGPDPSLVYRPDVDPEMAKSKDSFRNYTSGPLLDRVFTTYKLMHTHQTVDFVSRKRIQYGSFSYKKMTIMEAVGMLDDLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKIMALWGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLENVLMSWGHDEYLYQMMKFNKFSLPSEAFYMIRFHSFYPWHTGGDYRQLCSQQDLDMLPWVQEFNKFDLYTKCPDLPDVESLRPYYQGLIDKYCPGTLSW
1
[ "DP02837r001" ]
[ 1 ]
[ 28 ]
[ 28 ]
[ "disorder" ]
[ "IDPO:0000002" ]
[ "Structural state" ]
[ "ECO:0006220" ]
[ "17012379" ]
[ "pmid" ]
[ "Federica Quaglia" ]
[ "PDB:2HUO" ]
[ "pfam" ]
[ "PF05153" ]
[ "Myo-inositol oxygenase" ]
1
[ "Aldrl6", "Miox", "Rsor" ]
[ 1 ]
[ 28 ]
[ "D" ]
7
DP02838
P20807
UPI000000103F
Calpain-3
Homo sapiens
9,606
821
0.063337
[]
[ "Eukaryota", "Metazoa", "Chordata", "Craniata", "Vertebrata", "Euteleostomi", "Mammalia", "Eutheria", "Euarchontoglires", "Primates", "Haplorrhini", "Catarrhini", "Hominidae", "Homo" ]
2021_06
2020-04-29T14:43:29.736Z
lchemes
UniRef100_P20807
UniRef90_P20807
UniRef50_P20807
MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQDSDLDPRGSDERPTRTIIPV...
4
[ "DP02838r001", "DP02838r002", "DP02838r003", "DP02838r004" ]
[ 269, 269, 269, 269 ]
[ 320, 320, 320, 320 ]
[ 52, 52, 52, 52 ]
[ "disorder", "disorder", "disorder", "self-inhibition" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "IDPO:0000059" ]
[ "Structural state", "Structural state", "Structural state", "Disorder function" ]
[ "ECO:0006220", "ECO:0007691", "ECO:0006210", "ECO:0005670" ]
[ "29382717", "29382717", "29382717", "29382717" ]
[ "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:6BDT", "PDB:6BGP", "PDB:6BJD" ]
[ "pfam", "pfam", "pfam", "pfam", "pfam" ]
[ "PF00648", "PF01067", "PF13833", "PF16648", "PF21875" ]
[ "Calpain family cysteine protease", "Calpain large subunit, domain III", "EF-hand domain pair", "Unstructured region on Calpain-3", "Calpain-13-like, C-terminal EF-hand" ]
5
[ "CANP3", "CANPL3", "CAPN3", "NCL1" ]
[ 269 ]
[ 320 ]
[ "D" ]
8
DP02839
O43070
UPI00001620EC
DNA repair and telomere maintenance protein nbs1
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
284,812
613
0.384992
[]
[ "Eukaryota", "Fungi", "Dikarya", "Ascomycota", "Taphrinomycotina", "Schizosaccharomycetes", "Schizosaccharomycetales", "Schizosaccharomycetaceae", "Schizosaccharomyces" ]
2021_06
2020-04-29T15:24:09.849Z
lchemes
UniRef100_O43070
UniRef90_O43070
UniRef50_O43070
MWIIEAEGDILKGKSRILFPGTYIVGRNVSDDSSHIQVISKSISKRHARFTILTPSEKDYFTGGPCEFEVKDLDTKFGTKVNEKVVGQNGDSYKEKDLKIQLGKCPFTINAYWRSMCIQFDNPEMLSQWASNLNLLGIPTGLRDSDATTHFVMNRQAGSSITVGTMYAFLKKTVIIDDSYLQYLSTVKESVIEDASLMPDALECFKNIIKNNDQFPSSPEDCINSLEGFSCAMLNTSSESHHLLELLGLRISTFMSLGDIDKELISKTDFVVLNNAVYDSEKISFPEGIFCLTIEQLWKIIIERNSRELISKEIERLKYA...
8
[ "DP02839r001", "DP02839r002", "DP02839r003", "DP02839r004", "DP02839r005", "DP02839r006", "DP02839r007", "DP02839r008" ]
[ 330, 330, 275, 330, 474, 477, 477, 477 ]
[ 553, 553, 286, 553, 531, 526, 526, 526 ]
[ 224, 224, 12, 224, 58, 50, 50, 50 ]
[ "disorder", "disorder", "disorder", "molecular adaptor activity", "disorder", "disorder to order", "protein binding", "molecular adaptor activity" ]
[ "IDPO:0000002", "IDPO:0000002", "IDPO:0000002", "GO:0060090", "IDPO:0000002", "IDPO:0000011", "GO:0005515", "GO:0060090" ]
[ "Structural state", "Structural state", "Structural state", "Molecular function", "Structural state", "Structural transition", "Molecular function", "Molecular function" ]
[ "ECO:0007691", "ECO:0006210", "ECO:0006220", "ECO:0006210", "ECO:0007689", "ECO:0005670", "ECO:0005670", "ECO:0005670" ]
[ "19804755", "19804755", "19804755", "19804755", "22705791", "22705791", "22705791", "22705791" ]
[ "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid", "pmid" ]
[ "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes", "Lucia Chemes" ]
[ "PDB:3HUE", "PDB:4FBK", "PDB:4FBQ", "PDB:4FBW" ]
[ "gene3D", "pfam" ]
[ "G3DSA:3.40.50.10190", "PF00498" ]
[ "BRCT domain", "FHA domain" ]
2
[ "SPBC6B1.09c", "nbs1" ]
[ 275, 330, 477, 527 ]
[ 286, 476, 526, 553 ]
[ "D", "D", "T", "D" ]
3