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string
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string
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string
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string
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string
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string
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int64
split
string
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string
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int64
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int64
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int64
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int64
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int64
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string
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string
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int64
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string
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float64
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string
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bool
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bool
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float64
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float64
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int64
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string
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string
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float64
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float64
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float64
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string
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float64
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float64
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float64
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float64
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string
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string
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fireprotdb:18742
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,742
train
mutant
476,125
358
477,477
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19V
E19V
1
1
0
0
19
E
V
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,421
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.100319
0.045911
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123524,"numValue":-0.10031886210384,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123525,"numValue":0.0459110521504868,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18743
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,743
train
mutant
476,126
358
477,478
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19I
E19I
1
1
0
0
19
E
I
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,749
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365131,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365132,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365133,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18744
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,744
train
mutant
476,126
358
477,478
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19I
E19I
1
1
0
0
19
E
I
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,411
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.1567
0.056576
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123504,"numValue":-0.15670041909571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123505,"numValue":0.0565763077857444,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18745
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,745
train
mutant
476,127
358
477,479
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19W
E19W
1
1
0
0
19
E
W
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,750
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365134,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365135,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365136,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18746
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,746
train
mutant
476,127
358
477,479
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19W
E19W
1
1
0
0
19
E
W
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,422
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.210992
0.034881
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123526,"numValue":-0.210992293690478,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123527,"numValue":0.0348810435875118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18747
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,747
train
mutant
476,128
358
477,480
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19Y
E19Y
1
1
0
0
19
E
Y
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,751
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365137,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365138,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365139,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18748
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,748
train
mutant
476,128
358
477,480
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19Y
E19Y
1
1
0
0
19
E
Y
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,423
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.175055
0.069662
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123528,"numValue":-0.175054908597709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123529,"numValue":0.0696622338453352,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18749
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,749
train
mutant
476,129
358
477,481
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19F
E19F
1
1
0
0
19
E
F
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,752
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.746501
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365140,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365141,"numValue":1.746500698020955,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365142,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18750
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,750
train
mutant
476,129
358
477,481
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19F
E19F
1
1
0
0
19
E
F
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,408
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.168619
0.053146
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123498,"numValue":-0.168619030290459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123499,"numValue":0.0531459533671457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18751
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,751
train
mutant
476,130
358
477,482
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19P
E19P
1
1
0
0
19
E
P
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,753
MegaScale
null
null
null
null
2.125906
null
null
null
null
null
null
0.545431
-0.567816
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365143,"numValue":0.5454307270741929,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365144,"numValue":-0.5678163144135377,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365145,"numValue":2.1259061119876863,"references":[],"strValue":null,"...
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18752
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,752
train
mutant
476,130
358
477,482
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19P
E19P
1
1
0
0
19
E
P
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,065,416
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-1.055482
0.106712
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123514,"numValue":-1.05548212260456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123515,"numValue":0.106711683262785,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18753
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,753
train
mutant
476,131
358
477,483
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19C
E19C
1
1
0
0
19
E
C
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,754
MegaScale
null
null
null
null
4.955969
null
null
null
null
null
null
2.014883
1.218577
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365146,"numValue":2.0148831635065623,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365147,"numValue":1.2185766486468248,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365148,"numValue":4.955968796432537,"references":[],"strValue":null,"ty...
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18754
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,754
train
mutant
476,131
358
477,483
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E19C
E19C
1
1
0
0
19
E
C
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,064,447
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.015056
0.042625
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121576,"numValue":-0.015055894864012,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121577,"numValue":0.0426254666594455,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18756
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,756
train
mutant
476,133
358
477,485
67
68
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
insA19
insA19
1
0
0
1
19
-
A
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,756
MegaScale
null
null
null
null
3.633693
null
null
null
null
null
null
1.374867
0.441964
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365152,"numValue":1.3748665706899623,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365153,"numValue":0.4419640187053731,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365154,"numValue":3.633692790589104,"references":[],"strValue":null,"ty...
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18757
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,757
train
mutant
476,134
358
477,486
67
66
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
delE19
delE19
1
0
1
0
19
E
-
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
501,757
MegaScale
null
null
null
null
2.879798
null
null
null
null
null
null
0.957364
-0.073448
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365155,"numValue":0.9573643461922214,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365156,"numValue":-0.0734481155381744,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365157,"numValue":2.879798182694797,"references":[],"strValue":null,"t...
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18758
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,758
train
mutant
476,134
358
477,486
67
66
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
delE19
delE19
1
0
1
0
19
E
-
3
CONSERVATION
1CSP
247
null
19
A
E
false
false
82.990571
44.277778
5,064,445
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-1.055621
0.096553
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121572,"numValue":-1.05562081323668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121573,"numValue":0.0965529563363102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20827,"numValue":3.0,"position":19,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18759
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,759
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,063
ProTherm
7.5
DSC
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:V20K
29.1
null
null
null
16.49
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|EASE-MM_S1676.csv|STRUM_Q3421.csv|HotMuSiC_S1626.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:V20K","t...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7737,"numValue":29.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AU...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18760
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,760
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,086
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:V20K
35.5
null
null
null
null
null
24.38
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|HotMuSiC_S1626.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:V20K","ty...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7806,"numValue":35.5,"references":[],"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18761
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,761
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,087
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:V20K
26.5
null
null
null
null
null
16.25
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|EASE-MM_S1676.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:V20K","ty...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7809,"numValue":26.5,"references":[],"strValue":null,"type":"TM"},{"datasets":["AU...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18762
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,762
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,131
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.05 M
1CSP_A:V20K
37.2
null
null
null
null
null
25.81
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S1810.csv|M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7941,"numValue":37.2,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7942,"numValue":25.81,"references":[],"strValue":null,"type":"DHVH"},{"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18763
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,763
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,132
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.05 M
1CSP_A:V20K
29.3
null
null
null
null
null
18.64
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S1810.csv|M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7944,"numValue":29.3,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7945,"numValue":18.64,"references":[],"strValue":null,"type":"DHVH"},{"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18764
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,764
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,177
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:V20K
37.3
null
null
null
null
null
25.81
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|EASE-MM_S1676.csv|M47andM8_S1810.csv|PON-TStab_dataset.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8079,"numValue":37.3,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1925.csv","I_...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18765
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,765
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,178
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:V20K
30
null
null
null
null
null
19.12
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","STRUM_Q3421.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8082,"numValue":30.0,"references":[],"str...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18766
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,766
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,223
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.2 M
1CSP_A:V20K
38.5
null
null
null
null
null
27.01
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|SVM-WIN31_SVM-3D12_S499.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8217,"numValue":38.5,"references":[],"strValue":null,"type":"TM"},{"datasets":["M4...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18767
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,767
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,224
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.2 M
1CSP_A:V20K
31.5
null
null
null
null
null
20.55
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv|AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":8220,"numValue":31.5,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":8221,"numValue":20.55,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18768
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,768
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,269
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.5 M
1CSP_A:V20K
41.7
null
null
null
null
null
29.64
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1962.csv|Saraboji_S2204.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv","STRUM_Q3421.csv"],"id":8355,"numValue":41.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv","STRUM_Q3421.csv"],"id":8356,"numValue":29.64,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["AUTOMUTE_S19...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18769
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,769
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,270
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.5 M
1CSP_A:V20K
36
null
null
null
null
null
24.14
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1962.csv|Saraboji_S2204.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":8358,"numValue":36.0,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":8359,"numValue":24.14,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":8...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18770
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,770
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,315
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:V20K
46.3
null
null
null
null
null
33.46
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1962.csv|PoPMuSiC-2.0_S2648.csv|Saraboji_S2204.csv|STRUM_Q3421.csv|AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1962.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S2204.csv","STRUM_Q3421.csv"],"id":8493,"numValue":46.3,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1962.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S2204.csv"],"id":8494,"numValue":33.46,"references":[],"strValue":null,"type":"D...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18771
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,771
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,316
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:V20K
39.6
null
null
null
null
null
27.25
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|AUTOMUTE_S1962.csv|EASE-MM_S1676.csv|HotMuSiC_S1626.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|Saraboji_S2204.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","AUTOMUTE_S1962.csv","EASE-MM_S1676.csv","HotMuSiC_S1626.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","Saraboji_S2204.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18772
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,772
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
7,177
ProTherm
7.5
DSC
Thermal
Sodium cacodylate
50 mM
55
1CSP_A:V20K
null
null
2.32
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":55.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":...
[{"datasets":[],"id":25120,"numValue":2.32,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":25121,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18773
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,773
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,764
MegaScale
null
null
null
null
4.967775
null
null
null
null
null
null
null
1.34713
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365176,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365177,"numValue":1.3471295892366075,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365178,"numValue":4.96777507706777,"references":[],"strValue":null,"type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18774
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,774
train
mutant
1,154
358
1,300
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20K
V20K
1
1
0
0
20
V
K
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,458
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.173608
0.060293
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121598,"numValue":-0.173608016676733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121599,"numValue":0.0602927714346857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18775
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,775
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,084
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:V20Q
38.1
null
null
null
null
null
28.44
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:V20Q","ty...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7800,"numValue":38.1,"references":[],"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18776
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,776
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,085
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:V20Q
27.5
null
null
null
null
null
17.93
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|HotMuSiC_S1626.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:V20Q","ty...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7803,"numValue":27.5,"references":[],"strValue":null,"type"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18778
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,778
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,130
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.05 M
1CSP_A:V20Q
30.1
null
null
null
null
null
20.08
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S1810.csv|M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7938,"numValue":30.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7939,"numValue":20.08,"references":[],"strValue":null,"type":"DHVH"},{"...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18779
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,779
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,175
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:V20Q
40.4
null
null
null
null
null
30.35
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S2760.csv|PON-TStab_dataset.csv|SVM-WIN31_SVM-3D12_S499.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S2760.csv","PON-TStab_dataset.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":8073,"numValue":40.4,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S2760.csv","PON-TStab_dataset.csv","STRUM_Q3421.csv"],"id":8074,"numValue":30.35,"references":[],"strValue":null,"type":"DHVH"},{"datase...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18780
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,780
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,176
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:V20Q
31.4
null
null
null
null
null
21.27
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
EASE-MM_S1676.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|SVM-WIN31_SVM-3D12_S499.csv|STRUM_Q3421.csv|AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["EASE-MM_S1676.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":8076,"numValue":31.4,"references":[],"strValue":null,"type":"TM"},{"datasets":["EASE-MM_S1676.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","STRUM_Q3421.csv"],"id":8077,"numValue":21.27,"references":[]...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18781
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,781
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,221
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.2 M
1CSP_A:V20Q
41.7
null
null
null
null
null
31.55
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|M47andM8_S1810.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8211,"numValue":41.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1925.csv","I_...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18782
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,782
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,222
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.2 M
1CSP_A:V20Q
33.2
null
null
null
null
null
22.71
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8214,"numValue":33.2,"references":[],"strValue":null,"type":"TM"},{"datasets":["AU...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18783
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,783
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,267
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.5 M
1CSP_A:V20Q
44.8
null
null
null
null
null
33.94
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1962.csv|Saraboji_S2204.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
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fireprotdb:18784
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,784
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,268
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.5 M
1CSP_A:V20Q
37.7
null
null
null
null
null
26.53
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
PoPMuSiC-2.0_S2648.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["PoPMuSiC-2.0_S2648.csv"],"id":8352,"numValue":37.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["PoPMuSiC-2.0_S2648.csv"],"id":8353,"numValue":26.53,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["PoPMuSiC-2.0_S2648.csv"],"id":8354,"numValue":null,"references":[],"strValue":"Unk...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18785
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,785
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,313
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:V20Q
49.4
null
null
null
null
null
38
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
Broom_S605.csv|EASE-MM_S238.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["Broom_S605.csv","EASE-MM_S238.csv"],"id":8487,"numValue":49.4,"references":[],"strValue":null,"type":"TM"},{"datasets":["Broom_S605.csv"],"id":8488,"numValue":38.0,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["Broom_S605.csv","STRUM_Q3421.csv"],"id":8489,"numValue":null,"references":[],"st...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18786
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,786
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
2,314
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:V20Q
42.1
null
null
null
null
null
30.11
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
Broom_S605.csv|STRUM_Q3421.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["Broom_S605.csv","STRUM_Q3421.csv"],"id":8490,"numValue":42.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["Broom_S605.csv","STRUM_Q3421.csv"],"id":8491,"numValue":30.11,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["Broom_S605.csv"],"id":8492,"numValue":null,"references":[],"st...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18788
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,788
train
mutant
1,169
358
1,315
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Q
V20Q
1
1
0
0
20
V
Q
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,463
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.04183
0.051342
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121608,"numValue":-0.0418298355738281,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121609,"numValue":0.0513415889792837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18790
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,790
train
mutant
7,842
358
8,554
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20I|E43N|A46K|S48K|E66L
V20I|E43N|A46K|S48K|E66L
5
5
0
0
20
V
I
2
CONSERVATION
1CSP
247
null
20|43|46|48|66
A
L|T|E
false
false
50.640868
39.414371
16,555
ProTherm
7
CD
Thermal
Sodium cacodylate/HCl
0.1M
null
NaCl
0-2M
1CSP_A:V20I 1CSP_A:E43N 1CSP_A:A46K 1CSP_A:S48K 1CSP_A:E66L
69.3
15.5
null
-1.37
51.12
null
null
null
null
null
null
null
null
null
null
null
Unknown
2.0
TM|DTM|DH|DDG|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
186
ARTICLE
Stabilization of the cold shock protein CspB from Bacillus subtilis by evolutionary optimization of Coulombic interactions.
2,005
10.1016/j.jmb.2005.02.014
15784264
J Mol Biol;347;1063-76
3
Wunderlich Michael|Martin Andreas|Schmid Franz X
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":...
[{"datasets":[],"id":60756,"numValue":69.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":60757,"numValue":15.5,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":60758,"numValue":51.12,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":60759,"numValue":-1.37,"references":...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20851,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20854,"numValue":2.0,"position":46,"positionArray":null,"positionRang...
fireprotdb:18791
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,791
train
mutant
7,842
358
8,554
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20I|E43N|A46K|S48K|E66L
V20I|E43N|A46K|S48K|E66L
5
5
0
0
20
V
I
2
CONSERVATION
1CSP
247
null
20|43|46|48|66
A
L|T|E
false
false
50.640868
39.414371
16,590
ProTherm
7
CD
Thermal
Sodium cacodylate/HCl
0.1M
null
NaCl
2M
1CSP_A:V20I 1CSP_A:E43N 1CSP_A:A46K 1CSP_A:S48K 1CSP_A:E66L
69.3
31.8
null
-1.25
51.12
null
null
null
null
null
null
null
null
null
null
null
Unknown
2.0
TM|DTM|DH|DDG|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
186
ARTICLE
Stabilization of the cold shock protein CspB from Bacillus subtilis by evolutionary optimization of Coulombic interactions.
2,005
10.1016/j.jmb.2005.02.014
15784264
J Mol Biol;347;1063-76
3
Wunderlich Michael|Martin Andreas|Schmid Franz X
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":...
[{"datasets":[],"id":60966,"numValue":69.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":60967,"numValue":31.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":60968,"numValue":51.12,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":60969,"numValue":-1.25,"references":...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20851,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20854,"numValue":2.0,"position":46,"positionArray":null,"positionRang...
fireprotdb:18793
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,793
train
mutant
476,135
358
477,487
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20E
V20E
1
1
0
0
20
V
E
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,453
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.505572
0.063471
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121588,"numValue":-0.505572373944832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121589,"numValue":0.0634713274046543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18794
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,794
train
mutant
476,136
358
477,488
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20N
V20N
1
1
0
0
20
V
N
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,760
MegaScale
null
null
null
null
4.820461
null
null
null
null
null
null
1.727033
1.33103
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365164,"numValue":1.7270327599405508,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365165,"numValue":1.3310299372581504,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365166,"numValue":4.820460797351539,"references":[],"strValue":null,"ty...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18797
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,797
train
mutant
476,137
358
477,489
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20H
V20H
1
1
0
0
20
V
H
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,456
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.115434
0.060987
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121594,"numValue":-0.115434251887875,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121595,"numValue":0.0609868379449768,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18798
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,798
train
mutant
476,138
358
477,490
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20D
V20D
1
1
0
0
20
V
D
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,762
MegaScale
null
null
null
null
2.852328
null
null
null
null
null
null
1.076947
0.021677
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365170,"numValue":1.076947334868799,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365171,"numValue":0.0216773724038857,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365172,"numValue":2.852328093917519,"references":[],"strValue":null,"typ...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18799
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,799
train
mutant
476,138
358
477,490
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20D
V20D
1
1
0
0
20
V
D
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,452
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.650692
0.0754
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121586,"numValue":-0.650691892185637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121587,"numValue":0.0753995068545815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18802
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,802
train
mutant
476,140
358
477,492
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20T
V20T
1
1
0
0
20
V
T
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,765
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.239492
1.476043
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365179,"numValue":2.239491846501406,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365180,"numValue":1.4760428641934116,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365181,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18803
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,803
train
mutant
476,140
358
477,492
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20T
V20T
1
1
0
0
20
V
T
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,466
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.045597
0.046297
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121614,"numValue":-0.0455970293757088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121615,"numValue":0.0462973581863446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18804
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,804
train
mutant
476,141
358
477,493
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20S
V20S
1
1
0
0
20
V
S
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,766
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.478495
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365182,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365183,"numValue":1.4784947875103756,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365184,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18805
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,805
train
mutant
476,141
358
477,493
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20S
V20S
1
1
0
0
20
V
S
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,465
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.091044
0.032497
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121612,"numValue":-0.0910444014268231,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121613,"numValue":0.0324970944091765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18806
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,806
train
mutant
476,142
358
477,494
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20A
V20A
1
1
0
0
20
V
A
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,767
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.485273
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365185,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365186,"numValue":1.4852727198179,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365187,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18807
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,807
train
mutant
476,142
358
477,494
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20A
V20A
1
1
0
0
20
V
A
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,450
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.053051
0.040291
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121582,"numValue":-0.0530510681699541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121583,"numValue":0.0402913521435008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18808
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,808
train
mutant
476,143
358
477,495
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20G
V20G
1
1
0
0
20
V
G
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,768
MegaScale
null
null
null
null
4.164702
null
null
null
null
null
null
1.898466
0.881488
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365188,"numValue":1.898465545237062,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365189,"numValue":0.8814880680102011,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365190,"numValue":4.164701650323471,"references":[],"strValue":null,"typ...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18809
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,809
train
mutant
476,143
358
477,495
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20G
V20G
1
1
0
0
20
V
G
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,455
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.352888
0.048273
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121592,"numValue":-0.352887677945779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121593,"numValue":0.0482732703492714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18810
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,810
train
mutant
476,144
358
477,496
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20M
V20M
1
1
0
0
20
V
M
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,769
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.648917
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365191,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365192,"numValue":1.6489172266416856,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365193,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18811
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,811
train
mutant
476,144
358
477,496
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20M
V20M
1
1
0
0
20
V
M
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,460
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.037755
0.045697
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121602,"numValue":-0.0377553535767762,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121603,"numValue":0.0456970789772983,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18812
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,812
train
mutant
476,145
358
477,497
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20L
V20L
1
1
0
0
20
V
L
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,770
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.192123
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365194,"numValue":2.192123285946174,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365195,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365196,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18813
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,813
train
mutant
476,145
358
477,497
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20L
V20L
1
1
0
0
20
V
L
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,459
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.017301
0.030939
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121600,"numValue":-0.0173007547329281,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121601,"numValue":0.0309394928689818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18814
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,814
train
mutant
476,146
358
477,498
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20I
V20I
1
1
0
0
20
V
I
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,771
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.612346
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365197,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365198,"numValue":1.6123456629855064,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365199,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18815
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,815
train
mutant
476,146
358
477,498
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20I
V20I
1
1
0
0
20
V
I
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,457
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
0.015562
0.049513
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121596,"numValue":0.0155619083590548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121597,"numValue":0.0495129604776473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18816
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,816
train
mutant
476,147
358
477,499
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20W
V20W
1
1
0
0
20
V
W
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,772
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
1.593994
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365200,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365201,"numValue":1.593994349866129,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365202,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18817
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,817
train
mutant
476,147
358
477,499
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20W
V20W
1
1
0
0
20
V
W
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,065,406
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.175641
0.052657
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123494,"numValue":-0.175641270902267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123495,"numValue":0.0526568867240644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18818
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,818
train
mutant
476,148
358
477,500
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Y
V20Y
1
1
0
0
20
V
Y
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,773
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.141402
1.412874
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365203,"numValue":2.1414021776575014,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365204,"numValue":1.4128742453765168,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365205,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18819
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,819
train
mutant
476,148
358
477,500
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20Y
V20Y
1
1
0
0
20
V
Y
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,065,407
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.084763
0.068541
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123496,"numValue":-0.0847630872416946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123497,"numValue":0.0685408466053517,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18820
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,820
train
mutant
476,149
358
477,501
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20F
V20F
1
1
0
0
20
V
F
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,774
MegaScale
null
null
null
null
4.959982
null
null
null
null
null
null
2.143306
1.335671
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365206,"numValue":2.1433055195398745,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365207,"numValue":1.3356714015819833,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365208,"numValue":4.959981943340436,"references":[],"strValue":null,"ty...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18821
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,821
train
mutant
476,149
358
477,501
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20F
V20F
1
1
0
0
20
V
F
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,454
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.23936
0.045022
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121590,"numValue":-0.23935971689741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121591,"numValue":0.0450220508414146,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18822
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,822
train
mutant
476,150
358
477,502
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20P
V20P
1
1
0
0
20
V
P
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,775
MegaScale
null
null
null
null
3.601781
null
null
null
null
null
null
1.498947
0.575629
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365209,"numValue":1.4989474678089965,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365210,"numValue":0.5756292913735408,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365211,"numValue":3.6017810819438907,"references":[],"strValue":null,"t...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18823
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,823
train
mutant
476,150
358
477,502
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20P
V20P
1
1
0
0
20
V
P
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,462
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.426503
0.044546
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121606,"numValue":-0.426503134554263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121607,"numValue":0.0445462386851549,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18824
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,824
train
mutant
476,151
358
477,503
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20C
V20C
1
1
0
0
20
V
C
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,776
MegaScale
null
null
null
null
4.572299
null
null
null
null
null
null
1.975153
1.063286
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365212,"numValue":1.975152650994584,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365213,"numValue":1.0632860399477118,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365214,"numValue":4.572299187258329,"references":[],"strValue":null,"typ...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18825
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,825
train
mutant
476,151
358
477,503
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
V20C
V20C
1
1
0
0
20
V
C
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
5,064,451
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.032362
0.075626
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12121584,"numValue":-0.0323615563944679,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12121585,"numValue":0.0756263235702987,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18826
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,826
train
mutant
476,152
358
477,504
67
68
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
insG20
insG20
1
0
0
1
20
-
G
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,777
MegaScale
null
null
null
null
4.451393
null
null
null
null
null
null
1.725244
1.052394
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365215,"numValue":1.725243811818303,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365216,"numValue":1.0523935912129403,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365217,"numValue":4.451393436296849,"references":[],"strValue":null,"typ...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18827
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,827
train
mutant
476,153
358
477,505
67
68
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
insA20
insA20
1
0
0
1
20
-
A
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,778
MegaScale
null
null
null
null
3.928676
null
null
null
null
null
null
1.570728
0.724301
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
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fireprotdb:18828
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,828
train
mutant
476,154
358
477,506
67
66
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
delV20
delV20
1
0
1
0
20
V
-
2
CONSERVATION
1CSP
247
null
20
A
L
false
false
19.518262
45.652857
501,779
MegaScale
null
null
null
null
2.158111
null
null
null
null
null
null
0.476527
-0.483499
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365221,"numValue":0.4765269407295124,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365222,"numValue":-0.4834993316215542,"references":[],"strValue":null,"type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365223,"numValue":2.158110627240473,"references":[],"strValue":null,"t...
[{"id":20828,"numValue":2.0,"position":20,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18830
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,830
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,088
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:E21K
53.8
null
null
null
null
null
42.78
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|M47andM8_S1810.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:E21K","ty...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","STRUM_Q3421.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":7812,"numValue":53.8,"references":[],"strValue":null,"type":"TM"}...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18831
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,831
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,133
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.05 M
1CSP_A:E21K
54.3
null
null
null
null
null
43.26
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S1810.csv|M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S1810.csv","M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7947,"numValue":54.3,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7948,"numValue":43.26,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["M47andM8_...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18832
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,832
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,179
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:E21K
54.6
null
null
null
null
null
43.5
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":8085,"numValue":54.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":8086,"numValue":43.5,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":8087,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18833
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,833
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,225
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.2 M
1CSP_A:E21K
56.1
null
null
null
null
null
44.69
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|PON-TStab_dataset.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8223,"numValue":56.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AU...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18835
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,835
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,317
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:E21K
62.1
null
null
null
null
null
49.71
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|AUTOMUTE_S1962.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PoPMuSiC-2.0_S2648.csv|Saraboji_S2204.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv|EASE-MM_S1676.csv|PON-TStab_dataset.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","AUTOMUTE_S1962.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S2204.csv","STRUM_Q3421.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":8499,"numValue":62...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18836
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,836
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
7,225
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
55
NaCl
0.2 M
1CSP_A:E21K
null
null
0.14
0.19
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|DDG|REVERSIBILITY
potapov_with_uniprot_mapping.csv
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":55.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"...
[{"datasets":[],"id":25262,"numValue":0.14,"references":[],"strValue":null,"type":"DG"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":25263,"numValue":0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":25264,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18837
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,837
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
7,249
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
55
NaCl
0.5 M
1CSP_A:E21K
null
null
0.45
0.17
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|DDG|REVERSIBILITY
khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":55.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"...
[{"datasets":[],"id":25334,"numValue":0.45,"references":[],"strValue":null,"type":"DG"},{"datasets":["khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":25335,"numValue":0.17,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":25336,"numValue":null,"references":[],"strValue":"Unknown"...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18838
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,838
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
7,281
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
55
NaCl
1.0 M
1CSP_A:E21K
null
null
0.98
0.12
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|DDG|REVERSIBILITY
khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":55.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"...
[{"datasets":[],"id":25430,"numValue":0.98,"references":[],"strValue":null,"type":"DG"},{"datasets":["khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":25431,"numValue":0.12,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":25432,"numValue":null,"references":[],"strValue":"Unknown"...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18839
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,839
train
mutant
1,170
358
1,316
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21K
E21K
1
1
0
0
21
E
K
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
501,785
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.205494
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365239,"numValue":2.2054939117414785,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365240,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365241,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18841
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,841
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,089
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
1CSP_A:E21Q
51.9
null
null
null
null
null
34.42
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1CSP_A:E21Q","ty...
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[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18842
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,842
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,134
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.05 M
1CSP_A:E21Q
52.5
null
null
null
null
null
34.89
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
M47andM8_S2760.csv|SVM-WIN31_SVM-3D12_S499.csv|M47andM8_S1810.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7950,"numValue":52.5,"references":[],"strValue":null,"type":"TM"},{"datasets":["M47andM8_S2760.csv","SVM-WIN31_SVM-3D12_S499.csv"],"id":7951,"numValue":34.89,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["M47andM8_S1810.csv","M47andM8_...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18843
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,843
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,180
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.1 M
1CSP_A:E21Q
53.3
null
null
null
null
null
35.61
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":8088,"numValue":53.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":8089,"numValue":35.61,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.cs...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18845
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,845
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,272
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
0.5 M
1CSP_A:E21Q
57.6
null
null
null
null
null
39.2
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1962.csv|Saraboji_S2204.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":8364,"numValue":57.6,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":8365,"numValue":39.2,"references":[],"strValue":null,"type":"DHVH"},{"datasets":["AUTOMUTE_S1962.csv","Saraboji_S2204.csv"],"id":83...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18846
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,846
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
2,318
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
null
NaCl
1.0 M
1CSP_A:E21Q
61.5
null
null
null
null
null
42.54
null
null
null
null
null
null
null
null
null
Unknown
TM|DHVH|REVERSIBILITY
AUTOMUTE_S1925.csv|AUTOMUTE_S1962.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S1810.csv|M47andM8_S2760.csv|PON-TStab_dataset.csv|PoPMuSiC-2.0_S2648.csv|Saraboji_S2204.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":["AUTOMUTE_S1925.csv","AUTOMUTE_S1962.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S1810.csv","M47andM8_S2760.csv","PON-TStab_dataset.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S2204.csv","STRUM_Q3421.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_...
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18847
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,847
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
7,250
ProTherm
7.5
CD
Thermal
Sodium cacodylate
50 mM
55
NaCl
0.5 M
1CSP_A:E21Q
null
null
0.31
0.31
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|DDG|REVERSIBILITY
khan_protherm_data_mapped.csv
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
218
ARTICLE
Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins.
2,007
10.1016/j.jmb.2006.11.061
17188709
J Mol Biol;366;842-56
2
Makhatadze George I|Gribenko Alexey V
[{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":55.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"...
[{"datasets":[],"id":25337,"numValue":0.31,"references":[],"strValue":null,"type":"DG"},{"datasets":["khan_protherm_data_mapped.csv"],"id":25338,"numValue":0.31,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":25339,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18849
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,849
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
501,780
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.233642
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365224,"numValue":2.233641569973837,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365225,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365226,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18850
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,850
train
mutant
1,171
358
1,317
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21Q
E21Q
1
1
0
0
21
E
Q
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
5,065,399
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
0.048115
0.060314
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123480,"numValue":0.0481148298571025,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123481,"numValue":0.0603142386738693,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18851
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,851
train
mutant
476,155
358
477,507
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21N
E21N
1
1
0
0
21
E
N
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
501,781
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365227,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365228,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365229,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18852
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,852
train
mutant
476,155
358
477,507
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21N
E21N
1
1
0
0
21
E
N
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
5,065,397
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
0.021629
0.074753
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123476,"numValue":0.0216285501523469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123477,"numValue":0.0747533429551544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18853
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,853
train
mutant
476,156
358
477,508
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21H
E21H
1
1
0
0
21
E
H
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
501,782
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
2.22902
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365230,"numValue":2.229020319500372,"references":[],"strValue":null,"type":"TRYPSIN_ML"},{"datasets":[],"id":2365231,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365232,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18854
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,854
train
mutant
476,156
358
477,508
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21H
E21H
1
1
0
0
21
E
H
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
5,065,392
Domainome FITNESS
null
null
null
null
null
null
null
null
null
null
null
null
null
null
-0.071902
0.070778
null
null
DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD
1910
ARTICLE
Site-saturation mutagenesis of 500 human protein domains.
2,025
10.1038/s41586-024-08370-4
39779847
Nature;637;885-894
1
Beltran Antoni
[{"datasets":[],"id":12123466,"numValue":-0.0719017575719398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12123467,"numValue":0.0707780396031309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:18855
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
18,855
train
mutant
476,157
358
477,509
67
67
36
Cold shock protein CspB
Bacillus subtilis (strain 168)
1
36|1483
Cold shock protein CspB|1CSQ
Bacillus subtilis (strain 168)
1
P32081
IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340
1CSQ
E21D
E21D
1
1
0
0
21
E
D
4
CONSERVATION
1CSP
247
null
21
A
T
false
false
100.190992
59.088
501,783
MegaScale
null
null
null
null
null
>5
null
null
null
null
null
null
null
null
null
null
null
null
null
TRYPSIN_ML|CHYMOTRYPSIN_ML|DG
1909
ARTICLE
Mega-scale experimental analysis of protein folding stability in biology and design.
2,023
10.1038/s41586-023-06328-6
37468638
Nature;620;434-444
1
Tsuboyama Kotaro
[{"datasets":[],"id":2365233,"numValue":null,"references":[],"strValue":">2.25","type":"TRYPSIN_ML"},{"datasets":[],"id":2365234,"numValue":null,"references":[],"strValue":">1.75","type":"CHYMOTRYPSIN_ML"},{"datasets":[],"id":2365235,"numValue":null,"references":[],"strValue":">5","type":"DG"}]
[{"id":20829,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]