row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5464493 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,493 | train | mutant | 5,058,226 | 5,064,797 | 5,064,894 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244P | S244P | 1 | 1 | 0 | 0 | 244 | S | P | 7 | CONSERVATION | null | false | false | null | null | 5,456,703 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.421132 | 0.111004 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906088,"numValue":-0.421132020652823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906089,"numValue":0.111004091540494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464494 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,494 | train | mutant | 5,058,227 | 5,064,797 | 5,064,895 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244Q | S244Q | 1 | 1 | 0 | 0 | 244 | S | Q | 7 | CONSERVATION | null | false | false | null | null | 5,456,704 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.452651 | 0.10995 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906090,"numValue":-0.452651195055075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906091,"numValue":0.109950447278161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464495 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,495 | train | mutant | 5,058,228 | 5,064,797 | 5,064,896 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244R | S244R | 1 | 1 | 0 | 0 | 244 | S | R | 7 | CONSERVATION | null | false | false | null | null | 5,456,705 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.475506 | 0.063497 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906092,"numValue":-0.475505586976996,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906093,"numValue":0.0634966582029163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464496 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,496 | train | mutant | 5,059,226 | 5,064,797 | 5,065,894 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244T | S244T | 1 | 1 | 0 | 0 | 244 | S | T | 7 | CONSERVATION | null | false | false | null | null | 5,457,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161745 | 0.065358 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908094,"numValue":-0.161745468314348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908095,"numValue":0.0653575955471075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464497 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,497 | train | mutant | 5,059,227 | 5,064,797 | 5,065,895 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244V | S244V | 1 | 1 | 0 | 0 | 244 | S | V | 7 | CONSERVATION | null | false | false | null | null | 5,457,707 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.745502 | 0.087577 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908096,"numValue":-0.745501856023541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908097,"numValue":0.0875765421174475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464499 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,499 | train | mutant | 5,059,229 | 5,064,797 | 5,065,897 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S244Y | S244Y | 1 | 1 | 0 | 0 | 244 | S | Y | 7 | CONSERVATION | null | false | false | null | null | 5,457,709 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.342981 | 0.071399 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908100,"numValue":-0.342981062617703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908101,"numValue":0.0713989804135518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463180,"numValue":7.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464500 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,500 | train | mutant | 5,058,229 | 5,064,797 | 5,064,897 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delY245 | delY245 | 1 | 0 | 1 | 0 | 245 | Y | - | 4 | CONSERVATION | null | false | false | null | null | 5,456,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.695466 | 0.33799 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906094,"numValue":-0.695466388707784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906095,"numValue":0.337989643674053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464501 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,501 | train | mutant | 5,058,230 | 5,064,797 | 5,064,898 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245A | Y245A | 1 | 1 | 0 | 0 | 245 | Y | A | 4 | CONSERVATION | null | false | false | null | null | 5,456,707 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.207977 | 0.076267 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906096,"numValue":-0.207977415463556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906097,"numValue":0.0762670725354971,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464502 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,502 | train | mutant | 5,058,231 | 5,064,797 | 5,064,899 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245C | Y245C | 1 | 1 | 0 | 0 | 245 | Y | C | 4 | CONSERVATION | null | false | false | null | null | 5,456,708 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.247012 | 0.073008 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906098,"numValue":-0.247011720494755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906099,"numValue":0.0730078197815398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464503 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,503 | train | mutant | 5,058,232 | 5,064,797 | 5,064,900 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245D | Y245D | 1 | 1 | 0 | 0 | 245 | Y | D | 4 | CONSERVATION | null | false | false | null | null | 5,456,709 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.312695 | 0.083612 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906100,"numValue":-0.312695449138564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906101,"numValue":0.0836117311526706,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,505 | train | mutant | 5,058,234 | 5,064,797 | 5,064,902 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245F | Y245F | 1 | 1 | 0 | 0 | 245 | Y | F | 4 | CONSERVATION | null | false | false | null | null | 5,456,711 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.039312 | 0.068031 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906104,"numValue":0.0393123757921636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906105,"numValue":0.0680311044391799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,506 | train | mutant | 5,058,235 | 5,064,797 | 5,064,903 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245G | Y245G | 1 | 1 | 0 | 0 | 245 | Y | G | 4 | CONSERVATION | null | false | false | null | null | 5,456,712 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.099151 | 0.05235 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906106,"numValue":-0.0991512521778825,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906107,"numValue":0.0523496502434506,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,508 | train | mutant | 5,058,237 | 5,064,797 | 5,064,905 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245I | Y245I | 1 | 1 | 0 | 0 | 245 | Y | I | 4 | CONSERVATION | null | false | false | null | null | 5,456,714 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.191348 | 0.094769 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906110,"numValue":-0.19134780827102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906111,"numValue":0.0947686228202365,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,511 | train | mutant | 5,058,240 | 5,064,797 | 5,064,908 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245M | Y245M | 1 | 1 | 0 | 0 | 245 | Y | M | 4 | CONSERVATION | null | false | false | null | null | 5,456,717 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.054585 | 0.070733 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906116,"numValue":-0.0545848025338179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906117,"numValue":0.0707326838428065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,512 | train | mutant | 5,058,241 | 5,064,797 | 5,064,909 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245N | Y245N | 1 | 1 | 0 | 0 | 245 | Y | N | 4 | CONSERVATION | null | false | false | null | null | 5,456,718 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.256415 | 0.070919 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906118,"numValue":-0.256415390649745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906119,"numValue":0.0709194010411423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,513 | train | mutant | 5,058,242 | 5,064,797 | 5,064,910 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245P | Y245P | 1 | 1 | 0 | 0 | 245 | Y | P | 4 | CONSERVATION | null | false | false | null | null | 5,456,719 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.657994 | 0.138411 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906120,"numValue":-0.657993572960259,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906121,"numValue":0.138410745741119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464514 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,514 | train | mutant | 5,058,243 | 5,064,797 | 5,064,911 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245Q | Y245Q | 1 | 1 | 0 | 0 | 245 | Y | Q | 4 | CONSERVATION | null | false | false | null | null | 5,456,720 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.223234 | 0.103325 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906122,"numValue":-0.223234231215121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906123,"numValue":0.10332455767217,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,515 | train | mutant | 5,058,244 | 5,064,797 | 5,064,912 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245R | Y245R | 1 | 1 | 0 | 0 | 245 | Y | R | 4 | CONSERVATION | null | false | false | null | null | 5,456,721 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.369784 | 0.055151 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906124,"numValue":-0.369784156914003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906125,"numValue":0.0551510424149601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464516 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,516 | train | mutant | 5,058,245 | 5,064,797 | 5,064,913 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245S | Y245S | 1 | 1 | 0 | 0 | 245 | Y | S | 4 | CONSERVATION | null | false | false | null | null | 5,456,722 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218962 | 0.061001 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906126,"numValue":-0.218961698365079,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906127,"numValue":0.0610006072406831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464517 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,517 | train | mutant | 5,058,246 | 5,064,797 | 5,064,914 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245T | Y245T | 1 | 1 | 0 | 0 | 245 | Y | T | 4 | CONSERVATION | null | false | false | null | null | 5,456,723 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.200747 | 0.079384 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906128,"numValue":-0.200746599991608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906129,"numValue":0.0793842457659049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,518 | train | mutant | 5,058,247 | 5,064,797 | 5,064,915 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245V | Y245V | 1 | 1 | 0 | 0 | 245 | Y | V | 4 | CONSERVATION | null | false | false | null | null | 5,456,724 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.193171 | 0.052009 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906130,"numValue":-0.193171367050816,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906131,"numValue":0.0520086476786893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464519 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,519 | train | mutant | 5,058,248 | 5,064,797 | 5,064,916 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | Y245W | Y245W | 1 | 1 | 0 | 0 | 245 | Y | W | 4 | CONSERVATION | null | false | false | null | null | 5,456,725 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.154924 | 0.06721 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906132,"numValue":-0.154924441332242,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906133,"numValue":0.0672103468783707,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463181,"numValue":4.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,520 | train | mutant | 5,058,249 | 5,064,797 | 5,064,917 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delC246 | delC246 | 1 | 0 | 1 | 0 | 246 | C | - | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,456,726 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.402468 | 0.313504 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906134,"numValue":-1.40246812826724,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906135,"numValue":0.313503610581745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,521 | train | mutant | 5,058,250 | 5,064,797 | 5,064,918 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246A | C246A | 1 | 1 | 0 | 0 | 246 | C | A | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,456,727 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.882632 | 0.11317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906136,"numValue":-0.882632403008656,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906137,"numValue":0.113169628571933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464522 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,522 | train | mutant | 5,059,208 | 5,064,797 | 5,065,876 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246D | C246D | 1 | 1 | 0 | 0 | 246 | C | D | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,688 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.939481 | 0.292712 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908058,"numValue":-0.939481482086227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908059,"numValue":0.292712113431425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,523 | train | mutant | 5,059,209 | 5,064,797 | 5,065,877 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246E | C246E | 1 | 1 | 0 | 0 | 246 | C | E | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,689 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.99685 | 0.176326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908060,"numValue":-0.996849821721639,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908061,"numValue":0.17632632819505,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464524 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,524 | train | mutant | 5,059,210 | 5,064,797 | 5,065,878 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246F | C246F | 1 | 1 | 0 | 0 | 246 | C | F | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,690 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.230916 | 0.165083 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908062,"numValue":-1.23091628479481,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908063,"numValue":0.16508270772067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,525 | train | mutant | 5,059,211 | 5,064,797 | 5,065,879 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246G | C246G | 1 | 1 | 0 | 0 | 246 | C | G | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,691 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.762231 | 0.067426 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908064,"numValue":-0.762231275983959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908065,"numValue":0.0674263054125173,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464526 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,526 | train | mutant | 5,059,212 | 5,064,797 | 5,065,880 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246H | C246H | 1 | 1 | 0 | 0 | 246 | C | H | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,692 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.549015 | 0.148148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908066,"numValue":-0.549014714677776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908067,"numValue":0.14814790567189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464527 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,527 | train | mutant | 5,059,213 | 5,064,797 | 5,065,881 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246I | C246I | 1 | 1 | 0 | 0 | 246 | C | I | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,693 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.10485 | 0.207303 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908068,"numValue":-1.10484996849422,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908069,"numValue":0.207303313397766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,528 | train | mutant | 5,059,214 | 5,064,797 | 5,065,882 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246K | C246K | 1 | 1 | 0 | 0 | 246 | C | K | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,694 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.943439 | 0.135219 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908070,"numValue":-0.943439453485971,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908071,"numValue":0.135219176386067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,529 | train | mutant | 5,059,215 | 5,064,797 | 5,065,883 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246L | C246L | 1 | 1 | 0 | 0 | 246 | C | L | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,695 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.216813 | 0.110891 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908072,"numValue":-1.21681325780701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908073,"numValue":0.110891009431036,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,530 | train | mutant | 5,059,216 | 5,064,797 | 5,065,884 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246M | C246M | 1 | 1 | 0 | 0 | 246 | C | M | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,696 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.114518 | 0.143278 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908074,"numValue":-1.11451814736253,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908075,"numValue":0.143277862176184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,531 | train | mutant | 5,059,217 | 5,064,797 | 5,065,885 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246N | C246N | 1 | 1 | 0 | 0 | 246 | C | N | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,697 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.746382 | 0.224133 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908076,"numValue":-0.746382023158509,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908077,"numValue":0.224133229106883,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464532 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,532 | train | mutant | 5,059,218 | 5,064,797 | 5,065,886 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246P | C246P | 1 | 1 | 0 | 0 | 246 | C | P | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,698 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.287083 | 0.196333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908078,"numValue":-1.28708292944063,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908079,"numValue":0.196332787681258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,533 | train | mutant | 5,059,219 | 5,064,797 | 5,065,887 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246Q | C246Q | 1 | 1 | 0 | 0 | 246 | C | Q | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,699 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.999762 | 0.178592 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908080,"numValue":-0.999761856785406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908081,"numValue":0.178592165837811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,534 | train | mutant | 5,059,220 | 5,064,797 | 5,065,888 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246R | C246R | 1 | 1 | 0 | 0 | 246 | C | R | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,700 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.768114 | 0.072102 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908082,"numValue":-0.768113789755639,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908083,"numValue":0.0721021579483828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,535 | train | mutant | 5,059,221 | 5,064,797 | 5,065,889 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246S | C246S | 1 | 1 | 0 | 0 | 246 | C | S | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,701 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.173292 | 0.131067 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908084,"numValue":-1.17329184686699,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908085,"numValue":0.131067433571841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,536 | train | mutant | 5,059,222 | 5,064,797 | 5,065,890 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246T | C246T | 1 | 1 | 0 | 0 | 246 | C | T | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,702 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.867847 | 0.119918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908086,"numValue":-0.867847234295162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908087,"numValue":0.119917869312748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,537 | train | mutant | 5,059,223 | 5,064,797 | 5,065,891 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246V | C246V | 1 | 1 | 0 | 0 | 246 | C | V | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,703 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.098732 | 0.105365 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908088,"numValue":-1.09873172877219,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908089,"numValue":0.105365206782894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464538 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,538 | train | mutant | 5,059,224 | 5,064,797 | 5,065,892 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | C246W | C246W | 1 | 1 | 0 | 0 | 246 | C | W | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,704 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.272289 | 0.180053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908090,"numValue":-1.27228885270592,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908091,"numValue":0.180053354510162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6092,"numValue":null,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463182,"numValue":9.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464540 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,540 | train | mutant | 5,058,251 | 5,064,797 | 5,064,919 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delH247 | delH247 | 1 | 0 | 1 | 0 | 247 | H | - | 5 | CONSERVATION | null | false | false | null | null | 5,456,728 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.319435 | 0.284489 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906138,"numValue":-1.31943525262708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906139,"numValue":0.284488634127179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,541 | train | mutant | 5,058,252 | 5,064,797 | 5,064,920 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247A | H247A | 1 | 1 | 0 | 0 | 247 | H | A | 5 | CONSERVATION | null | false | false | null | null | 5,456,729 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.106871 | 0.05826 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906140,"numValue":-0.106870886776999,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906141,"numValue":0.0582600979305215,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,542 | train | mutant | 5,058,253 | 5,064,797 | 5,064,921 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247C | H247C | 1 | 1 | 0 | 0 | 247 | H | C | 5 | CONSERVATION | null | false | false | null | null | 5,456,730 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.176292 | 0.117202 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906142,"numValue":-0.176291984016854,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906143,"numValue":0.117201557037224,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,543 | train | mutant | 5,058,254 | 5,064,797 | 5,064,922 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247D | H247D | 1 | 1 | 0 | 0 | 247 | H | D | 5 | CONSERVATION | null | false | false | null | null | 5,456,731 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.473757 | 0.078602 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906144,"numValue":-0.473757156087004,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906145,"numValue":0.0786017546445519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464544 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,544 | train | mutant | 5,058,255 | 5,064,797 | 5,064,923 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247E | H247E | 1 | 1 | 0 | 0 | 247 | H | E | 5 | CONSERVATION | null | false | false | null | null | 5,456,732 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.230235 | 0.092702 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906146,"numValue":-0.230234784583253,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906147,"numValue":0.0927023521720281,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464545 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,545 | train | mutant | 5,058,256 | 5,064,797 | 5,064,924 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247F | H247F | 1 | 1 | 0 | 0 | 247 | H | F | 5 | CONSERVATION | null | false | false | null | null | 5,456,733 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.24289 | 0.111258 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906148,"numValue":-0.242890419111202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906149,"numValue":0.111257867698132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,546 | train | mutant | 5,058,257 | 5,064,797 | 5,064,925 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247G | H247G | 1 | 1 | 0 | 0 | 247 | H | G | 5 | CONSERVATION | null | false | false | null | null | 5,456,734 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.027082 | 0.04783 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906150,"numValue":-0.0270821407441449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906151,"numValue":0.0478299661496901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,547 | train | mutant | 5,059,195 | 5,064,797 | 5,065,863 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247I | H247I | 1 | 1 | 0 | 0 | 247 | H | I | 5 | CONSERVATION | null | false | false | null | null | 5,457,675 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.406005 | 0.187002 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908032,"numValue":-0.406005263962438,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908033,"numValue":0.187001611061495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,548 | train | mutant | 5,059,196 | 5,064,797 | 5,065,864 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247K | H247K | 1 | 1 | 0 | 0 | 247 | H | K | 5 | CONSERVATION | null | false | false | null | null | 5,457,676 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.027484 | 0.067754 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908034,"numValue":-0.0274841237389421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908035,"numValue":0.0677535117647873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464549 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,549 | train | mutant | 5,059,197 | 5,064,797 | 5,065,865 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247L | H247L | 1 | 1 | 0 | 0 | 247 | H | L | 5 | CONSERVATION | null | false | false | null | null | 5,457,677 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.175669 | 0.044704 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908036,"numValue":-0.175669495787046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908037,"numValue":0.0447038848980626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464550 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,550 | train | mutant | 5,059,198 | 5,064,797 | 5,065,866 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247M | H247M | 1 | 1 | 0 | 0 | 247 | H | M | 5 | CONSERVATION | null | false | false | null | null | 5,457,678 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.109441 | 0.05353 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908038,"numValue":-0.109440846020436,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908039,"numValue":0.0535302118552098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464551 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,551 | train | mutant | 5,059,199 | 5,064,797 | 5,065,867 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247N | H247N | 1 | 1 | 0 | 0 | 247 | H | N | 5 | CONSERVATION | null | false | false | null | null | 5,457,679 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.168917 | 0.111288 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908040,"numValue":-0.168916766886581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908041,"numValue":0.111287821285366,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,552 | train | mutant | 5,059,200 | 5,064,797 | 5,065,868 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247P | H247P | 1 | 1 | 0 | 0 | 247 | H | P | 5 | CONSERVATION | null | false | false | null | null | 5,457,680 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.677411 | 0.080585 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908042,"numValue":-0.677411498120104,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908043,"numValue":0.0805854236414507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,553 | train | mutant | 5,059,201 | 5,064,797 | 5,065,869 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247Q | H247Q | 1 | 1 | 0 | 0 | 247 | H | Q | 5 | CONSERVATION | null | false | false | null | null | 5,457,681 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.17227 | 0.083749 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908044,"numValue":-0.17227020269512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908045,"numValue":0.0837486688063594,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,554 | train | mutant | 5,059,202 | 5,064,797 | 5,065,870 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247R | H247R | 1 | 1 | 0 | 0 | 247 | H | R | 5 | CONSERVATION | null | false | false | null | null | 5,457,682 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.061275 | 0.054812 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908046,"numValue":-0.0612750874739267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908047,"numValue":0.0548121473338608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,555 | train | mutant | 5,059,203 | 5,064,797 | 5,065,871 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247S | H247S | 1 | 1 | 0 | 0 | 247 | H | S | 5 | CONSERVATION | null | false | false | null | null | 5,457,683 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.095604 | 0.07268 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908048,"numValue":-0.0956036546801086,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908049,"numValue":0.0726800182602727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,556 | train | mutant | 5,059,204 | 5,064,797 | 5,065,872 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247T | H247T | 1 | 1 | 0 | 0 | 247 | H | T | 5 | CONSERVATION | null | false | false | null | null | 5,457,684 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.076129 | 0.055113 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908050,"numValue":-0.076128944543814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908051,"numValue":0.055112717434291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,557 | train | mutant | 5,059,205 | 5,064,797 | 5,065,873 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247V | H247V | 1 | 1 | 0 | 0 | 247 | H | V | 5 | CONSERVATION | null | false | false | null | null | 5,457,685 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.456598 | 0.062611 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908052,"numValue":-0.45659755578094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908053,"numValue":0.0626105393779773,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,558 | train | mutant | 5,059,206 | 5,064,797 | 5,065,874 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247W | H247W | 1 | 1 | 0 | 0 | 247 | H | W | 5 | CONSERVATION | null | false | false | null | null | 5,457,686 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.584132 | 0.077306 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908054,"numValue":-0.584132319864279,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908055,"numValue":0.0773062766319984,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,559 | train | mutant | 5,059,207 | 5,064,797 | 5,065,875 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H247Y | H247Y | 1 | 1 | 0 | 0 | 247 | H | Y | 5 | CONSERVATION | null | false | false | null | null | 5,457,687 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.165102 | 0.094644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908056,"numValue":-0.165101831183529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908057,"numValue":0.094643773926998,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463183,"numValue":5.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,560 | train | mutant | 5,058,258 | 5,064,797 | 5,064,926 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delS248 | delS248 | 1 | 0 | 1 | 0 | 248 | S | - | 5 | CONSERVATION | null | false | false | null | null | 5,456,735 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.588776 | 0.421297 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906152,"numValue":-1.58877553811321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906153,"numValue":0.421296814166952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,561 | train | mutant | 5,058,259 | 5,064,797 | 5,064,927 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248A | S248A | 1 | 1 | 0 | 0 | 248 | S | A | 5 | CONSERVATION | null | false | false | null | null | 5,456,736 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.050926 | 0.063219 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906154,"numValue":-0.0509259767316583,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906155,"numValue":0.0632188020930659,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,562 | train | mutant | 5,058,260 | 5,064,797 | 5,064,928 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248C | S248C | 1 | 1 | 0 | 0 | 248 | S | C | 5 | CONSERVATION | null | false | false | null | null | 5,456,737 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.086104 | 0.076795 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906156,"numValue":-0.0861043672108218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906157,"numValue":0.076794899624151,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,563 | train | mutant | 5,058,261 | 5,064,797 | 5,064,929 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248D | S248D | 1 | 1 | 0 | 0 | 248 | S | D | 5 | CONSERVATION | null | false | false | null | null | 5,456,738 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130352 | 0.071653 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906158,"numValue":-0.130351767244938,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906159,"numValue":0.0716526297318951,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,564 | train | mutant | 5,058,262 | 5,064,797 | 5,064,930 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248E | S248E | 1 | 1 | 0 | 0 | 248 | S | E | 5 | CONSERVATION | null | false | false | null | null | 5,456,739 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073672 | 0.081851 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906160,"numValue":-0.0736721649785238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906161,"numValue":0.081850518764543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,565 | train | mutant | 5,058,263 | 5,064,797 | 5,064,931 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248F | S248F | 1 | 1 | 0 | 0 | 248 | S | F | 5 | CONSERVATION | null | false | false | null | null | 5,456,740 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.622457 | 0.112803 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906162,"numValue":-0.622456910258548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906163,"numValue":0.112803258148276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,566 | train | mutant | 5,058,264 | 5,064,797 | 5,064,932 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248G | S248G | 1 | 1 | 0 | 0 | 248 | S | G | 5 | CONSERVATION | null | false | false | null | null | 5,456,741 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.110163 | 0.05888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906164,"numValue":-0.110162854312062,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906165,"numValue":0.0588797469115065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,567 | train | mutant | 5,058,265 | 5,064,797 | 5,064,933 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248H | S248H | 1 | 1 | 0 | 0 | 248 | S | H | 5 | CONSERVATION | null | false | false | null | null | 5,456,742 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.081414 | 0.131241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906166,"numValue":-0.0814142403758935,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906167,"numValue":0.131240715561831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,569 | train | mutant | 5,058,267 | 5,064,797 | 5,064,935 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248K | S248K | 1 | 1 | 0 | 0 | 248 | S | K | 5 | CONSERVATION | null | false | false | null | null | 5,456,744 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.04346 | 0.111852 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906170,"numValue":-0.0434600207214916,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906171,"numValue":0.111852353714467,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,570 | train | mutant | 5,058,268 | 5,064,797 | 5,064,936 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248L | S248L | 1 | 1 | 0 | 0 | 248 | S | L | 5 | CONSERVATION | null | false | false | null | null | 5,456,745 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.152964 | 0.055533 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906172,"numValue":-0.152964286389165,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906173,"numValue":0.0555333262916385,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,571 | train | mutant | 5,058,269 | 5,064,797 | 5,064,937 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248M | S248M | 1 | 1 | 0 | 0 | 248 | S | M | 5 | CONSERVATION | null | false | false | null | null | 5,456,746 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.149082 | 0.056534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906174,"numValue":-0.149082028291353,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906175,"numValue":0.0565343907879782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,572 | train | mutant | 5,058,270 | 5,064,797 | 5,064,938 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248N | S248N | 1 | 1 | 0 | 0 | 248 | S | N | 5 | CONSERVATION | null | false | false | null | null | 5,456,747 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003428 | 0.110714 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906176,"numValue":-0.00342758801146307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906177,"numValue":0.110714312536963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,573 | train | mutant | 5,058,271 | 5,064,797 | 5,064,939 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248P | S248P | 1 | 1 | 0 | 0 | 248 | S | P | 5 | CONSERVATION | null | false | false | null | null | 5,456,748 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.678576 | 0.093534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906178,"numValue":-0.678575785274695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906179,"numValue":0.0935343398888328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,574 | train | mutant | 5,058,272 | 5,064,797 | 5,064,940 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248Q | S248Q | 1 | 1 | 0 | 0 | 248 | S | Q | 5 | CONSERVATION | null | false | false | null | null | 5,456,749 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.159583 | 0.097338 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906180,"numValue":-0.159583346186992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906181,"numValue":0.0973382405732652,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,575 | train | mutant | 5,058,273 | 5,064,797 | 5,064,941 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248R | S248R | 1 | 1 | 0 | 0 | 248 | S | R | 5 | CONSERVATION | null | false | false | null | null | 5,456,750 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.041543 | 0.059866 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906182,"numValue":0.0415427960011601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906183,"numValue":0.0598663907557512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,576 | train | mutant | 5,059,191 | 5,064,797 | 5,065,859 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248T | S248T | 1 | 1 | 0 | 0 | 248 | S | T | 5 | CONSERVATION | null | false | false | null | null | 5,457,671 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025932 | 0.052678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908024,"numValue":-0.0259318059119459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908025,"numValue":0.0526779005806827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464577 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,577 | train | mutant | 5,059,192 | 5,064,797 | 5,065,860 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248V | S248V | 1 | 1 | 0 | 0 | 248 | S | V | 5 | CONSERVATION | null | false | false | null | null | 5,457,672 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.087573 | 0.061167 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908026,"numValue":0.0875727759660885,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908027,"numValue":0.0611669423400837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,578 | train | mutant | 5,059,193 | 5,064,797 | 5,065,861 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248W | S248W | 1 | 1 | 0 | 0 | 248 | S | W | 5 | CONSERVATION | null | false | false | null | null | 5,457,673 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.416053 | 0.127046 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908028,"numValue":-0.416053082595985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908029,"numValue":0.127046237662235,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,579 | train | mutant | 5,059,194 | 5,064,797 | 5,065,862 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S248Y | S248Y | 1 | 1 | 0 | 0 | 248 | S | Y | 5 | CONSERVATION | null | false | false | null | null | 5,457,674 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.324292 | 0.074099 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908030,"numValue":-0.324292463401089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908031,"numValue":0.07409932069484,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463184,"numValue":5.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,580 | train | mutant | 5,058,274 | 5,064,797 | 5,064,942 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delE249 | delE249 | 1 | 0 | 1 | 0 | 249 | E | - | 5 | CONSERVATION | null | false | false | null | null | 5,456,751 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.212578 | 0.20241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906184,"numValue":-1.21257763519166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906185,"numValue":0.202410048554301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,581 | train | mutant | 5,058,275 | 5,064,797 | 5,064,943 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249A | E249A | 1 | 1 | 0 | 0 | 249 | E | A | 5 | CONSERVATION | null | false | false | null | null | 5,456,752 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041331 | 0.054546 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906186,"numValue":-0.0413310719480751,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906187,"numValue":0.0545462141176911,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,582 | train | mutant | 5,058,276 | 5,064,797 | 5,064,944 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249C | E249C | 1 | 1 | 0 | 0 | 249 | E | C | 5 | CONSERVATION | null | false | false | null | null | 5,456,753 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.171396 | 0.089644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906188,"numValue":-0.171395987250124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906189,"numValue":0.0896437396681924,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,583 | train | mutant | 5,058,277 | 5,064,797 | 5,064,945 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249D | E249D | 1 | 1 | 0 | 0 | 249 | E | D | 5 | CONSERVATION | null | false | false | null | null | 5,456,754 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.194522 | 0.102423 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906190,"numValue":0.194521717693534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906191,"numValue":0.102422730288453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,584 | train | mutant | 5,059,175 | 5,064,797 | 5,065,843 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249F | E249F | 1 | 1 | 0 | 0 | 249 | E | F | 5 | CONSERVATION | null | false | false | null | null | 5,457,655 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.133185 | 0.102509 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907992,"numValue":-0.133185161946131,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907993,"numValue":0.102508981008696,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464585 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,585 | train | mutant | 5,059,176 | 5,064,797 | 5,065,844 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249G | E249G | 1 | 1 | 0 | 0 | 249 | E | G | 5 | CONSERVATION | null | false | false | null | null | 5,457,656 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.104863 | 0.061707 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907994,"numValue":-0.104862923176774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907995,"numValue":0.0617066825655494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,586 | train | mutant | 5,059,177 | 5,064,797 | 5,065,845 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249H | E249H | 1 | 1 | 0 | 0 | 249 | E | H | 5 | CONSERVATION | null | false | false | null | null | 5,457,657 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.07757 | 0.091366 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907996,"numValue":0.0775700340664245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907997,"numValue":0.0913663441264556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,587 | train | mutant | 5,059,178 | 5,064,797 | 5,065,846 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249I | E249I | 1 | 1 | 0 | 0 | 249 | E | I | 5 | CONSERVATION | null | false | false | null | null | 5,457,658 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01827 | 0.140418 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907998,"numValue":0.0182697368387834,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907999,"numValue":0.140418123929216,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,588 | train | mutant | 5,059,179 | 5,064,797 | 5,065,847 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249K | E249K | 1 | 1 | 0 | 0 | 249 | E | K | 5 | CONSERVATION | null | false | false | null | null | 5,457,659 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.021591 | 0.082811 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908000,"numValue":-0.0215909749802638,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908001,"numValue":0.0828107605217994,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,589 | train | mutant | 5,059,180 | 5,064,797 | 5,065,848 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249L | E249L | 1 | 1 | 0 | 0 | 249 | E | L | 5 | CONSERVATION | null | false | false | null | null | 5,457,660 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.087486 | 0.050116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908002,"numValue":-0.0874859398337173,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908003,"numValue":0.0501163127306812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,590 | train | mutant | 5,059,181 | 5,064,797 | 5,065,849 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249M | E249M | 1 | 1 | 0 | 0 | 249 | E | M | 5 | CONSERVATION | null | false | false | null | null | 5,457,661 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.074426 | 0.07975 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908004,"numValue":0.074426370937209,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908005,"numValue":0.0797499429656136,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464591 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,591 | train | mutant | 5,059,182 | 5,064,797 | 5,065,850 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249N | E249N | 1 | 1 | 0 | 0 | 249 | E | N | 5 | CONSERVATION | null | false | false | null | null | 5,457,662 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.029573 | 0.111015 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908006,"numValue":0.0295730693502551,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908007,"numValue":0.111015409508309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,592 | train | mutant | 5,059,183 | 5,064,797 | 5,065,851 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249P | E249P | 1 | 1 | 0 | 0 | 249 | E | P | 5 | CONSERVATION | null | false | false | null | null | 5,457,663 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.099934 | 0.089551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908008,"numValue":0.0999337530561045,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908009,"numValue":0.089550737194736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,593 | train | mutant | 5,059,184 | 5,064,797 | 5,065,852 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249Q | E249Q | 1 | 1 | 0 | 0 | 249 | E | Q | 5 | CONSERVATION | null | false | false | null | null | 5,457,664 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.078829 | 0.062338 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908010,"numValue":0.0788286701423675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908011,"numValue":0.0623375324319234,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,594 | train | mutant | 5,059,185 | 5,064,797 | 5,065,853 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249R | E249R | 1 | 1 | 0 | 0 | 249 | E | R | 5 | CONSERVATION | null | false | false | null | null | 5,457,665 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.054177 | 0.054183 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908012,"numValue":0.0541769654177371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908013,"numValue":0.0541827414840701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,595 | train | mutant | 5,059,186 | 5,064,797 | 5,065,854 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249S | E249S | 1 | 1 | 0 | 0 | 249 | E | S | 5 | CONSERVATION | null | false | false | null | null | 5,457,666 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.029659 | 0.049435 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908014,"numValue":0.0296589297957458,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908015,"numValue":0.0494347661739925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,596 | train | mutant | 5,059,187 | 5,064,797 | 5,065,855 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249T | E249T | 1 | 1 | 0 | 0 | 249 | E | T | 5 | CONSERVATION | null | false | false | null | null | 5,457,667 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.034338 | 0.04179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908016,"numValue":0.0343383240749877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908017,"numValue":0.0417900448135667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,598 | train | mutant | 5,059,189 | 5,064,797 | 5,065,857 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249W | E249W | 1 | 1 | 0 | 0 | 249 | E | W | 5 | CONSERVATION | null | false | false | null | null | 5,457,669 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103577 | 0.071833 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908020,"numValue":-0.103576967868175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908021,"numValue":0.0718326732319677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,599 | train | mutant | 5,059,190 | 5,064,797 | 5,065,858 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | E249Y | E249Y | 1 | 1 | 0 | 0 | 249 | E | Y | 5 | CONSERVATION | null | false | false | null | null | 5,457,670 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.229563 | 0.090522 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12908022,"numValue":-0.229562536322536,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12908023,"numValue":0.0905216529664658,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463185,"numValue":5.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5464600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,464,600 | train | mutant | 5,058,278 | 5,064,797 | 5,064,946 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delS250 | delS250 | 1 | 0 | 1 | 0 | 250 | S | - | 8 | CONSERVATION | null | false | false | null | null | 5,456,755 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.27953 | 0.234249 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906192,"numValue":-1.27952990313325,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906193,"numValue":0.23424934582207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463186,"numValue":8.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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