row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:10601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,601 | train | mutant | 3,783,564 | 225 | 3,787,509 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179F | M179F | 1 | 1 | 0 | 0 | 179 | M | F | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,184 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.498964 | 0.115606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179050,"numValue":-0.49896404835668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179051,"numValue":0.115606027613977,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,602 | train | mutant | 3,783,564 | 225 | 3,787,509 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179F | M179F | 1 | 1 | 0 | 0 | 179 | M | F | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,138 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.342527 | 0.06999 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180958,"numValue":-0.34252657350623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180959,"numValue":0.069989778660851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10603 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,603 | train | mutant | 3,783,565 | 225 | 3,787,510 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179G | M179G | 1 | 1 | 0 | 0 | 179 | M | G | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,789 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.260909 | 0.058156 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666260,"numValue":0.260909456709179,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666261,"numValue":0.0581561322234174,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,604 | train | mutant | 3,783,565 | 225 | 3,787,510 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179G | M179G | 1 | 1 | 0 | 0 | 179 | M | G | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,185 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.338719 | 0.037922 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179052,"numValue":-0.338719369096885,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179053,"numValue":0.0379216998927187,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10605 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,605 | train | mutant | 3,783,565 | 225 | 3,787,510 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179G | M179G | 1 | 1 | 0 | 0 | 179 | M | G | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,139 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.43218 | 0.036989 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180960,"numValue":-0.432179672180433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180961,"numValue":0.0369893376774571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,606 | train | mutant | 3,783,566 | 225 | 3,787,511 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179H | M179H | 1 | 1 | 0 | 0 | 179 | M | H | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,790 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.272483 | 0.06054 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666262,"numValue":0.272482844179734,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666263,"numValue":0.0605398771918686,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10607 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,607 | train | mutant | 3,783,566 | 225 | 3,787,511 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179H | M179H | 1 | 1 | 0 | 0 | 179 | M | H | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,186 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.456364 | 0.069499 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179054,"numValue":-0.456363781376732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179055,"numValue":0.0694991994619152,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,608 | train | mutant | 3,783,566 | 225 | 3,787,511 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179H | M179H | 1 | 1 | 0 | 0 | 179 | M | H | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,140 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.225365 | 0.075586 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180962,"numValue":-0.225364502302074,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180963,"numValue":0.0755864920562128,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,609 | train | mutant | 3,783,567 | 225 | 3,787,512 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179I | M179I | 1 | 1 | 0 | 0 | 179 | M | I | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,791 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.117878 | 0.124395 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666264,"numValue":-0.117877568058902,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666265,"numValue":0.124394529536453,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10610 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,610 | train | mutant | 3,783,567 | 225 | 3,787,512 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179I | M179I | 1 | 1 | 0 | 0 | 179 | M | I | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,187 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.236187 | 0.071348 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179056,"numValue":-0.236187344056285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179057,"numValue":0.0713480320486748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,611 | train | mutant | 3,783,567 | 225 | 3,787,512 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179I | M179I | 1 | 1 | 0 | 0 | 179 | M | I | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,141 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.170788 | 0.082876 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180964,"numValue":-0.170788089894134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180965,"numValue":0.0828761040065952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10612 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,612 | train | mutant | 3,783,568 | 225 | 3,787,513 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179K | M179K | 1 | 1 | 0 | 0 | 179 | M | K | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,792 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023478 | 0.082231 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666266,"numValue":-0.0234776108213665,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666267,"numValue":0.0822305457529797,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10613 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,613 | train | mutant | 3,783,568 | 225 | 3,787,513 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179K | M179K | 1 | 1 | 0 | 0 | 179 | M | K | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,188 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.223525 | 0.057575 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179058,"numValue":-0.223525398607978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179059,"numValue":0.0575753453560125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,614 | train | mutant | 3,783,568 | 225 | 3,787,513 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179K | M179K | 1 | 1 | 0 | 0 | 179 | M | K | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,142 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.216598 | 0.075515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180966,"numValue":-0.216597634075988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180967,"numValue":0.0755146987052587,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10615 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,615 | train | mutant | 3,783,569 | 225 | 3,787,514 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179L | M179L | 1 | 1 | 0 | 0 | 179 | M | L | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,793 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026647 | 0.107399 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666268,"numValue":-0.0266470165962486,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666269,"numValue":0.107398515998363,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,616 | train | mutant | 3,783,569 | 225 | 3,787,514 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179L | M179L | 1 | 1 | 0 | 0 | 179 | M | L | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,189 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074101 | 0.036898 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179060,"numValue":-0.0741013887659479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179061,"numValue":0.0368976124777801,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10617 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,617 | train | mutant | 3,783,569 | 225 | 3,787,514 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179L | M179L | 1 | 1 | 0 | 0 | 179 | M | L | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,143 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.06476 | 0.037071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180968,"numValue":-0.064760012209122,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180969,"numValue":0.0370710743720824,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,618 | train | mutant | 3,783,570 | 225 | 3,787,515 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179N | M179N | 1 | 1 | 0 | 0 | 179 | M | N | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,794 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.388218 | 0.183813 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666270,"numValue":0.38821815924448,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666271,"numValue":0.18381293630126,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,619 | train | mutant | 3,783,570 | 225 | 3,787,515 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179N | M179N | 1 | 1 | 0 | 0 | 179 | M | N | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,830 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.572677 | 0.087001 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180342,"numValue":-0.57267745654904,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180343,"numValue":0.0870011264200107,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10620 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,620 | train | mutant | 3,783,570 | 225 | 3,787,515 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179N | M179N | 1 | 1 | 0 | 0 | 179 | M | N | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,764 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.443673 | 0.074624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182210,"numValue":-0.443672986814421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182211,"numValue":0.0746244044558157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10621 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,621 | train | mutant | 3,783,571 | 225 | 3,787,516 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179P | M179P | 1 | 1 | 0 | 0 | 179 | M | P | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,795 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.257529 | 0.068987 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666272,"numValue":0.257529473794675,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666273,"numValue":0.0689874848921792,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,622 | train | mutant | 3,783,571 | 225 | 3,787,516 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179P | M179P | 1 | 1 | 0 | 0 | 179 | M | P | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,831 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.724903 | 0.13542 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180344,"numValue":-0.724903193770509,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180345,"numValue":0.13542030428671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10624 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,624 | train | mutant | 3,783,572 | 225 | 3,787,517 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Q | M179Q | 1 | 1 | 0 | 0 | 179 | M | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,796 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100773 | 0.095386 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666274,"numValue":-0.100772757888646,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666275,"numValue":0.0953864266224634,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10625 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,625 | train | mutant | 3,783,572 | 225 | 3,787,517 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Q | M179Q | 1 | 1 | 0 | 0 | 179 | M | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,832 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.139069 | 0.084975 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180346,"numValue":-0.13906891711257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180347,"numValue":0.084975287668015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10626 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,626 | train | mutant | 3,783,572 | 225 | 3,787,517 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Q | M179Q | 1 | 1 | 0 | 0 | 179 | M | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,766 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.202245 | 0.076491 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182214,"numValue":-0.202245342366491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182215,"numValue":0.0764911733246525,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,627 | train | mutant | 3,783,573 | 225 | 3,787,518 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179R | M179R | 1 | 1 | 0 | 0 | 179 | M | R | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,797 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027399 | 0.092287 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666276,"numValue":0.0273989786237348,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666277,"numValue":0.0922874150277811,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10628 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,628 | train | mutant | 3,783,573 | 225 | 3,787,518 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179R | M179R | 1 | 1 | 0 | 0 | 179 | M | R | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,833 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.293595 | 0.046492 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180348,"numValue":-0.293594690197947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180349,"numValue":0.0464924445823415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,629 | train | mutant | 3,783,573 | 225 | 3,787,518 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179R | M179R | 1 | 1 | 0 | 0 | 179 | M | R | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,767 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.481395 | 0.038014 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182216,"numValue":-0.48139461667161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182217,"numValue":0.0380139414820759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,630 | train | mutant | 3,783,574 | 225 | 3,787,519 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179S | M179S | 1 | 1 | 0 | 0 | 179 | M | S | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,798 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008731 | 0.067434 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666278,"numValue":-0.00873109177177319,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666279,"numValue":0.0674341700199148,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,631 | train | mutant | 3,783,574 | 225 | 3,787,519 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179S | M179S | 1 | 1 | 0 | 0 | 179 | M | S | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,834 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.149801 | 0.036755 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180350,"numValue":-0.149801112455611,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180351,"numValue":0.0367549008944598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,632 | train | mutant | 3,783,574 | 225 | 3,787,519 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179S | M179S | 1 | 1 | 0 | 0 | 179 | M | S | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,768 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067116 | 0.041903 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182218,"numValue":-0.0671157979798181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182219,"numValue":0.0419033267802116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10633 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,633 | train | mutant | 3,783,575 | 225 | 3,787,520 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179T | M179T | 1 | 1 | 0 | 0 | 179 | M | T | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,799 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.069094 | 0.086831 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666280,"numValue":0.069093940940641,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666281,"numValue":0.0868311475706135,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,635 | train | mutant | 3,783,575 | 225 | 3,787,520 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179T | M179T | 1 | 1 | 0 | 0 | 179 | M | T | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,769 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.431837 | 0.096921 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182220,"numValue":-0.431836651628984,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182221,"numValue":0.0969210946600825,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,636 | train | mutant | 3,783,576 | 225 | 3,787,521 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179V | M179V | 1 | 1 | 0 | 0 | 179 | M | V | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,800 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072117 | 0.101322 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666282,"numValue":-0.0721170748626268,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666283,"numValue":0.101322259425675,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,637 | train | mutant | 3,783,576 | 225 | 3,787,521 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179V | M179V | 1 | 1 | 0 | 0 | 179 | M | V | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,836 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.144316 | 0.035279 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180354,"numValue":-0.144316445020013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180355,"numValue":0.0352793636352785,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,638 | train | mutant | 3,783,576 | 225 | 3,787,521 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179V | M179V | 1 | 1 | 0 | 0 | 179 | M | V | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,770 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047825 | 0.034915 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182222,"numValue":-0.0478251442816907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182223,"numValue":0.0349154240838733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10639 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,639 | train | mutant | 3,783,577 | 225 | 3,787,522 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179W | M179W | 1 | 1 | 0 | 0 | 179 | M | W | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,801 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.301469 | 0.058802 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666284,"numValue":0.301468610273271,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666285,"numValue":0.0588022368517356,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10640 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,640 | train | mutant | 3,783,577 | 225 | 3,787,522 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179W | M179W | 1 | 1 | 0 | 0 | 179 | M | W | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,837 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.387337 | 0.039974 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180356,"numValue":-0.387337323552781,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180357,"numValue":0.0399735587250515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10641 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,641 | train | mutant | 3,783,577 | 225 | 3,787,522 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179W | M179W | 1 | 1 | 0 | 0 | 179 | M | W | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,771 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.375643 | 0.04455 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182224,"numValue":-0.375642939844171,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182225,"numValue":0.044549588590612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10642 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,642 | train | mutant | 3,783,578 | 225 | 3,787,523 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Y | M179Y | 1 | 1 | 0 | 0 | 179 | M | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 3,836,802 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.169177 | 0.09424 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9666286,"numValue":0.169176658744158,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9666287,"numValue":0.0942402720395624,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,643 | train | mutant | 3,783,578 | 225 | 3,787,523 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Y | M179Y | 1 | 1 | 0 | 0 | 179 | M | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,838 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.325606 | 0.065337 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180358,"numValue":-0.325605625709615,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180359,"numValue":0.0653374587585715,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10644 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,644 | train | mutant | 3,783,578 | 225 | 3,787,523 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | M179Y | M179Y | 1 | 1 | 0 | 0 | 179 | M | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,772 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.616165 | 0.131459 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182226,"numValue":-0.616164981687469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182227,"numValue":0.13145851576602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,645 | train | mutant | 4,905,667 | 225 | 4,912,255 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delM179 | delM179 | 1 | 0 | 1 | 0 | 179 | M | - | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,093,179 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.417477 | 0.188098 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179040,"numValue":-1.41747730795901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179041,"numValue":0.188097623338335,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10646 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,646 | train | mutant | 4,905,667 | 225 | 4,912,255 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delM179 | delM179 | 1 | 0 | 1 | 0 | 179 | M | - | 9 | CONSERVATION | 1K9Q | 347 | null | 179 | A | E | false | false | 83.222814 | null | 5,094,133 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.288625 | 0.153753 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180948,"numValue":-1.2886252347569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180949,"numValue":0.153752796321785,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16843,"numValue":9.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10647 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,647 | train | mutant | 199 | 225 | 228 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 374 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | null | NaCl | 100 mM | 1K9Q_A:A20R | 63 | 11.4 | null | null | null | null | 29.9 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl... | [{"datasets":[],"id":1539,"numValue":63.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":1540,"numValue":11.4,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":1541,"numValue":29.9,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":1542,"numValue":null,"references":[],"... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,648 | train | mutant | 199 | 225 | 228 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 377 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | null | NaCl | 2 M | 1K9Q_A:A20R | 59.3 | 6.4 | null | null | null | null | 20.9 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | HotMuSiC_S1626.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"... | [{"datasets":["HotMuSiC_S1626.csv"],"id":1551,"numValue":59.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":1552,"numValue":6.4,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":1553,"numValue":20.9,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":1554,"numValue":nul... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:10649 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,649 | train | mutant | 199 | 225 | 228 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,108 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084643 | 0.079824 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668898,"numValue":-0.0846428773504859,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668899,"numValue":0.0798235029744216,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10650 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,650 | train | mutant | 199 | 225 | 228 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,824 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.051234 | 0.034165 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180330,"numValue":-0.0512344664362793,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180331,"numValue":0.0341652067114809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10651 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,651 | train | mutant | 199 | 225 | 228 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,758 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.121037 | 0.035608 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182198,"numValue":-0.121036644251207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182199,"numValue":0.0356075956160485,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10652 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,652 | train | mutant | 7,302 | 225 | 7,972 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|D194T | A180R|D194T | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|194 | A | E|T | false | false | 60.468398 | null | 15,658 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | null | NaCl | 100 mM | 1K9Q_A:A20R 1K9Q_A:D34T | 68 | 16.4 | null | null | null | null | 34.7 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl... | [{"datasets":[],"id":57463,"numValue":68.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57464,"numValue":16.4,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57465,"numValue":34.7,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57466,"numValue":null,"references":... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10653 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,653 | train | mutant | 7,302 | 225 | 7,972 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|D194T | A180R|D194T | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|194 | A | E|T | false | false | 60.468398 | null | 15,661 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | null | NaCl | 2 M | 1K9Q_A:A20R 1K9Q_A:D34T | 68.4 | 15.5 | null | null | null | null | 29.6 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"... | [{"datasets":[],"id":57475,"numValue":68.4,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57476,"numValue":15.5,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57477,"numValue":29.6,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57478,"numValue":null,"references":... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,654 | train | mutant | 7,302 | 225 | 7,972 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|D194T | A180R|D194T | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|194 | A | E|T | false | false | 60.468398 | null | 16,740 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | 65 | NaCl | 100 mM | 1K9Q_A:A20R 1K9Q_A:D34T | null | null | 0.26 | -1.34 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":65.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 ... | [{"datasets":[],"id":61550,"numValue":0.26,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61551,"numValue":-1.34,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61552,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,655 | train | mutant | 7,302 | 225 | 7,972 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|D194T | A180R|D194T | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|194 | A | E|T | false | false | 60.468398 | null | 16,743 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | 65 | NaCl | 2 M | 1K9Q_A:A20R 1K9Q_A:D34T | null | null | 0.25 | -1.24 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":65.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type"... | [{"datasets":[],"id":61559,"numValue":0.25,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61560,"numValue":-1.24,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61561,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,656 | train | mutant | 7,303 | 225 | 7,973 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y | A180R|L190Y | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190 | A | E | false | false | 20.519214 | null | 15,659 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | null | NaCl | 100 mM | 1K9Q_A:A20R 1K9Q_A:L30Y | 73.7 | 22.1 | null | null | null | null | 34.5 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl... | [{"datasets":[],"id":57467,"numValue":73.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57468,"numValue":22.1,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57469,"numValue":34.5,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57470,"numValue":null,"references":... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,657 | train | mutant | 7,303 | 225 | 7,973 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y | A180R|L190Y | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190 | A | E | false | false | 20.519214 | null | 15,662 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | null | NaCl | 2 M | 1K9Q_A:A20R 1K9Q_A:L30Y | 73.9 | 21 | null | null | null | null | 32.6 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"... | [{"datasets":[],"id":57479,"numValue":73.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57480,"numValue":21.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57481,"numValue":32.6,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57482,"numValue":null,"references":... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10659 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,659 | train | mutant | 7,303 | 225 | 7,973 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y | A180R|L190Y | 2 | 2 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190 | A | E | false | false | 20.519214 | null | 16,744 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | 65 | NaCl | 2 M | 1K9Q_A:A20R 1K9Q_A:L30Y | null | null | 0.76 | -1.75 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":65.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type"... | [{"datasets":[],"id":61562,"numValue":0.76,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61563,"numValue":-1.75,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61564,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:10660 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,660 | train | mutant | 7,304 | 225 | 7,974 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y|D194T | A180R|L190Y|D194T | 3 | 3 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190|194 | A | E|T | false | false | 43.940281 | null | 15,660 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | null | NaCl | 100 mM | 1K9Q_A:A20R 1K9Q_A:L30Y 1K9Q_A:D34T | 79.6 | 28 | null | null | null | null | 40.7 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl... | [{"datasets":[],"id":57471,"numValue":79.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57472,"numValue":28.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57473,"numValue":40.7,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57474,"numValue":null,"references":... | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionR... | ||||||||||||
fireprotdb:10662 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,662 | train | mutant | 7,304 | 225 | 7,974 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y|D194T | A180R|L190Y|D194T | 3 | 3 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190|194 | A | E|T | false | false | 43.940281 | null | 16,742 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | 65 | NaCl | 100 mM | 1K9Q_A:A20R 1K9Q_A:L30Y 1K9Q_A:D34T | null | null | 1.46 | -2.54 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":65.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 ... | [{"datasets":[],"id":61556,"numValue":1.46,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61557,"numValue":-2.54,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61558,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionR... | ||||||||||||
fireprotdb:10663 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,663 | train | mutant | 7,304 | 225 | 7,974 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180R|L190Y|D194T | A180R|L190Y|D194T | 3 | 3 | 0 | 0 | 180 | A | R | 9 | CONSERVATION | 1K9Q | 347 | null | 180|190|194 | A | E|T | false | false | 43.940281 | null | 16,745 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | 65 | NaCl | 2 M | 1K9Q_A:A20R 1K9Q_A:L30Y 1K9Q_A:D34T | null | null | 0.99 | -1.98 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":65.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type"... | [{"datasets":[],"id":61565,"numValue":0.99,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61566,"numValue":-1.98,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61567,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionR... | ||||||||||||
fireprotdb:10664 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,664 | train | mutant | 3,784,870 | 225 | 3,788,815 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180C | A180C | 1 | 1 | 0 | 0 | 180 | A | C | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,095 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.019351 | 0.073171 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668872,"numValue":0.019350608111891,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668873,"numValue":0.0731706075970976,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10665 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,665 | train | mutant | 3,784,870 | 225 | 3,788,815 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180C | A180C | 1 | 1 | 0 | 0 | 180 | A | C | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,811 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.256135 | 0.061458 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180304,"numValue":-0.256134621920038,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180305,"numValue":0.0614580083693864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10666 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,666 | train | mutant | 3,784,870 | 225 | 3,788,815 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180C | A180C | 1 | 1 | 0 | 0 | 180 | A | C | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,745 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238015 | 0.068439 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182172,"numValue":-0.238015156937129,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182173,"numValue":0.0684388580130035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10667 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,667 | train | mutant | 3,784,871 | 225 | 3,788,816 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180D | A180D | 1 | 1 | 0 | 0 | 180 | A | D | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,096 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.136403 | 0.0798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668874,"numValue":0.136402945996385,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668875,"numValue":0.0798002051643147,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10668 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,668 | train | mutant | 3,784,871 | 225 | 3,788,816 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180D | A180D | 1 | 1 | 0 | 0 | 180 | A | D | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,812 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.202118 | 0.050384 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180306,"numValue":-0.202117573313933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180307,"numValue":0.0503840927906813,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10669 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,669 | train | mutant | 3,784,871 | 225 | 3,788,816 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180D | A180D | 1 | 1 | 0 | 0 | 180 | A | D | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,746 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.306276 | 0.043627 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182174,"numValue":-0.306275537955357,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182175,"numValue":0.0436269908768404,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10671 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,671 | train | mutant | 3,784,872 | 225 | 3,788,817 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180E | A180E | 1 | 1 | 0 | 0 | 180 | A | E | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,813 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.378066 | 0.060433 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180308,"numValue":-0.378065675640031,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180309,"numValue":0.0604328114025272,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10672 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,672 | train | mutant | 3,784,872 | 225 | 3,788,817 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180E | A180E | 1 | 1 | 0 | 0 | 180 | A | E | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,747 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.36414 | 0.053052 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182176,"numValue":-0.364139703128115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182177,"numValue":0.0530523735152911,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10673 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,673 | train | mutant | 3,784,873 | 225 | 3,788,818 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180F | A180F | 1 | 1 | 0 | 0 | 180 | A | F | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,098 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.169317 | 0.054354 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668878,"numValue":0.169317003743991,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668879,"numValue":0.0543544098837431,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10674 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,674 | train | mutant | 3,784,873 | 225 | 3,788,818 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180F | A180F | 1 | 1 | 0 | 0 | 180 | A | F | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,814 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.338171 | 0.056522 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180310,"numValue":-0.338171119912525,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180311,"numValue":0.0565216263780145,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10675 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,675 | train | mutant | 3,784,873 | 225 | 3,788,818 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180F | A180F | 1 | 1 | 0 | 0 | 180 | A | F | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,748 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.54622 | 0.107583 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182178,"numValue":-0.546220043750358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182179,"numValue":0.107583364048969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10676 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,676 | train | mutant | 3,784,874 | 225 | 3,788,819 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180G | A180G | 1 | 1 | 0 | 0 | 180 | A | G | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,099 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.105001 | 0.084163 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668880,"numValue":0.105001263161263,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668881,"numValue":0.0841626525899942,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10677 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,677 | train | mutant | 3,784,874 | 225 | 3,788,819 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180G | A180G | 1 | 1 | 0 | 0 | 180 | A | G | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,815 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.229062 | 0.041106 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180312,"numValue":-0.22906228025161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180313,"numValue":0.0411064474959814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10678 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,678 | train | mutant | 3,784,874 | 225 | 3,788,819 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180G | A180G | 1 | 1 | 0 | 0 | 180 | A | G | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,749 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.340548 | 0.041217 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182180,"numValue":-0.340547826854069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182181,"numValue":0.0412166549163819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10679 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,679 | train | mutant | 3,784,875 | 225 | 3,788,820 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180H | A180H | 1 | 1 | 0 | 0 | 180 | A | H | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,100 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.128322 | 0.049785 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668882,"numValue":0.128321533869483,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668883,"numValue":0.0497845867418262,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10680 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,680 | train | mutant | 3,784,875 | 225 | 3,788,820 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180H | A180H | 1 | 1 | 0 | 0 | 180 | A | H | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,816 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.247102 | 0.051646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180314,"numValue":-0.247101563930112,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180315,"numValue":0.0516461029468959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10681 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,681 | train | mutant | 3,784,875 | 225 | 3,788,820 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180H | A180H | 1 | 1 | 0 | 0 | 180 | A | H | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,750 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.313935 | 0.057196 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182182,"numValue":-0.313935385310857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182183,"numValue":0.0571962602184378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10682 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,682 | train | mutant | 3,784,876 | 225 | 3,788,821 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180I | A180I | 1 | 1 | 0 | 0 | 180 | A | I | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,101 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.174389 | 0.145086 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668884,"numValue":0.174389239929808,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668885,"numValue":0.145086212216219,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10683 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,683 | train | mutant | 3,784,876 | 225 | 3,788,821 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180I | A180I | 1 | 1 | 0 | 0 | 180 | A | I | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,817 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.468544 | 0.096148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180316,"numValue":-0.46854419579539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180317,"numValue":0.0961484755097452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10684 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,684 | train | mutant | 3,784,876 | 225 | 3,788,821 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180I | A180I | 1 | 1 | 0 | 0 | 180 | A | I | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,751 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.418098 | 0.085379 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182184,"numValue":-0.418098111567328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182185,"numValue":0.0853793035679967,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10685 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,685 | train | mutant | 3,784,877 | 225 | 3,788,822 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180K | A180K | 1 | 1 | 0 | 0 | 180 | A | K | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,102 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079315 | 0.058773 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668886,"numValue":-0.0793149053881941,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668887,"numValue":0.0587729638014979,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10686 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,686 | train | mutant | 3,784,877 | 225 | 3,788,822 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180K | A180K | 1 | 1 | 0 | 0 | 180 | A | K | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,818 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.14595 | 0.069185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180318,"numValue":-0.145949589415751,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180319,"numValue":0.069184869929549,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10687 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,687 | train | mutant | 3,784,877 | 225 | 3,788,822 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180K | A180K | 1 | 1 | 0 | 0 | 180 | A | K | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,752 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.139488 | 0.070773 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182186,"numValue":-0.13948817329455,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182187,"numValue":0.0707725104534893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10688 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,688 | train | mutant | 3,784,878 | 225 | 3,788,823 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180L | A180L | 1 | 1 | 0 | 0 | 180 | A | L | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,103 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.113004 | 0.063173 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668888,"numValue":0.113003613071293,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668889,"numValue":0.0631726951502005,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10689 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,689 | train | mutant | 3,784,878 | 225 | 3,788,823 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180L | A180L | 1 | 1 | 0 | 0 | 180 | A | L | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,819 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.332687 | 0.057393 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180320,"numValue":-0.332687177674261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180321,"numValue":0.0573927986831461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10690 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,690 | train | mutant | 3,784,878 | 225 | 3,788,823 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180L | A180L | 1 | 1 | 0 | 0 | 180 | A | L | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,753 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.237386 | 0.048061 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182188,"numValue":-0.237385813446041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182189,"numValue":0.0480606094635366,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10691 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,691 | train | mutant | 3,784,879 | 225 | 3,788,824 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180M | A180M | 1 | 1 | 0 | 0 | 180 | A | M | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,104 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.000624 | 0.074866 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668890,"numValue":0.000623834649536199,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668891,"numValue":0.0748660341597794,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10692 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,692 | train | mutant | 3,784,879 | 225 | 3,788,824 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180M | A180M | 1 | 1 | 0 | 0 | 180 | A | M | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,820 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.329216 | 0.074542 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180322,"numValue":-0.32921638323465,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180323,"numValue":0.0745422362251704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10693 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,693 | train | mutant | 3,784,879 | 225 | 3,788,824 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180M | A180M | 1 | 1 | 0 | 0 | 180 | A | M | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,754 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.232598 | 0.04872 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182190,"numValue":-0.232598408848853,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182191,"numValue":0.0487199672528769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10695 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,695 | train | mutant | 3,784,880 | 225 | 3,788,825 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180N | A180N | 1 | 1 | 0 | 0 | 180 | A | N | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,821 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.15979 | 0.087978 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180324,"numValue":-0.159789980531497,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180325,"numValue":0.0879777496694514,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10696 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,696 | train | mutant | 3,784,880 | 225 | 3,788,825 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180N | A180N | 1 | 1 | 0 | 0 | 180 | A | N | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,755 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.192877 | 0.045288 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182192,"numValue":-0.192877479455222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182193,"numValue":0.0452877985835767,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10697 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,697 | train | mutant | 3,784,881 | 225 | 3,788,826 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180P | A180P | 1 | 1 | 0 | 0 | 180 | A | P | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,106 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.105317 | 0.092129 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668894,"numValue":1.10531657354471,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668895,"numValue":0.0921287392065305,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10698 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,698 | train | mutant | 3,784,881 | 225 | 3,788,826 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180P | A180P | 1 | 1 | 0 | 0 | 180 | A | P | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,822 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.088688 | 0.144027 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180326,"numValue":-1.08868755831584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180327,"numValue":0.144026801204889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10699 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,699 | train | mutant | 3,784,881 | 225 | 3,788,826 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180P | A180P | 1 | 1 | 0 | 0 | 180 | A | P | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,756 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.002837 | 0.158734 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182194,"numValue":-1.00283688272491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182195,"numValue":0.158734035879347,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10700 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,700 | train | mutant | 3,784,882 | 225 | 3,788,827 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180Q | A180Q | 1 | 1 | 0 | 0 | 180 | A | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,107 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003637 | 0.120324 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668896,"numValue":0.0036374883072934,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668897,"numValue":0.120324085681865,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10701 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,701 | train | mutant | 3,784,882 | 225 | 3,788,827 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180Q | A180Q | 1 | 1 | 0 | 0 | 180 | A | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,823 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.177478 | 0.049354 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180328,"numValue":-0.177478268700435,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180329,"numValue":0.0493540152457655,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10702 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,702 | train | mutant | 3,784,882 | 225 | 3,788,827 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180Q | A180Q | 1 | 1 | 0 | 0 | 180 | A | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,094,757 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.178189 | 0.079677 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182196,"numValue":-0.178188545675605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182197,"numValue":0.079676586900155,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10703 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,703 | train | mutant | 3,784,883 | 225 | 3,788,828 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180S | A180S | 1 | 1 | 0 | 0 | 180 | A | S | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,109 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.031778 | 0.088828 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668900,"numValue":0.031778179227393,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668901,"numValue":0.0888282067307144,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10704 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,704 | train | mutant | 3,784,883 | 225 | 3,788,828 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180S | A180S | 1 | 1 | 0 | 0 | 180 | A | S | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,825 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.110106 | 0.04852 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180332,"numValue":-0.110105985994902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180333,"numValue":0.0485204371704187,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10706 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,706 | train | mutant | 3,784,884 | 225 | 3,788,829 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180T | A180T | 1 | 1 | 0 | 0 | 180 | A | T | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 3,838,110 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.119933 | 0.068343 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9668902,"numValue":0.119933185697565,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9668903,"numValue":0.0683429320258461,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:10707 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 10,707 | train | mutant | 3,784,884 | 225 | 3,788,829 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | A180T | A180T | 1 | 1 | 0 | 0 | 180 | A | T | 9 | CONSERVATION | 1K9Q | 347 | null | 180 | A | E | false | false | 30.154381 | null | 5,093,826 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.202161 | 0.059733 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180334,"numValue":-0.202161085153962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180335,"numValue":0.0597333585740683,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16844,"numValue":9.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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