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GO

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go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:7770033
7,770,033
octopamine transport
biological_process
The directed movement of octopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Octopamine is a monoamine neurotransmitter occurring predominantly in invertebrates.
[ "PMID:15849736", "PMID:32305263", "PMID:9870940" ]
null
[]
[]
[]
[]
[]
[ "GO:0015695", "GO:0015850", "GO:0071705" ]
[]
[]
[]
[ "GO:0015695", "GO:0015850", "GO:0071705" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31143\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
3
GO:7770034
7,770,034
nickel-pincer nucleotide cofactor biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of nickel-pincer nucleotide (NPN) cofactor, also known as nickel pyridinium-3,5-bisthiocarboxylic acid mononucleotide.
[ "PMID:24710389", "PMID:27114550", "PMID:33093595", "PMID:39667499", "PMID:39827451" ]
null
[ "NPN cofactor biosynthetic process" ]
[ "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7928", "MetaCyc:PWY-8561" ]
[ "GO:0051191" ]
[]
[]
[]
[ "GO:0051191" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch MetaCyc:PWY-7928", "skos:narrowMatch MetaCyc:PWY-8561", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31252\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31634\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
9
GO:7770035
7,770,035
negative regulation of ER to Golgi vesicle-mediated transport
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
[ "PMID:21693198" ]
null
[]
[]
[]
[]
[]
[ "GO:0032387", "GO:0060628" ]
[ "negatively_regulates GO:0006888" ]
[ "negatively_regulates" ]
[ "GO:0006888" ]
[ "GO:0006888", "GO:0032387", "GO:0060628" ]
[ "GO:0065007", "negatively_regulates GO:0006888" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31273\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
2
GO:7770036
7,770,036
flavin transferase activity
molecular_function
Catalysis of the reaction: L-threonyl-[protein] + FAD = FMN-L-threonyl-[protein] + AMP + H+.
[ "RHEA:36847" ]
null
[ "FAD:protein FMN transferase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:2.7.1.180", "RHEA:36847" ]
[ "GO:0016773" ]
[]
[]
[]
[ "GO:0016773" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.7.1.180", "skos:exactMatch RHEA:36847", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31349\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
5
GO:7770037
7,770,037
glial scar formation
biological_process
The process by which central nervous system glial and associated cells assemble and stabilize a dense, organized glial border at the site of injury. This involves proliferation and reorganization of reactive astrocytes and NG2 glia (oligodendrocyte precursor cells), deposition of extracellular matrix components, and fo...
[ "PMID:20012068", "PMID:23904622", "PMID:27027288" ]
Distinct from connective tissue replacement involved in inflammatory response wound healing (GO:0002248) as CNS glial scars differ in cellular origin and molecular composition.
[]
[]
[]
[]
[]
[ "GO:0002246" ]
[ "part_of GO:0150103" ]
[ "part_of" ]
[ "GO:0150103" ]
[ "GO:0002246", "GO:0150103" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30887\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
2
GO:7770039
7,770,039
melanosomal lumen pH elevation
biological_process
Any process that increases the pH of the melanosomal lumen, corresponding to a decrease in hydrogen ion concentration.
[ "PMID:11310796", "PMID:27140606", "PMID:32966160", "PMID:35469906" ]
null
[ "melanosome pH elevation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0051454" ]
[]
[]
[]
[ "GO:0051454" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28838\" xsd:anyURI" ]
dragon-ai-agent
null
false
true
6
GO:7770040
7,770,040
epiplastidial membrane
cellular_component
The outermost lipid bilayer surrounding complex plastids in organisms that acquired their plastids through secondary endosymbiosis. This membrane is derived from the host cell's endomembrane system and is continuous with the rough endoplasmic reticulum and the outer nuclear envelope. In some species, the cytoplasmic fa...
[ "PMID:15937721", "PMID:27179349", "PMID:39383259" ]
null
[ "cERM", "chloroplast ER membrane", "epiplastid rough ER", "EpM", "EPrER" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0042170" ]
[]
[]
[]
[ "GO:0042170" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31421\" xsd:anyURI" ]
dragon-ai-agent
2026-01-29T01:11:34Z
false
true
5
GO:7770041
7,770,041
periplastidial membrane
cellular_component
The lipid bilayer that forms the second outermost membrane of complex plastids in organisms that acquired their plastids through secondary endosymbiosis. The periplastidial membrane is evolutionarily derived from the plasma membrane of the engulfed algal endosymbiont and together with the outer envelope membrane of the...
[ "PMID:15937721", "PMID:27179349", "PMID:39383259" ]
null
[ "PPM" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0042170" ]
[]
[]
[]
[ "GO:0042170" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31421\" xsd:anyURI" ]
dragon-ai-agent
2026-01-29T01:11:34Z
false
true
6
GO:7770042
7,770,042
bindosome complex
cellular_component
A membrane-associated protein complex found in archaea that consists of sugar binding proteins assembled via a type IV pilin-like assembly system. The complex is located at the cell surface and functions in sugar uptake by facilitating the interaction between solute binding proteins and ABC transporters. The complex fo...
[ "PMID:21234771", "PMID:38877064" ]
null
[]
[]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31422\" xsd:anyURI" ]
dragon-ai-agent
2026-01-29T01:57:42Z
false
true
1
GO:7770043
7,770,043
lipid chaperone activity
molecular_function
Binding to a lipid and delivering it to an acceptor protein, including enzymes, nuclear receptors, and other lipid-binding proteins. The lipid may be presented while bound to the chaperone for enzymatic modification or signaling, or fully transferred to the acceptor protein.
[ "PMID:16216074", "PMID:18511927", "PMID:25847235", "PMID:26658141" ]
null
[]
[]
[]
[]
[]
[ "GO:0005319" ]
[ "has_part GO:0008289" ]
[ "has_part" ]
[ "GO:0008289" ]
[ "GO:0005319", "GO:0008289" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31403\" xsd:anyURI" ]
dragon-ai-agent
2026-01-30T01:54:24Z
false
true
9
GO:7770044
7,770,044
phycoerythrobilin synthase activity
molecular_function
Catalysis of the reaction: biliverdin IXalpha + 2 reduced ferredoxin + 4 H+ = (3Z)-phycoerythrobilin + 2 oxidized ferredoxin.
[ "PMID:18662988", "RHEA:25359" ]
null
[]
[]
[]
[]
[ "EC:1.3.7.6", "RHEA:25359" ]
[ "GO:0016636" ]
[]
[]
[]
[ "GO:0016636" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.3.7.6", "skos:exactMatch RHEA:25359", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31443\" xsd:anyURI" ]
dragon-ai-agent
2026-01-30T04:39:58Z
false
true
6
GO:7770046
7,770,046
obsolete N6-methyladenosine kinase activity
molecular_function
OBSOLETE. Catalysis of the reaction: ATP + N6-methyladenosine = ADP + H+ + N6-methyl-AMP.
[ "PMID:40840445" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30800\" xsd:anyURI" ]
dragon-ai-agent
2026-02-09T05:59:37Z
true
true
8
GO:7770047
7,770,047
obsolete N6,N6-dimethyladenosine kinase activity
molecular_function
OBSOLETE. Catalysis of the reaction: ATP + N6,N6-dimethyladenosine = ADP + H+ + N6,N6-dimethyl-AMP.
[ "PMID:40840445" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30800\" xsd:anyURI" ]
dragon-ai-agent
2026-02-09T05:59:37Z
true
true
8
GO:7770048
7,770,048
obsolete N6-isopentenyladenosine kinase activity
molecular_function
OBSOLETE. Catalysis of the reaction: ATP + N6-isopentenyladenosine = ADP + H+ + N6-isopentenyl-AMP.
[ "PMID:40840445" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30800\" xsd:anyURI" ]
dragon-ai-agent
2026-02-09T05:59:37Z
true
true
4
GO:7770049
7,770,049
obsolete N6,N6-dimethyl-AMP deaminase activity
molecular_function
OBSOLETE. Catalysis of the reaction: H2O + H+ + N6,N6-dimethyl-AMP = IMP + dimethylamine.
[ "PMID:40840445" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30800\" xsd:anyURI" ]
dragon-ai-agent
2026-02-09T05:59:37Z
true
true
6
GO:7770050
7,770,050
obsolete N6-isopentenyl-AMP deaminase activity
molecular_function
OBSOLETE. Catalysis of the reaction: H2O + H+ + N6-isopentenyl-AMP = IMP + dimethylallylamine.
[ "PMID:40840445" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30800\" xsd:anyURI" ]
dragon-ai-agent
2026-02-09T05:59:37Z
true
true
5
GO:7770051
7,770,051
mitochondrial-lysosomal membrane contact site
cellular_component
An organelle membrane contact site between the mitochondrial outer membrane and the lysosomal membrane.
[ "PMID:29364868", "PMID:30898429", "PMID:32703809", "PMID:33372681", "PMID:33753743", "PMID:35249745" ]
null
[ "lysosome-mitochondrion membrane contact site", "mitochondria-lysosome contact site", "mitochondria-lysosome MCS", "mitochondria-lysosome membrane contact site" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990816" ]
[]
[]
[]
[ "GO:1990816" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31553\" xsd:anyURI" ]
dragon-ai-agent
2026-02-11T18:32:29Z
false
true
5
GO:7770052
7,770,052
endoplasmic reticulum-lysosome membrane contact site
cellular_component
An organelle membrane contact site between the endoplasmic reticulum membrane and the lysosomal membrane.
[ "PMID:31537798", "PMID:39370902" ]
null
[ "ER-lysosome contact site", "ER-lysosome MCS", "lysosome-ER membrane contact site" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098853" ]
[]
[]
[]
[ "GO:0098853" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31541\" xsd:anyURI" ]
dragon-ai-agent
2026-02-12T00:09:12Z
false
true
4
GO:7770053
7,770,053
nucleotide-binding leucine-rich repeat receptor complex
cellular_component
A protein complex that contains one or more nucleotide-binding leucine-rich repeat (NLR) proteins and functions as an intracellular innate immune receptor. Upon activation by pathogen effectors or danger signals, the complex oligomerizes with adaptor and effector proteins to trigger downstream immune responses includin...
[ "PMID:26355215", "PMID:30948526", "PMID:30948527" ]
null
[ "NLR complex", "NLR receptor complex", "NOD-like receptor complex" ]
[ "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0043235" ]
[]
[]
[]
[ "GO:0043235" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31604\" xsd:anyURI" ]
dragon-ai-agent
2026-02-19T17:46:49Z
false
true
5
GO:7770054
7,770,054
tRNA(Val) (adenine(37)-N6)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + adenosine(37) in tRNA(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenosine(37) in tRNA(Val) + H+.
[ "PMID:19383770", "RHEA:43160" ]
null
[]
[]
[]
[]
[ "EC:2.1.1.223", "RHEA:43160" ]
[ "GO:0008170", "GO:0016426" ]
[]
[]
[]
[ "GO:0008170", "GO:0016426" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.1.223", "skos:exactMatch RHEA:43160", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31644\" xsd:anyURI" ]
dragon-ai-agent
2026-02-28T05:25:40Z
false
true
3
GO:7770055
7,770,055
intestinal lumen acidification
biological_process
Any process that reduces the pH of the intestinal lumen, corresponding to an increase in hydrogen ion concentration.
[ "PMID:19741196" ]
null
[ "intestinal lumen pH reduction" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:7770056" ]
[]
[]
[]
[ "GO:7770056" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31657\" xsd:anyURI" ]
dragon-ai-agent
2026-03-03T02:00:57Z
false
true
8
GO:7770056
7,770,056
multicellular organismal-level extracellular fluid acidification
biological_process
Any process that reduces the pH of an extracellular fluid of a multicellular organism, corresponding to an increase in hydrogen ion concentration.
[ "PMID:33326313", "PMID:35666106" ]
null
[ "extracellular fluid pH reduction", "multicellular organismal-level extracellular fluid pH reduction" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032501", "GO:0045851" ]
[]
[]
[]
[ "GO:0032501", "GO:0045851" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29164\" xsd:anyURI" ]
dragon-ai-agent
2026-03-24T17:37:00Z
false
true
5