ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000168491
CCDC110
Coiled-coil domain containing 110
[ "Q8TBZ0" ]
4
185445182-185471752
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071931" ]
[ "CT52", "KM-HN-1", "MGC33607" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
1
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 51: Myeloma - Immunoglobulins
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 21: Testis - Mixed function
Group enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
6
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,141
7
ENSG00000168495
POLR3D
RNA polymerase III subunit D
[ "P05423" ]
8
22245133-22254601
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061331", "HPA067875", "HPA068461", "HPA069089" ]
[ "BN51T", "C53", "RPC4", "TSBN51" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins", "RNA polymerase related proteins" ]
[ "Antiviral defense", "Immunity", "Innate immunity", "Transcription" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
83
null
null
Cluster 14: Non-specific - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 40: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,142
6
ENSG00000168496
FEN1
Flap structure-specific endonuclease 1
[ "P39748" ]
11
61792911-61797238
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002262", "HPA006748", "HPA073857" ]
[ "FEN-1", "MF1", "RAD2" ]
[ "Cancer-related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "DNA replication" ]
[ "Endonuclease", "Exonuclease", "Hydrolase", "Nuclease" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Enhanced
null
35
null
Yes
Cluster 5: Non-specific - Cell proliferation
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
4
4
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,143
8
ENSG00000168497
CAVIN2
Caveolae associated protein 2
[ "O95810" ]
2
191834310-191847088
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039325", "HPA062122" ]
[ "cavin-2", "PS-p68", "SDPR", "SDR" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Enhanced
Enhanced
null
9
Yes
No
Cluster 21: Neutrophils - Unknown function
Cluster 47: Endothelial cells - Vasculature
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 47: Platelets - Hemostasis
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
4
Group enriched
Detected in many
12
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,144
8
ENSG00000168502
MTCL1
Microtubule crosslinking factor 1
[ "Q9Y4B5" ]
18
8705556-8832778
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046245" ]
[ "CCDC165", "KIAA0802", "SOGA2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
19
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 6: Leukemia - Signal transduction
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in many
5
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,145
6
ENSG00000168505
GBX2
Gastrulation brain homeobox 2
[ "P52951" ]
2
236165236-236168386
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA067809" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
null
Yes
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in single
12
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
8
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,146
5
ENSG00000168509
HJV
Hemojuvelin BMP co-receptor
[ "Q6ZVN8" ]
1
146017468-146036746
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "haemojuvelin", "hemojuvelin", "HFE2", "HFE2A", "JH", "RGMC" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
null
2
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in some
6
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in some
81
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,147
6
ENSG00000168522
FNTA
Farnesyltransferase, CAAX box, alpha
[ "P49354" ]
8
43034194-43085788
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010149", "HPA018830" ]
[ "FPTA", "PGGT1A", "PTAR2" ]
[ "Enzymes", "Essential proteins", "FDA approved drug targets", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Prenyltransferase", "Transferase" ]
[ "FDA approved drug targets" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
13
null
null
Cluster 25: Non-specific - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 40: Non-specific - Unknown function
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma" ]
12,150
2
ENSG00000168528
SERINC2
Serine incorporator 2
[ "Q96SA4" ]
1
31409565-31434680
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA005974" ]
[ "FKSG84", "PRO0899", "TDE2", "TDE2L" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
24
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
4
4
0
4
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,151
1
ENSG00000168530
MYL1
Myosin light chain 1
[ "P05976" ]
2
210290150-210315174
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046859", "HPA063034", "HPA073827" ]
[ "MLC-1", "MLC1", "MLC1/3", "MLC1F", "MLC3F" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Motor protein", "Muscle protein", "Myosin" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
5
null
null
null
null
Cluster 33: Sarcoma - Muscle contraction
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
87
Cancer enriched
Detected in some
17
Group enriched
Detected in some
18
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,152
3
ENSG00000168538
TRAPPC11
Trafficking protein particle complex subunit 11
[ "Q7Z392" ]
4
183659267-183713594
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038173" ]
[ "C4orf41", "FLJ12716", "foigr", "gry" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "ER-Golgi transport", "Transport" ]
[]
[ "Disease variant", "Limb-girdle muscular dystrophy" ]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Uncertain
null
null
42
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,153
9
ENSG00000168539
CHRM1
Cholinergic receptor muscarinic 1
[ "P11229" ]
11
62908679-62921807
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014101" ]
[]
[ "FDA approved drug targets", "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
Supported
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 78: Brain - Neuronal signaling
Group enriched
Detected in some
11
Group enriched
Detected in some
6
Group enriched
Detected in some
11
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Rectum Adenocarcinoma" ]
[ "Rectum Adenocarcinoma" ]
12,154
5
ENSG00000168542
COL3A1
Collagen type III alpha 1 chain
[ "P02461" ]
2
188974373-189012746
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007583", "CAB016766", "CAB059993" ]
[ "EDS4A" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Aortic aneurysm", "Disease variant", "Ehlers-Danlos syndrome", "FDA approved drug targets" ]
[ "Endoplasmic reticulum" ]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
Approved
Approved
null
1
null
null
null
Cluster 12: Non-specific - Vasculature
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,155
8
ENSG00000168546
GFRA2
GDNF family receptor alpha 2
[ "O00451" ]
8
21690398-21812357
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024704", "CAB032791" ]
[ "GDNFRB", "NTNRA", "RETL2", "TRNR2" ]
[ "Predicted intracellular proteins" ]
[]
[ "Receptor" ]
[]
[ "Plasma membrane" ]
[ "Vesicles" ]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Approved
Uncertain
null
2
null
null
Cluster 25: Non-specific - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
6
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,156
9
ENSG00000168556
ING2
Inhibitor of growth family member 2
[ "Q9H160" ]
4
183505058-183512429
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019486", "HPA021517" ]
[ "ING1L", "p33ING2" ]
[ "Predicted intracellular proteins" ]
[ "Growth regulation", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
51
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,157
8
ENSG00000168564
CDKN2AIP
CDKN2A interacting protein
[ "Q9NXV6" ]
4
183444635-183449064
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041397", "HPA062142" ]
[ "CARF", "FLJ20036" ]
[ "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
23
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,158
4
ENSG00000168566
SNRNP48
Small nuclear ribonucleoprotein U11/U12 subunit 48
[ "Q6IEG0" ]
6
7590198-7611967
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029234" ]
[ "C6orf151", "dJ336K20B.1", "dJ512B11.2", "FLJ32234" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
15
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 25: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 7: Non-specific - Transcription
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
12,159
5
ENSG00000168569
TMEM223
Transmembrane protein 223
[ "A0PJW6" ]
11
62771629-62792006
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014504" ]
[ "MGC3196", "Mrx15" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear membrane", "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
4
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 37: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
12,160
5
ENSG00000168575
SLC20A2
Solute carrier family 20 member 2
[ "Q08357" ]
8
42416475-42541926
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA026540" ]
[ "Glvr-2", "GLVR2", "MLVAR", "PiT-2", "Ram-1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Host-virus interaction", "Ion transport", "Phosphate transport", "Sodium transport", "Symport", "Transport" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
5
null
null
Cluster 33: Non-specific - ATP binding
Cluster 42: Choroid plexus - Mitochondria
Cluster 64: Connective tissue cells - ECM organization
Cluster 55: Myocytes - Oxidative muscle function
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
12,161
3
ENSG00000168582
CRYGA
Crystallin gamma A
[ "P11844" ]
2
208160740-208163589
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA043386" ]
[ "CRY-g-A", "CRYG1", "CRYG5" ]
[ "Predicted intracellular proteins" ]
[]
[ "Eye lens protein" ]
[]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Uncertain
Supported
null
null
null
null
null
null
null
Cluster 35: Neurons - Synaptic function & neurogenesis
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,162
7
ENSG00000168589
DYNLRB2
Dynein light chain roadblock-type 2
[ "Q8TF09" ]
16
80540734-80550811
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "DNCL2B", "DNLC2B", "ROBLD2" ]
[ "Predicted intracellular proteins" ]
[ "Transport" ]
[ "Motor protein" ]
[]
[]
[]
[]
[]
null
null
null
7
null
null
Cluster 30: Non-specific - DNA binding
Cluster 3: Choroid plexus - Cilium
Cluster 27: Breast cancer - Unknown function
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in many
5
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
12,163
8
ENSG00000168591
TMUB2
Transmembrane and ubiquitin like domain containing 2
[ "Q71RG4" ]
17
44186970-44191929
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043137" ]
[ "MGC3123" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
18
null
null
Cluster 41: Basophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,164
3
ENSG00000168594
ADAM29
ADAM metallopeptidase domain 29
[ "Q9UKF5" ]
4
174829668-174978180
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CT73", "svph1" ]
[ "Disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
null
null
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 51: Myeloma - Immunoglobulins
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
78
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
37
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,165
9
ENSG00000168610
STAT3
Signal transducer and activator of transcription 3
[ "P40763" ]
17
42313324-42388540
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001671", "CAB003859", "HPA058603", "CAB068241", "CAB068242", "CAB080518" ]
[ "APRF" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes", "Diabetes mellitus", "Disease variant", "Dwarfism" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Enhanced
Supported
null
191
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 44: Non-specific - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,166
5
ENSG00000168612
ZSWIM1
Zinc finger SWIM-type containing 1
[ "Q9BR11" ]
20
45881227-45885266
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA041147", "HPA046751" ]
[ "C20orf162", "dJ337O18.5" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 22: Eosinophils - Transcription
Cluster 48: Non-specific - Mixed function
Cluster 62: Non-specific - Plasma proteins
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,167
6
ENSG00000168615
ADAM9
ADAM metallopeptidase domain 9
[ "Q13443" ]
8
38996754-39105445
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004000" ]
[ "CORD9", "KIAA0021", "MCMP", "MDC9", "Mltng" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Cancer-related genes", "Cone-rod dystrophy" ]
[ "Vesicles" ]
[ "Endoplasmic reticulum" ]
[ "Secreted - unknown location" ]
[ "Enzyme" ]
Approved
null
null
38
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 15: Kidney cancer - Membrane components
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
4
0
4
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,168
4
ENSG00000168619
ADAM18
ADAM metallopeptidase domain 18
[ "Q9Y3Q7" ]
8
39584489-39730065
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "ADAM27", "tMDCIII" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Developmental protein" ]
null
null
null
null
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
74
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,169
8
ENSG00000168621
GDNF
Glial cell derived neurotrophic factor
[ "P39905" ]
5
37812677-37840041
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005210", "HPA070283" ]
[ "ATF1", "ATF2", "HFB1-GDNF" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor" ]
[ "Cancer-related genes", "Disease variant", "Hirschsprung disease" ]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[ "Secreted in other tissues" ]
[ "Growth factor" ]
Approved
Supported
null
3
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,170
5
ENSG00000168631
MUCL3
Mucin like 3
[ "Q3MIW9" ]
6
30934523-30954221
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014036" ]
[ "bCX105N19.6", "C6orf37", "DPCR1", "PBLT" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
null
Cluster 66: Non-specific - Mitochondria
Cluster 68: Foveolar cells - Mucosal defense
Cluster 60: Stomach - Digestion
Tissue enriched
Detected in some
19
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
12
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,171
1
ENSG00000168634
WFDC13
WAP four-disulfide core domain 13
[ "Q8IUB5" ]
20
45702038-45708817
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C20orf138", "dJ601O1.3", "WAP13" ]
[ "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Enzyme inhibitor" ]
null
null
null
1
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in some
41
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,172
6
ENSG00000168646
AXIN2
Axin 2
[ "Q9Y2T1" ]
17
65528563-65561648
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012283", "CAB017783" ]
[ "DKFZp781B0869", "MGC126582" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[ "Developmental protein" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[]
[]
Uncertain
Approved
null
49
null
null
Cluster 24: Non-specific - Transcription
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 32: Non-specific - Cell proliferation
Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
12,173
2
ENSG00000168653
NDUFS5
NADH:ubiquinone oxidoreductase subunit S5
[ "O43920" ]
1
39026318-39034636
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042582" ]
[ "CI-15k" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Supported
null
71
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 14: Neurons - Synaptic function
Cluster 37: Non-specific - mRNA processing
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,174
1
ENSG00000168658
VWA3B
Von Willebrand factor A domain containing 3B
[ "Q502W6" ]
2
98087116-98313299
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036700", "HPA036701" ]
[ "DKFZp686F2227", "MGC26733" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Intellectual disability", "Neurodegeneration" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 24: Non-specific - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
8
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,175
5
ENSG00000168661
ZNF30
Zinc finger protein 30
[ "P17039" ]
19
34926903-34945170
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA030400" ]
[ "DKFZp686N19164", "FLJ20562", "KOX28" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 15: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,176
7
ENSG00000168671
UGT3A2
UDP glycosyltransferase family 3 member A2
[ "Q3SY77" ]
5
36035021-36071358
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA059475" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Uncertain
null
null
Yes
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 49: Non-specific - Transcription
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in some
7
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,177
7
ENSG00000168675
LDLRAD4
Low density lipoprotein receptor class A domain containing 4
[ "O15165" ]
18
13217498-13652755
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047633", "HPA065246" ]
[ "C18orf1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Signal transduction inhibitor" ]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Approved
null
4
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 43: Hindbrain - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
6
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,179
3
ENSG00000168679
SLC16A4
Solute carrier family 16 member 4
[ "O15374" ]
1
110362851-110391082
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046986", "HPA060163" ]
[ "MCT4", "MCT5" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Symport", "Transport" ]
[]
[]
[ "Microtubules", "Cytosol" ]
[ "Cytokinetic bridge" ]
[]
[]
Approved
Approved
null
1
Yes
null
Cluster 18: Non-specific - Translation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 15: Kidney cancer - Membrane components
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 72: Kidney - Transmembrane transport
Tissue enriched
Detected in many
4
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
4
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,181
2
ENSG00000168685
IL7R
Interleukin 7 receptor
[ "P16871" ]
5
35852695-35879603
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010215", "HPA067550", "CAB080603" ]
[ "CD127", "IL7RA", "lnc-IL7R" ]
[ "Cancer-related genes", "CD markers", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[ "Cancer-related genes", "Disease variant", "SCID" ]
[ "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Supported
Supported
null
13
null
null
Cluster 27: T-cells - Unknown function
Cluster 48: Non-specific - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Group enriched
Detected in many
4
0
0
0
[]
[]
[]
12,182
4
ENSG00000168702
LRP1B
LDL receptor related protein 1B
[ "Q9NZR2" ]
2
140231423-142131016
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA069094", "HPA074788" ]
[ "LRP-DIT", "LRPDIT" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Endocytosis" ]
[ "Receptor" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
4
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 3: Rhabdoid - Membrane components
Cluster 109: Neurons - Neuronal signaling
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,184
7
ENSG00000168703
WFDC12
WAP four-disulfide core domain 12
[ "Q8WWY7" ]
20
45123425-45124465
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C20orf122", "dJ211D12.4", "WAP2" ]
[ "Predicted secreted proteins" ]
[]
[ "Antibiotic", "Antimicrobial", "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme inhibitor" ]
null
null
null
5
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
5
Cancer enriched
Detected in single
5
Group enriched
Detected in many
4
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,185
1
ENSG00000168710
AHCYL1
Adenosylhomocysteinase like 1
[ "O43865" ]
1
109984765-110023742
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042589" ]
[ "IRBIT", "PPP1R78", "XPVKONA" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "One-carbon metabolism" ]
[ "RNA-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
53
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
12,186
3
ENSG00000168724
DNAJC21
DnaJ heat shock protein family (Hsp40) member C21
[ "Q5F1R6" ]
5
34929559-34958964
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040789" ]
[ "DNAJA5", "GS3", "JJJ1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
11
null
null
Cluster 32: Basophils - Transcription
Cluster 45: Non-specific - Mixed function
Cluster 29: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,187
4
ENSG00000168734
PKIG
CAMP-dependent protein kinase inhibitor gamma
[ "Q9Y2B9" ]
20
44531785-44624247
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042703", "HPA063690" ]
[]
[ "Predicted intracellular proteins" ]
[]
[ "Protein kinase inhibitor" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Vesicles", "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
6
No
No
Cluster 18: Non-specific - Translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 55: Lymphoma - Immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Group enriched
Detected in many
11
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,188
8
ENSG00000168743
NPNT
Nephronectin
[ "Q6UXI9" ]
4
105894775-106004027
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA003711", "HPA050203" ]
[ "EGFL6L", "POEM" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion", "Differentiation" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm", "Cell Junctions", "Cytosol" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Developmental protein" ]
Approved
Supported
null
2
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 57: Podocytes - Glomerular filtration
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
12,189
6
ENSG00000168748
CA7
Carbonic anhydrase 7
[ "P43166" ]
16
66844414-66854153
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047237" ]
[]
[ "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Lyase" ]
[ "FDA approved drug targets" ]
[ "Cytosol" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 17: Intestine - Digestion
Tissue enriched
Detected in some
5
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,190
7
ENSG00000168754
FAM178B
Family with sequence similarity 178 member B
[ "Q8IXR5" ]
2
96875882-96986580
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042516", "HPA062110" ]
[ "LOC51252" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear speckles" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 3: Oligodendrocytes - Myelination
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Lung Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
12,191
9
ENSG00000168757
TSPY2
Testis specific protein Y-linked 2
[ "A6NKD2" ]
Y
6246223-6249019
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049384", "HPA067289" ]
[ "TSPYQ1" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Gonadal differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Supported
null
1
null
null
null
null
Cluster 20: Myeloma - Immune response
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
72
Cancer enriched
Detected in some
8
Cancer enriched
Detected in some
6
Group enriched
Detected in some
27
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,192
6
ENSG00000168758
SEMA4C
Semaphorin 4C
[ "Q9C0C4" ]
2
96859718-96870757
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011090" ]
[ "Semacl1", "Semaf", "SEMAI" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Approved
null
38
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 11: White matter - Signal transduction
Cluster 34: Testis cancer - Unknown function
Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,193
5
ENSG00000168763
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 3
[ "Q8NE01" ]
2
96816245-96835382
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016711" ]
[ "ACDP3" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Supported
null
78
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 25: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 17: Non-specific - RNA processing
Cluster 19: Skeletal muscle - Striated muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,194
1
ENSG00000168765
GSTM4
Glutathione S-transferase mu 4
[ "Q03013" ]
1
109656099-109665496
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048652", "HPA055972", "HPA055973" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Lyase", "Transferase" ]
[]
[ "Cytosol" ]
[ "Microtubules", "Cytokinetic bridge", "Primary cilium", "Primary cilium tip" ]
[]
[]
Approved
Approved
null
11
Yes
null
Cluster 22: Eosinophils - Transcription
Cluster 23: Choroid plexus - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in all
9
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,195
7
ENSG00000168769
TET2
Tet methylcytosine dioxygenase 2
[ "Q6N021" ]
4
105145875-105279816
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043135" ]
[ "FLJ20032", "KIAA1546" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Cell cycle" ]
[ "Chromatin regulator", "Dioxygenase", "DNA-binding", "Oxidoreductase" ]
[ "Cancer-related genes", "Disease variant", "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Supported
null
44
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 15: Bone marrow - Innate immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,196
2
ENSG00000168772
CXXC4
CXXC finger protein 4
[]
4
104468308-104494901
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA036600", "HPA036925" ]
[ "IDAX" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 10: Ciliated cells - Ion channel activity
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,197
1
ENSG00000168778
TCTN2
Tectonic family member 2
[ "Q96GX1" ]
12
123671110-123708399
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA039900" ]
[ "C12orf38", "FLJ12975", "JBTS24", "MKS8", "TECT2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Ciliopathy", "Joubert syndrome", "Meckel syndrome" ]
[ "Golgi apparatus", "Microtubules" ]
[ "Primary cilium transition zone" ]
[]
[]
Approved
Enhanced
null
41
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
12,198
4
ENSG00000168779
SHOX2
Short stature homeobox 2
[ "O60902" ]
3
158095905-158106420
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "OG12", "OG12X", "SHOT" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,199
4
ENSG00000168781
PPIP5K1
Diphosphoinositol pentakisphosphate kinase 1
[ "Q6PFW1" ]
15
43533462-43590208
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039380" ]
[ "HISPPD2A", "IPS1", "KIAA0377", "VIP1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 35: Non-specific - DNA binding
Cluster 58: Non-specific - Nuclear processes
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,200
8
ENSG00000168785
TSPAN5
Tetraspanin 5
[ "P62079" ]
4
98470367-98658611
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA079522" ]
[ "NET-4", "TM4SF9", "Tspan-5" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Approved
null
null
3
null
null
Cluster 1: T-cells - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
12,201
7
ENSG00000168792
ABHD15
Abhydrolase domain containing 15
[ "Q6UXT9" ]
17
29560547-29567037
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014470" ]
[]
[ "Predicted secreted proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Approved
null
13
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 39: Astrocytes - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
12,202
1
ENSG00000168795
ZBTB5
Zinc finger and BTB domain containing 5
[ "O15062" ]
9
37438102-37465450
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021521" ]
[ "KIAA0354" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Approved
null
13
null
null
Cluster 24: Non-specific - Transcription
Cluster 13: Oligodendrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 65: Non-specific - Cell growth & division
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
12,203
8
ENSG00000168802
CHTF8
Chromosome transmission fidelity factor 8
[ "P0CG13" ]
16
69118010-69132588
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CTF8", "FLJ20400" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA replication" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
null
null
7
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 68: Non-specific - Cell cycle regulation
Cluster 102: Non-specific - Mixed function
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,204
3
ENSG00000168803
ADAL
Adenosine deaminase like
[ "Q6DHV7" ]
15
43330672-43354569
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039879", "HPA048175", "HPA058795" ]
[]
[ "Predicted intracellular proteins" ]
[ "Nucleotide metabolism" ]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear speckles", "Vesicles" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 11: T-cells - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 58: Non-specific - Nuclear processes
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,205
9
ENSG00000168807
SNTB2
Syntrophin beta 2
[ "Q13425" ]
16
69187147-69309052
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001394" ]
[ "D16S2531E", "EST25263", "SNT2B2", "SNT3", "SNTL" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Calmodulin-binding" ]
[]
[ "Golgi apparatus", "Plasma membrane", "Centriolar satellite", "Basal body" ]
[ "Nucleoplasm", "Primary cilium transition zone" ]
[]
[]
Approved
null
null
28
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 68: Non-specific - Cell cycle regulation
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 47: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
12,207
1
ENSG00000168813
ZNF507
Zinc finger protein 507
[ "Q8TCN5" ]
19
32345594-32387667
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030964", "HPA049728" ]
[ "KIAA1084", "Zfp507" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 28: Oligodendrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,209
7
ENSG00000168824
NSG1
Neuronal vesicle trafficking associated 1
[ "P42857" ]
4
4348140-4419058
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "D4S234E", "NEEP21", "P21" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
32
null
null
Cluster 11: T-cells - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
0
0
0
[]
[]
[]
12,211
1
ENSG00000168826
ZBTB49
Zinc finger and BTB domain containing 49
[ "Q6ZSB9" ]
4
4290251-4321786
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024450" ]
[ "FLJ38559", "ZNF509" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Cell cycle", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Microtubules", "Cytosol" ]
[]
[]
Approved
Approved
null
19
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 55: Myocytes - Oxidative muscle function
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
12,212
3
ENSG00000168827
GFM1
G elongation factor mitochondrial 1
[ "Q96RP9" ]
3
158644527-158695581
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034764", "HPA034765", "HPA061405" ]
[ "EFGM", "EGF1", "GFM", "mtEF-G1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Elongation factor", "Hydrolase" ]
[ "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
33
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 31: Non-specific - Transcription
Cluster 63: Non-specific - Protein processing
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,213
2
ENSG00000168828
OR13J1
Olfactory receptor family 13 subfamily J member 1
[ "Q8NGT2" ]
9
35869463-35870401
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,214
4
ENSG00000168830
HTR1E
5-hydroxytryptamine receptor 1E
[ "P28566" ]
6
86937528-87016679
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA004931" ]
[ "5-HT1E" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Approved
null
3
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
7
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,215
3
ENSG00000168843
FSTL5
Follistatin like 5
[ "Q8N475" ]
4
161383897-162164004
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "DKFZp566D234", "KIAA1263" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in brain" ]
[ "No annotated function" ]
null
null
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 3: Rhabdoid - Membrane components
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
12
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in single
6
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,216
5
ENSG00000168872
DDX19A
DEAD-box helicase 19A
[ "Q9NUU7" ]
16
70346861-70373383
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045252", "HPA066668" ]
[ "DDX19L", "FLJ11126" ]
[ "Enzymes", "Predicted intracellular proteins", "Transporters" ]
[]
[ "Helicase", "Hydrolase", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Uncertain
Approved
null
10
null
null
Cluster 33: Non-specific - ATP binding
Cluster 21: Non-specific - Metabolism
Cluster 68: Non-specific - Cell cycle regulation
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,217
7
ENSG00000168874
ATOH8
Atonal bHLH transcription factor 8
[ "Q96SQ7" ]
2
85751344-85791383
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028406" ]
[ "bHLHa21", "FLJ14708", "HATH6" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
null
null
null
null
Cluster 20: Macrophages & Microglia - Immune response
Cluster 65: Non-specific - Unknown function
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
0
5
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,218
4
ENSG00000168875
SOX14
SRY-box transcription factor 14
[ "O95416" ]
3
137764315-137766334
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "SOX28" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[]
[]
[]
[]
null
null
null
14
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Rectum Adenocarcinoma" ]
[ "Rectum Adenocarcinoma" ]
12,219
6
ENSG00000168876
ANKRD49
Ankyrin repeat domain 49
[ "Q8WVL7" ]
11
94493979-94499578
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040273", "HPA048137" ]
[ "FGIF", "FLJ20189", "GBIF" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[]
[ "Nucleoplasm", "Nucleoli" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Approved
null
32
null
null
Cluster 20: Non-specific - DNA binding
Cluster 15: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
12,220
1
ENSG00000168878
SFTPB
Surfactant protein B
[ "P07988" ]
2
85657314-85668741
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002440", "HPA034820", "HPA062148" ]
[ "SFTP3", "SP-B" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Gaseous exchange" ]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
null
Enhanced
null
null
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 81: Alveolar cells - Lung function
Cluster 13: Lung - Secretion
Tissue enriched
Detected in many
30
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
6
Group enriched
Detected in some
22
Low immune cell specificity
Detected in single
null
2
0
2
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,221
9
ENSG00000168883
USP39
Ubiquitin specific peptidase 39
[ "Q53GS9" ]
2
85602856-85649283
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034823", "HPA077350" ]
[ "CGI-21", "SAD1", "SNRNP65" ]
[ "Enzymes", "Essential proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "mRNA processing", "mRNA splicing", "Ubl conjugation pathway" ]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
Supported
68
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,222
9
ENSG00000168890
TMEM150A
Transmembrane protein 150A
[ "Q86TG1" ]
2
85598547-85603196
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA019015" ]
[ "FLJ90024", "TM6P1", "TMEM150", "TTN1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
Cluster 25: Non-specific - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
12,225
1
ENSG00000168894
RNF181
Ring finger protein 181
[ "Q9P0P0" ]
2
85595725-85597708
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046112", "HPA062121" ]
[ "HSPC238" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
19
null
null
Cluster 29: Non-specific - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 8: Non-specific - Secretory pathway
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Lung Squamous Cell Carcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma" ]
12,226
6
ENSG00000168899
VAMP5
Vesicle associated membrane protein 5
[ "O95183" ]
2
85584431-85593406
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035082" ]
[]
[ "Predicted membrane proteins" ]
[ "Differentiation", "Myogenesis" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Approved
Supported
null
153
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 44: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
12,227
7
ENSG00000168903
BTNL3
Butyrophilin like 3
[ "Q6UXE8" ]
5
180988846-181006727
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "BTN9.1", "BTNLR" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 4: Neutrophils - Degranulation
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
65
Group enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
207
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
12,228
3
ENSG00000168904
LRRC28
Leucine rich repeat containing 28
[ "Q86X40" ]
15
99251362-99390729
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA039378", "HPA040784", "HPA066130" ]
[ "FLJ34269", "FLJ45242", "MGC24976" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Mitochondria" ]
[]
[]
Approved
Approved
null
3
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 53: Neurons - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,229
5
ENSG00000168907
PLA2G4F
Phospholipase A2 group IVF
[ "Q68DD2" ]
15
42139034-42156636
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042713", "HPA056752" ]
[ "PLA2G4F/Z" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Lipid degradation", "Lipid metabolism", "Phospholipid degradation", "Phospholipid metabolism" ]
[ "Hydrolase" ]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
null
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 81: Alveolar cells - Lung function
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in many
6
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
6
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,231
2
ENSG00000168913
ENHO
Energy homeostasis associated
[ "Q6UWT2" ]
9
34521043-34522990
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042575" ]
[ "C9orf165", "UNQ470" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in brain" ]
[ "No annotated function" ]
null
Approved
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in many
22
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
4
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
8
2
0
2
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
12,232
1
ENSG00000168916
ZNF608
Zinc finger protein 608
[ "Q9ULD9" ]
5
124636913-124748807
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA005545", "HPA076984" ]
[ "DKFZp434M098", "KIAA1281", "NY-REN-36" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Approved
Approved
null
8
null
null
Cluster 32: Basophils - Transcription
Cluster 11: White matter - Signal transduction
Cluster 6: Leukemia - Signal transduction
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
12,233
4
ENSG00000168917
SLC35G2
Solute carrier family 35 member G2
[ "Q8TBE7" ]
3
136818647-136855888
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052054", "HPA064728" ]
[ "DKFZp564K2464", "MGC3295", "TMEM22" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Approved
null
8
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 64: Connective tissue cells - ECM organization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 36: Brain & Liver - Signaling
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
5
0
5
[ "Rectum Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
12,234
3
ENSG00000168918
INPP5D
Inositol polyphosphate-5-phosphatase D
[ "Q92835" ]
2
233059967-233207903
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016300", "HPA070455" ]
[ "hp51CN", "SHIP", "SHIP1" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Immunity", "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
24
No
No
Cluster 40: Monocytes - Innate immune response
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 102: Non-specific - Mixed function
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
10
Low immune cell specificity
Detected in all
null
1
0
1
[ "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
12,235
7
ENSG00000168924
LETM1
Leucine zipper and EF-hand containing transmembrane protein 1
[ "O95202" ]
4
1811479-1856156
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011029", "HPA011100" ]
[ "Mdm38", "SLC55A1." ]
[ "Essential proteins", "Human disease related genes", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Calcium transport", "Ion transport", "Potassium transport", "Transport" ]
[]
[ "Disease variant", "Neurodegeneration" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Supported
null
40
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,236
8
ENSG00000168928
CTRB2
Chymotrypsinogen B2
[ "Q6GPI1" ]
16
75204103-75207161
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[]
[ "Enzymes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Digestion" ]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
null
null
null
null
null
null
null
null
Cluster 15: Kidney cancer - Membrane components
Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion
Cluster 8: Pancreas - Proteolysis
Tissue enriched
Detected in many
2,546
Not detected
Not detected
null
Cancer enriched
Detected in some
2,928
Cell type enriched
Detected in some
104
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,238
6
ENSG00000168936
TMEM129
Transmembrane protein 129, E3 ubiquitin ligase
[ "A0AVI4" ]
4
1715952-1721358
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "D4S2561E" ]
[ "Enzymes", "Predicted membrane proteins" ]
[ "Ubl conjugation pathway", "Unfolded protein response" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
2
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,240
7
ENSG00000168938
PPIC
Peptidylprolyl isomerase C
[ "P45877" ]
5
123023250-123036725
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039163" ]
[ "CYPC" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Isomerase", "Rotamase" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Approved
null
8
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 15: Kidney cancer - Membrane components
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe" ]
12,241
7
ENSG00000168939
SPRY3
Sprouty RTK signaling antagonist 3
[ "O43610" ]
X
155612572-155782459
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB013505" ]
[ "HSPRY3" ]
[ "Predicted membrane proteins" ]
[ "Neurogenesis" ]
[]
[]
[ "Cytosol" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
22
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 7: Liver cancer - Metabolism
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,242
3
ENSG00000168944
CEP120
Centrosomal protein 120
[ "Q8N960" ]
5
123344890-123423592
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028823", "HPA051556" ]
[ "CCDC100", "FLJ36090" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant", "Joubert syndrome" ]
[ "Microtubules", "Flagellar centriole", "Annulus" ]
[ "Mitotic spindle", "Cytosol", "Perinuclear theca", "Mid piece" ]
[]
[]
Uncertain
Uncertain
null
12
Yes
null
Cluster 42: Non-specific - Vesicular transport
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
12,243
5
ENSG00000168952
STXBP6
Syntaxin binding protein 6
[ "Q8NFX7" ]
14
24809454-25050147
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003552", "HPA074869" ]
[ "amisyn", "HSPC156" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
3
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 104: Brain endothelial cells - Blood brain barrier
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Rectum Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,244
9
ENSG00000168955
TM4SF20
Transmembrane 4 L six family member 20
[ "Q53R12" ]
2
227362038-227381995
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051838", "HPA063184", "HPA065531" ]
[ "FLJ22800", "TCCE518" ]
[ "Disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[ "Autism spectrum disorder" ]
[ "Plasma membrane", "Focal adhesion sites" ]
[]
[]
[]
Supported
Uncertain
null
6
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
76
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
5
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,245
3
ENSG00000168958
MFF
Mitochondrial fission factor
[ "Q9GZY8" ]
2
227325151-227357833
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA010968", "HPA074625" ]
[ "C2orf33", "GL004" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Principal piece" ]
[]
[]
Supported
Enhanced
null
13
No
No
Cluster 22: Eosinophils - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in all
5
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,246
3
ENSG00000168961
LGALS9
Galectin 9
[ "O00182" ]
17
27629798-27649560
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046876", "HPA047218", "CAB080347" ]
[ "LGALS9A" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Chemotaxis", "Immunity" ]
[]
[]
[ "Cytosol" ]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
Supported
Approved
null
64
null
null
Cluster 25: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 34: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
12,248
5
ENSG00000168970
JMJD7-PLA2G4B
JMJD7-PLA2G4B readthrough
[]
15
41828095-41848155
Evidence at protein level
Evidence at protein level
null
null
[ "HPA005726" ]
[]
[ "Predicted intracellular proteins", "RAS pathway related proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 6: Non-specific - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 15: Non-specific - Protein processing
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,249
7
ENSG00000168993
CPLX1
Complexin 1
[ "O14810" ]
4
784957-826129
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071191", "HPA074390" ]
[ "CPX-I" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Exocytosis", "Neurotransmitter transport", "Transport" ]
[]
[ "Disease variant", "Epilepsy" ]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Supported
null
4
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
12,250
8
ENSG00000168994
PXDC1
PX domain containing 1
[ "Q5TGL8" ]
6
3722614-3751713
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA019246" ]
[ "C6orf145" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
null
null
3
null
null
null
Cluster 8: Immune cells - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Stomach Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Stomach Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,251
5
ENSG00000169016
E2F6
E2F transcription factor 6
[ "O75461" ]
2
11444375-11466177
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA075185" ]
[ "E2F-6" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Cell cycle", "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
92
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 17: Non-specific - RNA processing
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Immune cell enriched
Detected in single
16
2
2
1
[ "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,254
9
ENSG00000169018
FEM1B
Fem-1 homolog B
[ "Q9UK73" ]
15
68277745-68295862
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041920", "HPA042192" ]
[]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
28
null
null
Cluster 33: Non-specific - ATP binding
Cluster 34: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,255
1
ENSG00000169019
COMMD8
COMM domain containing 8
[ "Q9NX08" ]
4
47450787-47463702
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035887" ]
[ "FLJ20502" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
61
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 97: Non-specific - Cellular respiration
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,256
3