ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000170037
CNTROB
Centrobin, centriole duplication and spindle assembly protein
[ "Q8N137" ]
17
7932101-7949920
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023319", "HPA023320", "HPA023321", "HPA023325" ]
[ "LIP8", "PP1221" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[]
[]
[ "Centrosome", "Basal body", "Flagellar centriole" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
20
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 6: Non-specific - Immune response
Cluster 42: Non-specific - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,483
5
ENSG00000170043
TRAPPC1
Trafficking protein particle complex subunit 1
[ "Q9Y5R8" ]
17
7930345-7932123
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052398" ]
[ "BET5", "MUM2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "ER-Golgi transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
62
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 38: Sub-cortical - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 47: Platelets - Hemostasis
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
12,484
4
ENSG00000170049
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3
[ "O43448" ]
17
7921859-7929856
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA077993" ]
[ "AKR6A9", "KCNA3B" ]
[ "Predicted intracellular proteins" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Oxidoreductase", "Voltage-gated channel" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
null
null
4
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,486
8
ENSG00000170054
SERPINA9
Serpin family A member 9
[ "Q86WD7" ]
14
94462717-94479689
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "GCET1", "SERPINA11b" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Enzyme inhibitor" ]
null
null
null
null
null
null
null
null
Cluster 46: Lymphoma - Humoral immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 18: Lymphoid tissue - Immune response
Tissue enriched
Detected in some
18
Cancer enriched
Detected in single
43
Group enriched
Detected in some
4
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,487
6
ENSG00000170074
FAM153A
Family with sequence similarity 153 member A
[ "Q9UHL3" ]
5
177707981-177784435
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042585", "HPA044022", "HPA046691", "HPA052337", "HPA055498" ]
[ "NY-REN-7" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in many
5
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
12,488
9
ENSG00000170075
GPR37L1
G protein-coupled receptor 37 like 1
[ "O60883" ]
1
202122886-202133592
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061629", "HPA064454" ]
[ "ETBR-LP-2" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Nucleoplasm", "Cell Junctions" ]
[ "Vesicles", "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
49
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
9
Not detected
Not detected
null
Cancer enriched
Detected in some
45
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,489
8
ENSG00000170088
TMEM192
Transmembrane protein 192
[ "Q8IY95" ]
4
165070608-165208549
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014717", "HPA024110" ]
[ "FLJ38482" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Endosomes", "Lysosomes" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Enhanced
null
27
null
null
Cluster 30: Non-specific - DNA binding
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
12,491
2
ENSG00000170091
NSG2
Neuronal vesicle trafficking associated 2
[ "Q9Y328" ]
5
174045706-174243501
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046531", "HPA056191" ]
[ "CALY3", "HMP19" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Enhanced
Enhanced
null
8
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
12
Group enriched
Detected in some
5
Cancer enriched
Detected in some
8
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,492
8
ENSG00000170092
SPDYE5
Speedy/RINGO cell cycle regulator family member E5
[ "A6NIY4" ]
7
75492320-75504316
Evidence at protein level
Evidence at protein level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA051750" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 39: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in single
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,493
2
ENSG00000170099
SERPINA6
Serpin family A member 6
[ "P08185" ]
14
94304248-94323389
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA017864" ]
[ "CBG" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Transport" ]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Transport" ]
null
Approved
null
2
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
18
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
10
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,494
9
ENSG00000170100
ZNF778
Zinc finger protein 778
[ "Q96MU6" ]
16
89217703-89237141
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052057", "HPA057151" ]
[ "FLJ31875" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Uncertain
null
1
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 35: Non-specific - DNA binding
Cluster 68: Non-specific - Cell cycle regulation
Cluster 47: Platelets - Hemostasis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
5
Immune cell enhanced
Detected in many
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,495
8
ENSG00000170113
NIPA1
NIPA magnesium transporter 1
[ "Q7RTP0" ]
15
22773063-22829789
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA023269" ]
[ "MGC35570", "SLC57A1", "SPG6" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration" ]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 45: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 102: Non-specific - Mixed function
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,496
3
ENSG00000170122
FOXD4
Forkhead box D4
[ "Q12950" ]
9
116231-118417
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012836" ]
[ "FKHL9", "FOXD4a", "FREAC5" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
23
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 71: Cerebellum - Nervous system development
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,497
5
ENSG00000170128
GPR25
G protein-coupled receptor 25
[ "O00155" ]
1
200872981-200874178
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
27
null
null
Cluster 16: Non-specific - Cell proliferation
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 5: Spleen - Immune response
Tissue enriched
Detected in single
4
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
12,498
3
ENSG00000170142
UBE2E1
Ubiquitin conjugating enzyme E2 E1
[ "P51965" ]
3
23805955-23891640
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030445", "CAB073413", "CAB080048" ]
[ "UbcH6" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
68
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 55: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,499
4
ENSG00000170144
HNRNPA3
Heterogeneous nuclear ribonucleoprotein A3
[ "P51991" ]
2
177212694-177223959
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001666", "HPA005812", "HPA066381" ]
[ "HNRPA3" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
113
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 17: Non-specific - RNA processing
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,500
9
ENSG00000170145
SIK2
Salt inducible kinase 2
[ "Q9H0K1" ]
11
111602449-111730855
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016026", "HPA071049" ]
[ "DKFZp434K1115", "KIAA0781", "LOH11CR1I", "QIK", "SNF1LK2" ]
[ "Enzymes", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[ "Nuclear speckles", "Intermediate filaments", "Cytosol" ]
[]
[]
Approved
Approved
null
25
null
null
Cluster 25: Non-specific - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 89: Adipocytes - Lipid metabolism
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,501
3
ENSG00000170153
RNF150
Ring finger protein 150
[ "Q9ULK6" ]
4
140859807-141212877
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037987" ]
[ "KIAA1214" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
null
Uncertain
null
null
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Cancer enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Breast Invasive Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Breast Invasive Carcinoma", "Kidney Chromophobe" ]
12,502
6
ENSG00000170160
CCDC144A
Coiled-coil domain containing 144A
[ "A2RUR9" ]
17
16689537-16777881
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA022996", "HPA023009", "HPA047851", "HPA066260" ]
[ "FLJ43983", "KIAA0565" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Cell Junctions" ]
[]
[]
Approved
Enhanced
null
1
null
null
Cluster 11: T-cells - Unknown function
Cluster 9: Non-specific - Receptor signaling
Cluster 51: Myeloma - Immunoglobulins
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 32: Retina & Lymphoid tissues - Signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
12,503
7
ENSG00000170166
HOXD4
Homeobox D4
[ "P09016" ]
2
176151550-176153226
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054383", "HPA070349" ]
[ "HOX4", "HOX4B" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cell Junctions" ]
[]
[]
Supported
Approved
null
2
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
12,505
7
ENSG00000170175
CHRNB1
Cholinergic receptor nicotinic beta 1 subunit
[ "P11230" ]
17
7445061-7457710
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005822", "CAB011200" ]
[ "CHRNB" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "Congenital myasthenic syndrome", "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 8: Immune cells - Immune response
Cluster 33: Sarcoma - Muscle contraction
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
12,506
7
ENSG00000170178
HOXD12
Homeobox D12
[ "P35452" ]
2
176099795-176102489
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059444" ]
[ "HOX4H" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
null
Cluster 12: Bone cancer - Neuronal signaling
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,507
2
ENSG00000170180
GYPA
Glycophorin A (MNS blood group)
[ "P02724" ]
4
144109303-144140751
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002658", "HPA014811" ]
[ "CD235a", "GPA", "MN", "MNS" ]
[ "Blood group antigen proteins", "CD markers", "Predicted membrane proteins", "Transporters" ]
[ "Host-virus interaction" ]
[ "Blood group antigen", "Host cell receptor for virus entry", "Receptor" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
27
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in some
38
Cancer enriched
Detected in some
18
Not detected
Not detected
null
Group enriched
Detected in some
36
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,508
9
ENSG00000170185
USP38
Ubiquitin specific peptidase 38
[ "Q8NB14" ]
4
143184917-143223874
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036990", "HPA047948" ]
[ "HP43.8KD", "KIAA1891" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome", "Cytosol" ]
[]
[]
Approved
Uncertain
null
7
null
null
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,509
1
ENSG00000170190
SLC16A5
Solute carrier family 16 member 5
[ "O15375" ]
17
75087727-75106162
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MCT5", "MCT6" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Symport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
null
null
2
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 26: Kidney & Intestine - Metabolism
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
0
0
0
[]
[]
[]
12,510
3
ENSG00000170209
ANKK1
Ankyrin repeat and kinase domain containing 1
[ "Q8NFD2" ]
11
113387779-113400416
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012813" ]
[ "X-kinase" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
13
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,512
8
ENSG00000170214
ADRA1B
Adrenoceptor alpha 1B
[ "P35368" ]
5
159865080-159973012
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA074416" ]
[]
[ "Cancer-related genes", "FDA approved drug targets", "G-protein coupled receptors", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[]
[]
[]
Supported
null
null
3
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 15: Kidney cancer - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Thyroid Carcinoma" ]
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Thyroid Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,513
5
ENSG00000170222
ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
[ "Q3LIE5" ]
17
10697594-10711558
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA023265", "HPA023820", "HPA069342" ]
[ "C17orf48", "MDS006" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 55: Non-specific - Transcription
Cluster 42: Non-specific - Unknown function
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,514
1
ENSG00000170231
FABP6
Fatty acid binding protein 6
[ "P51161" ]
5
160187367-160238735
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012601", "CAB024713" ]
[ "I-15P", "I-BABP", "I-BALB", "I-BAP", "ILBP", "ILBP3", "ILLBP" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid transport", "Transport" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Transport" ]
null
Enhanced
null
null
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in many
84
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
21
Not detected in immune cells
Not detected
null
6
2
5
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,515
6
ENSG00000170234
PWWP2A
PWWP domain containing 2A
[ "Q96N64" ]
5
160061801-160119450
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046733", "HPA058233" ]
[ "KIAA1935" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm" ]
[ "Focal adhesion sites" ]
[]
[]
Supported
null
null
19
null
null
Cluster 14: Non-specific - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,516
1
ENSG00000170236
USP50
Ubiquitin specific peptidase 50
[ "Q70EL3" ]
15
50494018-50546708
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA039470" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Cell cycle" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
null
null
null
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
5
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,517
6
ENSG00000170242
USP47
Ubiquitin specific peptidase 47
[ "Q96K76" ]
11
11841423-11961887
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029286", "HPA029289" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Intermediate filaments" ]
[ "Vesicles" ]
[]
[]
Approved
Supported
null
20
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 55: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,518
1
ENSG00000170248
PDCD6IP
Programmed cell death 6 interacting protein
[ "Q8WUM4" ]
3
33798571-33869707
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011905", "CAB016212", "HPA051110", "HPA051604" ]
[ "AIP1", "Alix", "Hp95" ]
[ "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Cell cycle", "Cell division", "Host-virus interaction", "Protein transport", "Transport" ]
[]
[ "Intellectual disability", "Primary microcephaly" ]
[ "Vesicles" ]
[ "Centrosome" ]
[ "Intracellular and membrane" ]
[ "Transport" ]
Approved
Supported
null
78
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 49: Hindbrain - Mixed function
Cluster 8: Non-specific - Basic cellular processes
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,519
1
ENSG00000170255
MRGPRX1
MAS related GPR family member X1
[ "Q96LB2" ]
11
18933499-18939414
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[]
[ "MRGX1" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Acute phase" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 3: Rhabdoid - Membrane components
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
null
Not detected
Not detected
null
Cancer enriched
Detected in some
15
Not detected
Not detected
null
Group enriched
Detected in some
17
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,520
4
ENSG00000170260
ZNF212
Zinc finger protein 212
[ "Q9UDV6" ]
7
149239651-149255606
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049807", "HPA054178" ]
[ "C2H2-150" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
21
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 25: Non-specific - Transcription
Cluster 39: Non-specific - Transcription
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
12,521
1
ENSG00000170262
MRAP
Melanocortin 2 receptor accessory protein
[ "Q8TCY5" ]
21
32291813-32314784
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011024", "HPA011093" ]
[ "B27", "C21orf61", "FALP" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[ "Vesicles" ]
[]
[]
Supported
Uncertain
null
5
null
null
null
Cluster 8: Immune cells - Immune response
Cluster 18: Liver cancer - Metabolism
Cluster 89: Adipocytes - Lipid metabolism
Cluster 4: Adrenal gland - Steroid metabolism
Group enriched
Detected in many
6
Not detected
Not detected
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,522
9
ENSG00000170264
FAM161A
FAM161 centrosomal protein A
[ "Q3B820" ]
2
61824848-61854143
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA032119", "HPA064830" ]
[ "FLJ13305", "RP28" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation", "Sensory transduction", "Vision" ]
[]
[ "Ciliopathy", "Disease variant", "Retinitis pigmentosa" ]
[ "Centrosome", "Basal body", "Flagellar centriole" ]
[ "Nucleoplasm", "Golgi apparatus", "Cytosol" ]
[]
[]
Supported
Approved
null
125
null
Yes
null
Cluster 23: Choroid plexus - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,523
8
ENSG00000170265
ZNF282
Zinc finger protein 282
[ "Q9UDV7" ]
7
149195546-149226238
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024374" ]
[ "HUB1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Supported
null
3
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 15: Non-specific - Transcription
Cluster 39: Non-specific - Transcription
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in some
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,524
2
ENSG00000170266
GLB1
Galactosidase beta 1
[ "P16278" ]
3
32996609-33097202
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB008382", "HPA040610", "HPA069503" ]
[ "EBP", "ELNR1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Glycosidase", "Hydrolase" ]
[ "Disease variant", "Gangliosidosis", "Mucopolysaccharidosis" ]
[ "Vesicles" ]
[ "Golgi apparatus" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Supported
Enhanced
null
17
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 21: Non-specific - Metabolism
Cluster 34: Testis cancer - Unknown function
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,525
9
ENSG00000170270
GON7
GON7 subunit of KEOPS complex
[ "Q9BXV9" ]
14
93202894-93207065
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051832" ]
[ "C14orf142" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Nucleoplasm", "Nucleoli rim" ]
[]
[]
[]
Supported
Approved
null
13
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 17: Choroid plexus - Cilium
Cluster 30: Non-specific - Gene expression regulation
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,526
2
ENSG00000170271
FAXDC2
Fatty acid hydroxylase domain containing 2
[ "Q96IV6" ]
5
154818492-154859252
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C5orf4", "FLJ13758" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
28
null
null
Cluster 20: Non-specific - DNA binding
Cluster 11: White matter - Signal transduction
Cluster 47: Leukemia - Hemostasis
Cluster 47: Platelets - Hemostasis
Cluster 69: Parathyroid gland - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
12,527
2
ENSG00000170275
CRTAP
Cartilage associated protein
[ "O75718" ]
3
33114014-33147773
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043598", "HPA044150" ]
[ "CASP", "LEPREL3", "P3H5" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant", "Dwarfism", "Osteogenesis imperfecta" ]
[ "Intermediate filaments", "Actin filaments", "Cytosol" ]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Approved
null
24
null
null
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 19: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Uterine Corpus Endometrial Carcinoma" ]
12,528
4
ENSG00000170276
HSPB2
Heat shock protein family B (small) member 2
[ "Q16082" ]
11
111912734-111914093
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA079414" ]
[ "Hs.78846", "MKBP" ]
[ "Predicted intracellular proteins" ]
[ "Stress response" ]
[]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
35
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 64: Connective tissue cells - ECM organization
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
12,529
4
ENSG00000170279
C7orf33
Chromosome 7 open reading frame 33
[ "Q8WU49" ]
7
148590766-148615860
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA047587" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Acrosome", "Equatorial segment" ]
[]
[]
[]
Approved
null
null
1
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in single
6
Cancer enriched
Detected in single
6
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,530
9
ENSG00000170289
CNGB3
Cyclic nucleotide gated channel subunit beta 3
[ "Q9NQW8" ]
8
86553977-86743675
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA057244" ]
[ "ACHM1", "ACHM3", "RMCH" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Sensory transduction", "Transport", "Vision" ]
[ "Ion channel", "Ligand-gated ion channel" ]
[ "Disease variant", "Stargardt disease" ]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 31: Non-specific - Transcription
Cluster 10: Ciliated cells - Ion channel activity
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 32: Retina & Lymphoid tissues - Signaling
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in many
12
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,531
1
ENSG00000170290
SLN
Sarcolipin
[ "O00631" ]
11
107707378-107719693
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB011628" ]
[ "MGC12301", "MGC125854", "MGC125855" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Microtubules" ]
[]
[]
[]
Approved
null
null
6
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 5: Rhabdoid - Unknown function
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
6
Cancer enriched
Detected in some
35
Group enriched
Detected in many
6
Group enriched
Detected in some
17
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,532
4
ENSG00000170291
ELP5
Elongator acetyltransferase complex subunit 5
[ "Q8TE02" ]
17
7251416-7259940
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023279", "HPA052411" ]
[ "C17orf81", "DERP6" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[ "Intracellular and membrane" ]
[ "Other" ]
Supported
Uncertain
null
10
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 19: Astrocytes - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
9
Low immune cell specificity
Detected in all
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
12,533
8
ENSG00000170293
CMTM8
CKLF like MARVEL transmembrane domain containing 8
[ "Q8IZV2" ]
3
32238679-32370321
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055077", "HPA073258" ]
[ "CKLFSF8" ]
[ "Predicted membrane proteins" ]
[ "Chemotaxis" ]
[ "Cytokine" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
9
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 47: Endothelial cells - Vasculature
Cluster 6: Leukemia - Signal transduction
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,534
2
ENSG00000170298
LGALS9B
Galectin 9B
[ "Q3B8N2" ]
17
20449395-20467539
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046876", "HPA047218" ]
[]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Uncertain
Approved
null
9
null
null
Cluster 15: NK-cells - Unknown function
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 68: Foveolar cells - Mucosal defense
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
4
Immune cell enriched
Detected in single
17
0
0
0
[]
[]
[]
12,536
8
ENSG00000170310
STX8
Syntaxin 8
[ "Q9UNK0" ]
17
9250471-9576591
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001540" ]
[ "CARB" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transport" ]
[]
[]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
144
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in all
4
Low immune cell specificity
Detected in all
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
12,537
5
ENSG00000170312
CDK1
Cyclin dependent kinase 1
[ "P06493" ]
10
60778331-60794852
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003387", "CAB003799", "CAB079974" ]
[ "CDC2", "CDC28A" ]
[ "Cancer-related genes", "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Apoptosis", "Biological rhythms", "Cell cycle", "Cell division", "Host-virus interaction", "Mitosis" ]
[ "Host cell receptor for virus entry", "Kinase", "Receptor", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Acrosome", "Perinuclear theca", "Connecting piece", "Flagellar centriole" ]
[]
[]
Supported
Enhanced
null
168
null
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 12: Non-specific - Vasculature
Cluster 52: Non-specific - Mitochondria
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
6
6
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,538
9
ENSG00000170315
UBB
Ubiquitin B
[ "P0CG47" ]
17
16380798-16382745
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013048", "HPA041344", "HPA049132" ]
[ "FLJ25987", "MGC8385" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Acrosome", "Equatorial segment" ]
[]
[]
Uncertain
Supported
null
89
null
null
Cluster 41: Basophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,539
1
ENSG00000170322
NFRKB
Nuclear factor related to kappaB binding protein
[ "Q6P4R8" ]
11
129863636-129895590
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007082", "HPA007128" ]
[ "DKFZp547B2013", "INO80G" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA recombination", "DNA repair", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
32
Yes
No
Cluster 42: Non-specific - Vesicular transport
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 24: Non-specific - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Rectum Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Rectum Adenocarcinoma" ]
12,540
2
ENSG00000170324
FRMPD2
FERM and PDZ domain containing 2
[ "Q68DX3" ]
10
48153088-48274696
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046389", "HPA052208" ]
[ "MGC35285", "PDZD5C", "PDZK5C" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus", "Vesicles" ]
[]
[]
[]
Uncertain
null
null
null
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
8
Cancer enriched
Detected in single
5
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,542
1
ENSG00000170325
PRDM10
PR/SET domain 10
[ "Q9NQV6" ]
11
129899706-130002835
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026997", "HPA061749" ]
[ "KIAA1231", "MGC131802", "PFM7" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Nucleoli fibrillar center", "Vesicles" ]
[]
[]
Supported
Approved
null
2
null
null
Cluster 22: Eosinophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 46: Lymphoma - Humoral immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,543
1
ENSG00000170340
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
[ "Q9NY97" ]
2
62196115-62224731
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005997" ]
[ "B3GN-T1", "B3GN-T2", "B3GNT-2", "B3GNT1", "BETA3GNT" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
15
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 33: Neurons - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 103: Non-specific - Basic cellular processes
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,544
4
ENSG00000170345
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
[ "P01100" ]
14
75278826-75282230
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018531", "CAB080210" ]
[ "AP-1", "c-fos" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
122
Yes
No
Cluster 21: Neutrophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 15: Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
0
0
0
[]
[]
[]
12,545
2
ENSG00000170348
TMED10
Transmembrane p24 trafficking protein 10
[ "P49755" ]
14
75131469-75176612
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB034442", "CAB037251", "HPA047139", "HPA050539" ]
[ "p23", "P24(DELTA)", "p24d1", "p24delta1", "TMP21" ]
[ "Essential proteins", "Predicted membrane proteins", "Transporters" ]
[ "ER-Golgi transport", "Protein transport", "Transport" ]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Enhanced
null
171
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 39: Astrocytes - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 8: Non-specific - Secretory pathway
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
12,546
6
ENSG00000170364
SETMAR
SET domain and mariner transposase fusion gene
[ "Q53H47" ]
3
4303332-4317265
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA057999" ]
[ "metnase" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Chromatin regulator", "DNA-binding", "Endonuclease", "Hydrolase", "Methyltransferase", "Multifunctional enzyme", "Nuclease", "Transferase" ]
[]
[ "Nucleoli" ]
[]
[]
[]
Supported
null
null
6
null
null
Cluster 24: Non-specific - Transcription
Cluster 11: White matter - Signal transduction
Cluster 8: Non-specific - Basic cellular processes
Cluster 89: Adipocytes - Lipid metabolism
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,547
7
ENSG00000170365
SMAD1
SMAD family member 1
[ "Q15797" ]
4
145481194-145559176
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005389" ]
[ "JV4-1", "MADH1", "MADR1" ]
[ "Cancer-related genes", "Disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
61
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 46: Lymphoma - Humoral immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
12,548
4
ENSG00000170367
CST5
Cystatin D
[ "P28325" ]
20
23875934-23879748
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB024944", "HPA061449" ]
[]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Thiol protease inhibitor" ]
[]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme inhibitor" ]
null
Enhanced
null
15
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 82: Salivary gland - Secretion
Tissue enriched
Detected in some
956
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
9
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,549
2
ENSG00000170369
CST2
Cystatin SA
[ "P09228" ]
20
23823769-23826729
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB024963", "HPA043706", "HPA044763" ]
[]
[ "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Thiol protease inhibitor" ]
[]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme inhibitor" ]
null
Enhanced
null
12
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 82: Salivary gland - Secretion
Tissue enriched
Detected in some
635
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
14
Not detected in immune cells
Not detected
null
4
0
4
[]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
12,550
9
ENSG00000170370
EMX2
Empty spiracles homeobox 2
[ "Q04743" ]
10
117542445-117549546
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003497", "HPA065294" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
Supported
2
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
5
Group enriched
Detected in many
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
2
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
12,551
7
ENSG00000170374
SP7
Sp7 transcription factor
[ "Q8TDD2" ]
12
53326575-53345315
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063202" ]
[ "osterix", "OSX" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Osteogenesis imperfecta" ]
[]
[]
[]
[]
null
Enhanced
null
13
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 32: Non-specific - Cell proliferation
Cluster 79: Photoreceptor cells - Phototransduction
null
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,553
9
ENSG00000170379
TCAF2
TRPM8 channel associated factor 2
[ "A6NFQ2" ]
7
143620952-143730410
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038756", "HPA038758" ]
[ "FAM115C", "FAM139A", "FLJ40722", "GATD9B" ]
[ "Predicted intracellular proteins" ]
[ "Transport" ]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[]
[]
[]
Supported
Uncertain
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 37: Neurons - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 105: Non-specific - Mixed function
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
12,554
2
ENSG00000170381
SEMA3E
Semaphorin 3E
[ "O15041" ]
7
83363238-83649139
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029419", "HPA063804" ]
[ "coll-5", "KIAA0331", "M-SemaK", "SEMAH" ]
[ "Human disease related genes", "Predicted secreted proteins" ]
[ "Angiogenesis", "Differentiation", "Neurogenesis" ]
[ "Developmental protein" ]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[ "Secreted in other tissues" ]
[ "Developmental protein" ]
Approved
Uncertain
null
1
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
12,555
3
ENSG00000170382
LRRN2
Leucine rich repeat neuronal 2
[ "O75325" ]
1
204617170-204685738
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA029124" ]
[ "FIGLER7", "GAC1", "LRANK1", "LRRN5" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 109: Neurons - Neuronal signaling
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
7
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,556
2
ENSG00000170385
SLC30A1
Solute carrier family 30 member 1
[ "Q9Y6M5" ]
1
211571568-211579161
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015275", "HPA049000" ]
[ "ZNT1", "ZRC1" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Ion transport", "Transport", "Zinc transport" ]
[]
[]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Supported
Uncertain
null
21
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 42: Choroid plexus - Mitochondria
Cluster 47: Leukemia - Hemostasis
Cluster 104: Brain endothelial cells - Blood brain barrier
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,557
9
ENSG00000170396
ZNF804A
Zinc finger protein 804A
[ "Q7Z570" ]
2
184598529-184939492
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA029195" ]
[ "C2orf10" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 3: Rhabdoid - Membrane components
Cluster 109: Neurons - Neuronal signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in single
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
12,559
3
ENSG00000170417
TMEM182
Transmembrane protein 182
[ "Q6ZP80" ]
2
102736905-103019900
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA045861" ]
[ "FLJ30294" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Myogenesis" ]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
null
null
17
null
null
Cluster 24: Non-specific - Transcription
Cluster 43: Hindbrain - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 41: Striated muscle - Muscle contraction
Group enriched
Detected in many
23
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,561
6
ENSG00000170419
VSTM2A
V-set and transmembrane domain containing 2A
[ "Q8TAG5" ]
7
54542325-54571080
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MGC33530", "VSTM2" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[ "Differentiation" ]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
null
null
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
5
Group enriched
Detected in some
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,562
4
ENSG00000170421
KRT8
Keratin 8
[ "P05787" ]
12
52897187-52949954
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000131", "CAB001696", "HPA049866" ]
[ "CARD2", "CK-8", "CK8", "CYK8", "K2C8", "K8", "KO" ]
[ "Cancer-related genes", "Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Intermediate filaments" ]
[]
[]
[]
Supported
Enhanced
null
74
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 44: Non-specific - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,563
5
ENSG00000170423
KRT78
Keratin 78
[ "Q8N1N4" ]
12
52837804-52849092
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039724" ]
[ "K5B" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
18
null
null
null
null
Cluster 30: Non-specific - Gene expression regulation
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
5
Cell type enriched
Detected in some
30
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,564
9
ENSG00000170425
ADORA2B
Adenosine A2b receptor
[ "P29275" ]
17
15945130-15975746
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA073747" ]
[]
[ "FDA approved drug targets", "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Vesicles", "Primary cilium tip" ]
[]
[]
Supported
null
null
28
null
Yes
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 49: HMC-1 - Innate immune response
Cluster 26: Keratinocytes - Keratinization
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,565
5
ENSG00000170426
SDR9C7
Short chain dehydrogenase/reductase family 9C member 7
[ "Q8NEX9" ]
12
56923133-56934408
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "RDHS", "SDR-O" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[ "Disease variant", "Ichthyosis" ]
[]
[]
[]
[]
null
null
null
22
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,566
3
ENSG00000170430
MGMT
O-6-methylguanine-DNA methyltransferase
[ "P16455" ]
10
129467190-129770983
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002786", "HPA032135", "HPA032136", "HPA069497", "CAB069881" ]
[]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "DNA-binding", "Methyltransferase", "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
8
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 49: Hindbrain - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
5
2
4
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,567
8
ENSG00000170439
METTL7B
Methyltransferase like 7B
[ "Q6UX53" ]
12
55681736-55684611
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038644" ]
[ "ALDI", "MGC17301" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Methyltransferase", "Transferase" ]
[]
[ "Microtubules" ]
[ "Vesicles" ]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 29: Forebrain - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in some
5
3
0
3
[ "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Thyroid Carcinoma" ]
12,568
2
ENSG00000170442
KRT86
Keratin 86
[ "O43790" ]
12
52249300-52309163
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039798", "HPA049778" ]
[ "Hb6", "KRTHB6", "MNX" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Supported
null
44
null
null
Cluster 41: Basophils - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
35
Group enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
9
0
0
0
[]
[]
[]
12,569
5
ENSG00000170445
HARS1
Histidyl-tRNA synthetase 1
[ "P12081" ]
5
140673035-140691537
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036539" ]
[ "HARS", "HisRS", "USH3B" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Aminoacyl-tRNA synthetase", "Ligase" ]
[ "Charcot-Marie-Tooth disease", "Deafness", "Disease variant", "Neurodegeneration", "Neuropathy", "Retinitis pigmentosa", "Usher syndrome" ]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Approved
null
8
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 1: Neurons - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,570
3
ENSG00000170448
NFXL1
Nuclear transcription factor, X-box binding like 1
[ "Q6ZNB6" ]
4
47847233-47914667
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059132" ]
[ "HOZFP" ]
[ "Predicted membrane proteins", "Transcription factors" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
10
null
null
Cluster 24: Non-specific - Transcription
Cluster 2: Neurons - Nucleosome
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
9
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,571
4
ENSG00000170454
KRT75
Keratin 75
[ "O95678" ]
12
52424070-52434371
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019367", "HPA076201" ]
[ "K6HF" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
130
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
16
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,572
9
ENSG00000170456
DENND5B
DENN domain containing 5B
[ "Q6ZUT9" ]
12
31382226-31591136
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038865" ]
[ "MGC24039" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Microtubules" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 16: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
12,573
2
ENSG00000170458
CD14
CD14 molecule
[ "P08571" ]
5
140631728-140633700
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001887", "HPA002127", "CAB033631", "CAB072865", "CAB072866" ]
[]
[ "Cancer-related genes", "CD markers", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins", "Transporters" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
Approved
Enhanced
null
7
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 27: Breast cancer - Unknown function
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Immune cell enhanced
Detected in all
null
2
0
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,574
6
ENSG00000170468
RIOX1
Ribosomal oxygenase 1
[ "Q9H6W3" ]
14
73490933-73493394
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003730" ]
[ "C14orf169", "FLJ21802", "JMJD9", "MAPJD", "NO66" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Dioxygenase", "Oxidoreductase", "Repressor" ]
[]
[ "Nucleoli rim" ]
[]
[]
[]
Supported
null
null
1
null
null
Cluster 29: Non-specific - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 30: Non-specific - Gene expression regulation
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,577
1
ENSG00000170469
SPATA24
Spermatogenesis associated 24
[ "Q86W54" ]
5
139396563-139404089
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044000" ]
[ "CCDC161", "T6441" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
9
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 46: Brainstem - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in all
6
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
8
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,578
6
ENSG00000170473
PYM1
PYM homolog 1, exon junction complex associated factor
[ "Q9BRP8" ]
12
55901413-55932618
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012803", "HPA039717", "HPA046200" ]
[ "PYM", "WIBG" ]
[ "Predicted intracellular proteins" ]
[ "Nonsense-mediated mRNA decay", "Translation regulation" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm", "Nucleoli", "Cytosol" ]
[ "Cell Junctions" ]
[]
[]
Supported
Supported
null
16
No
No
Cluster 12: Non-specific - Mitochondrial translation
Cluster 44: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,580
3
ENSG00000170476
MZB1
Marginal zone B and B1 cell specific protein
[ "Q8WU39" ]
5
139387467-139390081
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043745", "HPA052694" ]
[ "HSPC190", "MEDA-7", "MGC29506", "PACAP", "pERp1" ]
[ "Predicted secreted proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "Other" ]
Approved
Enhanced
null
6
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 8: Immune cells - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
5
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
8
Group enriched
Detected in many
5
3
0
3
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,581
6
ENSG00000170477
KRT4
Keratin 4
[ "P19013" ]
12
52806549-52814116
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002154", "HPA034881" ]
[ "CK4", "CYK4", "K4" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Intermediate filaments" ]
[]
[]
[]
Supported
Enhanced
null
28
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enriched
Detected in many
5
Group enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,582
3
ENSG00000170482
SLC23A1
Solute carrier family 23 member 1
[ "Q9UHI7" ]
5
139367196-139384553
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047612" ]
[ "SLC23A2", "SVCT1", "YSPL3" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Sodium transport", "Symport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
12
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 46: Brainstem - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 26: Kidney & Intestine - Metabolism
Group enriched
Detected in many
7
Group enriched
Detected in many
4
Group enriched
Detected in many
5
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
12,583
8
ENSG00000170484
KRT74
Keratin 74
[ "Q7RTS7" ]
12
52565782-52573843
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040655", "HPA048596" ]
[ "K6IRS4", "KRT5C", "KRT6IRS4" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Ectodermal dysplasia", "Hypotrichosis" ]
[ "Intermediate filaments" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Enhanced
null
16
null
null
null
null
Cluster 32: Non-specific - Cell proliferation
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 9: Skin - Hair follicle development
Group enriched
Detected in some
13
Cancer enriched
Detected in single
4
Not detected
Not detected
null
Group enriched
Detected in some
9
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,584
9
ENSG00000170485
NPAS2
Neuronal PAS domain protein 2
[ "Q99743" ]
2
100820139-100996829
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA019674" ]
[ "bHLHe9", "MOP4", "PASD4" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Biological rhythms", "DNA damage", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
Supported
18
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Breast Invasive Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,585
1
ENSG00000170486
KRT72
Keratin 72
[ "Q14CN4" ]
12
52585589-52601538
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065523" ]
[ "K6irs", "K6IRS2", "KRT6", "KRT6IRS2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
22
null
null
null
null
Cluster 59: Leukemia - T-cell receptor
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 47: Testis - Mixed function
Group enriched
Detected in some
6
Cancer enriched
Detected in single
17
Not detected
Not detected
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,586
2
ENSG00000170498
KISS1
KiSS-1 metastasis suppressor
[ "Q15726" ]
1
204190341-204196491
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017775", "HPA035542" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[]
[ "Cancer-related genes", "Disease variant", "Hypogonadotropic hypogonadism" ]
[ "Vesicles" ]
[]
[ "Secreted in female reproductive system" ]
[ "No annotated function" ]
Approved
Enhanced
null
7
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 72: Neuronal - Signal transduction
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in some
30
Cancer enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
40
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,587
5
ENSG00000170500
LONRF2
LON peptidase N-terminal domain and ring finger 2
[ "Q1L5Z9" ]
2
100271875-100322501
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034595", "HPA057366" ]
[ "FLJ45273", "RNF192" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
15
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 5: Rhabdoid - Unknown function
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enriched
Detected in many
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,588
9
ENSG00000170502
NUDT9
Nudix hydrolase 9
[ "Q9BW91" ]
4
87422573-87459455
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036917", "HPA044866", "HPA078535" ]
[ "MGC3037" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nuclear bodies", "Mitochondria" ]
[ "Nuclear membrane", "Cell Junctions" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Approved
null
5
null
null
Cluster 33: Non-specific - ATP binding
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
12,589
5
ENSG00000170509
HSD17B13
Hydroxysteroid 17-beta dehydrogenase 13
[ "Q7Z5P4" ]
4
87303789-87322886
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029125" ]
[ "SCDR9", "SDR16C3" ]
[ "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Vesicles" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
110
null
null
Cluster 22: Eosinophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 10: Ciliated cells - Ion channel activity
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in many
61
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
22
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,590
1
ENSG00000170515
PA2G4
Proliferation-associated 2G4
[ "Q9UQ80" ]
12
56104537-56113910
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011711", "CAB012428", "HPA016484" ]
[ "EBP1" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "rRNA processing", "Transcription", "Transcription regulation", "Translation regulation" ]
[ "Repressor", "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Supported
null
79
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 28: Oligodendrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
4
1
[]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,591
5
ENSG00000170516
COX7B2
Cytochrome c oxidase subunit 7B2
[ "Q8TF08" ]
4
46734827-46909245
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Evidence at protein level
[]
[]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 51: Myeloma - Immunoglobulins
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in some
69
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,592
6
ENSG00000170522
ELOVL6
ELOVL fatty acid elongase 6
[ "Q9H5J4" ]
4
110045846-110199199
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042355" ]
[ "FLJ23378", "LCE", "MGC5487" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
Cluster 15: NK-cells - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
2
2
1
[ "Colon Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
12,593
5
ENSG00000170523
KRT83
Keratin 83
[ "P78385" ]
12
52314301-52321398
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049778" ]
[ "Hb-3", "KRTHB3" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Palmoplantar keratoderma" ]
[]
[]
[]
[]
null
Supported
null
37
null
null
null
Cluster 30: White matter - Myelination
Cluster 7: Liver cancer - Metabolism
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
30
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,594
5