ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000174953
DHX36
DEAH-box helicase 36
[ "Q9H2U1" ]
3
154272546-154324487
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035399" ]
[ "DDX36", "KIAA1488", "MLEL1", "RHAU" ]
[ "Enzymes", "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Antiviral defense", "Differentiation", "Immunity", "Innate immunity", "Transcription", "Transcription regulation", "Translation regulation", "Transport" ]
[ "Activator", "Developmental protein", "DNA-binding", "Helicase", "Hydrolase", "Repressor", "RNA-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
17
null
null
Cluster 24: Non-specific - Transcription
Cluster 55: Non-specific - Transcription
Cluster 63: Non-specific - Protein processing
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
13,476
3
ENSG00000174957
OR5J2
Olfactory receptor family 5 subfamily J member 2
[ "Q8NH18" ]
11
56176618-56177556
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
[ "HPA059466" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 69: Skin cancer - ECM organization
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,477
8
ENSG00000174963
ZIC4
Zic family member 4
[ "Q8N9L1" ]
3
147386046-147406809
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA030194" ]
[]
[ "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 5: Rhabdoid - Unknown function
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in some
20
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,478
1
ENSG00000174989
FBXW8
F-box and WD repeat domain containing 8
[ "Q8N3Y1" ]
12
116910950-117031148
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038850", "HPA038851" ]
[ "FBW6", "FBW8", "FBX29", "FBXO29" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Supported
null
21
null
null
Cluster 14: Non-specific - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 38: Non-specific - Transcription
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
13,481
2
ENSG00000174990
CA5A
Carbonic anhydrase 5A
[ "P35218" ]
16
87881546-87936580
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CA5", "CAV", "CAVA" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Lyase" ]
[ "Disease variant", "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in single
57
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in single
68
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,482
6
ENSG00000174992
ZG16
Zymogen granule protein 16
[ "O60844" ]
16
29778256-29782973
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052066", "HPA052512" ]
[ "hZG16", "JCLN", "JCLN1", "ZG16A" ]
[ "Predicted secreted proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Annulus" ]
[ "Mid piece", "Principal piece" ]
[ "Secreted to digestive system" ]
[ "Transport" ]
Approved
Enhanced
null
9
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
22
Not detected
Not detected
null
Group enriched
Detected in some
7
Cell type enriched
Detected in some
52
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,483
1
ENSG00000174996
KLC2
Kinesin light chain 2
[ "Q9H0B6" ]
11
66257294-66267860
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040416", "HPA040434" ]
[ "FLJ12387" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Motor protein" ]
[ "Hereditary spastic paraplegia", "Neurodegeneration", "Neuropathy" ]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
Supported
Approved
null
50
null
null
Cluster 24: Non-specific - Transcription
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
13,484
1
ENSG00000175003
SLC22A1
Solute carrier family 22 member 1
[ "O15245" ]
6
160121815-160158718
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029846" ]
[ "OCT1" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
4
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 51: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in some
400
Not detected
Not detected
null
Cancer enriched
Detected in some
65
Cell type enriched
Detected in many
10
Immune cell enriched
Detected in single
12
1
2
0
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,485
2
ENSG00000175018
TEX36
Testis expressed 36
[ "Q5VZQ5" ]
10
125576522-125683163
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA077263" ]
[ "bA383C5.1", "C10orf122" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
null
null
null
null
null
null
null
Cluster 64: Connective tissue cells - ECM organization
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
54
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
96
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,486
2
ENSG00000175029
CTBP2
C-terminal binding protein 2
[ "P56545" ]
10
124984317-125161170
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023559", "HPA023564", "CAB031916", "HPA044971", "CAB079018" ]
[ "ribeye" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Oxidoreductase", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
Approved
135
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 25: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
2
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,487
4
ENSG00000175040
CHST2
Carbohydrate sulfotransferase 2
[ "Q9Y4C5" ]
3
143119771-143124014
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013620" ]
[ "C6ST" ]
[ "Metabolic proteins", "Predicted membrane proteins" ]
[ "Carbohydrate metabolism", "Inflammatory response" ]
[ "Transferase" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
null
null
null
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 27: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
4
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
13,488
7
ENSG00000175048
ZDHHC14
Zinc finger DHHC-type palmitoyltransferase 14
[ "Q8IZN3" ]
6
157381133-157678157
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013437", "HPA063754" ]
[ "FLJ20984", "NEW1CP" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Approved
null
1
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 21: Lymphoma - Adaptive immune response
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,489
2
ENSG00000175054
ATR
ATR serine/threonine kinase
[ "Q13535" ]
3
142449007-142578733
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054320" ]
[ "FRP1", "MEC1", "SCKL", "SCKL1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins" ]
[ "DNA damage", "DNA repair" ]
[ "DNA-binding", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes", "Disease variant", "Dwarfism", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Supported
null
null
53
No
No
Cluster 33: Non-specific - ATP binding
Cluster 21: Non-specific - Metabolism
Cluster 63: Non-specific - Protein processing
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
13,490
4
ENSG00000175063
UBE2C
Ubiquitin conjugating enzyme E2 C
[ "O00762" ]
20
45812576-45816957
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011464", "HPA034569", "CAB035990", "HPA054975", "CAB080407" ]
[ "UBCH10" ]
[ "Cancer-related genes", "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis", "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
15
Yes
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 48: Non-specific - Mixed function
Cluster 62: Non-specific - Plasma proteins
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
6
8
2
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,491
6
ENSG00000175066
GK5
Glycerol kinase 5
[ "Q6ZS86" ]
3
142157527-142225592
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042606", "HPA057998" ]
[ "MGC40579" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Glycerol metabolism" ]
[ "Kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 20: Non-specific - DNA binding
Cluster 50: Non-specific - Nucleic acid binding
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
13,493
8
ENSG00000175073
VCPIP1
Valosin containing protein interacting protein 1
[ "Q96JH7" ]
8
66628487-66667231
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA023932" ]
[ "DUBA3", "FLJ23132", "KIAA1850", "VCIP135" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Plasma membrane" ]
[ "Centrosome", "Cytosol" ]
[]
[]
Uncertain
Uncertain
null
43
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 34: Non-specific - Mixed function
Cluster 40: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Bladder Urothelial Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
13,494
2
ENSG00000175077
RTP1
Receptor transporter protein 1
[ "P59025" ]
3
187197486-187201462
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "MGC35450", "Z3CXXC1" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 3: Rhabdoid - Membrane components
Cluster 41: Oocytes - Oogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in single
null
Group enriched
Detected in some
26
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,495
2
ENSG00000175084
DES
Desmin
[ "P17661" ]
2
219418377-219426735
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000034", "HPA018803" ]
[ "CMD1I", "CSM1", "CSM2" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Muscle protein" ]
[ "Cancer-related genes", "Cardiomyopathy", "Desmin-related myopathy", "Disease variant", "Limb-girdle muscular dystrophy", "Myofibrillar myopathy" ]
[ "Intermediate filaments" ]
[]
[]
[]
Supported
Enhanced
null
79
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
62
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
7
Not detected in immune cells
Not detected
null
4
0
4
[ "Bladder Urothelial Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
13,496
7
ENSG00000175087
PDIK1L
PDLIM1 interacting kinase 1 like
[ "Q8N165" ]
1
26111165-26125555
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064157" ]
[ "CLIK1L" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
17
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 31: Non-specific - Transcription
Cluster 37: Non-specific - mRNA processing
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,497
7
ENSG00000175097
RAG2
Recombination activating 2
[ "P55895" ]
11
36575574-36598279
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA065704" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "DNA recombination" ]
[ "Chromatin regulator" ]
[ "Disease variant", "SCID" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
3
null
null
null
null
Cluster 6: Leukemia - Signal transduction
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 80: Thymus - Adaptive immune response
Tissue enriched
Detected in some
6
Group enriched
Detected in some
56
Cancer enriched
Detected in single
23
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,499
4
ENSG00000175106
TVP23C
Trans-golgi network vesicle protein 23 homolog C
[ "Q96ET8" ]
17
15502264-15563595
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019585", "HPA065603" ]
[ "FAM18B2", "MGC8763" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Uncertain
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 42: Non-specific - Unknown function
Cluster 22: Non-specific - Basic cellular functions
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
21
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
13,502
1
ENSG00000175110
MRPS22
Mitochondrial ribosomal protein S22
[ "P82650" ]
3
139005806-139360497
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006083", "HPA007830" ]
[ "C3orf5", "GIBT", "GK002", "MRP-S22" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Enhanced
null
79
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 97: Non-specific - Cellular respiration
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,503
8
ENSG00000175115
PACS1
Phosphofurin acidic cluster sorting protein 1
[ "Q6VY07" ]
11
66070272-66244744
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038914", "HPA075046" ]
[ "FLJ10209", "KIAA1175" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
Approved
Approved
null
12
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 33: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
2
1
[]
[ "Lung Adenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Stomach Adenocarcinoma" ]
13,504
7
ENSG00000175121
WFDC5
WAP four-disulfide core domain 5
[ "Q8TCV5" ]
20
45109452-45115174
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "dJ211D12.5", "WAP1" ]
[ "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme inhibitor" ]
null
null
null
4
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 26: Keratinocytes - Keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
30
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
13,505
6
ENSG00000175130
MARCKSL1
MARCKS like 1
[ "P49006" ]
1
32333839-32336233
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB020787", "HPA030528" ]
[ "F52", "MacMARCKS", "MLP", "MLP1" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Calmodulin-binding" ]
[]
[ "Plasma membrane" ]
[ "Endoplasmic reticulum", "Cytokinetic bridge", "Mitotic spindle", "Primary cilium" ]
[]
[]
Approved
Enhanced
null
18
Yes
Yes
Cluster 22: Eosinophils - Transcription
Cluster 30: White matter - Myelination
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 15: Non-specific - Protein processing
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in all
8
2
2
1
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
13,506
6
ENSG00000175137
SH3BP5L
SH3 binding domain protein 5 like
[ "Q7L8J4" ]
1
248810446-248825915
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038067", "HPA038068" ]
[ "KIAA1720" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Nucleoplasm", "Golgi apparatus", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,507
5
ENSG00000175143
OR2T1
Olfactory receptor family 2 subfamily T member 1
[]
1
248403048-248408020
No human protein/transcript evidence
No human protein/transcript evidence
null
null
[]
[ "OR1-25" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,508
6
ENSG00000175155
YPEL2
Yippee like 2
[ "Q96QA6" ]
17
59331655-59401729
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030501", "HPA045621" ]
[ "FKSG4" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 5: Rhabdoid - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,509
4
ENSG00000175161
CADM2
Cell adhesion molecule 2
[ "Q8N3J6" ]
3
84958989-86074429
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA010024" ]
[ "IGSF4D", "Necl-3", "NECL3", "SynCAM2" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 11: Neuronal - Sensory perception
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in many
15
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
8
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
6
0
0
0
[]
[]
[]
13,510
2
ENSG00000175164
ABO
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
[]
9
133233278-133276024
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "A3GALNT", "A3GALT1" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to blood" ]
[]
null
null
null
null
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,511
8
ENSG00000175166
PSMD2
Proteasome 26S subunit ubiquitin receptor, non-ATPase 2
[ "Q13200" ]
3
184299198-184309050
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045192", "HPA062363" ]
[ "MGC14274", "P97", "Rpn1", "S2", "TRAP2" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Centriolar satellite", "Cytosol", "Flagellar centriole" ]
[ "Nucleoplasm", "Cytokinetic bridge" ]
[]
[]
Approved
Enhanced
null
223
Yes
null
Cluster 25: Non-specific - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,512
7
ENSG00000175175
PPM1E
Protein phosphatase, Mg2+/Mn2+ dependent 1E
[ "Q8WY54" ]
17
58755854-58985179
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018462", "HPA019263" ]
[ "CaMKP-N", "KIAA1072", "POPX1", "PP2CH" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoli" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
4
Yes
No
Cluster 32: Basophils - Transcription
Cluster 29: Forebrain - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
7
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
13,513
7
ENSG00000175183
CSRP2
Cysteine and glycine rich protein 2
[ "Q16527" ]
12
76858709-76879023
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA045617" ]
[ "CRP2", "LMO5", "SmLIM" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Uncertain
null
5
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,515
8
ENSG00000175189
INHBC
Inhibin subunit beta C
[ "P55103" ]
12
57434784-57452062
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA050755" ]
[]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor", "Hormone" ]
[]
[ "Cytosol" ]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
Approved
null
null
null
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
138
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in single
69
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,516
1
ENSG00000175193
PARL
Presenilin associated rhomboid like
[ "Q9H300" ]
3
183829271-183884933
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019545" ]
[ "PRO2207", "PSARL", "PSARL1", "RHBDS1" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
5
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 63: Non-specific - Protein processing
Cluster 22: Non-specific - Basic cellular functions
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
13,517
7
ENSG00000175197
DDIT3
DNA damage inducible transcript 3
[ "P35638" ]
12
57516588-57521737
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058416", "HPA068416" ]
[ "CHOP", "CHOP10", "GADD153" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Apoptosis", "Cell cycle", "Growth arrest", "Stress response", "Transcription", "Transcription regulation", "Unfolded protein response", "Wnt signaling pathway" ]
[ "Activator", "DNA-binding", "Repressor" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
73
No
No
Cluster 21: Neutrophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
5
Immune cell enhanced
Detected in all
null
3
0
3
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
13,518
1
ENSG00000175198
PCCA
Propionyl-CoA carboxylase subunit alpha
[ "P05165" ]
13
100089015-100530437
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041716", "HPA047792" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Ligase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Enhanced
null
8
null
null
Cluster 33: Non-specific - ATP binding
Cluster 25: Non-specific - Transcription
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
13,519
8
ENSG00000175203
DCTN2
Dynactin subunit 2
[ "Q13561" ]
12
57529633-57547224
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039715", "HPA040040" ]
[ "DCTN-50", "RBP50" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centrosome", "Basal body" ]
[ "Cytosol", "Connecting piece", "Mid piece", "Principal piece", "End piece" ]
[]
[]
Supported
Enhanced
null
103
null
null
Cluster 29: Non-specific - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,521
9
ENSG00000175206
NPPA
Natriuretic peptide A
[ "P01160" ]
1
11845709-11848345
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058269", "HPA064007" ]
[ "ANP", "PND" ]
[ "Candidate cardiovascular disease genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hormone", "Vasoactive", "Vasodilator" ]
[ "Atrial fibrillation", "Cardiomyopathy", "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
null
12
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 35: Non-specific - Mixed function
Tissue enriched
Detected in many
889
Cancer enriched
Detected in some
5
Cancer enriched
Detected in some
10
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
13,522
3
ENSG00000175213
ZNF408
Zinc finger protein 408
[ "Q9H9D4" ]
11
46701030-46705912
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017892" ]
[ "FLJ12827" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Centriolar satellite", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
64
null
null
Cluster 33: Non-specific - ATP binding
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
13,523
9
ENSG00000175215
CTDSP2
CTD small phosphatase 2
[ "O14595" ]
12
57819927-57846729
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052607" ]
[ "OS4", "PSR2", "SCP2" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Approved
Uncertain
null
11
null
null
Cluster 41: Basophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,524
2
ENSG00000175216
CKAP5
Cytoskeleton associated protein 5
[ "Q14008" ]
11
46743048-46846308
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039377", "HPA040375" ]
[ "ch-TOG", "KIAA0097", "TOG", "TOGp" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[ "Centrosome", "Basal body" ]
[ "Nucleoli", "Nucleoli rim", "Plasma membrane", "Mitotic spindle", "Primary cilium" ]
[]
[]
Approved
Supported
null
38
Yes
Yes
Cluster 3: Non-specific - Nuclear processes
Cluster 34: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,525
7
ENSG00000175220
ARHGAP1
Rho GTPase activating protein 1
[ "Q07960" ]
11
46677080-46700619
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004689", "HPA008285" ]
[ "CDC42GAP", "p50rhoGAP", "RhoGAP" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Cytosol" ]
[ "Vesicles", "Primary cilium" ]
[]
[]
Supported
Approved
Approved
29
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 24: Non-specific - Unknown function
Cluster 110: Mural cells - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,526
8
ENSG00000175221
MED16
Mediator complex subunit 16
[ "Q9Y2X0" ]
19
867630-893218
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030685", "HPA046495" ]
[ "DRIP92", "THRAP5", "TRAP95" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Nucleoli" ]
[]
[]
[]
Approved
Uncertain
null
83
null
null
Cluster 25: Non-specific - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,527
4
ENSG00000175224
ATG13
Autophagy related 13
[ "O75143" ]
11
46617527-46674818
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039350" ]
[ "KIAA0652" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transporters" ]
[ "Autophagy" ]
[]
[ "Cancer-related genes" ]
[ "Cytosol" ]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
Supported
null
null
172
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 11: White matter - Signal transduction
Cluster 24: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
13,528
6
ENSG00000175229
GAL3ST3
Galactose-3-O-sulfotransferase 3
[ "Q96A11" ]
11
66040765-66049161
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "GAL3ST2" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
13,529
9
ENSG00000175262
C1orf127
Chromosome 1 open reading frame 127
[]
1
10946471-10982076
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA027654" ]
[ "FLJ37118" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear speckles", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Cancer enriched
Detected in single
8
Group enriched
Detected in some
4
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
13,530
7
ENSG00000175264
CHST1
Carbohydrate sulfotransferase 1
[ "O43916" ]
11
45647689-45665622
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA060313", "HPA072592" ]
[ "C6ST", "KSGal6ST" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Carbohydrate metabolism", "Inflammatory response" ]
[ "Transferase" ]
[]
[ "Mitochondria" ]
[ "Nucleoli" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
null
null
2
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,531
5
ENSG00000175265
GOLGA8A
Golgin A8 family member A
[ "A7E2F4" ]
15
34378935-34437808
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA051808" ]
[ "CFAP286", "FAP286", "GM88", "GOLGIN-67" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
null
null
Yes
null
Cluster 15: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
13,532
1
ENSG00000175267
VWA3A
Von Willebrand factor A domain containing 3A
[ "A6NCI4" ]
16
22092538-22156964
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA041696", "HPA042044" ]
[ "FLJ40941", "FLJ46765" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Uncertain
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
5
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
13
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,533
7
ENSG00000175274
TP53I11
Tumor protein p53 inducible protein 11
[ "O14683" ]
11
44885903-44951306
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059727", "HPA061276" ]
[ "PIG11" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum", "Golgi apparatus" ]
[ "Acrosome", "Principal piece" ]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
13,534
5
ENSG00000175279
CENPS
Centromere protein S
[ "Q8N2Z9" ]
1
10430433-10442808
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "APITD1", "CENP-S", "FAAP16", "MHF1" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "DNA damage", "DNA repair", "Mitosis" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
null
null
29
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 23: Choroid plexus - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
5
0
5
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Skin Cutaneous Melanoma" ]
13,535
4
ENSG00000175283
DOLK
Dolichol kinase
[ "Q9UPQ8" ]
9
128945530-128947603
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066767", "HPA068706" ]
[ "DK1", "KIAA1094", "TMEM15" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Kinase", "Transferase" ]
[ "Congenital disorder of glycosylation", "Disease variant" ]
[ "Nucleoplasm", "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
27
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 19: Astrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
13,536
6
ENSG00000175287
PHYHD1
Phytanoyl-CoA dioxygenase domain containing 1
[ "Q5SRE7" ]
9
128920966-128942041
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012115" ]
[ "MGC16638" ]
[ "Predicted intracellular proteins" ]
[]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
null
null
3
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 31: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
4
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
13,537
7
ENSG00000175294
CATSPER1
Cation channel sperm associated 1
[ "Q8NEC5" ]
11
66016752-66026479
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044528" ]
[ "CATSPER" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Calcium transport", "Differentiation", "Ion transport", "Spermatogenesis", "Transport" ]
[ "Calcium channel", "Developmental protein", "Ion channel", "Voltage-gated channel" ]
[]
[ "Principal piece" ]
[]
[]
[]
Supported
null
null
97
null
null
Cluster 41: Basophils - Unknown function
null
Cluster 72: Neuronal - Signal transduction
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
33
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
13,538
6
ENSG00000175305
CCNE2
Cyclin E2
[ "O96020" ]
8
94879770-94896678
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB007825", "CAB019374" ]
[ "CYCE2" ]
[ "Cancer-related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[ "Cyclin" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Enhanced
null
23
null
Yes
Cluster 9: T-regs - Cell cycle regulation
Cluster 30: White matter - Myelination
Cluster 10: Ciliated cells - Ion channel activity
Cluster 65: Non-specific - Cell growth & division
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
3
2
2
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
13,539
9
ENSG00000175309
PHYKPL
5-phosphohydroxy-L-lysine phospho-lyase
[ "Q8IUZ5" ]
5
178208471-178232802
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036461", "HPA063608" ]
[ "AGXT2L2", "MGC15875" ]
[ "Disease related genes", "Enzymes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Lyase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
8
Yes
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 6: Non-specific - Immune response
Cluster 71: Lymphoma - Inflammatory response
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 26: Kidney & Intestine - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,540
4
ENSG00000175311
ANKS4B
Ankyrin repeat and sterile alpha motif domain containing 4B
[ "Q8N8V4" ]
16
21233699-21253850
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043523", "HPA061125" ]
[ "FLJ38819", "HARP" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
2
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 10: Ciliated cells - Ion channel activity
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 77: Intestine - Digestion
Group enriched
Detected in some
7
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
9
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,541
2
ENSG00000175315
CST6
Cystatin E/M
[ "Q15828" ]
11
66012008-66013505
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB019316", "HPA044963" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Thiol protease inhibitor" ]
[ "Cancer-related genes", "Disease variant", "Ectodermal dysplasia" ]
[ "Plasma membrane" ]
[ "Cytosol" ]
[ "Secreted in other tissues" ]
[ "Enzyme inhibitor" ]
Approved
Enhanced
null
22
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in many
21
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
5
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,542
2
ENSG00000175322
ZNF519
Zinc finger protein 519
[ "Q8TB69" ]
18
14057457-14132490
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA028982" ]
[ "FLJ36809", "HsT2362" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoli" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 4: Non-specific - Transcription
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
13,544
7
ENSG00000175324
LSM1
LSM1 homolog, mRNA degradation associated
[ "O15116" ]
8
38163335-38176730
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024601" ]
[ "CASM", "YJL124C" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Cytoplasmic bodies" ]
[ "Cytosol" ]
[]
[]
Approved
null
null
58
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 21: Non-specific - Metabolism
Cluster 40: Non-specific - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme" ]
13,545
1
ENSG00000175325
PROP1
PROP paired-like homeobox 1
[ "O75360" ]
5
177992235-177996242
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049839" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[ "Disease variant", "Dwarfism" ]
[]
[]
[]
[]
null
Enhanced
null
42
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 20: Pituitary gland - Hormone signaling
Tissue enriched
Detected in single
7
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,546
2
ENSG00000175329
ISX
Intestine specific homeobox
[ "Q2M1V0" ]
22
35066136-35087387
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA060328" ]
[ "RAXLX" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
null
null
12
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in single
70
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,547
9
ENSG00000175336
APOF
Apolipoprotein F
[ "Q13790" ]
12
56360568-56362857
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Plasma proteins", "Predicted secreted proteins" ]
[ "Cholesterol metabolism", "Lipid metabolism", "Lipid transport", "Steroid metabolism", "Sterol metabolism", "Transport" ]
[]
[]
[]
[]
[ "Secreted to blood" ]
[ "Apolipoprotein" ]
null
null
null
2
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
343
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in some
5
Cell type enriched
Detected in some
30
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,549
5
ENSG00000175344
CHRNA7
Cholinergic receptor nicotinic alpha 7 subunit
[ "P36544" ]
15
31923438-32173018
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029422", "CAB033624" ]
[]
[ "FDA approved drug targets", "Human disease related genes", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
9
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,550
2
ENSG00000175348
TMEM9B
TMEM9 domain family member B
[ "Q9NQ34" ]
11
8947202-8965011
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037784" ]
[ "C11orf15" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
65
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 39: Astrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,551
8
ENSG00000175352
NRIP3
Nuclear receptor interacting protein 3
[ "Q9NQ35" ]
11
8965682-9005288
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058827", "HPA072961" ]
[ "C11orf14" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
8
null
null
Cluster 46: Basophils - Proteolysis
Cluster 29: Forebrain - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 109: Neurons - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
6
0
0
0
[]
[]
[]
13,552
2
ENSG00000175354
PTPN2
Protein tyrosine phosphatase non-receptor type 2
[ "P17706" ]
18
12785478-12929643
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015004", "HPA046176" ]
[ "PTPT", "TC-PTP", "TCELLPTP", "TCPTP" ]
[ "Enzymes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
41
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 71: Lymphoma - Inflammatory response
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,553
9
ENSG00000175356
SCUBE2
Signal peptide, CUB domain and EGF like domain containing 2
[ "Q9NQ36" ]
11
9019476-9138114
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006353", "HPA029871" ]
[ "Cegb1", "Cegf1", "FLJ16792" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Developmental protein" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Developmental protein" ]
null
Uncertain
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 27: Breast cancer - Unknown function
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
5
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
13,554
6
ENSG00000175376
EIF1AD
Eukaryotic translation initiation factor 1A domain containing
[ "Q8N9N8" ]
11
65996545-66002176
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA054991", "HPA058735" ]
[ "haponin", "MGC11102" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
41
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 24: Non-specific - Unknown function
Cluster 75: Non-specific - Chaperones and protein folding
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,555
1
ENSG00000175387
SMAD2
SMAD family member 2
[ "Q15796" ]
18
47808957-47931146
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025507", "HPA067203", "CAB073546" ]
[ "JV18-1", "MADH2", "MADR2" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Heterotaxy" ]
[ "Nucleoplasm", "Nucleoli" ]
[ "Vesicles", "Primary cilium transition zone", "Cytosol" ]
[]
[]
Supported
Approved
null
109
null
null
Cluster 33: Non-specific - ATP binding
Cluster 27: Non-specific - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,556
7
ENSG00000175390
EIF3F
Eukaryotic translation initiation factor 3 subunit F
[ "O00303" ]
11
7970251-8001862
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049250" ]
[ "eIF3-epsilon", "eIF3-p47", "EIF3S5" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Protein biosynthesis", "Ubl conjugation pathway" ]
[ "Hydrolase", "Initiation factor", "Protease", "Thiol protease" ]
[ "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
Approved
null
123
null
null
Cluster 33: Non-specific - ATP binding
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,557
7
ENSG00000175395
ZNF25
Zinc finger protein 25
[ "P17030" ]
10
37949573-37976647
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030190" ]
[ "FLJ31890", "KOX19", "Zfp9" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 1: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
13,558
3
ENSG00000175416
CLTB
Clathrin light chain B
[ "P09497" ]
5
176392501-176416539
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003692", "HPA036458" ]
[ "Lcb" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[]
[]
[]
[ "Vesicles" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Supported
Approved
null
79
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
13,561
3
ENSG00000175426
PCSK1
Proprotein convertase subtilisin/kexin type 1
[ "P29120" ]
5
96390333-96434143
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048564", "HPA079656" ]
[ "NEC1", "PC1", "PC1/3", "PC3", "SPC3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[ "Disease variant", "Obesity" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme" ]
null
Approved
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
13,562
8
ENSG00000175445
LPL
Lipoprotein lipase
[ "P06858" ]
8
19901717-19967259
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048749" ]
[ "LIPD" ]
[ "Candidate cardiovascular disease genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Heparin-binding", "Hydrolase" ]
[ "Disease variant", "FDA approved drug targets", "Hyperlipidemia" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
Approved
null
null
13
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 12: Bone cancer - Neuronal signaling
Cluster 89: Adipocytes - Lipid metabolism
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Immune cell enhanced
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Stomach Adenocarcinoma" ]
13,563
8
ENSG00000175449
RFESD
Rieske Fe-S domain containing
[ "Q8TAC1" ]
5
95646777-95684773
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016546" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 11: T-cells - Unknown function
Cluster 50: Non-specific - Nucleic acid binding
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
13,564
3
ENSG00000175455
CCDC14
Coiled-coil domain containing 14
[ "Q49A88" ]
3
123897305-123961408
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035278", "HPA035279" ]
[ "DKFZp434L1050", "FLJ12892" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centriolar satellite" ]
[ "Microtubules", "Primary cilium", "Basal body" ]
[]
[]
Enhanced
Uncertain
null
36
null
Yes
Cluster 5: Non-specific - Cell proliferation
Cluster 39: Astrocytes - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
13,565
1
ENSG00000175463
TBC1D10C
TBC1 domain family member 10C
[ "Q8IV04" ]
11
67403915-67410089
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069743" ]
[ "Carabin", "EPI64C", "FLJ00332" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nuclear bodies" ]
[]
[]
[]
Approved
Enhanced
null
3
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 8: Immune cells - Immune response
Cluster 59: Leukemia - T-cell receptor
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 66: Lymphoid tissue - Immune response
Group enriched
Detected in many
4
Group enriched
Detected in some
6
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Skin Cutaneous Melanoma" ]
[]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Skin Cutaneous Melanoma" ]
13,566
1
ENSG00000175467
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
[ "O43290" ]
11
65961728-65980137
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031188", "HPA031189", "HPA031190" ]
[ "Ara1", "HAF", "SNRNP110", "Snu66" ]
[ "Cancer-related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[ "Allergen", "Cancer-related genes" ]
[ "Nuclear speckles" ]
[ "Golgi apparatus" ]
[]
[]
Enhanced
Supported
null
127
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,567
4
ENSG00000175471
MCTP1
Multiple C2 and transmembrane domain containing 1
[ "Q6DN14" ]
5
94703690-95285094
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA075887" ]
[ "FLJ22344" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 31: Non-specific - Transcription
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
45
1
0
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
13,569
2
ENSG00000175482
POLD4
DNA polymerase delta 4, accessory subunit
[ "Q9HCU8" ]
11
67350772-67356972
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA078008" ]
[ "p12", "POLDS" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA excision", "DNA repair", "DNA replication" ]
[]
[]
[ "Centriolar satellite" ]
[]
[]
[]
Approved
null
null
12
null
null
Cluster 29: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 26: Kidney & Intestine - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,570
6
ENSG00000175485
OR52W1
Olfactory receptor family 52 subfamily W member 1
[ "Q6IF63" ]
11
6199224-6200186
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "OR52W1P" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,571
7
ENSG00000175489
LRRC25
Leucine rich repeat containing 25
[ "Q8N386" ]
19
18391137-18397622
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029459" ]
[ "FLJ38116", "MAPA" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum", "Microtubules", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
90
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 6: Non-specific - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Group enriched
Detected in many
4
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
8
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
13,572
1
ENSG00000175497
DPP10
Dipeptidyl peptidase like 10
[ "Q8N608" ]
2
114442299-115845780
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048767" ]
[ "DPL2", "DPPY", "DPRP3" ]
[ "Disease related genes", "Enzymes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[ "Asthma" ]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 36: Brain & Liver - Signaling
Group enriched
Detected in some
4
Group enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,573
7
ENSG00000175505
CLCF1
Cardiotrophin like cytokine factor 1
[ "Q9UBD9" ]
11
67364168-67374177
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042444" ]
[ "BSF-3", "BSF3", "CISS2", "CLC", "NNT-1", "NNT1", "NR6" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted secreted proteins" ]
[]
[ "Cytokine" ]
[ "Disease variant" ]
[ "Nuclear bodies", "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Cytokine" ]
Approved
Uncertain
null
2
null
null
Cluster 29: Non-specific - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Rectum Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
13,574
6
ENSG00000175513
TSGA10IP
Testis specific 10 interacting protein
[ "Q3SY00" ]
11
65945480-65959966
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049510" ]
[ "FAM161C", "FLJ32880" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mid piece" ]
[]
[]
[]
Approved
null
null
83
null
null
null
null
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
12
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,575
2
ENSG00000175514
GPR152
G protein-coupled receptor 152
[ "Q8TDT2" ]
11
67451301-67452729
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[ "HPA035078" ]
[ "PGR5" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
164
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,576
6
ENSG00000175518
UBQLNL
Ubiquilin like
[ "Q8IYU4" ]
11
5514393-5518431
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MGC20470", "MGC26958" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
8
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in some
12
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
13
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,577
1
ENSG00000175520
UBQLN3
Ubiquilin 3
[ "Q9H347" ]
11
5507300-5509958
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020547", "HPA062018" ]
[ "TUP-1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
6
null
null
null
Cluster 44: Non-specific - Mixed function
null
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
624
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,578
9
ENSG00000175535
PNLIP
Pancreatic lipase
[ "P16233" ]
10
116545931-116567855
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA062430", "HPA062494" ]
[ "PL" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted secreted proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase" ]
[ "Disease variant", "FDA approved drug targets" ]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
null
Enhanced
null
null
null
null
null
null
Cluster 66: Non-specific - Mitochondria
Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion
Cluster 8: Pancreas - Proteolysis
Tissue enriched
Detected in many
4,835
Not detected
Not detected
null
Cancer enriched
Detected in single
4,399
Cell type enriched
Detected in some
196
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,579
6
ENSG00000175536
LIPT2
Lipoyl(octanoyl) transferase 2
[ "A6NK58" ]
11
74490519-74493724
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040249" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Ligase", "Transferase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 27: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
3
[ "Colon Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,580
7
ENSG00000175544
CABP4
Calcium binding protein 4
[ "P57796" ]
11
67452406-67461752
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CSNB2B" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 6: Non-specific - Immune response
Cluster 70: DU4475 - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in some
6
0
0
0
[]
[]
[]
13,582
5
ENSG00000175548
ALG10B
ALG10 alpha-1,2-glucosyltransferase B
[ "Q5I7T1" ]
12
38316762-38329721
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043329", "HPA063387" ]
[ "KCR1" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Approved
null
2
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 55: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 42: Retina - Visual perception
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,583
7
ENSG00000175550
DRAP1
DR1 associated protein 1
[ "Q14919" ]
11
65919274-65921563
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006790" ]
[ "NC2-alpha" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
29
null
null
Cluster 25: Non-specific - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 26: Keratinocytes - Keratinization
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,584
6
ENSG00000175556
LONRF3
LON peptidase N-terminal domain and ring finger 3
[ "Q496Y0" ]
X
118974614-119018355
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050422", "HPA061162" ]
[ "FLJ22612", "RNF127" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
8
null
null
Cluster 1: T-cells - Unknown function
Cluster 35: Non-specific - DNA binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,585
9
ENSG00000175567
UCP2
Uncoupling protein 2
[ "P55851" ]
11
73974672-73982843
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025583", "HPA075202" ]
[ "BMIQ4", "SLC25A8" ]
[ "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
2
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
13,587
9
ENSG00000175573
C11orf68
Chromosome 11 open reading frame 68
[ "Q9H3H3" ]
11
65916810-65919062
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA045938" ]
[ "BLES03", "P5326" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nucleoli" ]
[ "Nucleoli rim" ]
[]
[]
Approved
Uncertain
null
4
No
Yes
Cluster 35: Neutrophils - Protein binding
Cluster 37: Neurons - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
13,588
8
ENSG00000175581
MRPL48
Mitochondrial ribosomal protein L48
[ "Q96GC5" ]
11
73787872-73865133
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040241", "HPA040864" ]
[ "CGI-118" ]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
48
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
13,590
6
ENSG00000175582
RAB6A
RAB6A, member RAS oncogene family
[ "P20340" ]
11
73675638-73761137
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009936", "HPA059131" ]
[ "RAB6" ]
[ "Predicted intracellular proteins" ]
[ "ER-Golgi transport", "Host-virus interaction", "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[ "Golgi apparatus" ]
[ "Basal body" ]
[]
[]
Supported
Approved
null
33
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 10: Brain - Synaptic signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
13,591
5